Metabolism
Metabolism inhibitors are compounds that interfere with metabolic pathways, altering the production and utilization of energy within cells. These inhibitors are used to study the regulation of metabolism, the role of metabolic pathways in diseases like cancer and diabetes, and to develop new therapeutic strategies. Metabolism inhibitors can target various enzymes and processes involved in glycolysis, fatty acid oxidation, and other metabolic functions. At CymitQuimica, we offer a wide range of high-quality metabolism inhibitors to support your research in biochemistry, metabolic disorders, and drug development.
Subcategories of "Metabolism"
- AhR(42 products)
- Aminopeptidase(76 products)
- CETP(20 products)
- Carbonic Anhydrase(196 products)
- Casein Kinase(139 products)
- DHFR(30 products)
- Decarboxylase(4 products)
- Dehydrogenase(302 products)
- FAAH(64 products)
- FXR(62 products)
- Factor Xa(87 products)
- Fatty Acid Synthase(37 products)
- Ferroptosis(227 products)
- GR(3 products)
- GSNOR(3 products)
- Glucokinase(56 products)
- HIF/HIF Prolyl-Hydroxylase(146 products)
- HMG-CoA Reductase(34 products)
- Hydroxylase(36 products)
- IDO(84 products)
- LDL(7 products)
- Lipase(107 products)
- Lipid(62 products)
- Lipoxygenase(133 products)
- MAO(85 products)
- MPO(2 products)
- NAMPT(40 products)
- P450(6 products)
- PAI-1(26 products)
- PDE(170 products)
- PED(1 products)
- PKM(17 products)
- PPAR(170 products)
- Phospholipase(85 products)
- ROR(47 products)
- Retinoid Receptor(18 products)
- SGK(10 products)
- Thioredoxin(12 products)
- Transferase(30 products)
- Transporter(43 products)
- UGT(4 products)
- Xanthine Oxidase (XO) Inhibitors(9 products)
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Found 9194 products of "Metabolism"
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Phytosterols
CAS:Phytosterols found in algae have anti-cancer activity and are used in the study of cardiovascular diseases and cancer.Purity:98%Color and Shape:Solidα-Glucosidase-IN-85
α-Glucosidase-IN-85 (Compound 8D1) functions as an inhibitor of α-Glucosidase, with an IC50 of 5.43 μM. This compound is useful for research related to type 2 diabetes.Color and Shape:Odour SolidO-Desmethyl apixaban
CAS:O-Desmethyl apixaban is a metabolite of Apixaban, a selective Factor Xa inhibitor with Ki of 0.08 nM in humans.Formula:C24H23N5O4Purity:98%Color and Shape:SolidMolecular weight:445.47β-1,3-Galactosyltransferase (CgtB)
CAS:CgtB enzyme, needed for GM1-like LOS SIAL, catalyzes galactose addition in biochemical studies.Color and Shape:Solidγ-Globulins from human blood
CAS:γ-Globulins, a protein fraction found in human blood, comprise a class of proteins with potent antibody activity that safeguards against bacterial and viralColor and Shape:Solid2-NP-AHD
CAS:2-NP-AHD, derived from AHD/nitrofuran metabolite, indicates illegal nitrofuran use.Formula:C10H8N4O4Color and Shape:SolidMolecular weight:248.20ERAP1-IN-3
ERAP1-IN-3 (compound 13) is a potent inhibitor of endoplasmic reticulum aminopeptidase 1 (ERAP1), with a pIC50 value of 8.6. ERAP1-IN-3 shows potential for research in cancer immunotherapy and autoimmune disease studies.Formula:C22H22N2O4SColor and Shape:SolidMolecular weight:410.49BRD8518
CAS:BRD8518, a PCSK9 inhibitor (EC50=0.23 μM), effectively lowers lipid levels by upregulating LDLR expression and enhancing the uptake of LDL. This compound is utilized in cardiovascular disease research.Formula:C33H32F3N3O5Color and Shape:SolidMolecular weight:607.62Cytochrome P450 reductase
CAS:Cytochrome P450 reductase, a NADPH-cytochrome reductase, facilitates an optimal conformation of aromatase for substrate binding [1].Color and Shape:SolidSaccharopine hydrochloride
Saccharopine hydrochloride, from lysine degradation, disrupts mitochondria and hinders development.Formula:C11H21ClN2O6Color and Shape:SolidMolecular weight:312.75DSPE-PEG2000-YIGSR
DSPE-PEG2000-YIGSR is a PEG compound composed of DSPE and the biomimetic peptide YIGSR. YIGSR interacts with the 67 kDa laminin-binding protein (LBP), enhancing the adhesion and proliferation of various cell types, including endothelial cells, fibroblasts, and smooth muscle cells. DSPE-PEG2000-YIGSR is applicable in drug delivery.Color and Shape:Odour SolidLodenafil carbonate
CAS:Lodenafil carbonate is a prodrug, orally used as a PDE5 inhibitor for ED treatment.Formula:C47H62N12O11S2Color and Shape:SolidMolecular weight:1035.21BIRM 271
CAS:BIRM 271 is a novel arachidonic acid release inhibitor that blocks leukotriene B4 and platelet-activating factor biosynthesis in human neutrophils.
Formula:C21H25N3OPurity:99.64%Color and Shape:SoildMolecular weight:335.44ATX inhibitor 7
CAS:ATX inhibitor 7 is a autotaxin inhibitor and shows good oral exposure.Formula:C21H22F3N7O2Color and Shape:SolidMolecular weight:461.449Adefovir diphosphate 2TEA
Adefovir diphosphate 2TEA,a metabolite of Adefovir, an oral reverse transcriptase inhibitor with antiviral activity against herpes, hepatitis B, and HIV.Formula:C20H43N7O7P2Purity:98.33%Color and Shape:SolidMolecular weight:555.55Sofosbuvir impurity C
CAS:Sofosbuvir impurity C, a less active byproduct, inhibits HCV RNA replication and exhibits strong anti-HCV effects.Formula:C22H29FN3O9PPurity:98%Color and Shape:SolidMolecular weight:529.45RORγ allosteric probe-1
CAS:RORγ Allosteric Probe-1 (Compound 12h), with excitation and emission wavelengths of 490/524 nm respectively, serves as an allosteric fluorescent probe for investigating RORγ allosteric inhibitors and the function of RORγ [1].Formula:C50H37ClF3N5O11SColor and Shape:SolidMolecular weight:1008.37Z-Thioprolyl-Thiazolidine
CAS:Z-Thioprolyl-Thiazolidine is a potent, specific inhibitor of bovine brain prolyl endopeptidase, demonstrating an inhibition constant (K i value) of 0.36 nM [1].Formula:C15H18N2O3S2Color and Shape:SolidMolecular weight:338.451α, 25-Dihydroxy VD2-D6
CAS:1alpha, 25-Dihydroxy VD2-D6 is a deuterated form of vitamin D.Formula:C28H44O3Purity:98%Color and Shape:SolidMolecular weight:434.6818:1 DGS-NTA(Ni)
CAS:18:1 DGS-NTA(Ni) is a nickel-chelating lipid. It exhibits high affinity for histidine tags and can bind to the histidine tags on recombinant proteins. This compound is useful in the preparation of liposomes and nanomultilamellar vesicles (NMV), which are employed in studies of protein and peptide binding as well as for antigen delivery.Formula:C53H94N2NiO15Color and Shape:SolidMolecular weight:1058.012,5-Anhydro-D-glucitol-1,6-diphosphate
CAS:2,5-Anhydro-D-glucitol-1,6-diphosphate mildly stimulates yeast Pyruvate Kinase; it's an analogue of a potent activator.Formula:C6H14O11P2Color and Shape:SolidMolecular weight:324.12Methyl 3,4,5-trimethoxy-2-(2-(nicotinamido)benzamido)benzoate
CAS:Preterramide C is a fungal metabolite that has been found inA.Formula:C24H23N3O7Color and Shape:SolidMolecular weight:465.46Fmoc-THR(GalNAc(Ac)3-α-D)-OH
CAS:ZINC77292789 (Fmoc-Thr[GalNAc(Ac)3-α-D]-OH) is a reagent for the preparation of a synthetic MUC1 Glycopeptide Bearing βGalNAc-Thr as a Tn antigen isomer whichFormula:C33H38N2O13Purity:99.24%Color and Shape:SolidMolecular weight:670.66Resveratrol-3-O-sulfate sodium
CAS:Resveratrol-3-O-sulfate reduces IL-1α/β, IL-6, TNF-α in LPS-stimulated U-937 cells, inhibits Caco-2 cell growth, induces apoptosis, and binds mitoNEET.Formula:C14H11NaO6SColor and Shape:SolidMolecular weight:330.29Cortisol sulfate
CAS:Cortisol sulfate (Cortisol 21-sulfate) is a metabolite of Cortisol . Cortisol sulfate is a specific ligand for intracellular transcortin [1] [2] [3] .Formula:C21H30O8SColor and Shape:SolidMolecular weight:442.52Galactosylhydroxylysine
CAS:Galactosylhydroxylysine, a bone collagen breakdown product, is released during bone resorption and excreted in urine.Formula:C12H24N2O8Color and Shape:SolidMolecular weight:324.33Lurasidone Metabolite 14283 hydrochloride
CAS:Lurasidone Metabolite 14283 hydrochloride is a major active metabolite of Lurasidone.Formula:C28H37ClN4O3SPurity:98%Color and Shape:SolidMolecular weight:545.143-HIB
CAS:3-HIB is a paracrine regulator of transendothelial fatty acid transport.Formula:C4H7NaO3Color and Shape:SolidMolecular weight:126.09ACAT-IN-6
CAS:ACAT-IN-6, from EP1236468A1 example 200, is a potent ACAT inhibitor that blocks NF-κB transcription.Formula:C31H47N3O5SColor and Shape:SolidMolecular weight:573.79Hydroxy bosentan
CAS:Hydroxy bosentan (Ro 48-5033), a Bosentan metabolite, is liver-processed with 10-20% of its activity.Formula:C27H29N5O7SPurity:98%Color and Shape:SolidMolecular weight:567.61[(3R)-3-Hydroxydodecanoyl]-L-carnitine
CAS:[(3R)-3-Hydroxydodecanoyl]-L-carnitine is an endogenous metabolite[1].Formula:C19H37NO5Color and Shape:SolidMolecular weight:359.50Tuftsin diacetate
CAS:Tuftsin diacetate, Thr-Lys-Pro-Arg, activates macrophages/microglia; it's in immunoglobulin G's Fc and boosts immunity.Formula:C25H48N8O10Purity:98%Color and Shape:SolidMolecular weight:620.71-Methylhistamine
CAS:2-(1-Methyl-1H-imidazol-4-yl)ethan-1-amine is a histamine metabolite.Formula:C6H11N3Purity:98%Color and Shape:SolidMolecular weight:125.1716C14-490
CAS:C14-490 is an ionizable cationic lipid (pKa= 5.94) utilized in the synthesis of lipid nanoparticles (LNPs). These LNPs serve as a platform for subsequent gene editing studies in hematopoietic stem cells (HSCs) in utero. C14-490 LNPs encapsulate SpCas9 mRNA and TTR sgRNA, employing an optimized B5 formulation parameter, and are further enhanced by the surface attachment of CD45 antibody F(ab’)2 fragments to create Systemically Targeted Editing Mechanism LNPs (STEM LNPs).Formula:C86H177N5O7Color and Shape:SolidMolecular weight:1393.35Ophiobolin A
CAS:Ophiobolin A: Fungal metabolite, phytotoxin, inhibits calmodulin-activated phosphodiesterase (IC50: 9μM), with antimicrobial and anticancer properties.Formula:C25H36O4Purity:98%Color and Shape:SolidMolecular weight:400.559Neoechinulin C
CAS:Neoechinulin C, a neuroprotective indolediketopiperazine, guards neurons against paraquat in Parkinson's.Formula:C24H27N3O2Color and Shape:SolidMolecular weight:389.49Benzoyl coenzyme A sodium
Benzoyl coenzyme A (sodium) is the sodium salt form of Benzoyl coenzyme A. It is a derivative of coenzyme A (CoA), where the thiol group of CoA is linked to a benzoyl group. This compound serves as a substrate in acyl transfer reactions, playing a role in catalysis. Benzoyl coenzyme A (sodium) is a versatile metabolic intermediate used in studies exploring enzyme substrate specificity, metabolic regulation, and drug metabolism.Formula:C28H39N7NaO17P3SColor and Shape:SolidMolecular weight:893.12337Arginase
CAS:Arginase (L-Arginine amidinase) is a key hydrolytic enzyme in the urea cycle, which hydrolyzes L-arginine into urea and L-ornithine.Color and Shape:SolidDSPE-PEG1000-pPB
DSPE-PEG1000-pPB is a PEG compound consisting of DSPE and a cyclic oligopeptide (pPB). The pPB component exhibits a strong binding affinity to PDGFRβ, which is overexpressed in activated hepatic stellate cells (HSC). DSPE-PEG1000-pPB is applicable for drug delivery.Color and Shape:Odour SolidCoprosterol
CAS:Coprosterol is a stanol formed from the biohydrogenation of cholesterol as a biomarker for the presence of human faecal matter in the environment.Formula:C27H48OColor and Shape:SolidMolecular weight:388.67Doxorubicinone
CAS:Adriamycin Aglycone, also known as Doxorubicinone, is an oncolytic agent. It is a metabolite of Doxorubicin which binds to the DNA minor-groove.Formula:C21H18O9Color and Shape:SolidMolecular weight:414.36CE(20:5(5Z,8Z,11Z,14Z,17Z)
CAS:CE(20:5(5Z,8Z,11Z,14Z,17Z) is an endogenous metabolite.Formula:C47H74O2Purity:98%Color and Shape:SolidMolecular weight:671.09XW-032
XW-032 is an apo-IDO1 inhibitor with an IC50 of 21 nM. In the CT26 syngeneic mouse model, XW-032 demonstrates significant in vivo antitumor efficacy with a TGI of 63%, showing potential for cancer research applications.Color and Shape:Odour Solidm-Tyramine
CAS:m-Tyramine has effects on the adrenergic and dopaminergic receptor.m-Tyramine is an endogenous trace amine neuromodulator.
Formula:C8H11NOPurity:98%Color and Shape:SolidMolecular weight:137.18CAIX Inhibitor S4
CAS:CAIX Inhibitor S4 (S4) is an effective inhibitor of carbonic anhydrase IX/XII with a Ki of 7 nM and 2 nM, respectively.
Formula:C15H17N3O4SPurity:99.07%Color and Shape:SolidMolecular weight:335.38m-PEG8-DSPE
m-PEG8-DSPE is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules.Formula:C59H116NO17PPurity:98%Color and Shape:SolidMolecular weight:1142.52(S)-Salsolidine
CAS:(S)-Salsolidine is a MAO inhibitor with Ki 63μM; its R enantiomer is more effective, Ki 26μM.Formula:C12H17NO2Color and Shape:SolidMolecular weight:207.27Cvs 738
CAS:Cvs 738 is the desmethyl form of CVS 1123, an orally bioavailable inhibitor of thrombin.Formula:C23H40N6O6Color and Shape:SolidMolecular weight:496.6Trimetazidine-N-oxide
CAS:Trimetazidine-N-oxide, main active metabolite of Trimetazidine, blocks 3-ketoyl CoA thiolase (IC50: 75nM) and has multiple protective properties.Formula:C14H22N2O4Purity:98%Color and Shape:SolidMolecular weight:282.34CAY10434
CAS:CAY10434, a potent CYP4A hydroxylase inhibitor, has an IC50 of 8.8 nM and boosts angiotensin II contraction, Emax 6764 mg.Formula:C17H25N3OPurity:99.85%Color and Shape:SolidMolecular weight:287.4
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