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Metabolism

Metabolism

Metabolism inhibitors are compounds that interfere with metabolic pathways, altering the production and utilization of energy within cells. These inhibitors are used to study the regulation of metabolism, the role of metabolic pathways in diseases like cancer and diabetes, and to develop new therapeutic strategies. Metabolism inhibitors can target various enzymes and processes involved in glycolysis, fatty acid oxidation, and other metabolic functions. At CymitQuimica, we offer a wide range of high-quality metabolism inhibitors to support your research in biochemistry, metabolic disorders, and drug development.

Subcategories of "Metabolism"

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Found 8626 products of "Metabolism"

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  • N-Oleoyl Taurine

    CAS:
    <p>N-Oleoyl taurine, an amino-acyl endocannabinoid isolated from rat brain, along with several arachidonoyl amino acids such as N-arachidonoyl dopamine and N-arachidonoyl serine, have been derived from bovine brain. Mass spectral lipidomics analysis of rat brain revealed a series of fatty acyl amides of taurine, marking the discovery of a new class of compounds. These compounds, found in the kidney, are known to activate members of the transient receptor potential (TRP) family of calcium channels, with N-Oleoyl taurine specifically potentially activating TRPV1 and TRPV4 channels.</p>
    Formula:C20H39NO4S
    Color and Shape:Solid
    Molecular weight:389.6
  • 1,2-Dilauroyl-sn-glycero-3-phospho-(2R)-glycerol sodium

    CAS:
    <p>1,2-Dilauroyl-sn-glycero-3-phospho-(2R)-glycerol is a type of phosphoglycerol characterized by the presence of lauric acid at the sn-1 and sn-2 positions. [Matreya, LLC. Catalog No. 1443]</p>
    Formula:C30H58O10PNa
    Color and Shape:Solid
    Molecular weight:632.74
  • Kelatorphan

    CAS:
    <p>Kelatorphan is an enkephalin degrading enzyme full inhibitor.</p>
    Formula:C14H18N2O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:294.3
  • GSK-8062

    CAS:
    <p>GSK-8062 is an agonist of farnesoid X receptor (FXR).</p>
    Formula:C30H23Cl2NO4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:532.41
  • Imiglitazar

    CAS:
    <p>Imiglitazar (TAK559) is a potent PPAR-β/δ receptor agonist with hypoglycemic effects.</p>
    Formula:C28H26N2O5
    Purity:97.33%
    Color and Shape:Solid
    Molecular weight:470.52
  • SHP394

    CAS:
    <p>SHP394 is an orally efficacious inhibitor of protein tyrosine phosphatase SHP2 (IC50: 23 nM).</p>
    Formula:C20H25F3N6O2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:470.51
  • 1,3-Dipalmitoyl glycero-2-PE

    CAS:
    <p>1,3-Dipalmitoyl glycero-2-phosphatidylethanolamine is a phospholipid incorporating saturated long-chain (16:0) stearic acid at the sn-1 and sn-3 positions, with phosphatidylethanolamine (PE) at the sn-2 position. Phosphatidylethanolamines, critical components of biological membranes, play essential structural and functional roles. Various PE types are instrumental in forming micelles, liposomes, and other synthetic membranes.</p>
    Formula:C37H74NO8P
    Color and Shape:Solid
    Molecular weight:691.972
  • 1-Palmitoyl-2-Oleoyl-sn-glycero-3-PA

    CAS:
    <p>1-Palmitoyl-2-oleoyl-sn-glycero-3-PA (1,2-POPA) is a phospholipid featuring a palmitic acid (16:0) chain that is saturated and an oleic acid (18:1) chain that is monounsaturated, positioned at the sn-1 and sn-2 locations, respectively. This compound is utilized in creating micelles, liposomes, and various artificial membrane forms.</p>
    Formula:C37H71O8P
    Color and Shape:Solid
    Molecular weight:674.9
  • VU0364739

    CAS:
    <p>VU0364739, a selective phospholipase D2 (PLD2) inhibitor with an IC50 of 22 nM, effectively reduces cancer cell proliferation [1].</p>
    Formula:C26H27FN4O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:446.52
  • sEH/AChE-IN-3

    CAS:
    <p>sEH/AChE-IN-3 -15: potent dual sEH &amp; AChE inhibitor; crosses BBB; IC50: hsEH 0.4nM, hAChE 1.94nM, hBChE 615nM, msEH 4.3nM, mAChE 2.61nM.</p>
    Formula:C35H39ClF3N5O3
    Color and Shape:Solid
    Molecular weight:670.16
  • FAS-IN-1 Tosylate


    <p>FAS-IN-1 Tosylate is an effective fatty acid synthase inhibitor;Has an IC50 of 10 nM.</p>
    Formula:C33H35N3O7S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:649.78
  • Iomazenil

    CAS:
    <p>Iomazenil is an antagonist and partial inverse agonist of benzodiazepine and potential therapy for alcohol abuse.</p>
    Formula:C15H14IN3O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:411.19
  • MMV009085

    CAS:
    <p>MMV009085 is a potent inhibitor of the Plasmodium falciparum hexose transporter (Pf HT1), with potential as an anti-malarial agent.</p>
    Formula:C22H22N2O6
    Color and Shape:Solid
    Molecular weight:410.42
  • PDE5-IN-42

    CAS:
    <p>PDE5-IN-42 is a selective inhibitor of second-generation phosphodiesterase type 5 (PDE5).</p>
    Formula:C23H31N7O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:453.54
  • JTV-803 mesylate

    CAS:
    <p>JTV-803 inhibits factor Xa (K(i) 0.019 µM, IC(50) 0.081 µM), 100x more selective vs thrombin, extends clotting times dose-dependently.</p>
    Formula:C23H31N5O6S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:505.59
  • S-Fcme

    CAS:
    <p>S-Fcme activates multidrug resistance transporter by boosting ATPase activity and competing for drug binding.</p>
    Formula:C19H33NO2S
    Color and Shape:Solid
    Molecular weight:339.54
  • GSK2973980A

    CAS:
    <p>GSK2973980A is a selective Acyl-CoA:diacylglycerol acyltransferase 1 (DGAT1) inhibitor (IC50: 3 nM).</p>
    Formula:C25H19F5N4O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:534.43
  • KD-026

    CAS:
    <p>KD-026 (SLx 4090), a microsomal triglyceride transfer protein (MTP) inhibitor(IC50 = 8.0 nM), is used in type 2 diabetes studies.</p>
    Formula:C31H25F3N2O4
    Purity:99.74%
    Color and Shape:Solid
    Molecular weight:546.54
  • Cholesterol 24-hydroxylase-IN-2

    CAS:
    <p>Cholesterol 24-hydroxylase-IN-2 is a potent inhibitor of cholesterol 24-hydroxylase (CH24H or CYP46A1), exhibiting an IC50 value of 5.4 nM, and has potential</p>
    Formula:C20H23FN4O
    Color and Shape:Solid
    Molecular weight:354.42
  • 4-Methylumbelliferyl-α-D-Glucopyranoside

    CAS:
    <p>4-Methylumbelliferyl-α-D-Glucopyranoside (4MU-αGlc) is a fluorescence substrate for α-glucosidase, serving as a biomarker for Fabry disease and Pompe disease</p>
    Formula:C16H18O8
    Purity:99.97%
    Color and Shape:Solid
    Molecular weight:338.31
  • FXIa-IN-1

    CAS:
    <p>FXIa-IN-1 is a potent β-lactam covalent heparin-derived factor XIa (fXIa) inhibitor.</p>
    Formula:C20H19F3N4O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:452.38
  • CoPoP

    CAS:
    <p>CoPoP, a liposome-based vaccine adjuvant, holds potential for application in cancer research [1].</p>
    Formula:C57H80CoN5O9P
    Color and Shape:Solid
    Molecular weight:1069.18
  • VU0155069 hydrochloride

    CAS:
    <p>VU0155069 hydrochloride (CAY10593 hydrochloride) is a potent and selective inhibitor of phospholipase D (PLD), exhibiting IC50 values of 46 nM for PLD1 and 933 nM for PLD2. It effectively inhibits the migration of both human and mouse breast cancer cell lines [1] [2].</p>
    Formula:C26H28Cl2N4O2
    Color and Shape:Solid
    Molecular weight:499.43
  • A 62198

    CAS:
    <p>A 62198 is a potent and selective renin inhibitor with potential as a hypotensive agent.</p>
    Formula:C30H44N8O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:596.72
  • ICMT-IN-33

    CAS:
    <p>ICMT-IN-33 (compound 73) functions as an ICMT inhibitor with an IC50 value of 0.46 μM [1].</p>
    Formula:C20H24ClNO
    Color and Shape:Solid
    Molecular weight:329.86
  • Quetiapine sulfoxide dihydrochloride

    CAS:
    <p>Quetiapine sulfoxide dihydrochloride, a major metabolite of second-gen antipsychotic Quetiapine, modulates 5-HT and dopamine receptors.</p>
    Formula:C21H27Cl2N3O3S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:472.43
  • ICMT-IN-26

    CAS:
    <p>ICMT-IN-26 (compound 38) acts as an ICMT inhibitor with an IC50 value of 0.36 μM [1].</p>
    Formula:C21H26ClNO
    Color and Shape:Solid
    Molecular weight:343.89
  • Glucocerebrosidase-IN-1 hydrochloride

    CAS:
    <p>Glucocerebrosidase-IN-1 (compound 11a) hydrochloride is a potent, selective GCase (glucocerebrosidase) inhibitor with IC50 and Ki values of 29.3 μM and 18.5 μM</p>
    Formula:C13H28ClNO3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:281.82
  • FM26

    CAS:
    FM26, an isoxazole-based RORγt inverse agonist, cuts EL4 IL-17a mRNA; potent with 264 nM IC50.
    Formula:C22H15ClF3N3O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:461.82
  • GNE-6468

    CAS:
    <p>GNE-6468 is a potent and selective agonist of RORγ(RORc) (EC50: 13 nM for HEK-293 cell).</p>
    Formula:C23H16ClN3O4
    Color and Shape:Solid
    Molecular weight:433.84
  • 12(R)-HEPE

    CAS:
    <p>12(R)-HEPE, a monohydroxy fatty acid derived from EPA in the eggs of the sea urchin S. purpuratus, has a biological activity that, while not extensively documented, may resemble that of 12(R)-HETE (Catalog No.34560).</p>
    Formula:C20H30O3
    Color and Shape:Solid
    Molecular weight:318.5
  • CM-10-18

    CAS:
    <p>CM-10-18: potent ER α-glucosidase inhibitor, strong antiviral against hemorrhagic fever viruses, protects mice from dengue fatality.</p>
    Formula:C17H35NO5
    Color and Shape:Solid
    Molecular weight:333.46
  • 11-dehydro Thromboxane B3

    CAS:
    <p>11-Dehydro Thromboxane B3 (11-dehydro TXB3) serves as a urinary metabolite of TXA3 in humans following an increased dietary intake of EPA.</p>
    Formula:C20H30O6
    Color and Shape:Solid
    Molecular weight:366.5
  • 3,5-Dinitrocatechol

    CAS:
    <p>OR-486 is an inhibitor of catechol-O-methyl-transferase(COMT) and can be used to prepare the molybdenum (VI)- 3,5-Dinitrocatechol complex.</p>
    Formula:C6H4N2O6
    Purity:99.8%
    Color and Shape:Solid
    Molecular weight:200.11
  • R1498

    CAS:
    <p>R1498 inhibits CDK2, targets angiogenesis and mitosis, and is an oral treatment for liver and stomach cancer.</p>
    Formula:C18H15ClN4O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:338.79
  • GSK321

    CAS:
    <p>GSK321 is an IDH1 inhibitor that prevents cytoplasmic glutamine reductive carboxylation.GSK321 is used in the study of leukemia.</p>
    Formula:C28H28FN5O3
    Purity:99.73%
    Color and Shape:Solid
    Molecular weight:501.55
  • Dendrogenin A

    CAS:
    <p>Dendrogenin A (DDA) is a compound acting as a selective liver X receptor (LXR) modulator, cholesterol epoxide hydrolase inhibitor (Ki = 120 nM), and a metabolic</p>
    Formula:C32H55N3O2
    Color and Shape:Solid
    Molecular weight:513.80
  • Glycosidase-IN-1

    CAS:
    <p>Glycosidase-IN-1, a D-mannose-derived inhibitor, has hypoglycemic effects and aids in creating immunosuppressants and β-glucosidase blockers.</p>
    Formula:C13H23NO5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:273.33
  • FR-186054

    CAS:
    <p>FR-186054, a potent ACAT inhibitor with high oral efficacy, outperforms others in vitro regardless of dosage.</p>
    Formula:C26H27N5OS2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:489.66
  • FXR antagonist 1

    CAS:
    <p>"Oral FXR antagonist 1 selectively blocks intestinal FXR, with IC50 of 2.1 μM, aiding in NASH research by improving liver health."</p>
    Formula:C36H59NO5
    Color and Shape:Solid
    Molecular weight:585.86
  • SHP2-IN-19

    CAS:
    <p>SHP2-IN-19 (compound 183) is a SHP2 inhibitor exhibiting potent activity with an IC50 of 3 nM, and is utilized in glioblastoma research [1].</p>
    Formula:C27H28N6O2
    Color and Shape:Solid
    Molecular weight:468.55
  • N-type calcium channel blocker-1

    CAS:
    <p>N-type calcium channel blocker-1 is an orally active analgesic agent,shows high affinity to functionally block N-type calcium channels.</p>
    Formula:C31H47N3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:461.73
  • Difamilast

    CAS:
    <p>Difamilast is a selective inhibitor of phosphodiesterase-4 (PDE4) with particularly efficient inhibition of subtype B (IC50=11.2 nM).</p>
    Formula:C23H24F2N2O5
    Purity:99.64%
    Color and Shape:Solid
    Molecular weight:446.44
  • UK-157147

    CAS:
    <p>UK-157147 is a substrate for UGT1A1(Km: 105 μM).</p>
    Formula:C23H24N2O7S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:472.51
  • ATX-001

    CAS:
    <p>ATX-001, an ionizable cationic lipid, is utilized in the creation of lipid nanoparticles (LNPs) for mRNA delivery [1].</p>
    Formula:C40H74N2O5S
    Color and Shape:Solid
    Molecular weight:695.09
  • Selenocystine

    CAS:
    <p>Selenocystine, a broad-spectrum anticancer agent, effectively induces DNA damage, notably DNA double-strand breaks (DSBs), in HepG2 cells, showcasing</p>
    Formula:C6H12N2O4Se2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:334.09
  • 1,2-Dilinoleoyl-sn-glycero-3-PC

    CAS:
    <p>1,2-Dilinoleoyl-sn-glycero-3-PC (Dilinoleoyllecithin), a phospholipid, finds application in the production of artificial membranes [1].</p>
    Formula:C44H80NO8P
    Color and Shape:Solid
    Molecular weight:782.097
  • HSD17B13-IN-3

    CAS:
    <p>HSD17B13-IN-3 (compound 2) is a potent inhibitor of hydroxysteroid 17ß-dehydrogenase 13 (HSD17B13), lacking cellular experimental activity [1].</p>
    Formula:C22H21NO6S2
    Color and Shape:Solid
    Molecular weight:459.54
  • 1-Deazaadenosine

    CAS:
    <p>1-Deazaadenosine, an adenosine deaminase inhibitor (Ki: 0.66 μM), may treat cancer, particularly lymphoproliferative disorders.</p>
    Formula:C11H14N4O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:266.25
  • DOG-IM4

    CAS:
    <p>DOG-IM4 is a chemical compound instrumental in synthesizing nanoparticles for delivering antigen-encoding nucleic acids, targeting a broad range of conditions including autoimmune diseases, rare blood or metabolic disorders, allergies, cancer, and infectious diseases [1].</p>
    Formula:C51H95N3O7
    Color and Shape:Solid
    Molecular weight:862.32