Metabolism
Metabolism inhibitors are compounds that interfere with metabolic pathways, altering the production and utilization of energy within cells. These inhibitors are used to study the regulation of metabolism, the role of metabolic pathways in diseases like cancer and diabetes, and to develop new therapeutic strategies. Metabolism inhibitors can target various enzymes and processes involved in glycolysis, fatty acid oxidation, and other metabolic functions. At CymitQuimica, we offer a wide range of high-quality metabolism inhibitors to support your research in biochemistry, metabolic disorders, and drug development.
Subcategories of "Metabolism"
- AhR(42 products)
- Aminopeptidase(76 products)
- CETP(20 products)
- Carbonic Anhydrase(196 products)
- Casein Kinase(138 products)
- DHFR(32 products)
- Decarboxylase(4 products)
- Dehydrogenase(302 products)
- FAAH(64 products)
- FXR(62 products)
- Factor Xa(85 products)
- Fatty Acid Synthase(37 products)
- Ferroptosis(226 products)
- GR(3 products)
- GSNOR(3 products)
- Glucokinase(57 products)
- HIF/HIF Prolyl-Hydroxylase(146 products)
- HMG-CoA Reductase(34 products)
- Hydroxylase(36 products)
- IDO(84 products)
- LDL(7 products)
- Lipase(107 products)
- Lipid(61 products)
- Lipoxygenase(134 products)
- MAO(87 products)
- MPO(2 products)
- NAMPT(40 products)
- P450(6 products)
- PAI-1(26 products)
- PDE(169 products)
- PED(1 products)
- PKM(17 products)
- PPAR(170 products)
- Phospholipase(86 products)
- ROR(47 products)
- Retinoid Receptor(22 products)
- SGK(10 products)
- Thioredoxin(12 products)
- Transferase(29 products)
- Transporter(45 products)
- UGT(4 products)
- Xanthine Oxidase (XO) Inhibitors(9 products)
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Found 9188 products of "Metabolism"
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Clopidogrel-β-D-glucuronide
CAS:Clopidogrel-β-D-glucuronide is a metabolite of Clopidogrel. It directly interacts with the CYP2C8 enzyme and strongly inhibits the hepatic enzyme CYP2C8.Formula:C21H22ClNO8SColor and Shape:SolidMolecular weight:483.919Desmonomethylpromazine
CAS:Desmonomethylpromazine is a demethylated metabolite of Promazine that can penetrate the brain. It enters red blood cells and tissues via passive diffusion and is distributed in organs such as the lungs, liver, and kidneys in rats.Formula:C16H18N2SColor and Shape:SolidMolecular weight:270.39SelB-1
CAS:SelB-1 acts as a dual inhibitor of Topoisomerase I/II (TopoisomeraseI/II), exhibiting anticancer activity suitable for research on prostate and colon cancers. Additionally, SelB-1 can induce the expression of autophagy (autophagy) genes and lipid peroxidation while reducing GSH levels.Formula:C32H24O5Color and Shape:SolidMolecular weight:488.53Pyripyropene A
CAS:Pyripyropene A is a potent and selective inhibitor of sterol O-acyltransferase 2 (SOAT2)/acyl-coenzyme A:cholesterol acyltransferase 2 (ACAT2)(IC50 of 0.07 μM).Formula:C31H37NO10Purity:98%Color and Shape:SolidMolecular weight:583.63Raloxifene N-Oxide
CAS:Raloxifene N-Oxide is a Raloxifene oxidative degradation product.Formula:C28H27NO5SPurity:98%Color and Shape:SolidMolecular weight:489.58Miaosporone A
Miaosporone A: angucyclic quinone, cytotoxic to MCF-7, NCI-H187, Vero cells; anti-TB and anti-malaria with IC50 of 2.4 μM, 2.5 μM.Formula:C19H18O5Color and Shape:SolidMolecular weight:326.34RORγt/DHODH-IN-3
RORγt/DHODH-IN-3 (compound (S)-14d) is a potent, orally active dual inhibitor of RORγt (IC50: 0.098 μM) and DHODH (IC50: 0.432 μM).RORγt/DHODH-IN-1 hasFormula:C24H26ClF6N3O3SColor and Shape:SolidMolecular weight:585.99L-690330 hydrate
L-690330 hydrate inhibits IMPase; Ki: 0.30 μM (human), 0.42 μM (bovine cortex); 0.27 μM (recom. human), 0.19 μM (bovine).Formula:C8H14O9P2Color and Shape:SolidMolecular weight:316.14PKM2-IN-9
CAS:PKM2-IN-9 (compound C1) is a potent inhibitor of PKM2, demonstrating a 75% inhibition rate at 50 μM. It plays a significant role in cancer research.Formula:C24H22N4O2Color and Shape:SolidMolecular weight:398.457Darlifarnib
CAS:Darlifarnib (Compound (S)-058) is an inhibitor of farnesyl transferase and geranylgeranyltransferase, with IC50 values of ≤ 10 nM and > 1000 nM, respectively. It exhibits high metabolic stability in human and mouse liver microsomes, with a half-life of over 100 minutes.Formula:C29H20N6OColor and Shape:SolidMolecular weight:468.509PDHK-IN-5
PDHK-IN-5, potent PDHK2 (0.006 μM IC50) & PDHK4 (0.0329 μM IC50) inhibitor, may be explored for cancer and diabetes treatment.Formula:C30H31N5O2Color and Shape:SolidMolecular weight:493.6Lipoxin A5
CAS:LXA5 is made from EPA by leukocytes, contracts guinea pig lungs like LXA4/LXB4, but doesn't dilate aorta.Formula:C20H30O5Color and Shape:SolidMolecular weight:350.45Myxothiazol
CAS:Myxothiazol blocks mitochondrial complex III and triggers SESN2, a gene important for stress response.Formula:C25H33N3O3S2Color and Shape:SolidMolecular weight:487.68α-Amylase-IN-7
CAS:α-Amylase-IN-7 (Compound 6e) is an inhibitor of α-Amylase, with an IC50 of 40 μM, indicating its potency. This compound shows potential as an anti-diabetic medication.Formula:C18H15ClN6O2SMolecular weight:414.87PDE4-IN-14
CAS:PDE4-IN-14 (Compound 1) serves as an inhibitor of phosphodiesterase 4 (PDE4), applicable in research concerning diseases associated with PDE4, includingFormula:C19H20F2N4O3SColor and Shape:SolidMolecular weight:422.45Carbonic anhydrase inhibitor 4
CA inhibitor 4, photoprobe; targets hCA I-XIV; Ki: 640-1166 nM.Formula:C21H18N2O4SColor and Shape:SolidMolecular weight:394.44AD015
CAS:AD015 is a dual inhibitor of angiotensin-converting enzyme (ACE) and neprilysin (NEP), effectively inhibiting NEP, nACE, and cACE with IC50 values of 0.009, 0.019, and 0.0008 μM, respectively.Formula:C23H26N2O4SColor and Shape:SolidMolecular weight:426.53L 671776
CAS:L 671776 is an inositol monophosphatase inhibitor.Formula:C23H32O5Purity:98%Color and Shape:SolidMolecular weight:388.5AD011
AD011, a cACE/NEP inhibitor derived from lenopril-tryptophan, may offer strong anti-hypertensive, cardioprotective benefits.Formula:C27H33N3O5Color and Shape:SolidMolecular weight:479.57CYP2C1/CYP2C19-IN-2
CYP2C1/CYP2C19-IN-2 is a potent inhibitor of CYP2C9/CYP2C19 without liver toxicity or genotoxicity and can be used to study Zika virus (ZIKV) infection.Formula:C27H28N2O6SColor and Shape:SolidMolecular weight:508.59
