Metabolism
Metabolism inhibitors are compounds that interfere with metabolic pathways, altering the production and utilization of energy within cells. These inhibitors are used to study the regulation of metabolism, the role of metabolic pathways in diseases like cancer and diabetes, and to develop new therapeutic strategies. Metabolism inhibitors can target various enzymes and processes involved in glycolysis, fatty acid oxidation, and other metabolic functions. At CymitQuimica, we offer a wide range of high-quality metabolism inhibitors to support your research in biochemistry, metabolic disorders, and drug development.
Subcategories of "Metabolism"
- AhR(41 products)
- Aminopeptidase(67 products)
- CETP(18 products)
- Carbonic Anhydrase(177 products)
- Casein Kinase(130 products)
- DHFR(32 products)
- Decarboxylase(4 products)
- Dehydrogenase(267 products)
- FAAH(63 products)
- FXR(58 products)
- Factor Xa(80 products)
- Fatty Acid Synthase(32 products)
- Ferroptosis(215 products)
- GR(3 products)
- GSNOR(3 products)
- Glucokinase(53 products)
- HIF/HIF Prolyl-Hydroxylase(142 products)
- HMG-CoA Reductase(32 products)
- Hydroxylase(30 products)
- IDO(82 products)
- LDL(8 products)
- Lipase(96 products)
- Lipid(59 products)
- Lipoxygenase(124 products)
- MAO(87 products)
- MPO(2 products)
- NAMPT(36 products)
- P450(6 products)
- PAI-1(25 products)
- PDE(165 products)
- PED(1 products)
- PKM(15 products)
- PPAR(164 products)
- Phospholipase(82 products)
- ROR(42 products)
- Retinoid Receptor(29 products)
- SGK(11 products)
- Thioredoxin(12 products)
- Transferase(30 products)
- Transporter(42 products)
- UGT(4 products)
- Xanthine Oxidase (XO) Inhibitors(9 products)
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Found 8597 products of "Metabolism"
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Pyrocatechol sulfate
CAS:<p>Pyrocatechol sulfate, a phenolic metabolite found in human plasma, is associated with the intake of specific foods such as berries and the state of the gut microbiome. It serves as a potential urinary biomarker for kidney function, dialysis clearance rates, whole grain consumption, and regular coffee intake. Additionally, in conjunction with other phenolic sulfates, pyrocatechol sulfate plays a role in regulating various biological functions, including those related to brain health and the rhythmic beating of cardiac cells.</p>Formula:C6H6O5SColor and Shape:SolidMolecular weight:190.17AubipyOMe
CAS:<p>AubipyOMe serves as an effective inhibitor of Tartrate-resistant Acid Phosphatase (TRAP/ACP5), a metalloenzyme identified in activated osteoclasts and macrophages. It exhibits inhibitory IC50 values of 1.3 μM against TRAP5a and 1.8 μM against TRAP5b. Additionally, it effectively suppresses TRAP activity in extracts from mouse macrophages and human lung tissues.</p>Formula:C12H12AuCl2F6N2O2PColor and Shape:SolidMolecular weight:629.07Homomoschatoline
CAS:<p>Homomoschatoline is an antibacterial isolated from Artabotrys crassifolius.</p>Formula:C19H15NO4Purity:98%Color and Shape:SolidMolecular weight:321.33(S)-Dexfadrostat
CAS:<p>(S)-Dexfadrostat ((S)-Fadrozole), an aromatase inhibitor, exhibits an IC 50 of 4.6 nM in in vitro assays using human placental microsomes. It is applicable for research on estrogen-dependent breast cancer, gynecomastia, and systemic lupus erythematosus.</p>Formula:C14H13N3Color and Shape:SolidMolecular weight:223.27IDX375
CAS:<p>IDX375 is a non-nucleoside inhibitor that selectively targets the HCV NS5B enzyme. It shows promising selectivity for genotypes 1a and 1b. The structure and binding sites of IDX375 have been confirmed through X-ray co-crystallization studies.</p>Formula:C24H37N4O6PSColor and Shape:SolidMolecular weight:540.617PPD-Q
CAS:<p>7PPD-Q is a substituted p-phenylenediamine antioxidant derivative. It exhibits toxicity towards the bacterium V. fischeri (EC50= 14.9 mg/L).</p>Formula:C19H24N2O2Color and Shape:SolidMolecular weight:312.41Lp-PLA2-IN-5
CAS:<p>Lp-PLA2-IN-5 inhibits Lp-PLA2 and PAF-AH, potentially useful in Alzheimer's and atherosclerosis studies.</p>Formula:C23H18F5N3O4Color and Shape:SolidMolecular weight:495.4BRD7539
CAS:<p>BRD7539B: PfDHODH inhibitor, IC50 0.033μM; selective vs HsDHODH, IC50 >50μM.</p>Formula:C23H22FN3O2Purity:98%Color and Shape:SolidMolecular weight:391.44IDO1-IN-14
<p>IDO1-IN-14 is an IDO1 enzyme inhibitor with an IC50 of 396.9 nM and suppresses HeLa cell activity with an EC50 of 3393 nM.</p>Formula:C18H12Cl2FN3O2Color and Shape:SolidMolecular weight:392.212R,4S-Sacubitril
CAS:<p>2R,4S-Sacubitril (Sacubitril Enantiomer) is the impurity of Sacubitril which is a neprilysin inhibitor.</p>Formula:C24H28NO51CaPurity:98%Color and Shape:SolidMolecular weight:430.49Zaragozic acid C
CAS:<p>Zaragozic acid C is an effective inhibitor of squalene synthase.</p>Formula:C40H50O14Purity:98%Color and Shape:SolidMolecular weight:754.82GGACK
CAS:<p>GGACK (H-Glu-Gly-Arg-CMK) is an irreversible substrate-like inhibitor of the serine protease urokinase-type plasminogen activator (uPA).</p>Formula:C14H25ClN6O5Molecular weight:392.84Mucidin
CAS:<p>Mucidin is an antifungal antibiotic that inhibits electron transfer reactions within the mitochondrial respiratory chain's cytochrome bc1 complex.</p>Formula:C16H18O3Molecular weight:258.311-Phenylethanamine
CAS:<p>1-Phenylethanamine, a potential central nervous system stimulant related to β-phenylethylamine (β-phenylethylamine), exhibits diminished glycogenolysis activity in the brain due to its benzene ring being replaced by an indole group. This reduction in activity makes it useful for investigating how the chemical structure of phenylethylamine derivatives influences their effects on the central nervous system. Additionally, 1-Phenylethanamine is also utilized in the synthesis of the tyrosine kinase (tyrosine kinase) inhibitor CLM3.</p>Formula:C8H11NColor and Shape:SolidMolecular weight:121.184-MDM
CAS:<p>4-MDM (4-Methoxydiphenylmethane) is an orally active anti-inflammatory compound that selectively enhances the aminopeptidase activity of leukotriene A4 hydrolase (LTA4H). By promoting the degradation of proline-glycine-proline by LTA4H, 4-MDM reduces neutrophil recruitment in the lungs, alleviating inflammation without affecting the epoxide hydrolase activity of LTA4H. This compound is useful for research in pulmonary diseases.</p>Formula:C14H14OColor and Shape:SolidMolecular weight:198.26DS44470011
CAS:<p>DS44470011 is an inhibitor of hypoxia-inducible factor prolyl hydroxylase (HIF-PHD) with oral bioavailability. It enhances the release of erythropoietin (EPO) from cells and is utilized in research related to renal anemia.</p>Formula:C21H19N3O4Color and Shape:SolidMolecular weight:377.39GlcCer (d18:1/18:0)
CAS:<p>GlcCer (d18:1/18:0) (C18 Glucosyl(β) ceramide (d18:1/18:0)) is a sphingolipid with potential applications in research on Parkinson's disease and Lewy body dementia.</p>Formula:C42H81NO8Color and Shape:SolidMolecular weight:728.094DEL-I25
CAS:<p>DEL-I25 is an effective activator of GPX4 that protects cells from ferroptosis (iron-dependent cell death).</p>Formula:C21H23N5O3Color and Shape:SolidMolecular weight:393.44MAGL-IN-15
CAS:<p>MAGL-IN-15 (Compound 6), a MAGL inhibitor, holds potential for research into diseases and disorders associated with the regulation of endocannabinoid system signaling activities [1].</p>Formula:C16H16F6N4O3Color and Shape:SolidMolecular weight:426.31ABHD antagonist 1
CAS:<p>ABHD antagonist 1 is an inhibitor of ABHD6 (α/β-Hydrolase domain containing 6), involved in modulating biochemical pathways affected by ABHD6, thereby influencing cell function and inflammatory responses. This compound is applicable for research in fields such as pain, neurological disorders, inflammatory diseases, autoimmune diseases, metabolic disorders, and cancer.</p>Formula:C19H20BrN3O3SColor and Shape:SolidMolecular weight:450.35Nampt activator-4
CAS:<p>Nampt activator-4, a positive allosteric modulator (N-PAM) of nicotinamide phosphoribosyltransferase (NAMPT), has an EC50 of 0.058 μM and can enhance nicotinamide adenine dinucleotide (NAD+) levels in cells [1].</p>Formula:C26H22F3N7OSColor and Shape:SolidMolecular weight:537.56α-Glucosidase-IN-63
CAS:<p>α-Glucosidase-IN-63 (Compound 4d) serves as an α-Glucosidase inhibitor with an IC 50 value of 0.44 μM. Additionally, it exhibits inhibitory activity against hCA II, demonstrating a K i of 7.0 nM. The compound is also effective when administered orally. [1]</p>Formula:C16H12FN3O3S2Color and Shape:SolidMolecular weight:377.41ABCB1-IN-4
CAS:<p>ABCB1-IN-4 (Compound C6z) is an orally active inhibitor of α-amylase and α-glucosidase, with IC50 values of 1.63 μM and 0.14 μM, respectively. It holds potential for diabetes research.</p>Formula:C16H14N4SColor and Shape:SolidMolecular weight:294.374TAK-828F
CAS:<p>TAK-828F: potent, selective RORγt inverse agonist. Oral. IC50=1.9 nM; reporter gene IC50=6.1 nM.</p>Formula:C28H32FN3O5Purity:98%Color and Shape:SolidMolecular weight:509.57Etiocholanolone glucuronide
CAS:<p>Etiocholanolone glucuronide (Etio-G) is a metabolite of Etiocholanolone, produced through the catalysis by UDP glucuronosyltransferase in the liver. Etiocholanolone glucuronide shows potential for research in metabolic-related diseases.</p>Formula:C25H38O8Color and Shape:SolidMolecular weight:466.564PTP1B-IN-16
<p>PTP1B-IN-16: selective benzimidazole inhibitor of PTP1B, Ki: 12.6 μM, potential for type 2 diabetes research.</p>Formula:C26H18ClN3O4SColor and Shape:SolidMolecular weight:503.96ZSH-2208
CAS:<p>ZSH-2208 is a retinoic acid A analogue that inhibits tumour cell proliferation and survival through RARγ-TNFAIP3 and retinoid receptors.</p>Formula:C20H18O3SPurity:99.81%Color and Shape:SolidMolecular weight:338.42Anticancer agent 142
CAS:<p>Compound 142 (also known as Compound 235) is a PTPN inhibitor with potential applications in cancer research [1].</p>Formula:C13H14BrF2N2O7PS2Purity:98%Color and Shape:SolidMolecular weight:523.26LXR agonist 2
<p>LXR agonist 2 is a potent agonist of the LXR (liver X receptor). LXR agonist 2 stabilises NCOA1 (coactivator), which in turn agonises the LXR.</p>Formula:C35H40ClN3O3Color and Shape:SolidMolecular weight:586.16VHR-IN-1
CAS:<p>VHR-IN-1 (Compound SA1) is an effective and selective VHR phosphatase inhibitor with an IC50 of 18 nM. It hinders the proliferation of cervical cancer cells, demonstrating antitumor activity.</p>Formula:C28H22ClN3O5S3Color and Shape:SolidMolecular weight:612.139TS010
<p>TS010 is a highly potent inhibitor of GLO-I, with an IC50 value of 0.57 μM. It holds significant promise for advancements in cancer research [1].</p>Formula:C16H12N4O4SColor and Shape:SolidMolecular weight:356.36Casein kinase 1δ-IN-18
CAS:<p>Casein kinase1δ-IN-18 (compound 660) is an inhibitor of casein kinase 1δ (CK1δ), which can be utilized for research in neurodegenerative diseases.</p>Formula:C16H12ClN3O2S2Color and Shape:SolidMolecular weight:377.868Fluopimomide
CAS:<p>Fluopimomide (LH2010A), a powerful insecticide, is extensively utilized in the control of agricultural pests. It adversely affects the growth, locomotor behavior, reproduction, and lifespan of nematodes. Concurrently, it leads to increased production of reactive oxygen species (ROS), accumulation of lipids and lipofuscins, as well as a rise in malondialdehyde content. Additionally, Fluopimomide inhibits the antioxidant system of nematodes.</p>Formula:C15H8ClF7N2O2Color and Shape:SolidMolecular weight:416.68Deltasonamide 2 hydrochloride
<p>Deltasonamide 2 hydrochloride is a competitive high-affinity PDEδ inhibitor with a Kd of approximately 385 pM.</p>Formula:C30H40Cl2N6O4S2Purity:98%Color and Shape:SolidMolecular weight:683.71BAY-179
CAS:<p>BAY-179 is a potent, selective, species cross-reactive complex I inhibitor for the study of cancer.</p>Formula:C23H21N5OSPurity:98.29%Color and Shape:SolidMolecular weight:415.51BMS453
CAS:<p>BMS453 (BMS-189453), a synthetic retinoid, is a potent and selective agonist of RARβ and a potent testicular toxin.</p>Formula:C27H24O2Purity:99.93%Color and Shape:SolidMolecular weight:380.48CP-642931
CAS:<p>CP-642931 (Sorbitol dehydrogenase-IN-1) is a sorbitol dehydrogenase inhibitor used in the study of diabetes mellitus and cardiovascular disease.</p>Formula:C17H25N7OPurity:99.67% - >99.99%Color and Shape:SolidMolecular weight:343.43Aleglitazar
CAS:<p>Aleglitazar (R1439) (R1439) is a potent dual PPARα/γ agonist, with IC50s of 38 nM and 19 nM for human PPARa and PPARγ, respectively.</p>Formula:C24H23NO5SPurity:99.03%Color and Shape:SolidMolecular weight:437.51PREP inhibitor-1
CAS:<p>PREP inhibitor-1 is a prolyl oligopeptidase (PREP) inhibitor for the study of Alzheimer's disease.</p>Formula:C22H28N4O2Purity:98.78%Color and Shape:SoildMolecular weight:380.48Dual FAAH/sEH-IN-1
CAS:<p>Dual FAAH/sEH-IN-1 inhibits both sEH (IC50: 9.6 nM) and FAAH (IC50: 7 nM), offering potent anti-inflammatory effects.</p>Formula:C25H22ClN3O3S2Purity:99.89%Color and Shape:SolidMolecular weight:512.04DRB18
CAS:<p>DRB18 inhibits GLUT proteins, altering glucose metabolism and inducing cancer cell death by G1/S arrest and oxidative stress.</p>Formula:C22H23ClN2O2Purity:99.54%Color and Shape:SolidMolecular weight:382.88BAY-3827
CAS:<p>BAY-3827 is an AMPK inhibitor with antiproliferative activity and antitumor activity. BAY-3827 inhibits the phosphorylation of acetyl CoA carboxylase 1.</p>Formula:C27H25FN6OPurity:99.90%Color and Shape:SolidMolecular weight:468.53JNJ-6204
CAS:<p>JNJ-6204 is a deuterated compound that efficiently inhibits CSNK1D and CSNK1E.</p>Formula:C19H11D6FN6OPurity:97.42% - 99.87%Color and Shape:SolidMolecular weight:370.41Obicetrapib
CAS:<p>Obicetrapib (AMG-899) is an inhibitor of cholesteryl ester transfer protein.</p>Formula:C32H31F9N4O5Purity:99.26% - >99.99%Color and Shape:SolidMolecular weight:722.6Etamicastat hydrochloride
CAS:<p>Etamicastat hydrochloride (BIA 5-453 hydrochloride) is a peripherally selective dopamine beta-hydroxylase inhibitor that reduces hypertension.</p>Formula:C14H16ClF2N3OSPurity:98.54%Color and Shape:SolidMolecular weight:347.81FABPs ligand 6
CAS:<p>FABPs ligand 6 (MF6) is an inhibitor of FABP5 and FABP7.</p>Formula:C28H27FN2O3Purity:97.45%Color and Shape:SolidMolecular weight:458.52Glycosyltransferase-IN-1
<p>Glycosyltransferase-IN-1 is a glycosyltransferase inhibitor with bacteriostatic activity, inhibiting MSSA, MRSA, Bacillus subtilis, and Enterobacteriaceae.</p>Formula:C19H21N5OPurity:99.76%Color and Shape:SolidMolecular weight:335.4Lapaquistat acetate
CAS:<p>Lapaquistat acetate (TAK-475) is a squalene synthase inhibitor that reduces the cytotoxicity induced by statins in human skeletal muscle cells.</p>Formula:C33H41ClN2O9Purity:99.38% - 99.94%Color and Shape:SolidMolecular weight:645.14BE1218
CAS:<p>BE1218 is a liver X receptor (LXR) inverse agonist active on LXRα and LXRβ with an IC50 of 9 nM and 7 nM, respectively.</p>Formula:C30H30FNO4S2Purity:99.7%Color and Shape:SoildMolecular weight:551.69Moiramide B
CAS:<p>Moiramide B is an acetyl coenzyme A carboxylase inhibitor with antimicrobial activity, strongly inhibiting Gram-positive bacteria.</p>Formula:C25H31N3O5Purity:98.53% - 99.90%Color and Shape:SolidMolecular weight:453.53
