Metabolism
Metabolism inhibitors are compounds that interfere with metabolic pathways, altering the production and utilization of energy within cells. These inhibitors are used to study the regulation of metabolism, the role of metabolic pathways in diseases like cancer and diabetes, and to develop new therapeutic strategies. Metabolism inhibitors can target various enzymes and processes involved in glycolysis, fatty acid oxidation, and other metabolic functions. At CymitQuimica, we offer a wide range of high-quality metabolism inhibitors to support your research in biochemistry, metabolic disorders, and drug development.
Subcategories of "Metabolism"
- AhR(42 products)
- Aminopeptidase(76 products)
- CETP(20 products)
- Carbonic Anhydrase(196 products)
- Casein Kinase(139 products)
- DHFR(30 products)
- Decarboxylase(4 products)
- Dehydrogenase(302 products)
- FAAH(64 products)
- FXR(62 products)
- Factor Xa(87 products)
- Fatty Acid Synthase(37 products)
- Ferroptosis(227 products)
- GR(3 products)
- GSNOR(3 products)
- Glucokinase(56 products)
- HIF/HIF Prolyl-Hydroxylase(146 products)
- HMG-CoA Reductase(34 products)
- Hydroxylase(36 products)
- IDO(84 products)
- LDL(7 products)
- Lipase(107 products)
- Lipid(62 products)
- Lipoxygenase(133 products)
- MAO(85 products)
- MPO(2 products)
- NAMPT(40 products)
- P450(6 products)
- PAI-1(26 products)
- PDE(170 products)
- PED(1 products)
- PKM(17 products)
- PPAR(170 products)
- Phospholipase(85 products)
- ROR(47 products)
- Retinoid Receptor(18 products)
- SGK(10 products)
- Thioredoxin(12 products)
- Transferase(30 products)
- Transporter(43 products)
- UGT(4 products)
- Xanthine Oxidase (XO) Inhibitors(9 products)
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Found 9195 products of "Metabolism"
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α-Glycerophosphate Dehydrogenase-Triosephosphate
α-Glycerophosphate Dehydrogenase-Triosephosphate (GDH-TIM) is an enzyme mixture composed of glycerophosphate dehydrogenase (GDH) and triosephosphate isomerase (TIM). This compound is employed to measure transketolase (TK) activity in erythrocyte hemolysates, which helps in assessing vitamin B deficiency.Carbonic anhydrase inhibitor 18
Carbonic anhydrase inhibitor18 (Compound 9) is an inhibitor of human carbonic anhydrase (hCA) isozymes, with Ki values of 604.8 nM for hCA I, 333.6 nM for hCA II, 1.9 nM for hCA IX, and 6.7 nM for hCA XII. Carbonic anhydrase inhibitor18 is applicable in cancer research.Formula:C26H28N4O6S2Molecular weight:556.14503α-Glucosidase-IN-55
α-Glucosidase-IN-55 (Compound 8g) is an orally active, competitive inhibitor of α-glucosidase with an IC50 value of 12.1 µM and a Ki value of 9.66 µM. It is useful for research related to Type 2 Diabetes Mellitus (T2DM), as it can enhance glycemic control and metabolic health.Formula:C31H22ClN3SMolecular weight:503.1223α-Amylase/α-Glucosidase-IN-14
α-Amylase/α-Glucosidase-IN-14 is an orally bioactive inhibitor of α-amylase and α-glucosidase, with IC50 values of 45.53 μM and 27.73 μM, respectively.Formula:C24H19FN4O2SMolecular weight:446.12128α-Amylase/α-Glucosidase-IN-9
α-Amylase/α-Glucosidase-IN-9 (compound 5h) is a dual inhibitor of α-amylase (IC50= 16.4 μM) and α-glucosidase (IC50= 31.6 μM).Formula:C20H16ClN5O4Molecular weight:425.08908α-Amylase/α-Glucosidase-IN-15
α-Amylase/α-Glucosidase-IN-15 (compound 6C) is an orally active inhibitor of α-glucosidase (α-Glucosidase) and α-amylase (α-amylase), with IC50 values of 21 μM and 61 μM, respectively.Formula:C26H24N4O3SMolecular weight:472.15691Carbonic anhydrase/AChE-IN-2
Carbonic anhydrase/AChE-IN-2 (compound 19) is a selective inhibitor of acetylcholinesterase (AChE) and carbonic anhydrase (CA), with inhibition efficiencies (Ei) of 8.54 nM, 13.54 nM, and 5.21 nM, respectively.Formula:C17H12BrF3O2Molecular weight:383.99728ST6 Sialyltransferase 5
ST6Sialyltransferase5 (EC:2.4.3.3, ST6GALNAC5, SIAT7E, ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5) transfers sialic acid to N-acetylgalactosamine (GalNAc) residues. It may serve as a biomarker in cervical screening samples.NAMPT activator-7
NAMPTactivator-7 (Compound 232) is an activator of nicotinamide phosphoribosyltransferase (NAMPT) with an EC50 of less than 0.5 μM. It effectively stimulates NAMPT in U2OS cells, demonstrating a cellular EC50 of less than 0.5 μM.Formula:C21H17ClN4O3Molecular weight:408.09892GZ22-4
GZ22-4 is a near-infrared (NIR) fluorescent probe with a high affinity for carbonic anhydrase IX (CAIX), exhibiting a dissociation constant (Kd) of 0.2 nM. It is applicable in studies for visualizing CAIX-positive tumors.Formula:C88H126F3N6NaO24S4Molecular weight:1858.75561FXIIa-IN-4
FXIIa-IN-4 (compound 22) is a potent and selective human FXIIa inhibitor, exhibiting IC50 values of 0.032 μM for FXIIa, 0.30 μM for thrombin, and >50 μM for FXIa. It is utilized in anticoagulant research.Formula:C11H9FN4O3Molecular weight:264.06587LTA4H-IN-4
LTA4H-IN-4 (compound 3) is an orally active inhibitor of LTA4H. It exhibits an IC50 value of 156 μM against hERG and is applicable for inflammation-related research.Antibacterial agent 218
Antibacterialagent 218 (compound d28) is an orally active inhibitor of sterol 24-C-methyltransferase with an IC50 value of 0.273 μM. It also displays antifungal activity against Candida albicans SC5314, with an IC50 of 0.25 μg/mL.Formula:C30H24N4OSMolecular weight:488.16708α-Glucosidase-IN-49
α-Glucosidase-IN-49 (compound C23) is a potent inhibitor of α-Glucosidase, with an IC50 of 0.52 μM. This compound exhibits oral bioactivity, effectively lowering blood glucose levels and enhancing glucose tolerance in mice.Formula:C21H13F3N4O3S3Molecular weight:522.01019hCAIX/XII-IN-11
hCAIX/XII-IN-11 (Compound 6c) is an inhibitor of hCA IX and hCA XII, exhibiting Ki values of 0.7 μM for both isoforms. This compound is applicable in cancer research.Formula:C13H10FN3O4Molecular weight:291.06553Transketolase-IN-6
Transketolase-IN-6 (Compound 6bj) serves as a lead compound for herbicides. It achieves approximately 80% root inhibition in redroot pigweed (Amaranthus retroflexus) and green foxtail (Setaria viridis). Moreover, Transketolase-IN-6 is an effective inhibitor of transketolase (TK).Formula:C23H27ClN6OMolecular weight:438.19349α-Glucosidase-IN-67
α-Glucosidase-IN-67 (compound 5k) is a potent inhibitor of α-glucosidase, exhibiting IC50 values of 0.31 µM for α-glucosidase and 4.51 µM for α-amylase. This compound shows potential for research in type 2 diabetes.Formula:C24H22BrN3O3SMolecular weight:511.05653Human Factor VIIa
HumanFactor VIIa is a vitamin K-dependent serine protease involved in the blood coagulation process. It has the ability to activate coagulation factor X, which in turn converts prothrombin into thrombin, leading to the transformation of fibrinogen into fibrin and resulting in the formation of blood clots. HumanFactor VIIa holds potential for improving hemophilia.α-Amylase/α-Glucosidase-IN-11
α-Amylase/α-Glucosidase-IN-11 (Compound 5d) is an isoxazoline-indigo hybrid with notable antidiabetic properties. It acts as a competitive inhibitor of the key digestive enzymes α-amylase (IC50 = 30.39 μM) and α-glucosidase (IC50 = 65.1 μM). Additionally, it does not penetrate the blood-brain barrier.Formula:C33H40ClN5O5Molecular weight:621.2718MPO-IN-6
MPO-IN-6 (compound ADC) is an electrophilic agent with excellent antioxidant and anti-inflammatory properties. It acts as an inhibitor of myeloperoxidase (MPO), dipeptidyl peptidase-4 (DPP-4), and α-glucosidase (α-GD), with IC50 values of 10 μM, 31.02 μM, and 46.05 μM, respectively. MPO-IN-6 may serve as a potential cardiovascular protective agent.Formula:C16H12N2O6Molecular weight:328.06954α-Glucosidase-IN-57
α-Glucosidase-IN-57 (Compound 10c) is a competitive, orally active α-glucosidase inhibitor with an IC50 of 0.180 μM and a Ki of 0.15 μM. It effectively reduces fasting and overall blood glucose levels in mice, making it suitable for antidiabetic research.Formula:C32H23FN4OSMolecular weight:530.15766α-Glucosidase-IN-58
α-Glucosidase-IN-58 (Compound 6d) is an α-glucosidase inhibitor with an IC50 of 1.47 μM.Formula:C22H13F3N2OSMolecular weight:410.07007Butyryl-Coenzyme A trisodium
Butyryl-Coenzyme A (trisodium) is a microbial metabolite that can be synthesized into butyric acid or butyrate.Formula:C25H39N7Na3O17P3SMolecular weight:903.10291PR280
PR280 is a potent inhibitor of dihydroceramide desaturase 1 (Des1) with an IC50 of 700 nM. It forms hydrogen bonds with amino acid residues of Des1, while its cyclopropenone group may coordinate with the iron center, stabilizing its binding at Des1's active site. This inhibits the ceramide biosynthesis pathway, preventing dihydroceramide (dhCer) from converting into ceramide. PR280 can be used in research related to sphingolipid metabolism disorders, including cancer and metabolic diseases.
Formula:C27H49NO4Molecular weight:451.36616C16 Lactosylceramide (d18:1/16:0)
CAS:C16 Lactosylceramide, a sphingolipid, modulates cell signaling and is high in insulin-resistant cattle and Niemann-Pick type C1 disease.Formula:C46H87NO13Color and Shape:SolidMolecular weight:862.18Thalifendine chloride
CAS:Thalifendine chloride is a metabolite of berberine,the methoxy group at the C-10 position undergoes demethylation by CYP51. cytotoxicity against P-388 cells.Formula:C19H16ClNO4Color and Shape:SolidMolecular weight:357.79Neogen
CAS:Neogen, also known as Jadinol PU, is a drug potentially for the restoration of the immune system and hemopoiesis after cytostatics treatment.Formula:C22H30N4O6Purity:98%Color and Shape:SolidMolecular weight:446.50AUPF02
CAS:AUPF02, a 5-aryluracil derivative, is an effective anti-breast cancer compound with an IC50 value of 23.4 µM against MCF-7 cells.Formula:C14H9F5N2OColor and Shape:SolidMolecular weight:316.23EDDA
CAS:Ethylenediaminediacetic acid is derived from two molecules of glycine linked by amines.Formula:C6H12N2O4Color and Shape:SolidMolecular weight:176.17Triornicin
CAS:Triornicin is a siderophore and tumor inhibitory factor isolated from Epicoccum purpurascens similar in structure to desferricoprogen.Formula:C31H50N6O12Purity:98%Color and Shape:SolidMolecular weight:698.76Deoxyadenosine diphosphate sodium
CAS:Deoxyadenosine diphosphate sodium is a diphosphate nucleoside featuring deoxyadenosine as its nucleoside component. It plays a role in the synthesis and repair of DNA. Deoxyadenosine diphosphate sodium acts as an inhibitor of polynucleotide phosphorylase, thereby interfering with the polymerization of ADP and CDP.Formula:C10H12N5Na3O9P2Color and Shape:SolidMolecular weight:477.15Cyperine
CAS:Cyperine is a useful organic compound for research related to life sciences. The catalog number is T125020 and the CAS number is 33716-82-4.Formula:C15H16O4Color and Shape:SolidMolecular weight:260.289Triethyl phosphate
CAS:Triethyl phosphate is a chemical compound. It can be called "phosphoric acid, triethyl ester".Formula:C6H15O4PPurity:98%Color and Shape:Clear LiquidMolecular weight:182.162,3,4,6,7,8-Hexachlorodibenzofuran
CAS:2,3,4,6,7,8-Hexachlorodibenzofuran (2,3,4,6,7,8-HxCDF) is a type of polychlorinated dibenzofuran (PCDF). It induces the expression of aryl hydrocarbon hydroxylase (AHH) and ethoxyresorufin-o-deethylase (EROD) genes in H-4-II-E rat hepatoma cells, with EC50 values of 0.687 and 0.575 nM, respectively.Formula:C12H2Cl6OColor and Shape:SolidMolecular weight:374.86FR106969
CAS:FR106969 is a platelet activating factor antagonist isolated from fungus with anti-inflammatory activity.Formula:C16H22N2O3S2Purity:98%Color and Shape:SolidMolecular weight:354.49Leucomyosuppressin
CAS:Leucomyosuppressin, isolated from head extracts of the cockroach Leucophaea maderae, inhibits evoked transmitter release at the mealworm neuromuscular junction.Formula:C59H84N16O15Purity:98%Color and Shape:SolidMolecular weight:1257.418Ciwujianoside D2
CAS:Ciwujianoside D2 is a useful organic compound for research related to life sciences. The catalog number is T126336 and the CAS number is 114892-57-8.Formula:C54H84O22Color and Shape:SolidMolecular weight:1085.24Fluazuron
CAS:Fluazuron is an insect growth regulator.Formula:C20H10Cl2F5N3O3Color and Shape:White PowderMolecular weight:506.21BtGH84 Activator I
CAS:BtGH84 Activator I is a BtGH84 activator. It is the small molecule activator of a glycoside hydrolase.Formula:C10H10N2OColor and Shape:SolidMolecular weight:174.20N,N'-Diacetyl-L-cystine
CAS:DiNAC is a disulphide dimer with immune-modulating effects and reduces atherosclerosis in WHHL rabbits; also modulates rodent sensitivity reactions.Formula:C10H16N2O6S2Purity:98.76%Color and Shape:White PowderMolecular weight:324.37Evinacumab
CAS:Evinacumab (REGN1500) is a humanized monoclonal antibody targeting ANGPTL3. It is useful for studying cardiovascular diseases.Purity:100% (SEC-HPLC) - 99.43% (SEC-HPLC)Color and Shape:LiquidMolecular weight:150 kDaSLC7A11-IN-3
SLC7A11-IN-3 (Compound 42711_11) acts as an inhibitor of SLC7A11.Color and Shape:Odour SolidFolitixorin calcium
CAS:Folitixorin calcium is an antineoplastic enhancing agent.Formula:C20H25CaN7O6Color and Shape:SolidMolecular weight:499.541Lipstatin
CAS:Lipstatin is a potent inhibitor of the pancreas lipase. It is reported to be useful in the treatment and/or prevention of obesity and related diseases.Formula:C29H49NO5Purity:98%Color and Shape:SolidMolecular weight:491.7Campestanol
CAS:Campestanol is a natural plant sterol from Brassica campestris.Formula:C28H50OColor and Shape:SolidMolecular weight:402.71PDE1-IN-8
PDE1-IN-8 (Compound 3f) acts as an inhibitor of PDE1, with an IC50 of 11 nM. It hinders cAMP and cGMP signaling pathways, impeding the differentiation and proliferation of cells into myofibroblasts, and demonstrates antifibrotic effects in the Bleomycin-induced rat model of pulmonary fibrosis.Formula:C17H11Cl2N3OS2Color and Shape:SolidMolecular weight:408.32Tetrahydropteroylpentaglutamate
CAS:H4PteGlu5 strongly inhibits itself and tightly binds in vivo, almost irreversibly, as a coenzyme.Formula:C39H51N11O18Purity:98%Color and Shape:SolidMolecular weight:961.89BVT-2733 hydrochloride
CAS:BVT-2733 hydrochloride is a potent, selective, and orally active non-steroidal 11β-HSD1 inhibitor. It exhibits stronger inhibition on mouse 11β-HSD1 enzyme (IC50=96 nM) compared to the human 11β-HSD1 enzyme (IC50=3341 nM). BVT-2733 hydrochloride shows potential for research in arthritis and obesity-related diseases.Formula:C17H22Cl2N4O3S2Color and Shape:SolidMolecular weight:465.42DJ-53
DJ-53 (compound 68) is an orally active, phenyl-quinoline-based soluble epoxide hydrolase inhibitor.Color and Shape:Odour SolidOsmanthuside H
CAS:Osmanthuside H is a useful organic compound for research related to life sciences. The catalog number is T125796 and the CAS number is 149155-70-4.Formula:C19H28O11Color and Shape:SolidMolecular weight:432.422
