
Metabolism
Metabolism inhibitors are compounds that interfere with metabolic pathways, altering the production and utilization of energy within cells. These inhibitors are used to study the regulation of metabolism, the role of metabolic pathways in diseases like cancer and diabetes, and to develop new therapeutic strategies. Metabolism inhibitors can target various enzymes and processes involved in glycolysis, fatty acid oxidation, and other metabolic functions. At CymitQuimica, we offer a wide range of high-quality metabolism inhibitors to support your research in biochemistry, metabolic disorders, and drug development.
Subcategories of "Metabolism"
- AhR(41 products)
- Aminopeptidase(67 products)
- CETP(18 products)
- Carbonic Anhydrase(178 products)
- Casein Kinase(130 products)
- DHFR(33 products)
- Decarboxylase(4 products)
- Dehydrogenase(269 products)
- FAAH(64 products)
- FXR(58 products)
- Factor Xa(80 products)
- Fatty Acid Synthase(32 products)
- Ferroptosis(215 products)
- GR(3 products)
- GSNOR(3 products)
- Glucokinase(54 products)
- HIF/HIF Prolyl-Hydroxylase(142 products)
- HMG-CoA Reductase(33 products)
- Hydroxylase(30 products)
- IDO(82 products)
- LDL(8 products)
- Lipase(97 products)
- Lipid(59 products)
- Lipoxygenase(124 products)
- MAO(87 products)
- MPO(2 products)
- NAMPT(36 products)
- P450(6 products)
- PAI-1(25 products)
- PDE(166 products)
- PED(1 products)
- PKM(15 products)
- PPAR(164 products)
- Phospholipase(82 products)
- ROR(42 products)
- Retinoid Receptor(29 products)
- SGK(11 products)
- Thioredoxin(12 products)
- Transferase(30 products)
- Transporter(42 products)
- UGT(4 products)
- Xanthine Oxidase (XO) Inhibitors(9 products)
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Found 8626 products of "Metabolism"
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N-Oleoyl Taurine
CAS:<p>N-Oleoyl taurine, an amino-acyl endocannabinoid isolated from rat brain, along with several arachidonoyl amino acids such as N-arachidonoyl dopamine and N-arachidonoyl serine, have been derived from bovine brain. Mass spectral lipidomics analysis of rat brain revealed a series of fatty acyl amides of taurine, marking the discovery of a new class of compounds. These compounds, found in the kidney, are known to activate members of the transient receptor potential (TRP) family of calcium channels, with N-Oleoyl taurine specifically potentially activating TRPV1 and TRPV4 channels.</p>Formula:C20H39NO4SColor and Shape:SolidMolecular weight:389.61,2-Dilauroyl-sn-glycero-3-phospho-(2R)-glycerol sodium
CAS:<p>1,2-Dilauroyl-sn-glycero-3-phospho-(2R)-glycerol is a type of phosphoglycerol characterized by the presence of lauric acid at the sn-1 and sn-2 positions. [Matreya, LLC. Catalog No. 1443]</p>Formula:C30H58O10PNaColor and Shape:SolidMolecular weight:632.74Kelatorphan
CAS:<p>Kelatorphan is an enkephalin degrading enzyme full inhibitor.</p>Formula:C14H18N2O5Purity:98%Color and Shape:SolidMolecular weight:294.3GSK-8062
CAS:<p>GSK-8062 is an agonist of farnesoid X receptor (FXR).</p>Formula:C30H23Cl2NO4Purity:98%Color and Shape:SolidMolecular weight:532.41Imiglitazar
CAS:<p>Imiglitazar (TAK559) is a potent PPAR-β/δ receptor agonist with hypoglycemic effects.</p>Formula:C28H26N2O5Purity:97.33%Color and Shape:SolidMolecular weight:470.52SHP394
CAS:<p>SHP394 is an orally efficacious inhibitor of protein tyrosine phosphatase SHP2 (IC50: 23 nM).</p>Formula:C20H25F3N6O2SPurity:98%Color and Shape:SolidMolecular weight:470.511,3-Dipalmitoyl glycero-2-PE
CAS:<p>1,3-Dipalmitoyl glycero-2-phosphatidylethanolamine is a phospholipid incorporating saturated long-chain (16:0) stearic acid at the sn-1 and sn-3 positions, with phosphatidylethanolamine (PE) at the sn-2 position. Phosphatidylethanolamines, critical components of biological membranes, play essential structural and functional roles. Various PE types are instrumental in forming micelles, liposomes, and other synthetic membranes.</p>Formula:C37H74NO8PColor and Shape:SolidMolecular weight:691.9721-Palmitoyl-2-Oleoyl-sn-glycero-3-PA
CAS:<p>1-Palmitoyl-2-oleoyl-sn-glycero-3-PA (1,2-POPA) is a phospholipid featuring a palmitic acid (16:0) chain that is saturated and an oleic acid (18:1) chain that is monounsaturated, positioned at the sn-1 and sn-2 locations, respectively. This compound is utilized in creating micelles, liposomes, and various artificial membrane forms.</p>Formula:C37H71O8PColor and Shape:SolidMolecular weight:674.9VU0364739
CAS:<p>VU0364739, a selective phospholipase D2 (PLD2) inhibitor with an IC50 of 22 nM, effectively reduces cancer cell proliferation [1].</p>Formula:C26H27FN4O2Purity:98%Color and Shape:SolidMolecular weight:446.52sEH/AChE-IN-3
CAS:<p>sEH/AChE-IN-3 -15: potent dual sEH & AChE inhibitor; crosses BBB; IC50: hsEH 0.4nM, hAChE 1.94nM, hBChE 615nM, msEH 4.3nM, mAChE 2.61nM.</p>Formula:C35H39ClF3N5O3Color and Shape:SolidMolecular weight:670.16FAS-IN-1 Tosylate
<p>FAS-IN-1 Tosylate is an effective fatty acid synthase inhibitor;Has an IC50 of 10 nM.</p>Formula:C33H35N3O7S2Purity:98%Color and Shape:SolidMolecular weight:649.78Iomazenil
CAS:<p>Iomazenil is an antagonist and partial inverse agonist of benzodiazepine and potential therapy for alcohol abuse.</p>Formula:C15H14IN3O3Purity:98%Color and Shape:SolidMolecular weight:411.19MMV009085
CAS:<p>MMV009085 is a potent inhibitor of the Plasmodium falciparum hexose transporter (Pf HT1), with potential as an anti-malarial agent.</p>Formula:C22H22N2O6Color and Shape:SolidMolecular weight:410.42PDE5-IN-42
CAS:<p>PDE5-IN-42 is a selective inhibitor of second-generation phosphodiesterase type 5 (PDE5).</p>Formula:C23H31N7O3Purity:98%Color and Shape:SolidMolecular weight:453.54JTV-803 mesylate
CAS:<p>JTV-803 inhibits factor Xa (K(i) 0.019 µM, IC(50) 0.081 µM), 100x more selective vs thrombin, extends clotting times dose-dependently.</p>Formula:C23H31N5O6SPurity:98%Color and Shape:SolidMolecular weight:505.59S-Fcme
CAS:<p>S-Fcme activates multidrug resistance transporter by boosting ATPase activity and competing for drug binding.</p>Formula:C19H33NO2SColor and Shape:SolidMolecular weight:339.54GSK2973980A
CAS:<p>GSK2973980A is a selective Acyl-CoA:diacylglycerol acyltransferase 1 (DGAT1) inhibitor (IC50: 3 nM).</p>Formula:C25H19F5N4O4Purity:98%Color and Shape:SolidMolecular weight:534.43KD-026
CAS:<p>KD-026 (SLx 4090), a microsomal triglyceride transfer protein (MTP) inhibitor(IC50 = 8.0 nM), is used in type 2 diabetes studies.</p>Formula:C31H25F3N2O4Purity:99.74%Color and Shape:SolidMolecular weight:546.54Cholesterol 24-hydroxylase-IN-2
CAS:<p>Cholesterol 24-hydroxylase-IN-2 is a potent inhibitor of cholesterol 24-hydroxylase (CH24H or CYP46A1), exhibiting an IC50 value of 5.4 nM, and has potential</p>Formula:C20H23FN4OColor and Shape:SolidMolecular weight:354.424-Methylumbelliferyl-α-D-Glucopyranoside
CAS:<p>4-Methylumbelliferyl-α-D-Glucopyranoside (4MU-αGlc) is a fluorescence substrate for α-glucosidase, serving as a biomarker for Fabry disease and Pompe disease</p>Formula:C16H18O8Purity:99.97%Color and Shape:SolidMolecular weight:338.31FXIa-IN-1
CAS:<p>FXIa-IN-1 is a potent β-lactam covalent heparin-derived factor XIa (fXIa) inhibitor.</p>Formula:C20H19F3N4O5Purity:98%Color and Shape:SolidMolecular weight:452.38CoPoP
CAS:<p>CoPoP, a liposome-based vaccine adjuvant, holds potential for application in cancer research [1].</p>Formula:C57H80CoN5O9PColor and Shape:SolidMolecular weight:1069.18VU0155069 hydrochloride
CAS:<p>VU0155069 hydrochloride (CAY10593 hydrochloride) is a potent and selective inhibitor of phospholipase D (PLD), exhibiting IC50 values of 46 nM for PLD1 and 933 nM for PLD2. It effectively inhibits the migration of both human and mouse breast cancer cell lines [1] [2].</p>Formula:C26H28Cl2N4O2Color and Shape:SolidMolecular weight:499.43A 62198
CAS:<p>A 62198 is a potent and selective renin inhibitor with potential as a hypotensive agent.</p>Formula:C30H44N8O5Purity:98%Color and Shape:SolidMolecular weight:596.72ICMT-IN-33
CAS:<p>ICMT-IN-33 (compound 73) functions as an ICMT inhibitor with an IC50 value of 0.46 μM [1].</p>Formula:C20H24ClNOColor and Shape:SolidMolecular weight:329.86Quetiapine sulfoxide dihydrochloride
CAS:<p>Quetiapine sulfoxide dihydrochloride, a major metabolite of second-gen antipsychotic Quetiapine, modulates 5-HT and dopamine receptors.</p>Formula:C21H27Cl2N3O3SPurity:98%Color and Shape:SolidMolecular weight:472.43ICMT-IN-26
CAS:<p>ICMT-IN-26 (compound 38) acts as an ICMT inhibitor with an IC50 value of 0.36 μM [1].</p>Formula:C21H26ClNOColor and Shape:SolidMolecular weight:343.89Glucocerebrosidase-IN-1 hydrochloride
CAS:<p>Glucocerebrosidase-IN-1 (compound 11a) hydrochloride is a potent, selective GCase (glucocerebrosidase) inhibitor with IC50 and Ki values of 29.3 μM and 18.5 μM</p>Formula:C13H28ClNO3Purity:98%Color and Shape:SolidMolecular weight:281.82FM26
CAS:FM26, an isoxazole-based RORγt inverse agonist, cuts EL4 IL-17a mRNA; potent with 264 nM IC50.Formula:C22H15ClF3N3O3Purity:98%Color and Shape:SolidMolecular weight:461.82GNE-6468
CAS:<p>GNE-6468 is a potent and selective agonist of RORγ(RORc) (EC50: 13 nM for HEK-293 cell).</p>Formula:C23H16ClN3O4Color and Shape:SolidMolecular weight:433.8412(R)-HEPE
CAS:<p>12(R)-HEPE, a monohydroxy fatty acid derived from EPA in the eggs of the sea urchin S. purpuratus, has a biological activity that, while not extensively documented, may resemble that of 12(R)-HETE (Catalog No.34560).</p>Formula:C20H30O3Color and Shape:SolidMolecular weight:318.5CM-10-18
CAS:<p>CM-10-18: potent ER α-glucosidase inhibitor, strong antiviral against hemorrhagic fever viruses, protects mice from dengue fatality.</p>Formula:C17H35NO5Color and Shape:SolidMolecular weight:333.4611-dehydro Thromboxane B3
CAS:<p>11-Dehydro Thromboxane B3 (11-dehydro TXB3) serves as a urinary metabolite of TXA3 in humans following an increased dietary intake of EPA.</p>Formula:C20H30O6Color and Shape:SolidMolecular weight:366.53,5-Dinitrocatechol
CAS:<p>OR-486 is an inhibitor of catechol-O-methyl-transferase(COMT) and can be used to prepare the molybdenum (VI)- 3,5-Dinitrocatechol complex.</p>Formula:C6H4N2O6Purity:99.8%Color and Shape:SolidMolecular weight:200.11R1498
CAS:<p>R1498 inhibits CDK2, targets angiogenesis and mitosis, and is an oral treatment for liver and stomach cancer.</p>Formula:C18H15ClN4OPurity:98%Color and Shape:SolidMolecular weight:338.79GSK321
CAS:<p>GSK321 is an IDH1 inhibitor that prevents cytoplasmic glutamine reductive carboxylation.GSK321 is used in the study of leukemia.</p>Formula:C28H28FN5O3Purity:99.73%Color and Shape:SolidMolecular weight:501.55Dendrogenin A
CAS:<p>Dendrogenin A (DDA) is a compound acting as a selective liver X receptor (LXR) modulator, cholesterol epoxide hydrolase inhibitor (Ki = 120 nM), and a metabolic</p>Formula:C32H55N3O2Color and Shape:SolidMolecular weight:513.80Glycosidase-IN-1
CAS:<p>Glycosidase-IN-1, a D-mannose-derived inhibitor, has hypoglycemic effects and aids in creating immunosuppressants and β-glucosidase blockers.</p>Formula:C13H23NO5Purity:98%Color and Shape:SolidMolecular weight:273.33FR-186054
CAS:<p>FR-186054, a potent ACAT inhibitor with high oral efficacy, outperforms others in vitro regardless of dosage.</p>Formula:C26H27N5OS2Purity:98%Color and Shape:SolidMolecular weight:489.66FXR antagonist 1
CAS:<p>"Oral FXR antagonist 1 selectively blocks intestinal FXR, with IC50 of 2.1 μM, aiding in NASH research by improving liver health."</p>Formula:C36H59NO5Color and Shape:SolidMolecular weight:585.86SHP2-IN-19
CAS:<p>SHP2-IN-19 (compound 183) is a SHP2 inhibitor exhibiting potent activity with an IC50 of 3 nM, and is utilized in glioblastoma research [1].</p>Formula:C27H28N6O2Color and Shape:SolidMolecular weight:468.55N-type calcium channel blocker-1
CAS:<p>N-type calcium channel blocker-1 is an orally active analgesic agent,shows high affinity to functionally block N-type calcium channels.</p>Formula:C31H47N3Purity:98%Color and Shape:SolidMolecular weight:461.73Difamilast
CAS:<p>Difamilast is a selective inhibitor of phosphodiesterase-4 (PDE4) with particularly efficient inhibition of subtype B (IC50=11.2 nM).</p>Formula:C23H24F2N2O5Purity:99.64%Color and Shape:SolidMolecular weight:446.44UK-157147
CAS:<p>UK-157147 is a substrate for UGT1A1(Km: 105 μM).</p>Formula:C23H24N2O7SPurity:98%Color and Shape:SolidMolecular weight:472.51ATX-001
CAS:<p>ATX-001, an ionizable cationic lipid, is utilized in the creation of lipid nanoparticles (LNPs) for mRNA delivery [1].</p>Formula:C40H74N2O5SColor and Shape:SolidMolecular weight:695.09Selenocystine
CAS:<p>Selenocystine, a broad-spectrum anticancer agent, effectively induces DNA damage, notably DNA double-strand breaks (DSBs), in HepG2 cells, showcasing</p>Formula:C6H12N2O4Se2Purity:98%Color and Shape:SolidMolecular weight:334.091,2-Dilinoleoyl-sn-glycero-3-PC
CAS:<p>1,2-Dilinoleoyl-sn-glycero-3-PC (Dilinoleoyllecithin), a phospholipid, finds application in the production of artificial membranes [1].</p>Formula:C44H80NO8PColor and Shape:SolidMolecular weight:782.097HSD17B13-IN-3
CAS:<p>HSD17B13-IN-3 (compound 2) is a potent inhibitor of hydroxysteroid 17ß-dehydrogenase 13 (HSD17B13), lacking cellular experimental activity [1].</p>Formula:C22H21NO6S2Color and Shape:SolidMolecular weight:459.541-Deazaadenosine
CAS:<p>1-Deazaadenosine, an adenosine deaminase inhibitor (Ki: 0.66 μM), may treat cancer, particularly lymphoproliferative disorders.</p>Formula:C11H14N4O4Purity:98%Color and Shape:SolidMolecular weight:266.25DOG-IM4
CAS:<p>DOG-IM4 is a chemical compound instrumental in synthesizing nanoparticles for delivering antigen-encoding nucleic acids, targeting a broad range of conditions including autoimmune diseases, rare blood or metabolic disorders, allergies, cancer, and infectious diseases [1].</p>Formula:C51H95N3O7Color and Shape:SolidMolecular weight:862.32
