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Metabolism

Metabolism

Metabolism inhibitors are compounds that interfere with metabolic pathways, altering the production and utilization of energy within cells. These inhibitors are used to study the regulation of metabolism, the role of metabolic pathways in diseases like cancer and diabetes, and to develop new therapeutic strategies. Metabolism inhibitors can target various enzymes and processes involved in glycolysis, fatty acid oxidation, and other metabolic functions. At CymitQuimica, we offer a wide range of high-quality metabolism inhibitors to support your research in biochemistry, metabolic disorders, and drug development.

Subcategories of "Metabolism"

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Found 8597 products of "Metabolism"

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  • ND-011992

    CAS:
    <p>ND-011992: Quinazoline inhibitor of E. coli respiratory enzymes; IC50s: 0.12-2.47 μM; potential tuberculosis research.</p>
    Formula:C21H14F3N3O
    Purity:99.7%
    Color and Shape:Soild
    Molecular weight:381.35
  • UK-383367

    CAS:
    <p>UK-383367 is a procollagen C-proteinase inhibitor with IC50 of 44 nM, has excellent selectivity over MMPs.</p>
    Formula:C15H24N4O4
    Purity:>99.99%
    Color and Shape:Solid
    Molecular weight:324.38
  • WVSAV


    <p>WVSAV is a ligand for the PDZ2 domain (tyrosine phosphatase) with a dissociation constant (Kd) of 111 μM. It is utilized in studies of protein-ligand interactions.</p>
    Formula:C27H40N6O7
    Color and Shape:Solid
    Molecular weight:560.64
  • Xanthine oxidase-IN-9

    CAS:
    <p>Xanthine Oxidase-IN-9 (also known as Icarisids E or Compound 2) effectively inhibits xanthine oxidase (XOD) with an IC50 value of 31.81 μM [1].</p>
    Formula:C38H50O20
    Color and Shape:Solid
    Molecular weight:826.79
  • D-(+)-Trehalose-13C12

    CAS:
    <p>D-(+)-Trehalose-13C12 is an isotopic label of D-(+)-Trehalose, enriched with 13C. This compound is pervasively found and often employed as a food ingredient and a shape-forming agent for active molecules.</p>
    Formula:C12H22O11
    Color and Shape:Solid
    Molecular weight:354.21
  • 13,14-dehydro-15-cyclohexyl Carbaprostacyclin

    CAS:
    <p>13,14-dehydro-15-cyclohexyl Carbaprostacyclin, a stable PGI2 analog, impedes ADP-induced platelet aggregation; ED50 ~40 nM in PRP, 77 nM in washed platelets.</p>
    Formula:C21H30O4
    Color and Shape:Solid
    Molecular weight:346.467
  • 13-cis-Retinyl acetate

    CAS:
    <p>13-cis-Retinyl acetate: active 13-cis isomer of Retinyl acetate, metabolite of vitamin A.</p>
    Formula:C22H32O2
    Color and Shape:Solid
    Molecular weight:328.49
  • Ionizable Lipid 4

    CAS:
    <p>Ionizable Lipid 4 is an ionizable cationic lipid that forms as a product of the rearrangement of cationic lipid CA-lipid 5 under hydrogen peroxide induction.</p>
    Formula:C48H85NO7
    Color and Shape:Solid
    Molecular weight:788.19
  • Senecionine acetate

    CAS:
    <p>Senecionine acetate, a pyrrolizidine alkaloid, blocks Ca2+ storage in cells by inactivating sulfhydryl groups.</p>
    Formula:C20H27NO6
    Color and Shape:Solid
    Molecular weight:377.43
  • hCA XII-IN-6


    <p>Compound 4d, known as hCA XII-IN-6, is a potent inhibitor of human carbonic anhydrase XII (hCA XII) with a Ki value of 84.2 nM and exhibits anti-proliferative</p>
    Formula:C11H9N5O3S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:323.35
  • Kazusamycin A

    CAS:
    <p>Kazusamycin A is a new antitumor antibiotic.</p>
    Formula:C33H48O7
    Color and Shape:Solid
    Molecular weight:556.74
  • H-Tyr-Ala-OH

    CAS:
    <p>Tyrosylalanine (H-Tyr-Ala-OH), a dipeptide comprising L-tyrosine and L-alanine, is referenced in studies [1] [2].</p>
    Formula:C12H16N2O4
    Purity:99.74%
    Color and Shape:Solid
    Molecular weight:252.27
  • 1-Myristoyl-2-stearoyl-sn-glycero-3-phosphocholine

    CAS:
    <p>Endogenous metabolite: 1-myristoyl-2-stearoyl-sn-glycero-3-phosphocholine, a phosphatidylcholine example.</p>
    Formula:C40H80NO8P
    Purity:99.23%
    Color and Shape:Solid
    Molecular weight:734.04
  • Prenisteine

    CAS:
    <p>Prenisteine is a bioactive chemical.</p>
    Formula:C8H15NO2S
    Color and Shape:Solid
    Molecular weight:189.275
  • Boc-L-aspartic acid 4-benzyl ester

    CAS:
    <p>Boc-L-aspartic acid 4-benzyl ester (Boc-Asp(OBzl)-OH) is an aspartic acid derivative.</p>
    Formula:C16H21NO6
    Purity:99.57%
    Color and Shape:Solid
    Molecular weight:323.34
  • Conagenin

    CAS:
    <p>Conagenin is a small molecular immunomodulator isolated by Streptomyces roseosporus.</p>
    Formula:C10H19NO6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:249.26
  • (S,S)-GSK321

    CAS:
    <p>(S,S)-GSK321 is a (S,S)-enantiomer of GSK321 [1] .</p>
    Formula:C28H28FN5O3
    Color and Shape:Solid
    Molecular weight:501.55
  • Sucrose phosphorylase

    CAS:
    <p>Sucrose phosphorylase, a bacterial enzyme, transforms sucrose and phosphate into α-D-glucose-1-phosphate and D-fructose.</p>
    Color and Shape:Solid
  • α-Glucosidase-IN-26


    <p>α-Glucosidase-IN-26 (Compound 7i), with an IC50 value of 4.63 µM, functions as an α-glucosidase inhibitor and is utilized in research related to type 2 diabetes</p>
    Formula:C23H22ClN3O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:455.89
  • HIF-1 inhibitor-5


    <p>HIF-1 inhibitor-5 (Compound 16e) is a potent inhibitor of HIF-1, exhibiting an IC50 value of 2.38 μM and demonstrating significant anti-angiogenic potential [1</p>
    Formula:C28H35NO5
    Color and Shape:Solid
    Molecular weight:465.58
  • 2,3,4,5-Tetrachlorophenol

    CAS:
    <p>2,3,4,5-Tetrachlorophenol, a γ-lindane byproduct, is toxic to minnows, trout (LC50: 0.496, 0.304 mg/L).</p>
    Formula:C6H2Cl4O
    Color and Shape:Solid
    Molecular weight:231.88
  • Ninerafaxstat trihydrochloride

    CAS:
    <p>Ninerafaxstat trihydrochloride shifts cellular metabolism to glucose oxidation from fatty acid oxidation.</p>
    Formula:C22H32Cl3N3O5
    Purity:99.71%
    Color and Shape:Soild
    Molecular weight:524.87
  • (S)-3,4-Dihydroxybutyric acid lithium hydrate


    <p>(S)-3,4-Dihydroxybutyric acid (Li hydrate) is a urinary metabolite; higher in SSADH deficiency cases.</p>
    Formula:C4H9LiO5
    Color and Shape:Solid
    Molecular weight:144.05
  • ACAT-IN-4 hydrochloride

    CAS:
    <p>ACAT-IN-4 hydrochloride is a potent ACAT inhibitor and blocks NF-κB transcription.</p>
    Formula:C32H51ClN2O5S
    Color and Shape:Solid
    Molecular weight:611.28
  • Mesembrenone

    CAS:
    <p>Mesembrenone is a selective the serotonin transporter (SERT) inhibitor. Mesembrenone is the main alkaloid of Sceletium tortuosum.</p>
    Formula:C17H21NO3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:287.35
  • α-Amylase/α-Glucosidase-IN-16


    <p>α-Amylase/α-Glucosidase-IN-16 (compound 15) is a potent dual inhibitor of α-amylase and α-glucosidase, with IC50 values of 0.8 μM and 1.2 μM, respectively. It is applicable for research in diabetes (DM).</p>
    Formula:C16H9Cl2F3N4S
    Molecular weight:415.98771
  • (Rac)-sn-Glycerol 3-phosphate sodium

    CAS:
    <p>(Rac)-sn-Glycerol 3-phosphate sodium, an a-site substrate analogue, inhibits indole reactions with E(A-A).</p>
    Formula:C3H7Na2O6P
    Color and Shape:Solid
    Molecular weight:216.04
  • D-Pro-Phe-Arg-Chloromethylketone

    CAS:
    <p>D-Pro-Phe-Arg-Chloromethylketone, an inhibitor of coagulation factor XII and plasma kallikrein, is significant in the regulation of thrombosis and inflammation</p>
    Formula:C21H31ClN6O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:450.96
  • α-Glucosidase-IN-67


    <p>α-Glucosidase-IN-67 (compound 5k) is a potent inhibitor of α-glucosidase, exhibiting IC50 values of 0.31 µM for α-glucosidase and 4.51 µM for α-amylase. This compound shows potential for research in type 2 diabetes.</p>
    Formula:C24H22BrN3O3S
    Molecular weight:511.05653
  • 9-PAHPA

    CAS:
    <p>9-PAHPA, a fatty acid ester of hydroxy fatty acid (FAHFA), belongs to a recently identified family of endogenous lipids known for their antidiabetic and anti-</p>
    Formula:C32H62O4
    Color and Shape:Solid
    Molecular weight:510.83
  • Cytoglobosin C

    CAS:
    <p>Cytoglobosin C, a derivative of cytochalasan, demonstrates significant cytotoxic effects on SGC-7901 and A549 cell lines, with an inhibitory concentration (IC50</p>
    Formula:C32H38N2O5
    Color and Shape:Solid
    Molecular weight:530.65
  • Milpocitide

    CAS:
    <p>Milpocitide, a (293-333)-peptide fragment of the human low-density lipoprotein receptor (LDLR), specifically corresponds to the EGF-like domain 1 [1].</p>
    Formula:C255H413N63O86S6
    Color and Shape:Solid
    Molecular weight:5929.75
  • N-Methyl pemetrexed

    CAS:
    <p>N-Methyl pemetrexed, an impurity found in Pemetrexed, serves as an antifolate cytotoxic agent utilized in cancer research [1].</p>
    Formula:C21H23N5O6
    Color and Shape:Solid
    Molecular weight:441.44
  • Transketolase-IN-6


    <p>Transketolase-IN-6 (Compound 6bj) serves as a lead compound for herbicides. It achieves approximately 80% root inhibition in redroot pigweed (Amaranthus retroflexus) and green foxtail (Setaria viridis). Moreover, Transketolase-IN-6 is an effective inhibitor of transketolase (TK).</p>
    Formula:C23H27ClN6O
    Molecular weight:438.19349
  • Formate dehydrogenase

    CAS:
    <p>Formate dehydrogenase, found in all life forms, converts formate to CO2 and is categorized by metal content for research.</p>
    Color and Shape:Solid
  • hCAIX/XII-IN-11


    <p>hCAIX/XII-IN-11 (Compound 6c) is an inhibitor of hCA IX and hCA XII, exhibiting Ki values of 0.7 μM for both isoforms. This compound is applicable in cancer research.</p>
    Formula:C13H10FN3O4
    Molecular weight:291.06553
  • IPI-9119

    CAS:
    <p>IPI-9119 is an orally active, selective and irreversible FASN inhibitor (IC50 = 0.3 nM).</p>
    Formula:C24H19F2N5O5
    Purity:99.81%
    Color and Shape:Solid
    Molecular weight:495.43
  • HSP90-IN-30


    <p>HSP90-IN-30 (compound 3e) inhibits the activity of the HSP90 molecular chaperone. Under hypoxic conditions, HSP90-IN-30 suppresses HIF-1 transcriptional activity with an IC50 value of 2.16 μM.</p>
    Formula:C20H39B12N4O2
    Molecular weight:499.41897
  • FXIIa-IN-4


    <p>FXIIa-IN-4 (compound 22) is a potent and selective human FXIIa inhibitor, exhibiting IC50 values of 0.032 μM for FXIIa, 0.30 μM for thrombin, and &gt;50 μM for FXIa. It is utilized in anticoagulant research.</p>
    Formula:C11H9FN4O3
    Molecular weight:264.06587
  • PTP1B-IN-13

    CAS:
    <p>PTP1B-IN-13 inhibits PTP1B at an allosteric site with 1.59 μM IC50.</p>
    Formula:C24H25N3O3S2
    Color and Shape:Solid
    Molecular weight:467.6
  • 2-NP-AMOZ

    CAS:
    <p>2-NP-AMOZ, a 2-nitrophenyl AMOZ, detects protein-bound AMOZ, a Furaltadone metabolite.</p>
    Formula:C15H18N4O5
    Color and Shape:Solid
    Molecular weight:334.33
  • Clostripain

    CAS:
    <p>Clostripain is a protease from Clostridium with esterase, amidase activities, targeting arginine.</p>
    Color and Shape:Solid
  • NAMPT activator-7


    <p>NAMPTactivator-7 (Compound 232) is an activator of nicotinamide phosphoribosyltransferase (NAMPT) with an EC50 of less than 0.5 μM. It effectively stimulates NAMPT in U2OS cells, demonstrating a cellular EC50 of less than 0.5 μM.</p>
    Formula:C21H17ClN4O3
    Molecular weight:408.09892
  • Ganglioside sialidase (AuSialidase S)

    CAS:
    <p>AuSialidase S is an endogenous metabolite involved in neuronal differentiation and neurite outgrowth.</p>
    Color and Shape:Solid
  • IGUANA-1 free base

    CAS:
    <p>IGUANA-1: selective ALDH1 B1 inhibitor, IC50=30 nM, hinders SW480 cell growth with IC50=2.46/0.39 μM in adherent/spheroid forms, for cancer research.</p>
    Formula:C26H24ClN3O2
    Color and Shape:Solid
    Molecular weight:445.94
  • Morin 3-O-β-D-glucopyranoside

    CAS:
    <p>Morin 3-O-β-D-glucopyranoside, a natural flavonoid, exhibits antifungal, anticancer, and antioxidant properties.</p>
    Formula:C21H20O12
    Color and Shape:Solid
    Molecular weight:464.38
  • Endoglycoceramidase II (EGCase II)

    CAS:
    <p>EGCase II is an enzyme breaking down the glycan-ceramide bond in glycosphingolipids.</p>
    Color and Shape:Solid
  • SDUY817


    <p>SDUY817 is a dual APN/NEP inhibitor with IC50 values of 0.29 μM for APN and 7.4 μM for NEP. It exhibits analgesic effects in a concentration- and time-dependent manner, making it a potential candidate for research in the field of neuropathic pain disorders.</p>
    Formula:C18H16IN3O3
    Color and Shape:Solid
    Molecular weight:449.24
  • ST6 Sialyltransferase 5


    <p>ST6Sialyltransferase5 (EC:2.4.3.3, ST6GALNAC5, SIAT7E, ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5) transfers sialic acid to N-acetylgalactosamine (GalNAc) residues. It may serve as a biomarker in cervical screening samples.</p>
  • Leukotriene C4 methyl ester

    CAS:
    <p>LTC4, made by neutrophils and others via LTC4 synthase, causes smooth muscle contractions and is involved in asthma/allergic responses.</p>
    Formula:C31H49N3O9S
    Color and Shape:Solid
    Molecular weight:639.81