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Metabolism

Metabolism

Metabolism inhibitors are compounds that interfere with metabolic pathways, altering the production and utilization of energy within cells. These inhibitors are used to study the regulation of metabolism, the role of metabolic pathways in diseases like cancer and diabetes, and to develop new therapeutic strategies. Metabolism inhibitors can target various enzymes and processes involved in glycolysis, fatty acid oxidation, and other metabolic functions. At CymitQuimica, we offer a wide range of high-quality metabolism inhibitors to support your research in biochemistry, metabolic disorders, and drug development.

Subcategories of "Metabolism"

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Found 8625 products of "Metabolism"

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  • 1a,1b-dihomo Prostaglandin F2α

    CAS:
    <p>1a,1b-Dihomo Prostaglandin F2α (1a,1b-dihomo PGF2α), a hypothetical product of adrenic acid in the COX pathway, is predominantly synthesized in the renal medulla, reflecting the selective distribution of adrenic acid in this region.</p>
    Formula:C22H38O5
    Color and Shape:Solid
    Molecular weight:382.541
  • ICMT-IN-38

    CAS:
    <p>ICMT-IN-38 (Compound 42) is an ICMT inhibitor, demonstrating an IC50 value of 0.049 μM [1].</p>
    Formula:C22H28ClNO
    Color and Shape:Solid
    Molecular weight:357.92
  • IDO-IN-9

    CAS:
    <p>IDO-IN-9 is an indoleamine-2,3-dioxygenase (IDO) inhibitor with IC50s of 0.011 μM (Kinase) and 0.0018 μM (Hela Cell).</p>
    Formula:C13H13BrFN7O3S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:446.25
  • Adibendan

    CAS:
    <p>Adibendan (Adibendanum) is a selective inhibitor of PDE3 with an IC50 of 2.0 μM.</p>
    Formula:C16H14N4O
    Purity:99.52% - >99.99%
    Color and Shape:Solid
    Molecular weight:278.31
  • 2-Myristyldipalmitin

    CAS:
    <p>2-Myristyl dipalmitin (PMP), a triglyceride of palmitic acid, shows potential as a lipid marker for Wilson's disease (WD) [1] [2].</p>
    Formula:C49H94O6
    Color and Shape:Solid
    Molecular weight:779.27
  • 5J-4

    CAS:
    <p>5J-4 is a potent a blocker of calcium release-activated calcium (CRAC) channel and store-operated calcium entry (SOCE).</p>
    Formula:C16H12N2O3S
    Purity:96.12%
    Color and Shape:Solid
    Molecular weight:312.34
  • Benzyl-α-GalNAc

    CAS:
    <p>Benzyl-α-GalNAc (O-glycosylation-IN-1) is a potent inhibitor of O-glycosylation and is used to reduce mucin on cell surfaces.</p>
    Formula:C15H21NO6
    Purity:99.84%
    Color and Shape:Solid
    Molecular weight:311.33
  • 1,2-Dipropionyl-sn-glycero-3-PC

    CAS:
    <p>1,2-Dipropionyl-sn-glycero-3-phosphocholine (PC) is a phospholipid characterized by the presence of propionic acid at its sn-1 and sn-2 positions. This compound has applications in the investigation of interactions between water and the phosphocholine headgroup in aqueous solutions.</p>
    Formula:C14H28NO8P
    Color and Shape:Solid
    Molecular weight:369.4
  • QH536

    CAS:
    <p>QH536 degrades HMGCR (EC50: 0.22 μM), has anti-inflammatory properties, and avoids cholesterol buildup; useful for cardiovascular and NASH research.</p>
    Formula:C33H49N3O3
    Color and Shape:Solid
    Molecular weight:535.76
  • 2-Myristyldistearin

    CAS:
    <p>2-Myristyldistearin (SMS), a triacylglycerol comprising myristic acid and stearic acid [1], showcases its intricate structural composition.</p>
    Formula:C53H102O6
    Color and Shape:Solid
    Molecular weight:835.37
  • Brodimoprim

    CAS:
    <p>Brodimoprim is an inhibitor of dihydrofolate reductase(DHFR).</p>
    Formula:C13H15BrN4O2
    Purity:98% - 98.33%
    Color and Shape:Solid
    Molecular weight:339.19
  • MAGL-IN-6

    CAS:
    <p>MAGL-IN-6, a powerful MAGL blocker, IC50 at 4.71 nM, may assist in neurological disease research.</p>
    Formula:C24H19F3N4O
    Color and Shape:Solid
    Molecular weight:436.43
  • ICMT-IN-3

    CAS:
    <p>ICMT-IN-3 (Compound 27) serves as a potent inhibitor of ICMT, demonstrating an IC50 value of 0.015 μM [1].</p>
    Formula:C22H29NO2
    Color and Shape:Solid
    Molecular weight:339.47
  • ICMT-IN-12

    CAS:
    <p>ICMT-IN-12 (compound 78) serves as an ICMT inhibitor, demonstrating an IC50 value of 0.42 μM [1].</p>
    Formula:C24H33NOS
    Color and Shape:Solid
    Molecular weight:383.59
  • Autotaxin-IN-5

    CAS:
    <p>Autotaxin-IN-5 is an Autotaxin inhibitor. It has the potential to treat idiopathic pulmonary fibrosis.</p>
    Formula:C30H29N9O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:547.61
  • 1-Linoleoyl-3-α-Linolenoyl-rac-glycerol

    CAS:
    <p>1-Linoleoyl-3-α-linolenoyl-rac-glycerol, a diacylglycerol, features linoleic acid at the sn-1 position and α-linolenic acid at the sn-3 position. This compound is identified in olive oil that has undergone lipase-catalyzed glycerolysis, utilizing immobilized lipase B derived from C. antarctica.</p>
    Formula:C39H66O5
    Color and Shape:Solid
    Molecular weight:614.94
  • 1-Myristoyl-2-Palmitoyl-3-Butyryl-rac-glycerol

    CAS:
    <p>1-Myristoyl-2-palmitoyl-3-butyryl-rac-glycerol, a triacylglycerol with myristic acid (at the sn-1 position), palmitic acid (at the sn-2 position), and butyric acid (at the sn-3 position), has been detected in human breast milk.</p>
    Formula:C37H70O6
    Color and Shape:Solid
    Molecular weight:611
  • ATX inhibitor 21

    CAS:
    <p>ATX inhibitor 21 is a potent inhibitor of ATX (IC50: 3490 nM).</p>
    Formula:C26H25F2N5O2S
    Color and Shape:Solid
    Molecular weight:509.57
  • JNJ-40929837

    CAS:
    <p>JNJ-40929837 is an oral inhibitor of LTA4 hydrolase, which catalyzes LTB4 production.</p>
    Formula:C22H24N4O2S
    Color and Shape:Solid
    Molecular weight:408.52
  • cis-13-Octadecenoic Acid

    CAS:
    <p>Cis-13-Octadecenoic acid, a monounsaturated fatty acid, is identified in bovine milk fat.</p>
    Formula:C18H34O2
    Color and Shape:Solid
    Molecular weight:282.46
  • AZD 4017

    CAS:
    <p>AZD 4017 is an inhibitor of 11β-Hydroxysteroid Dehydrogenase Type 1(11β-HSD1) (IC50: 7 nM).</p>
    Formula:C22H33N3O3S
    Purity:99.61%
    Color and Shape:Solid
    Molecular weight:419.58
  • OSMI-2

    CAS:
    <p>OSMI-2 is a cell-permeable inhibitor of O-linked N-acetylglucosamine transferase (OGT).</p>
    Formula:C26H25N3O7S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:555.62
  • ICMT-IN-42

    CAS:
    <p>ICMT-IN-42 (compound 21) serves as an ICMT inhibitor, demonstrating potency with an IC50 of 0.054 μM [1].</p>
    Formula:C23H31NO
    Color and Shape:Solid
    Molecular weight:337.5
  • 6β-hydroxy Testosterone

    CAS:
    <p>6β-hydroxy Testosterone (4-Androsten-6β,17β-diol-3-one) is a 17β-hydroxy steroid, an androgen and endogenous metabolite.</p>
    Formula:C19H28O3
    Color and Shape:Soild
    Molecular weight:304.42
  • (R)-Avanafil

    CAS:
    <p>(R)-Avanafil ((R)-TA1790) is a selective phosphodiesterase type 5 (PDE5) inhibitor with an IC50 of 5.2 nM, utilized for the research of erectile dysfunction [1</p>
    Formula:C23H26ClN7O3
    Color and Shape:Solid
    Molecular weight:483.95
  • ICMT-IN-11

    CAS:
    <p>ICMT-IN-11 (compound 48) serves as an ICMT inhibitor with an IC50 value of 0.031 μM [1].</p>
    Formula:C22H27F2NO2
    Color and Shape:Solid
    Molecular weight:375.45
  • γ-CEHC

    CAS:
    <p>γ-CEHC, a metabolite of γ-tocopherol, is predominantly excreted through urine, primarily in its conjugated form as glucuronide [1], rather than through bile.</p>
    Formula:C15H20O4
    Color and Shape:Solid
    Molecular weight:264.32
  • 1,2-Dipalmitoyl-sn-glycero-3-N,N-dimethyl-PE

    CAS:
    <p>1,2-Dipalmitoyl-sn-glycero-3-N,N-dimethyl-PE is a derivative of 1,2-dipalmitoyl-sn-glycero-3-PE (1,2-DPPE) with two added methyl groups on its sn-3 moiety, which in aqueous suspensions, reduces the phase transition temperature relative to those of 1,2-DPPE and 1,2-dipalmitoyl-sn-glycero-3-N-methyl-PE (1,2-NMeDPPE). It is utilized in creating liposomes and monolayers for investigating membrane permeability and monolayer viscosity.</p>
    Formula:C39H78NO8P
    Color and Shape:Solid
    Molecular weight:720.026
  • SHP2-IN-21

    CAS:
    <p>SHP2-IN-21 (compound 208) is an inhibitor of SHP2, exhibiting an IC50 of 3 nM, and is utilized in glioblastoma research [1].</p>
    Formula:C27H26FN7
    Color and Shape:Solid
    Molecular weight:467.54
  • C16 1-Deoxyceramide (m18:1/16:0)

    CAS:
    <p>C16 1-Deoxyceramide (m18:1/16:0) is a lipid molecule that can be used in life science related research. The CAS number of C16 1-Deoxyceramide (m18:1/16:0) is 1246298-56-5.</p>
    Formula:C34H67NO2
    Color and Shape:Solid
    Molecular weight:521.9
  • HSD17B13-IN-2

    CAS:
    <p>HSD17B13-IN-2 (compound 1) serves as a potent inhibitor of hydroxysteroid 17ß-dehydrogenase 13 (HSD17B13) with demonstrable activity in cellular experiments [1</p>
    Formula:C21H23F2NO4
    Color and Shape:Solid
    Molecular weight:391.41
  • JW 618

    CAS:
    <p>JW 618 is a selective inhibitor of ABHD6, demonstrating inhibition concentrations (IC50 values) of 38 nM for mouse ABHD6 and 13 nM for rat ABHD6, indicating its potent activity across species [1].</p>
    Formula:C17H14F6N2O2
    Color and Shape:Solid
    Molecular weight:392.3
  • PPAR agonist 1

    CAS:
    <p>PPAR agonist 1 is an agonist of PPAR α/γ, used for reducing blood glucose, lipid levels, reducing body weight, and lowering cholesterol.</p>
    Formula:C20H25NO6S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:407.48
  • 14,15-Epoxyeicosatrienoic acid

    CAS:
    <p>14,15-Epoxyeicosatrienoic acid (14,15-EET), derived from Arachidonic acid metabolism, significantly inhibits platelet aggregation in vivo and enhances</p>
    Formula:C20H32O3
    Color and Shape:Solid
    Molecular weight:320.47
  • Glycosidase-IN-1

    CAS:
    <p>Glycosidase-IN-1, a D-mannose-derived inhibitor, has hypoglycemic effects and aids in creating immunosuppressants and β-glucosidase blockers.</p>
    Formula:C13H23NO5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:273.33
  • SR11237

    CAS:
    <p>SR11237 is a Pan retinoid X receptor (RXR) agonist.</p>
    Formula:C24H28O4
    Purity:98.79%
    Color and Shape:Solid
    Molecular weight:380.48
  • ICMT-IN-8

    CAS:
    <p>ICMT-IN-8 (compound 30) serves as an inhibitor of ICMT, exhibiting an IC50 value of 0.652 μM [1].</p>
    Formula:C23H31NO3
    Color and Shape:Solid
    Molecular weight:369.5
  • GLUT4 activator 1

    CAS:
    <p>GLUT4 activator 1 is a potent glucose transporter type 4 (GLUT4) translocation activator (EC50: 0.14 μM).</p>
    Formula:C23H21FN4O3S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:452.5
  • (R)-Palmitoyl-(2-methyl)ethanolamide

    CAS:
    <p>(R)-Palmitoyl-(2-methyl)ethanolamide (Me-PEA) acts as a competitive inhibitor against [3H]-AEA metabolism, exhibiting a K i value of 6.6 μM [1].</p>
    Formula:C19H39NO2
    Color and Shape:Solid
    Molecular weight:313.526
  • Dendrogenin A

    CAS:
    <p>Dendrogenin A (DDA) is a compound acting as a selective liver X receptor (LXR) modulator, cholesterol epoxide hydrolase inhibitor (Ki = 120 nM), and a metabolic</p>
    Formula:C32H55N3O2
    Color and Shape:Solid
    Molecular weight:513.80
  • DPM-1001 trihydrochloride


    <p>DPM-1001 trihydrochloride: Potent PTP1B inhibitor, IC50 100 nM, oral, non-competitive, anti-diabetic.</p>
    Formula:C35H60Cl3N3O3
    Color and Shape:Solid
    Molecular weight:677.23
  • CM-10-18

    CAS:
    <p>CM-10-18: potent ER α-glucosidase inhibitor, strong antiviral against hemorrhagic fever viruses, protects mice from dengue fatality.</p>
    Formula:C17H35NO5
    Color and Shape:Solid
    Molecular weight:333.46
  • Glyoxalase I inhibitor 3

    CAS:
    <p>Compound 22g: potent GLO1 inhibitor; IC50=0.011 μM; potential for depression, anxiety research.</p>
    Formula:C22H21N3O3
    Color and Shape:Solid
    Molecular weight:375.42
  • Glucosamine Cholesterol

    CAS:
    <p>Glucosamine Cholesterol, also known as N-Cholesteryl succinyl glucosamine, is a lipid conjugate derived from glucosamine. It plays a crucial role in the development of lipid nanoparticles (LNPs) [1].</p>
    Formula:C37H61NO8
    Color and Shape:Solid
    Molecular weight:647.88
  • C82

    CAS:
    <p>C82 acts as an inhibitor of Mycobacterium tuberculosis (Mtb) cyclic dinucleotide phosphodiesterase (CdnP), with an IC50 value of 17.5 µM. This particular enzyme is responsible for breaking down cyclic di-AMP (c-di-AMP) into adenosine 5'-monophosphate (AMP). Notably, C82 demonstrates selectivity for Mtb CdnP over other bacterial cyclic dinucleotide phosphodiesterases (CDN PDEs) such as Yybt, RocR, and Group B Streptococcus (GBS) CdnP, as well as the mammalian CDN PDE ENPP1, and the viral CDN PDE poxin, showing effectiveness at a concentration of 200 µM.</p>
    Formula:C17H17N3O3S
    Color and Shape:Solid
    Molecular weight:343.4
  • Temocaprilat

    CAS:
    <p>Temocaprilat (RS5139) is an Angiotensin-converting Enzyme (ACE) inhibitor.</p>
    Formula:C21H24N2O5S2
    Purity:99.31%
    Color and Shape:White To Off-White Solid
    Molecular weight:448.56
  • GIV3727

    CAS:
    <p>GIV3727, a bitter taste receptor hTAS2R antagonist, inhibits the activation of hTAS2R31 by saccharin and acesulfame potassium, effectively diminishing the</p>
    Formula:C12H22O2
    Color and Shape:Solid
    Molecular weight:198.3
  • h-NTPDase-IN-5

    CAS:
    <p>h-NTPDase-IN-5 (compound 3b) serves as a pan-inhibitor of NTPDase, exhibiting inhibitory concentration 50 (IC50) values of 1.10 μM (h-NTPDase1), 44.73 μM (h-</p>
    Formula:C23H21N3O2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:403.5
  • Monohydroxy Melphalan hydrochloride

    CAS:
    <p>Monohydroxy melphalan, a degradation product and DNA alkylating agent derived from melphalan, results from melphalan hydrolysis in aqueous solutions such as cell culture medium and human plasma. It enhances DNA adducts in ML-1 myeloblastic leukemia cells based on concentration and induces cytotoxicity with an IC50 value of 28.1 μg/ml.</p>
    Formula:C13H19ClN2O3HCl
    Color and Shape:Solid
    Molecular weight:359.68
  • FXa-IN-1

    CAS:
    <p>FXa-IN-1, an FXa blocker: IC50=3 nM, Ki=0.7 nM, orally available, long half-life, for thrombosis research.</p>
    Formula:C24H18F5N5O
    Color and Shape:Solid
    Molecular weight:487.42