Metabolism
Metabolism inhibitors are compounds that interfere with metabolic pathways, altering the production and utilization of energy within cells. These inhibitors are used to study the regulation of metabolism, the role of metabolic pathways in diseases like cancer and diabetes, and to develop new therapeutic strategies. Metabolism inhibitors can target various enzymes and processes involved in glycolysis, fatty acid oxidation, and other metabolic functions. At CymitQuimica, we offer a wide range of high-quality metabolism inhibitors to support your research in biochemistry, metabolic disorders, and drug development.
Subcategories of "Metabolism"
- AhR(41 products)
- Aminopeptidase(67 products)
- CETP(18 products)
- Carbonic Anhydrase(177 products)
- Casein Kinase(130 products)
- DHFR(32 products)
- Decarboxylase(4 products)
- Dehydrogenase(267 products)
- FAAH(63 products)
- FXR(58 products)
- Factor Xa(80 products)
- Fatty Acid Synthase(32 products)
- Ferroptosis(215 products)
- GR(3 products)
- GSNOR(3 products)
- Glucokinase(53 products)
- HIF/HIF Prolyl-Hydroxylase(142 products)
- HMG-CoA Reductase(32 products)
- Hydroxylase(30 products)
- IDO(82 products)
- LDL(8 products)
- Lipase(96 products)
- Lipid(59 products)
- Lipoxygenase(124 products)
- MAO(87 products)
- MPO(2 products)
- NAMPT(36 products)
- P450(6 products)
- PAI-1(25 products)
- PDE(166 products)
- PED(1 products)
- PKM(15 products)
- PPAR(164 products)
- Phospholipase(82 products)
- ROR(42 products)
- Retinoid Receptor(29 products)
- SGK(11 products)
- Thioredoxin(12 products)
- Transferase(30 products)
- Transporter(42 products)
- UGT(4 products)
- Xanthine Oxidase (XO) Inhibitors(9 products)
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Found 8595 products of "Metabolism"
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9AzNue5Ac
CAS:<p>9AzNue5Ac is a Neu5Ac analog that is metabolized in vivo in living cells and in mice.9AzNue5Ac binds to sialoglycans.</p>Formula:C11H18N4O8Purity:≥98%Color and Shape:SolidMolecular weight:334.28DSPE-PEG2000-YIGSR
<p>DSPE-PEG2000-YIGSR is a PEG compound composed of DSPE and the biomimetic peptide YIGSR. YIGSR interacts with the 67 kDa laminin-binding protein (LBP), enhancing the adhesion and proliferation of various cell types, including endothelial cells, fibroblasts, and smooth muscle cells. DSPE-PEG2000-YIGSR is applicable in drug delivery.</p>Color and Shape:Odour SolidLodenafil carbonate
CAS:<p>Lodenafil carbonate is a prodrug, orally used as a PDE5 inhibitor for ED treatment.</p>Formula:C47H62N12O11S2Color and Shape:SolidMolecular weight:1035.21DPP IV/hCA II-IN-1
CAS:<p>DPP IV/hCA II-IN-1: strong DPP IV & CA inhibitor, IC50=0.049μM (DPP IV), Ki=0.0361-3.034μM (CA II-IV).</p>Formula:C17H20N2O5SColor and Shape:SolidMolecular weight:364.42ATX inhibitor 7
CAS:<p>ATX inhibitor 7 is a autotaxin inhibitor and shows good oral exposure.</p>Formula:C21H22F3N7O2Color and Shape:SolidMolecular weight:461.449Adefovir diphosphate 2TEA
<p>Adefovir diphosphate 2TEA,a metabolite of Adefovir, an oral reverse transcriptase inhibitor with antiviral activity against herpes, hepatitis B, and HIV.</p>Formula:C20H43N7O7P2Purity:98.33%Color and Shape:SolidMolecular weight:555.55Sofosbuvir impurity C
CAS:<p>Sofosbuvir impurity C, a less active byproduct, inhibits HCV RNA replication and exhibits strong anti-HCV effects.</p>Formula:C22H29FN3O9PPurity:98%Color and Shape:SolidMolecular weight:529.45Ferulic acid acyl-β-D-glucoside
CAS:<p>Ferulic acid acyl-β-D-glucoside, a metabolite of Ferulic Acid, is a novel inhibitor of fibroblast growth factor receptor 1 (FGFR1).</p>Formula:C16H20O9Color and Shape:SolidMolecular weight:356.327ACAT-IN-2
CAS:<p>ACAT-IN-2, from EP1236468A1 (ex. 187), inhibits ACAT and blocks NF-κB transcription.</p>Formula:C29H44N2O4SColor and Shape:SolidMolecular weight:516.74T3 Acyl glucuronide
CAS:<p>T3 Acyl glucuronide is the acyl glucuronide formation of triiodothyronine (T3). T3 Acyl glucuronide is an endogenous metabolite</p>Formula:C21H20I3NO10Purity:98%Color and Shape:SolidMolecular weight:827.1ONO-8430506
CAS:<p>ONO-8430506 is an orally available, potent autotaxin (ATX)/ENPP2 inhibitor (IC90: 100 nM) that inhibits ATX activity in mouse plasma.</p>Formula:C27H28FN3O3Purity:98.34%Color and Shape:SolidMolecular weight:461.53PDE12-IN-1
CAS:<p>PDE12-IN-1, a potent PDE12 inhibitor with a pIC50 of 9.1, increases 2-5A, has a pEC50 of 7.7, and shows antiviral properties.</p>Formula:C31H27BrFN5O3Color and Shape:SolidMolecular weight:616.491DSPE-PEG2000-APRPG
<p>DSPE-PEG2000-APRPG is a PEG compound composed of DSPE and the APRPG peptide. It is utilized in drug delivery applications.</p>Color and Shape:Odour Solid2,5-Anhydro-D-glucitol-1,6-diphosphate
CAS:<p>2,5-Anhydro-D-glucitol-1,6-diphosphate mildly stimulates yeast Pyruvate Kinase; it's an analogue of a potent activator.</p>Formula:C6H14O11P2Color and Shape:SolidMolecular weight:324.12Methyl 3,4,5-trimethoxy-2-(2-(nicotinamido)benzamido)benzoate
CAS:<p>Preterramide C is a fungal metabolite that has been found inA.</p>Formula:C24H23N3O7Color and Shape:SolidMolecular weight:465.46BDM_92499
<p>BDM_92499 is a nanomolar, selective IRAP inhibitor with an IC50 of 3.4 nM. It also inhibits ERAP1 and ERAP2, with IC50 values of 0.46 μM and 4.2 μM, respectively.</p>Color and Shape:Odour SolidCarbazeran citrate
CAS:<p>aldehyde oxidase (AO) substrate</p>Formula:C24H32N4O11Purity:98%Color and Shape:SolidMolecular weight:552.53ZINC77292789
CAS:<p>ZINC77292789 (Fmoc-Thr[GalNAc(Ac)3-α-D]-OH) is a reagent for the preparation of a synthetic MUC1 Glycopeptide Bearing βGalNAc-Thr as a Tn antigen isomer which</p>Formula:C33H38N2O13Purity:99.24%Color and Shape:SolidMolecular weight:670.66hCAII-IN-8
CAS:<p>Compound CDy9 is a highly selective inhibitor of carbonic anhydrase (CA) with an IC50 value of 0.18 μM for hCA II.</p>Formula:C15H16N2O5SPurity:99.73%Color and Shape:SoildMolecular weight:336.36Galactose 1-phosphate
CAS:<p>Galactose 1-phosphate, an intermediate substance in both galactose metabolism and nucleotide sugar processes, plays a crucial role in the biochemical pathways</p>Formula:C6H13O9PPurity:98%Color and Shape:SolidMolecular weight:260.14PDE10A-IN-5
<p>PDE10A-IN-5 (Compound A30) is an orally active inhibitor of phosphodiesterase 10A (PDE10A) with an IC50 value of 3.5 nM. By inhibiting PDE10A, it activates the cyclic adenosine monophosphate (cAMP)-related signaling pathway, exhibiting activity against pulmonary vascular remodeling. This compound is applicable to research in the field of pulmonary arterial hypertension.</p>Color and Shape:Odour SolidResveratrol-3-O-sulfate sodium
CAS:<p>Resveratrol-3-O-sulfate reduces IL-1α/β, IL-6, TNF-α in LPS-stimulated U-937 cells, inhibits Caco-2 cell growth, induces apoptosis, and binds mitoNEET.</p>Formula:C14H11NaO6SColor and Shape:SolidMolecular weight:330.29DSPE-PEG5000-VIP
<p>DSPE-PEG5000-PP1 is a PEG compound composed of DSPE and the cell-penetrating peptide (TAT) peptide. DSPE-PEG2000-TAT is applicable for drug delivery.</p>Color and Shape:Odour Solidtetranor-PGEM
CAS:<p>Tetranor-PGEM, the primary urinary byproduct of PGE1 and PGE2, marks PGE2 production; humans excrete 7-40 μg daily.</p>Formula:C16H24O7Color and Shape:SolidMolecular weight:328.361Galactosylhydroxylysine
CAS:<p>Galactosylhydroxylysine, a bone collagen breakdown product, is released during bone resorption and excreted in urine.</p>Formula:C12H24N2O8Color and Shape:SolidMolecular weight:324.33Impurity C of Alfacalcidol
CAS:<p>Impurity of Alfacalcidol is an impurity of Alfacalcidol. Alfacalcidol is a non-selective VDR activator medication.</p>Formula:C35H49N3O4Purity:98%Color and Shape:SolidMolecular weight:575.78Epicoccamide
CAS:<p>Epicoccamide is a marine fungal metabolite originally isolated from E. purpurascens.</p>Formula:C29H51NO9Color and Shape:SolidMolecular weight:557.72Lurasidone Metabolite 14283 hydrochloride
CAS:<p>Lurasidone Metabolite 14283 hydrochloride is a major active metabolite of Lurasidone.</p>Formula:C28H37ClN4O3SPurity:98%Color and Shape:SolidMolecular weight:545.143-HIB
CAS:<p>3-HIB is a paracrine regulator of transendothelial fatty acid transport.</p>Formula:C4H7NaO3Color and Shape:SolidMolecular weight:126.09SDUY817
<p>SDUY817 is a dual APN/NEP inhibitor with IC50 values of 0.29 μM for APN and 7.4 μM for NEP. It exhibits analgesic effects in a concentration- and time-dependent manner, making it a potential candidate for research in the field of neuropathic pain disorders.</p>Formula:C18H16IN3O3Color and Shape:SolidMolecular weight:449.24Hydroxy bosentan
CAS:<p>Hydroxy bosentan (Ro 48-5033), a Bosentan metabolite, is liver-processed with 10-20% of its activity.</p>Formula:C27H29N5O7SPurity:98%Color and Shape:SolidMolecular weight:567.61[(3R)-3-Hydroxydodecanoyl]-L-carnitine
CAS:<p>[(3R)-3-Hydroxydodecanoyl]-L-carnitine is an endogenous metabolite[1].</p>Formula:C19H37NO5Color and Shape:SolidMolecular weight:359.50Tuftsin diacetate
CAS:<p>Tuftsin diacetate, Thr-Lys-Pro-Arg, activates macrophages/microglia; it's in immunoglobulin G's Fc and boosts immunity.</p>Formula:C25H48N8O10Purity:98%Color and Shape:SolidMolecular weight:620.7Monoglyceride lipase
CAS:<p>Monoglyceridelipase is a crucial enzyme involved in lipid metabolism, catalyzing the hydrolysis of monoglycerides (especially 2-AG, or 2-arachidonoylglycerol) into glycerol and free fatty acids. By regulating the levels of 2-AG, this enzyme impacts neural signaling, pain perception, inflammatory responses, and metabolic processes.</p>Color and Shape:Solid1-Methylhistamine
CAS:<p>2-(1-Methyl-1H-imidazol-4-yl)ethan-1-amine is a histamine metabolite.</p>Formula:C6H11N3Purity:98%Color and Shape:SolidMolecular weight:125.1716α-Glucosidase-IN-72
<p>α-Glucosidase-IN-72 (compound 5i), a 2,4-dichloro-N-phenylacetamide derivative, functions as an α-glucosidase inhibitor with an inhibitory concentration (IC 50) of 6 μM. Notably, it does not adhere to Lipinski's "rule of five" and is not a cancer inducer.</p>Formula:C37H26Cl2N4O9Color and Shape:SolidMolecular weight:741.53PP5-IN-2
<p>PP5-IN-2, a selective and orally active inhibitor of protein phosphatase 5 (PP5), exhibits an IC 50 of 0.9 μM. This compound activates p53 and leads to the downregulation of cyclin D1 and MGMT, thereby inducing cell cycle arrest and reversing Temozolomide (TMZ) resistance in the U87 MG cell line. Additionally, PP5-IN-2 has demonstrated effective inhibition of tumor growth in the xenograft mouse model.</p>Formula:C16H15NO4Color and Shape:SolidMolecular weight:285.29Ophiobolin A
CAS:<p>Ophiobolin A: Fungal metabolite, phytotoxin, inhibits calmodulin-activated phosphodiesterase (IC50: 9μM), with antimicrobial and anticancer properties.</p>Formula:C25H36O4Purity:98%Color and Shape:SolidMolecular weight:400.559Penicillinase
CAS:<p>Penicillinase is a β-lactamase and secretory enzyme capable of degrading and inactivating penicillin and similar compounds.</p>Color and Shape:SolidNinerafaxstat trihydrochloride
CAS:<p>Ninerafaxstat trihydrochloride shifts cellular metabolism to glucose oxidation from fatty acid oxidation.</p>Formula:C22H32Cl3N3O5Purity:99.71%Color and Shape:SoildMolecular weight:524.87C-Type Natriuretic Peptide (1-53), Porcine, Rat,mouse
CAS:<p>C-Type Natriuretic Peptide (1-53), from porcine, rat, and mouse sources, serves as an activator of particulate guanylate cyclase B (pGC-B), prominently found in endothelial cells, kidneys, and the heart. This peptide efficiently mediates a potent anti-fibrotic effect in human cardiac and renal fibroblasts through the production of the second messenger cGMP.</p>Color and Shape:Solidα-Glucosidase-IN-84
<p>α-Glucosidase-IN-84 (Compound 7j) is a competitive inhibitor of α-glucosidase, exhibiting an IC50 of 50 μM and a Ki of 32 μM. It shows potential for application in metabolic disease research, particularly in studies related to type 2 diabetes.</p>Formula:C25H29N7O3SColor and Shape:SolidMolecular weight:507.608DSPE-PEG1000-pPB
<p>DSPE-PEG1000-pPB is a PEG compound consisting of DSPE and a cyclic oligopeptide (pPB). The pPB component exhibits a strong binding affinity to PDGFRβ, which is overexpressed in activated hepatic stellate cells (HSC). DSPE-PEG1000-pPB is applicable for drug delivery.</p>Color and Shape:Odour SolidCoprosterol
CAS:<p>Coprosterol is a stanol formed from the biohydrogenation of cholesterol as a biomarker for the presence of human faecal matter in the environment.</p>Formula:C27H48OColor and Shape:SolidMolecular weight:388.673-Nitro-L-tyrosine ethyl ester hydrochloride
<p>3-Nitro-L-tyrosine ethyl ester hydrochloride is a useful organic compound for research related to life sciences and the catalog number is T124433.</p>Formula:C11H15ClN2O5Color and Shape:SolidMolecular weight:290.7α-Glucosidase-IN-73
<p>α-Glucosidase-IN-73 (compound 16b), an α-Glucosidase inhibitor, exhibits an IC 50 value of 0.158 μM and possesses the ability to activate PPAR γ. This compound is applicable in studies focusing on anti-diabetic and anti-inflammatory treatments.</p>Formula:C24H21N3O2SColor and Shape:SolidMolecular weight:415.5118:0,22:6 PS sodium
CAS:<p>Sodium 18:0,22:6 phosphatidylserine (PS) is a lipid found within synaptic vesicles alongside cholesterol, utilized in metabolic research [1].</p>Formula:C46H77NNaO10PColor and Shape:SolidMolecular weight:858.07Doxorubicinone
CAS:<p>Adriamycin Aglycone, also known as Doxorubicinone, is an oncolytic agent. It is a metabolite of Doxorubicin which binds to the DNA minor-groove.</p>Formula:C21H18O9Color and Shape:SolidMolecular weight:414.36Pestalotin
CAS:<p>Pestalotin, a fungal derivative, promotes rice seedling growth and sugar release, has antifungal properties, and is cytotoxic to certain cells.</p>Formula:C11H18O4Color and Shape:SolidMolecular weight:214.26SDUY816
<p>SDUY816 is an orally active dual APN/NEP inhibitor, with IC50 values of 0.68 μM for APN and 6.9 μM for NEP. It exhibits analgesic properties and demonstrates good safety and pharmacokinetic profiles, having an oral bioavailability of 27% and a half-life of 4.02 hours in rats (oral, 10 mg/kg). SDUY816 is applicable for research in the field of neuropathic pain disorders.</p>Formula:C18H16IN3O3Color and Shape:SolidMolecular weight:449.24
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