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Metabolism

Metabolism

Metabolism inhibitors are compounds that interfere with metabolic pathways, altering the production and utilization of energy within cells. These inhibitors are used to study the regulation of metabolism, the role of metabolic pathways in diseases like cancer and diabetes, and to develop new therapeutic strategies. Metabolism inhibitors can target various enzymes and processes involved in glycolysis, fatty acid oxidation, and other metabolic functions. At CymitQuimica, we offer a wide range of high-quality metabolism inhibitors to support your research in biochemistry, metabolic disorders, and drug development.

Subcategories of "Metabolism"

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Found 9258 products of "Metabolism"

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  • Inosine 5′-diphosphate sodium

    CAS:
    Inosine 5'-diphosphate sodium, a purine ribonucleoside diphosphate with inosine as its nucleobase, plays a role in intracellular energy metabolism and signal transduction processes.
    Formula:C10H13N4Na3O12P2
    Color and Shape:Solid
    Molecular weight:512.15
  • Nampt-IN-14

    CAS:
    Nampt-IN-14 (example 3) is an effective NAMPT inhibitor with an IC50 of 0.2 nM, suited for use in the synthesis of antibody-drug conjugates (ADCs).
    Formula:C33H35N7O2
    Color and Shape:Solid
    Molecular weight:561.68
  • (R,R)-BMS-986397

    CAS:
    (R,R)-BMS-986397 is a CK1α degrader with a DC50 ranging from 0.1 to 0.5 pM. This compound is applicable in leukemia research.
    Formula:C21H16ClF3N4O4
    Color and Shape:Solid
    Molecular weight:480.82
  • Ranosidenib

    CAS:
    Ranolisib is an isocitrate dehydrogenase (IDH) inhibitor known for its antitumor activity.
    Formula:C15H16F9N5O
    Color and Shape:Solid
    Molecular weight:453.31
  • SGK1-IN-3


    SGK1-IN-3: Potent oral inhibitor of SGK1, may target osteoarthritis.
    Formula:C23H20Cl2N6O3S
    Color and Shape:Solid
    Molecular weight:531.41
  • Nampt-IN-15

    CAS:
    Nampt-IN-15 (Example 3) is a Nampt inhibitor that exhibits cytotoxic effects on various cell lines, including BxPC-3, HepG2, L540cy, and MOLM-13. The respective IC50 values for these cell lines are 38.5 nM, 8 nM, 8.5 nM, and 7 nM.
    Formula:C24H30N4O2
    Color and Shape:Solid
    Molecular weight:406.52
  • RORγt inverse agonist 32

    CAS:
    RORγt inverse agonist 32 (compound b14) exhibits oral activity and can be utilized in inflammatory research studies.
    Formula:C24H28F3NO5S
    Color and Shape:Solid
    Molecular weight:499.54
  • CYP1B1-IN-2


    CYP1B1-IN-2 (compound 9j) is a highly potent and selective inhibitor of CYP1B1, a cytochrome P450 enzyme. It exhibits an IC50 value of 0.52 nM [1].
    Formula:C20H11F3O2
    Color and Shape:Solid
    Molecular weight:340.3
  • hMAO-B/MB-COMT-IN-2


    Dual inhibitor hMAO-B/MB-COMT-IN-2 targets hMAO-B (IC50: 4.27μM) & MB-COMT (IC50: 2.69μM), aids in neurodegenerative research.
    Formula:C17H18N2O3
    Color and Shape:Solid
    Molecular weight:298.34
  • NTPDase-IN-2

    CAS:
    NTPDase-IN-2 inhibits h-NTPDase-2/-8 (IC50: 0.04, 2.27 µM), non-competitive for h-NTPDase-1/-2 (Km: 74 µM); useful in cancer, immune, bacterial research.
    Formula:C24H20FN3OS2
    Color and Shape:Solid
    Molecular weight:449.56
  • ABT-046

    CAS:
    ABT-046 is an orally active, selective, and highly efficient Diacylglycerol Acyltransferase 1 (DGAT-1) inhibitor that can be used in metabolic disease research.
    Formula:C20H22N4O2
    Purity:98.13%
    Color and Shape:Solid
    Molecular weight:350.41
  • EGFR/VEGFR2-IN-2


    EGFR/VEGFR2-IN-2 (compound 4b) serves as a dual inhibitor of VEGFR-2 and EGFR.
    Formula:C24H15FO3
    Color and Shape:Solid
    Molecular weight:370.37
  • COTC

    CAS:
    COTC is an anticancer bacterial metabolite; inhibits glyoxalase with GSH, halts HeLa cell growth, and fights tumor in Ehrlich murine model.
    Formula:C11H14O6
    Color and Shape:Solid
    Molecular weight:242.23
  • Cilazapril HCl

    CAS:
    Cilazapril, also known as Ro 31 2848, is a potent ACE inhibitor used for hypertension.
    Formula:C22H32ClN3O5
    Color and Shape:Solid
    Molecular weight:453.96
  • Monometacrine

    CAS:
    Monometacrine, a cholesterol esterase inhibitor, exhibits antidepressant effects [1].
    Formula:C19H24N2
    Molecular weight:280.41
  • DRX-065

    CAS:
    DRX-065, a deuterated R-enantiomer of pioglitazone, treats NASH without PPARγ weight gain issues.
    Formula:C19H20N2O3S
    Molecular weight:357.45
  • Carbonic anhydrase inhibitor 2

    CAS:
    Compound 7c inhibits carbonic anhydrase II, lowering intraocular pressure in glaucomatous rabbits.
    Formula:C12H16N4O6S
    Color and Shape:Solid
    Molecular weight:344.34
  • DH376

    CAS:
    DH376 inhibits DAGLα in a time and dose dependent manner in mouse brain. DH376 shows picomolar activity.
    Formula:C31H28F2N4O3
    Color and Shape:Solid
    Molecular weight:542.58
  • Tacrolimus anhydrous 8-epimer

    CAS:
    Tacrolimus anhydrous 8-epimer, an immunosuppressive l-pipecolic acid macrolide, blocks T cell growth by hindering IL-2.
    Formula:C44H69NO12
    Color and Shape:Solid
    Molecular weight:804.02
  • IDO antagonist-1

    CAS:
    <p>IDO antagonist-1 (compound 163), an IDO antagonist, effectively inhibits the growth of pancreatic adenocarcinoma cells in C57BL/6 mice [1].</p>
    Formula:C39H53N7O5
    Color and Shape:Solid
    Molecular weight:699.88