Metabolism
Metabolism inhibitors are compounds that interfere with metabolic pathways, altering the production and utilization of energy within cells. These inhibitors are used to study the regulation of metabolism, the role of metabolic pathways in diseases like cancer and diabetes, and to develop new therapeutic strategies. Metabolism inhibitors can target various enzymes and processes involved in glycolysis, fatty acid oxidation, and other metabolic functions. At CymitQuimica, we offer a wide range of high-quality metabolism inhibitors to support your research in biochemistry, metabolic disorders, and drug development.
Subcategories of "Metabolism"
- AhR(42 products)
- Aminopeptidase(76 products)
- CETP(20 products)
- Carbonic Anhydrase(196 products)
- Casein Kinase(139 products)
- DHFR(30 products)
- Decarboxylase(4 products)
- Dehydrogenase(302 products)
- FAAH(64 products)
- FXR(62 products)
- Factor Xa(87 products)
- Fatty Acid Synthase(37 products)
- Ferroptosis(227 products)
- GR(3 products)
- GSNOR(3 products)
- Glucokinase(56 products)
- HIF/HIF Prolyl-Hydroxylase(146 products)
- HMG-CoA Reductase(34 products)
- Hydroxylase(36 products)
- IDO(84 products)
- LDL(7 products)
- Lipase(107 products)
- Lipid(62 products)
- Lipoxygenase(133 products)
- MAO(85 products)
- MPO(2 products)
- NAMPT(40 products)
- P450(6 products)
- PAI-1(26 products)
- PDE(170 products)
- PED(1 products)
- PKM(17 products)
- PPAR(170 products)
- Phospholipase(85 products)
- ROR(47 products)
- Retinoid Receptor(18 products)
- SGK(10 products)
- Thioredoxin(12 products)
- Transferase(30 products)
- Transporter(43 products)
- UGT(4 products)
- Xanthine Oxidase (XO) Inhibitors(9 products)
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Found 9195 products of "Metabolism"
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LRAT-IN-1
CAS:LRAT-IN-1 (compound 1) is an inhibitor of lecithin retinol acyltransferase (LRAT) with an IC50 value of 21.1 μM. This compound works by inhibiting the esterification of retinol to form retinyl esters, thereby increasing the availability of retinol in the skin to deliver anti-aging benefits. LRAT-IN-1 is under investigation for its potential use as an anti-aging ingredient in cosmetics.Formula:C27H47N5O5S2Color and Shape:SolidMolecular weight:585.82Phospho-L-arginine
CAS:Phospho-L-arginine is a derivative of arginine.Formula:C6H15N4O5PMolecular weight:254.18AZ-PFKFB3-67 quarterhydrate
AZ-PFKFB3-67 quarterhydrate inhibits PFKFB3 (IC50: 11 nM), PFKFB2 (159 nM), and PFKFB1 (1130 nM).Formula:C26H27N5O4Color and Shape:SolidMolecular weight:460.01(R)-2-formamido-4-methylpentanoic acid
CAS:(R)-2-formamido-4-methylpentanoic acid is a derivative of leucine.Formula:C7H13NO3Color and Shape:SolidMolecular weight:159.18Mitochondrial-IN-1
CAS:Mitochondrial-IN (C458) is a potent inhibitor of mitochondrial complex I. It offers significant protection against Aβ toxicity, exhibits favorable pharmacokinetic properties, and has minimal off-target effects.Formula:C22H30N2OColor and Shape:SolidMolecular weight:338.49IDH1 Inhibitor 1
CAS:Oral, brain-penetrant mutant IDH1 inhibitor targeting R132H/C with IC50: 0.021/0.045μM; 2.52μM for IDH1WT.Formula:C20H18F4N6O2Purity:98%Color and Shape:SolidMolecular weight:450.39ASB14780
ASB14780 is a 4-phenoxy derivative and an inhibitor of cytoplasmic phospholipase cPLA2α (IC50: 20 nM).Color and Shape:SolidGT-02216
CAS:GT-02216 is capable of binding allosterically to GCase, thereby enhancing its function. In primary human fibroblasts, it increases GCase activity and decreases Tau accumulation in mutant GBA1 fibroblasts. Additionally, GT-02216 offers protection to hippocampal primary neurons exposed to Tau oligomer in a rat model.Formula:C22H23N5O2Color and Shape:SolidMolecular weight:389.45LDHA-IN-5
CAS:LDHA-IN-5 is a novel and potent inhibitor targeting both glycolate oxidase (GO) and lactate dehydrogenase A (LDHA), designed for the treatment of primaryFormula:C27H22FN7O6S3Color and Shape:SolidMolecular weight:655.7JA2
CAS:JA2 is an inhibitor of metalloendopeptidase 24.15 that enhances the hypotensive response to bradykinin in rats.Formula:C33H38N4O8Color and Shape:SolidMolecular weight:618.68Carbonic anhydrase inhibitor 5
Potent hCA inhibitor: targets hCA II, IX & XII with IC50s of 42.9, 47.6, & 6.7 nM respectively.Formula:C24H20ClN3O3SColor and Shape:SolidMolecular weight:465.956-trans-12-epi-Leukotriene B4
CAS:6-trans-12-epi-Leukotriene B4, a metabolite of arachidonic acid, serves as a potent anti-inflammatory agent.Formula:C20H32O4Color and Shape:SolidMolecular weight:336.47HIF-1α-IN-5
HIF-1α-IN-5 is an inhibitor of HIF-1α with an IC 50 value of 24 nM in HEK293T cells that also inhibits the activity of MAO-A.Formula:C16H15N3O2Color and Shape:SolidMolecular weight:281.31FXIa-IN-6
CAS:FXIa-IN-6: Potent, selective FXIa inhibitor (Ki=0.3 nM); strong PK with high oral bioavailability, low clearance preclinically.Formula:C31H29ClF2N4O4Color and Shape:SolidMolecular weight:595.04IDO antagonist-1
CAS:IDO antagonist-1 (compound 163), an IDO antagonist, effectively inhibits the growth of pancreatic adenocarcinoma cells in C57BL/6 mice [1].Formula:C39H53N7O5Color and Shape:SolidMolecular weight:699.88MCTR3
CAS:MCTR3, derived from DHA via maresin 1 in macrophages, hastens tissue healing and reduces inflammation and eicosanoids post-E. coli infection in mice.Formula:C25H37NO5SColor and Shape:SolidMolecular weight:463.63FTI-2148
CAS:FTI-2148 blocks RAS-related FT-1 & GGT-1; IC50: 1.4 nM & 1.7 μM.Formula:C24H28N4O3SPurity:98%Color and Shape:SolidMolecular weight:452.57RBM14C12
CAS:RBM14C12 is a compound known for its cell signaling activity. It plays a crucial role in researching lipid metabolism and cell membrane structure. Additionally, RBM14C12 can be utilized in the development of novel compounds aimed at modulating the biological mechanisms associated with lipid-related diseases.Formula:C26H39NO6Color and Shape:SolidMolecular weight:461.59Miaosporone A
Miaosporone A: angucyclic quinone, cytotoxic to MCF-7, NCI-H187, Vero cells; anti-TB and anti-malaria with IC50 of 2.4 μM, 2.5 μM.Formula:C19H18O5Color and Shape:SolidMolecular weight:326.343'-Hydroxy Repaglinide
CAS:'3'-Hydroxy Repaglinide, a CYP2C8 metabolite of Repaglinide, treats type II diabetes.Formula:C27H36N2O5Purity:98%Color and Shape:SolidMolecular weight:468.59
