Metabolism
Metabolism inhibitors are compounds that interfere with metabolic pathways, altering the production and utilization of energy within cells. These inhibitors are used to study the regulation of metabolism, the role of metabolic pathways in diseases like cancer and diabetes, and to develop new therapeutic strategies. Metabolism inhibitors can target various enzymes and processes involved in glycolysis, fatty acid oxidation, and other metabolic functions. At CymitQuimica, we offer a wide range of high-quality metabolism inhibitors to support your research in biochemistry, metabolic disorders, and drug development.
Subcategories of "Metabolism"
- AhR(42 products)
- Aminopeptidase(76 products)
- CETP(20 products)
- Carbonic Anhydrase(196 products)
- Casein Kinase(138 products)
- DHFR(30 products)
- Decarboxylase(4 products)
- Dehydrogenase(301 products)
- FAAH(64 products)
- FXR(62 products)
- Factor Xa(85 products)
- Fatty Acid Synthase(37 products)
- Ferroptosis(226 products)
- GR(3 products)
- GSNOR(3 products)
- Glucokinase(57 products)
- HIF/HIF Prolyl-Hydroxylase(146 products)
- HMG-CoA Reductase(34 products)
- Hydroxylase(36 products)
- IDO(84 products)
- LDL(7 products)
- Lipase(107 products)
- Lipid(61 products)
- Lipoxygenase(133 products)
- MAO(87 products)
- MPO(2 products)
- NAMPT(40 products)
- P450(6 products)
- PAI-1(26 products)
- PDE(169 products)
- PED(1 products)
- PKM(17 products)
- PPAR(170 products)
- Phospholipase(86 products)
- ROR(47 products)
- Retinoid Receptor(20 products)
- SGK(10 products)
- Thioredoxin(12 products)
- Transferase(29 products)
- Transporter(44 products)
- UGT(4 products)
- Xanthine Oxidase (XO) Inhibitors(9 products)
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Found 9154 products of "Metabolism"
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Phospho-L-arginine
CAS:Phospho-L-arginine is a derivative of arginine.Formula:C6H15N4O5PMolecular weight:254.18L 691816
CAS:L 691816 is an effective inhibitor of the 5-LO reaction.Formula:C36H35ClN6OSPurity:98%Color and Shape:SolidMolecular weight:635.22KDX1381
CAS:KDX1381 is a bivalent CK2α inhibitor with an IC50 of 17 nM and a KD of 54 nM. It demonstrates antitumor activity in murine 786-O and A375 xenograft models. Furthermore, when combined with a vascular endothelial growth factor receptor (VEGFR) inhibitor or DNA-damaging agents, KDX1381 enhances antitumor effects in mouse hepatocellular carcinoma and glioma models.Formula:C32H32F2N6O4SColor and Shape:SolidMolecular weight:634.70LXRβ agonist-2
CAS:LXRβ agonist-2 is a highly potent and β-selective liver X receptor (LXRβ) agonist with EC50 of 7 nM.Formula:C32H31F6N3O7Purity:98%Color and Shape:SolidMolecular weight:683.595-Carboxy-2′-deoxycytidine
CAS:5-Carboxy-2′-deoxycytidine is a metabolite of Trifluridine.Formula:C10H13N3O6Color and Shape:SolidMolecular weight:271.227CIT-ALD
CAS:CIT-ALD is an aldehyde intermediate formed during the metabolism of Citalopram. It has potential applications in the research of neurological disorders.Formula:C18H14FNO2Molecular weight:295.31Buspirone N-oxide
CAS:Buspirone N-oxide (Bu N-oxide) is a metabolite of Buspirone. Buspirone is an orally active 5-HT1A receptor agonist and a dopamine D2 (dopamine D2) autoreceptor antagonist. It is an anxiolytic agent used for research in generalized anxiety disorder.Formula:C21H31N5O3Color and Shape:SolidMolecular weight:401.503Z21090
CAS:Z21090 (ZL40) is a highly effective inhibitor of PDE 4, exhibiting an IC 50 value of 37.4 nM, and possesses oral bioavailability. It is significant in the study of alcohol-related diseases [1].Formula:C12H14ClN3O3Color and Shape:SolidMolecular weight:283.71Antidiabetic agent 5
CAS:Compound S1 (antidiabetic agent 5) is an antidiabetic agent that effectively inhibits the enzymes α-glucosidase and α-amylase, demonstrating IC50 values of 3.91 µM and 8.89 µM, respectively. It reduces sugar levels and holds potential for type-II diabetes research [1].Formula:C17H15N3O4SColor and Shape:SolidMolecular weight:357.38(6S)-CP-470711
CAS:(6S)-CP-470711 (Compound 8) acts as an inhibitor of sorbitol dehydrogenase (SDH) in both humans and rats, exhibiting inhibitory concentrations (IC50) of 19 nM and 27 nM, respectively. Additionally, (6S)-CP-470711 has been shown to ameliorate diabetes in rats induced by Streptozotocin.Formula:C18H26N6O2Color and Shape:SolidMolecular weight:358.44DRX-065
CAS:DRX-065, a deuterated R-enantiomer of pioglitazone, treats NASH without PPARγ weight gain issues.Formula:C19H20N2O3SColor and Shape:SolidMolecular weight:357.45DEL-I25
CAS:DEL-I25 is an effective activator of GPX4 that protects cells from ferroptosis (iron-dependent cell death).Formula:C21H23N5O3Color and Shape:SolidMolecular weight:393.44Lipid 11
CAS:Lipid 11 (Compound Lipid 1) is a cationic lipid designed for nucleic acid delivery. It forms lipid nanoparticles (LNPs) through electrostatic interactions with nucleic acids, such as ceDNA. By using its cationic amine groups, Lipid 11 complexes with negatively charged nucleic acids, enabling cellular uptake and release of the nucleic acid cargo. Lipid 11 shows potential for use in the development of gene therapy drug delivery systems.Formula:C43H85NO4Color and Shape:SolidMolecular weight:680.14N-Boc-3-hydroxy-1,2,3,6-tetrahydropyridine
CAS:N-Boc-3-hydroxy-1,2,3,6-tetrahydropyridine enhances β-glucocerebrosidase (β-Glucocerebrosidase) activity by 20%. It is used in research on lysosomal storage disorders and other protein accumulation diseases.Formula:C10H17NO3Color and Shape:SolidMolecular weight:199.25Bestatin methyl ester
CAS:Bestatin methyl ester (600, 900 µM; 24 h) inhibits spore cell differentiation in Dictyostelium discoideum.Formula:C17H26N2O4Color and Shape:SolidMolecular weight:322.4CGS 24592
CAS:CGS-24592 is an orally active, selective, and potent inhibitor of neutral endopeptidase 24.11 (NEP), with an IC50 value of 1.6 nmol/L. It reduces the degradation of atrial natriuretic peptide (ANP), thereby increasing plasma ANP concentration and lowering blood pressure. CGS-24592 shows potential for research in cardiovascular diseases such as hypertension and congestive heart failure.Formula:C19H23N2O6PColor and Shape:SolidMolecular weight:406.37LTA4H-IN-2
CAS:LTA4H-IN-2 (compound (S)-2) acts as an orally active inhibitor targeting Leukotriene A4 Hydrolase, exhibiting potent activity with an IC 50 of less than 3 nM [1].Formula:C20H19FN6O2Color and Shape:SolidMolecular weight:394.4(Rac)-8-Hydroxy-efavirenz
CAS:(Rac)-8-Hydroxy-efavirenz is a metabolite of Efavirenz, a non-nucleoside reverse transcriptase inhibitor (NNRTI) used in the treatment of HIV-1.Formula:C14H9ClF3NO3Color and Shape:SolidMolecular weight:331.6744-Acetylphenylboronic acid
CAS:4-Acetylphenylboronic acid acts as an effective inhibitor targeting carbonic anhydrase II (CAII), displaying inhibitory concentrations (IC50) of 246 μM for bovine CAII (bCA II) and 281.40 μM for human CAII (hCA II).Formula:C8H9BO3Color and Shape:SolidMolecular weight:163.97Dioctanoylphosphatidic acid sodium
CAS:Dioctanoylphosphatidic acid sodium serves as a modulator of phagocyte respiratory bursts, a precursor to diacylglycerol and lyso-phosphatidic acid, and influences the phosphorylation of the mammalian target of rapamycin (mTOR). Additionally, it enhances the viability of gallbladder cancer cells inhibited by histone deacetylase inhibitors (HDACI). This compound is derived from glycerophospholipids through the action of phospholipase D.Formula:C19H36NaO8PColor and Shape:SolidMolecular weight:446.45
