
Metabolism
Metabolism inhibitors are compounds that interfere with metabolic pathways, altering the production and utilization of energy within cells. These inhibitors are used to study the regulation of metabolism, the role of metabolic pathways in diseases like cancer and diabetes, and to develop new therapeutic strategies. Metabolism inhibitors can target various enzymes and processes involved in glycolysis, fatty acid oxidation, and other metabolic functions. At CymitQuimica, we offer a wide range of high-quality metabolism inhibitors to support your research in biochemistry, metabolic disorders, and drug development.
Subcategories of "Metabolism"
- AhR(42 products)
- Aminopeptidase(76 products)
- CETP(20 products)
- Carbonic Anhydrase(196 products)
- Casein Kinase(139 products)
- DHFR(30 products)
- Decarboxylase(4 products)
- Dehydrogenase(302 products)
- FAAH(64 products)
- FXR(62 products)
- Factor Xa(87 products)
- Fatty Acid Synthase(37 products)
- Ferroptosis(227 products)
- GR(3 products)
- GSNOR(3 products)
- Glucokinase(56 products)
- HIF/HIF Prolyl-Hydroxylase(146 products)
- HMG-CoA Reductase(34 products)
- Hydroxylase(36 products)
- IDO(84 products)
- LDL(7 products)
- Lipase(107 products)
- Lipid(62 products)
- Lipoxygenase(133 products)
- MAO(85 products)
- MPO(2 products)
- NAMPT(40 products)
- P450(6 products)
- PAI-1(26 products)
- PDE(170 products)
- PED(1 products)
- PKM(17 products)
- PPAR(170 products)
- Phospholipase(85 products)
- ROR(47 products)
- Retinoid Receptor(20 products)
- SGK(10 products)
- Thioredoxin(12 products)
- Transferase(30 products)
- Transporter(43 products)
- UGT(4 products)
- Xanthine Oxidase (XO) Inhibitors(9 products)
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Found 9197 products of "Metabolism"
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11-Dehydro-2,3-Dinor Thromboxane B2
CAS:11-Dehydro-2,3-Dinor Thromboxane B2 is a metabolite of Thromboxane B2 (TXB2), formed by the oxidation of TXB2 via 11-Hydroxy Thromboxane Dehydrogenase.Formula:C18H28O6Color and Shape:SolidMolecular weight:340.41FABP4/5-IN-4
CAS:FABP4/5-IN-4 (compound E1) effectively inhibits FABP 4 and FABP 5, displaying IC50 values of 3.78 μM and 5.72 μM, respectively. It is significant in the management of metabolic disorders such as diabetes mellitus [1].Formula:C26H21F2NO5SColor and Shape:SolidMolecular weight:497.51MR-2-93-3
CAS:MR-2-93-3, a long-chain fatty acid, functions as a carrier for polynucleotides [1].Formula:C89H150N2O8Color and Shape:SolidMolecular weight:1376.1512-SAHSA
CAS:Branched fatty acid esters of hydroxy fatty acids (FAHFAs) are lipids recently discovered to be modulated by dietary influences such as fasting and high-fat feeding, and they play a role in enhancing insulin sensitivity. These compounds typically feature a carbon-16 or carbon-18 fatty acid (e.g., palmitoleic, palmitic, oleic, or stearic acid) esterified to a carbon-16 or carbon-18 hydroxy fatty acid. A specific example is 12-SAHSA, which consists of stearic acid linked to 12-hydroxy stearic acid. Notably, 12-SAHSA levels are found to be moderately increased in the serum of glucose tolerant AG4OX mice, a model characterized by adipose tissue-specific overexpression of the Glut4 glucose transporter.Formula:C36H70O4Color and Shape:SolidMolecular weight:566.952BML-288
CAS:BML-288 is a phosphodiesterase Type II (PDE2) inhibitor that demonstrates no inhibition of 5-lipoxygenase (5-LO) or cyclooxygenase (COX-1).Formula:C14H10N4O3SColor and Shape:SolidMolecular weight:314.321,2-Dioleoyl-3-linoleoyl-rac-glycerol
CAS:1,2-Dioleoyl-3-linoleoyl-rac-glycerol (OOL) is a triglyceride featuring oleic acid at the sn-1 and sn-2 positions and linoleic acid at the sn-3 position. This compound is prevalent in several seed and vegetable oils, such as those from pumpkin seeds, olives, and sesame.Formula:C57H102O6Color and Shape:SolidMolecular weight:883.4G43-C3-TEG
CAS:G43-C3-TEG is a glycosyl-transferase inhibitor that diminishes biofilm formation by inhibiting the synthesis of extracellular polysaccharides (EPS) [1].Formula:C24H27N3O9SColor and Shape:SolidMolecular weight:533.55Anticancer agent 122
CAS:Anticancer agent 122, a potent inhibitor of human lactate dehydrogenase A (h LDHA), exhibits significant anticancer activities, rendering it suitable for use inFormula:C18H15ClN2O2SColor and Shape:SolidMolecular weight:358.84ICMT-IN-40
CAS:ICMT-IN-40 (compound 19) is a potent inhibitor of ICMT, exhibiting an IC50 value of 0.031 μM [1].Formula:C22H29NOColor and Shape:SolidMolecular weight:323.47SHP2-IN-17
CAS:SHP2-IN-17 (compound 192) is a potent inhibitor of SHP2, exhibiting an IC50 of 2 nM and holds potential for use in glioblastoma research [1].Formula:C25H24Cl2N6Color and Shape:SolidMolecular weight:479.4ICMT-IN-45
CAS:ICMT-IN-45 (compound 24) serves as an ICMT inhibitor, demonstrating an IC50 value of 0.132 μM [1].Formula:C24H33NOColor and Shape:SolidMolecular weight:351.52ICMT-IN-27
CAS:ICMT-IN-27, also known as compound 64, is an inhibitor of the enzyme ICMT, demonstrating potent activity with an IC50 value of 0.1 µM [1].Formula:C22H28FNO2Color and Shape:SolidMolecular weight:357.46Hypogeic acid
CAS:Hypogeic acid is isolable from cultures of autotrophic bacteria linked to sulfate accumulation in biofilters [1].Formula:C16H30O2Color and Shape:SolidMolecular weight:254.41Arachidonoyl-N-methyl amide
CAS:Anandamide (AEA), an endogenous cannabinoid, interacts with both central (CB1) and peripheral (CB2) cannabinoid receptors. Its effects are concluded through the cellular uptake and enzymatic breakdown of its amide bond by fatty acid amide hydrolase. Arachidonoyl-N-methyl amide, an analog of anandamide, specifically targets the human CB1 receptor, displaying a binding affinity with a Ki of 60 nM. It completely inhibits rat glial gap junction intercellular communication at a concentration of 50 µM.Formula:C21H35NOColor and Shape:SolidMolecular weight:317.5cis-8-Octadecenoic Acid
CAS:Cis-8-Octadecenoic acid, a monounsaturated fatty acid and isomer of oleic acid, trans-vaccenic acid, trans-petroselinic acid, and cis-petroselinic acid, is present in partially hydrogenated vegetable oil and milk fat.Formula:C18H34O2Color and Shape:SolidMolecular weight:282.46ICMT-IN-4
CAS:ICMT-IN-4 (compound 28) serves as an inhibitor of ICMT, exhibiting an IC50 value of 0.27 μM [1].Formula:C22H29NO2Color and Shape:SolidMolecular weight:339.47GIV3727
CAS:GIV3727, a bitter taste receptor hTAS2R antagonist, inhibits the activation of hTAS2R31 by saccharin and acesulfame potassium, effectively diminishing theFormula:C12H22O2Color and Shape:SolidMolecular weight:198.3G1-OC2-K3-E10
CAS:G1-OC2-K3-E10, an ionizable lipid, facilitates mRNA delivery through lipid nanoparticles (LNPs) [1].Formula:C54H111N5O7Color and Shape:SolidMolecular weight:942.4911-Hexadecenoic Acid
CAS:11-Hexadecenoic acid, a monounsaturated fatty acid, comprises both 11-cis-hexadecenoic acid and 11-trans-hexadecenoic acid. These isoforms are present in ewe milk fat and their concentrations increase when the diet is supplemented with lipids from linseed, sunflower, olive, or fish oils. Additionally, 11-trans-hexadecenoic acid is found in intramuscular fat of both male and female foals. The product is a blend of the 11-cis and 11-trans forms. [Matreya, LLC. Catalog No. 1208]Formula:C16H30O2Color and Shape:SolidMolecular weight:254.411,2-Dioleoyl-3-Docosohexaenoyl-rac-glycerol
CAS:1,2-Dioleoyl-3-docosohexaenoyl-rac-glycerol, a triacylglycerol, consists of oleic acid at the sn-1 and sn-2 positions and docosahexaenoic acid at the sn-3 position. This compound has been identified in human breast milk.Formula:C61H102O6Color and Shape:SolidMolecular weight:931.46Prostaglandin H2
CAS:Prostaglandin H2 (PGH2), initially isolated from the incubation of arachidonic acid with ovine seminal vesicle microsomes, acts as a potent vasoconstrictor. It serves as the precursor for all 2-series prostaglandins (PGs) and thromboxanes (TXs). Moreover, as a TP receptor agonist, PGH2 irreversibly aggregates human platelets at concentrations of 50-100 ng/ml.Formula:C20H32O5Color and Shape:SolidMolecular weight:352.471LNP Lipid-8
CAS:LNP Lipid-8 (11-A-M), an ionizable lipid, is utilized in lipid nanoparticles (LNP) for siRNA delivery to T cells without ligand targeting. When loaded with GFP siRNA (siGFP), it significantly silences the GFP gene in a mouse model [1].Formula:C42H71NO7Color and Shape:SolidMolecular weight:702.02SH-BC-893
CAS:SH-BC-893: Oral anti-cancer sphingolipid analog, prevents ceramide-related mitochondrial issues, and tackles diet-related obesity.Formula:C19H32ClNOColor and Shape:SolidMolecular weight:325.92DPM-1001 trihydrochloride
DPM-1001 trihydrochloride: Potent PTP1B inhibitor, IC50 100 nM, oral, non-competitive, anti-diabetic.Formula:C35H60Cl3N3O3Color and Shape:SolidMolecular weight:677.23α-Glucosidase-IN-11
CAS:α-Glucosidase-IN-11 is a highly permeable competitive inhibitor of α-glucosidase (IC50: 0.56 μM).Formula:C23H20N2O6Color and Shape:SolidMolecular weight:420.41Bemfivastatin hemicalcium
CAS:Bemfivastatin hemicalcium (PPD 10558), an orally active HMG-CoA reductase inhibitor, serves as a lipid-lowering agent.Formula:C34H36FN2O6CaColor and Shape:SolidMolecular weight:607.67sEH/AChE-IN-4
CAS:sEH/AChE-IN-4-15 is a dual sEH and AChE inhibitor crossing the BBB, with IC50s: 3.1 nM (hsEH), 1660 nM (hAChE), 179 nM (hBChE), 14.5 nM (msEH), 102 nM (mAChE).Formula:C35H39ClF3N5O3Color and Shape:SolidMolecular weight:670.16Benzoic acid lithium
CAS:Lithium benzoate, an aromatic alcohol present in numerous plants, commonly serves as an additive in food, beverages, cosmetics, and various other products. This compound exhibits antibacterial and antifungal properties, functioning effectively as a preservative [1].Formula:C7H5LiO2Color and Shape:SolidMolecular weight:128.069-SAHSA
CAS:Branched fatty acid esters of hydroxy fatty acids (FAHFAs) are lipids that are modulated by dietary changes such as fasting and high-fat diets, and they play a role in insulin sensitivity. These compounds generally consist of a fatty acid chain of either 16 or 18 carbons (for example, palmitoleic, palmitic, oleic, or stearic acid) esterified to a similarly long hydroxy fatty acid. One specific FAHFA, 9-SAHSA, features stearic acid esterified at the 9th carbon of hydroxy stearic acid. The concentration of 9-SAHSA is notably increased in the serum of glucose-tolerant AG4OX mice, which specifically express the Glut4 glucose-transporting protein in adipose tissue.Formula:C36H70O4Color and Shape:SolidMolecular weight:566.9PTP1B-IN-20
PTP1B-IN-20: Selective PTP1B inhibitor, IC50=1.05μM; less effective on TCPTP (IC50=78μM), targets type 2 diabetes.Formula:C26H28O15Color and Shape:SolidMolecular weight:580.49BMS-986318
CAS:BMS-986318: potent FXR agonist, EC50=53/350 nM, good ADME, effective in liver disease models, for nonalcoholic steatohepatitis research.Formula:C30H23Cl2F3N4O3Color and Shape:SolidMolecular weight:615.43MK-0736
CAS:MK-0736 is a potent and selective 11β-HSD-1 inhibitor.Formula:C23H30F3N3O2SColor and Shape:SolidMolecular weight:469.56BAY-7081
BAY-7081 is a cyanopyridone-based compound that functions as a potent, selective, and orally active PDE9A inhibitor, demonstrating an inhibition concentration (Formula:C19H27ClN4OColor and Shape:SolidMolecular weight:362.95α-Androst-16-en-3-one
CAS:5α-Androst-16-en-3-one, a mammalian pheromone present in boar saliva, plays a crucial role in facilitating social and sexual interactions by acting as a volatile chemical cue. It is utilized to prime sows in estrus for mating or artificial insemination, underscoring its significance in reproductive behavior. Additionally, this compound is detected in human sweat and urine, where it is involved in studies concerning receptor-mediated odorant detection and the genetic foundations of anosmias, thereby broadening its scope of relevance beyond the animal kingdom.Formula:C19H28OColor and Shape:SolidMolecular weight:272.432BMS-962212
CAS:BMS-962212: reversible, selective FXIa blocker, well-tolerated, quick PD effect, rapid clearance, alters clotting time/activity.Formula:C32H28ClFN8O5Purity:98%Color and Shape:SolidMolecular weight:659.074BAB
CAS:4BAB (compound 29) is an irreversible inhibitor of glyoxalase I (GLO1) and exhibits anticancer activity.Formula:C18H28BrN3O10SColor and Shape:SolidMolecular weight:558.4RORγt modulator 4
CAS:RORγt modulator 4 is a RORγt modulator that regulates IL-17A production activity in cells derived from mouse spleen.Formula:C26H27N3O4SColor and Shape:SolidMolecular weight:477.58AS 183
CAS:AS 183 is an inhibitor of cholesterol acyltransferase (ACAT).Formula:C19H34O3Color and Shape:SolidMolecular weight:310.47CAY10632
CAS:Very long chain polyunsaturated fatty acids (VLCPUFA), notably present in the retina, sperm, and brain, have yet to be fully understood in terms of their biosynthesis and functional roles within these tissues. Recent research, particularly with the elongation of very long-chain FA-4 protein, indicates a distinct function for VLCPUFAs in retinal development and the progression of macular degeneration. CAY10632, a specific C32:6 VLCPUFA, while largely unexplored in its biological activities, is believed to play a role in maintaining normal function of photoreceptor cells in the retina.Formula:C32H52O2Color and Shape:SolidMolecular weight:468.766C22 Phytoceramide (t18:0/22:0)
CAS:C22 Phytoceramide (t18:0/22:0) is a lipid molecule that can be used in life science related research. The CAS number of C22 Phytoceramide (t18:0/22:0) is 164576-03-8.Formula:C40H81NO4Color and Shape:SolidMolecular weight:640.1MLS000545091
CAS:MLS000545091 is a potent and selective human epithelial 15-lipoxygenase-2 mixed-type inhibitor.Formula:C14H15ClN2OPurity:99.84%Color and Shape:SolidMolecular weight:262.73B 581
CAS:B 581 is an inhibitor that specifically blocks farnesylated.Formula:C22H38N4O3S2Purity:98%Color and Shape:SolidMolecular weight:470.69Pentadecanoyl ethanolamide
CAS:Pentadecanoyl ethanolamide, a derivative of the endogenous lipid amides (N-acylethanolamines), demonstrates anticonvulsant efficacy in electroshock-induced seizures in mice, exhibiting minimal toxicity [1].Formula:C17H35NO2Color and Shape:SolidMolecular weight:285.472ICMT-IN-43
CAS:ICMT-IN-43 (compound 22) acts as a potent inhibitor of the enzyme ICMT, exhibiting an inhibitory concentration (IC50) value of 0.04 μM [1].Formula:C23H31NOColor and Shape:SolidMolecular weight:337.5AGN 193109 sodium
CAS:AGN 193109 is a potent antagonist of retinoic acid receptors (RARs; Kd= 2, 2, and 3 nM for RARα, β, and γ, respectively), exhibiting selectivity for RARs over retinoid X receptors (RXRs; Kd= >10,000 nM for human RXRα, β, and γ receptors). This compound effectively reverses cellular morphology changes and growth suppression induced by RAR agonists such as all-trans-RA, 13-cis-RA, and 9-cis-RA in ECE16-1 human endometrial ectocervical epithelial cells, particularly when used at a 10-fold molar excess. Furthermore, AGN 193109 downregulates the expression of cytokeratin K5-8, 13, 14, 16, 17, and 19 genes, indicating inhibition of retinoid action, specifically when co-administered with TTNPB but not as a standalone treatment. In vivo studies demonstrate teratogenic effects, including cleft palate, frontonasal dysplasia, and eye malformations in mouse fetuses following a single oral dose of 1 mg/kg.Formula:C28H23O2NaColor and Shape:SolidMolecular weight:414.5RORγt Inverse agonist 3
CAS:RORγt Inverse agonist 3 is a potent, selective and orally active inverse agonist of RORγ(EC50s of 0.22 μM and 0.15 μM for hRORγ and RORγt (human IL-17 cells),Formula:C29H31Cl2N5O4SPurity:98%Color and Shape:SolidMolecular weight:616.56Chinese gallotannin
CAS:Chinese gallotannin, a non-specific promiscuous inhibitor of α-amylase, exhibits a K(i) value of 0.82 μg/mL against human salivary α-amylase and shows potentialFormula:C76H52O46Purity:98%Color and Shape:SolidMolecular weight:1701.2(+/-)12-HpETE
CAS:(+/-)12-HpETE, a vasodilator, is a 12-hydroxyicosatetraenoic acid produced by lipoxygenase [1].Formula:C20H32O4Color and Shape:SolidMolecular weight:336.47KCA-1490
CAS:KCA-1490 is an inhibitor of dual PDE3/4.Formula:C14H13F3N4O2Purity:98%Color and Shape:SolidMolecular weight:326.27Dieicosanoin
CAS:Dieicosanoin is a diacylglycerol that incorporates arachidic acid, a saturated long-chain fatty acid featuring a 20-carbon backbone. This acid is derivable from sources such as peanut butter and anaerobic fungi [1] [2].Formula:C43H84O5Color and Shape:SolidMolecular weight:681.12 (Monomer)Yonkenafil HCl
CAS:Yonkenafil HCl, a PDE5 inhibitor, is used potentially for the treatment of erectile dysfunction.Formula:C24H34ClN5O4SColor and Shape:SolidMolecular weight:524.088(Z),14(Z)-Eicosadienoic Acid
CAS:8(Z),14(Z)-Eicosadienoic Acid, an ω-8 C20:2 fatty acid, constitutes 0.19% of total fatty acids in human milk. In vivo, it is converted by desaturases into eicosatrienoic acids, known for their potent vasodilator properties. However, the physiological effects of 8(Z),14(Z)-Eicosadienoic Acid remain unexplored.Formula:C20H36O2Color and Shape:SolidMolecular weight:308.506ICMT-IN-53
CAS:ICMT-IN-53 (compound 12) is an ICMT inhibitor exhibiting an IC50 of 0.96 μM, alongside favorable PAMPA permeability and antiproliferative properties.Formula:C26H36FN3Color and Shape:SolidMolecular weight:409.58BMS-185411
CAS:BMS-185411 is a bio-active chemical.Formula:C26H23NO3Color and Shape:SolidMolecular weight:397.471,3-Dipalmitoyl glycero-2-PE
CAS:1,3-Dipalmitoyl glycero-2-phosphatidylethanolamine is a phospholipid incorporating saturated long-chain (16:0) stearic acid at the sn-1 and sn-3 positions, with phosphatidylethanolamine (PE) at the sn-2 position. Phosphatidylethanolamines, critical components of biological membranes, play essential structural and functional roles. Various PE types are instrumental in forming micelles, liposomes, and other synthetic membranes.Formula:C37H74NO8PColor and Shape:SolidMolecular weight:691.972PDE5-IN-42
CAS:PDE5-IN-42 is a selective inhibitor of second-generation phosphodiesterase type 5 (PDE5).Formula:C23H31N7O3Purity:98%Color and Shape:SolidMolecular weight:453.54ICMT-IN-44
CAS:ICMT-IN-44 (compound 23) serves as an ICMT inhibitor with an IC50 value of 0.167 μM [1].Formula:C24H33NOColor and Shape:SolidMolecular weight:351.52Selenocystine
CAS:Selenocystine, a broad-spectrum anticancer agent, effectively induces DNA damage, notably DNA double-strand breaks (DSBs), in HepG2 cells, showcasingFormula:C6H12N2O4Se2Purity:98%Color and Shape:SolidMolecular weight:334.09ICMT-IN-19
CAS:ICMT-IN-19 (compound 53) serves as a potent inhibitor of ICMT, demonstrating an IC50 value of 0.026 μM [1].Formula:C21H26N2O3Color and Shape:SolidMolecular weight:354.44ICMT-IN-46
CAS:ICMT-IN-46 (compound 25) is a potent inhibitor of isoprenylcysteine carboxyl methyltransferase (ICMT), exhibiting an IC50 value of 0.556 μM [1].Formula:C25H35NOColor and Shape:SolidMolecular weight:365.55AMC Arachidonoyl Amide
CAS:Arachidonoyl amide (AMC-AA) is a fatty acid amide among several that serve to quantify fatty acid amide hydrolase (FAAH) activity. FAAH, with its relative lack of selectivity, processes various amide head groups beyond ethanolamine, the head group of its primary endogenous substrate, anandamide (AEA). The interaction of AMC-AA with FAAH leads to the liberation of fluorescent aminomethyl coumarin, which has an absorption peak at 360 nm and emission at 465 nm. This fluorescence release facilitates the rapid and efficient assessment of FAAH activity through the utilization of either a standard cuvette or a microplate fluorometer.Formula:C30H39NO3Color and Shape:SolidMolecular weight:461.6LY-338979
CAS:LY-338979 is an impurity of pemetrexedone.Formula:C20H21N5O7Purity:98%Color and Shape:SolidMolecular weight:443.41YG1702
CAS:YG1702, a potent inhibitor specific to ALDH18A1, suppresses the proliferation of MYCN-amplified neuroblastoma (NB) and reduces MYCN expression.Formula:C23H30N2O7SColor and Shape:SolidMolecular weight:478.56FXR antagonist 1
CAS:"Oral FXR antagonist 1 selectively blocks intestinal FXR, with IC50 of 2.1 μM, aiding in NASH research by improving liver health."Formula:C36H59NO5Color and Shape:SolidMolecular weight:585.86Cholesterylamine
CAS:Cholesterylamine, a cationic lipid, can be incorporated into PLGA to create particles with a charged surface, facilitating its use in drug delivery systems andFormula:C27H47NColor and Shape:SolidMolecular weight:385.67Eucalyptacid A
CAS:Eucalyptacid A, a metabolite with antifungal properties, demonstrates efficacy against Alternaria solani, displaying minimum inhibitory concentrations (MIC)Formula:C17H32O5Color and Shape:SolidMolecular weight:316.431,2-Dilauroyl-sn-glycero-3-PA sodium
CAS:DLPA is a phosphatidic acid (PA) that incorporates the medium-chain lauric acid (12:0).Formula:C27H52O8PNaColor and Shape:SolidMolecular weight:558.66ICMT-IN-50
CAS:ICMT-IN-50 (compound 3) serves as an inhibitor of ICMT with an IC50 value of 0.31 µM [1].Formula:C27H31NO3Color and Shape:SolidMolecular weight:417.54Methyl γ-Linolenyl Fluorophosphonate
CAS:MγLnFP, an analog of methyl arachidonyl fluozophosphonate (MAFP), holds significance in pharmacological research due to its potential as an inhibitor of phospholipases, FAAH, and its role as a CB receptor ligand. However, the properties and effects of the γ-linolenyl variant of MAFP remain to be fully explored.Formula:C19H34FO2PColor and Shape:SolidMolecular weight:344.4519(Z),11(E)-Conjugated Linoleic Acid methyl ester
CAS:9(Z),11(E)-Conjugated Linoleic Acid Methyl Ester, identified in lemon grass (C. flexuosus), serves as a standard for quantifying conjugated linoleic acids in thermally stressed olive oil and trans fats in bakery products. [Matreya, LLC. Catalog No. 1255]Formula:C19H34O2Color and Shape:SolidMolecular weight:294.479N-Desethyl Brinzolamide oxalate
CAS:N-Desethyl Brinzolamide oxalate functions as a dual inhibitor targeting Carbonic anhydrase II and Carbonic anhydrase IV, exhibiting inhibitory concentrations (IC50) of 1.28 nM and 128 nM, respectively [1].Formula:C12H19N3O9S3Color and Shape:SolidMolecular weight:445.49HSD17B13-IN-2
CAS:HSD17B13-IN-2 (compound 1) serves as a potent inhibitor of hydroxysteroid 17ß-dehydrogenase 13 (HSD17B13) with demonstrable activity in cellular experiments [1Formula:C21H23F2NO4Color and Shape:SolidMolecular weight:391.41C16 1-Deoxyceramide (m18:1/16:0)
CAS:C16 1-Deoxyceramide (m18:1/16:0) is a lipid molecule that can be used in life science related research. The CAS number of C16 1-Deoxyceramide (m18:1/16:0) is 1246298-56-5.Formula:C34H67NO2Color and Shape:SolidMolecular weight:521.9ICMT-IN-38
CAS:ICMT-IN-38 (Compound 42) is an ICMT inhibitor, demonstrating an IC50 value of 0.049 μM [1].Formula:C22H28ClNOColor and Shape:SolidMolecular weight:357.922-Myristyldipalmitin
CAS:2-Myristyl dipalmitin (PMP), a triglyceride of palmitic acid, shows potential as a lipid marker for Wilson's disease (WD) [1] [2].Formula:C49H94O6Color and Shape:SolidMolecular weight:779.27ICMT-IN-26
CAS:ICMT-IN-26 (compound 38) acts as an ICMT inhibitor with an IC50 value of 0.36 μM [1].Formula:C21H26ClNOColor and Shape:SolidMolecular weight:343.89MetAP2-IN-1
CAS:MetAP2-IN-1 is a selective inhibitor of MetAP2, a target involved in angiogenesis-related conditions, suitable for research applications [1].Formula:C8H6BrN3Purity:98%Color and Shape:SolidMolecular weight:224.06ICMT-IN-52
CAS:ICMT-IN-52 (compound 44) serves as an ICMT inhibitor with an IC50 value of 0.052 μM [1].Formula:C21H26FNOColor and Shape:SolidMolecular weight:327.44(±)-HIP-A
CAS:(±)-HIP-A is an excitatory amino acid transporter blocker.Formula:C6H8N2O4Purity:98%Color and Shape:SolidMolecular weight:172.14L-hydroxylysine dihydrochloride
CAS:L-hydroxylysine dihydrochloride , is formed by posttranslational hydroxylation of some lysine residues. It is an amino acid, is exclusive to collagen protein.Formula:C6H16Cl2N2O3Purity:98%Color and Shape:SolidMolecular weight:235.11RORγt Inverse agonist 6
CAS:RORγt Inverse agonist 6 is an agonist of RORγt inverse. RORγt Inverse agonist 6 can be used in research on Th17-driven autoimmune diseases.Formula:C28H29ClN6O5Purity:99.52%Color and Shape:SolidMolecular weight:565.02Ref: TM-T12753
1mg62.00€5mg140.00€10mg202.00€25mg324.00€50mg437.00€100mg562.00€200mg743.00€1mL*10mM (DMSO)168.00€ICMT-IN-54
CAS:ICMT-IN-54 (compound 7c), an adamantyl analogue, serves as an ICMT inhibitor with an IC50 value of 12.4 μM, targeting the methylation process facilitated byFormula:C29H45NO3SColor and Shape:SolidMolecular weight:487.74MGAT2-IN-2
CAS:MGAT2-IN-2 is a potent inhibitor of acyl CoA:monoacylglycerol acyltransferase 2 (MGAT2) (IC50 of 3.4 nM).Formula:C26H21F5N4O4SPurity:98%Color and Shape:SolidMolecular weight:580.53L-CCG-lll
CAS:inhibitor of both glial and neuronal uptake of glutamate, aspartate and cysteate.Formula:C6H9NO4Purity:98%Color and Shape:SolidMolecular weight:159.14C14-SPM
CAS:C14-SPM, a branched-chain polyamine lipidoid, facilitates the delivery of siRNA [1].Formula:C94H194N4O6Color and Shape:SolidMolecular weight:1476.57Raloxifene Bismethyl Ether hydrochloride
CAS:Raloxifene Bismethyl Ether hydrochloride is a Raloxifene metabolite and an estrogen receptor inactive compound on which both hydroxyl groups are absent.Formula:C30H32ClNO4SPurity:98%Color and Shape:SolidMolecular weight:538.1C2 Dihydro Ceramide (d18:0/2:0)
CAS:C2 Dihydro Ceramide (d18:0/2:0) (C2 Dihydroceramide) is a ceramide that is a precursor of ceramide synthesis and stimulates ABCA1-mediated cholesterol efflux.Formula:C20H41NO3Purity:98%Color and Shape:SolidMolecular weight:343.544-Methylumbelliferyl-α-D-Glucopyranoside
CAS:4-Methylumbelliferyl-α-D-Glucopyranoside (4MU-αGlc) is a fluorescence substrate for α-glucosidase, serving as a biomarker for Fabry disease and Pompe diseaseFormula:C16H18O8Purity:99.97%Color and Shape:SolidMolecular weight:338.31ICMT-IN-6
CAS:ICMT-IN-6 (compound 29) serves as an inhibitor of isoprenylcysteine carboxyl methyltransferase (ICMT), exhibiting an inhibitory concentration 50 (IC50) value ofFormula:C23H31NO2Color and Shape:SolidMolecular weight:353.5ICMT-IN-34
CAS:ICMT-IN-34 (compound 39) serves as an effective inhibitor of ICMT, exhibiting an IC50 value of 0.17 μM [1].Formula:C21H25Cl2NOColor and Shape:SolidMolecular weight:378.3413-OAHSA
CAS:13-OAHSA, a branched fatty acid ester of hydroxy fatty acids (FAHFAs), results from the esterification of oleic acid to 13-hydroxy stearic acid. It represents a significant component of the FAHFA family, most abundantly expressed in the serum of glucose-tolerant AG4OX mice that exhibit adipose tissue-specific overexpression of the Glut4 glucose transporter. Similar to other FAHFAs which are known to enhance glucose tolerance, stimulate insulin secretion, and exert anti-inflammatory effects, 13-OAHSA may play a pivotal role in managing metabolic syndrome and inflammation.Formula:C36H68O4Color and Shape:SolidMolecular weight:564.9FXIa-IN-7
CAS:FXIa-IN-7 is an orally available, selective and potent inhibitor of factor XIa for the study of thrombophilia.Formula:C28H28N2O4Purity:98.55%Color and Shape:SolidMolecular weight:456.53cKK-E15
CAS:cKK-E15, a peptide-lipid, is instrumental in formulating LNP3 alongside C14PEG2000, unmodified cholesterol, and DOPE [1].Formula:C72H144N4O6Color and Shape:SolidMolecular weight:1161.94C12-113
CAS:C12-113, a lipidoid delivery agent, effectively transfects siRNA into cells and, when combined with additional lipids, forms lipid nanoparticles (LNPs). These LNPs facilitate the delivery of mRNA encoding the spike glycoprotein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in mice [1] [2].Formula:C53H111N3O4Color and Shape:SolidMolecular weight:854.471,2-Dipalmitoyl-sn-glycero-3-N,N-dimethyl-PE
CAS:1,2-Dipalmitoyl-sn-glycero-3-N,N-dimethyl-PE is a derivative of 1,2-dipalmitoyl-sn-glycero-3-PE (1,2-DPPE) with two added methyl groups on its sn-3 moiety, which in aqueous suspensions, reduces the phase transition temperature relative to those of 1,2-DPPE and 1,2-dipalmitoyl-sn-glycero-3-N-methyl-PE (1,2-NMeDPPE). It is utilized in creating liposomes and monolayers for investigating membrane permeability and monolayer viscosity.Formula:C39H78NO8PColor and Shape:SolidMolecular weight:720.026113-O12B
CAS:"113-O12B is an ionizable cationic lipidoid containing a disulfide bond, utilized in the generation of lipid nanoparticles (LNPs) for mRNA delivery [1]."Formula:C57H111N3O8S8Color and Shape:SolidMolecular weight:1223.03COX-2-IN-30
CAS:COX-2-IN-30, a benzenesulfonamide derivative, is an orally active, dual inhibitor of cyclooxygenase-2 (COX-2; IC50 = 49 nM) and cyclooxygenase-1 (COX-1; IC50 =Formula:C17H16N6O3SPurity:98%Color and Shape:SolidMolecular weight:384.41ICMT-IN-31
CAS:ICMT-IN-31 (compound 68) serves as an ICMT inhibitor, demonstrating significant potency with an IC50 value of 0.0038 μM [1].Formula:C19H24ClNOSColor and Shape:SolidMolecular weight:349.921-Palmitoyl-2-Oleoyl-3-Stearoyl-rac-glycerol
CAS:1-Palmitoyl-2-oleoyl-3-stearoyl-rac-glycerol, a primary triacylglycerol in cocoa butter, features palmitic acid (at the sn-1 position), oleic acid (at the sn-2 position), and stearic acid (at the sn-3 position).Formula:C55H104O6Color and Shape:SolidMolecular weight:861.411a,1b-dihomo Prostaglandin F2α
CAS:1a,1b-Dihomo Prostaglandin F2α (1a,1b-dihomo PGF2α), a hypothetical product of adrenic acid in the COX pathway, is predominantly synthesized in the renal medulla, reflecting the selective distribution of adrenic acid in this region.Formula:C22H38O5Color and Shape:SolidMolecular weight:382.541

