GPCR/G-Protein
GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.
Subcategories of "GPCR/G-Protein"
- 5-HT Receptor(1,025 products)
- Adenosine Receptor(249 products)
- Adrenergic Receptor(3,024 products)
- Bombesin Receptor(35 products)
- Bradykinin Receptor(61 products)
- CXCR(158 products)
- CaSR(34 products)
- Cannabinoid Receptor(217 products)
- Cholecystokinin(1 products)
- Dopamine Receptor(445 products)
- Endothelin Receptor(86 products)
- GNRH Receptor(84 products)
- GPCR19(33 products)
- GRK(33 products)
- GTPase(23 products)
- Glucagon Receptor(194 products)
- Hedgehog/Smoothened(49 products)
- Histamine Receptor(385 products)
- LPA Receptor(21 products)
- Melatonin Receptor(26 products)
- OX Receptor(41 products)
- Opioid Receptor(327 products)
- PAFR(14 products)
- PKA(60 products)
- S1P Receptor(18 products)
- SGLT(31 products)
- Sigma receptor(46 products)
Show 19 more subcategories
Found 5990 products of "GPCR/G-Protein"
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PAMP-12(human, porcine)
CAS:Potent endogenous peptide agonist of Mas related GPR X2 (MRGPRX2, EC50 = 57.2 nM). Corresponds to amino acids 9 to 20 of proadrenomedullin.Formula:C77H119N25O14Purity:98%Color and Shape:SolidMolecular weight:1618.95TCMCB07
CAS:TCMCB07, a cyclic nonapeptide, serves as an orally active, brain-penetrant antagonist of the melanocortin receptor 4 (MC4R), with significant implications inFormula:C63H87N15O11Purity:98%Color and Shape:SolidMolecular weight:1230.46PD 144418 oxalate
CAS:PD 144418 oxalate: σ1 receptor ligand, Ki=0.08 nM; 1377 nM for σ2, minimal affinity elsewhere; potential antipsychotic.Formula:C20H24N2O5Purity:98.76%Color and Shape:SolidMolecular weight:372.42BA 1
CAS:Potent BB1, BB2, and BB3 agonist; IC50: 0.26, 1.55, 2.52 nM. Boosts glucose transport in myocytes, promotes cancer cell growth in vitro.Formula:C57H76N14O11Purity:98%Color and Shape:SolidMolecular weight:1133.32Oxmetidine FA
Oxmetidine FA is an orally available specific histamine H2 receptor antagonist with antiulcerogenic properties.Formula:C20H23N5O5SPurity:97.34%Color and Shape:SoildMolecular weight:445.49Avorelin
CAS:Avorelin, a luteinizing hormone releasing hormone (LH-RH) agonist, is used potentially for the treatment of prostate.Formula:C65H85N17O12Purity:98%Color and Shape:SolidMolecular weight:1296.48CACPD2011a-0001278239
CAS:CACPD2011a-0001278239 is a β2AR hybrid agonist with high affinity binding to both the wild-type and T164I β2AR variants. It exhibits neither cytotoxicity nor mutagenicity, making it suitable for asthma research.Formula:C21H22N4O4Color and Shape:SolidMolecular weight:394.42ATMW-2
ATMW-2 is an antagonist engineered using NeuralGenThesis (NGT) technology, specifically targeting the melanocortin 2 receptor (MC2R).Formula:C27H29ClN2O4Color and Shape:SolidMolecular weight:480.98BMS-604992 free base
CAS:BMS-604992 (EX-1314), a selective GHSR agonist, binds strongly (ki=2.3 nM), is orally active, and increases rodent food intake.Formula:C24H31N7O5Color and Shape:SolidMolecular weight:497.556Sulfatroxazole
CAS:Sulfatroxazole (Isosulfafurazole) (compound 12) is a selective antagonist of the ETA receptor with an IC50 of 0.26 μM.Formula:C11H13N3O3SColor and Shape:SolidMolecular weight:267.3FFN246
CAS:FFN246, a fluorescent probe, concurrently targets the serotonin transporter (SERT) and vesicular monoamine transporter 2 (VMAT2), exhibiting excitation andFormula:C15H13FN2OPurity:98%Color and Shape:SolidMolecular weight:256.27PAR650097
PAR650097 is a humanized monoclonal antibody targeting PAR2, used in migraine research.Purity:96.67% (SEC-HPLC) - 98.83% (SEC-HPLC)Color and Shape:LiquidMolecular weight:144.1 kDaδ8-THC acetate
CAS:Delta8-THC acetate (Delta8-tetrahydrocannabinol) is a psychoactive cannabinoid that binds to the cannabinoid receptor 1 (CB1 receptor) and exhibits anti-nausea, appetite-stimulating, and anti-inflammatory effects. It may also offer neuroprotective benefits and has potential applications in research on anxiety and depression.Formula:C23H32O3Color and Shape:SolidMolecular weight:356.5SBI-810
CAS:SBI-810 is a functional selective β-arrestin-biased allosteric modulator of the neurotensin receptor 1 (NTSR1). In the presence of the endogenous ligand neurotensin (NT), SBI-810 regulates NTSR1 signaling through a G protein-specific mechanism. It fully antagonizes NT-induced Gq activation and partially antagonizes NT-induced Gi1 activation, allowing NTSR1 to activate GoA and G12.Formula:C27H34N4O2Color and Shape:SolidMolecular weight:446.59Esmolol acid hydrochloride
CAS:Esmolol acid (ASL-8123) hydrochloride is a mild antagonist of β-adrenergic receptors. It inhibits the heart rate and diastolic pressure responses induced by Isoproterenol in a dose-dependent manner and is applicable for renal failure research.Formula:C15H24ClNO4Color and Shape:SolidMolecular weight:317.81Cannabidivarinic acid
CAS:Cannabidivarinic acid (CBDVA), the carboxylic acid precursor to cannabidivarin (CBDV), is a non-psychoactive cannabinoid found in Cannabis and known for its anti-inflammatory properties.Formula:C20H26O4Color and Shape:SolidMolecular weight:330.42PSB-SB-1203
CAS:PSB-SB-1203 (Compound 25b) is a dual CB1/CB2 ligand that blocks the CB1 receptor and activates the CB2 receptor with a CB1 Ki of 0.244 μM, a CB2 Ki of 0.210 μM, and an EC50 of 0.054 μM. It shows potential for research in obesity and cancer.Formula:C25H30O4Color and Shape:SolidMolecular weight:394.5MDL 29913
CAS:NK2 tachykinin receptor selective antagonist.Formula:C40H56N8O6Purity:98%Color and Shape:SolidMolecular weight:745ANXA3 degrader 1
ANXA3 degrader 1 (Compound 18a5) is a highly selective ANXA3 degrader with activity against cancer cells. It demonstrates significant inhibitory effects in a triple-negative breast cancer (TNBC) tumor xenograft model, with a tumor growth inhibition (TGI) rate of 96%.Formula:C30H32N6O2S2Color and Shape:SolidMolecular weight:572.74CYN 154806
CAS:CYN 154806: potent sst2 antagonist; pIC50: 8.58 (sst2), 5.41 (sst1), 6.07 (sst3), 5.76 (sst4), 6.48 (sst5).Formula:C56H68N12O14S2Purity:98%Color and Shape:SolidMolecular weight:1197.34
