Metabolism
Metabolism inhibitors are compounds that interfere with metabolic pathways, altering the production and utilization of energy within cells. These inhibitors are used to study the regulation of metabolism, the role of metabolic pathways in diseases like cancer and diabetes, and to develop new therapeutic strategies. Metabolism inhibitors can target various enzymes and processes involved in glycolysis, fatty acid oxidation, and other metabolic functions. At CymitQuimica, we offer a wide range of high-quality metabolism inhibitors to support your research in biochemistry, metabolic disorders, and drug development.
Subcategories of "Metabolism"
- AhR(42 products)
- Aminopeptidase(76 products)
- CETP(20 products)
- Carbonic Anhydrase(196 products)
- Casein Kinase(138 products)
- DHFR(32 products)
- Decarboxylase(4 products)
- Dehydrogenase(302 products)
- FAAH(64 products)
- FXR(62 products)
- Factor Xa(85 products)
- Fatty Acid Synthase(37 products)
- Ferroptosis(226 products)
- GR(3 products)
- GSNOR(3 products)
- Glucokinase(57 products)
- HIF/HIF Prolyl-Hydroxylase(146 products)
- HMG-CoA Reductase(34 products)
- Hydroxylase(36 products)
- IDO(84 products)
- LDL(7 products)
- Lipase(107 products)
- Lipid(61 products)
- Lipoxygenase(134 products)
- MAO(87 products)
- MPO(2 products)
- NAMPT(40 products)
- P450(6 products)
- PAI-1(26 products)
- PDE(169 products)
- PED(1 products)
- PKM(17 products)
- PPAR(170 products)
- Phospholipase(86 products)
- ROR(47 products)
- Retinoid Receptor(21 products)
- SGK(10 products)
- Thioredoxin(12 products)
- Transferase(29 products)
- Transporter(44 products)
- UGT(4 products)
- Xanthine Oxidase (XO) Inhibitors(9 products)
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Found 9166 products of "Metabolism"
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LTA4H-IN-3
CAS:LTA4H-IN-3 (compound 9) functions as an inhibitor of LTA4H, demonstrating an IC50 of 28 nM [1].Formula:C17H15ClN4O3Color and Shape:SolidMolecular weight:358.78Thioquinapiperifil dihydrochloride
CAS:Thioquinapiperifil dihydrochloride is a potent, selective PDE-5 inhibitor (IC50: 0.074 nM) for research.Formula:C24H29ClN6OSPurity:99.81%Color and Shape:SolidMolecular weight:485.05Ref: TM-T9773
1mg58.00€5mg130.00€10mg187.00€25mg304.00€50mg393.00€100mg552.00€200mg725.00€1mL*10mM (DMSO)148.00€IDO antagonist-1
CAS:IDO antagonist-1 (compound 163), an IDO antagonist, effectively inhibits the growth of pancreatic adenocarcinoma cells in C57BL/6 mice [1].Formula:C39H53N7O5Color and Shape:SolidMolecular weight:699.88Lecufexor
CAS:Lecufexor is an agonist of the farnesoid X receptor (FXR).Formula:C32H21Cl3N2O5Color and Shape:SolidMolecular weight:619.88UGT1A1-IN-1
CAS:UGT1A1-IN-1 (compound 2) acts as a non-competitive inhibitor of UGT1A1, effectively inhibiting the 1-O-glucuronidation process mediated by UGT1A1 with a Ki value of 5.02 μM. This compound binds to the same ligand-binding site on UGT1A1 as bilirubin and additionally functions as a 'turn-on' fluorescent probe substrate for UGT1A1 [1].Formula:C22H19NO3Color and Shape:SolidMolecular weight:345.39Inosine 5′-diphosphate sodium
CAS:Inosine 5'-diphosphate sodium, a purine ribonucleoside diphosphate with inosine as its nucleobase, plays a role in intracellular energy metabolism and signal transduction processes.Formula:C10H13N4Na3O12P2Color and Shape:SolidMolecular weight:512.15EC33
CAS:EC33, a selective aminopeptidase A (APA) inhibitor, blocks the pressor response of exogenous Ang II and does not cross the blood-brain barrier, making it a potential candidate for salt-dependent hypertension research [1].Formula:C4H11NO3S2Color and Shape:SolidMolecular weight:185.27MAGL-IN-15
CAS:MAGL-IN-15 (Compound 6), a MAGL inhibitor, holds potential for research into diseases and disorders associated with the regulation of endocannabinoid system signaling activities [1].Formula:C16H16F6N4O3Color and Shape:SolidMolecular weight:426.31ABHD antagonist 1
CAS:ABHD antagonist 1 is an inhibitor of ABHD6 (α/β-Hydrolase domain containing 6), involved in modulating biochemical pathways affected by ABHD6, thereby influencing cell function and inflammatory responses. This compound is applicable for research in fields such as pain, neurological disorders, inflammatory diseases, autoimmune diseases, metabolic disorders, and cancer.Formula:C19H20BrN3O3SColor and Shape:SolidMolecular weight:450.35Nampt activator-4
CAS:Nampt activator-4, a positive allosteric modulator (N-PAM) of nicotinamide phosphoribosyltransferase (NAMPT), has an EC50 of 0.058 μM and can enhance nicotinamide adenine dinucleotide (NAD+) levels in cells [1].Formula:C26H22F3N7OSColor and Shape:SolidMolecular weight:537.56O-Desmethyl Brinzolamide hydrochloride
CAS:O-Desmethyl Brinzolamide hydrochloride (compound 6a), a potent metabolite derived from Brinzolamide, serves as a carbonic anhydrase (CA) inhibitor. It exhibits a dissociation constant (Kd) of 0.136 nM for CA II and an inhibitory concentration (IC50) of 165 nM for CA IV [1].Formula:C11H20ClN3O5S3Color and Shape:SolidMolecular weight:405.94Fmoc-NH-PEG6-alcohol
CAS:Fmoc-NH-PEG6-alcohol, a cleavable ADC linker, is employed in the synthesis of antibody-drug conjugates (ADCs) [1].Formula:C27H37NO8Color and Shape:SolidMolecular weight:503.58Lapaquistat
CAS:Lapaquistat: active TAK-475 metabolite; reduces cholesterol synthesis and statin myotoxicity.Formula:C31H39ClN2O8Purity:98%Color and Shape:SolidMolecular weight:603.1E234G HYPE-IN-1
CAS:Compound I2.10 (E234G HYPE-IN-1) functions as an AMPylase inhibitor and exhibits low cytotoxicity toward human cell lines [1].Formula:C14H9N5O2Color and Shape:SolidMolecular weight:279.25D-Citrulline
CAS:D-Citrulline (H-D-Cit-OH), a stereoisomer of L-citrulline, effectively reduces cardiac contractile dysfunction caused by polymorphonuclear leukocyte (PMN) in isolated perfused rat hearts undergoing ischemia/reperfusion. This protective effect is mediated through a non-NO-mediated mechanism.Formula:C6H13N3O3Color and Shape:SolidMolecular weight:175.19Sulclamide
CAS:Sulclamide, a sulfamoylbenzoic acid derivative, exhibits diuretic activity and functions as an inhibitor of carbonic anhydrase [1].Formula:C7H7ClN2O3SColor and Shape:SolidMolecular weight:234.66DDO-3733
CAS:DDO-3733 is a conformational activator of Protein Phosphatase 5 (PP5) that functions independently of TRP, facilitating the dephosphorylation of downstream substrates.Formula:C10H6F2N2OSColor and Shape:SolidMolecular weight:240.23HSD17B13-IN-19
CAS:HSD17B13-IN-19 (compound 16) acts as a potent inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), exhibiting IC50 values under 0.1 μM and under 1 μM when using estradiol and Leukotriene B3 as substrates, respectively. This compound is crucial in the treatment of nonalcoholic fatty liver diseases (NAFLDs), such as nonalcoholic steatohepatitis (NASH) [1].Formula:C23H23FN2O4SColor and Shape:SolidMolecular weight:442.5Homodestcardin
CAS:Homodestcardin: cyclic depsipeptide from T. roseum with immunosuppressant properties; inhibits mouse T cell proliferation.Formula:C32H55N5O7Color and Shape:SolidMolecular weight:621.81Carbonic anhydrase inhibitor 8
R-13, a carbonic anhydrase inhibitor, has Ki of 60.7 nM (hCA I), 320.7 nM (hCA II), and 2298 nM (hCA IV).Formula:C20H25N3O4SColor and Shape:SolidMolecular weight:403.5
