GPCR/G-Protein
GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.
Subcategories of "GPCR/G-Protein"
- 5-HT Receptor(942 products)
- Adenosine Receptor(242 products)
- Adrenergic Receptor(2,949 products)
- Bombesin Receptor(30 products)
- Bradykinin Receptor(59 products)
- CXCR(149 products)
- CaSR(32 products)
- Cannabinoid Receptor(195 products)
- Dopamine Receptor(410 products)
- Endothelin Receptor(75 products)
- GNRH Receptor(73 products)
- GPCR19(31 products)
- GRK(32 products)
- GTPase(21 products)
- Glucagon Receptor(166 products)
- Hedgehog/Smoothened(45 products)
- Histamine Receptor(359 products)
- LPA Receptor(21 products)
- Melatonin Receptor(24 products)
- OX Receptor(40 products)
- Opioid Receptor(298 products)
- PAFR(11 products)
- PKA(49 products)
- S1P Receptor(17 products)
- SGLT(30 products)
- Sigma receptor(46 products)
Show 18 more subcategories
Found 5378 products of "GPCR/G-Protein"
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Dipivefrin hydrochloride
CAS:<p>Dipivefrin hydrochloride (Dipivefrin HCl) that is available as an ophthalmic solution is a prodrug of adrenaline, which is used to treat glaucoma.</p>Formula:C19H27NO5·HClPurity:99.22% - 99.92%Color and Shape:Less Gas With A Sweet Odor Colorless Gas With A Sweet OdorMolecular weight:387.9Fenclozine Maleate
CAS:<p>Fenclozine Maleate (S 1429) is a potential histamine H1 receptor antagonist , which can be used to study fever, inflammation and pain.</p>Formula:C45H47ClN2O12Purity:98.47%Color and Shape:SoildMolecular weight:843.314Ebalzotan
CAS:<p>NAE-086 is a high-affinity and selective 5-HT(1A) receptor ligand with a K(i) value of 4.5 nM in membranes from rat hippocampus.</p>Formula:C19H30N2O2Purity:98.09% - 99.41%Color and Shape:SolidMolecular weight:318.45DREADD agonist 21
CAS:<p>DREADD agonist 21 is a potent agonist of human muscarinic acetylcholine M3 receptors (EC50=1.7 nM).</p>Formula:C17H18N4Purity:99.94%Color and Shape:SolidMolecular weight:278.35HJC0197
CAS:<p>HJC0197 is a selective Epac antagonist; blocks cAMP-induced activation with IC50=5.9 μM for Epac2.</p>Formula:C19H21N3OSPurity:98.05%Color and Shape:SolidMolecular weight:339.45PF-06882961
CAS:PF-06882961 is an orally bioavailable glucagon-like peptide-1 receptor (GLP-1R) agonist.Formula:C31H30FN5O4Purity:97.19% - 99.56%Color and Shape:SolidMolecular weight:555.6Erenumab
CAS:<p>Erenumab: human antibody blocking CGRP receptors to prevent migraines.</p>Purity:99.43% (SEC-HPLC) - > 95%Color and Shape:LiquidMolecular weight:146.2 kDaTropanserin
CAS:<p>Tropanserin (MDL 72422) is a 5-hydroxytryptamine receptor antagonist with anxiolytic activity that is used to treat depression and cognitive impairment.</p>Formula:C17H23NO2Purity:99.74%Color and Shape:SolidMolecular weight:273.37PF-04995274
CAS:<p>PF-04995274: potent, selective partial 5-HT4R agonist; EC50 0.26-0.47 nM; brain penetrant; may treat Alzheimer's cognitive issues.</p>Formula:C23H32N2O6Purity:99.52%Color and Shape:SolidMolecular weight:432.51Vilazodone
CAS:<p>Vilazodone (SB659746A): an SSRI and 5-HT-1A agonist, boosts serotonin to treat depression and anxiety.</p>Formula:C26H27N5O2Purity:99.61%Color and Shape:Light Yellow SolidMolecular weight:441.52Ziprasidone
CAS:<p>Ziprasidone (Geodon) is a united 5-HT (serotonin) and dopamine receptor antagonist which shows potent effects of antipsychotic activity.</p>Formula:C21H21ClN4OSPurity:99.55%Color and Shape:Tan SolidMolecular weight:412.94Metaraminol tartrate
CAS:<p>Metaraminol tartrate (Metaradrine tartrate) is a sympathomimetic agent that acts predominantly at alpha-1 adrenergic receptors.</p>Formula:C13H19NO8Purity:99.68%Color and Shape:White PowderMolecular weight:317.292',5'-Dideoxyadenosine
CAS:<p>2',5'-Dideoxyadenosine is a potent and non-competitive adenylyl cyclase inhibitor via binding the P-site (IC50: 3 μM).</p>Formula:C10H13N5O2Purity:99.55%Color and Shape:White SolidMolecular weight:235.24Mebhydrolin napadisylate
CAS:<p>Mebhydrolin napadisylate (Incidal) is an antihistamine used to relieve allergic symptoms caused by histamine release, including nasal allergies and allergic</p>Formula:C19H20N2C10H8O6S2Purity:99.35% - 99.96%Color and Shape:White Or Almost White CrystallineMolecular weight:420.52Glycerol phenylbutyrate
CAS:Glycerol phenylbutyrate (HPN-100) (GPB) is a new generation ammonia scavenger drug and it also is a sigma-2 (σ2) receptor ligand (pKi: 8.02).Formula:C33H38O6Purity:98.54% - 99.74%Color and Shape:SolidMolecular weight:530.65Monatepil 2maleate
Monatepil 2maleate is an orally active Ca2+-channel antagonist and ACAT inhibitor with alpha(1)-adrenergic receptor blocking activity and antiarrhythmic properties that inhibit vasoconstriction.Monatepil 2maleate may be used to study atherosclerosis.Formula:C32H34FN3O5SPurity:98%Color and Shape:SolidMolecular weight:591.69Pheniramine maleate
CAS:Pheniramine maleate (Trimetose), an alkylamine derivative with antihistaminic and vasodilatory properties, binds to histamine H1 receptors.Formula:C16H20N2·C4H4O4Purity:99.85%Color and Shape:Physical Description White Powder With A Faint Amine-Like Odor Melting Point 107°CMolecular weight:356.42Sarizotan 2HCl
CAS:<p>Sarizotan 2HCl is an hERG channel inhibitor and 5-hydroxytryptamine 5-HT1A receptor agonist with potential antidepressant effects for the study of Parkinsonian movement disorders.</p>Formula:C22H23Cl2FN2OPurity:98.83%Color and Shape:SoildMolecular weight:421.34Hydroxyzine Pamoate
CAS:<p>Hydroxyzine Pamoate (Bobsule) is a histamine H1 receptor antagonist that is effective in the treatment of chronic urticaria and histamine-mediated pruritus.</p>Formula:C44H43ClN2O8Purity:99.49%Color and Shape:SolidMolecular weight:763.27Amylin, amide, human
CAS:Amylin, amide, human(DAP Amide) is a 37-amino acid peptide hormone co-secreted with insulin to regulate postprandial glucose levels.Formula:C165H261N51O55S2Purity:98%Color and Shape:SolidMolecular weight:3903.28ONC206
CAS:<p>ONC206, an analogue of the TRAIL inducer ONC201, acts as a selective antagonist of the D2-like dopamine receptors (DRD2/3/4) at nanomolar concentrations and</p>Formula:C23H22F2N4OPurity:99.38% - 99.81%Color and Shape:SolidMolecular weight:408.44Amitriptyline hydrochloride
CAS:<p>Amitriptyline hydrochloride (Annoyltin) is the hydrochloride salt of the tricyclic dibenzocycloheptadiene amitriptyline with antidepressant and antinociceptive</p>Formula:C20H24ClNPurity:97% - 99.94%Color and Shape:Crystals White To Off-White PowderMolecular weight:313.86Bromperidol
CAS:<p>Bromperidol (R-11333) is a butyrophenone derivative and it is a potent and long-acting neuroleptic.</p>Formula:C21H23BrFNO2Purity:99.89%Color and Shape:Tan SolidMolecular weight:420.32Tirzepatide monosodium salt
Tirzepatide sodium salt (LY3298176 sodium salt) is a GIP and GLP-1 receptor agonist with neuroprotective activity and can be used to treat obesity.Formula:C225H347N48O68NaPurity:99.69%Color and Shape:SoildMolecular weight:4835.51Lofepramine
CAS:<p>Lofepramine (Leo 640) is a potent tricyclic antidepressant that is extensively metabolized to desipramine.</p>Formula:C26H27ClN2OPurity:98.38%Color and Shape:Crystals From Methanol Or Acetone SolidMolecular weight:418.96Ifenprodil
CAS:<p>Ifenprodil (RC61-91) inhibits NMDA receptor subunits GluN1 & GluN2B, GIRK channels, and affects alpha1, serotonin, sigma receptors.</p>Formula:C21H27NO2Purity:99.58%Color and Shape:White Crystalline PowderMolecular weight:325.44Carbinoxamine Maleate Salt
CAS:<p>Carbinoxamine Maleate Salt (Lergefin) is an ethanolamine class of H1 antihistamines with mild antimuscarinic and sedative properties.</p>Formula:C20H23ClN2O5Purity:99.97%Color and Shape:Off-White SolidMolecular weight:406.86Isoprenaline hydrochloride
CAS:Isoprenaline hydrochloride (NCI-c55630) is a potent beta-adrenergic agonist with the peripheral vasodilator, bronchodilator, and cardiac stimulating properties.Formula:C11H18ClNO3Purity:98% - 99.65%Color and Shape:Turn Brownish-Pink Upon Prolonged Exposure To Air (Ntp 1992)Molecular weight:247.719Ketotifen fumarate
CAS:<p>Ketotifen fumarate (HC 20511 fumarate) is a cycloheptathiophene blocker of histamine H1 receptors and release of inflammatory mediators.</p>Formula:C23H23NO5SPurity:99.25% - 99.73%Color and Shape:SolidMolecular weight:425.50Azacyclonol
CAS:<p>Azacyclonol (MER 17) is a drug used to diminish hallucinations in psychotic individuals.</p>Formula:C18H21NOPurity:99.46%Color and Shape:Solid PowderMolecular weight:267.37Eletriptan hydrobromide
CAS:<p>Eletriptan hydrobromide (Eletriptan HBr) is an orally active agonist with specific affinity for the 5-hydroxytriptamine1B/1D receptor.</p>Formula:C22H27BrN2O2SPurity:99.69% - 99.85%Color and Shape:Tan SolidMolecular weight:463.43Gevotroline
CAS:<p>Gevotroline, a chemical in palm wine that can be used to treat psychosis, is a 5-HT2 receptor antagonist that can be used to study behavioral disorders.</p>Formula:C19H20FN3Purity:98.65%Color and Shape:SolidMolecular weight:309.38Brefonalol HCl
<p>Brefonalol HCl, ADRA blocker for neurological/cardiovascular issues, treats angina, arrhythmias, hypertension.</p>Formula:C22H29ClN2O2Purity:99.45%Color and Shape:SolidMolecular weight:388.93Blonanserin
CAS:Blonanserin (AD-5423), approved in Japan (2008), is an atypical antipsychotic with fewer side effects like EPS, sedation, or hypotension.Formula:C23H30FN3Purity:99.85%Color and Shape:SolidMolecular weight:367.5Maprotiline hydrochloride
CAS:<p>Maprotiline hydrochloride (Psymion) is a tetracyclic antidepressant akin to tricyclics with similar side effects.</p>Formula:C20H24ClNPurity:99.68% - 99.84%Color and Shape:White PowderMolecular weight:313.864CD80-IN-3
CAS:<p>CD80-IN-3 is a potent CD80 inhibitor and inhibits CD80/CD28 interaction (Kd: 125 nM; EC50: 630 nM).</p>Formula:C17H10FN3O3Purity:98.08%Color and Shape:SolidMolecular weight:323.28Capeserod
CAS:<p>Capeserod is a potential 5-HT4 receptor (5-hydroxytryptamine receptor 4) agonist for the study of digestive disorders and neurological disorders.</p>Formula:C23H25ClN4O4Purity:98.10% - 99.94%Color and Shape:SolidMolecular weight:456.92PACAP-38 (31-38), human, mouse, rat acetate
<p>PACAP-38 (31-38) acetate stimulates PAC1 receptor and boosts NPY and catecholamine in sympathetic neurons.</p>Formula:C49H87N17O13Purity:99.92%Color and Shape:SolidMolecular weight:1122.3212(S)-HpEPE
CAS:<p>12(S)-HpEPE, a fatty acid created by 12-lipoxygenase on EPA, has unclear biological activities but may resemble 12(S)-HpETE.</p>Formula:C20H30O4Color and Shape:SolidMolecular weight:334.456Stressin I TFA
<p>Stressin I (Cyclo(31-34)[DPhe12, Nle21, 38, Glu31, Lys34]Ac-hCRF(4-41)) TFA, with a K i of 1.7 nM, is a potent and selective agonist of the CRF1 receptor.</p>Purity:98%Color and Shape:Odour SolidGuanylin (mouse, rat)
CAS:<p>Guanylin (mouse, rat), a peptide consisting of 15 amino acids, acts as an activator of intestinal guanylate cyclase and is utilized in diarrhea research [1].</p>Formula:C60H90N16O22S4Purity:98%Color and Shape:SolidMolecular weight:1515.71A3AR agonist 2
<p>Compound 19, a selective A3 Adenosine Receptor (A3AR) agonist (K i : 22.1 nM), effectively stimulates β-arrestin2 recruitment with an EC 50 value of 4.36 nM.</p>Formula:C34H34N6O6Purity:98%Color and Shape:SolidMolecular weight:622.67GR 82334
CAS:<p>Tachykinin NK1 receptor antagonist.</p>Formula:C69H91N15O16Purity:98%Color and Shape:SolidMolecular weight:1386.57(+)-5-trans Cloprostenol
CAS:<p>Cloprostenol, a synthetic PGF2α derivative, induces estrus and treats reproductive issues in livestock; its minor impurity, (+)-5-trans, is less effective.</p>Formula:C22H29ClO6Color and Shape:SolidMolecular weight:424.925-HT6R antagonist 1
<p>Compound 8 (5-HT6R antagonist 1), a 5-HT6R antagonist (K i : 5 nM), not only demonstrates inhibition of platelet aggregation and excellent metabolic stability</p>Formula:C17H22F2N6OPurity:98%Color and Shape:SolidMolecular weight:364.39CB2 PET Radioligand 1
<p>CB2 PET Radioligand 1 (compound [18F]9) is a positron emission tomography (PET) radioligand with high affinity for the human cannabinoid receptor 2 (hCB2, Ki=7.</p>Formula:C20H19F3N4OPurity:98%Color and Shape:SolidMolecular weight:388.394-Thiouridine 5′-triphosphate disodium
CAS:<p>4-Thiouridine 5′-triphosphate (4-Thio-UTP) tetrasodium functions as a potent agonist at P2Y 2 and P2Y 4 receptors, with half-maximal effective concentrations (</p>Formula:C9H11N2Na2O14P3SPurity:98%Color and Shape:SolidMolecular weight:546.19TCMCB07 TFA
<p>TCMCB07 TFA is a cyclic nonapeptide and an orally active, brain-penetrating antagonist of the melanocortin receptor 4 (MC4R), playing a significant role in</p>Formula:C63H87N15O11·xC2HF3O2Purity:98%Color and Shape:SolidMolecular weight:1230.46 (free base)Azaline
CAS:<p>Azaline is a gonadorelin antagonist.</p>Formula:C74H106ClN23O12Purity:98%Color and Shape:SolidMolecular weight:1545.26BQ-3020 ammonium
<p>BQ-3020 ammonium, a selective endothelin receptor (ET B receptor) agonist, demonstrates inhibition of [125 I] ET-1 binding to ET B receptors with an IC50 of 0.2</p>Formula:C96H140N20O25S·xNH3Purity:98%Color and Shape:SolidMolecular weight:2006.32 (free base)
