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Metabolism

Metabolism

Metabolism inhibitors are compounds that interfere with metabolic pathways, altering the production and utilization of energy within cells. These inhibitors are used to study the regulation of metabolism, the role of metabolic pathways in diseases like cancer and diabetes, and to develop new therapeutic strategies. Metabolism inhibitors can target various enzymes and processes involved in glycolysis, fatty acid oxidation, and other metabolic functions. At CymitQuimica, we offer a wide range of high-quality metabolism inhibitors to support your research in biochemistry, metabolic disorders, and drug development.

Subcategories of "Metabolism"

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Found 9195 products of "Metabolism"

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  • α-Glycerophosphate Dehydrogenase-Triosephosphate


    α-Glycerophosphate Dehydrogenase-Triosephosphate (GDH-TIM) is an enzyme mixture composed of glycerophosphate dehydrogenase (GDH) and triosephosphate isomerase (TIM). This compound is employed to measure transketolase (TK) activity in erythrocyte hemolysates, which helps in assessing vitamin B deficiency.

    Ref: TM-TRP-00343

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  • Carbonic anhydrase inhibitor 18


    Carbonic anhydrase inhibitor18 (Compound 9) is an inhibitor of human carbonic anhydrase (hCA) isozymes, with Ki values of 604.8 nM for hCA I, 333.6 nM for hCA II, 1.9 nM for hCA IX, and 6.7 nM for hCA XII. Carbonic anhydrase inhibitor18 is applicable in cancer research.
    Formula:C26H28N4O6S2
    Molecular weight:556.14503

    Ref: TM-TYD-02782

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  • α-Glucosidase-IN-55


    α-Glucosidase-IN-55 (Compound 8g) is an orally active, competitive inhibitor of α-glucosidase with an IC50 value of 12.1 µM and a Ki value of 9.66 µM. It is useful for research related to Type 2 Diabetes Mellitus (T2DM), as it can enhance glycemic control and metabolic health.
    Formula:C31H22ClN3S
    Molecular weight:503.1223

    Ref: TM-T209525

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  • α-Amylase/α-Glucosidase-IN-14


    α-Amylase/α-Glucosidase-IN-14 is an orally bioactive inhibitor of α-amylase and α-glucosidase, with IC50 values of 45.53 μM and 27.73 μM, respectively.
    Formula:C24H19FN4O2S
    Molecular weight:446.12128

    Ref: TM-T210057

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  • α-Amylase/α-Glucosidase-IN-9


    α-Amylase/α-Glucosidase-IN-9 (compound 5h) is a dual inhibitor of α-amylase (IC50= 16.4 μM) and α-glucosidase (IC50= 31.6 μM).
    Formula:C20H16ClN5O4
    Molecular weight:425.08908

    Ref: TM-T209500

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  • α-Amylase/α-Glucosidase-IN-15


    α-Amylase/α-Glucosidase-IN-15 (compound 6C) is an orally active inhibitor of α-glucosidase (α-Glucosidase) and α-amylase (α-amylase), with IC50 values of 21 μM and 61 μM, respectively.
    Formula:C26H24N4O3S
    Molecular weight:472.15691

    Ref: TM-T210372

    10mg
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  • Carbonic anhydrase/AChE-IN-2


    Carbonic anhydrase/AChE-IN-2 (compound 19) is a selective inhibitor of acetylcholinesterase (AChE) and carbonic anhydrase (CA), with inhibition efficiencies (Ei) of 8.54 nM, 13.54 nM, and 5.21 nM, respectively.
    Formula:C17H12BrF3O2
    Molecular weight:383.99728

    Ref: TM-T209031

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  • ST6 Sialyltransferase 5


    ST6Sialyltransferase5 (EC:2.4.3.3, ST6GALNAC5, SIAT7E, ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5) transfers sialic acid to N-acetylgalactosamine (GalNAc) residues. It may serve as a biomarker in cervical screening samples.

    Ref: TM-TRP-00426

    10mg
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  • NAMPT activator-7


    NAMPTactivator-7 (Compound 232) is an activator of nicotinamide phosphoribosyltransferase (NAMPT) with an EC50 of less than 0.5 μM. It effectively stimulates NAMPT in U2OS cells, demonstrating a cellular EC50 of less than 0.5 μM.
    Formula:C21H17ClN4O3
    Molecular weight:408.09892

    Ref: TM-T209665

    10mg
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  • GZ22-4


    GZ22-4 is a near-infrared (NIR) fluorescent probe with a high affinity for carbonic anhydrase IX (CAIX), exhibiting a dissociation constant (Kd) of 0.2 nM. It is applicable in studies for visualizing CAIX-positive tumors.
    Formula:C88H126F3N6NaO24S4
    Molecular weight:1858.75561

    Ref: TM-T209836

    10mg
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  • FXIIa-IN-4


    FXIIa-IN-4 (compound 22) is a potent and selective human FXIIa inhibitor, exhibiting IC50 values of 0.032 μM for FXIIa, 0.30 μM for thrombin, and >50 μM for FXIa. It is utilized in anticoagulant research.
    Formula:C11H9FN4O3
    Molecular weight:264.06587

    Ref: TM-T210411

    10mg
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  • LTA4H-IN-4


    LTA4H-IN-4 (compound 3) is an orally active inhibitor of LTA4H. It exhibits an IC50 value of 156 μM against hERG and is applicable for inflammation-related research.

    Ref: TM-T207847

    10mg
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  • Antibacterial agent 218


    Antibacterialagent 218 (compound d28) is an orally active inhibitor of sterol 24-C-methyltransferase with an IC50 value of 0.273 μM. It also displays antifungal activity against Candida albicans SC5314, with an IC50 of 0.25 μg/mL.
    Formula:C30H24N4OS
    Molecular weight:488.16708

    Ref: TM-T210190

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  • α-Glucosidase-IN-49


    α-Glucosidase-IN-49 (compound C23) is a potent inhibitor of α-Glucosidase, with an IC50 of 0.52 μM. This compound exhibits oral bioactivity, effectively lowering blood glucose levels and enhancing glucose tolerance in mice.
    Formula:C21H13F3N4O3S3
    Molecular weight:522.01019

    Ref: TM-T209076

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  • hCAIX/XII-IN-11


    hCAIX/XII-IN-11 (Compound 6c) is an inhibitor of hCA IX and hCA XII, exhibiting Ki values of 0.7 μM for both isoforms. This compound is applicable in cancer research.
    Formula:C13H10FN3O4
    Molecular weight:291.06553

    Ref: TM-TYD-02783

    10mg
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  • Transketolase-IN-6


    Transketolase-IN-6 (Compound 6bj) serves as a lead compound for herbicides. It achieves approximately 80% root inhibition in redroot pigweed (Amaranthus retroflexus) and green foxtail (Setaria viridis). Moreover, Transketolase-IN-6 is an effective inhibitor of transketolase (TK).
    Formula:C23H27ClN6O
    Molecular weight:438.19349

    Ref: TM-T209243

    10mg
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  • α-Glucosidase-IN-67


    α-Glucosidase-IN-67 (compound 5k) is a potent inhibitor of α-glucosidase, exhibiting IC50 values of 0.31 µM for α-glucosidase and 4.51 µM for α-amylase. This compound shows potential for research in type 2 diabetes.
    Formula:C24H22BrN3O3S
    Molecular weight:511.05653

    Ref: TM-T210381

    10mg
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  • Human Factor VIIa


    HumanFactor VIIa is a vitamin K-dependent serine protease involved in the blood coagulation process. It has the ability to activate coagulation factor X, which in turn converts prothrombin into thrombin, leading to the transformation of fibrinogen into fibrin and resulting in the formation of blood clots. HumanFactor VIIa holds potential for improving hemophilia.

    Ref: TM-TRP-00471

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  • α-Amylase/α-Glucosidase-IN-11


    α-Amylase/α-Glucosidase-IN-11 (Compound 5d) is an isoxazoline-indigo hybrid with notable antidiabetic properties. It acts as a competitive inhibitor of the key digestive enzymes α-amylase (IC50 = 30.39 μM) and α-glucosidase (IC50 = 65.1 μM). Additionally, it does not penetrate the blood-brain barrier.
    Formula:C33H40ClN5O5
    Molecular weight:621.2718

    Ref: TM-T209711

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  • MPO-IN-6


    MPO-IN-6 (compound ADC) is an electrophilic agent with excellent antioxidant and anti-inflammatory properties. It acts as an inhibitor of myeloperoxidase (MPO), dipeptidyl peptidase-4 (DPP-4), and α-glucosidase (α-GD), with IC50 values of 10 μM, 31.02 μM, and 46.05 μM, respectively. MPO-IN-6 may serve as a potential cardiovascular protective agent.
    Formula:C16H12N2O6
    Molecular weight:328.06954

    Ref: TM-T209254

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  • α-Glucosidase-IN-57


    α-Glucosidase-IN-57 (Compound 10c) is a competitive, orally active α-glucosidase inhibitor with an IC50 of 0.180 μM and a Ki of 0.15 μM. It effectively reduces fasting and overall blood glucose levels in mice, making it suitable for antidiabetic research.
    Formula:C32H23FN4OS
    Molecular weight:530.15766

    Ref: TM-T209503

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  • α-Glucosidase-IN-58


    α-Glucosidase-IN-58 (Compound 6d) is an α-glucosidase inhibitor with an IC50 of 1.47 μM.
    Formula:C22H13F3N2OS
    Molecular weight:410.07007

    Ref: TM-T209494

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  • Butyryl-Coenzyme A trisodium


    Butyryl-Coenzyme A (trisodium) is a microbial metabolite that can be synthesized into butyric acid or butyrate.
    Formula:C25H39N7Na3O17P3S
    Molecular weight:903.10291

    Ref: TM-TYD-02789

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  • PR280


    PR280 is a potent inhibitor of dihydroceramide desaturase 1 (Des1) with an IC50 of 700 nM. It forms hydrogen bonds with amino acid residues of Des1, while its cyclopropenone group may coordinate with the iron center, stabilizing its binding at Des1's active site. This inhibits the ceramide biosynthesis pathway, preventing dihydroceramide (dhCer) from converting into ceramide. PR280 can be used in research related to sphingolipid metabolism disorders, including cancer and metabolic diseases.

    Formula:C27H49NO4
    Molecular weight:451.36616

    Ref: TM-T210078

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  • C16 Lactosylceramide (d18:1/16:0)

    CAS:
    C16 Lactosylceramide, a sphingolipid, modulates cell signaling and is high in insulin-resistant cattle and Niemann-Pick type C1 disease.
    Formula:C46H87NO13
    Color and Shape:Solid
    Molecular weight:862.18

    Ref: TM-T35804

    1mg
    1,069.00€
    5mg
    2,312.00€
  • Thalifendine chloride

    CAS:
    Thalifendine chloride is a metabolite of berberine,the methoxy group at the C-10 position undergoes demethylation by CYP51. cytotoxicity against P-388 cells.
    Formula:C19H16ClNO4
    Color and Shape:Solid
    Molecular weight:357.79

    Ref: TM-T75640

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  • Neogen

    CAS:
    Neogen, also known as Jadinol PU, is a drug potentially for the restoration of the immune system and hemopoiesis after cytostatics treatment.
    Formula:C22H30N4O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:446.50

    Ref: TM-T28155

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  • AUPF02

    CAS:
    AUPF02, a 5-aryluracil derivative, is an effective anti-breast cancer compound with an IC50 value of 23.4 µM against MCF-7 cells.
    Formula:C14H9F5N2O
    Color and Shape:Solid
    Molecular weight:316.23

    Ref: TM-T203463

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  • EDDA

    CAS:
    Ethylenediaminediacetic acid is derived from two molecules of glycine linked by amines.
    Formula:C6H12N2O4
    Color and Shape:Solid
    Molecular weight:176.17

    Ref: TM-T21207

    25mg
    1,369.00€
  • Triornicin

    CAS:
    Triornicin is a siderophore and tumor inhibitory factor isolated from Epicoccum purpurascens similar in structure to desferricoprogen.
    Formula:C31H50N6O12
    Purity:98%
    Color and Shape:Solid
    Molecular weight:698.76

    Ref: TM-T26294

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  • Deoxyadenosine diphosphate sodium

    CAS:
    Deoxyadenosine diphosphate sodium is a diphosphate nucleoside featuring deoxyadenosine as its nucleoside component. It plays a role in the synthesis and repair of DNA. Deoxyadenosine diphosphate sodium acts as an inhibitor of polynucleotide phosphorylase, thereby interfering with the polymerization of ADP and CDP.
    Formula:C10H12N5Na3O9P2
    Color and Shape:Solid
    Molecular weight:477.15

    Ref: TM-T203490

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  • Cyperine

    CAS:
    Cyperine is a useful organic compound for research related to life sciences. The catalog number is T125020 and the CAS number is 33716-82-4.
    Formula:C15H16O4
    Color and Shape:Solid
    Molecular weight:260.289

    Ref: TM-T125020

    1mg
    673.00€
  • Triethyl phosphate

    CAS:
    Triethyl phosphate is a chemical compound. It can be called "phosphoric acid, triethyl ester".
    Formula:C6H15O4P
    Purity:98%
    Color and Shape:Clear Liquid
    Molecular weight:182.16

    Ref: TM-T20288

    25mg
    1,369.00€
  • 2,3,4,6,7,8-Hexachlorodibenzofuran

    CAS:
    2,3,4,6,7,8-Hexachlorodibenzofuran (2,3,4,6,7,8-HxCDF) is a type of polychlorinated dibenzofuran (PCDF). It induces the expression of aryl hydrocarbon hydroxylase (AHH) and ethoxyresorufin-o-deethylase (EROD) genes in H-4-II-E rat hepatoma cells, with EC50 values of 0.687 and 0.575 nM, respectively.
    Formula:C12H2Cl6O
    Color and Shape:Solid
    Molecular weight:374.86

    Ref: TM-T203593

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  • FR106969

    CAS:
    FR106969 is a platelet activating factor antagonist isolated from fungus with anti-inflammatory activity.
    Formula:C16H22N2O3S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:354.49

    Ref: TM-T27370

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  • Leucomyosuppressin

    CAS:
    Leucomyosuppressin, isolated from head extracts of the cockroach Leucophaea maderae, inhibits evoked transmitter release at the mealworm neuromuscular junction.
    Formula:C59H84N16O15
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1257.418

    Ref: TM-T25683

    25mg
    1,369.00€
  • Ciwujianoside D2

    CAS:
    Ciwujianoside D2 is a useful organic compound for research related to life sciences. The catalog number is T126336 and the CAS number is 114892-57-8.
    Formula:C54H84O22
    Color and Shape:Solid
    Molecular weight:1085.24

    Ref: TM-T126336

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  • Fluazuron

    CAS:
    Fluazuron is an insect growth regulator.
    Formula:C20H10Cl2F5N3O3
    Color and Shape:White Powder
    Molecular weight:506.21

    Ref: TM-T27339

    1g
    1,648.00€
    250mg
    462.00€
    500mg
    880.00€
  • BtGH84 Activator I

    CAS:
    BtGH84 Activator I is a BtGH84 activator. It is the small molecule activator of a glycoside hydrolase.
    Formula:C10H10N2O
    Color and Shape:Solid
    Molecular weight:174.20

    Ref: TM-T23828

    25mg
    1,369.00€
  • N,N'-Diacetyl-L-cystine

    CAS:
    DiNAC is a disulphide dimer with immune-modulating effects and reduces atherosclerosis in WHHL rabbits; also modulates rodent sensitivity reactions.
    Formula:C10H16N2O6S2
    Purity:98.76%
    Color and Shape:White Powder
    Molecular weight:324.37

    Ref: TM-T16240

    200mg
    37.00€
    500mg
    57.00€
    1mL*10mM (DMSO)
    33.00€
  • Evinacumab

    CAS:
    Evinacumab (REGN1500) is a humanized monoclonal antibody targeting ANGPTL3. It is useful for studying cardiovascular diseases.
    Purity:100% (SEC-HPLC) - 99.43% (SEC-HPLC)
    Color and Shape:Liquid
    Molecular weight:150 kDa

    Ref: TM-T77492

    1mg
    362.00€
    5mg
    952.00€
    10mg
    1,276.00€
    25mg
    1,839.00€
    50mg
    2,489.00€
  • SLC7A11-IN-3


    SLC7A11-IN-3 (Compound 42711_11) acts as an inhibitor of SLC7A11.
    Color and Shape:Odour Solid

    Ref: TM-T200563

    10mg
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  • Folitixorin calcium

    CAS:
    Folitixorin calcium is an antineoplastic enhancing agent.
    Formula:C20H25CaN7O6
    Color and Shape:Solid
    Molecular weight:499.541

    Ref: TM-T25435

    25mg
    3,150.00€
    50mg
    4,438.00€
    100mg
    6,238.00€
  • Lipstatin

    CAS:
    Lipstatin is a potent inhibitor of the pancreas lipase. It is reported to be useful in the treatment and/or prevention of obesity and related diseases.
    Formula:C29H49NO5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:491.7

    Ref: TM-T20441

    25mg
    1,369.00€
  • Campestanol

    CAS:
    Campestanol is a natural plant sterol from Brassica campestris.
    Formula:C28H50O
    Color and Shape:Solid
    Molecular weight:402.71

    Ref: TM-T21255

    500µg
    482.00€
  • PDE1-IN-8


    PDE1-IN-8 (Compound 3f) acts as an inhibitor of PDE1, with an IC50 of 11 nM. It hinders cAMP and cGMP signaling pathways, impeding the differentiation and proliferation of cells into myofibroblasts, and demonstrates antifibrotic effects in the Bleomycin-induced rat model of pulmonary fibrosis.
    Formula:C17H11Cl2N3OS2
    Color and Shape:Solid
    Molecular weight:408.32

    Ref: TM-T203453

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  • Tetrahydropteroylpentaglutamate

    CAS:
    H4PteGlu5 strongly inhibits itself and tightly binds in vivo, almost irreversibly, as a coenzyme.
    Formula:C39H51N11O18
    Purity:98%
    Color and Shape:Solid
    Molecular weight:961.89

    Ref: TM-T26262

    25mg
    1,369.00€
  • BVT-2733 hydrochloride

    CAS:
    BVT-2733 hydrochloride is a potent, selective, and orally active non-steroidal 11β-HSD1 inhibitor. It exhibits stronger inhibition on mouse 11β-HSD1 enzyme (IC50=96 nM) compared to the human 11β-HSD1 enzyme (IC50=3341 nM). BVT-2733 hydrochloride shows potential for research in arthritis and obesity-related diseases.
    Formula:C17H22Cl2N4O3S2
    Color and Shape:Solid
    Molecular weight:465.42

    Ref: TM-T203621

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  • DJ-53


    DJ-53 (compound 68) is an orally active, phenyl-quinoline-based soluble epoxide hydrolase inhibitor.
    Color and Shape:Odour Solid

    Ref: TM-T200655

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  • Osmanthuside H

    CAS:
    Osmanthuside H is a useful organic compound for research related to life sciences. The catalog number is T125796 and the CAS number is 149155-70-4.
    Formula:C19H28O11
    Color and Shape:Solid
    Molecular weight:432.422

    Ref: TM-T125796

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