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Metabolism

Metabolism

Metabolism inhibitors are compounds that interfere with metabolic pathways, altering the production and utilization of energy within cells. These inhibitors are used to study the regulation of metabolism, the role of metabolic pathways in diseases like cancer and diabetes, and to develop new therapeutic strategies. Metabolism inhibitors can target various enzymes and processes involved in glycolysis, fatty acid oxidation, and other metabolic functions. At CymitQuimica, we offer a wide range of high-quality metabolism inhibitors to support your research in biochemistry, metabolic disorders, and drug development.

Subcategories of "Metabolism"

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Found 8597 products of "Metabolism"

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  • LTA4H-IN-3

    CAS:
    <p>LTA4H-IN-3 (compound 9) functions as an inhibitor of LTA4H, demonstrating an IC50 of 28 nM [1].</p>
    Formula:C17H15ClN4O3
    Color and Shape:Solid
    Molecular weight:358.78
  • UGT1A1-IN-1

    CAS:
    <p>UGT1A1-IN-1 (compound 2) acts as a non-competitive inhibitor of UGT1A1, effectively inhibiting the 1-O-glucuronidation process mediated by UGT1A1 with a Ki value of 5.02 μM. This compound binds to the same ligand-binding site on UGT1A1 as bilirubin and additionally functions as a 'turn-on' fluorescent probe substrate for UGT1A1 [1].</p>
    Formula:C22H19NO3
    Color and Shape:Solid
    Molecular weight:345.39
  • DC371739

    CAS:
    <p>DC371739 is an effective oral PCSK9 inhibitor that decreases both PCSK9 and ANGPTL3 mRNA expression. It also reduces PCSK9 protein expression while enhancing that of LDLR. Given its properties, DC371739 has potential applications in the study of hyperlipidemia.</p>
    Formula:C29H30N2O4
    Color and Shape:Solid
    Molecular weight:470.56
  • E234G HYPE-IN-1

    CAS:
    <p>Compound I2.10 (E234G HYPE-IN-1) functions as an AMPylase inhibitor and exhibits low cytotoxicity toward human cell lines [1].</p>
    Formula:C14H9N5O2
    Color and Shape:Solid
    Molecular weight:279.25
  • Casein kinase 1δ-IN-25

    CAS:
    <p>Casein kinase1δ-IN-25 (compound 487) is a potent inhibitor of casein kinase1δ. It is applicable in research on neurodegenerative diseases such as Alzheimer's disease.</p>
    Formula:C20H14FN3O4S2
    Color and Shape:Solid
    Molecular weight:443.471
  • LASSBio-1632


    <p>LASSBio-1632: Novel anti-asthmatic, blocks PDE4A/D, reduces AHR &amp; lung TNF-α, crosses BBB.</p>
    Formula:C18H20N2O6S
    Color and Shape:Solid
    Molecular weight:392.43
  • 13(R)-HODE

    CAS:
    <p>13(R)-HODE, produced from linoleic acid, inhibits platelet aggregation (IC50=2.7μM) and is found in bovine endothelial cells.</p>
    Formula:C18H32O3
    Color and Shape:Solid
    Molecular weight:296.44
  • PDHK-IN-4


    <p>PDHK-IN-4 inhibits PDHK2 (IC50: 0.0051 μM) &amp; PDHK4 (IC50: 0.0122 μM), with potential for cancer research.</p>
    Formula:C24H25N5O3
    Color and Shape:Solid
    Molecular weight:431.49
  • CYP2C9/CYP2C19-IN-1


    <p>CYP2C9/CYP2C19-IN-1 is a potent inhibitor of CYP2C9/CYP2C19 without liver toxicity or genotoxicity and can be used to study Zika virus (ZIKV) infection.</p>
    Formula:C27H28N2O6S
    Color and Shape:Solid
    Molecular weight:508.59
  • RORγt inhibitor 2

    CAS:
    <p>RORγt Inhibitor 2, a potent inhibitor of RORγt, exhibits an IC50 of 9.2 nM and is utilized in the study of cancer, inflammation, or autoimmune diseases that are</p>
    Formula:C31H33F5N2O7S
    Color and Shape:Solid
    Molecular weight:672.66
  • Alkannin

    CAS:
    <p>Alkannin: potent, tumor-specific PKM2 inhibitor; non-inhibitory to PKM1/PKL; potential anticancer agent.</p>
    Formula:C16H16O5
    Color and Shape:Solid
    Molecular weight:288.3
  • PKR-IN-1

    CAS:
    <p>PKR-IN-1 (Compound 5s) is a pyruvate kinase (PK) inhibitor with antifungal properties, exhibiting an EC50 of 0.21 μg/mL against Rhizoctonia solani (R. solani).</p>
    Formula:C9HCl5N4OS2
    Color and Shape:Solid
    Molecular weight:422.525
  • Lp-PLA2-IN-5

    CAS:
    <p>Lp-PLA2-IN-5 inhibits Lp-PLA2 and PAF-AH, potentially useful in Alzheimer's and atherosclerosis studies.</p>
    Formula:C23H18F5N3O4
    Color and Shape:Solid
    Molecular weight:495.4
  • hCA XII/II/IX-IN-1


    <p>hCA XII/II/IX-IN-1 inhibits hCA I/II/IX/XII (IC50: 2.6, 0.004, 0.005, 0.001 μM) with anticancer properties.</p>
    Formula:C25H34N4O7S
    Color and Shape:Solid
    Molecular weight:534.63
  • 7-APB hydrochloride

    CAS:
    <p>7-APB hydrochloride is a benzofuran compound and serves as a metabolite of 7-MAPB.</p>
    Formula:C11H14ClNO
    Color and Shape:Solid
    Molecular weight:211.688
  • Aleglitazar

    CAS:
    <p>Aleglitazar (R1439) (R1439) is a potent dual PPARα/γ agonist, with IC50s of 38 nM and 19 nM for human PPARa and PPARγ, respectively.</p>
    Formula:C24H23NO5S
    Purity:99.03%
    Color and Shape:Solid
    Molecular weight:437.51
  • MAO-B-IN-17

    CAS:
    <p>MAO-B-IN-17 is a selective and potent monoamine oxidase B (MAO-B) inhibitor (IC50: 5.08 μM) for the study of central nervous system disorders like Parkinson's.</p>
    Formula:C17H17F2NO2
    Purity:99.41%
    Color and Shape:Soild
    Molecular weight:305.32
  • CP-642931

    CAS:
    <p>CP-642931 (Sorbitol dehydrogenase-IN-1) is a sorbitol dehydrogenase inhibitor used in the study of diabetes mellitus and cardiovascular disease.</p>
    Formula:C17H25N7O
    Purity:99.67% - >99.99%
    Color and Shape:Solid
    Molecular weight:343.43
  • BAY-3827

    CAS:
    <p>BAY-3827 is an AMPK inhibitor with antiproliferative activity and antitumor activity. BAY-3827 inhibits the phosphorylation of acetyl CoA carboxylase 1.</p>
    Formula:C27H25FN6O
    Purity:99.90%
    Color and Shape:Solid
    Molecular weight:468.53
  • Lapaquistat acetate

    CAS:
    <p>Lapaquistat acetate (TAK-475) is a squalene synthase inhibitor that reduces the cytotoxicity induced by statins in human skeletal muscle cells.</p>
    Formula:C33H41ClN2O9
    Purity:99.38% - 99.94%
    Color and Shape:Solid
    Molecular weight:645.14