Autophagy
Autophagy inhibitors target the cellular process of autophagy, which involves the degradation and recycling of cellular components through lysosomes. Autophagy is a critical mechanism for maintaining cellular homeostasis, but its dysregulation is implicated in various diseases, including cancer, neurodegeneration, and infections. Inhibitors of autophagy can block this process, making them valuable tools for studying the role of autophagy in disease and developing therapeutic strategies. At CymitQuimica, we offer autophagy inhibitors to support your research in cell biology, oncology, and neurodegenerative diseases.
Found 1424 products of "Autophagy"
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Tricyclic cytosine tC
CAS:<p>Tricyclic cytosine (tC) is a fluorescent analog of cytosine designed for RNA imaging within live cells, facilitating the study of RNA synthesis, degradation,</p>Formula:C15H15N3O5SColor and Shape:SolidMolecular weight:349.36PDEδ autophagic degrader 1
<p>PDEδ autophagic degrader 1 (compound 12c) is an autophagosome-tethering compound (ATTEC) and a potent autophagic degrader of PDEδ. This compound effectively reduces PDEδ protein levels through lysosome-mediated autophagy without affecting PDEδ mRNA expression. Additionally, PDEδ autophagic degrader 1 inhibits the growth of KRAS mutant pancreatic cancer cells.</p>Formula:C41H42Br2IN7O5Molecular weight:997.06589Zn-DPA-maytansinoid conjugate 1
<p>Zn-DPA-maytansinoid 1 targets checkpoints, shrinks tumors, and heats TME.</p>Formula:C115H145ClN18O31S2Zn2Color and Shape:SolidMolecular weight:2505.83CXCR4 antagonist 1
CAS:<p>CXCR4 antagonist 1 is a potent inhibitor of the CXCR4 receptor, with notable anti-HIV activity.</p>Formula:C27H43N7Color and Shape:SolidMolecular weight:465.69(S)-Thalidomide-piperazine-pyrimidine-piperazine-C2-OH
<p>(S)-Thalidomide-piperazine-pyrimidine-piperazine-C2-OH is a conjugate of an E3 ligase ligand and a linker (E3LigaseLigand-Linker Conjugates), consisting of Thalidomide and the corresponding Linker. It functions as a Cereblon ligand to recruit the CRBN protein and serves as a crucial intermediate for synthesizing complete PROTAC molecules.</p>Formula:C27H32N8O5Molecular weight:548.24957p62-ZZ Ligand-Linker Conjugate 1
CAS:<p>p62-ZZ Ligand-Linker Conjugate 1 is a conjugate of the p62-ZZ domain ligand and linker. This compound is utilized in the synthesis of AUTOTACVinclozolinM2-2204.</p>Formula:C31H42N2O6Color and Shape:SolidMolecular weight:538.68(1R,5S)-Thalidomide-3,8-diazabicyclo[3.2.1]octane-(1R,4r)-cyclohexane-NH-Boc
<p>(1R,5S)-Thalidomide-3,8-diazabicyclo[3.2.1]octane-(1R,4r)-cyclohexane-NH-Boc is a conjugate of an E3 ligase ligand and linker (E3LigaseLigand-Linker Conjugates), composed of Thalidomide and the corresponding linker. This compound serves as a Cereblon ligand to recruit CRBN protein and acts as a crucial intermediate in the synthesis of complete PROTAC molecules.</p>Formula:C31H41N5O6Molecular weight:579.30568EthD-III
<p>EthD-III: red fluorescent nucleic acid probe; stains dead cells; binds to DNA in cells with damaged membranes; Ex/Em=530/645 nm.</p>Formula:C51H62Cl5N9Color and Shape:SolidMolecular weight:978.36Cy5.5-SE (DIPEA)
<p>Cy5.5-SE DIPEA is a water-soluble CY dye often used for labeling proteins and antibodies, with simple mixing for conjugation. Store protected from light.</p>Formula:C53H66N4O16S4Color and Shape:SolidMolecular weight:1143.37HDAC-IN-62
<p>HDAC-IN-62 (Compound 5), an HDAC inhibitor, exhibits IC50 values of 0.78, 1.0, and 1.2 μM for HDAC6, HDAC8, and HDAC11, respectively.</p>Formula:C15H14N2O3SPurity:98%Color and Shape:SolidMolecular weight:302.35Beclin1-Bcl-2 interaction inhibitor 1
<p>Beclin1-Bcl-2 Interaction Inhibitor 1 effectively disrupts the binding of Beclin 1 to Bcl-2, and is utilized in cancer and neurodegeneration research [1].</p>Color and Shape:Odour SolidRCP168
<p>RCP168 is a highly selective and potent CXCR4 receptor antagonist with an IC50 of 5 nM. It exhibits superior capacity to inhibit HIV-1 (Human Immunodeficiency Virus type 1) from entering host cells via the CXCR4 receptor compared to natural chemokines. RCP168 suppresses HIV-1 infection by blocking viral binding sites or inducing receptor internalization. It can be utilized in research to study interactions between the CXCR4 receptor and other chemokine receptors.</p>Formula:C365H585N105O95S5Molecular weight:8119.27766Episilvestrol
CAS:<p>Episilvestrol is a derivative of silvestrol with eIF4A-targeted antitumor properties, found in Aglaia silvestris fruits and twigs.</p>Formula:C34H38O13Purity:98%Color and Shape:SolidMolecular weight:654.66Corydalmine hydrochloride
CAS:<p>Corydalmine hydrochloride: antifungal, oral analgesic, soothes neuropathic pain by blocking NF-κB/CXCL1/CXCR2.</p>Formula:C20H24ClNO4Color and Shape:SolidMolecular weight:377.86AUTAC2
CAS:<p>AUTAC2, an FKBP12-targeting AUTAC, contains FBnG and SLF, with SLF non-covalently binding FKBP12.</p>Formula:C61H81FN10O14SColor and Shape:SolidMolecular weight:1229.42CXCL8 (54-72)
<p>CXCL8 (54-72) is a C-terminal peptide segment of the chemokine CXCL8. This peptide features a long, highly positively charged C-terminal region that interacts with the negative charges on glycosaminoglycans (GAG) to facilitate binding. CXCL8 (54-72) inhibits neutrophil adhesion and migration, as well as adhesion to endothelial cells. It is useful in studying the role of chemokines in inflammatory responses.</p>Formula:C107H173N33O30Molecular weight:2400.30261CXCR4-IN-3
<p>CXCR4-IN-3 (compound XVI) is an orally active inhibitor targeting the inflammation-related receptor CXCR4, with an IC50 of 3.2 nM. It exhibits potent anti-chemotactic effects, with an inhibition rate of 79.19±2.33%. Additionally, CXCR4-IN-3 possesses anti-inflammatory properties and can be utilized in research on IBD (inflammatory bowel disease).</p>CCR7 antagonist 1
<p>CCR7 antagonist1 (30c) functions as a dual antagonist, targeting CXCR2 with an IC50 of 11.02 μM and CCR7 with an IC50 of 0.43 μM.</p>Formula:C13H22N6OSMolecular weight:310.15758(1R,4R)-Thalidomide-2,5-diazabicyclo[2.2.1]heptane-(1R,4r)-cyclohexane-NH-Boc
<p>(1R,4R)-Thalidomide-2,5-diazabicyclo[2.2.1]heptane-(1R,4r)-cyclohexane-NH-Boc is a conjugate of an E3 ligase ligand and linker (E3LigaseLigand-Linker Conjugates), composed of Thalidomide and the corresponding linker. It acts as a Cereblon ligand, recruiting CRBN proteins, and serves as a crucial intermediate in the synthesis of complete PROTAC molecules.</p>Formula:C30H39N5O6Molecular weight:565.29003Autophagy/REV-ERB-IN-1
<p>Autophagy/REV-ERB-IN-1 is a dual inhibitor of autophagy and REV-ERB. It exhibits antitumor activity, with a CC50 value of 2.3 μM in BTB-474 cells.</p>Formula:C24H30F2N2Molecular weight:384.23771Antitumor agent-133
<p>Antitumor agent-133 (compound 4d) is a bis-santine derivative that demonstrates activity against Huh1 (IC50 = 17.13 μM) and Huh7 (IC50 = 8.27 μM). It induces autophagy and inhibits tumor growth by modulating the levels of the LC3BII, ATG5, and p62 proteins.</p>Formula:C27H24Br2N4O8Molecular weight:689.99609Bam 12P
CAS:<p>Bam 12P is a Pro-Met-enkephalin precursor that is isolated from the bovine adrenal medulla.</p>Formula:C62H97N21O16SPurity:98%Color and Shape:SolidMolecular weight:1424.64Ch55-O-C3-NH2
CAS:<p>Ch55-O-C3-NH2, also known as RAR ligand 1, is a ligand derived from the Ch55 compound that specifically targets RAR.</p>Formula:C27H35NO4Purity:98%Color and Shape:SolidMolecular weight:437.57Cyanine 5 Tyramide methyl indole
<p>Cyanine 5 Tyramide is a red dye used in HRP assays and nucleic acid hybridization. Store away from light.</p>Formula:C40H47N3O8S2Color and Shape:SolidMolecular weight:761.95N6-Isopentenyladenosine
CAS:<p>N6-Isopentenyladenosine, an end product of the mevalonate pathway, is an autophagy inhibitor with anti-melanoma activity.</p>Formula:C15H21N5O4Purity:97.13% - 99.69%Color and Shape:SolidMolecular weight:335.36(S)-Thalidomide-piperazine-pyrimidine-piperazine-C2-O-C2-OH
<p>(S)-Thalidomide-piperazine-pyrimidine-piperazine-C2-O-C2-OH is a conjugate combining an E3 ligase ligand with a linker (E3LigaseLigand-Linker Conjugates), composed of Thalidomide and the corresponding Linker. This compound functions as a Cereblon ligand, recruiting the CRBN protein and serving as a crucial intermediate in the synthesis of complete PROTAC molecules.</p>Formula:C29H36N8O6Molecular weight:592.27578Olaparib-d5
CAS:<p>Olaparib D5 is a deuterium labeled Olaparib. Olaparib is a potent and oral inhibitor of PARP.</p>Formula:C24H23FN4O3Purity:98%Color and Shape:SolidMolecular weight:439.49Dexamethasone-d5
CAS:<p>Dexamethasone-d5 is a deuterated compound of Dexamethasone.</p>Formula:C22H24D5FO5Color and Shape:SolidMolecular weight:397.49Imatinib D4
CAS:<p>Imatinib D4 is a deuterium-labeled Imatinib. Imatinib is an orally bioavailable tyrosine kinases inhibitor that selectively inhibits BCR/ABL, PDGFR, v-Abl, and c-kit kinase activity.</p>Formula:C29H31N7OPurity:98%Color and Shape:SolidMolecular weight:497.63Bexarotene D4
CAS:<p>Bexarotene D4 is a deuterium-labeled Bexarotene (LGD1069). Bexarotene is a selective RXR agonist used in the treatment of cutaneous T-cell lymphoma.</p>Formula:C24H28O2Purity:98%Color and Shape:SolidMolecular weight:352.5Trimetazidine
CAS:<p>Trimetazidine is a antianginal agent that selectively inhibits the mitochondrial enzyme LC 3-KAT, thereby preventing β-oxidation of free fatty acids.</p>Formula:C14H22N2O3Purity:99.9%Color and Shape:Hite Or Off-White Crystalline PowderMolecular weight:266.34Binimetinib-13C-d3
<p>Binimetinib-13C-d3 (MEK162) is an isotopically labelled compound of Binimetinib.Binimetinib (ARRY-162) is a selective MEK1/2 inhibitor melanoma.</p>Formula:C17H15BrF2N4O3Color and Shape:SolidMolecular weight:445.24Pyrazinamide-d3
CAS:<p>Pyrazinamide-d3 is a deuterated compound of Pyrazinamide. Pyrazinamide has a CAS number of 98-96-4. Pyrazinamide, an antimycobacterial, is utilized therapeutically as an antitubercular agent, which is a synthetic pyrazinoic acid amide derivative.</p>Formula:C5D3H2N3OColor and Shape:SolidMolecular weight:126.13Omeprazole-d3
CAS:<p>Omeprazole D3 is deuterium labeled Omeprazole. Omeprazole is a proton pump inhibitor (PPI)</p>Formula:C17H19N3O3SPurity:98%Color and Shape:SolidMolecular weight:348.44LG100268
CAS:<p>LG100268 is a selective, and oral RXR agonist，inducing transcriptional activation in adipocytes; inhibits keratin 17 increases PD-L1 expression.</p>Formula:C24H29NO2Purity:99.83%Color and Shape:SolidMolecular weight:363.49Enzalutamide-d3
CAS:<p>Enzalutamide D3 is a deuterium labeled Enzalutamide . Enzalutamide is an androgen receptor (AR) antagonist with an IC50 of 36 nM in LNCaP prostate cells.</p>Formula:C21H16F4N4O2SColor and Shape:SolidMolecular weight:467.45TRAF6 peptide TFA
<p>TRAF6 peptide TFA, a specific inhibitor of the TRAF6-p62 interaction, significantly inhibits NGF-dependent ubiquitination of TrkA.</p>Formula:C145H238N34O44·xC2HF3O2Purity:98%Color and Shape:SolidMolecular weight:3161.64 (free acid)Isoniazid-d4
CAS:<p>Isoniazid-d4 is a deuterium isotope marker for Isoniazid.Isoniazid is a prodrug that must be activated by the bacterial peroxidase KatG, and is bactericidal.</p>Formula:C6H3D4N3OColor and Shape:SolidMolecular weight:141.16Rapalink-1
CAS:<p>Rapalink-1 is an mTOR inhibitor that inhibits the mTORC1-4E-BP1 pathway in mice.</p>Formula:C91H138N12O24Purity:98%Color and Shape:SolidMolecular weight:1784.14Erlotinib-d6 hydrochloride
CAS:<p>Erlotinib Hydrochloride inhibits purified EGFR kinase with an IC50 of 2 nM. Erlotinib D6 hydrochloride a deuterium labeled Erlotinib Hydrochloride.</p>Formula:C22H24ClN3O4Purity:98%Color and Shape:SolidMolecular weight:435.93Ponatinib-d8
CAS:<p>Ponatinib D8 is a deuterium-enriched, oral multi-kinase inhibitor (Abl, PDGFRα, VEGFR2, FGFR1, Src; IC50s: 0.37-5.4 nM).</p>Formula:C29H27F3N6OPurity:98%Color and Shape:SolidMolecular weight:540.61Anti-LRRK2 Antibody (1C773)
<p>Anti-LRRK2 Antibody (1C773) is an antibody targeting LRRK2. Anti-LRRK2 Antibody (1C773) can be used in ELISA, IHC.</p>Color and Shape:Odour LiquidEzetimibe-d4
CAS:<p>Ezetimibe D4, a deuterium-labeled variant of Ezetimibe, functions as an inhibitor of Niemann-Pick C1-like1 (NPC1L1) and is recognized for its potent activation</p>Formula:C24H21F2NO3Purity:98%Color and Shape:White SolidMolecular weight:413.45Tetrahydrocurcumin D6
CAS:<p>Tetrahydrocurcumin D6 is a deuterium labeled Tetrahydrocurcumin. Tetrahydrocurcumin displays inhibitory activity for CYP2C9 and CYP3A4.</p>Formula:C21H24O6Purity:98%Color and Shape:SolidMolecular weight:378.45Manzamine A
CAS:<p>Manzamine A, from marine sponges, blocks GSK-3, halts cancer growth, prevents bacterial infections, and reduces tau phosphorylation.</p>Formula:C36H44N4OPurity:98%Color and Shape:SolidMolecular weight:548.775PS372424 hydrochloride
CAS:<p>PS372424 hydrochloride,CXCR3 agonist. Anti-inflammatory. Inhibits T-cell migration.</p>Formula:C33H45ClN6O4Purity:95.03%Color and Shape:SolidMolecular weight:625.2Idelalisib D5
CAS:<p>Idelalisib D5, a version of Idelalisib marked with deuterium, is an orally bioavailable and highly selective inhibitor of p110δ.</p>Formula:C22H18FN7OPurity:98%Color and Shape:SolidMolecular weight:420.45Ladarixin
CAS:<p>Ladarixin (DF 2156A free base) is an orally active, non-competitive CXCR1/CXCR2 allosteric inhibitor that suppresses AKT, NF-κB, and angiogenesis.</p>Formula:C11H12F3NO6S2Purity:99.36%Color and Shape:SolidMolecular weight:375.34Rosuvastatin D3 Sodium
CAS:<p>Rosuvastatin D3 Sodium is deuterium labeled Rosuvastatin, which is a competitive HMG-CoA reductase inhibitor(IC50 of 11 nM).</p>Formula:C22H24D3FN3NaO6SPurity:98%Color and Shape:SolidMolecular weight:506.54Cilengitide TFA
CAS:<p>Cilengitide, αvβ3/αvβ5 inhibitor, IC50: 4.1/79 nM in vitro. 10x selectivity vs. gpIIbIIIa. Phase 2.</p>Formula:C29H41F3N8O9Color and Shape:SolidMolecular weight:702.68Saquinavir mesylate
CAS:<p>Saquinavir mesylate (Ro 31-8959/003) is an Inhibitor of HIV Proteaseused in antiretroviral therapy</p>Formula:C39H54N6O8SPurity:99.19%Color and Shape:White Or Pale Yellow PowderMolecular weight:766.9GW406108X
CAS:<p>GW406108X is a Kif15 and ULK1 inhibitor; IC50: 0.82 µM (ATPase), pIC50: 6.37; blocks autophagy.</p>Formula:C20H11Cl2NO4Purity:98%Color and Shape:SolidMolecular weight:400.21R1487 Hydrochloride
CAS:<p>R1487 Hydrochloride (R1487 (Hydrochloride)) is an orally bioavailable and highly selective inhibitors of p38α.</p>Formula:C19H19ClF2N4O3Purity:99.42%Color and Shape:SolidMolecular weight:424.83Gemcitabine elaidate
CAS:<p>Gemcitabine elaidate (CP-4126), is a lipophilic, unsaturated fatty acid ester derivative of gemcitabine (dFdC), an antimetabolite deoxynucleoside analogue, with</p>Formula:C27H43F2N3O5Color and Shape:SolidMolecular weight:527.64Curcumin-d6
CAS:<p>Curcumin D6 (difluoroformylmethane D6) is deuterium-labeled curcumin (Turmeric yellow). Curcumin (Turmeric yellow) is a natural phenolic compound with various pharmacological effects, including anti-inflammatory, antioxidant, anti-proliferative and anti-a</p>Formula:C21H20O6Purity:98%Color and Shape:SolidMolecular weight:374.422Heparin Lithium
CAS:<p>Heparin Lithium salt is an anticoagulant that reversibly binds to ATIII and enhances its inhibitory effect on coagulation factor(thrombin and factor Xa).</p>Formula:C14H25NO20S3Color and Shape:SolidMolecular weight:623.01321Aliskiren
CAS:<p>Aliskiren (CGP 60536) is a renin inhibitor (IC50: 1.5 nM) with antihypertensive activity and is used in the treatment of various cardiovascular diseases.</p>Formula:C30H53N3O6Purity:97.02%Color and Shape:SolidMolecular weight:551.76THZ-P1-2
CAS:<p>THZ-P1-2 is a PI5P4K inhibitor with anti-leukemic activity and can be used in the study of leukemia.</p>Formula:C31H29N7O2Color and Shape:SolidMolecular weight:531.61Br-DAPI
CAS:<p>IST5-002 (N6-Benzyladenosine-5'-phosphate) is a Stat5a/b inhibitor with anticancer activity and is used in cancer research.</p>Formula:C16H14BrN5Purity:100%Color and Shape:SolidMolecular weight:356.22OR-1855
CAS:<p>OR-1855 is an active Levosimendan metabolite, has effect on human myometrial contractility.</p>Formula:C11H13N3OPurity:98%Color and Shape:Pale Yellow SolidMolecular weight:203.24Rapamycin-d3
CAS:<p>Rapamycin-d3 is the deuterium labeled Rapamycin. Rapamycin is a potent and specific inhibitor of mTOR(IC50 of 0.1 nM in HEK293 cells).</p>Formula:C51H79NO13Purity:98%Color and Shape:SolidMolecular weight:917.19V-9302 hydrochloride
CAS:<p>V-9302 hydrochloride is a competitive transmembrane glutamine flux antagonist that selectively targets the amino acid transporter ASCT2/SLC1A5.</p>Formula:C34H39ClN2O4Purity:97.31%Color and Shape:SolidMolecular weight:575.14IKK 16 hydrochloride
CAS:<p>IKK 16 hydrochloride, a potent IKK1/2 and LRRK2 inhibitor, IC50s: 40-200 nM and 50 nM respectively.</p>Formula:C28H30ClN5OSColor and Shape:SolidMolecular weight:520.09ACT-1004-1239
CAS:<p>ACT-1004-1239 is a CXCR7 antagonist with immunomodulatory and myelination-promoting effects, used for research on inflammatory demyelinating diseases.</p>Formula:C27H28F2N6O3Purity:98.31%Color and Shape:SolidMolecular weight:522.55ATI-2341
CAS:<p>ATI-2341, pepducin targeting the CXCR4, is an allosteric agonist activating the Gi to promote inhibition of cAMP production and induce calcium mobilization.</p>Formula:C104H178N26O25S2Color and Shape:SolidMolecular weight:2256.82CXCR2 antagonist 8
CAS:<p>CXCR2 antagonist 8 is a selective CXCR2 antagonist, which can be used for the treatment and prevention of insulin resistance.</p>Formula:C14H13N3O5Color and Shape:SolidMolecular weight:303.27Motixafortide
CAS:<p>Motixafortide (BKT140 4-fluorobenzoyl) is an antagonist of CXCR4 (IC50: 1 nM).</p>Formula:C97H144FN33O19S2Purity:98%Color and Shape:SolidMolecular weight:2159.52Cediranib maleate
CAS:<p>Cediranib maleate (AZD2171 maleate) is a VEGFR2 inhibitor that inhibits Flt1, KDR, Flt4, PDGFRα, PDGFRβ, c-Kit.</p>Formula:C29H31FN4O7Color and Shape:SolidMolecular weight:566.58Resveratrol analog 1
CAS:<p>Resveratrol analog 1 is a natural product analog of resveratrol, which has more significant anti-leukemic activity than resveratrol.</p>Formula:C14H11FO2Purity:98.42%Color and Shape:SolidMolecular weight:230.23Megestrol Acetate-d3
CAS:<p>Megestrol Acetate-d3 is a deuterated compound of Megestrol Acetate. Megestrol Acetate has a CAS number of 595-33-5. Megestrol acetate is a progestogen with actions and uses similar to those of the progestogens in general. Megestrol acetate also has anti-androgenic properties. It is given by mouth in the palliative treatment or as an adjunct to other therapy in endometrial carcinoma and in breast cancer. Megestrol acetate has been approved to treat anorexia and cachexia.</p>Formula:C24H29D3O4Color and Shape:SolidMolecular weight:387.53Rupatadine
CAS:<p>Rupatadine (UR-12592, rupatadine) is a potent and orally available dual antagonist of PAF and histamine H1 receptors ,allergic and anti-inflammatory.</p>Formula:C26H26ClN3Purity:99.87%Color and Shape:SolidMolecular weight:415.96Rosuvastatin Sodium
CAS:<p>Rosuvastatin Sodium: HMGCR inhibitor, blocks hERG (IC50: 11 nM, 195 nM), reduces hERG expression, hinders Hsp70-hERG interaction.</p>Formula:C22H27FN3NaO6SColor and Shape:SolidMolecular weight:503.52Metformin-d6 hydrochloride
CAS:<p>Metformin-d6 hydrochloride (Metformin-d6 hydrochloride) is a deuteride of Metformin, which can be used to study Metformin metabolism in vivo.</p>Formula:C4H12ClN5Purity:98.1%Color and Shape:SolidMolecular weight:171.66Nilotinib-d6
CAS:<p>Nilotinib D6 is a deuterium labeled Nilotinib which is an orally available inhibitor of Bcr-Abl tyrosine kinase ,and with antineoplastic activity.</p>Formula:C28H22F3N7OPurity:98%Color and Shape:SolidMolecular weight:535.55Peptide R TFA
<p>Peptide R (TFA) is a synthetic and specific CXCR4 antagonist. It demonstrates excellent tumor stroma remodeling capabilities and is applicable in research on solid tumors, such as glioblastoma.</p>Formula:C39H57N13O8S2·xC2HF3O2Color and Shape:SolidMolecular weight:900.08 (free base)LY2510924
CAS:<p>LY2510924 is an effective and selective CXCR4 antagonist. It blocks SDF-1 binding to CXCR4 (IC50: 0.079 nM).</p>Formula:C62H88N14O10Color and Shape:SolidMolecular weight:1189.45Afatinib D6
CAS:<p>Afatinib D6 (BIBW 2992 D6) is a deuterium-labeled Afatinib. Afatinib is an irreversible EGFR family inhibitor.</p>Formula:C24H25ClFN5O3Color and Shape:SolidMolecular weight:491.98Gefitinib-d8
CAS:<p>Gefitinib is an EGFR tyrosine kinase inhibitor, with IC50 of 2-37 nM in NR6wtEGFR cells. Gefitinib D8 is a deuterium labeled Gefitinib.</p>Formula:C22H24ClFN4O3Purity:98%Color and Shape:SolidMolecular weight:454.95Brivanib
CAS:<p>Brivanib (BMS-540215) is an ATP-competitive inhibitor against VEGFR2 with IC50 of 25 nM, moderate potency against VEGFR-1 and FGFR-1, but >240-fold against</p>Formula:C19H19FN4O3Purity:98.87%Color and Shape:SolidMolecular weight:370.38Silibinin-d3
<p>Silibinin-d3 is the deuterium-labelled compound of silibinin, used for isotope tracing. Silibinin inhibit cancer cell proliferation and migration.</p>Formula:C25H22O10Color and Shape:SolidMolecular weight:485.46Regorafenib-d3
CAS:<p>Regorafenib D3 is a deuterium labeled Regorafenib. Regorafenib is a multi-targeted receptor inhibitor of tyrosine kinase.</p>Formula:C21H15ClF4N4O3Purity:98%Color and Shape:SolidMolecular weight:485.83KN-93 hydrochloride
CAS:<p>KN-93 hydrochloride is a cell-permeable, reversible and competitive calmodulin-dependent kinase type II ( CaMKII ) inhibitor with a K i of 370 nM.</p>Formula:C26H30Cl2N2O4SColor and Shape:SolidMolecular weight:537.5Loperamide-d6 hydrochloride
CAS:<p>Loperamide D6 HCl: Deuterium-enriched opioid for diarrhea.</p>Formula:C29H34Cl2N2O2Purity:98%Color and Shape:SolidMolecular weight:519.54Pemetrexed disodium heptahydrate
CAS:<p>Pemetrexed disodium heptahydrate (LY231514) is an antifolate that inhibits TS, DHFR and GARFT, inhibits precursor purine and pyrimidine nucleotides.</p>Formula:C20H33N5Na2O13Purity:99.783%Color and Shape:SolidMolecular weight:597.49Levomepromazine
CAS:<p>Levomepromazine (Methotrimeprazine) is a Ca2+ release inducer with antiviral, anti-inflammatory, neuroprotective, sedative, and anti-nociceptive activities.</p>Formula:C19H24N2OSPurity:99.15%Color and Shape:SolidMolecular weight:328.47Ginkgolide K
CAS:<p>Ginkgolide K induces protective autophagy through the AMPK/mTOR/ULK1 signalling pathway. It possesses neuroprotective activity.</p>Formula:C20H22O9Purity:99.44% - 99.72%Color and Shape:SolidMolecular weight:406.38Ginsenoside F2
CAS:<p>Ginsenoside F2 halts breast CSCs growth, induces apoptosis via intrinsic pathway and impairs mitochondria.</p>Formula:C42H72O13Purity:99.04% - 99.3%Color and Shape:SolidMolecular weight:785.01Valproic Acid
CAS:<p>Valproic Acid (2-Propylpentanoic Acid) is a branched chain fatty acid which potentially enhances central GABAergic neurotransmission and inhibits Na+ channels.</p>Formula:C8H16O2Purity:97.78% - 99%Color and Shape:Colourless To Pale Yellow Liquid ViscousMolecular weight:144.21Momelotinib
CAS:<p>Momelotinib (LM-1149), an oral JAK1/2 inhibitor with IC50s 11/18 nM, blocks ATP binding, disrupting JAK-STAT pathway and reducing tumor growth.</p>Formula:C23H22N6O2Purity:97.47% - 99.56%Color and Shape:SolidMolecular weight:414.46TBHQ
CAS:<p>TBHQ (tert-Butylhydroquinone) is an antioxidant that induces an antioxidant response through the redox-sensitive transcription factor Nrf2.</p>Formula:C10H14O2Purity:99.17% - 99.53%Color and Shape:White Solid PowderMolecular weight:166.22Clematichinenoside AR
CAS:<p>Clematichinenoside AR is anti-inflammatory, immunosuppressive, and combats arthritis via PI3K/Akt and TNF-α pathways.</p>Formula:C82H134O43Purity:99.04% - 99.69%Color and Shape:SolidMolecular weight:1807.92Actein
CAS:<p>Actein stimulates bone formation, counters osteoporosis and oxidative damage, and may treat lipid disorders and cancer, inhibiting breast cancer cell growth.</p>Formula:C37H56O11Purity:≥98%Color and Shape:Brown PowderMolecular weight:676.83Selenomethionine
CAS:<p>DL-Selenomethionine (SeMet) is a selenium analog of methionine, substituting sulfur with selenium, and can replace methionine in proteins.</p>Formula:C5H11NO2SePurity:98% - 99.95%Color and Shape:Transparent Hexagonal Sheets Or Plates; Metallic Luster Of Crystals SolidMolecular weight:196.11Dimethyl fumarate
CAS:<p>Dimethyl fumarate (DMF) is an orally Nrf2 activator. Dimethyl fumarate has antimicrobial and anti-inflammatory activities. Cost-effective and quality-assured.</p>Formula:C6H8O4Purity:90.51% - >99.99%Color and Shape:White To Off-White Powder White Crystalline PowderMolecular weight:144.13Hoechst 33342
CAS:<p>Hoechst 33342 (bisBenzimide H 33342) is a benzimidazole fluorescent dye and a cell-permeable fluorescent DNA dye. High-Quality, Low-Cost!</p>Formula:C27H28N6OPurity:98.12% - 99.75%Color and Shape:Yellow-Green PowderMolecular weight:452.55ABT-751
CAS:<p>ABT-751 (E7010) has been investigated for the treatment of Lung Cancer, Non-Small Cell Lung Cancer, and Non-Small-Cell Lung Cancer.</p>Formula:C18H17N3O4SPurity:98.84% - 99.50%Color and Shape:SolidMolecular weight:371.41GNE0877
CAS:<p>GNE0877 (GNE 0877) is a highly effective and specific leucine-rich repeat kinase 2 (LRRK2) inhibitor (Ki: 0.7 nM).</p>Formula:C14H16F3N7Purity:98.01% - 99.97%Color and Shape:SolidMolecular weight:339.32Autophinib
CAS:<p>Autophinib is a potent autophagy inhibitor with a novel chemotype with IC50 values of 90 and 40 nM for autophagy in starvation induced autophagy assay and</p>Formula:C14H11ClN6O3Purity:99.25% - 99.41%Color and Shape:SolidMolecular weight:346.73Corynoxine
CAS:<p>Corynoxine is a tetracyclic oxindole alkaloid isolated from Uncaria macrophylla.</p>Formula:C22H28N2O4Purity:96.83% - 99.93%Color and Shape:SolidMolecular weight:384.47STO-609
CAS:<p>STO-609 inhibits CaM-KKα/KKβ (Ki: 80/15 ng/mL), is specific, cell-permeable, and targets Ca2+/calmodulin-dependent protein kinase kinase.</p>Formula:C19H10N2O3Purity:97.14% - 98.8%Color and Shape:SolidMolecular weight:314.29JMS-17-2 hydrochloride
CAS:<p>JMS-17-2 hydrochloride: potent CX3CR1 blocker, IC50 of 0.32 nM, hinders breast cancer metastasis.</p>Formula:C25H27Cl2N3OColor and Shape:SolidMolecular weight:456.41Brevilin A
CAS:<p>Brevilin A, a sesquiterpene from Centipeda minima, hinders JAK and blocks STAT3 (IC50=10.6μM), inducing apoptosis and autophagy in cancer cells.</p>Formula:C20H26O5Purity:99.97% - >99.99%Color and Shape:SolidMolecular weight:346.42Tempol
CAS:<p>Tempol (Tanol) is a superoxide scavenger. It has anti-inflammatory, neuroprotective and analgesic effects.</p>Formula:C9H18NO2Purity:97% - 99.74%Color and Shape:4-Hydroxy-Tempo Appears As Orange Flakes Solid FlakesMolecular weight:172.25CHIR-99021
CAS:<p>View and buy CHIR-99021 from TargetMol.CHIR-99021 is a GSK-3α/β inhibitor.Cited in 10 publications.</p>Formula:C22H18Cl2N8Purity:97.94% - ≥95%Color and Shape:SolidMolecular weight:465.34Bergapten
CAS:<p>Bergapten (5-Methoxypsoralen), a psoralen, inhibits cell replication.</p>Formula:C12H8O4Purity:99.48% - ≥95%Color and Shape:Needles From Alcohol; Soln In Sulfuric Acid Is Yellow-Gold Physical Description Grayish-White Micr°Crystalline Powder Or Yellow Fluffy Solid (Ntp 1992)Molecular weight:216.19Tanespimycin
CAS:<p>Tanespimycin (KOS 953) is an Hsp90 inhibitor (IC50=5 nM) and is selective. Tanespimycin depletes intracellular STK38/NDR1. High-Quality, Low-Cost!</p>Formula:C31H43N3O8Purity:99.07% - 99.83%Color and Shape:Dark Purple SolidMolecular weight:585.69IOWH-032
CAS:<p>IOWH-032 (IOWH032) , a synthetic CFTR inhibitor, has been investigated for the treatment of cholera, diarrhea, and secretory diarrhea.</p>Formula:C22H15Br2N3O4Purity:98.92% - ≥95%Color and Shape:SolidMolecular weight:545.18Sinomenine
CAS:<p>Sinomenine (Kukoline) is a pure alkaloid isolated from the Sinomenium acutum, is utilized in the treatment of rheumatism and arthritis.</p>Formula:C19H23NO4Purity:99.02% - 99.73%Color and Shape:White PowderMolecular weight:329.39Dantrolene
CAS:<p>Dantrolene is a postsynaptic muscle relaxant by inhibiting Ca2+ ions release from sarcoplasmic reticulum stores by antagonizing ryanodine receptors.</p>Formula:C14H10N4O5Purity:99.97%Color and Shape:Crystals From Aq DimethylformamideMolecular weight:314.25Isorhapontigenin
CAS:<p>Isorhapontigenin: a methoxylated stilbenoid isomer of rhapontigenin, similar to resveratrol, present in Gnetum spp. and Aiphanes aculeata seeds.</p>Formula:C15H14O4Purity:98.49% - 99.85%Color and Shape:Off White Crystals PowerMolecular weight:258.27Pinocembrin
CAS:<p>Pinocembrin (5,7-Dihydroxyflavanone) is a flavanone, a type of flavonoid. It is an antioxidant found in damiana, honey, fingerroot, and propolis.</p>Formula:C15H12O4Purity:99.61% - >99.99%Color and Shape:SolidMolecular weight:256.25MW-150 dihydrochloride dihydrate
CAS:<p>MW-150: selective CNS-penetrant p38α MAPK inhibitor, orally active, Ki 101 nM, blocks MK2 phosphorylation in glia.</p>Formula:C24H29Cl2N5O2Color and Shape:SolidMolecular weight:490.43Cediranib
CAS:<p>Cediranib (AZD2171) is a potent KDR tyrosine kinase inhibitor (IC50 < 1nM), also targets Flt1/4, PDGFRβ, c-Kit, and more selective for VEGFR.</p>Formula:C25H27FN4O3Purity:97.21% - 99.94%Color and Shape:SolidMolecular weight:450.51Tubastatin A Hydrochloride
CAS:<p>Tubastatin A Hydrochloride (TSA HCl) is an effective and specific HDAC6 inhibitor (IC50: 15 nM).</p>Formula:C20H21N3O2·HClPurity:97.24% - 99.15%Color and Shape:SolidMolecular weight:371.86Quizartinib
CAS:<p>Quizartinib (AC220) is an inhibitor of FLT3 (Kd: 1.6 nM) and demonstrates high selectivity for FLT3 when tested against a panel of 227 additional kinases.</p>Formula:C29H32N6O4SPurity:98% - 99.42%Color and Shape:SolidMolecular weight:560.67Apigenin
CAS:<p>Apigenin (NSC 83244) is an aromatic oil extracted from the flowers or leaves of the daisy-like plants.</p>Formula:C15H10O5Purity:97.64% - 99.66%Color and Shape:Yellow Needles From Aqueous Pyridine SolidMolecular weight:270.24U0126-EtOH
CAS:<p>U0126-etoh (U0126 Ethanol) is a non-ATP competitive inhibitor of MEK1 (IC50=72 nM) and MEK2 (IC50=58 nM) with selectivity, inhibit autophagy. Low-Cost!</p>Formula:C18H16N6S2·C2H6OPurity:99.72% - 99.88%Color and Shape:SolidMolecular weight:426.6Tenovin-6
CAS:<p>Tenovin-6 is a p53 transcriptional activity agonist.</p>Formula:C25H34N4O2SPurity:97.71% - >99.99%Color and Shape:SolidMolecular weight:454.63AZD1208
CAS:<p>AZD1208 is a novel, orally bioavailable, highly selective PIM kinase inhibitor with single nanomolar potency against all three PIM kinases.</p>Formula:C21H21N3O2SPurity:97.24% - 99.83%Color and Shape:SolidMolecular weight:379.48U0126
CAS:<p>U0126, an effective and selective non-competitive inhibitor of MAP kinase, inhibits MEK-1 and MEK-2 with IC50 values of 0.07 and 0.06 μM respectively.</p>Formula:C18H16N6S2Purity:99.61%Color and Shape:White SolidMolecular weight:380.49Torin 1
CAS:<p>Torin 1 is an effective inhibitor of mTORC1/2 with (IC50: 2 nM/10 nM); has 1000-fold selectivity for mTOR than PI3K.</p>Formula:C35H28F3N5O2Purity:98.3% - 99.33%Color and Shape:SolidMolecular weight:607.62Ligustilide
CAS:<p>3-Butylidene-4,5-dihydrophthalide is an effective constituent extracted from Angelica sinensis.</p>Formula:C12H14O2Purity:96.03% - 98.14%Color and Shape:Yellow Brown PowderMolecular weight:190.24Pinosylvin
CAS:<p>Pinosylvin (5-Styrylresorcinol) induces autophagy via AMPK activation. Pinosylvin is likely to act as a pro-angiogenic factor.</p>Formula:C14H12O2Purity:99.89% - 99.91%Color and Shape:SolidMolecular weight:212.24Berbamine dihydrochloride
CAS:<p>Berbamine dihydrochloride (Berbamine), a natural compound derived from the Berberis amurensis plant, has been shown to exhibit antitumor activity in several Ys.</p>Formula:C37H42Cl2N2O6Purity:95% - 99.99%Color and Shape:SolidMolecular weight:681.65Isosorbide Mononitrate
CAS:<p>Isosorbide Mononitrate (Corangin) is a Nitrate Vasodilator, dilating the blood vessels so as to reduce the blood pressure.</p>Formula:C6H9NO6Purity:98.16%Color and Shape:Isosorbide-5-Mononitrate Is A Crystalline Solid It Is Very Flammable And May Be Toxic By IngestionMolecular weight:191.14Entinostat
CAS:<p>Entinostat (MS-275) is an HDAC class I with oral activity. Entinostat has antitumor activity. Cost-effective and quality-assured.</p>Formula:C21H20N4O3Purity:98% - 99.74%Color and Shape:SolidMolecular weight:376.41CCT128930 hydrochloride
CAS:<p>CCT128930 hydrochloride: Potent AKT inhibitor (IC50=6 nM), 28x selective over PKA, 20x over p70S6K, induces cell cycle arrest & DNA damage.</p>Formula:C18H21Cl2N5Purity:98.55%Color and Shape:SolidMolecular weight:378.3Gartanin
CAS:<p>Gartanin enhances androgen receptor degradation and has neuroprotective effects by boosting HO-1, AMPK, SIRT1, and PGC-1α pathways.</p>Formula:C23H24O6Purity:99.64% - 99.85%Color and Shape:SolidMolecular weight:396.43KB-R7943 mesylate
CAS:<p>KB-R7943 mesylate is a widely used inhibitor of the reverse Na+/Ca2+ exchanger (NCXrev) with IC50 of 5.7±2.1 μM.</p>Formula:C17H21N3O6S2Purity:99.88% - ≥95%Color and Shape:SolidMolecular weight:427.5PTC-209 hydrobromide
CAS:<p>PTC-209 hydrobromide (PTC-209 HBr) is the hydrobromide salt of PTC-209, which is a potent and selective BMI-1 inhibitor with IC50 of 0.5 μM, and results in</p>Formula:C17H13Br2N5OS·HBrPurity:99.91%Color and Shape:SolidMolecular weight:576.1Autogramin-1
CAS:<p>Autogramin-1 potently inhibits starvation-induced autophagy with IC50 of 0.17 μM.</p>Formula:C23H27N5O5SPurity:97.69% - 99.25%Color and Shape:SolidMolecular weight:485.56XL388
CAS:<p>XL388 is a highly effective, specifc, ATP-competitive inhibitor of mTOR ( IC50: 9.9 nM), 1000-fold selectivity than the closely related PI3K kinases.</p>Formula:C23H22FN3O4SPurity:99.39% - 99.53%Color and Shape:SolidMolecular weight:455.5NSC 185058
CAS:<p>NSC 185058 is an inhibitor of ATG4B, a major cysteine protease. It also can attenuate the autophagic activity.</p>Formula:C11H9N3SPurity:99.27%Color and Shape:SolidMolecular weight:215.27PF-543 hydrochloride
CAS:<p>PF-543 hydrochloride (PF-543) inhibits SphK1 with a K(i) of 3.6 nM, is sphingosine-competitive and is more than 100-fold selective for SphK1 over the SphK2</p>Formula:C27H32ClNO4SPurity:98.9% - 99.93%Color and Shape:SolidMolecular weight:502.1URMC-099
CAS:<p>URMC-099: oral, brain-accessible MLK/LRRK2 inhibitor; IC50 – MLK1/2/3/DLK: 19/42/14/150 nM, LRRK2: 11 nM.</p>Formula:C27H27N5Purity:99.32% - 99.98%Color and Shape:SolidMolecular weight:421.54Autocamtide-2-related inhibitory peptide
CAS:<p>Autocamtide-2-related inhibitory peptide is a highly specific and potent inhibitor of CaMKII with an IC50 of 40 nM.</p>Formula:C64H116N22O19Purity:>99.99%Color and Shape:SolidMolecular weight:1497.74PF-06447475
CAS:<p>PF-06447475 is a highly effective, specific, brain penetrant LRRK2 inhibitor with IC0 of 3/11 nM for wild type LRRK2 and G2019S LRRK2 respectively.</p>Formula:C17H15N5OPurity:98.61% - 99.62%Color and Shape:SolidMolecular weight:305.33Onjisaponin B
CAS:<p>Onjisaponin B induces autophagy via the AMPK-mTOR signaling pathway, increases the NGF level and accelerates both the removal of mutant huntingtin and A53T α±-</p>Formula:C75H112O35Purity:99.20% - 99.972%Color and Shape:SolidMolecular weight:1573.67A-867744
CAS:<p>A-867744 is an effective and selective type II positive allosteric modulator of the α7 nAChR (EC50: 1.0 μM).</p>Formula:C20H19ClN2O3SPurity:95.66%Color and Shape:SolidMolecular weight:402.89Briciclib
CAS:<p>Briciclib (ON 014185) is a small molecule that suppresses cyclin D1 accumulation in Y cells.</p>Formula:C19H23O10PSPurity:98% - 99.84%Color and Shape:SolidMolecular weight:474.42TA-01
CAS:<p>TA-01 is a potent CK1 and p38 MAPK inhibitor, with IC50s of 6.4 nM, 6.8 nM, 6.7 nM for CK1ε, CK1δ and p38 MAPK, respectively.</p>Formula:C20H12F3N3Purity:99.55% - 99.94%Color and Shape:SolidMolecular weight:351.32PI3Kδ-IN-15
CAS:<p>CAL-101 (Idelalisib) is a selective inhibitor of p110δ; shown to have 40- to 300-fold greater selectivity for p110δ than p110α/β/γ.</p>Formula:C21H16FN7OPurity:99.61%Color and Shape:SolidMolecular weight:401.4Lanatoside C
CAS:<p>Lanatoside C, a cardiac glycoside, treats heart failure and arrhythmia; taken orally or IV.</p>Formula:C49H76O20Purity:98.3% - >99.99%Color and Shape:SolidMolecular weight:985.12Spautin-1
CAS:<p>Spautin-1 is an autophagy inhibitor that can suppress the deubiquitination activity of ubiquitin-specific peptidase USP10 and USP13. Cost-effective and quality-assured.</p>Formula:C15H11F2N3Purity:97.69% - 98.99%Color and Shape:SolidMolecular weight:271.26Sofalcone
CAS:<p>Sofalcone (SU-88), a gastric antiulcer agent in clinical use, is known to induce the expression of Heme oxygenase-1 (HO-1) in gastric epithelium.</p>Formula:C27H30O6Purity:97.55%Color and Shape:SolidMolecular weight:450.52Hesperadin
CAS:<p>Hesperadin(IC50=250 nM) effectively inhibits Aurora B.</p>Formula:C29H32N4O3SPurity:98.04% - 99.44%Color and Shape:SolidMolecular weight:516.65Nitroprusside disodium dihydrate
CAS:<p>Nitroprusside disodium dihydrate (Sodium Nitroprusside Dihydrate) is a potent vasodilator working through releasing NO spontaneously in blood.</p>Formula:C5H4FeN6Na2O3Purity:98%Color and Shape:Bright RedMolecular weight:297.95UNC1999
CAS:<p>UNC1999 is a orally bioavailable, effective and specific inhibitor of EZH2 (IC50=2 nM) and EZH1 (IC50=45).</p>Formula:C33H43N7O2Purity:99.19% - >99.99%Color and Shape:SolidMolecular weight:569.74SAR405
CAS:<p>SAR-405 inhibits PIK3C3/Vps34 (IC50: 1.2 nM, Kd: 1.5 nM), blocks autophagy, and enhances MTOR inhibitor effects on cancer cells.</p>Formula:C19H21ClF3N5O2Purity:99.42% - 99.79%Color and Shape:SolidMolecular weight:443.85AZ304
CAS:<p>AZ304 is an ATP-competitive dual BRAF kinase inhibitor, potently inhibits BRAF (WT), BRAF (V600E), and wild type CRAF (IC50s: 79/38/68 nM).</p>Formula:C27H25N5O2Purity:99.82%Color and Shape:SolidMolecular weight:451.52Ivacaftor
CAS:<p>Ivacaftor (VX-770) (VX-770) is a potentiator of CFTR targeting G551D-CFTR (EC50: 100 nM) and F508del-CFTR (EC50: 25 nM) in Fisher rat thyroid cells,</p>Formula:C24H28N2O3Purity:99% - 99.98%Color and Shape:SolidMolecular weight:392.49α-Thujone
CAS:<p>α-Thujone is an inhibitor of ACh with an IC50 value of 24.7μM.</p>Formula:C10H16OPurity:97.02% - 98.41%Color and Shape:Less Or Almost Colorless Liquid With A Menthol- Like Odor (Albert-Puleo 1978; Budavari 1996) Colorless Or Almost Colorless Liquid With A Menthol- Like Odor (Albert-Puleo 1978; Budavari 1996)Molecular weight:152.23Fasudil dihydrochloride
CAS:<p>Fasudil dihydrochloride (HA-1077/AT877) is a RhoA/ROCK inhibitor with kinase-blocking properties and acts as a vasodilator.</p>Formula:C14H19Cl2N3O2SColor and Shape:SolidMolecular weight:364.29Urolithin A
CAS:<p>Urolithin A is a metabolite of ellagic acid, which inhibits DNA synthesis and induces apoptosis and autophagy. Cost-effective and quality-assured.</p>Formula:C13H8O4Purity:99.14% - 99.67%Color and Shape:SolidMolecular weight:228.2Omipalisib
CAS:<p>Omipalisib (GSK2126458) is a small-molecule pyridylsulfonamide inhibitor of phosphatidylinositol 3-kinase (PI3K) with potential antineoplastic activity.</p>Formula:C25H17F2N5O3SPurity:98% - 99.8%Color and Shape:SolidMolecular weight:505.5Vps34-IN-1
CAS:<p>Vps34-IN-1: potent, selective Vps34 inhibitor, 25 nM IC50, spares class I/II PI3Ks.</p>Formula:C21H24ClN7OPurity:97.04%Color and Shape:SolidMolecular weight:425.91OSI-027
CAS:<p>OSI-027 (ASP4786) is a selective and potent dual inhibitor of mTORC1 and mTORC2 with IC50 of 22 nM and 65 nM.</p>Formula:C21H22N6O3Purity:97.42%Color and Shape:SolidMolecular weight:406.44Nocodazole
CAS:<p>Nocodazole: synthetic microtubule polymerization blocker, also impedes Abl with low IC50; binds to beta-tubulin.</p>Formula:C14H11N3O3SPurity:98% - 99.91%Color and Shape:Physical Description White Powder (Ntp 1992)Molecular weight:301.32Atorvastatin hemicalcium trihydrate
CAS:<p>Atorvastatin hemicalcium trihydrate, an oral HMG-CoA reductase inhibitor, lowers blood lipids and inhibits SV-SMC with IC50s: 0.39/2.39 μM.</p>Formula:C33H35FN2O5Ca·3H2OColor and Shape:SolidMolecular weight:632.73Aliskiren hydrochloride
CAS:<p>Aliskiren (CGP 60536; CGP60536B; SPP 100) hydrochloride is a selective, orally active, renin inhibitor (IC50: 1.5 nM). Cachexia.</p>Formula:C30H54ClN3O6Color and Shape:SolidMolecular weight:588.23Nesolicaftor
CAS:<p>Nesolicaftor (PTI-428) specifically enhances cystic fibrosis transmembrane conductance regulator protein synthesis.</p>Formula:C18H18N4O4Purity:99.79%Color and Shape:SolidMolecular weight:354.36SP600125
CAS:<p>SP600125 (JNK Inhibitor II) is a JNK inhibitor that inhibits JNK1, JNK2, and JNK3 (IC50=40/40/90 nM) with oral potency, reversibility, and ATP-competitive</p>Formula:C14H8N2OPurity:97.63% - 99.82%Color and Shape:SolidMolecular weight:220.23XCT790
CAS:<p>XCT790 is a potent, selective and inverse agonist of estrogen-related receptor alpha(ERRα).</p>Formula:C23H13F9N4O3SPurity:99% - 99.61%Color and Shape:SolidMolecular weight:596.42Lithocholic acid
CAS:<p>Lithocholic acid (3α-Hydroxy-5β-cholanic acid) is a toxic secondary bile acid, They were FXR antagonists (IC50=0.7, 1.4 μM). High-Quality, Low-Cost!</p>Formula:C24H40O3Purity:99.69% - 99.93%Color and Shape:Hexagonal Leaflets From Alc Prisms From Acetic Acid Powder (Ntp 1992)Molecular weight:376.57EIPA
CAS:<p>EIPA (L593754) is a TRPP3 channel inhibitor and an inhibitor of Na+/H+ exchange (NHE). EIPA inhibits megacytosis, promotes autophagy. Cost-effective and quality-assured.</p>Formula:C11H18ClN7OPurity:96.62% - 99.981%Color and Shape:Off-White To Yellow SolidMolecular weight:299.76SBI-0206965
CAS:<p>SBI-0206965 is a potent, selective and cell-permeable autophagy kinase ULK1 inhibitor with IC50 of 108 nM for ULK1 kinase activity and 711 nM for ULK2.</p>Formula:C21H21BrN4O5Purity:99.13%Color and Shape:SolidMolecular weight:489.32Crenolanib
CAS:<p>Crenolanib (ARO 002) is an orally bioavailable type III tyrosine kinases inhibitor of PDGFRα/β and FLT3 (IC50s: 11, 3.2, and 4 nM).</p>Formula:C26H29N5O2Purity:98.40% - 99.73%Color and Shape:SolidMolecular weight:443.544,4'-Dimethoxychalcone
CAS:<p>4,4'-Dimethoxychalcone (4,4-Dimethoxychalcone) is a natural product.</p>Formula:C17H16O3Purity:99.57%Color and Shape:SolidMolecular weight:268.31AG490
CAS:<p>AG490 inhibits EGFR (0.1 μM IC50), 135x > selective than ErbB2, blocks JAK2, spares Lyn, Lck, Syk, Btk, Src.</p>Formula:C17H14N2O3Purity:98.6% - 99.39%Color and Shape:Yellow SolidMolecular weight:294.3PF-06454589
CAS:<p>PF-06454589 is a potent inhibitor of LRRK2.</p>Formula:C14H16N6OPurity:99.06%Color and Shape:SolidMolecular weight:284.32Lumacaftor
CAS:<p>Lumacaftor (VRT 826809) is a CFTR modulator that corrects the folding and trafficking of CFTR protein.</p>Formula:C24H18F2N2O5Purity:99.48% - 99.68%Color and Shape:SolidMolecular weight:452.41ULK-101
CAS:<p>ULK-101 is a potent and selective ULK1 inhibitor ( IC50s: 8.3/30 nM for ULK1/ULK2). It can suppress autophagy.</p>Formula:C22H16F4N4OSPurity:97.55% - 99.94%Color and Shape:SolidMolecular weight:460.45Ixazomib citrate
CAS:<p>Ixazomib citrate (MLN9708), a prodrug of Ixazomib (MMLN-2238), is an oral 2nd-gen proteasome inhibitor with anti-cancer potential (IC50: 3.4 nM).</p>Formula:C20H23BCl2N2O9Purity:98.37% - >99.99%Color and Shape:SolidMolecular weight:517.12Regorafenib mesylate
CAS:<p>Regorafenib mesylate is an oral multi-kinase inhibitor targeting VEGFR, PDGFRβ, Kit, RET, Raf-1 with strong anti-tumor and anti-angiogenic effects.</p>Formula:C22H19ClF4N4O6SColor and Shape:SolidMolecular weight:578.92MLN9708 analogues
CAS:<p>MLN2238 inhibits 20S proteasome's β5 site (Ki50=0.93 nM, IC50=3.4 nM), active form of Ixazomib Citrate in solutions/plasma.</p>Formula:C20H23BCl2N2O9Purity:98.24% - 99.23%Color and Shape:SolidMolecular weight:517.12Tepotinib hydrochloride(1 : x)
CAS:<p>Tepotinib hydrochloride(1 : x) is an orally bioavailable, mesenchymal-epithelial transition (MET) TKI developed mainly for selected NSCLC patients with METex14</p>Formula:C29H29ClN6O2Purity:99.81%Color and Shape:SolidMolecular weight:529.04Degrasyn
CAS:<p>Degrasyn (WP1130) inhibits DUBs (USP5, UCH-L1, USP9x, USP14, UCH37) and Bcr/Abl without affecting the 20S proteasome.</p>Formula:C19H18BrN3OPurity:98.32% - 99.98%Color and Shape:SolidMolecular weight:384.27Trifluoperazine
CAS:<p>Trifluoperazine (trifluoroperazine) is a Dopamine D2 receptor inhibitor(IC50 : 1.2 nM), and Treatment of schizophrenia.</p>Formula:C21H24F3N3SPurity:98.3% - 99.46%Color and Shape:White To Yellowish Crystalline PowderMolecular weight:407.5E-64
CAS:<p>E-64 (Proteinase inhibitor E 64) is an irreversible and specific cysteine protease inhibitor. The IC50 of E-64 for papain is 9 nM.</p>Formula:C15H27N5O5Purity:98% - 99.95%Color and Shape:White SolidMolecular weight:357.41Paeonol
CAS:<p>Paeonol (Peonol) is an active extraction from Paeonia suffruticosa. Paeonol inhibits MAO-A and MAO-B with IC50 of 54.6 μM and 42.5 μM, respectively.</p>Formula:C9H10O3Purity:98.55% - 99.56%Color and Shape:White To Beige Crystalline PowderMolecular weight:166.17Hoechst 33342 trihydrochloride
CAS:<p>Hoechst 33342 trihydrochloride (bisBenzimide H 33342 trihydrochloride;HOE 33342 trihydrochloride) is a membrane permeant DNA stain with blue fluorescence.</p>Formula:C27H31Cl3N6OPurity:98.73% - ≥98%Color and Shape:SolidMolecular weight:561.93SN-38
CAS:<p>SN-38 (NK012) is the active metabolite of Irinotecan, a DNA topoisomerase I (Topo I) inhibitor, which inhibits DNA and RNA synthesis (IC50=0.077/1.3 μM).</p>Formula:C22H20N2O5Purity:98% - 99.97%Color and Shape:Light-Yellow SolidMolecular weight:392.4Vps34-PIK-III
CAS:<p>Vps34-PIK-III (VPS34-IN2), a selective inhibitor of VPS34 enzymatic activity, inhibits autophagy and results in the stabilization of autophagy substrates.</p>Formula:C17H17N7Purity:98.39% - 98.43%Color and Shape:SolidMolecular weight:319.36UM-164
CAS:<p>UM-164 (DAS-DFGO-II), a highly potent c-Src inhibitor with a dissociation constant (Kd) of 2.7 nM, also effectively inhibits p38α and p38β.</p>Formula:C30H31F3N8O3SPurity:98.72% - 99.52%Color and Shape:SolidMolecular weight:640.68LYS01
CAS:<p>LYS01 free base is a new lysosomal autophagy inhibitor.</p>Formula:C23H23Cl2N5Purity:98.28%Color and Shape:SolidMolecular weight:440.37Rottlerin
CAS:<p>Rottlerin (NSC-56346), a Mallotus Philippinensis extract, inhibits PKC (3-100 μM IC50); triggers apoptosis by activating caspase 3.</p>Formula:C30H28O8Purity:97.41% - 99.44%Color and Shape:Orange To Brown PowderMolecular weight:516.54Sertaconazole nitrate
CAS:<p>Sertaconazole nitrate, a broad-spectrum topical antifungal, treats skin and mucosal infections.</p>Formula:C20H15Cl3N2OS·HNO3Purity:98.66% - 99.65%Color and Shape:SolidMolecular weight:500.78Meglutol
CAS:<p>Meglutol, a cholesterol and triglyceride reducing antilipemic, hinders key enzymes in cholesterol biosynthesis.</p>Formula:C6H10O5Purity:99.73% - 99.94%Color and Shape:SolidMolecular weight:162.14Rosiglitazone hydrochloride
CAS:<p>Rosiglitazone hydrochloride (BRL-49653 HCl) is a blood glucose-lowering drugs, stimulating insulin secretion by binding to the PPAR receptors in fat cells.</p>Formula:C18H19N3O3S·HClPurity:99.63% - 99.79%Color and Shape:SolidMolecular weight:393.89Olaparib
CAS:<p>View and buy Olaparib from TargetMol.Olaparib is a small molecule inhibitor of PARP1/PARP2.Cited in 10 publications.</p>Formula:C24H23FN4O3Purity:98% - >99.99%Color and Shape:SolidMolecular weight:434.46Azithromycin
CAS:<p>Azithromycin (CP 62993) is a macrolide antibiotic that primarily targets the 50S subunit of bacterial ribosomes. High-Quality, Low-Cost!</p>Formula:C38H72N2O12Purity:99.9% - 99.97%Color and Shape:White To Off-White Solid CrystallineMolecular weight:748.98MRT68921 dihydrochloride
CAS:<p>MRT68921 dihydrochloride is a potent ULK1 and ULK2 inhibitor (IC50 of 2.9 nM and 1.1 nM, respectively).</p>Formula:C25H36Cl2N6OPurity:98.91% - 99.92%Color and Shape:SolidMolecular weight:507.499MG-132
CAS:<p>MG-132 (Z-Leu-Leu-Leu-al) is a 26S proteasome inhibitor, cell-permeable and reversible,an autophagy activator, induces apoptosis. High-Quality, Low-Cost!</p>Formula:C26H41N3O5Purity:95% - 99.99%Color and Shape:White To Off-White PowderMolecular weight:475.62Pexmetinib
CAS:<p>Pexmetinib (ARRY-614) is an orally bioavailable dual p38 MAPK/Tie-2 inhibitor.Cost-effective and quality-assured.</p>Formula:C31H33FN6O3Purity:99.07% - 99.66%Color and Shape:SolidMolecular weight:556.63Clinofibrate
CAS:<p>Clinofibrate lowers lipids, blocks HMGCR (IC50: 0.47 mM), and controls cholesterol/triacylglycerides.</p>Formula:C28H36O6Purity:>99.99%Color and Shape:White Crystalline PowderMolecular weight:468.58Venetoclax
CAS:<p>Venetoclax (ABT-199) is a selective inhibitor of Bcl-2 (Ki < 0.010 nM), binding over 3 orders of magnitude less avidly to Bcl-xL, and Bcl-W (Kis = 48/245 nM).</p>Formula:C45H50ClN7O7SPurity:98.00% - 99.97%Color and Shape:SolidMolecular weight:868.44Sevelamer hydrochloride
CAS:<p>Sevelamer hydrochloride (Sevelamer HCl) is a phosphate binding drug used to treat hyperphosphatemia via binding to dietary phosphate and prevents its absorption</p>Formula:(C3H7N·C3H5ClO·HCl)xPurity:98%Color and Shape:SolidMolecular weight:186.08Idelalisib
CAS:<p>Idelalisib (GS-1101) is a small molecule inhibitor of the PI3K catalytic subunit p110δ (IC50: 2.5 nM).</p>Formula:C22H18FN7OPurity:98% - 99.39%Color and Shape:SolidMolecular weight:415.42Cucurbitacin B
CAS:<p>Cucurbitacin B (Cuc B) has profound in vitro and in vivo antiproliferative effects against human pancreatic Y cells.</p>Formula:C32H46O8Purity:97.1% - 99.33%Color and Shape:SolidMolecular weight:558.7PATULIN
CAS:<p>Patulin (Claviform) is a mycotoxin produced by a variety of molds commonly found in rotting apples, including Aspergillus and Penicillium.</p>Formula:C7H6O4Purity:99.91% - 99.98%Color and Shape:Compact Prisms Or Thick Plates From Ether Or Chloroform White CrystallineMolecular weight:154.12
