Metabolism
Metabolism inhibitors are compounds that interfere with metabolic pathways, altering the production and utilization of energy within cells. These inhibitors are used to study the regulation of metabolism, the role of metabolic pathways in diseases like cancer and diabetes, and to develop new therapeutic strategies. Metabolism inhibitors can target various enzymes and processes involved in glycolysis, fatty acid oxidation, and other metabolic functions. At CymitQuimica, we offer a wide range of high-quality metabolism inhibitors to support your research in biochemistry, metabolic disorders, and drug development.
Subcategories of "Metabolism"
- AhR(42 products)
- Aminopeptidase(76 products)
- CETP(20 products)
- Carbonic Anhydrase(197 products)
- Casein Kinase(139 products)
- DHFR(30 products)
- Decarboxylase(4 products)
- Dehydrogenase(303 products)
- FAAH(64 products)
- FXR(63 products)
- Factor Xa(87 products)
- Fatty Acid Synthase(37 products)
- Ferroptosis(233 products)
- GR(3 products)
- GSNOR(3 products)
- Glucokinase(56 products)
- HIF/HIF Prolyl-Hydroxylase(147 products)
- HMG-CoA Reductase(36 products)
- Hydroxylase(36 products)
- IDO(84 products)
- LDL(7 products)
- Lipase(107 products)
- Lipid(62 products)
- Lipoxygenase(134 products)
- MAO(84 products)
- MPO(2 products)
- NAMPT(40 products)
- P450(6 products)
- PAI-1(26 products)
- PDE(170 products)
- PED(1 products)
- PKM(17 products)
- PPAR(170 products)
- Phospholipase(84 products)
- ROR(47 products)
- Retinoid Receptor(16 products)
- SGK(10 products)
- Thioredoxin(12 products)
- Transferase(30 products)
- Transporter(43 products)
- UGT(4 products)
- Xanthine Oxidase (XO) Inhibitors(9 products)
Show 34 more subcategories
Found 9205 products of "Metabolism"
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JZP-MA-13
JZP-MA-13: selective α/β-hydrolase domain 6 inhibitor, IC 50 392 nM, doesn't inhibit MAGL/ABHD12/FAAH, used in PET imaging.Formula:C14H15FN4O3SColor and Shape:SolidMolecular weight:338.36PF-04279405
CAS:PF-04279405 is a potent and selective glucokinase activator.Formula:C25H25FN4O4Color and Shape:SolidMolecular weight:464.49BI-L 357
CAS:BI-L 357, a prodrug of BL-L 226, is a selective, orally active inhibitor of 5-lipoxygenase.Formula:C18H18O4SColor and Shape:SolidMolecular weight:330.4Zidovudine glucuronide
CAS:Zidovudine glucuronide: an NRTI antiretroviral for HIV/AIDS treatment; blocks HIV reverse transcriptase, stops viral DNA formation.Formula:C16H21N5O10Color and Shape:SolidMolecular weight:443.37RORγt modulator 3
CAS:RORγt modulator 3 is a modulator of retinol-related orphan receptor γt (RORγt) and can be used to study RORγt-mediated diseases such as pain, COPD, inflammationFormula:C25H25ClFN3O4SColor and Shape:SolidMolecular weight:518FC11409B
CAS:FC11409B is a CAIX inhibitor, inhibiting breast cancer invasion and metastasis.Formula:C29H23BF4N2O3SColor and Shape:SolidMolecular weight:566.38LY 113174
CAS:LY 113174, a novel nonsteroidal aromatase inhibitor, may prove useful in the treatment of estrogen-dependent diseases.Formula:C17H10Cl2N2Color and Shape:SolidMolecular weight:313.18hCA I-IN-2
CAS:hCA I-IN-2 (6d) inhibits hCA I (Ki: 18.8 nM) more selectively over II, IX, XII (Ki: 375.1, 1721, 283.9 nM).Formula:C26H20BrN5O3SColor and Shape:SolidMolecular weight:562.44MK-0952
CAS:MK-0952 treats memory loss and cognitive issues; it's a potent, selective PDE4 inhibitor with restricted blood activity.Formula:C28H22FN3O4Color and Shape:SolidMolecular weight:483.49Lombricine
CAS:Lombricine, as a phosphodiester of 2-guanidinoethanol and D-serine in structure, is a phosphagen that is unique to earthworms.Formula:C6H15N4O6PColor and Shape:SolidMolecular weight:270.183-Oxo-hop-22(29)-ene
CAS:3-Oxo-hop-22(29)-ene inhibits yeast α-glucosidase, moderately affects T. cruzi and L. mexicana, and has slight anti-inflammatory activity.Formula:C30H48OColor and Shape:SolidMolecular weight:424.7LEO 39652
CAS:LEO 39652: Dual-soft PDE4 inhibitor, IC50s: PDE4A/B: 1.2 nM, PDE4C: 3.0 nM, PDE4D: 3.8 nM; TNF-α IC50: 6.0 nM; for Atopic dermatitis research.Formula:C23H23N3O5Color and Shape:SolidMolecular weight:421.45AMPD2 inhibitor 2
AMPD2 inhibitor 2: strong h/mAMPD2 blocker, IC50s: 0.1/0.28μM. Potentially assesses AMPD2's role in high-fat diet mice.Formula:C26H27F2N3O3Color and Shape:SolidMolecular weight:467.51Glucocerebrosidase-IN-1
CAS:Glucocerebrosidase-IN-1 inhibits GCase with IC50 of 29.3 μM, Ki 18.5 μM, useful for Gaucher's and Parkinson's research.Formula:C13H27NO3Color and Shape:SolidMolecular weight:245.36BMS-351
CAS:BMS-351: potent, selective CYP17A1 inhibitor, promising for prostate cancer, minimal side effects.Formula:C15H12F3N3Color and Shape:SolidMolecular weight:291.27FASN-IN-4
CAS:FAS-IN-1 is a potent inhibitor of Fatty acid synthase (FAS) wtih IC50 of 10 nM.Formula:C26H27N3O4SPurity:98%Color and Shape:SolidMolecular weight:477.5811β-HSD1-IN-9
CAS:11β-HSD1-IN-9 is a potent inhibitor of 11β-HSD1, displaying IC50 values of 0.48 µM for human and 1.3 µM for murine variants, respectively.Formula:C13H9F3N2OColor and Shape:SolidMolecular weight:266.22CL 242817
CAS:CL 242817 is an inhibitor of angiotensin converting enzyme (ACE).Formula:C18H21NO5SColor and Shape:SolidMolecular weight:363.4311β-HSD1-IN-6
CAS:11β-HSD1-IN-6 is a potent inhibitor of 11β hydroxysteroid dehydrogenase enzymes (11β-HSDs).Formula:C21H19ClN4OColor and Shape:SolidMolecular weight:378.8614(S)-HDHA
CAS:DHA is an ω-3 important for development and therapy for inflammation and cancer; its derivative, 14(S)-HDHA, aids in reducing inflammation.Formula:C22H32O3Color and Shape:SolidMolecular weight:344.49Oxythiamine diphosphate
CAS:Oxythiamine diphosphate is a competitivethiamine pyrophosphate inhibitor(Ki of 30 nM).Formula:C12H17N3O8P2SPurity:98%Color and Shape:SolidMolecular weight:425.29CM39
CAS:CM39 inhibits ALDH, linked to cancer stem-like cells & chemoresistance.Formula:C19H15FN4OSColor and Shape:SolidMolecular weight:366.41CYP1B1-IN-3
CAS:CYP1B1-IN-3: strong CYP1B1 inhibitor (IC50: 6.6 nM); weak on CYP1A1/CYP1A2; hinders cell migration, invasion; blocks P-gp, AKT/ERK, FAK/SRC, EMT.Formula:C20H16FN3O2S2Color and Shape:SolidMolecular weight:413.49ACC1/2-IN-2
CAS:PF-3: potent ACC1/2 inhibitor; IC50: 22 nM (ACC1), 48 nM (ACC2); anti-cancer research potential.Formula:C24H25N3O3Color and Shape:SolidMolecular weight:403.47Protizinic acid
CAS:Protizinic acid is an oral NSAID with anti-inflammatory and antipyretic properties, inhibiting PLA2 at IC50 of 210μM.Formula:C17H17NO3SColor and Shape:SolidMolecular weight:315.39FXR agonist 4
FXR agonist 4: EC50 of 1.05μM, treats hyperlipidemia, steatosis, insulin resistance, inflammation in DIO mice, for NAFLD research.Formula:C21H28ClN3OColor and Shape:SolidMolecular weight:373.92RORγt modulator 2
CAS:RORγt modulator 2 is a modulator of retinol-related orphan receptor γt (RORyt) (IC50<50 nM) and can be used in the study of RORγt-mediated diseases such as painFormula:C28H29ClN2O4SColor and Shape:SolidMolecular weight:525.06CK2-IN-6
CAS:CK2-IN-6: Potent CK2 inhibitor for cancer, inflammation, pain, and immune research.Formula:C19H16ClN7O2Color and Shape:SolidMolecular weight:409.83PKR activator 2
CAS:PKR activator 2 is a potent activator of pyruvate kinase-R (PKR).Formula:C18H16N8OSPurity:98%Color and Shape:SolidMolecular weight:392.44IDO-IN-14
CAS:IDO-IN-14 is an IDO inhibitor (IC50: 0.6928 nM).Formula:C23H23ClN4O2Color and Shape:SolidMolecular weight:422.91IDO1-IN-17
CAS:IDO1-IN-17 (I-4) is an IDO1 inhibitor, with an IC 50 of 0.44 μM in hela cells .Formula:C28H32BrClFN5O2Color and Shape:SolidMolecular weight:604.94Carbonic anhydrase inhibitor 13
CAS:Carbonic anhydrase inhibitor 13 (compound 7) is a potent inhibitor of carbonic anhydrase (CA).Formula:C17H15N5O3S2Color and Shape:SolidMolecular weight:401.46hCAIX-IN-6
CAS:6B and 14g inhibit tumor-associated HCA IX with low nanomolar potency; 6K targets HCA XII. All are potential cancer drug leads.Formula:C18H12N2O4SColor and Shape:SolidMolecular weight:352.36Eggmanone
CAS:EGM1: potent PDE4D3 inhibitor, IC50=72 nM, 40-50x selectivity over other PDEs, activates PKA, blocks Hh.Formula:C20H20N2O2S3Color and Shape:SolidMolecular weight:416.58Glucokinase activator 3
CAS:Glucokinase activator 3: potent GK activator, AC50=38 nM, potential for type 2 diabetes research.Formula:C26H33N2O9PS2Color and Shape:SolidMolecular weight:612.65α-Glucosidase-IN-10
CAS:α-Glucosidase-IN-10 (compound 13) is a potent inhibitor of α-glucosidase (IC50: 92.7 μM). α-Glucosidase-IN-10 can be used to study type II diabetes.Formula:C21H15BrN4O2SColor and Shape:SolidMolecular weight:467.34TUPS
CAS:TUPS is a selective soluble epoxide hydrolase inhibitor which protects against isoprenaline-induced cardiac hypertrophy.Formula:C14H18F3N3O4SColor and Shape:SolidMolecular weight:381.37AX 048
CAS:Group IVA cPLA2 inhibitor AX 048 halts arachidonic acid release, preventing prostaglandin production, with XI(50) of 0.022 and ED50 of 1.2 mg/kg.Formula:C22H41NO4Color and Shape:SolidMolecular weight:383.57AMG-7980
CAS:AMG-7980 is a highly specific phosphodiesterase 10A ligand. It shows a good uptake in the striatum.Formula:C19H22N4O2Purity:98%Color and Shape:SolidMolecular weight:338.4MitoTEMPO hydrate
CAS:MitoTEMPO, a mitochondria-targeted antioxidant, scavenges superoxide and alkyl radicals supporting potential therapy for mitochondrial dysfunction.Formula:C29H35N2O2P·Cl·H2OColor and Shape:SolidMolecular weight:528.04sEH inhibitor-14
CAS:sEH inhibitor-14, a benzoxazolone-5-urea analogue, acts as an efficient soluble Epoxide Hydrolase (sEH) inhibitor, demonstrating significant activity with anFormula:C16H12F3N3O4Color and Shape:SoildMolecular weight:367.28Andolast
CAS:Andolast (CR-2039) is an anti-allergic for asthma and COPD, inhibiting IgE synthesis and improving airflow.Formula:C15H11N9OColor and Shape:SolidMolecular weight:333.31JTP-4819
CAS:JTP-4819: potent PEP inhibitor, may treat Alzheimer's, boosts brain peptides and acetylcholine, aiding memory.Formula:C19H25N3O4Color and Shape:SolidMolecular weight:359.42AMG-221
CAS:AMG-221: potent 11β-HSD1 inhibitor, lowers glucose & insulin, reduces obesity in mice.Formula:C14H22N2OSPurity:98%Color and Shape:SolidMolecular weight:266.4Boc-Glu(OBzl)-OSu
CAS:Boc-Glu(OBzl)-OSu can be used for the synthesis of solid phase peptides containing benzyl glutamate residues.Formula:C21H26N2O8Color and Shape:SolidMolecular weight:434.44Sch 34826
CAS:Sch 34826 is a potent, selective neutral endopeptidase inhibitor.Formula:C27H34N2O7Purity:98%Color and Shape:SolidMolecular weight:498.57NPD-1335
CAS:NPD1335: potent TbrPDEB1 inhibitor, submicromolar efficacy, low toxicity, raises cAMP, disrupts cell cycle, kills T. brucei.Formula:C28H29N3O3Purity:98%Color and Shape:SolidMolecular weight:455.55α-Amylase/α-Glucosidase-IN-2
CAS:α-Amylase/α-Glucosidase-IN-2 (compound 5) exhibits strong inhibition activity towards both α-amylase and α-glucosidase enzymes, with IC 50 values of 13.02 μMFormula:C22H16ClN5Color and Shape:SolidMolecular weight:385.85D-threo-PPMP hydrochloride
CAS:D-threo-PPMP inhibits GlyCer synthetase; active enantiomer; reduces MDCK cell growth by 70% at 20 μM.Formula:C29H51ClN2O3Color and Shape:SolidMolecular weight:511.19hCAIX-IN-8
CAS:hCAIX-IN-8, a selective hCAIX inhibitor, IC50: 0.024 μM. Also affects CAII, CAVA (IC50s: 1.99, 1.10 μM), limits cell migration, and induces apoptosis.Formula:C19H16N4O6Color and Shape:SolidMolecular weight:396.35
