Metabolism
Metabolism inhibitors are compounds that interfere with metabolic pathways, altering the production and utilization of energy within cells. These inhibitors are used to study the regulation of metabolism, the role of metabolic pathways in diseases like cancer and diabetes, and to develop new therapeutic strategies. Metabolism inhibitors can target various enzymes and processes involved in glycolysis, fatty acid oxidation, and other metabolic functions. At CymitQuimica, we offer a wide range of high-quality metabolism inhibitors to support your research in biochemistry, metabolic disorders, and drug development.
Subcategories of "Metabolism"
- AhR(41 products)
- Aminopeptidase(67 products)
- CETP(18 products)
- Carbonic Anhydrase(178 products)
- Casein Kinase(130 products)
- DHFR(33 products)
- Decarboxylase(4 products)
- Dehydrogenase(270 products)
- FAAH(64 products)
- FXR(58 products)
- Factor Xa(80 products)
- Fatty Acid Synthase(33 products)
- Ferroptosis(215 products)
- GR(3 products)
- GSNOR(3 products)
- Glucokinase(54 products)
- HIF/HIF Prolyl-Hydroxylase(142 products)
- HMG-CoA Reductase(33 products)
- Hydroxylase(30 products)
- IDO(82 products)
- LDL(8 products)
- Lipase(97 products)
- Lipid(59 products)
- Lipoxygenase(125 products)
- MAO(87 products)
- MPO(2 products)
- NAMPT(36 products)
- P450(6 products)
- PAI-1(25 products)
- PDE(166 products)
- PED(1 products)
- PKM(15 products)
- PPAR(164 products)
- Phospholipase(82 products)
- ROR(42 products)
- Retinoid Receptor(29 products)
- SGK(11 products)
- Thioredoxin(12 products)
- Transferase(30 products)
- Transporter(42 products)
- UGT(4 products)
- Xanthine Oxidase (XO) Inhibitors(9 products)
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Found 8625 products of "Metabolism"
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Acyl coenzyme A synthetase
CAS:<p>ACS activates fatty acids for lipid metabolism and the TCA cycle.</p>Color and Shape:Solid1,2-Dilinoleoyl-sn-glycerol
CAS:<p>1,2-Dilinoleoyl-sn-glycerol, a DAG with two linoleic acids, is in rat liver, spinach membranes, and indicates preeclampsia risk in pregnancy.</p>Formula:C39H68O5Color and Shape:SolidMolecular weight:616.95CB1151
CAS:<p>CB1151 is a 20-epi analogue of 1,25 dihydroxyvitamin D3 with anti-tumor effects. It inhibits MCF-7 cell growth (IC50: 0.82 nM).</p>Formula:C28H46O4Purity:98%Color and Shape:SolidMolecular weight:446.66Andrastin A
CAS:<p>Andrastin A is a useful organic compound for research related to life sciences. The catalog number is T125574 and the CAS number is 174232-42-9.</p>Formula:C28H38O7Color and Shape:SolidMolecular weight:486.605hCAII-IN-7
<p>hCAII-IN-7 (R-13) inhibits human CA I, II, IV, IX with K i of 60.7, 320.7, 2298, 35.2 nM respectively.</p>Formula:C20H25N3O4SColor and Shape:SolidMolecular weight:403.5Monaschromone
CAS:<p>Monaschromone, a polyketide, hinders B. cinerea, A. solani, M. oryzae, G. saubinettii growth; MICs 6.25-12.5 μM.</p>Formula:C11H12O4Color and Shape:SolidMolecular weight:208.21D-Glyceric acid
CAS:<p>D-Glyceric acid, found in urine, aids in Primary hyperoxaluria I & Glutaric Acidemia II research.</p>Formula:C3H6O4Color and Shape:SolidMolecular weight:106.08Glucose 6-phosphate isomerase
CAS:<p>GPI, also PGI or PHI, is a conserved dimeric glycolytic enzyme, catalyzing glucose-6-phosphate to fructose-6-phosphate isomerization.</p>Color and Shape:Solid(E,Z)-2-propyl-2-Pentenoic Acid
CAS:<p>(E,Z)-2-propyl-2-Pentenoic acid, a valproic acid metabolite, matches its anticonvulsant effects without teratogenicity or hepatotoxicity.</p>Formula:C8H14O2Color and Shape:SolidMolecular weight:142.23α-Akebonoic Acid
CAS:<p>3α-Akebonoic acid is a natural product isolated from Holboellia coriacea Diels with antitumor activity.</p>Formula:C29H44O3Color and Shape:SolidMolecular weight:440.67Cortisol sulfate sodium
CAS:<p>Cortisol sulfate sodium, a Cortisol metabolite, binds specifically to intracellular transcortin.</p>Formula:C21H29NaO8SColor and Shape:SolidMolecular weight:464.51Glycerol phosphate dehydrogenase
CAS:<p>Glycerol phosphate dehydrogenase catalyzes the conversion of dihydroxyacetone phosphate to α-glycerol phosphate [1] .</p>Color and Shape:SolidCalcineurin Autoinhibitory Peptide
CAS:<p>Selective inhibitor of Ca2+-calmodulin-dependent protein phosphatase (calcineurin) (IC50 ~ 10 μM). Does not inhibit PP1, PP2A or CaM kinase II (IC50 > 100 mM).</p>Formula:C124H205N39O39S2Purity:98%Color and Shape:SolidMolecular weight:2930.34Z-Pro-prolinal
CAS:<p>Z-Pro-prolinal, an orally active PREP inhibitor, IC50: 0.4 nM in porcine.</p>Formula:C18H22N2O4Color and Shape:SolidMolecular weight:330.38Pheleuin
CAS:<p>Pheleuin, an untested pyrazinone derivative from a dipeptide aldehyde, may inhibit calpain or affect S. aureus virulence.</p>Formula:C15H18N2OColor and Shape:SolidMolecular weight:242.32CTL-06
<p>CTL-06, a Fatty Acid Synthase (FASN) inhibitor with an IC50 of 3 μM, induces apoptosis, while CTL-12 impedes cell cycle progression in the Sub-G1/S phase and</p>Formula:C21H21ClN4O4Color and Shape:SolidMolecular weight:428.87Folipastatin
CAS:<p>Folipastatin is a useful organic compound for research related to life sciences. The catalog number is T125927 and the CAS number is 139959-71-0.</p>Formula:C23H24O5Color and Shape:SolidMolecular weight:380.44h-NTPDase-IN-4
CAS:<p>h-NTPDase-IN-4, a pan-inhibitor, targets h-NTPDase1/2/3/8 with IC50s: 3.58, 10.21, 0.13, 13.57 μM.</p>Formula:C22H8F12N2SPurity:99.92%Color and Shape:SoildMolecular weight:560.362-Chlorophenylboronic acid
CAS:<p>2-Chlorophenylboronic acid: A monohalogenated phenylboronic acid used in drug synthesis and as a fatty acid amidase inhibitor.</p>Formula:C6H6BClO2Purity:99.42%Color and Shape:SolidMolecular weight:156.37(Z)-2-Octenoic acid
CAS:<p>Z-2-Octenoic acid, the Z-isomer of 2-Octenoic acid, is also known as trans-2-Octenoic acid and serves as a metabolite in Mucor species.</p>Formula:C8H14O2Color and Shape:SolidMolecular weight:142.20β-Tetralone
CAS:<p>β-Tetralone (2-Tetralone) is a vital drug synthesis precursor with complex pharmacological properties in combating neurological disorders. Cost-effective and quality-assured.</p>Formula:C10H10OPurity:97.26% - 99.18%Color and Shape:Clear To Yellow LiquidMolecular weight:146.19Adenosine 5'-succinate
CAS:<p>Adenosine 5'-succinate, similar to AMP, inhibits taste receptors activated by Denatonium.</p>Formula:C14H17N5O7Color and Shape:SolidMolecular weight:367.318Ilexoside O
CAS:<p>Ilexoside O, a root-derived triterpene saponin, modestly blocks XOD with an IC50 of 53.05 μM.</p>Formula:C53H86O22Color and Shape:SolidMolecular weight:1075.249H-Gly-Pro-Gly-NH2
CAS:<p>H-Gly-Pro-Gly-NH2, a tripeptide, inhibits HIV-1 and HIV-2 replication (EC50: 35µM, 30µM) by blocking capsid formation.</p>Formula:C9H16N4O3Color and Shape:SolidMolecular weight:228.25L-Lactic acid-13C3
CAS:<p>L-Lactic acid-13C3 is a stable isotope labeled L-Lactic acid analog. L-Lactic acid-13C3 can be used for lactate metabolism research.</p>Formula:C3H6O3Color and Shape:SolidMolecular weight:93.055PROTAC CYP1B1 degrader-2
CAS:<p>PROTAC CYP1B1 degrader-2 (compound PV2), a VHL (von Hippel - Landau) E3 ligase-based degrader of CYP1B1, exhibits a DC50 of 1.0 nM after 24 hours in A549/Taxol cells. Furthermore, it effectively inhibits the growth, migration, and invasion of A549/Taxol cells.</p>Formula:C49H56ClN7O5S3Color and Shape:SolidMolecular weight:954.66BAY-277
<p>BAY-277 is a degrader of METAP2, with IC50 values of 5.8 nM for human METAP2 (hMETAP2) and 5.9 nM for mouse METAP2 (mMETAP2).</p>Formula:C44H52N8O5Color and Shape:SolidMolecular weight:772.93Fmoc-Ile-Ser(psi(Me,Me)pro)-OH
CAS:<p>Fmoc-Ile-Ser(psi(Me,Me)pro)-OH is a dipeptide.</p>Formula:C27H32N2O6Color and Shape:SolidMolecular weight:480.55BTT-266
CAS:<p>BTT-266 is a blocker of voltage-gated calcium channel for pain management.</p>Formula:C34H28N4O4Purity:98.34%Color and Shape:SolidMolecular weight:556.61Fmoc-Gly-Ser(psi(Me,Me)pro)-OH
CAS:<p>Fmoc-Gly-Ser(psi(Me,Me)pro)-OH is a dipeptide.</p>Formula:C23H24N2O6Color and Shape:SolidMolecular weight:424.45KT-362 free base
CAS:<p>KT-362 is a calcium channel blocker with antihypertensive properties that can be used in the study of cardiovascular disease.</p>Formula:C22H28N2O3SPurity:99.76%Color and Shape:SoildMolecular weight:400.5311β-HSD1 inibitor 17
CAS:<p>11β-HSD1 inibitor 17 is an inhibitor of 11β-hydroxysteroid dehydrogenase (11β-HSD1).</p>Formula:C22H20F3N3O2SPurity:99.26% - 99.72%Color and Shape:SoildMolecular weight:447.47Dimethylaminomicheliolide HCl
CAS:<p>Dimethylaminomicheliolide HCl has potential anti-inflammatory and anti-tumor activity and inhibits the proliferation of glioblastoma cells by targeting pyruvate</p>Formula:C17H28ClNO3Purity:99.55%Color and Shape:SoildMolecular weight:329.86Octanoyl Coenzyme A (sodium salt)
<p>Octanoyl Coenzyme A (sodium salt) inhibits citrate synthase and glutamate dehydrogenase with an IC50 of 0.4–1.6 mM.</p>Formula:C29H49N7NaO17P3SColor and Shape:SolidMolecular weight:915.71Ethyl gentisate
CAS:<p>Ethyl gentisate acts as a dual regulator of cell differentiation, promoting osteoblast differentiation while inhibiting osteoclast differentiation.</p>Formula:C9H10O4Purity:99.55%Color and Shape:SolidMolecular weight:182.172,7"-Phloroglucinol-6,6'-bieckol
CAS:<p>2,7"-Phloroglucinol-6,6'-bieckol serves as an effective oral dual α-amylase/α-glucosidase inhibitor, demonstrating IC 50 concentrations of 6.94 μM and 23.35 μM, respectively. This compound is beneficial in mitigating postprandial hyperglycemia among diabetic mice and is applicable in diabetes research [1].</p>Formula:C48H30O23Color and Shape:SolidMolecular weight:974.74hCES2A-IN-2
hCES2A-IN-2 (compound 14n) is an orally active, highly specific, irreversible, covalent inhibitor of hCES2A with an IC50 of 0.04 nM. It targets and covalently binds to the catalytic serine residue (Ser-228) of hCES2A. hCES2A-IN-2 can significantly mitigate irinotecan-induced gastrointestinal toxicity (ITGT) without diminishing the antitumor efficacy of irinotecan in tumor-bearing mice.Color and Shape:Odour SolidUG-480
<p>UG-480 is a Gemini analog that effectively stabilizes the active VDR conformation. It exhibits antiproliferative effects in estrogen receptor-positive MCF-7 breast adenocarcinoma cells and is utilized in cancer research.</p>Color and Shape:Odour SolidH-Met-Val-OH
CAS:<p>H-Met-Val-OH is a dipeptide inhibiting FMO1 and FMO3 and promoting neurite outgrowth, relevant for neuroregenerative and enzymatic modulation studies.</p>Formula:C10H20N2O3SColor and Shape:SolidMolecular weight:248.34D-Threonine
CAS:<p>D-Threonine (H-D-Thr-OH) is one of the metabolites of Saccharomyces cerevisiae.</p>Formula:C4H9NO3Purity:≥98%Color and Shape:SolidMolecular weight:119.12FZQ-21
<p>FZQ-21 (Compound 70P) is an inhibitor of the water-soluble epoxide hydrolase (sEH), with an IC50 value of 4 nM. The IC50 for inhibiting human sEH is 1.5 nM, which is comparable to that of EC5026 (1.7 nM). FZQ-21 is utilized in sepsis research.</p>Formula:C28H30N4O3Molecular weight:470.23179FABP4-IN-3
<p>FABP4-IN-3 (Compound C3) is a highly selective inhibitor of FABP4, with an inhibition constant (Ki) of 25 ± 3 nM for FABP4 and a Ki of 15.03 μM for FABP3, showcasing a selectivity factor of 601 times over FABP3. It also demonstrates metabolic stability and potent anti-inflammatory activity in cells, making it a promising candidate for research in metabolic disorders, cardiac dysfunction, and inflammation-related diseases.</p>Formula:C20H16ClNO2Molecular weight:337.08696Photo-DL-lysine
<p>Photo-DL-lysine is a photo-reactive amino acid based on DL-lysine used to capture proteins that are post-translationally modified by lysine binding.</p>Formula:C6H12N4O2Molecular weight:172.09603Transketolase-IN-5
<p>Transketolase-IN-5 (compound 6ba) is an inhibitor of transketolase. It exhibits herbicidal activity against Amaranthus retroflexus, Setaria viridis, and Digitaria sanguinalis.</p>Formula:C20H24ClN5OMolecular weight:385.16694Xanthine oxidase-IN-13
<p>Xanthine oxidase-IN-13 (Compound 10) is a selective inhibitor of xanthine oxidase, with an IC50 of 149.56 μM for bovine xanthine oxidase. It is utilized in the study of inflammatory arthritis.</p>Formula:C14H13NOMolecular weight:211.09971α-Glucosidase-IN-65
<p>α-Glucosidase-IN-65 (compound 5) is a Schiff base derivative of 3,4-dihydroxyphenylacetic acid. It acts as a potent α-glucosidase inhibitor with an IC50 of 12.84 μM.</p>Formula:C15H14N2O6Molecular weight:318.08519LTA4H-IN-4
<p>LTA4H-IN-4 (compound 3) is an orally active inhibitor of LTA4H. It exhibits an IC50 value of 156 μM against hERG and is applicable for inflammation-related research.</p>CTL26
<p>CTL26 is an effective, orally active α-glucosidase inhibitor, with an IC50 value of 2.81 µM, demonstrating antidiabetic properties.</p>Formula:C25H18N6O3SMolecular weight:482.11611MPO-IN-6
<p>MPO-IN-6 (compound ADC) is an electrophilic agent with excellent antioxidant and anti-inflammatory properties. It acts as an inhibitor of myeloperoxidase (MPO), dipeptidyl peptidase-4 (DPP-4), and α-glucosidase (α-GD), with IC50 values of 10 μM, 31.02 μM, and 46.05 μM, respectively. MPO-IN-6 may serve as a potential cardiovascular protective agent.</p>Formula:C16H12N2O6Molecular weight:328.06954PTP1B-IN-25
<p>PTP1B-IN-25 (Compound 19) is an inhibitor of PTP1B with notable antiviral, antibacterial, and antidiabetic activities. It exhibits IC50 values of 0.37 μM for PTP1B, 8.6 μM for HIV, 3.7 μM for α-Glucosidase, and 29 μM for methicillin-resistant Staphylococcus aureus (MRSA).</p>Formula:C44H66O17Molecular weight:866.43
