Metabolism
Metabolism inhibitors are compounds that interfere with metabolic pathways, altering the production and utilization of energy within cells. These inhibitors are used to study the regulation of metabolism, the role of metabolic pathways in diseases like cancer and diabetes, and to develop new therapeutic strategies. Metabolism inhibitors can target various enzymes and processes involved in glycolysis, fatty acid oxidation, and other metabolic functions. At CymitQuimica, we offer a wide range of high-quality metabolism inhibitors to support your research in biochemistry, metabolic disorders, and drug development.
Subcategories of "Metabolism"
- AhR(41 products)
- Aminopeptidase(67 products)
- CETP(18 products)
- Carbonic Anhydrase(177 products)
- Casein Kinase(130 products)
- DHFR(32 products)
- Decarboxylase(4 products)
- Dehydrogenase(267 products)
- FAAH(63 products)
- FXR(58 products)
- Factor Xa(80 products)
- Fatty Acid Synthase(32 products)
- Ferroptosis(215 products)
- GR(3 products)
- GSNOR(3 products)
- Glucokinase(53 products)
- HIF/HIF Prolyl-Hydroxylase(142 products)
- HMG-CoA Reductase(32 products)
- Hydroxylase(30 products)
- IDO(82 products)
- LDL(8 products)
- Lipase(96 products)
- Lipid(59 products)
- Lipoxygenase(124 products)
- MAO(87 products)
- MPO(2 products)
- NAMPT(36 products)
- P450(6 products)
- PAI-1(25 products)
- PDE(165 products)
- PED(1 products)
- PKM(15 products)
- PPAR(164 products)
- Phospholipase(82 products)
- ROR(42 products)
- Retinoid Receptor(29 products)
- SGK(11 products)
- Thioredoxin(12 products)
- Transferase(30 products)
- Transporter(42 products)
- UGT(4 products)
- Xanthine Oxidase (XO) Inhibitors(9 products)
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Found 8597 products of "Metabolism"
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3,4-Dihydroxyamphetamine hydrochloride
CAS:<p>3,4-Dihydroxyamphetamine (α-Methyldopamine) (hydrochloride) is a minor metabolite of 3,4-Methylenedioxymethamphetamine (MDMA) and exhibits cytotoxicity in rat hepatocytes. Additionally, 3,4-Dihydroxyamphetamine (hydrochloride) is applicable in hypertension research.</p>Formula:C9H14ClNO2Color and Shape:SolidMolecular weight:203.67LH1513
<p>LH1513 is a dioxalate salt derivative of l-lysine that inhibits CaOx crystallization more effectively than citrate and pyruvate. It shows potential preventive activity in hyperoxaluria models and effectively prevents urinary CaOx crystal formation in Agxt knockout mice. AGXT-1 is a mitochondrial protein involved in metabolic processes.</p>Formula:C10H11N2Na3O8Color and Shape:SolidMolecular weight:356.17L-Lysine, sulfite (2:1)
CAS:<p>L-Lysine, sulfite (2:1) is a drug/ therapeutic agent.</p>Formula:C6H14N2O2H2O3SColor and Shape:SolidMolecular weight:187.232-Hydroxy atorvastatin lactone
CAS:<p>2-Hydroxy atorvastatin lactone, a metabolite of Atorvastatin, is an orally active HMG-CoA reductase inhibitor that efficiently reduces blood lipids [1][2].</p>Formula:C33H33FN2O5Color and Shape:SolidMolecular weight:556.62Archangelicin
CAS:<p>Archangelicin is a useful organic compound for research related to life sciences. The catalog number is T125179 and the CAS number is 2607-56-9.</p>Formula:C24H26O7Color and Shape:SolidMolecular weight:426.465FP-Biotin
CAS:<p>FP-biotin: organophosphorus toxicant for biomarker discovery, targets FAAH, ABHD6, MAG-lipase in plasma via avidin-bead purification.</p>Formula:C27H50FN4O5PSColor and Shape:SolidMolecular weight:592.75ZG-2033
CAS:<p>ZG-2033 (Compound 26) is an orally active HIF-2α agonist that exhibits nanomolar activity (EC50 = 490 nM) in a luciferase reporter assay. It demonstrates an anti-anemic effect and shows synergistic effects with AKB-6548 in anemia, making it useful for the study of renal anemia.</p>Formula:C15H14N2O2SColor and Shape:SolidMolecular weight:286.35Cyano-myracrylamide
CAS:<p>Cyano-myracrylamide is an inhibitor of zinc finger DHHC domain-containing palmitoyltransferase 20 (zDHHC20) with an IC50 value of 1.35 µM. It also inhibits the S-palmitoylation of EGFR and CD36. In HEK293T cells expressing recombinant E. coli GobX, recombinant human MyD88, or endogenous Ras, Cyano-myracrylamide inhibits the S-palmitoylation of E. coli E3 ligase GobX, MyD88, and Ras, which are substrates of zDHHC20, zDHHC9, and zDHHC6.</p>Formula:C19H34N2OColor and Shape:SolidMolecular weight:306.49Bipolamine G
CAS:<p>Bipolamine G is an antibacterial polyketide alkaloid [1] .</p>Formula:C21H28N2O4Color and Shape:SolidMolecular weight:372.46FXR agonist 11
CAS:<p>FXR agonist11 (Compound 14) is an FXR activator with an EC50 of 1.2 μM and a maximal effect of 73.7%. It significantly increases GSH levels in the liver and is used to study drug-induced liver injury.</p>Formula:C18H16N2O5Color and Shape:SolidMolecular weight:340.33Kouitchenside G
CAS:<p>Kouitchenside G, a natural compound extracted from Swertia kouitchensis, demonstrates inhibitory activity against α-Glucosidase, showcasing an IC 50 value of</p>Formula:C27H32O15Color and Shape:SolidMolecular weight:596.53LH10
<p>LH10 is an FXR agonist based on fexaramine, with an EC50 of 0.14 μM. It offers hepatoprotective effects, mitigating conditions such as cholestasis induced by alpha naphthylisothiocyanate (ANIT), acute liver injury caused by APAP, and non-alcoholic steatohepatitis (NASH).</p>Formula:C34H33N3O2Color and Shape:SolidMolecular weight:515.6413-cis-Vitamin A palmitate
CAS:<p>13-cis-Retinyl palmitate in corn flakes is 75% as active as all-trans form.</p>Formula:C36H60O2Color and Shape:SolidMolecular weight:524.86Anticancer agent 260
CAS:<p>Anticanceragent 260 (Compound 3g/4d) is an orally effective anticancer agent that inhibits the proliferation of cancer cells HCT-116, MIA-PaCa2, and MDA-MB231, with IC50 values of 98.7, 81.0, and 77.2 µg/mL, respectively. It also promotes ulcer formation and lipid peroxidation, and exhibits anti-inflammatory and analgesic activities.</p>Formula:C14H11N3OColor and Shape:SolidMolecular weight:237.26Ingenol disoxate
CAS:<p>Ingenol disoxate (LEO43204) is a compound for treating actinic keratosis, a natural Euphorbia peplus extract.</p>Formula:C28H37NO7Color and Shape:SolidMolecular weight:499.6Oxytetracycline calcium
CAS:<p>Oxytetracycline calcium is a tetracycline antibiotic effective against Gram-negative and Gram-positive bacteria, inhibits protein synthesis, and fights HSV-1.</p>Formula:C22H22CaN2O9Color and Shape:SolidMolecular weight:498.502-Amino-5-bromo-2’-chlorobenzophenone
CAS:<p>2-Amino-5-bromo-2’-chlorobenzophenone is an active metabolite of Phenazepam.</p>Formula:C13H9BrClNOColor and Shape:SolidMolecular weight:310.57FXR agonist 10
<p>FXR agonist10 (Compound 27) acts as an agonist for FXR with an EC50 of 14.26 μM. It increases the expression of SHP and BSEP proteins while decreasing the expression of NTCP and CYP7A1 proteins. Additionally, FXR agonist10 has been shown to ameliorate ANIT-induced cholestasis in mouse models.</p>Formula:C15H22O4Color and Shape:SolidMolecular weight:266.33ND-011992
CAS:<p>ND-011992: Quinazoline inhibitor of E. coli respiratory enzymes; IC50s: 0.12-2.47 μM; potential tuberculosis research.</p>Formula:C21H14F3N3OPurity:99.7%Color and Shape:SoildMolecular weight:381.35PPARγ agonist 15
<p>PPARγ agonist15 (Compound 7c) functions as an agonist of PPARγ, inhibiting the expression of α-amylase (HPA) and α-glucosidase (HLAG) with IC50 values of 28.35 µM and 26.21 µM, respectively. It enhances glucose uptake in L6 myotubes and improves glucose homeostasis, insulin sensitivity, and lipid metabolism in a rat model of Streptozotocin-induced diabetes.</p>Formula:C21H16N4O3S2Color and Shape:SolidMolecular weight:436.51(3R,5R)-Octahydrocurcumin
CAS:<p>(3R,5R)-Octahydrocurcumin (Compound 7) is a metabolite of Curcumin produced by gut microbiota. It exhibits neuroprotective effects against Aβ25-35-induced cell damage in SH-SY5Y cells and possesses anti-inflammatory properties in LPS-stimulated BV-2 mouse microglia.</p>Formula:C21H28O6Color and Shape:SolidMolecular weight:376.44Xanthine oxidase-IN-9
CAS:<p>Xanthine Oxidase-IN-9 (also known as Icarisids E or Compound 2) effectively inhibits xanthine oxidase (XOD) with an IC50 value of 31.81 μM [1].</p>Formula:C38H50O20Color and Shape:SolidMolecular weight:826.79APOL1-IN-2
CAS:<p>APOL1-IN-2 (Compound 467) acts as an inhibitor of apolipoprotein L1 (APOL1). It effectively reduces HEK293 cell death induced by APOL1 G2/G1, with EC50 values of 4.74 nM and 14.3 nM, respectively. Additionally, APOL1-IN-2 decreases the mortality of trypanosomes triggered by APOL1 G2/G1/G0, with EC50 values of 2.24, 6.03, and 3.72 nM, respectively.</p>Formula:C28H30ClF3N4O5Color and Shape:SolidMolecular weight:595.01Norpropranolol hydrochloride
CAS:<p>Norpropranolol hydrochloride is the active metabolite of Propranolol.</p>Formula:C13H16ClNO2Color and Shape:SolidMolecular weight:253.73Febuxostat impurity 6
CAS:<p>Febuxostat impurity 6 is an impurity of Febuxostat. Febuxostat is selective xanthine oxidase inhibitor with a K i of 0.6 nM [1] .</p>Formula:C18H22N2O4SColor and Shape:SolidMolecular weight:362.44BMT-124110 Formate
<p>BMT-124110 Formate is a selective AAK1 inhibitor (IC50: 0.9 nM) with anti-injury sensory activity.BMT-124110 Formate inhibits the BMP-2-inducible protein kinase</p>Formula:C22H20N2O2Purity:99.52%Color and Shape:SoildMolecular weight:344.41α-1,4-Galactosyltransferase (LgtC)
CAS:<p>A4GALT (LgtC) adds galactose to lactosylceramide, forming globotriaosylceramide; used in P1 antigen synthesis.</p>Color and Shape:SolidAbiraterone sulfate
CAS:<p>Abiraterone sulfate is a metabolite of Abiraterone . Abiraterone is a potent and irreversible CYP17A1 inhibitor with antiandrogen activity [1] .</p>Formula:C24H31NO4SColor and Shape:SolidMolecular weight:429.57Phenylsulfamide
CAS:<p>Phenylsulfamide (Compound 10), acting as an inhibitor of human carbonic anhydrase-II (hCA-II), exhibits a dissociation constant (Kd) of 45.50 μM and an</p>Formula:C6H8N2O2SColor and Shape:SolidMolecular weight:172.21-Salicylate Glucuronide
CAS:<p>1-Salicylate Glucuronide (Salicylic Acid b-D-O-Glucuronide) is a metabolite of salicylic acid after glucuronidation, promoting excretion.</p>Formula:C13H14O9Color and Shape:SolidMolecular weight:314.25OPC 8490 free base
CAS:<p>OPC 8490 free base is a positive inotropic vasodilator and a cardiotonic agent that can be used to study cardiovascular diseases.</p>Formula:C24H27N3O3Purity:99.53%Color and Shape:SoildMolecular weight:405.49DMPG sodium
CAS:<p>DMPG sodium is a phospholipid analog commonly used in the preparation of artificial lipid bilayers to mimic the structure and function of biological membranes.</p>Formula:C34H66NaO10PPurity:99.05%Color and Shape:SolidMolecular weight:688.85Anti-ANGPTL4 Antibody
<p>Anti-ANGPTL4 Antibody is a humanized antibody targeting ANGPTL4.</p>Purity:99.4% (SDS-PAGE); 98.4% (SEC-HPLC) - 99.4% (SDS-PAGE); 98.4% (SEC-HPLC)Color and Shape:Odour Liquid6α-hydroxy Paclitaxel
CAS:<p>6α-hydroxy Paclitaxel (6α-OH-PTX) is a major metabolite of the anticancer compound paclitaxel and is partially cytotoxic.</p>Formula:C47H51NO15Purity:99.33%Color and Shape:SolidMolecular weight:869.91TDI-11055
<p>TDI-11055 is a chromatin reader 11-19 leukemia inhibitor and can be used to study acute myeloid leukemia (AML).</p>Formula:C22H24N6OPurity:98.48%Color and Shape:SolidMolecular weight:388.47Ganoderenic acid K
CAS:<p>Ganoderenic acid K, from Ganoderma lucidum, inhibits HMG-CoA reductase with an IC50 of 16.5 μM.</p>Formula:C32H44O9Color and Shape:SolidMolecular weight:572.69GW6340
CAS:<p>GW6340 is a selective LXR agonist with potential anticancer activity that promotes macrophage reverse cholesterol transport (mRCT) and can be used to study atherosclerosis.</p>Formula:C33H32ClF3N2O2Purity:99.79%Color and Shape:SoildMolecular weight:581.07Alfacalcidol-D6
CAS:<p>Alfacalcidol-D6 is a deuterated Alfacalcidol. Alfacalcidol is a non-selective VDR activator medication.</p>Formula:C27H44O2Purity:98%Color and Shape:SolidMolecular weight:406.67SKI2852
CAS:<p>SKI2852 is an 11β-HSD1 inhibitor that improves metabolic syndrome in diabetic mouse models.</p>Formula:C27H34FN5O4SPurity:99.89%Color and Shape:SolidMolecular weight:543.653,5,6,7,8,4′-hexamethoxyflavone
CAS:<p>3,5,6,7,8,4′-hexamethoxyflavone is a natural product for research related to life sciences. The catalog number is TN7114 and the CAS number is 34170-18-8.</p>Formula:C21H22O8Color and Shape:SolidMolecular weight:402.399Guignardone J
CAS:<p>Guignardone J, a secondary metabolite, is isolated from the endophytic fungus Phyllosticta capitalensis [1].</p>Formula:C17H24O5Color and Shape:SolidMolecular weight:308.37Milpocitide
CAS:<p>Milpocitide, a (293-333)-peptide fragment of the human low-density lipoprotein receptor (LDLR), specifically corresponds to the EGF-like domain 1 [1].</p>Formula:C255H413N63O86S6Color and Shape:SolidMolecular weight:5929.75N-Methyl pemetrexed
CAS:<p>N-Methyl pemetrexed, an impurity found in Pemetrexed, serves as an antifolate cytotoxic agent utilized in cancer research [1].</p>Formula:C21H23N5O6Color and Shape:SolidMolecular weight:441.44DMPS-Na
CAS:<p>DMPS-Na is an arsenicolytic agent with toxicity that can be used to study cell membranes.</p>Formula:C34H65NNaO10PPurity:98%Color and Shape:SoildMolecular weight:701.84AP219
CAS:<p>AP39 boosts mitochondrial H2S with triphenylphosphonium and dithiolethione; AP219 lacks H2S-donating part.</p>Formula:C28H34O2PColor and Shape:SolidMolecular weight:433.551Ferulic acid acyl-β-D-glucoside
CAS:<p>Ferulic acid acyl-β-D-glucoside, a metabolite of Ferulic Acid, is a novel inhibitor of fibroblast growth factor receptor 1 (FGFR1).</p>Formula:C16H20O9Color and Shape:SolidMolecular weight:356.327Adenosylhomocysteinase
CAS:<p>SAHH, an enzyme, reversibly converts SAH into adenosine and L-homocysteine, and may predict HBV-LC outcomes.</p>Formula:C14H13N3O2S2Color and Shape:SolidMolecular weight:319.04492IGUANA-1 free base
CAS:<p>IGUANA-1: selective ALDH1 B1 inhibitor, IC50=30 nM, hinders SW480 cell growth with IC50=2.46/0.39 μM in adherent/spheroid forms, for cancer research.</p>Formula:C26H24ClN3O2Color and Shape:SolidMolecular weight:445.94Morin 3-O-β-D-glucopyranoside
CAS:<p>Morin 3-O-β-D-glucopyranoside, a natural flavonoid, exhibits antifungal, anticancer, and antioxidant properties.</p>Formula:C21H20O12Color and Shape:SolidMolecular weight:464.38Endoglycoceramidase II (EGCase II)
CAS:<p>EGCase II is an enzyme breaking down the glycan-ceramide bond in glycosphingolipids.</p>Color and Shape:Solid
