Metabolism
Metabolism inhibitors are compounds that interfere with metabolic pathways, altering the production and utilization of energy within cells. These inhibitors are used to study the regulation of metabolism, the role of metabolic pathways in diseases like cancer and diabetes, and to develop new therapeutic strategies. Metabolism inhibitors can target various enzymes and processes involved in glycolysis, fatty acid oxidation, and other metabolic functions. At CymitQuimica, we offer a wide range of high-quality metabolism inhibitors to support your research in biochemistry, metabolic disorders, and drug development.
Subcategories of "Metabolism"
- AhR(42 products)
- Aminopeptidase(76 products)
- CETP(20 products)
- Carbonic Anhydrase(196 products)
- Casein Kinase(139 products)
- DHFR(30 products)
- Decarboxylase(4 products)
- Dehydrogenase(302 products)
- FAAH(64 products)
- FXR(62 products)
- Factor Xa(87 products)
- Fatty Acid Synthase(37 products)
- Ferroptosis(227 products)
- GR(3 products)
- GSNOR(3 products)
- Glucokinase(56 products)
- HIF/HIF Prolyl-Hydroxylase(146 products)
- HMG-CoA Reductase(34 products)
- Hydroxylase(36 products)
- IDO(84 products)
- LDL(7 products)
- Lipase(107 products)
- Lipid(62 products)
- Lipoxygenase(133 products)
- MAO(85 products)
- MPO(2 products)
- NAMPT(40 products)
- P450(6 products)
- PAI-1(26 products)
- PDE(170 products)
- PED(1 products)
- PKM(17 products)
- PPAR(170 products)
- Phospholipase(85 products)
- ROR(47 products)
- Retinoid Receptor(18 products)
- SGK(10 products)
- Thioredoxin(12 products)
- Transferase(30 products)
- Transporter(43 products)
- UGT(4 products)
- Xanthine Oxidase (XO) Inhibitors(9 products)
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Found 9194 products of "Metabolism"
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L-Lactate dehydrogenase
CAS:L-Lactate dehydrogenase is an enantiospecific redox enzyme reducing pyruvate to L-lactate using NADH.Color and Shape:SolidFebuxostat n-butyl isomer
CAS:Febuxostat n-butyl isomer is an impurity of Febuxostat. Febuxostat is selective xanthine oxidase inhibitor with a K i of 0.6 nM [1] .Formula:C16H16N2O3SColor and Shape:SolidMolecular weight:316.38ML266
CAS:ML266: GCase chaperone, non-inhibiting, IC50=2.5 µM, aids mutant protein transport, may help in Gaucher disease study.Formula:C24H22BrN3O4Purity:99.58%Color and Shape:SolidMolecular weight:496.35Ref: TM-T8990
1mg50.00€2mg71.00€5mg105.00€10mg166.00€25mg325.00€50mg449.00€100mg652.00€500mg1,369.00€1mL*10mM (DMSO)114.00€MTHFD2-IN-4 sodium
MTHFD2-IN-4 sodium, a potent inhibitor of MTHFD2 and a tricyclic coumarin derivative, is applicable in cancer research [1].Formula:C26H21F6N2NaO5Color and Shape:SolidMolecular weight:578.44Boc-Ile-Glu-Gly-Arg-AMC
CAS:Boc-IEGR-AMC: fluorogenic substrate for factor Xa and Halocynthia roretzi acrosin.Formula:C34H50N8O10Purity:98%Color and Shape:White PowderMolecular weight:730.81MSI-1436 lactate
CAS:MSI-1436 lactate is a selective, non-competitive the enzyme protein-tyrosine phosphatase 1B (PTB1B)inhibitor(IC50 of appr 1 μM)Formula:C37H72N4O5SC3H6O3Purity:98%Color and Shape:SolidMolecular weight:1000.17Tauro-α-muricholic Acid (sodium salt)
CAS:Tauro-α-muricholic acid (TαMCA) is an antagonist of the farnesoid X receptor (FXR; IC50 = 28 μM) and a taurine-conjugated form of the murine-specific primaryFormula:C26H44NNaO7SColor and Shape:SolidMolecular weight:537.69ATP ditromethamine
CAS:ATP ditromethamine is key for energy storage, metabolism, and acts as a coenzyme and signaling molecule in immunity and inflammation.Formula:C18H38N7O19P3Color and Shape:SolidMolecular weight:749.45α-Hydroxytamoxifen
CAS:α-Hydroxytamoxifen is a metabolite of tamoxifen. It reacts with DNA and causes the formation of DNA adducts.Formula:C26H29NO2Purity:98%Color and Shape:SolidMolecular weight:387.51MTHFD2-IN-3
MTHFD2-IN-3 (compound 10), a potent inhibitor of methylenetetrahydrofolate dehydrogenase (MTHFD2), demonstrates significant efficacy in obstructing the activityFormula:C22H19NO7SColor and Shape:SolidMolecular weight:441.45TC HSD 21
CAS:TC HSD 21 is a potent and highly selective inhibitor of 17β-hydroxysteroid dehydrogenase type 3 (IC50 = 14 nM).Formula:C17H12BrNO3S2Purity:99.32%Color and Shape:SolidMolecular weight:422.32Ref: TM-T13100
1mg39.00€5mg86.00€10mg130.00€25mg225.00€50mg326.00€100mg439.00€200mg592.00€1mL*10mM (DMSO)95.00€Methylcardol triene
CAS:Methylcardol triene, a phenolic compound present in cashew nut shell liquid, demonstrates α-glucosidase inhibition (IC50= 39.6 µM) and exhibits schistosomicidal properties by eliminating 100% of adult S. mansoni worms within 24 hours at 100 and 200 µM concentrations. Moreover, it serves as a precursor for synthesizing mono- and bis-benzoxazines.Formula:C22H32O2Color and Shape:SolidMolecular weight:328.496Carboxyaminoimidazole ribotide
CAS:CAIR, an E. coli metabolite, helps identify its PurE active site and aids in fungal purine synthesis.Formula:C9H14N3O9PColor and Shape:SolidMolecular weight:339.2Lantanose A
CAS:Lantanose A is a bioactive chemical from Lantana cumara roots.Formula:C30H52O26Purity:98%Color and Shape:SolidMolecular weight:828.72CyPep-1
CAS:CyPep-1 is a novel cationic lytic peptide with antitumor activity. It exerts potent cytotoxicity by interacting with the negatively charged membranes of cancer cells. CyPep-1 demonstrates strong cell lytic activity against cancer cells both in vitro and in vivo, making it useful for researching solid tumors.Formula:C152H265N57O35Color and Shape:SolidMolecular weight:3451.09hCA/VEGFR-2-IN-4
hCA/VEGFR-2-IN-4 (compound 15b), an indolinylbenzenesulfonamide, serves as a potential dual inhibitor targeting cancer-related human carbonic anhydrases hCA IX/Formula:C22H23FN6O5SPurity:98%Color and Shape:SolidMolecular weight:502.52DSPE-PEG5000-VIP
DSPE-PEG5000-PP1 is a PEG compound composed of DSPE and the cell-penetrating peptide (TAT) peptide. DSPE-PEG2000-TAT is applicable for drug delivery.Color and Shape:Odour Solid(S,R,S)-AHPC-C2-amide-benzofuranylmethyl-pyridine
CAS:(S,R,S)-AHPC-C2-amide targets Smad3 degradation and boosts HIF-α; it has anti-fibrotic and renal protective roles.Formula:C41H46N6O6SColor and Shape:SolidMolecular weight:750.91N-Nitrosoglyphosate sodium
CAS:N-Nitrosoglyphosate sodium, a nitrosamine degradation product and synthetic impurity of glyphosate herbicide [1], is a chemical compound resulting from theFormula:C3H6N2NaO6PColor and Shape:SolidMolecular weight:220.05Impurity F of Calcipotriol
CAS:Impurity F of Calcipotriol is a impurity of Calcipotriol. Calcipotriol (MC 903; Calcipotriene) is a ligand of VDR-like receptors.Formula:C39H68O3Si2Purity:98%Color and Shape:SolidMolecular weight:641.13α-Glucosidase-IN-65
α-Glucosidase-IN-65 (compound 5) is a Schiff base derivative of 3,4-dihydroxyphenylacetic acid. It acts as a potent α-glucosidase inhibitor with an IC50 of 12.84 μM.Formula:C15H14N2O6Molecular weight:318.08519DSPE-PEG1000-WYRGRL
DSPE-PEG1000-WYRGRL consists of DSPE and a cartilage-targeting peptide (WYRGRL) as a PEG compound. WYRGRL is a type II collagen-targeting peptide that can bind to type II collagen α1. DSPE-PEG1000-WYRGRL is suitable for drug delivery applications.Color and Shape:Odour SolidROC-0929
CAS:ROC-0929 (13a) is a selective sPLA2 inhibitor with IC50 of 80 nM, targeting hGX and blocking ERK1/2, p-38 phosphorylation for inflammation research.Formula:C30H31N3O6SColor and Shape:SolidMolecular weight:561.65L-Hisidine monohydrocholoride
CAS:L-Hisidine is an essential amino acid for infants and acts as an inhibitor of mitochondrial glutamine transport.Formula:C6H10ClN3O2Color and Shape:SolidMolecular weight:191.62Biotin-Vitamin B12
Biotin-Vitamin B12, a biotinylated form, is crucial for brain, nervous system function, and blood formation.Formula:C73H102CoN16O16PSColor and Shape:SolidMolecular weight:1581.66DSPE-PEG1000-CGKRK
DSPE-PEG1000-CGKRK is a PEG compound composed of DSPE and the cell-penetrating peptide (CGKRK). It is utilized for drug delivery.Color and Shape:Odour SolidN4-Acetylcytidine triphosphate
CAS:N4-Acetylcytidine triphosphate is efficiently used as a substrate in T7 Polymerase-catalyzed in vitro transcription .Formula:C11H18N3O15P3Purity:98%Color and Shape:SolidMolecular weight:525.19Echinocandin B
CAS:Echinocandin B: a cyclic hexapeptide from A. nidulans, inhibits fungal cell wall synthesis by blocking beta-1,3-glucan.Formula:C52H81N7O16Color and Shape:SolidMolecular weight:1060.24α-glucosidase/PTP1B-IN-1
α-glucosidase/PTP1B-IN-1 (compound 8a) is an effective inhibitor of both α-glucosidase and PTP1B, with IC50 values of 66.3 μM and 47.0 μM, respectively. It also exhibits strong inhibitory activity against α-amylase, having an IC50 of 30.62 μM. This compound is capable of binding to the active sites of α-glucosidase and PTP1B. α-glucosidase/PTP1B-IN-1 holds potential for reducing postprandial blood glucose levels and may be useful in managing type 2 diabetes.Formula:C23H20Cl2O5Color and Shape:SolidMolecular weight:447.31GS-493
CAS:GS-493: Specific SHP2 inhibitor, very potent (IC50=71 nM), 29x affinity vs. SHP1, 45x vs. PTP1B; hinders cancer cell growth/movement.Formula:C21H14N6O8SColor and Shape:SolidMolecular weight:510.44HIF-PHD-IN-4
HIF-PHD-IN-4 (Compound 13) is an orally active PHD2 inhibitor with an IC50 of 100 nM. At a dose of 2 mg/kg, it effectively enhances G-CSF-induced mobilization of hematopoietic stem cells in mice. HIF-PHD-IN-4 is suitable for research in the oncology field.Color and Shape:Odour SolidhCYP3A4-IN-1
hCYP3A4-IN-1 (compound C6) is a potent, orally active inhibitor of hCYP3A4, exhibiting IC50 values of 43.93 nM in human liver microsomes (HLMs) and 153.00 nM inColor and Shape:Odour SolidSR-4995
CAS:SR-4995 (CID 16016685) is an ABHD5 ligand, directly binding to ABHD5 and stimulating lipolysis by releasing it from PLIN.Formula:C19H21N3O2SColor and Shape:SoildMolecular weight:355.45Galactose 1-phosphate
CAS:Galactose 1-phosphate, an intermediate substance in both galactose metabolism and nucleotide sugar processes, plays a crucial role in the biochemical pathwaysFormula:C6H13O9PPurity:98%Color and Shape:SolidMolecular weight:260.14Picornain 3C
CAS:Picornain 3C, a protease in picornaviruses, cleaves Gln-Gly bonds in poliovirus polyproteins and similar sites in others.Color and Shape:Solid(±)13(14)-DiHDPA
CAS:(±)13(14)-DiHDPA is a metabolite of docosahexaenoic acid that is produced via oxidation by cytochrome P450 epoxygenases.Formula:C22H34O4Color and Shape:SolidMolecular weight:362.51H-Ile-Pro-Pro-OH
CAS:H-Ile-Pro-Pro-OH, a milk-derived peptide, inhibits angiotensin-converting enzyme (ACE)[1] with an IC50 of 5 μM.Formula:C16H27N3O4Purity:98%Color and Shape:SolidMolecular weight:325.4Lysophosphatidylethanolamines (egg)
CAS:Lysophosphatidylethanolamines (egg) are the partial hydrolysis products of phosphatidylethanolamine.
Color and Shape:SolidDSPE-PEG2000-NYZL1
DSPE-PEG2000-NYZL1 is a PEG compound composed of DSPE and NYZL1. NYZL1 has the ability to specifically bind to bladder cancer tissues and cells. DSPE-PEG2000-NYZL1 is suitable for drug delivery applications.Color and Shape:Odour SolidCAIX/CAXII-IN-4
CAIX/CAXII-IN-4 (Compound 7h) is an inhibitor of carbonic anhydrase (CA) that binds to CAIX, CA XII, and CAII with Ki values of 1.324 μM, 0.435 μM, and 3.035 μM, respectively. This compound exhibits broad-spectrum anti-tumor activity and inhibits the proliferation of central nervous system tumor cells U251, with a GI50 of 0.361 μM.Formula:C23H21N5O3SColor and Shape:SolidMolecular weight:447.519(S)-HODE cholesteryl ester
CAS:9(S)-HODE cholesteryl ester, from atherosclerotic lesions, has an uncertain origin and serves as a standard for chiral ester analysis.
Formula:C45H76O3Color and Shape:SolidMolecular weight:665.1Diglycyl-histidine
CAS:Diglycyl-histidine is a tripeptide complexed with cupric ion designed to mimic specific Cu(II) transport site of ascorbate on albumin molecule.Formula:C10H15N5O4Color and Shape:SolidMolecular weight:269.26Rubratoxin A
CAS:Rubratoxin A is a classical mycotoxin used as a PP2A-specific inhibitor.Formula:C26H32O11Purity:98%Color and Shape:SolidMolecular weight:520.53118:0,18:1 PS sodium
CAS:18:0,18:1 PS sodium, a lipid found in synaptic vesicles and cholesterol, serves a role in metabolic research [1].Formula:C42H79NNaO10PColor and Shape:SolidMolecular weight:812.0418-Hydroxycorticosterone
CAS:18-Hydroxycorticosterone is a corticosteroid and corticosterone derivative, which can lead to serious electrolyte imbalances.Formula:C21H30O5Purity:98%Color and Shape:SolidMolecular weight:362.46Trihydroxycholestanoic Acid
CAS:Trihydroxycholestanoic acid aids cholic acid creation; high levels indicate Zellweger syndrome due to faulty PEX genes.
Formula:C27H46O5Color and Shape:SolidMolecular weight:450.66(Ile8)-Oxytocin acetate
(Ile8)-Oxytocin acetate is a neurohypophysial hormone analog of oxytocin produced in marsupials.Formula:C45H70N12O14S2Color and Shape:SolidMolecular weight:1067.24hCAI/II-IN-10
hCAI/II-IN-10 (Compound 5d) is an inhibitor of human carbonic anhydrase I and II (hCA I and hCA II), with IC50 values of 4.32 nM and 3.89 nM, respectively.Formula:C24H17Cl2N3O3S2Color and Shape:SolidMolecular weight:530.446Glycerol kinase
CAS:GyK, a bacterial sugar kinase, initiates glycerol metabolism by converting it into G3P, key for cell uptake.Color and Shape:SolidPlipastatin A1
CAS:Plipastatin A1, a lipopeptide isolated from B.Formula:C72H110N12O20Color and Shape:SolidMolecular weight:1463.71
