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Metabolism

Metabolism

Metabolism inhibitors are compounds that interfere with metabolic pathways, altering the production and utilization of energy within cells. These inhibitors are used to study the regulation of metabolism, the role of metabolic pathways in diseases like cancer and diabetes, and to develop new therapeutic strategies. Metabolism inhibitors can target various enzymes and processes involved in glycolysis, fatty acid oxidation, and other metabolic functions. At CymitQuimica, we offer a wide range of high-quality metabolism inhibitors to support your research in biochemistry, metabolic disorders, and drug development.

Subcategories of "Metabolism"

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Found 9197 products of "Metabolism"

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  • F1874-108

    CAS:
    F1874-108 functions as an inhibitor of both brassinosteroid biosynthesis and signal transduction [1].
    Formula:C15H14N4O2S
    Color and Shape:Solid
    Molecular weight:314.36

    Ref: TM-T82422

    5mg
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    50mg
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  • Casein kinase 1δ-IN-4

    CAS:
    "Casein kinase 1δ-IN-4 (compound 567) is a potent inhibitor of casein kinase 1δ with potential application in Alzheimer's disease research [1]."
    Formula:C16H12N6S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:320.37

    Ref: TM-T79127

    5mg
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    50mg
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  • 5α-Androstan-3β-ol

    CAS:
    5α-Androstan-3β-ol, a steroidal androgen, demonstrates selective interaction with cellular components, showing affinity for the androgen receptor (AR) with an IC50 of 1.7 µM and activating the pregnane X receptor (PXR) in HepG2 cells with an EC50 of 0.8 µM. It selectively inhibits the hydroxylase activities of 16α- and 6β-hydroxylase over 16β- or 7α-hydroxylase, with IC50 values of 70 and 110 µM, compared to >150 µM for the latter enzymes, indicating a specificity in its enzyme inhibition profile. Additionally, administration of this compound at a dosage of 30 mg/kg results in a decrease in testis weight and sperm production in mice, highlighting its biological effects on male reproductive parameters.
    Formula:C19H32O
    Color and Shape:Solid
    Molecular weight:276.46

    Ref: TM-T84963

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  • ICMT-IN-38

    CAS:
    ICMT-IN-38 (Compound 42) is an ICMT inhibitor, demonstrating an IC50 value of 0.049 μM [1].
    Formula:C22H28ClNO
    Color and Shape:Solid
    Molecular weight:357.92

    Ref: TM-T82105

    5mg
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  • GSK2256294A

    CAS:

    GSK2256294A (GSK 2256294) is potent, selective inhibitor of recombinant human, rat and mouse sEH with IC50 of 27 pM, 61 pM and 189 pM, respectively.

    Formula:C21H24F3N7O
    Purity:99.86% - 99.86%
    Color and Shape:Solid
    Molecular weight:447.46

    Ref: TM-T15430

    1mg
    96.00€
    2mg
    134.00€
    5mg
    207.00€
    10mg
    329.00€
    25mg
    499.00€
    50mg
    660.00€
    100mg
    873.00€
  • TP-1454

    CAS:
    TP-1454 is an activator against PKM2 with a biochemically determined AC50 of 10 Nm. It can regulate tumor immune responses by acting on T regulatory cells.
    Formula:C19H22F4N4O3S
    Color and Shape:Solid
    Molecular weight:462.46

    Ref: TM-T77775

    5mg
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  • AKB-6899

    CAS:
    AKB-6899 is an inhibitor of prolyl hydroxylase domain 3 (PHD3) and increases the soluble form of the VEGF receptor (sVEGFR-1) production from GM-CSF-treated
    Formula:C14H11FN2O4
    Purity:97.87%
    Color and Shape:Solid
    Molecular weight:290.25

    Ref: TM-T29797

    1mg
    48.00€
    5mg
    101.00€
    10mg
    163.00€
    25mg
    273.00€
    50mg
    391.00€
    1mL*10mM (DMSO)
    111.00€
  • Pactimibe sulfate

    CAS:
    Pactimibe sulfate is a dual ACAT1/2 inhibitor with anti-atherogenic potential, reducing plasma cholesterol.
    Formula:C50H82N4O10S
    Color and Shape:Solid
    Molecular weight:931.28

    Ref: TM-T62974

    25mg
    1,459.00€
    50mg
    1,900.00€
  • Hydroxy Lenalidomide

    CAS:
    Hydroxy lenalidomide, a metabolite of the thalidomide analog and anticancer agent lenalidomide, is a derivative substance involved in the metabolic process of its parent compound.
    Formula:C13H13N3O4
    Color and Shape:Solid
    Molecular weight:275.26

    Ref: TM-T84989

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  • ALP/Carbonic anhydrase-IN-1

    CAS:
    Compound 1e, also known as ALP/Carbonic anhydrase-IN-1, is a dual inhibitor targeting both carbonic anhydrase (CA) isozymes II, IX, and XII, as well as alkaline
    Formula:C15H16N2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:224.3

    Ref: TM-T83137

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  • GLUT4 activator 1

    CAS:
    GLUT4 activator 1 is a potent glucose transporter type 4 (GLUT4) translocation activator (EC50: 0.14 μM).
    Formula:C23H21FN4O3S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:452.5

    Ref: TM-T11420

    25mg
    1,908.00€
    50mg
    2,502.00€
    100mg
    3,330.00€
  • TID43

    CAS:
    TID43, a CK2 inhibitor, exhibits potent inhibition with an IC50 value of 0.3 μM. It is applicable in anti-angiogenic research [1].
    Formula:C10H3I4NO4
    Color and Shape:Solid
    Molecular weight:708.755

    Ref: TM-T84508

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  • Sulforhodamine 101 DHPE

    CAS:
    Sulforhodamine 101 DHPE, a fluorescent probe, results from the conjugation of sulforhodamine 101, a red fluorescent dye with excitation/emission spectra of 586/605 nm, to the phospholipid 1,2-dipalmitoyl-sn-glycero-3-PE. It effectively integrates into phospholipid bilayers and is utilized for imaging solid supported lipid bilayers, detecting protein-ligand interactions on bilayers, and monitoring lipid probe colocalization in liposomes through resonance energy transfer (RET).
    Formula:C74H117N4O14PS2
    Color and Shape:Solid
    Molecular weight:1381.86

    Ref: TM-T85159

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  • Difamilast

    CAS:
    Difamilast is a selective inhibitor of phosphodiesterase-4 (PDE4) with particularly efficient inhibition of subtype B (IC50=11.2 nM).
    Formula:C23H24F2N2O5
    Purity:99.47% - 99.64%
    Color and Shape:Solid
    Molecular weight:446.44

    Ref: TM-T27172

    1mg
    65.00€
    5mg
    141.00€
    10mg
    222.00€
    25mg
    409.00€
    50mg
    615.00€
    1mL*10mM (DMSO)
    156.00€
  • GPX4-IN-4

    CAS:
    GPX4-IN-4 (Compound 24) serves as a potent inhibitor of GPX4, applicable in cancer research [1].
    Formula:C22H21ClN2O5S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:460.93

    Ref: TM-T74846

    25mg
    1,504.00€
    50mg
    1,963.00€
    100mg
    2,520.00€
  • 5,6-dehydro Arachidonic Acid

    CAS:
    5,6-dehydro Arachidonic acid, an arachidonic acid analog with a 5,6 acetylene, inhibits 5-LO; Ki=15 μM in RBL cells, IC50=10 μM in guinea pig leukocytes.
    Formula:C20H30O2
    Color and Shape:Solid
    Molecular weight:302.45

    Ref: TM-T38067

    25µg
    319.00€
    50µg
    605.00€
    100µg
    1,144.00€
  • Glucocerebrosidase-IN-1 hydrochloride

    CAS:
    Glucocerebrosidase-IN-1 (compound 11a) hydrochloride is a potent, selective GCase (glucocerebrosidase) inhibitor with IC50 and Ki values of 29.3 μM and 18.5 μM
    Formula:C13H28ClNO3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:281.82

    Ref: TM-T78671

    5mg
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  • D-threo-PDMP

    CAS:
    D-threo-PDMP inhibits glucoceramide synthase, cutting cell surface glycosphingolipids and hindering neurite growth.
    Formula:C23H38N2O3
    Color and Shape:Solid
    Molecular weight:390.56

    Ref: TM-T72917

    25mg
    1,639.00€
    50mg
    2,142.00€
    100mg
    2,790.00€
  • h-NTPDase-IN-5

    CAS:
    h-NTPDase-IN-5 (compound 3b) serves as a pan-inhibitor of NTPDase, exhibiting inhibitory concentration 50 (IC50) values of 1.10 μM (h-NTPDase1), 44.73 μM (h-
    Formula:C23H21N3O2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:403.5

    Ref: TM-T79623

    25mg
    1,504.00€
    50mg
    1,963.00€
    100mg
    2,520.00€
  • S-(N-Methylsulfinylbutylthiocarbamoyl)-L-cysteine

    CAS:
    S-(N-Methylsulfinylbutylthiocarbamoyl)-L-cysteine (SFN-Cys) is an isothiocyanate derivative, functioning as an active metabolite of sulforaphane, a class I and
    Formula:C9H18N2O3S3
    Color and Shape:Solid
    Molecular weight:298.45

    Ref: TM-T83898

    5mg
    495.00€
  • JP104

    CAS:
    JP104 is an aryl carbamate that irreversibly inhibits fatty acid amide hydrolase (FAAH) with a pIC50 value of approximately 8 [1].
    Formula:C25H30N2O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:406.52

    Ref: TM-T78593

    5mg
    152.00€
    10mg
    268.00€
    50mg
    1,144.00€
    100mg
    1,963.00€
  • FASN-IN-1

    CAS:
    FASN-in-1 is an effective, specific inhibitor of fatty acid synthase (FASN), a compound specifically designed to target and inhibit the activity of the enzyme
    Formula:C18H25N3O3S2
    Purity:99.92% - >99.99%
    Color and Shape:Solid
    Molecular weight:395.54

    Ref: TM-T11267

    1mg
    57.00€
    5mg
    122.00€
    10mg
    200.00€
    25mg
    340.00€
    50mg
    502.00€
    1mL*10mM (DMSO)
    130.00€
  • IA1-8H2

    CAS:
    IA1-8H2, a non-covalent, non-competitive inhibitor of PHPT1 with an IC50 of 3.4 μM, is utilized in the study of lung cancer, hepatocarcinoma, and renal cancer [
    Formula:C13H12O5
    Color and Shape:Solid
    Molecular weight:248.23

    Ref: TM-T82137

    5mg
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  • EOS (d18:1/30:0/18:2)

    CAS:
    EOS (d18:1/30:0/18:2) is a lipid molecule that can be used in life science related research. The CAS number of EOS (d18:1/30:0/18:2) is 97040-38-5.
    Formula:C66H125NO5
    Color and Shape:Solid
    Molecular weight:1012.7

    Ref: TM-T85165

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  • GSK321

    CAS:
    GSK321 is an IDH1 inhibitor that prevents cytoplasmic glutamine reductive carboxylation.GSK321 is used in the study of leukemia.
    Formula:C28H28FN5O3
    Purity:99.73%
    Color and Shape:Solid
    Molecular weight:501.55

    Ref: TM-T32009

    2mg
    139.00€
  • cis-Clopidogrel-MP derivative

    CAS:
    cis-Clopidogrel-MP derivative, also Clopidogrel-MP-AM, is a 3'-methoxyacetophenone Clopidogrel metabolite and oral P2Y12 receptor platelet inhibitor.
    Formula:C25H26ClNO6S
    Color and Shape:Solid
    Molecular weight:503.99

    Ref: TM-T38506

    1mg
    1,074.00€
  • Δ2-trans-Hexadecenoic Acid

    CAS:
    Cismonoenoic acids form readily from unsaturated fatty acids in animal tissues, with palmitoleic acid (9-cis-hexadecenoic acid) deriving from palmitic acid. An intermediate, 1Δ2-trans-hexadecenoic acid, arises during the β-oxidation of palmitic acid. Furthermore, Δ2-trans-hexadecenoic acid, at a dose of 10 mg/kg, significantly reduces gastric juice secretion in pylorus-ligated rats, indicating potential for gastric ulceration simulation models.
    Formula:C16H30O2
    Color and Shape:Solid
    Molecular weight:254.4

    Ref: TM-T84475

    10mg
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    100mg
    1,309.00€
  • 1,2-Dilinoleoyl-3-α-Linolenoyl-rac-glycerol

    CAS:
    1,2-Dilinoleoyl-3-α-linolenoyl-rac-glycerol is a triacylglycerol featuring linoleic acid at the sn-1 and sn-2 positions and α-linolenic acid at the sn-3 position, identified within corn and soybean oils.
    Formula:C57H96O6
    Color and Shape:Solid
    Molecular weight:877.37

    Ref: TM-T85095

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  • 7-hydroxy Etodolac

    CAS:
    7-Hydroxy Etodolac, an inactive metabolite of the non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor etodolac, serves no active function in the drug's pharmacological effects.
    Formula:C17H21NO4
    Color and Shape:Solid
    Molecular weight:303.35

    Ref: TM-T84948

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  • MetAP2-IN-1

    CAS:
    MetAP2-IN-1 is a selective inhibitor of MetAP2, a target involved in angiogenesis-related conditions, suitable for research applications [1].
    Formula:C8H6BrN3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:224.06

    Ref: TM-T78129

    5mg
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  • Indeloxazine

    CAS:
    Indeloxazine is a cerebral activator and anticonvulsant.
    Formula:C14H17NO2
    Color and Shape:Solid
    Molecular weight:231.29

    Ref: TM-T69007

    25mg
    1,908.00€
    50mg
    2,502.00€
    100mg
    3,330.00€
  • MLS000545091

    CAS:
    MLS000545091 is a potent and selective human epithelial 15-lipoxygenase-2 mixed-type inhibitor.
    Formula:C14H15ClN2O
    Purity:99.84%
    Color and Shape:Solid
    Molecular weight:262.73

    Ref: TM-T24488

    1mg
    60.00€
    2mg
    82.00€
    5mg
    119.00€
    10mg
    178.00€
    25mg
    313.00€
    50mg
    445.00€
    100mg
    587.00€
    200mg
    800.00€
  • R-1663

    CAS:
    R-1663 inhibits factor Xa, prolongs clotting, reduces thrombin without affecting bleed time; more effective on peak than ETP.
    Formula:C24H21ClF3N5O3
    Color and Shape:Solid
    Molecular weight:519.9

    Ref: TM-T28491

    25mg
    1,773.00€
    50mg
    2,322.00€
    100mg
    3,060.00€
  • 11(Z),14(Z),17(Z)-Eicosatrienoic Acid methyl ester

    CAS:
    11(Z),14(Z),17(Z)-Eicosatrienoic acid methyl ester is the ester derivative of 11(Z),14(Z),17(Z)-eicosatrienoic acid, identified within lipid-producing microalgae Nannochloropsis, as well as in diesel-contaminated soils and residential wastewater.
    Formula:C21H36O2
    Color and Shape:Solid
    Molecular weight:320.517

    Ref: TM-T84417

    10mg
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  • Chinese gallotannin

    CAS:
    Chinese gallotannin, a non-specific promiscuous inhibitor of α-amylase, exhibits a K(i) value of 0.82 μg/mL against human salivary α-amylase and shows potential
    Formula:C76H52O46
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1701.2

    Ref: TM-T78627

    5mg
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  • 6,9,12,15-Hexadecatetraenoic acid-ethyl ester

    CAS:
    6,9,12,15-Hexadecatetraenoic acid-ethyl ester, an n-1PUFA, demonstrates oral activity and has been shown to lower plasma triglyceride levels in mice when
    Formula:C18H28O2
    Color and Shape:Solid
    Molecular weight:276.41

    Ref: TM-T83275

    2mg
    1,161.00€
  • IDH889

    CAS:
    IDH889: Brain-penetrant, mutant-specific IDH1 inhibitor; selective for IDH1 R132* mutations. IC50: 0.02μM (R132H), 0.072μM (R132C), 1.38μM (wild-type).
    Formula:C23H25FN6O2
    Purity:≥98%
    Color and Shape:Solid
    Molecular weight:436.48

    Ref: TM-T15551

    1mg
    98.00€
    5mg
    222.00€
    1mL*10mM (DMSO)
    245.00€
  • 3β,5α,6β-Trihydroxycholanic Acid

    CAS:
    3β,5α,6β-Trihydroxycholanic acid, a metabolite derived from 5α,6β-dihydroxycholestanol, exhibits elevated levels in dried blood spots of patients diagnosed with Niemann-Pick disease type C, a neurodegenerative disorder characterized by the accumulation of cholesterol and sphingolipids in lysosomes.
    Formula:C24H40O5
    Color and Shape:Solid
    Molecular weight:408.6

    Ref: TM-T84988

    10mg
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  • 11β-Prostaglandin F2α Ethanolamide

    CAS:
    11β-Prostaglandin F2αethanolamide (11β-PGF2α-EA), posited as the hepatic metabolite derived from PGD2-EA during COX-2 metabolism of AEA—an endogenous cannabinoid present in brain, liver, and various mammalian tissues—is synthesized directly from AEA via COX-2 and specific prostaglandin synthase, leading to ethanolamide versions of classical prostaglandins. Additionally, PGD2-EA formation occurs in activated RAW 264.7 cells upon AEA treatment.
    Formula:C22H39NO5
    Color and Shape:Solid
    Molecular weight:397.6

    Ref: TM-T84655

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  • CAY10435

    CAS:
    CAY10435, a β-ketooxazapyridine and selective FAAH inhibitor, exhibits antimicrobial properties. It binds non-competitively to the FAAH of Dictyostelium discoideum, demonstrating a Kd value of 0.57 nM [1] [2].
    Formula:C18H26N2O2
    Color and Shape:Solid
    Molecular weight:302.41

    Ref: TM-T84554

    10mg
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  • Sch59498

    CAS:
    Sch59498 is a potent phosphodiesterase 1c (Pde1c) inhibitor.
    Formula:C17H25N5O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:315.41

    Ref: TM-T12869

    25mg
    1,639.00€
    50mg
    2,142.00€
    100mg
    2,790.00€
  • ZK824190

    CAS:
    ZK824190: oral uPA inhibitor, IC50 - uPA 237 nM, tPA 1600 nM, Plasmin 1850 nM.
    Formula:C22H20F2N2O4
    Purity:98.84%
    Color and Shape:Solid
    Molecular weight:414.4

    Ref: TM-T13408

    1mg
    152.00€
    5mg
    306.00€
    10mg
    442.00€
    25mg
    675.00€
    50mg
    900.00€
    100mg
    1,224.00€
    1mL*10mM (DMSO)
    318.00€
  • MK-8666

    CAS:
    MK-8666, a partial GPCR agonist targeting GPR40, may treat type 2 diabetes by enhancing insulin secretion and lowering glucose safely.
    Formula:C29H31NO6S
    Color and Shape:Solid
    Molecular weight:521.62

    Ref: TM-T70468

    25mg
    3,574.00€
    50mg
    4,995.00€
    100mg
    6,741.00€
  • 12(Z),15(Z)-Heneicosadienoic Acid

    CAS:
    12(Z),15(Z)-Heneicosadienoic acid, an ω-6 very long-chain polyunsaturated fatty acid, serves as a positional isomer of heneicosadienoic acid, which is scarcely found in living organisms.
    Formula:C21H38O2
    Color and Shape:Solid
    Molecular weight:322.533

    Ref: TM-T85287

    10mg
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    50mg
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  • ICMT-IN-47

    CAS:
    ICMT-IN-47 (compound 26) acts as an ICMT inhibitor with an IC50 value of 0.76 μM [1].
    Formula:C25H35NO
    Color and Shape:Solid
    Molecular weight:365.55

    Ref: TM-T82095

    5mg
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    50mg
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  • 1,2,3-Tripentadecanoyl Glycerol

    CAS:
    1,2,3-Tripentadecanoyl glycerol, a triacylglycerol featuring pentadecanoic acid at the sn-1, sn-2, and sn-3 positions, occurs in various grapes. It serves as a standard in LC-MS for detecting triacylglycerols in human plasma.
    Formula:C48H92O6
    Color and Shape:Solid
    Molecular weight:765.24

    Ref: TM-T85115

    10mg
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  • ICMT-IN-53

    CAS:
    ICMT-IN-53 (compound 12) is an ICMT inhibitor exhibiting an IC50 of 0.96 μM, alongside favorable PAMPA permeability and antiproliferative properties.
    Formula:C26H36FN3
    Color and Shape:Solid
    Molecular weight:409.58

    Ref: TM-T82089

    5mg
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    50mg
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  • LY433771

    CAS:
    LY433771 is a compound that inhibits the activity of Type X secretory phospholipase A2.
    Formula:C22H24N2O4
    Color and Shape:Solid
    Molecular weight:380.44

    Ref: TM-T84972

    10mg
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    50mg
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  • 1-Palmitoyl-2-Linoleoyl-sn-glycero-3-PC

    CAS:
    1-Palmitoyl-2-Linoleoyl-sn-glycero-3-phosphatidylcholine (PC) is a phospholipid characterized by the incorporation of palmitic (16:0) and linoleic (18:2) acids at the sn-1 and sn-2 positions, respectively. It is utilized in the creation of micelles, liposomes, and various artificial membranes, playing a significant role in research on lipid peroxidation.
    Formula:C42H80NO8P
    Color and Shape:Solid
    Molecular weight:758.075

    Ref: TM-T84375

    10mg
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    50mg
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  • Metformin hydroxy analog 2

    CAS:
    Metformin hydroxy analog 2, an oxidation product of the biguanide metformin (1), represents a chemically transformed variant of the original compound, showcasing a modified molecular structure through the process of oxidation.
    Formula:C4H10N4O
    Color and Shape:Solid
    Molecular weight:130.15

    Ref: TM-T84939

    10mg
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    50mg
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  • sEH/AChE-IN-3

    CAS:
    sEH/AChE-IN-3 -15: potent dual sEH & AChE inhibitor; crosses BBB; IC50: hsEH 0.4nM, hAChE 1.94nM, hBChE 615nM, msEH 4.3nM, mAChE 2.61nM.
    Formula:C35H39ClF3N5O3
    Color and Shape:Solid
    Molecular weight:670.16

    Ref: TM-T72875

    25mg
    1,639.00€
    50mg
    2,142.00€
    100mg
    2,790.00€
  • 17(R)-Resolvin D3

    CAS:
    17(R)-Resolvin D3 (17(R)-RvD3) is an aspirin-triggered epimer of resolvin D3, produced from docosahexaenoic acid (DHA) through the action of COX-2 in the presence of aspirin, via a 17(R)-hydroperoxy DHA (17(R)-HDHA) intermediary. Identified in mouse inflammatory exudates, 17(R)-RvD3 notably inhibits the transmigration of isolated human polymorphonuclear cells (PMNs) and fosters the efferocytosis of apoptotic PMNs by macrophages. Furthermore, in a mouse model of zymosan-induced peritonitis, 17(R)-RvD3 administration (10 ng/animal) significantly curtails neutrophil infiltration into the peritoneal cavity and modulates cytokine levels by reducing IL-6 and increasing IL-10 in the inflammatory exudate. It engages GPR32, evidenced by activation in a β-arrestin reporter assay and augments phagocytosis more effectively in CHO cells overexpressing GPR32 compared to controls. Additionally, 17(R)-RvD3 enhances the clearance of etoposide-induced tumor cell debris by monocyte-derived macrophages in H460 human lung carcinoma.
    Formula:C22H32O5
    Color and Shape:Solid
    Molecular weight:376.49

    Ref: TM-T85108

    10mg
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    50mg
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  • N-desethyl-N-methyl Vardenafil

    CAS:
    N-Desethyl-N-methyl Vardenafil, a potential impurity in commercial vardenafil preparations, functions as a phosphodiesterase 5 (PDE5) inhibitor, similar to its parent compound. With an IC50 value of 2 nM, it exhibits potent inhibitory activity against PDE5.
    Formula:C22H30N6O4S
    Color and Shape:Solid
    Molecular weight:474.58

    Ref: TM-T84929

    10mg
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    50mg
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  • XL041

    CAS:
    XL041 (BMS-852927) is an agonist of LXRβ-selective.
    Formula:C29H28Cl2F2N2O4S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:609.51

    Ref: TM-T14679

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    1mL*10mM (DMSO)
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  • (+/-)- Adomeglivant

    CAS:
    Adomeglivant (LY2409021) is a potent glucagon receptor blocker, reducing blood glucose in type 2 diabetes with minimal side effects.
    Formula:C32H36F3NO4
    Color and Shape:Solid
    Molecular weight:555.63

    Ref: TM-T68471

    25mg
    1,773.00€
    50mg
    2,322.00€
    100mg
    3,060.00€
  • Dendrogenin A

    CAS:
    Dendrogenin A (DDA) is a compound acting as a selective liver X receptor (LXR) modulator, cholesterol epoxide hydrolase inhibitor (Ki = 120 nM), and a metabolic
    Formula:C32H55N3O2
    Color and Shape:Solid
    Molecular weight:513.80

    Ref: TM-T83765

    1mg
    105.00€
    5mg
    325.00€
    10mg
    600.00€
  • C82

    CAS:
    C82 acts as an inhibitor of Mycobacterium tuberculosis (Mtb) cyclic dinucleotide phosphodiesterase (CdnP), with an IC50 value of 17.5 µM. This particular enzyme is responsible for breaking down cyclic di-AMP (c-di-AMP) into adenosine 5'-monophosphate (AMP). Notably, C82 demonstrates selectivity for Mtb CdnP over other bacterial cyclic dinucleotide phosphodiesterases (CDN PDEs) such as Yybt, RocR, and Group B Streptococcus (GBS) CdnP, as well as the mammalian CDN PDE ENPP1, and the viral CDN PDE poxin, showing effectiveness at a concentration of 200 µM.
    Formula:C17H17N3O3S
    Color and Shape:Solid
    Molecular weight:343.4

    Ref: TM-T84965

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  • HSD17B13-IN-3

    CAS:
    HSD17B13-IN-3 (compound 2) is a potent inhibitor of hydroxysteroid 17ß-dehydrogenase 13 (HSD17B13), lacking cellular experimental activity [1].
    Formula:C22H21NO6S2
    Color and Shape:Solid
    Molecular weight:459.54

    Ref: TM-T79886

    5mg
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  • 1-Deazaadenosine

    CAS:
    1-Deazaadenosine, an adenosine deaminase inhibitor (Ki: 0.66 μM), may treat cancer, particularly lymphoproliferative disorders.
    Formula:C11H14N4O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:266.25

    Ref: TM-T10015

    10mg
    1,108.00€
  • Therapeutic agent-1

    CAS:
    Therapeutic Agent-1, a heteroaryl compound, serves as an enzyme replacement therapy to enhance glucocerebrosidase activity in the treatment of Gaucher disease [
    Formula:C18H20N6
    Color and Shape:Solid
    Molecular weight:320.39

    Ref: TM-T80994

    5mg
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  • NTE-122

    CAS:
    NTE-122 is a competitive Acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor.
    Formula:C38H59ClN6O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:667.38

    Ref: TM-T25891

    25mg
    1,773.00€
    50mg
    2,322.00€
    100mg
    3,060.00€
  • CKD-519

    CAS:
    CKD-519: A CETP inhibitor with an IC50 of 2.3 nM, blocking cholesteryl ester transfer in serum.
    Formula:C31H34F7NO3
    Color and Shape:Solid
    Molecular weight:601.6

    Ref: TM-T14976

    25mg
    1,459.00€
    50mg
    1,900.00€
    100mg
    2,790.00€
  • MGAT2-IN-4

    CAS:
    MGAT2-IN-4 (compound 33) serves as a monoacylglycerol acyltransferase 2 (MGAT2) inhibitor, exhibiting liver metabolic stability.
    Formula:C27H27N5O
    Color and Shape:Solid
    Molecular weight:437.54

    Ref: TM-T81802

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  • Sampatrilat

    CAS:
    Sampatrilat, an oral vasopeptidase inhibitor, more potently blocks C-domain ACE (Ki=13.8 nM) over N-domain (Ki=171.9 nM).
    Formula:C26H40N4O9S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:584.68

    Ref: TM-T16840

    25mg
    1,639.00€
    50mg
    2,142.00€
    100mg
    2,790.00€
  • 17(S)-HpDHA

    CAS:
    17(S)-HpDHA, primarily produced by the 15-Lipoxygenase (LOX) isoenzymes h15-LOX-1 and h15-LOX-2 from docosahexaenoic acid (DHA), is a key regulator in epoxide synthesis through allosteric modulation. Additionally, it effectively inhibits platelet aggregation, demonstrating an EC50 of approximately 1 μM [1].
    Formula:C22H32O4
    Color and Shape:Solid
    Molecular weight:360.49

    Ref: TM-T84487

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  • 1-Aminodecylidene bis-Phosphonic Acid

    CAS:
    1-Aminodecylidenebis-phosphonic acid, with its potent inhibitory effect on acid sphingomyelinase (IC50= 20 nM), shows selectivity by being less effective against neutral sphingomyelinase (IC50= >100 μM). Additionally, it entirely prevents dexamethasone-induced apoptosis in HepG2 cells.
    Formula:C10H25NO6P2
    Color and Shape:Solid
    Molecular weight:317.26

    Ref: TM-T84472

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  • TMP780

    CAS:
    TMP780 is an inverse RORγt agonist (IC50: 13 nM). RORγt is a tractable drug target for the treatment of cutaneous inflammatory disorders.
    Formula:C31H30N2O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:494.58

    Ref: TM-T13172

    25mg
    1,459.00€
    50mg
    1,900.00€
    100mg
    2,790.00€
  • Niraxostat

    CAS:
    Niraxostat (Y-700) is one of the isocytosine derivatives as xanthine oxidase inhibitors.
    Formula:C16H17N3O3
    Purity:98.13%
    Color and Shape:Solid
    Molecular weight:299.32

    Ref: TM-T33676

    1mg
    118.00€
    5mg
    233.00€
    10mg
    358.00€
    25mg
    587.00€
    50mg
    835.00€
    100mg
    1,108.00€
    1mL*10mM (DMSO)
    219.00€
  • FAAH/cPLA2α-IN-1

    CAS:
    FAAH/cPLA2α-IN-1 is a compound that simultaneously inhibits both FAAH and cPLA2α, demonstrating potent activity with half-maximal inhibitory concentrations (
    Formula:C19H26N4O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:390.43

    Ref: TM-T82421

    5mg
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  • Yonkenafil

    CAS:
    Yonkenafil, a PDE5 inhibitor, may reduce stroke damage and aid in Alzheimer's treatment.
    Formula:C24H33N5O4S
    Color and Shape:Solid
    Molecular weight:487.61

    Ref: TM-T68665

    25mg
    1,026.00€
    50mg
    1,341.00€
    100mg
    2,125.00€
  • ICMT-IN-39

    CAS:
    ICMT-IN-39, also known as compound 18, functions as an inhibitor of ICMT with an IC50 value of 0.031 µM [1].
    Formula:C22H29NO
    Color and Shape:Solid
    Molecular weight:323.47

    Ref: TM-T82104

    5mg
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  • ICMT-IN-50

    CAS:
    ICMT-IN-50 (compound 3) serves as an inhibitor of ICMT with an IC50 value of 0.31 µM [1].
    Formula:C27H31NO3
    Color and Shape:Solid
    Molecular weight:417.54

    Ref: TM-T82092

    5mg
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  • Diflumidone sodium

    CAS:
    Diflumidone sodium is a non-steroidal agent with anti-inflammatory activity.
    Formula:C14H10F2NNaO3S
    Color and Shape:Solid
    Molecular weight:333.29

    Ref: TM-T27173

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • 244cis

    CAS:
    244cis, an ionizable cationic lipid incorporating a piperazine structure, facilitates the creation of lipid nanoparticles (LNPs). These LNPs, when formulated with 244cis and coated with an mRNA reporter gene, exhibit preferential accumulation in the lungs of mice, in contrast to those formulated with SM-102. Additionally, it leads to a reduction in the levels of serum chemokine (C-C motif) ligand 2 (CCL2) [1].
    Formula:C60H111N3O6
    Color and Shape:Solid
    Molecular weight:970.54

    Ref: TM-T84669

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  • 1-Linoleoyl-3-α-Linolenoyl-rac-glycerol

    CAS:
    1-Linoleoyl-3-α-linolenoyl-rac-glycerol, a diacylglycerol, features linoleic acid at the sn-1 position and α-linolenic acid at the sn-3 position. This compound is identified in olive oil that has undergone lipase-catalyzed glycerolysis, utilizing immobilized lipase B derived from C. antarctica.
    Formula:C39H66O5
    Color and Shape:Solid
    Molecular weight:614.94

    Ref: TM-T85092

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  • RP 70676

    CAS:
    RP 70676 is a potent ACAT inhibitor(rat and rabbit ACAT with IC50 of 25 and 44 nM ).
    Formula:C25H28N4S
    Purity:99.92%
    Color and Shape:Solid
    Molecular weight:416.58

    Ref: TM-T12767

    1mg
    58.00€
    5mg
    128.00€
    10mg
    187.00€
    25mg
    338.00€
    50mg
    475.00€
    100mg
    665.00€
    200mg
    893.00€
    1mL*10mM (DMSO)
    141.00€
  • KCL-286

    CAS:
    KCL-286 is an available and potent retinoic acid receptor beta agonist for the amelioration of spinal cord injury (SCI).
    Formula:C19H14N2O4
    Purity:99.93%
    Color and Shape:Solid
    Molecular weight:334.33

    Ref: TM-T78575

    1mg
    59.00€
    5mg
    129.00€
    10mg
    200.00€
    25mg
    421.00€
    50mg
    675.00€
    100mg
    909.00€
    200mg
    1,224.00€
  • GNE-783

    CAS:
    GNE-783 is a selective inhibitor of CHK1.
    Formula:C22H20N6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:368.43

    Ref: TM-T27424

    25mg
    1,639.00€
    50mg
    2,142.00€
    100mg
    2,790.00€
  • PDE7-IN-3

    CAS:
    PDE7-IN-3 (Example 2) serves as an inhibitor of phosphodiesterase PDE7 and exhibits potential analgesic properties.
    Formula:C18H21ClN2O4
    Color and Shape:Solid
    Molecular weight:364.82

    Ref: TM-T78559

    25mg
    1,639.00€
    50mg
    2,142.00€
    100mg
    2,790.00€
  • hMAO-B-IN-32

    CAS:
    hMAO-B-IN-32 is a potent hMAO-B selective inhibitor with an IC50 of 45.52 μM.
    Formula:C16H19NO4
    Purity:99.97%
    Color and Shape:Solid
    Molecular weight:289.33

    Ref: TM-T78232

    1g
    33.00€
  • Leramistat

    CAS:
    Leramistat is a mitochondrial complex I (NIC1) inhibitor that alters cellular metabolism and reduces proliferation in human primary lung fibroblasts.
    Formula:C20H21ClN2O3S
    Purity:98.51%
    Color and Shape:Solid
    Molecular weight:404.91

    Ref: TM-T78208

    2mg
    146.00€
  • AZD7687

    CAS:
    AZD7687: Selective DGAT1 inhibitor, IC50 of 80 nM. In vitro reduces postprandial TAG. In vivo significant GI side effects at >5 mg/day dose.
    Formula:C21H25N3O3
    Color and Shape:Solid
    Molecular weight:367.44

    Ref: TM-T14382

    25mg
    775.00€
    50mg
    1,009.00€
    100mg
    1,521.00€
  • (R)-Azasetron besylate

    CAS:
    (R)-Azasetron besylate (SENS-401), an orally active calcineurin inhibitor, has been shown to mitigate cisplatin-induced hearing loss and cochlear damage [1][2].
    Formula:C23H26ClN3O6S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:507.99

    Ref: TM-T78217

    2mg
    125.00€
  • LB-60-OF61

    CAS:
    LB-60-OF61 is a NAMPT inhibitor, a NAMPT inhibitor that displays antiproliferative activity against MYC oncogene-dependent cancer cell lines.
    Formula:C29H30N6O2
    Purity:99.47%
    Color and Shape:Solid
    Molecular weight:494.59

    Ref: TM-T11823

    1mg
    154.00€
    5mg
    371.00€
    10mg
    612.00€
    25mg
    1,189.00€
    50mg
    2,008.00€
    100mg
    3,132.00€
    1mL*10mM (DMSO)
    404.00€
  • SMS1-IN-1

    CAS:
    SMS1-IN-1 is a potent inhibitor of sphingomyelin synthase 1 (SMS1, IC50 = 2.1 μM), and can be used in the atherosclerosis studies.
    Formula:C23H23BrN2O4S
    Purity:99.81%
    Color and Shape:Solid
    Molecular weight:503.41

    Ref: TM-T12937

    1mg
    71.00€
    5mg
    152.00€
    10mg
    205.00€
    25mg
    334.00€
    50mg
    530.00€
    100mg
    782.00€
    200mg
    1,054.00€
    1mL*10mM (DMSO)
    169.00€
  • AalphaC

    CAS:
    AalphaC (2-Amino-alpha-carboline) is a potential carcinogen.
    Formula:C11H9N3
    Purity:99.32%
    Color and Shape:Crystalline Solid
    Molecular weight:183.21

    Ref: TM-T20889

    25mg
    34.00€
    50mg
    To inquire
    1mL*10mM (DMSO)
    34.00€
  • JGB-1-155

    CAS:
    JGB-1-155, serving as a positive allosteric modulator (N-PAMs), effectively enhances the activity of nicotinamide phosphoribosyltransferase (NAMPT) with an EC 50 of 3.29 μM. It mitigates oxidative stress by elevating NAD+ levels in THP-1 human monocytes and reduces TNFα-induced reactive oxygen species (ROS) in HT-22 cells [1].
    Formula:C26H38N2O3
    Color and Shape:Solid
    Molecular weight:426.59

    Ref: TM-T86767

    25mg
    1,458.00€
    50mg
    1,839.00€
    100mg
    2,322.00€
  • GCase modulator-1

    CAS:
    GCase Modulator-1 (Compound 9g), a quinazoline derivative, functions as a glucosidase modulator with an AC50 value of 2.23 µM [1].
    Formula:C22H18N4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:338.41

    Ref: TM-T82330

    5mg
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  • Z-Pro-Pro-CHO

    CAS:
    Z-Pro-Pro-CHO acts as a prolyl oligopeptidase inhibitor with half-maximal inhibitory concentrations (IC50) of 0.16 μM for human prolyl oligopeptidase and 0.01
    Formula:C18H22N2O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:330.38

    Ref: TM-T78619

    5mg
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    50mg
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  • GSK2324

    CAS:
    GSK2324 is a potent FXR agonist for the treatment of NAFLD by controlling hepatic lipids through reduced uptake and selective reduction of fatty acid synthesis.
    Formula:C29H22Cl2N2O4
    Purity:98.09% - 99.02%
    Color and Shape:Solid
    Molecular weight:533.4

    Ref: TM-T27460

    1mg
    308.00€
    5mg
    745.00€
    10mg
    1,018.00€
    25mg
    1,513.00€
    50mg
    2,062.00€
    100mg
    2,673.00€
  • AZD-1656

    CAS:
    AZD-1656 is a glucokinase activator (GKA) that can cause dose-limiting hypoglycemia in normal animals used in embryofetal development studies and type 2
    Formula:C24H26N6O5
    Purity:97.07% - 99.37%
    Color and Shape:Solid
    Molecular weight:478.5

    Ref: TM-T26712

    1mg
    92.00€
    2mg
    120.00€
    5mg
    188.00€
    10mg
    311.00€
    25mg
    628.00€
    50mg
    944.00€
    1mL*10mM (DMSO)
    205.00€
  • N-Formyl-L-histidine

    CAS:
    N-Formyl-L-histidine is a competitive inhibitor of L-histidine deaminase (Ki = 4.26 mM) and also binds to histidine-tRNA synthetase (Ki = 4.6 μM).
    Formula:C7H9N3O3
    Purity:99.91%
    Color and Shape:Solid
    Molecular weight:183.16

    Ref: TM-T81677

    5mg
    38.00€
    10mg
    49.00€
    25mg
    79.00€
    50mg
    101.00€
    100mg
    150.00€
    500mg
    355.00€
  • 1-Stearoyl-2-Palmitoyl-3-Oleoyl-rac-glycerol

    CAS:
    1-Stearoyl-2-palmitoyl-3-oleoyl-rac-glycerol is a triacylglycerol comprising stearic acid (at the sn-1 position), palmitic acid (at the sn-2 position), and oleic acid (at the sn-3 position), identified in bovine milk.
    Formula:C55H104O6
    Color and Shape:Solid
    Molecular weight:861.41

    Ref: TM-T85086

    10mg
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    50mg
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  • MR-2-93-3

    CAS:
    MR-2-93-3, a long-chain fatty acid, functions as a carrier for polynucleotides [1].
    Formula:C89H150N2O8
    Color and Shape:Solid
    Molecular weight:1376.15

    Ref: TM-T84667

    10mg
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    50mg
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  • Eprinomectin B1a

    CAS:
    Eprinomectin B1a, composing over 90% of the antiparasitic agent eprinomectin, is a primary component alongside eprinomectin B1b, which constitutes less than 10%. This compound is part of the avermectin family, used as insecticides and anthelmintics.
    Formula:C50H75NO14
    Color and Shape:Solid
    Molecular weight:914.143

    Ref: TM-T85221

    10mg
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    50mg
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  • 12-SAHSA

    CAS:
    Branched fatty acid esters of hydroxy fatty acids (FAHFAs) are lipids recently discovered to be modulated by dietary influences such as fasting and high-fat feeding, and they play a role in enhancing insulin sensitivity. These compounds typically feature a carbon-16 or carbon-18 fatty acid (e.g., palmitoleic, palmitic, oleic, or stearic acid) esterified to a carbon-16 or carbon-18 hydroxy fatty acid. A specific example is 12-SAHSA, which consists of stearic acid linked to 12-hydroxy stearic acid. Notably, 12-SAHSA levels are found to be moderately increased in the serum of glucose tolerant AG4OX mice, a model characterized by adipose tissue-specific overexpression of the Glut4 glucose transporter.
    Formula:C36H70O4
    Color and Shape:Solid
    Molecular weight:566.952

    Ref: TM-T84432

    10mg
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    50mg
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  • ICMT-IN-11

    CAS:
    ICMT-IN-11 (compound 48) serves as an ICMT inhibitor with an IC50 value of 0.031 μM [1].
    Formula:C22H27F2NO2
    Color and Shape:Solid
    Molecular weight:375.45

    Ref: TM-T82134

    5mg
    To inquire
    50mg
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  • 12-OAHSA

    CAS:
    Branched fatty acid esters of hydroxy fatty acids (FAHFAs) are recently discovered lipids that play a role in the body's response to fasting and high-fat diets, with a link to insulin sensitivity. These compounds consist of a long-chain fatty acid (such as palmitoleic, palmitic, oleic, or stearic acid) bonded to a hydroxy fatty acid, both ranging in length from C-16 to C-18. Specifically, 12-OAHSA is a type of FAHFA where oleic acid is attached to the 12th carbon of hydroxy stearic acid. Within the FAHFA family, OAHSAs are particularly notable for their high concentration in the serum of AG4OX mice, a strain engineered to express the Glut4 glucose transporter predominantly in their adipose tissue, which demonstrates an enhanced glucose tolerance.
    Formula:C36H68O4
    Color and Shape:Solid
    Molecular weight:564.9

    Ref: TM-T84430

    10mg
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    50mg
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  • ICMT-IN-30

    CAS:
    ICMT-IN-30 (compound 67) is an ICMT inhibitor with an IC50 value of 0.27 μM [1].
    Formula:C19H25NOS
    Color and Shape:Solid
    Molecular weight:315.47

    Ref: TM-T82113

    5mg
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    50mg
    To inquire
  • 13,14-dihydro-16,16-difluoro Prostaglandin E1

    CAS:
    Prostaglandin E1 (PGE1), synthesized through cyclooxygenase-mediated metabolism of dihomo-γ-linolenic acid (DGLA), functions by inhibiting platelet aggregation (IC50= 40 nM) and enhancing vasodilation. Its analog, 13,14-dihydro-16,16-difluoro PGE1, and the metabolite, 13,14-dihydro PGE1, both retain similar anti-aggregatory properties to the original compound. The inclusion of two electron-withdrawing fluorine atoms in 13,14-dihydro-16,16-difluoro PGE1 is believed to increase molecular stability and potentially extend bioavailability by resisting hydrolytic degradation.
    Formula:C20H34F2O5
    Color and Shape:Solid
    Molecular weight:392.484

    Ref: TM-T84513

    10mg
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    50mg
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