Metabolism
Metabolism inhibitors are compounds that interfere with metabolic pathways, altering the production and utilization of energy within cells. These inhibitors are used to study the regulation of metabolism, the role of metabolic pathways in diseases like cancer and diabetes, and to develop new therapeutic strategies. Metabolism inhibitors can target various enzymes and processes involved in glycolysis, fatty acid oxidation, and other metabolic functions. At CymitQuimica, we offer a wide range of high-quality metabolism inhibitors to support your research in biochemistry, metabolic disorders, and drug development.
Subcategories of "Metabolism"
- AhR(41 products)
- Aminopeptidase(67 products)
- CETP(18 products)
- Carbonic Anhydrase(177 products)
- Casein Kinase(130 products)
- DHFR(32 products)
- Decarboxylase(4 products)
- Dehydrogenase(267 products)
- FAAH(63 products)
- FXR(58 products)
- Factor Xa(80 products)
- Fatty Acid Synthase(32 products)
- Ferroptosis(215 products)
- GR(3 products)
- GSNOR(3 products)
- Glucokinase(53 products)
- HIF/HIF Prolyl-Hydroxylase(142 products)
- HMG-CoA Reductase(32 products)
- Hydroxylase(30 products)
- IDO(82 products)
- LDL(8 products)
- Lipase(96 products)
- Lipid(59 products)
- Lipoxygenase(124 products)
- MAO(87 products)
- MPO(2 products)
- NAMPT(36 products)
- P450(6 products)
- PAI-1(25 products)
- PDE(165 products)
- PED(1 products)
- PKM(15 products)
- PPAR(164 products)
- Phospholipase(82 products)
- ROR(42 products)
- Retinoid Receptor(29 products)
- SGK(11 products)
- Thioredoxin(12 products)
- Transferase(30 products)
- Transporter(42 products)
- UGT(4 products)
- Xanthine Oxidase (XO) Inhibitors(9 products)
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Found 8597 products of "Metabolism"
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NADH-IN-2
CAS:<p>NADH-IN-2 (compound 8) is a Type II NADH dehydrogenase inhibitor.</p>Formula:C16H16N2Color and Shape:SolidMolecular weight:236.31Inosine 5′-diphosphate sodium
CAS:<p>Inosine 5'-diphosphate sodium, a purine ribonucleoside diphosphate with inosine as its nucleobase, plays a role in intracellular energy metabolism and signal transduction processes.</p>Formula:C10H13N4Na3O12P2Color and Shape:SolidMolecular weight:512.15Beloranib
CAS:<p>Beloranib is a fumagillin anticancer drug. Beloranib belongs to an angiogenesis inhibitor.</p>Formula:C29H41NO6Purity:98%Color and Shape:SolidMolecular weight:499.64GSK2945 hydrochloride
<p>GSK2945 HCl is a specific Rev-erbα antagonist, EC50: 21.5 μM (mouse), 20.8 μM (human), increases cholesterol 7α-hydroxylase.</p>Formula:C20H19Cl3N2O2SColor and Shape:SolidMolecular weight:457.8GSK864
CAS:<p>GSK864 is an inhibitor of isocitrate dehydrogenase 1 (IDH1) mutant. GSK864 inhibits IDH1 mutants R132C, R132H, and R132G (IC50: 8.8, 15.2, and 16.6 nM).</p>Formula:C30H31FN6O4Purity:97.07%Color and Shape:SolidMolecular weight:558.6PDHK-IN-5
<p>PDHK-IN-5, potent PDHK2 (0.006 μM IC50) & PDHK4 (0.0329 μM IC50) inhibitor, may be explored for cancer and diabetes treatment.</p>Formula:C30H31N5O2Color and Shape:SolidMolecular weight:493.67PPD-Q
CAS:<p>7PPD-Q is a substituted p-phenylenediamine antioxidant derivative. It exhibits toxicity towards the bacterium V. fischeri (EC50= 14.9 mg/L).</p>Formula:C19H24N2O2Color and Shape:SolidMolecular weight:312.414-Hexen-3-one
CAS:<p>4-Hexen-3-one inhibits the growth of H. pylori in the ATCC 43526 strain and TDR strain. Additionally, this compound suppresses urease activity.</p>Formula:C6H10OColor and Shape:SolidMolecular weight:98.14FXR agonist 9
CAS:<p>FXR agonist9 (compound 26) is a selective, orally active partial agonist of FXR with an EC50 of 0.09 µM (maximum efficacy of 75.13%). It ameliorates the pathological features of fatty liver disease in mice induced by HFD and CCl4-related metabolic dysfunction.</p>Formula:C28H30N2O5Color and Shape:SolidMolecular weight:474.55Imipramine Blue chloride
<p>Imipramine Blue chloride is an effective anti-invasive agent capable of inhibiting glioma invasion. It suppresses the production of reactive oxygen species (reactive oxygen species) mediated by NADPH oxidase.</p>Formula:C40H51ClN4Color and Shape:SolidMolecular weight:623.31MAGL-IN-20
<p>MAGL-IN-20 (compound ±34) is a reversible inhibitor of monoacylglycerol lipase (MAGL). It exhibits significant antiproliferative activity against a range of cancer cell lines, including H460, HT29, CT-26, Huh7, and HCCLM-3.</p>Formula:C23H24N2OColor and Shape:SolidMolecular weight:344.45AChE/BChE-IN-23
<p>AChE/BChE-IN-23 (Compound 6e) is a dual inhibitor of acetylcholinesterase and butyrylcholinesterase, exhibiting IC50 values of 0.91 μM for AChE, 1.19 μM for eqBChE, and 1.01 μM for hBChE. This compound also demonstrates antioxidant properties and inhibits the aggregation of Aβ1-42 and Tau proteins. Moreover, AChE/BChE-IN-23 prevents the activation of microglial cells by inhibiting the release of reactive oxygen species and mitochondrial damage. Additionally, it reduces the levels of the NLRP3 inflammasome in human microglial cells and reverses memory impairment in mice induced by scopolamine.</p>Formula:C19H21N5O3Color and Shape:SolidMolecular weight:367.4NTPDase-IN-1
<p>NTPDase-IN-1 selectively inhibits NTPDases 1, 2, 8 with IC50 of 0.05, 0.23, 0.54 μM. Non-competitive, K m 21 μM, used in cancer, immune, infection research.</p>Formula:C18H25N3OS2Color and Shape:SolidMolecular weight:363.54α-Hydroxy alprazolam
CAS:<p>α-Hydroxy alprazolam (U 40125), the primary metabolite of α-Hydroxy alprazolam, possesses pharmacological activity accounting for 60% of that of Alprazolam.</p>Formula:C17H13ClN4OColor and Shape:SolidMolecular weight:324.76RO5101576
CAS:<p>RO5101576 is a potent antagonist of LTB4 receptor.</p>Formula:C36H38O8SPurity:98%Color and Shape:SolidMolecular weight:630.75BAY R3401
CAS:<p>BAY R3401 is an orally active inhibitor of glycogen phosphorylase, leading to irreversible and non-selective inhibition of liver glycogenolysis. It suppresses glycogen breakdown in hepatocytes with IC50 values of 27.06 μM in HL-7702 cells and 52.83 μM in HepG2 cells. BAY R3401 is applicable for research in type 2 diabetes.</p>Formula:C20H22ClNO4Color and Shape:SolidMolecular weight:375.846Valerate sodium
CAS:<p>Valerate sodium is a potential Carbonic anhydrase 1/2 inhibitor for biochemical experiments.</p>Formula:C5H9NaO2Purity:99.84%Color and Shape:SolidMolecular weight:124.11L-690330 hydrate
<p>L-690330 hydrate inhibits IMPase; Ki: 0.30 μM (human), 0.42 μM (bovine cortex); 0.27 μM (recom. human), 0.19 μM (bovine).</p>Formula:C8H14O9P2Color and Shape:SolidMolecular weight:316.14α-Amylase-IN-7
CAS:<p>α-Amylase-IN-7 (Compound 6e) is an inhibitor of α-Amylase, with an IC50 of 40 μM, indicating its potency. This compound shows potential as an anti-diabetic medication.</p>Formula:C18H15ClN6O2SMolecular weight:414.87PKR Inhibitor, negative control
CAS:<p>The PKR Inhibitor, negative control, is an inactive structural analog of RNA-dependent protein kinase (PKR) inhibitors, serving as a negative control. Additionally, it can inhibit LK-induced neuronal death, demonstrating significant neuroprotective properties.</p>Formula:C15H8Cl3NO2Molecular weight:340.59Anticancer agent 78
<p>Anticancer agent 78: anti-aromatase (IC50=0.9 μM), cytotoxic, potential in breast cancer research.</p>Formula:C19H14BrNO4Color and Shape:SolidMolecular weight:400.22RXR antagonist 1
<p>RXR antagonist 1 is a Retinoid X Receptor (RXR) modulator that exhibits high RXR antagonism (pA2: 8.06). RXR antagonist 1 can be used to study type 2 diabetes.</p>Formula:C28H33F3N2O3Color and Shape:SolidMolecular weight:502.57IDX375
CAS:<p>IDX375 is a non-nucleoside inhibitor that selectively targets the HCV NS5B enzyme. It shows promising selectivity for genotypes 1a and 1b. The structure and binding sites of IDX375 have been confirmed through X-ray co-crystallization studies.</p>Formula:C24H37N4O6PSColor and Shape:SolidMolecular weight:540.61ACLY-IN-1
CAS:<p>ACLY-IN-1 (compound 55) is a potent ACLY inhibitor with an IC50 of 8.3 nM, and it can be utilized in hyperlipidemia research.</p>Formula:C20H12BrClF2N2O4SColor and Shape:SolidMolecular weight:529.74SDX-7539
CAS:<p>SDX-7539 is a selective MetAP2 inhibitor that inhibits the proliferation of HUVEC, with an IC50 of 120 μM. It has demonstrated antitumor activity in xenografted NSCLC in athymic nude mice.</p>Formula:C23H38N2O5Molecular weight:422.5611-Mercaptoundecanoate-NHS
CAS:<p>11-Mercaptoundecanoate-NHS is a lipid utilized in the synthesis of Linkers.</p>Formula:C15H25NO4SColor and Shape:SolidMolecular weight:315.428Phospho-L-arginine
CAS:<p>Phospho-L-arginine is a derivative of arginine.</p>Formula:C6H15N4O5PMolecular weight:254.18BMS-185354
CAS:<p>BMS-185354 is a selective RARγ activator with an EC50 value of 28 nM, offering potential for cancer research.</p>Formula:C26H27NO3Color and Shape:SolidMolecular weight:401.497Propofol sulfate sodium
CAS:<p>Propofolsulfate (sodium) is a metabolite of Propofol.</p>Formula:C12H17NaO4SColor and Shape:SolidMolecular weight:280.316Enpp-1-IN-12
<p>ENPP1-IN-12 is a potent, oral ENPP1 inhibitor with a Ki of 41 nM and anti-tumor properties.</p>Formula:C17H19N5O3SColor and Shape:SolidMolecular weight:373.43Carbonic anhydrase inhibitor 17
CAS:<p>Carbonic anhydrase inhibitor 17 (compound 7c) is a pyrazine-based sulfonamide that acts as a carbonic anhydrase II inhibitor, with an IC50 value of 0.63 nM.</p>Formula:C18H15ClN4O3S2Molecular weight:434.92Casein kinase 1δ-IN-16
CAS:<p>Casein kinase1δ-IN-16 (compound 506) is an inhibitor of casein kinase 1δ (CK1δ). This compound is applicable in research related to neurodegenerative diseases.</p>Formula:C17H12N4S2Color and Shape:SolidMolecular weight:336.434PDE4-IN-12
<p>PDE4-IN-12 is a potent and safe PDE4 ubiquitous inhibitor that acts on PDE4 (IC50: 3.5 nM, SI: 2.71) and PDE7 (IC50: 15 nM, SI: 4.27).</p>Formula:C34H35NO6Color and Shape:SolidMolecular weight:553.64DPM-1003
CAS:<p>DPM-1003 is an allosteric inhibitor of PTP1B, targeting the non-catalytic, disordered C-terminal segment of the PTP1B protein, and has shown beneficial effects in reducing pulmonary inflammation in mice.</p>Formula:C35H57N3O3Color and Shape:SolidMolecular weight:567.845Lipoxin A5
CAS:<p>LXA5 is made from EPA by leukocytes, contracts guinea pig lungs like LXA4/LXB4, but doesn't dilate aorta.</p>Formula:C20H30O5Color and Shape:SolidMolecular weight:350.45PDE5-IN-8
CAS:<p>PDE5-IN-8 (compound 2) is an inhibitor of PDEs.</p>Formula:C22H20ClN3O2Color and Shape:SolidMolecular weight:393.87PDE4-IN-14
CAS:<p>PDE4-IN-14 (Compound 1) serves as an inhibitor of phosphodiesterase 4 (PDE4), applicable in research concerning diseases associated with PDE4, including</p>Formula:C19H20F2N4O3SColor and Shape:SolidMolecular weight:422.45hMAO-B/MB-COMT-IN-2
<p>Dual inhibitor hMAO-B/MB-COMT-IN-2 targets hMAO-B (IC50: 4.27μM) & MB-COMT (IC50: 2.69μM), aids in neurodegenerative research.</p>Formula:C17H18N2O3Color and Shape:SolidMolecular weight:298.34Lp-PLA2-IN-6
CAS:<p>Lp-PLA2-IN-6: Potent tetracyclic inhibitor of rhLp-PLA2, with pIC50 of 10.0, and potential in neurodegenerative research.</p>Formula:C25H21F5N4O3Color and Shape:SolidMolecular weight:520.45NSC 828467
<p>NSC 828467 is one of the top five CA-IX inhibitors with significant in vitro anticancer activity (IC50: 27.2 nM).</p>Formula:C21H19N9O2SColor and Shape:SolidMolecular weight:461.5SHP2-IN-9
<p>SHP2-IN-9: Potent SHP2 inhibitor, IC50=1.174 μM, 85x SHP1 selectivity, crosses blood-brain barrier, hampers cancer growth.</p>Formula:C20H20FN3O2SColor and Shape:SolidMolecular weight:385.46FTI-2148
CAS:<p>FTI-2148 blocks RAS-related FT-1 & GGT-1; IC50: 1.4 nM & 1.7 μM.</p>Formula:C24H28N4O3SPurity:98%Color and Shape:SolidMolecular weight:452.57GKA50 quarterhydrate
<p>GKA50 quarterhydrate: glucokinase activator, EC50 of 33 nM, boosts insulin, cuts glucose in rats.</p>Formula:C26H30N2O7Color and Shape:SolidMolecular weight:469.01Complex III-IN-2
<p>Complex III-IN-2 inhibits complex III, with antifungal EC50: 29.31 mg/L vs R. solani, 29.98 mg/L vs S. sclerotiorum.</p>Formula:C15H21ClN2O2SColor and Shape:SolidMolecular weight:328.86AD013
<p>AD013 is a selective ACE inhibitor and NEP inhibitor with potential anti-hypertensive and cardioprotective benefits.</p>Formula:C24H28N2O5Color and Shape:SolidMolecular weight:424.49FTI 276 TFA
CAS:<p>FTI 276 TFA targets plasmodium falciparum & humans, inhibits PFT with IC50s: 0.9 nM (parasite) & 0.5 nM (human).</p>Formula:C23H28F3N3O5S2Color and Shape:SolidMolecular weight:547.61AZD 4407
CAS:<p>AZD 4407 is a potent inhibitor of 5-lipoxygenase.</p>Formula:C19H21NO3S2Purity:98%Color and Shape:SolidMolecular weight:375.5LDHA-IN-5
CAS:<p>LDHA-IN-5 is a novel and potent inhibitor targeting both glycolate oxidase (GO) and lactate dehydrogenase A (LDHA), designed for the treatment of primary</p>Formula:C27H22FN7O6S3Color and Shape:SolidMolecular weight:655.7MAFP
CAS:<p>MAFP (Methyl Arachidonyl Fluorophosphonate) is an effective irreversible inhibitor of anandamide amidase.</p>Formula:C21H36FO2PColor and Shape:SolidMolecular weight:370.482-Amino-5-methyl-5-hexenoic acid
CAS:<p>2-Amino-5-methyl-5-hexenoic acid ((S)-2-Amino-5-methylhex-5-enoic acid) acts as a methionine analog, competing with methionine and thereby hindering cell growth. This compound inhibits protein synthesis in Salmonella typhimurium TA1535 and Escherichia coli K-12 without affecting the synthesis of DNA or RNA.</p>Formula:C7H13NO2Color and Shape:SolidMolecular weight:143.184
