Metabolism
Metabolism inhibitors are compounds that interfere with metabolic pathways, altering the production and utilization of energy within cells. These inhibitors are used to study the regulation of metabolism, the role of metabolic pathways in diseases like cancer and diabetes, and to develop new therapeutic strategies. Metabolism inhibitors can target various enzymes and processes involved in glycolysis, fatty acid oxidation, and other metabolic functions. At CymitQuimica, we offer a wide range of high-quality metabolism inhibitors to support your research in biochemistry, metabolic disorders, and drug development.
Subcategories of "Metabolism"
- AhR(41 products)
- Aminopeptidase(67 products)
- CETP(18 products)
- Carbonic Anhydrase(178 products)
- Casein Kinase(130 products)
- DHFR(33 products)
- Decarboxylase(4 products)
- Dehydrogenase(269 products)
- FAAH(64 products)
- FXR(58 products)
- Factor Xa(80 products)
- Fatty Acid Synthase(32 products)
- Ferroptosis(215 products)
- GR(3 products)
- GSNOR(3 products)
- Glucokinase(54 products)
- HIF/HIF Prolyl-Hydroxylase(142 products)
- HMG-CoA Reductase(33 products)
- Hydroxylase(30 products)
- IDO(82 products)
- LDL(8 products)
- Lipase(97 products)
- Lipid(59 products)
- Lipoxygenase(124 products)
- MAO(87 products)
- MPO(2 products)
- NAMPT(36 products)
- P450(6 products)
- PAI-1(25 products)
- PDE(166 products)
- PED(1 products)
- PKM(15 products)
- PPAR(164 products)
- Phospholipase(82 products)
- ROR(42 products)
- Retinoid Receptor(29 products)
- SGK(11 products)
- Thioredoxin(12 products)
- Transferase(30 products)
- Transporter(42 products)
- UGT(4 products)
- Xanthine Oxidase (XO) Inhibitors(9 products)
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Found 8626 products of "Metabolism"
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FR-190809
CAS:<p>FR-190809 is a nonadrenotoxic and orally efficacious inhibitor of acyl-CoA:cholesterol O-acyltransferase (ACAT) (IC50: 45 nM).</p>Formula:C29H34FN3O6S2Purity:98%Color and Shape:SolidMolecular weight:603.73Edaglitazone
CAS:<p>Edaglitazone (R-483) is a PPARγ agonist with antiplatelet activity that can be used in studies of diabetes and obesity.</p>Formula:C24H20N2O4S2Purity:98%Color and Shape:SolidMolecular weight:464.56S-Benzylglutathione
CAS:<p>S-Benzylglutathione acts as a competitive inhibitor of glutathionase and undergoes conversion by rat kidney microsomes into its cysteine derivatives.</p>Formula:C17H23N3O6SColor and Shape:SolidMolecular weight:397.45ZK824190
CAS:<p>ZK824190: oral uPA inhibitor, IC50 - uPA 237 nM, tPA 1600 nM, Plasmin 1850 nM.</p>Formula:C22H20F2N2O4Purity:98.84%Color and Shape:SolidMolecular weight:414.4Me-Indoxam
CAS:<p>Me-Indoxam is an inhibitor of sPLA2. It has no effect on arachidonic acid release and platelet activating factor synthesis.</p>Formula:C26H22N2O5Purity:98%Color and Shape:SolidMolecular weight:442.467,7-Dimethyl-(5Z,8Z)-eicosadienoic acid
CAS:<p>7,7-Dimethyl-(5Z,8Z)-eicosadienoic acid (DEDA, 5 μM) significantly impacts the response to βA(25-35) stimulation. It reduces the formation of ROS.</p>Formula:C22H40O2Color and Shape:SolidMolecular weight:336.55DHODH-IN-22
CAS:<p>DHODH-IN-22: potent, selective DHODH inhibitor, orally active, IC50: 0.3 nM, for AML research.</p>Formula:C21H21ClF4N6O5Color and Shape:SolidMolecular weight:548.88JGB-1-155
CAS:<p>JGB-1-155, serving as a positive allosteric modulator (N-PAMs), effectively enhances the activity of nicotinamide phosphoribosyltransferase (NAMPT) with an EC 50 of 3.29 μM. It mitigates oxidative stress by elevating NAD+ levels in THP-1 human monocytes and reduces TNFα-induced reactive oxygen species (ROS) in HT-22 cells [1].</p>Formula:C26H38N2O3Color and Shape:SolidMolecular weight:426.59(+/-)12-HpETE
CAS:<p>(+/-)12-HpETE, a vasodilator, is a 12-hydroxyicosatetraenoic acid produced by lipoxygenase [1].</p>Formula:C20H32O4Color and Shape:SolidMolecular weight:336.479(Z),11(E),13(Z)-Octadecatrienoic Acid methyl ester
CAS:<p>9(Z),11(E),13(Z)-Octadecatrienoic acid methyl ester, an isomer of 9(Z),11(E),13(E)-octadecatrienoic acid methyl ester and the methyl ester derivative of 9(Z),11(E),13(Z)-octadecatrienoic acid, serves as a standard for quantifying 9(Z),11(E),13(Z)-octadecatrienoic acid in wild growing pomegranate (P. granatum) seed oil [Matreya, LLC. Catalog No. 1240].</p>Formula:C19H32O2Color and Shape:SolidMolecular weight:292.46IDO1/2-IN-1
CAS:<p>First potent oral dual IDO1/IDO2 inhibitor with antitumor properties; IC50: 28 nM (IDO1), 144 nM (IDO2).</p>Formula:C16H18BrFN8O4Color and Shape:SolidMolecular weight:485.27Prostaglandin F2α-1-glyceryl ester
CAS:<p>Prostaglandin F2α-1-glyceryl ester undergoes oxidation via 15-hydroxyprostaglandin dehydrogenase (15-HPGDH) [1].</p>Formula:C23H40O7Color and Shape:SolidMolecular weight:428.566Bemoradan
CAS:<p>Bemoradan is an inhibitor of the rolipram-insensitive cyclic AMP phosphodiesterase from canine heart tissue</p>Formula:C13H13N3O3Color and Shape:SolidMolecular weight:259.26KCA-1490
CAS:<p>KCA-1490 is an inhibitor of dual PDE3/4.</p>Formula:C14H13F3N4O2Purity:98%Color and Shape:SolidMolecular weight:326.27PPARδ agonist 9
CAS:<p>PPARδ agonist 9 (compound 21), with an EC50 of 3.6 nM, is effective in vivo, decreasing serum MCP-1 concentrations in mice and markedly reducing atherosclerotic</p>Formula:C26H28ClF3N4O3SPurity:98%Color and Shape:SolidMolecular weight:569.04Dieicosanoin
CAS:<p>Dieicosanoin is a diacylglycerol that incorporates arachidic acid, a saturated long-chain fatty acid featuring a 20-carbon backbone. This acid is derivable from sources such as peanut butter and anaerobic fungi [1] [2].</p>Formula:C43H84O5Color and Shape:SolidMolecular weight:681.12 (Monomer)CJ-463
CAS:<p>CJ-463, a selective uPA blocker, shows strong anti-tumor effect, especially at 100mg/kg, potentially treating lung cancer.</p>Formula:C21H27N5O6SColor and Shape:SolidMolecular weight:477.53Yonkenafil HCl
CAS:<p>Yonkenafil HCl, a PDE5 inhibitor, is used potentially for the treatment of erectile dysfunction.</p>Formula:C24H34ClN5O4SColor and Shape:SolidMolecular weight:524.088(Z),14(Z)-Eicosadienoic Acid
CAS:<p>8(Z),14(Z)-Eicosadienoic Acid, an ω-8 C20:2 fatty acid, constitutes 0.19% of total fatty acids in human milk. In vivo, it is converted by desaturases into eicosatrienoic acids, known for their potent vasodilator properties. However, the physiological effects of 8(Z),14(Z)-Eicosadienoic Acid remain unexplored.</p>Formula:C20H36O2Color and Shape:SolidMolecular weight:308.506(Rac)-Lonafarnib
CAS:<p>(Rac)-Lonafarnib is a racemic FTase inhibitor, effective against H-ras, K-ras, N-ras (IC50: 1.9, 5.2, 2.8 nM), and has anti-HDV properties.</p>Formula:C27H31Br2ClN4O2Color and Shape:SolidMolecular weight:638.821a,1b-dihomo Prostaglandin F2α
CAS:<p>1a,1b-Dihomo Prostaglandin F2α (1a,1b-dihomo PGF2α), a hypothetical product of adrenic acid in the COX pathway, is predominantly synthesized in the renal medulla, reflecting the selective distribution of adrenic acid in this region.</p>Formula:C22H38O5Color and Shape:SolidMolecular weight:382.5411-Isopropyltryptophan
CAS:<p>1-Isopropyltryptophan (1-IsoPT), an IDO1 inhibitor, suppresses the expression of IDO-1 and IDO-2 mRNA induced by IFN-γ stimulation [1].</p>Formula:C14H18N2O2Purity:98%Color and Shape:SolidMolecular weight:246.3LY-311727
CAS:<p>secreted phospholipase A2 (sPLA2) inhibitor</p>Formula:C22H27N2O5PPurity:98%Color and Shape:SolidMolecular weight:430.43Metformin hydroxy analog 2
CAS:<p>Metformin hydroxy analog 2, an oxidation product of the biguanide metformin (1), represents a chemically transformed variant of the original compound, showcasing a modified molecular structure through the process of oxidation.</p>Formula:C4H10N4OColor and Shape:SolidMolecular weight:130.15α-Glucosidase-IN-11
CAS:<p>α-Glucosidase-IN-11 is a highly permeable competitive inhibitor of α-glucosidase (IC50: 0.56 μM).</p>Formula:C23H20N2O6Color and Shape:SolidMolecular weight:420.41PHD-IN-1
CAS:<p>PHD-IN-1 (compound 80) serves as a potent PHD2 inhibitor, exhibiting an IC50 value of ≤5 nM.</p>Formula:C24H23N7O2Purity:98%Color and Shape:SolidMolecular weight:441.496β-hydroxy Testosterone
CAS:<p>6β-hydroxy Testosterone （4-Androsten-6β,17β-diol-3-one） is a 17β-hydroxy steroid, an androgen and endogenous metabolite.</p>Formula:C19H28O3Color and Shape:SoildMolecular weight:304.42Adibendan
CAS:<p>Adibendan (Adibendanum) is a selective inhibitor of PDE3 with an IC50 of 2.0 μM.</p>Formula:C16H14N4OPurity:99.52% - >99.99%Color and Shape:SolidMolecular weight:278.31IDO1/TDO-IN-6
CAS:<p>IDO1/TDO-IN-6 (compound 11) is a dual inhibitor targeting IDO1 and TDO, exhibiting IC50 values of 2.25 μM for IDO1 and 2.89 μM for TDO.</p>Formula:C20H17NO5Purity:98%Color and Shape:SolidMolecular weight:351.35PDE5-IN-42
CAS:<p>PDE5-IN-42 is a selective inhibitor of second-generation phosphodiesterase type 5 (PDE5).</p>Formula:C23H31N7O3Purity:98%Color and Shape:SolidMolecular weight:453.54sEH/AChE-IN-4
CAS:<p>sEH/AChE-IN-4-15 is a dual sEH and AChE inhibitor crossing the BBB, with IC50s: 3.1 nM (hsEH), 1660 nM (hAChE), 179 nM (hBChE), 14.5 nM (msEH), 102 nM (mAChE).</p>Formula:C35H39ClF3N5O3Color and Shape:SolidMolecular weight:670.16L-690488
CAS:<p>L-690488 has more effective cell penetration than L-690330. L-690488 is a prodrug of L-690330 and is a selective inositol monophosphatase (IMPase) inhibitor.</p>Formula:C32H52O16P2Purity:98%Color and Shape:SolidMolecular weight:754.69ICMT-IN-44
CAS:<p>ICMT-IN-44 (compound 23) serves as an ICMT inhibitor with an IC50 value of 0.167 μM [1].</p>Formula:C24H33NOColor and Shape:SolidMolecular weight:351.52Siguazodan
CAS:<p>Siguazodan (SKF 94836) is an effective, selective, orally active phosphodiesterase III ((PDE-III)) inhibitor with an IC50 of 117 nM.</p>Formula:C14H16N6OPurity:99.62% - 99.87%Color and Shape:SolidMolecular weight:284.32ATX inhibitor 15
CAS:<p>ATX inhibitor 15, an indole-based carbamate, has a 2.17 nM IC50 against ATX, suppresses pro-fibrotic genes, and protects against mouse lung fibrosis.</p>Formula:C27H32ClN5O4SColor and Shape:SolidMolecular weight:558.09CoPoP
CAS:<p>CoPoP, a liposome-based vaccine adjuvant, holds potential for application in cancer research [1].</p>Formula:C57H80CoN5O9PColor and Shape:SolidMolecular weight:1069.18Mitochondria degrader-1
CAS:<p>Mitochondria degrader-1, a potent autophagy inducer, aids in neurodegenerative, cancer, and aging disease research.</p>Formula:C33H49ClFN7O8SColor and Shape:SolidMolecular weight:758.3ICMT-IN-1
CAS:<p>ICMT-IN-1 (compound 75) is a potent ICMT inhibitor with an IC50 value of 0.0013 μM.</p>Formula:C24H33NO2Color and Shape:SolidMolecular weight:367.52Tetrahydro-11-dehydrocorticosterone
CAS:<p>Tetrahydro-11-dehydrocorticosterone is an inhibitor of 11β-hydroxysteroid dehydrogenase [1].</p>Formula:C21H32O4Color and Shape:SolidMolecular weight:348.48PF-04937319
CAS:<p>PF-04937319 activates glucokinase (EC50=154.4μM) with low hypoglycemia risk, researched for type 2 diabetes treatment.</p>Formula:C22H20N6O4Purity:99.89%Color and Shape:SolidMolecular weight:432.43Monohydroxy Melphalan hydrochloride
CAS:<p>Monohydroxy melphalan, a degradation product and DNA alkylating agent derived from melphalan, results from melphalan hydrolysis in aqueous solutions such as cell culture medium and human plasma. It enhances DNA adducts in ML-1 myeloblastic leukemia cells based on concentration and induces cytotoxicity with an IC50 value of 28.1 μg/ml.</p>Formula:C13H19ClN2O3HClColor and Shape:SolidMolecular weight:359.68CM-10-18
CAS:<p>CM-10-18: potent ER α-glucosidase inhibitor, strong antiviral against hemorrhagic fever viruses, protects mice from dengue fatality.</p>Formula:C17H35NO5Color and Shape:SolidMolecular weight:333.46ALP/Carbonic anhydrase-IN-1
CAS:<p>Compound 1e, also known as ALP/Carbonic anhydrase-IN-1, is a dual inhibitor targeting both carbonic anhydrase (CA) isozymes II, IX, and XII, as well as alkaline</p>Formula:C15H16N2Purity:98%Color and Shape:SolidMolecular weight:224.3Inz-1
CAS:<p>Inz-1 is an effective and fungal-selective inhibitor of mitochondrial cytochrome bc1 with IC50s of 8.092 and 45.320 μM for yeast and human.</p>Formula:C16H14N2O2Purity:99.55% - 99.88%Color and Shape:SolidMolecular weight:266.29HSD17B13-IN-3
CAS:<p>HSD17B13-IN-3 (compound 2) is a potent inhibitor of hydroxysteroid 17ß-dehydrogenase 13 (HSD17B13), lacking cellular experimental activity [1].</p>Formula:C22H21NO6S2Color and Shape:SolidMolecular weight:459.54H-0106 Dihydrochloride
CAS:<p>H-0106 Dihydrochloride is an inhibitor of ROCK that acts by applying strong intraocular pressure (IOP)-lowering effects into the eyes of monkeys.</p>Formula:C16H22Cl3N3O2SPurity:98%Color and Shape:SolidMolecular weight:426.791-Deazaadenosine
CAS:<p>1-Deazaadenosine, an adenosine deaminase inhibitor (Ki: 0.66 μM), may treat cancer, particularly lymphoproliferative disorders.</p>Formula:C11H14N4O4Purity:98%Color and Shape:SolidMolecular weight:266.25ICMT-IN-19
CAS:<p>ICMT-IN-19 (compound 53) serves as a potent inhibitor of ICMT, demonstrating an IC50 value of 0.026 μM [1].</p>Formula:C21H26N2O3Color and Shape:SolidMolecular weight:354.44ICMT-IN-46
CAS:<p>ICMT-IN-46 (compound 25) is a potent inhibitor of isoprenylcysteine carboxyl methyltransferase (ICMT), exhibiting an IC50 value of 0.556 μM [1].</p>Formula:C25H35NOColor and Shape:SolidMolecular weight:365.55Tetramyristoylcardiolipin
CAS:<p>Tetramyristoylcardiolipin (TMCL), an anionic lipid, plays a crucial role in studying cell membrane function and drug delivery mechanisms [1].</p>Formula:C65H132N2O17P2Color and Shape:SolidMolecular weight:1275.69
