GPCR/G-Protein

GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.

Subcategories of "GPCR/G-Protein"

Show 18 more subcategories

Found 5378 products of "GPCR/G-Protein"

Purity (%)

100

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BE-24566B
CAS:
- 149466-04-6
BE-24566B, a polyketide from S. violaceusniger, inhibits various bacteria and blocks ET receptors (ETA IC50=11 μM, ETB=3.9 μM).
Formula:C₂₇H₂₄O₇
Color and Shape:Solid
Molecular weight:460.482
Ref: TM-T38167
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Desglymidodrine
CAS:
- 3600-87-1
Desglymidodrine (ST 1059) is an α1-adrenoceptor agonist and vasoconstrictor, used in cardiovascular research and neurocardiogenic syncope studies.
Formula:C₁₀H₁₅NO₃
Purity:99.56%
Color and Shape:Solid
Molecular weight:197.23
Ref: TM-T31388L
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CB1R antagonist 2
CB1R antagonist 2 (Compound 11g) functions as an antagonist of the cannabinoid receptor 1 (CB1R), inhibiting the MAPK/NF-κB signaling pathway and exhibiting anti-inflammatory properties. In RAW264.7 cells, it suppresses LPS-induced expression of IL-6, IL-1β, and TNF-α. In murine models, it improves OVA-induced allergic rhinitis.
Formula:C₂₄H₂₆N₄O
Color and Shape:Solid
Molecular weight:386.49
Ref: TM-T205110
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TDI-10229
CAS:
- 2810887-45-5
TDI-10229: potent oral sAC inhibitor, IC50=195 nM. Good mouse pharmacokinetics for in vivo use.
Formula:C₁₆H₁₆ClN₅
Purity:99.85% - 99.89%
Color and Shape:Soild
Molecular weight:313.78
Ref: TM-T64355
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MD01-67
CAS:
- 2468971-42-6
MD01-67 is a macrocyclic compound selectively targeting the neurotensin 2 receptor (NTS2), with a Ki of 2.9 nM. It exhibits analgesic activity and reduces tactile hypersensitivity in rat models of acute, sustained, and chronic inflammatory pain.
Formula:C₃₇H₅₈N₈O₈
Color and Shape:Solid
Molecular weight:742.91
Ref: TM-TP2936
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Benzquinamide
CAS:
- 63-12-7
Benzquinamide (P2647), an antiemetic agent with anticancer activity, inhibits p-glycoprotein-mediated drug efflux and potentiates the cytotoxicity of anticancer
Formula:C₂₂H₃₂N₂O₅
Purity:94.86%
Color and Shape:Solid
Molecular weight:404.5
Ref: TM-T12343
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BMY-14802
CAS:
- 105565-56-8
BMY-14802 (alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol) is a selective and orally active sigma-1 antagonist with an IC50 of 112 nM.
Formula:C₁₈H₂₂F₂N₄O
Purity:99.84%
Color and Shape:Soild
Molecular weight:348.39
Ref: TM-T67739
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G-Protein antagonist peptide acetate
G-Protein antagonist peptide acetate is a truncated substance P-related peptide, competes with receptor for G protein binding.
Formula:C₅₉H₆₈N₁₂O₁₁S
Purity:98.06%
Color and Shape:Solid
Molecular weight:1153.33
Ref: TM-TP1902L1
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[Ala1,3,11,15]-Endothelin
CAS:
- 121204-87-3
Selective ETB endothelin receptor agonist (IC50 values are 0.33 and 2200 nM for displacing [125I]-ET-1 from ETB and ETA receptors respectively).
Formula:C₁₀₉H₁₆₃N₂₅O₃₂S
Purity:98%
Color and Shape:Solid
Molecular weight:2368
Ref: TM-TP2099
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SKF-83566 hydrochloride
CAS:
- 164265-49-0
SKF-83566 hydrochloride is a D1-like dopamine receptor antagonist, inhibiting dopamine transporters and mitigating GBP-induced CPP.
Formula:C₁₇H₁₉BrClNO
Purity:99.27%
Color and Shape:Soild
Molecular weight:368.69
Ref: TM-T8702L
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Metipranolol
CAS:
- 22664-55-7
Metipranolol (Betamann) is a type of β- Adrenergic receptors（ β- A potent antagonist of adrenergic receptor on guinea pig atria β 1- Adrenergic receptors and rat uterus β The 2-adrenergic receptor exhibited the beta blocking potentials (pA2) of 8.3 and 8.4, respectively. It is also a potent substituent in the 3H DHA binding assay, with a ligand concentration of 0.7 nM and a Ki of 39 ± 24 nM.
Formula:C₁₇H₂₇NO₄
Purity:98.37%
Color and Shape:Solid
Molecular weight:309.4
Ref: TM-T8899
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Oxmetidine FA
Oxmetidine FA is an orally available specific histamine H2 receptor antagonist with antiulcerogenic properties.
Formula:C₂₀H₂₃N₅O₅S
Purity:97.34%
Color and Shape:Soild
Molecular weight:445.49
Ref: TM-T68122L
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16-phenoxy tetranor Prostaglandin F2α methyl ester
CAS:
- 51638-90-5
Prostaglandin F2α (PGF2α) drives luteolysis and smooth muscle contraction by activating the FP receptor.
Formula:C₂₃H₃₂O₆
Color and Shape:Solid
Molecular weight:404.503
Ref: TM-T37937
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CH 275
CAS:
- 174688-78-9
Potent sst1 agonist with 30.9 nM IC50; selective over sst2-5; inhibits somatostatin in rat nucleus accumbens.
Formula:C₇₄H₉₆N₁₄O₁₅S₂
Purity:98%
Color and Shape:Solid
Molecular weight:1485.8
Ref: TM-TP2045
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Plecanatide acetate
CAS:
- 1075732-84-1
Plecanatide acetate: GC-C receptor agonist, EC50=190 nM (T84 cells), anti-inflammatory in murine colitis.
Formula:C₆₇H₁₀₈N₁₈O₂₈S₄
Purity:98%
Color and Shape:Solid
Molecular weight:1741.94
Ref: TM-T12501
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S1P2 antagonist 1
CAS:
- 2262402-83-3
S1P2 antagonist 1 is an orally bioavailable S1P2 antagonist against fibrotic diseases.
Formula:C₂₃H₂₁ClN₄O₄
Color and Shape:Solid
Molecular weight:452.9
Ref: TM-T39798
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Proglumide hemicalcium
CAS:
- 85068-56-0
Proglumide hemicalcium is a antagonist of nonpeptide and orally active cholecystokinin (CCK)-A/B receptors, has antiepileptic and antioxidant activities.
Formula:C₁₈H₂₈CaN₂O₄
Purity:98%
Color and Shape:Solid
Molecular weight:376.51
Ref: TM-T12544
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GIP/GLP-1 dual receptor agonist-1
CAS:
- 2807481-02-1
Compound 4: GIP/GLP-1 agonist for metabolic/fatty liver disease research.
Color and Shape:Solid
Ref: TM-T75150
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S1R agonist 2
CAS:
- 150085-21-5
S1R agonist 2 is a selective S1R agonist with a Ki of 88 nM for S2R and 1.1 nM for S1R and is protective against ROS and NMDA-induced neurotoxicity.
Formula:C₂₁H₂₇NO
Purity:98.85%
Color and Shape:Solid
Molecular weight:309.45
Ref: TM-T72059
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Bamosiran
CAS:
- 1337968-84-9
Bamosiran, a small interfering RNA (siRNA), specifically targets the β-adrenergic receptor 2 to reduce intraocular pressure.
Color and Shape:Solid
Ref: TM-T75155
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PEN (rat)
CAS:
- 569364-13-2
PEN (rat) is an Endogenous peptide GPR83 agonist. ProSAAS-derived neuropeptide.
Formula:C₁₀₂H₁₆₉N₂₇O₃₃
Purity:98%
Color and Shape:Solid
Molecular weight:2301.62
Ref: TM-TP1951
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Kisspeptin 234
CAS:
- 1145998-81-7
Kisspeptin receptor antagonist; blocks kisspeptin-10 effects on IP (IC50 = 7 nM) and GnRH release.
Formula:C₆₃H₇₈N₁₈O₁₃
Purity:98%
Color and Shape:Solid
Molecular weight:1295.42
Ref: TM-TP1896
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PSB-SB-1203
CAS:
- 1399049-80-9
PSB-SB-1203 (Compound 25b) is a dual CB1/CB2 ligand that blocks the CB1 receptor and activates the CB2 receptor with a CB1 Ki of 0.244 μM, a CB2 Ki of 0.210 μM, and an EC50 of 0.054 μM. It shows potential for research in obesity and cancer.
Formula:C₂₅H₃₀O₄
Color and Shape:Solid
Molecular weight:394.5
Ref: TM-T203067
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Israpafant
CAS:
- 117279-73-9
Israpafant: PAF receptor blocker, IC50 0.84nM, hinders platelet aggregation, eosinophil activation, boosts calcium transit, anti-nephrotoxic.
Formula:C₂₈H₂₉ClN₄S
Color and Shape:Solid
Molecular weight:489.07
Ref: TM-T27638
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Sulfatroxazole
CAS:
- 23256-23-7
Sulfatroxazole (Isosulfafurazole) (compound 12) is a selective antagonist of the ETA receptor with an IC50 of 0.26 μM.
Formula:C₁₁H₁₃N₃O₃S
Color and Shape:Solid
Molecular weight:267.3
Ref: TM-T203689
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CACPD2011a-0001278239
CAS:
- 1030781-08-8
CACPD2011a-0001278239 is a β2AR hybrid agonist with high affinity binding to both the wild-type and T164I β2AR variants. It exhibits neither cytotoxicity nor mutagenicity, making it suitable for asthma research.
Formula:C₂₁H₂₂N₄O₄
Color and Shape:Solid
Molecular weight:394.42
Ref: TM-T203578
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Esprolol
CAS:
- 396654-09-4
Esprolol (ACC-9369 free base) is a novel beta-adrenergic antagonist used to study exertional angina.
Formula:C₁₇H₂₇NO₄
Purity:71.58% - 99.16%
Color and Shape:Soild
Molecular weight:309.4
Ref: TM-T27286L
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NPC 567
CAS:
- 109333-26-8
NPC 567 is an antagonist of the bradykinin receptor.
Formula:C₆₀H₈₇N₁₉O₁₃
Purity:98%
Color and Shape:Solid
Molecular weight:1282.48
Ref: TM-T21060
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Satavaptan
CAS:
- 185913-78-4
Satavaptan is a vasopressin V2 receptor antagonist. Satavaptan improves the control of ascites in cirrhosis.
Formula:C₃₃H₄₅N₃O₈S
Color and Shape:Solid
Molecular weight:643.79
Ref: TM-T28664
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ELA-21 (human)
CAS:
- 2245073-05-4
Apelin receptor agonist with high affinity for normal/PAH hearts (pKi 9.31/9.46). Blocks cAMP, promotes β-arrestin in vitro. Part of ELA-32.
Formula:C₁₁₂H₁₈₄N₄₀O₂₅S₃
Purity:98%
Color and Shape:Solid
Molecular weight:2587.12
Ref: TM-TP2096
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Cannabidivarinic acid
CAS:
- 31932-13-5
Cannabidivarinic acid (CBDVA), the carboxylic acid precursor to cannabidivarin (CBDV), is a non-psychoactive cannabinoid found in Cannabis and known for its anti-inflammatory properties.
Formula:C₂₀H₂₆O₄
Color and Shape:Solid
Molecular weight:330.42
Ref: TM-T203665
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Esmolol acid hydrochloride
CAS:
- 83356-60-9
Esmolol acid (ASL-8123) hydrochloride is a mild antagonist of β-adrenergic receptors. It inhibits the heart rate and diastolic pressure responses induced by Isoproterenol in a dose-dependent manner and is applicable for renal failure research.
Formula:C₁₅H₂₄ClNO₄
Color and Shape:Solid
Molecular weight:317.81
Ref: TM-T203119
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Norisoboldine hydrochloride
CAS:
- 5083-84-1
Norisoboldine hydrochloride: an oral AhR agonist from Radix Linderae, for Rheumatoid arthritis and Ulcerative colitis research.
Formula:C₁₈H₂₀ClNO₄
Color and Shape:Solid
Molecular weight:349.81
Ref: TM-T75433
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S(-)-Bisoprolol fumarate
CAS:
- 1426853-23-7
S(-)-Bisoprolol fumarate is a selective β1-blocker for hypertension and heart research.
Formula:C₁₈H₃₁NO₄·xC₄H₄O₄
Color and Shape:Solid
Molecular weight:441.521
Ref: TM-T74156
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Apelin-17(human, bovine)
CAS:
- 217082-57-0
Endogenous apelin receptor agonist. Potently inhibits forskolin-stimulated cAMP accumulation (pIC50 = 9.94).
Formula:C₉₆H₁₅₆N₃₄O₂₀S
Purity:98%
Color and Shape:Solid
Molecular weight:2138.56
Ref: TM-TP2092
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ATMW-2
ATMW-2 is an antagonist engineered using NeuralGenThesis (NGT) technology, specifically targeting the melanocortin 2 receptor (MC2R).
Formula:C₂₇H₂₉ClN₂O₄
Color and Shape:Solid
Molecular weight:480.98
Ref: TM-T203063
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Moperone
CAS:
- 1050-79-9
Moperone (R 1658) is an antagonist of both the D2 dopamine receptor (D2 dopamine receptor) and the D3 dopamine receptor (D3 dopamine receptor), with IC50 values for each of 1.0 nM.
Formula:C₂₂H₂₆FNO₂
Color and Shape:Solid
Molecular weight:355.45
Ref: TM-T203131
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GLP-1 receptor agonist 8
CAS:
- 2401892-86-0
GLP-1 receptor agonist 8, potent for diabetes and obesity research, may also study NAFLD.
Formula:C₃₄H₃₆ClFN₆O₄
Color and Shape:Solid
Molecular weight:647.14
Ref: TM-T74132
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Eletriptan
CAS:
- 143322-58-1
Eletriptan, second-generation triptans used to treat migraines, is used as an abortion drug.
Formula:C₂₂H₂₆N₂O₂S
Color and Shape:Solid
Molecular weight:382.52
Ref: TM-T0216L
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7-Methyl DMT
CAS:
- 65882-39-5
7-Methyl DMT (7-TMT) acts as a 5-HT2 receptor agonist. Structurally, it is a tryptamine derivative and serves as an analytical reference for the psychoactive substance DOM. It is also applicable in research related to neurological disorders.
Formula:C₁₃H₁₈N₂
Color and Shape:Solid
Molecular weight:202.3
Ref: TM-T203196
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Methamnetamine hydrochloride
CAS:
- 2748623-12-1
Methamnetamine (PAL-1046) hydrochloride is a psychoactive substance derived from phenethylamine, known to cause excessive serotonin release.
Formula:C₁₄H₁₈ClN
Color and Shape:Solid
Molecular weight:235.75
Ref: TM-T203312
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δ8-THC acetate
CAS:
- 23050-54-6
Delta8-THC acetate (Delta8-tetrahydrocannabinol) is a psychoactive cannabinoid that binds to the cannabinoid receptor 1 (CB1 receptor) and exhibits anti-nausea, appetite-stimulating, and anti-inflammatory effects. It may also offer neuroprotective benefits and has potential applications in research on anxiety and depression.
Formula:C₂₃H₃₂O₃
Color and Shape:Solid
Molecular weight:356.5
Ref: TM-T203037
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S1R agonist 1
CAS:
- 193354-70-0
Compound 6b: Selective S1R agonist, K i = 0.93 nM (S1R), 72 nM (S2R); neuroprotective against ROS, NMDA toxicity.
Formula:C₂₀H₂₅NO
Color and Shape:Solid
Molecular weight:295.42
Ref: TM-T74822
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Kinetensin
CAS:
- 103131-69-7
Kinetensin is a neurotensin-like peptide.
Formula:C₅₆H₈₅N₁₇O₁₁
Purity:98%
Color and Shape:White Lyophilised Solid
Molecular weight:1172.38
Ref: TM-TP1116
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Amylin, amide, rat
CAS:
- 124447-81-0
Amylin: peptide, 50% similar to CGRP, found with somatostatin in stomach cells, reduces acid secretion in mice.
Formula:C₁₆₇H₂₇₂N₅₂O₅₃S₂
Purity:99.92%
Color and Shape:Solid
Molecular weight:3920.44
Ref: TM-TP1232
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SBI-810
CAS:
- 1849603-79-7
SBI-810 is a functional selective β-arrestin-biased allosteric modulator of the neurotensin receptor 1 (NTSR1). In the presence of the endogenous ligand neurotensin (NT), SBI-810 regulates NTSR1 signaling through a G protein-specific mechanism. It fully antagonizes NT-induced Gq activation and partially antagonizes NT-induced Gi1 activation, allowing NTSR1 to activate GoA and G12.
Formula:C₂₇H₃₄N₄O₂
Color and Shape:Solid
Molecular weight:446.59
Ref: TM-T203513
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CB2 receptor agonist 9
CAS:
- 2374894-21-8
CB2 receptor agonist 9 (Compound 33) is an orally active agonist of cannabinoid receptor 2 (CB2 receptor) with an EC50 of 16.2 nM. It inhibits the expression of TNF-α, IL-1β, and IL-6, demonstrating anti-inflammatory activity in a DSS-induced acute colitis model in mice.
Formula:C₁₆H₂₃N₃O₂S
Color and Shape:Solid
Molecular weight:321.44
Ref: TM-T203517
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ACTH (1-14)
CAS:
- 25696-21-3
ACTH (1-14) is a pituitary hormone fragment that controls cortisol and androgen levels.
Formula:C₇₇H₁₀₉N₂₁O₂₀S
Purity:98%
Color and Shape:Solid
Molecular weight:1680.88
Ref: TM-TP1238
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QWF acetate
QWF acetate is a Substance P antagonist peptide that specifically inhibits the binding to its receptor, NK1, and inhibits the activation of MRGPRX2.
Formula:C₄₀H₄₇N₅O₁₀
Purity:96.65%
Color and Shape:Solid
Molecular weight:757.84
Ref: TM-TP1946L
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PEN (human)
CAS:
- 597578-70-6
PEN (human) is an Endogenous peptide GPR83 agonist. ProSAAS-derived neuropeptide.
Formula:C₉₇H₁₅₉N₂₇O₃₂
Purity:98%
Color and Shape:Solid
Molecular weight:2215.49
Ref: TM-TP1949
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[D-Trp8]-γ-MSH
CAS:
- 321351-81-9
[D-Trp8]-γ-MSH is a selective melanocortin 3 (MC3) receptor agonist (IC50 values are 6.7, 340 and 600 nM for human MC3, MC5 and MC4 receptors respectively).
Formula:C₇₄H₉₉N₂₁O₁₆S
Purity:98%
Color and Shape:Solid
Molecular weight:1570.79
Ref: TM-TP1893
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HAEGTFT
CAS:
- 926018-95-3
HAEGTFT is the first N-terminal 1-7 residues of GLP-1 peptide.
Formula:C₃₃H₄₇N₉O₁₂
Purity:98%
Color and Shape:Solid
Molecular weight:761.78
Ref: TM-TP1419
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Neuropeptide Y5 receptor ligand-1
CAS:
- 322723-35-3
Neuropeptide Y5 receptor ligand-1 (Compound 54), a carbazole derivative, acts as a powerful antagonist to the neuropeptide Y5 (NPY-5) receptor [1].
Formula:C₁₉H₁₇N₃O₂
Color and Shape:Solid
Molecular weight:319.36
Ref: TM-T74654
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GB-110 hydrochloride
GB-110 HCl: potent, nonpeptidic oral PAR2 agonist; triggers Ca2+ release in HT29 cells; EC50 0.28 μM.
Formula:C₃₃H₄₉ClN₆O₅
Color and Shape:Solid
Molecular weight:645.23
Ref: TM-T73854
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Neuropeptide FF
CAS:
- 99566-27-5
Endogenous antiopioid peptide and agonist at NPFF1 and NPFF2 receptors (Ki values are 2.82 and 0.21 nM respectively).
Formula:C₅₄H₇₆N₁₄O₁₀
Purity:98%
Color and Shape:Solid
Molecular weight:1081.27
Ref: TM-TP1074
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d[Leu4,Lys8]-VP
CAS:
- 42061-33-6
Vasopressin V1B agonist; Ki: 0.16nM V1B, 64nM oxytocin; weak antidiuretic/vasopressor; minimal oxytocic action.
Formula:C₄₇H₆₇N₁₁O₁₁S₂
Purity:98%
Color and Shape:Solid
Molecular weight:1026.2
Ref: TM-TP1927
+ Info
ELA-32(human)
CAS:
- 1680205-79-1
Potent apelin receptor agonist with IC50 = 0.27 nM; does not bind GPR15/GPR25. Boosts hESC self-renewal and angiogenesis.
Formula:C₁₇₀H₂₈₉N₆₃O₃₉S₄
Purity:98%
Color and Shape:Solid
Molecular weight:3967.8
Ref: TM-TP2097
+ Info
Nadolol
CAS:
- 42200-33-9
Nadolol is a non-selective beta-adrenergic antagonist with antihypertensive and antiarrhythmic activities.
Formula:C₁₇H₂₇NO₄
Purity:99.87% - 99.92%
Color and Shape:White To Off-White Crystalline Powder Solid
Molecular weight:309.40
Ref: TM-T1203
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Ramelteon metabolite M-II
CAS:
- 896736-21-3
Ramelteon M-II binds MT1/MT2 with IC50s: 208/1470 pM; it's the main metabolite and a melatonin receptor agonist.
Formula:C₁₆H₂₁NO₃
Purity:98%
Color and Shape:Solid
Molecular weight:275.34
Ref: TM-T12689
+ Info
Linaclotide acetate
CAS:
- 851199-60-5
Linaclotide acetate, an oral guanylate cyclase C agonist with 14 amino acids, treats constipation-predominant IBS and chronic constipation.
Formula:C₆₁H₈₃N₁₅O₂₃S₆
Purity:98%
Color and Shape:Solid
Molecular weight:1586.79
Ref: TM-T11852L
+ Info
Meclinertant
CAS:
- 146362-70-1
Meclinertant: selective NTS1 antagonist, blocks Ca2+ mobilization, with anxiolytic and anti-addictive properties.
Formula:C₃₂H₃₁ClN₄O₅
Purity:97.51% - 99.44%
Color and Shape:Solid
Molecular weight:587.07
Ref: TM-T16034
+ Info
GRP (14-27) (human, porcine, canine)
CAS:
- 81608-29-9
GRP (14-27) (human, porcine, canine) functions as a ligand for bombesin receptors, with its specific binding being inhibited by GTP and GDP, while GMP does not
Formula:C₇₅H₁₁₀N₂₄O₁₆S₂
Purity:98%
Color and Shape:Solid
Molecular weight:1667.96
Ref: TM-T80148
+ Info
8-iso Prostaglandin E2
CAS:
- 27415-25-4
"8-iso PGE2: Isoprostane from arachidonic acid, potent rat renal vasoconstrictor, reduces GFR and renal flow by 80%, no BP effect."
Formula:C₂₀H₃₂O₅
Color and Shape:Solid
Molecular weight:352.47
Ref: TM-T36160
+ Info
Ac-(d-Arg)-CEH-(d-Phe)-RWC-NH2
CAS:
- 819048-44-7
Ac-DArg-c[Cys-Glu-His-DPhe-Arg-Trp-Cys]-NH2 is a synthetic cyclic octapeptide that exhibits melanocortin-4 receptor (MC4R) agonism and has been shown to
Formula:C₅₁H₇₀N₁₈O₁₁S₂
Purity:98%
Color and Shape:Solid
Molecular weight:1175.35
Ref: TM-T80121
+ Info
GLP-1R agonist 16
CAS:
- 2763329-13-9
Compound 115a, a GLP-1R agonist, effectively activates the GLP-1 receptor with an EC50 of 0.15 nM [1].
Formula:C₅₀H₅₈FN₁₀O₆P
Color and Shape:Solid
Molecular weight:945.03
Ref: TM-T74610
+ Info
Galanin Receptor Ligand M35
CAS:
- 142846-71-7
M35, a galanin(1-13)-bradykinin(2-9) amide, acts as a galanin antagonist in rats and inhibits mouse pancreatic islets.
Formula:C₁₀₇H₁₅₃N₂₇O₂₆
Purity:98%
Color and Shape:Solid
Molecular weight:2233.6
Ref: TM-TP1662
+ Info
GPR55 agonist 4
GPR55 agonist 4 (Compound 28), with an EC50 of 131 nM for hGPR55 and 1.41 nM for rGPR55, effectively induces β-arrestin recruitment to human GPR55 [1].
Formula:C₁₉H₁₆FN₅O₂
Color and Shape:Solid
Molecular weight:365.36
Ref: TM-T79744
+ Info
15(R)-17-phenyl trinor Prostaglandin F2α
CAS:
- 41639-71-8
17-phenyl trinor Prostaglandin F2α N-ethyl amide (17-phenyl trinor PGF2α) is an F-series prostaglandin analog which has been approved for use as an ocular
Formula:C₂₃H₃₂O₅
Color and Shape:Solid
Molecular weight:388.5
Ref: TM-T37930
+ Info
GLP-1R agonist 4
CAS:
- 2401894-26-4
GLP-1R agonist 4, potentially for diabetes research, is a potent GLP-1R stimulator linked to hypoglycemia.
Formula:C₃₂H₃₀ClF₂N₃O₅
Color and Shape:Solid
Molecular weight:610.05
Ref: TM-T74323
+ Info
L-803087 TFA
CAS:
- 1786412-46-1
L-803087 TFA: potent sst4 agonist, Ki=0.7 nM, >280x selective vs other somatostatin receptors; boosts AMPA, heightens seizures.
Formula:C₂₇H₃₀F₅N₅O₅
Color and Shape:Solid
Molecular weight:599.55
Ref: TM-T39207
+ Info
Sufotidine
CAS:
- 80343-63-1
Sufotidine (AH 25352X) is a highly selective competitive H2 receptor antagonist.
Formula:C₂₀H₃₁N₅O₃S
Purity:99.03% - 99.92%
Color and Shape:Solid
Molecular weight:421.56
Ref: TM-T68146
+ Info
Tamuzimod
CAS:
- 2097854-81-2
Tamuzimod, an effective immunomodulator, exhibits modulatory activity on S1P Receptors with EC50 values below 1 μM [1] [2].
Formula:C₂₁H₁₃Cl₃F₃N₅O₃
Color and Shape:Solid
Molecular weight:546.71
Ref: TM-T74747
+ Info
Ro60-0175
CAS:
- 169675-08-5
Ro60-0175 is a selective 5-HT2B and 5-HT2C serotonin receptor agonist, often used as fumarate.
Formula:C₁₁H₁₂ClFN₂
Purity:97.09%
Color and Shape:Solid
Molecular weight:226.68
Ref: TM-T39161
+ Info
LY 344864 racemate
CAS:
- 186543-64-6
LY 344864 racemate is a 5-HT1F receptor agonist.
Formula:C₂₁H₂₂FN₃O
Purity:99.75%
Color and Shape:Soild
Molecular weight:351.42
Ref: TM-T2344L
+ Info
HPP-9
HPP-9, a Proteolysis-Targeting Chimera (PROTAC) derived from Hedgehog Pathway Inhibitor-1 (HPI-1) with a pIC50 value of 6.71, is designed to degrade BET
Formula:C₄₉H₅₂N₆O₁₁
Color and Shape:Solid
Molecular weight:900.97
Ref: TM-T79907
+ Info
PROTAC(H-PGDS)-8
CAS:
- 2761281-51-8
PROTAC(H-PGDS)-8 is a PROTAC degrader targeting Hematopoietic prostaglandin D synthase (H-PGDS), exhibiting an IC50 of 0.14 μM [1].
Formula:C₄₁H₄₀N₈O₇
Color and Shape:Solid
Molecular weight:756.81
Ref: TM-T84924
+ Info
9-deoxy-9-methylene Prostaglandin E2
CAS:
- 61263-32-9
9-deoxy-9-methylene PGE2: stable PGE2 analog with similar effects, less side effects, equal potency in rats, gerbils, primates.
Formula:C₂₁H₃₄O₄
Color and Shape:Solid
Molecular weight:350.499
Ref: TM-T36728
+ Info
(-)-Eseroline fumarate
CAS:
- 70310-73-5
(-)-Eseroline fumarate, a Physostigmine metabolite and AChE inhibitor, triggers cancer cell LDH release and neuronal cell death.
Formula:C₁₇H₂₂N₂O₅
Color and Shape:Solid
Molecular weight:334.37
Ref: TM-T73930
+ Info
JNJ-40929837 succinate
CAS:
- 1191044-47-9
JNJ-40929837 succinate is a selective, orally active inhibitor of LTA 4 H (leukotriene A 4 hydrolase). This compound effectively inhibits aminopeptidase activity, leading to the accumulation of Pro-Gly-Pro in serum, and can be utilized in asthma research [1].
Formula:C₂₂H₂₄N₄O₂S·xC₄H₆O₄
Color and Shape:Solid
Ref: TM-T86771
+ Info
BIM-23190 hydrochloride
BIM-23190 hydrochloride, somatostatin analog, SSRT2/5 agonist, Ki: 0.34 nM (SSTR2), 11.1 nM (SSTR5). Used in cancer, acromegaly research.
Color and Shape:Liquid
Ref: TM-T37109
+ Info
HS024 TFA
HS024, a selective MC4 receptor antagonist, exhibits affinity with Ki values of 0.29, 3.29, 5.45, and 18.6 nM for MC4, MC5, MC3, and MC1 receptors, respectively
Formula:C₆₀H₈₀F₃N₁₉O₁₂S₂
Color and Shape:Solid
Molecular weight:1380.52
Ref: TM-T75852
+ Info
GLP-1(28-36)amide TFA
GLP-1(28-36)amide TFA, a nonapeptide cleavage product of GLP-1, shows antioxidant properties with anti-diabetic and cardioprotective effects.
Formula:C₅₆H₈₆F₃N₁₅O₁₁
Color and Shape:Solid
Molecular weight:1202.37
Ref: TM-T76191
+ Info
Tamsolusin Hydrochloride
CAS:
- 80223-99-0
Tamsolusin Hydrochloride (YM 12617) is a highly selective alpha-1A adrenergic receptor antagonist used in the treatment of benign prostatic hypertrophy.
Formula:C₂₀H₂₉ClN₂O₅S
Purity:99.92%
Color and Shape:Soild
Molecular weight:444.97
Ref: TM-T83965
+ Info
LH-RH (7-10)
CAS:
- 38482-71-2
LH-RH (7-10), a tetrapeptide, is a key LHRH degradation product found in macrophages and pneumocytes.
Formula:C₁₉H₃₆N₈O₄
Color and Shape:Solid
Molecular weight:440.54
Ref: TM-T76353
+ Info
SAR441255
SAR441255 is a potent unimolecular peptide that acts as a GLP-1/GIP/GCG receptor triagonist, demonstrating balanced activation across all three target receptors
Color and Shape:Odour Solid
Ref: TM-T81214
+ Info
Substance P (alligator)
CAS:
- 113516-47-5
Substance P from alligator: a neuropeptide with structure Arg-Pro-Arg-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2.
Formula:C₆₃H₉₈N₂₀O₁₃S
Color and Shape:Solid
Molecular weight:1375.64
Ref: TM-T76449
+ Info
Amylin, amide, human TFA
Amylin, a 37-amino acid human hormone, moderates glucose regulation by reducing glucagon, delaying digestion, and increasing satiety.
Formula:C₁₆₇H₂₆₂F₃N₅₁O₅₇S₂
Color and Shape:Solid
Molecular weight:4017.3
Ref: TM-T75787
+ Info
Pramlintide
CAS:
- 151126-32-8
Pramlintide, a polypeptide analog of human amylin, is an antidiabetic agent with antineoplastic properties in colorectal cancer.
Color and Shape:Solid
Ref: TM-T38998
+ Info
CCZ01048 TFA
CCZ01048 TFA, α-MSH analog, binds MC1R with 0.31 nM affinity, internalizes in melanoma cells, and is stable for melanoma PET imaging.
Formula:C₇₃H₁₀₆F₃N₂₁O₁₈
Color and Shape:Solid
Molecular weight:1622.75
Ref: TM-T76072L
+ Info
(Phe2,Orn8)-Oxytocin acetate
(Phe2,Orn8)-Oxytocin acetate: V1 agonist with EC50 of 280 nM for rabbit epididymis contractility.
Formula:C₄₄H₆₉N₁₃O₁₃S₂
Color and Shape:Solid
Molecular weight:1052.23
Ref: TM-T76630
+ Info
CART(55-102)(rat) TFA
Rat CART(55-102) TFA suppresses appetite, links to leptin/neuropeptide Y, and may induce anxiety/stress.
Formula:C₂₂₈H₃₆₈F₃N₆₅O₆₇S₇
Color and Shape:Solid
Molecular weight:5373.2
Ref: TM-T75900
+ Info
DOTA-JR11
CAS:
- 1039726-31-2
DOTA-JR11 is a somatostatin receptor 2 (SSTR2) antagonist that can be radiolabeled with 68Ga.
Formula:C₇₄H₉₈ClN₁₉O₂₁S₂
Color and Shape:Solid
Molecular weight:1689.27
Ref: TM-T80157
+ Info
Neuropeptide SF(mouse,rat) TFA
Neuropeptide SF TFA is a potent agonist for NPFF1 (Ki=48.4 nM) and NPFF2 (Ki=12.1 nM) and enhances ASIC3 current.
Formula:C₄₂H₆₆F₃N₁₃O₁₂
Color and Shape:Solid
Molecular weight:1002.05
Ref: TM-T75865
+ Info
Relamorelin TFA
CAS:
- 2863659-22-5
Relamorelin (RM-131) TFA: ghrelin analog, GHSR agonist, 0.42 nM affinity, boosts growth hormone, enhances gastric emptying, potential in motility disorders.
Formula:C₄₅H₅₁F₃N₈O₇S
Color and Shape:Solid
Molecular weight:905
Ref: TM-T75262
+ Info
Alsactide
CAS:
- 34765-96-3
Alsactide, an adrenocorticotropic hormone (ACTH) agonist and a heptadecapeptide analogue, is utilized in the study of the central nervous system [1].
Formula:C₉₉H₁₅₅N₂₉O₂₁S
Color and Shape:Solid
Molecular weight:2119.53
Ref: TM-T76297
+ Info
GLP-1(9-36)amide TFA
GLP-1(9-36)amide TFA, a DPP-4 metabolite of GLP-1(7-36) amide, antagonizes human pancreatic GLP-1 receptor.
Formula:C₁₄₂H₂₁₅F₃N₃₆O₄₅
Color and Shape:Solid
Molecular weight:3203.43
Ref: TM-T75822
+ Info
Adrenomedullin (16-31), human TFA
Human adrenomedullin (16-31) TFA, fragment 16-31, binds CGRP1 receptor, raises rat blood pressure, not cats’.
Formula:C₈₄H₁₃₀F₃N₂₅O₂₃S₂
Color and Shape:Solid
Molecular weight:1979.21
Ref: TM-T76011
+ Info
Angiopeptin TFA
CAS:
- 2478421-60-0
Angiopeptin TFA: somatostatin analogue, sst2/sst5 partial agonist (IC50: 0.26/6.92 nM), suppresses GH & IGF-1, for atherosclerosis research.
Formula:C₅₈H₇₃F₆N₁₁O₁₄S₂
Color and Shape:Solid
Molecular weight:1326.39
Ref: TM-T76042
+ Info
Amylin (8-37), human
CAS:
- 135702-23-7
Human-derived Amylin (8-37) is a vasodilator in rat arteries and forms aggregates linked to type II diabetes.
Formula:C₁₃₈H₂₁₆N₄₂O₄₅
Color and Shape:Solid
Molecular weight:3183.495
Ref: TM-T38764
+ Info
LCKLSL acetate
LCKLSL acetate is a potent AnxA2 inhibitor, blocking tPA binding and plasmin production, with anti-angiogenic effects.
Formula:C₃₂H₆₁N₇O₁₀S
Purity:99.9%
Color and Shape:Solid
Molecular weight:735.93
Ref: TM-TP2482
+ Info
Orexin B, rat, mouse TFA
Orexin B, rat/mouse TFA, activates OX1-R & OX2-R receptors, influencing food intake, energy, and sleep regulation.
Formula:C₁₂₈H₂₁₆F₃N₄₅O₃₆S
Color and Shape:Solid
Molecular weight:3050.42
Ref: TM-T75925
+ Info
PAMP-12 (unmodified)
CAS:
- 929905-12-4
PAMP-12 (unmodified), an endogenous peptide and potent MRGPRX2 (MrgX2) agonist (EC50=20-50 nM), induces hypotension by inhibiting catecholamine release from
Formula:C₇₇H₁₁₈N₂₄O₁₅
Color and Shape:Solid
Molecular weight:1619.91
Ref: TM-T78027
+ Info
Adrenotensin (human)
CAS:
- 166546-72-1
Adrenotensin: human 153-185 fragment of Adrenomedullin precursor, a 52-amino acid peptide in CGRP hormone family.
Formula:C₁₄₃H₂₂₄N₄₂O₄₃
Color and Shape:Solid
Molecular weight:3219.56
Ref: TM-T76473
+ Info
[Sar4] Substance P (4-11)
'[Sar4] Substance P (4-11) is a C-terminus fragment and agonist of Substance P.'
Formula:C₄₄H₆₅N₁₁O₁₀S
Color and Shape:Solid
Molecular weight:940.12
Ref: TM-T76483
+ Info
(D-Phe7)-α-MSH
CAS:
- 92937-43-4
(D-Phe7)-α-MSH is an α-MSH analogue [1] .
Formula:C₇₇H₁₀₉N₂₁O₁₉S
Color and Shape:Solid
Molecular weight:1664.88
Ref: TM-T76346
+ Info
Satoreotide
CAS:
- 1801415-23-5
Satoreotide (JR11) is an SSTR2 antagonist, typically conjugated with radiolabeled chelators for use in neuroendocrine tumor imaging [1].
Formula:C₅₈H₇₂ClN₁₅O₁₄S₂
Color and Shape:Solid
Molecular weight:1302.87
Ref: TM-TP2620
+ Info
GHRF, bovine
CAS:
- 88894-91-1
bGRF(1-44)-NH2 is a bovine GH-releasing factor that stimulates GH release and synergizes with Hydrocortisone.
Formula:C₂₂₀H₃₆₆N₇₂O₆₆S
Color and Shape:Solid
Molecular weight:5104.72
Ref: TM-T76325
+ Info
Fsh receptor-binding inhibitor fragment(bi-10)
CAS:
- 163973-98-6
FSH antagonist bi-10 suppresses ovulation, induces follicular atresia, and may help in ovarian cancer by downregulating FSHR/ERβ.
Formula:C₄₂H₆₇N₁₃O₁₉
Color and Shape:Solid
Molecular weight:1058.06
Ref: TM-T76566
+ Info
GLP-1R agonist 19
CAS:
- 2765065-09-4
GLP-1R agonist 19 (M3190) is a potent, selective GLP-1 receptor agonist that demonstrates excellent plasma and liver microsomal stability, along with low hERG toxicity [1].
Formula:C₉₄H₁₃₆FN₂₁O₂₅
Color and Shape:Solid
Molecular weight:1979.21
Ref: TM-T86507
+ Info
[Nle13]-Motilin
CAS:
- 55524-56-6
[Nle13]-Motilin, a motilin analogue, is a motilin receptor agonist [1] [2] .
Formula:C₁₂₁H₁₉₀N₃₄O₃₅
Color and Shape:Solid
Molecular weight:2681.01
Ref: TM-T76359
+ Info
ACTH (3-24) (human, bovine, mouse, ovine, porcine, rabbit, rat)
CAS:
- 1036763-00-4
ACTH (3-24) is the fragment 3-24 of ACTH, used in disease research including cancer and immune disorders.
Formula:C₁₂₄H₁₉₆N₃₈O₂₇S
Color and Shape:Solid
Molecular weight:2683.19
Ref: TM-T76500
+ Info
Ceruletide Ammonium Salt
Ceruletide Ammonium Salt is a decapeptide, originating from the skin of tropical frogs, which is a potent cholecystokinin receptor agonist and a safe and
Formula:C₅₈H₇₇N₁₄O₂₁S₂
Purity:98.47% - 98.54%
Color and Shape:Soild
Molecular weight:1370.44
Ref: TM-T14932L1
+ Info
Galanin (1-13)-Neuropeptide Y (25-36) amide
CAS:
- 147138-51-0
Galanin (1-13)-Neuropeptide Y (25-36) amide exhibits high-affinity binding to galanin receptors, similar to that of galanin itself [1].
Formula:C₁₃₆H₂₀₉N₄₁O₃₄
Purity:98%
Color and Shape:Solid
Molecular weight:2962.37
Ref: TM-T80143
+ Info
Tezusomant
CAS:
- 2802416-72-2
Tezusomant is an antagonist of the growth hormone receptor (growth hormone receptor). It is being investigated for potential use in conditions like acromegaly, which are caused by excessive secretion of growth hormone.
Formula:C₁₂₀H₁₇₁N₂₃O₃₂S
Color and Shape:Solid
Molecular weight:2479.84
Ref: TM-T207171
+ Info
CB2R/FAAH modulator-2
CAS:
- 2876918-68-0
CB2R/FAAH modulator-2 (compound 26) is a dual modulator targeting at CB2R and FAAH.
Formula:C₂₄H₃₃NO₂
Purity:99.15%
Color and Shape:Soild
Molecular weight:367.52
Ref: TM-T67745
+ Info
SphK1&2-IN-1
CAS:
- 1415662-57-5
SphK1&2-IN-1 is a sphingosine kinase inhibitor with anti-inflammatory, antitumor and hemostatic effects.
Formula:C₁₄H₁₄N₂O₃S
Purity:99.59%
Color and Shape:Solid
Molecular weight:290.34
Ref: TM-T9992
+ Info
Kisspeptin 13
CAS:
- 374675-18-0
Kisspeptin 13 activates GPR54 & GnRH receptors, boosts memory, and aids in Alzheimer's research.
Formula:C₇₈H₁₀₇N₂₁O₁₈
Color and Shape:Solid
Molecular weight:1626.81
Ref: TM-T76339
+ Info
Methionyl-Lysyl-Bradykinin
CAS:
- 550-19-6
Methionyl-Lysyl-Bradykinin (Met-Lys-Bradykinin), a Bradykinin analogue, is a kinin [1] [2] .
Formula:C₆₁H₉₄N₁₈O₁₃S
Color and Shape:Solid
Molecular weight:1319.58
Ref: TM-T76384
+ Info
YFLLRNP
CAS:
- 149440-16-4
YFLLRNP is a biologically active peptide functioning as a partial agonist of PAR-1, selectively activating the G12/13 signaling pathway.
Formula:C₄₅H₆₇N₁₁O₁₀
Color and Shape:Solid
Molecular weight:922.08
Ref: TM-T80235
+ Info
Parstatin(human) TFA
Parstatin(human) TFA, a cell-penetrating PAR-1 thrombin receptor agonist peptide, effectively inhibits angiogenesis, as indicated by studies [1] [2].
Formula:C₁₉₃H₃₃₁F₃N₆₄O₅₅S₃
Color and Shape:Solid
Molecular weight:4581.28
Ref: TM-T75873
+ Info
Urocortin II, mouse
CAS:
- 330648-32-3
Mouse Urocortin II: Selective CRF2 agonist, Ki 0.66 nM for CRFR2, >100 nM for CRFR1, affects central neural circuits.
Formula:C₁₈₇H₃₂₀N₅₆O₅₀
Color and Shape:Solid
Molecular weight:4152.96
Ref: TM-T76127
+ Info
PAR 4 (1-6) (TFA)
PAR 4 (1-6) TFA (GYPGQV TFA), a hexapeptide derived from protease-activated receptor 4 (PAR 4), serves as a specific agonist for PAR 4.
Formula:C₂₈H₄₁N₇O₉·xC₂HF₃O₂
Color and Shape:Solid
Ref: TM-T75904
+ Info
Dolcanatide
CAS:
- 1092457-65-2
Dolcanatide: oral GC-C agonist with laxative, pain-relief, and anti-inflammatory properties for IBD research.
Formula:C₆₅H₁₀₄N₁₈O₂₆S₄
Color and Shape:Solid
Molecular weight:1681.89
Ref: TM-T76274
+ Info
TRAP-6 amide TFA
CAS:
- 1426807-16-0
TRAP-6 amide TFA is a PAR-1 thrombin receptor agonist peptide.
Formula:C₃₆H₅₈F₃N₁₁O₁₀
Color and Shape:Solid
Molecular weight:861.922
Ref: TM-T38887
+ Info
Ala5-Galanin (2-11)
CAS:
- 859843-84-8
Ala5-Galanin (2-11) is a specific agonist for the galanin receptor 2 (GAL2R) with an affinity constant (Ki) of 258 nM [1].
Formula:C₅₄H₈₁N₁₃O₁₃
Purity:98%
Color and Shape:Solid
Molecular weight:1120.3
Ref: TM-T80517
+ Info
Stressin I
Potent CRF1 agonist; Ki: 1.5 nM (CRF1), 224 nM (CRF2). Boosts ACTH, enhances stool frequency after i.p. administration.
Formula:C₂₀₃H₃₃₇N₅₇O₅₆
Purity:98%
Color and Shape:Solid
Molecular weight:4472.24
Ref: TM-TP2125
+ Info
Des His1, Glu8 Exendin-4
Des His1, Glu8 Exendin-4 is a glucagon-like peptide-1 receptor (GLP1R) antagonist that regulates blood glucose and is used in the study of diabetes and obesity.
Formula:C₁₇₉H₂₇₇N₄₇O₅₉S
Purity:99.92%
Color and Shape:Solid
Molecular weight:4063.46
Ref: TM-T76291
+ Info
Val9-Oxytocin
CAS:
- 1021701-88-1
Val9-Oxytocin, an Oxytocin analog where Gly9 is substituted with Val9 [1], functions as a complete antagonist of the vasopressin (V1a) receptor.
Formula:C₄₆H₇₂N₁₂O₁₂S₂
Purity:98%
Color and Shape:Solid
Molecular weight:1049.27
Ref: TM-T80136
+ Info
Palmitoyl tetrapeptide-20 TFA
Palmitoyl tetrapeptide-20 (PTP20) TFA is a biomimetic peptide and acts as an agonist of α-MSH. It protects follicular melanocytes by boosting catalase expression and activating melanogenesis.
Formula:C₃₈H₇₀N₆O₈·xC₂HF₃O₂
Ref: TM-TP3504
+ Info
BPP-2
BPP-2 is a GHSR ligand containing the element F. By labeling BPP-2 with the isotope 18F, a PET probe targeting GHSR can be produced. The binding affinity (Ki) of 18F-BPP-2 for GHSR is 274 nM.
Formula:C₂₇H₂₈FN₅O₂
Molecular weight:473.2227
Ref: TM-T209024
+ Info
[Leu13]-Motilin
CAS:
- 59530-69-7
[Leu13]-Motilin (KW-5139) is an analogue of the gastrointestinal hormone motilin that induces concentration-dependent contractions in rabbit gastrointestinal
Formula:C₁₂₁H₁₉₀N₃₄O₃₅
Purity:98%
Color and Shape:Solid
Molecular weight:2681.01
Ref: TM-T78563
+ Info
GLP-1R agonist 20
GLP-1R agonist 20 (Compound I-132) is an agonist of the glucagon-like peptide-1 receptor (GLP-1 receptor), with an EC50 value of 0.0162 nM.
Formula:C₃₁H₃₀Cl₂F₂N₄O₅
Molecular weight:646.15613
Ref: TM-T209770
+ Info
palm11-PrRP31
Palm11-PrRP31 is a lipid-modified analog of the endogenous appetite-suppressing neuropeptide (PrRP). It functions as a potent dual agonist for GPR10 (EC50 = 39 pM) and NPFF-R2. By mimicking the natural activity of PrRP, palm11-PrRP31 binds to these receptors to reduce food intake. It has potential applications as an anti-obesity agent and is useful in studying neuropeptide and receptor interactions.
Formula:C₁₈₁H₂₈₉N₅₅O₄₆S
Molecular weight:4001.16865
Ref: TM-TP3581
+ Info
SPN009
SPN009 (Sequence 3) is a GLP-1 receptor (GLP-1 Receptor) agonist, with an EC50 of 2.84 nM, and improves type 2 diabetes in DB/DB mouse models.
Formula:C₁₉₁H₂₉₉N₄₅O₅₉
Molecular weight:4167.17798
Ref: TM-TP3525
+ Info
A 77636 hydrochloride
CAS:
- 145307-34-2
A 77636 hydrochloride is a potent, orally active, selective and long acting dopamine D1 receptor agonist (pKi=7.40; Ki=39.8 nM).
Formula:C₂₀H₂₈ClNO₃
Purity:99.57%
Color and Shape:Solid
Molecular weight:365.89
Ref: TM-T21782
+ Info
[D-Trp34]-Neuropeptide Y Acetate
[D-Trp34]-Neuropeptide Y Acetate is a potent Y5 receptor agonist that increases rat food intake; less potent at Y1, Y2, Y4, Y6.
Formula:C₁₉₈H₂₉₃N₅₅O₅₈
Purity:99.73%
Color and Shape:Soild
Molecular weight:4371.78
Ref: TM-TP1984L
+ Info
Cafelkibart
Cafelkibart is a chimeric IgG1κ monoclonal antibody targeting CCR8, with HumanIgG1kappa, Isotype Control serving as its corresponding isotype control.
Color and Shape:Odour Liquid
Ref: TM-T9901A-351
+ Info
Wy 43657
CAS:
- 78255-70-6
Wy 43657 is a gonadorelin antagonist.
Formula:C₇₁H₈₆N₁₄O₁₃
Purity:98%
Color and Shape:Solid
Molecular weight:1343.554
Ref: TM-T26337
+ Info
Uroguanylin (human)
CAS:
- 154525-25-4
Uroguanylin (human) serves as a natural ligand for the Guanylyl Cyclase C (GCC) receptor in metastatic colorectal cancer tumors and exhibits anti-tumor effects
Formula:C₆₄H₁₀₂N₁₈O₂₆S₄
Purity:98%
Color and Shape:Solid
Molecular weight:1667.86
Ref: TM-T80067
+ Info
APTAA-LHRH
CAS:
- 83539-08-6
APTAA-LHRH is a gonadorelin antagonist.
Formula:C₆₉H₉₁Cl₂N₁₇O₁₄
Purity:98%
Color and Shape:Solid
Molecular weight:1453.47
Ref: TM-T25105
+ Info
Kadsurenin B
CAS:
- 145701-13-9
Kadsurenin B, a platelet-activating factor (PAF) antagonist, exhibits neuroprotective properties and has a broad spectrum of pharmacological research
Formula:C₂₀H₂₂O₅
Color and Shape:Solid
Molecular weight:342.39
Ref: TM-T79948
+ Info
U 67827E
CAS:
- 103494-23-1
U 67827E is a long-lasting cholecystokinin agonist. It acts by decreases food intake.
Formula:C₅₃H₆₈N₁₀O₁₇S
Purity:98%
Color and Shape:Solid
Molecular weight:1149.24
Ref: TM-T26305
+ Info
AA 497 HCl
CAS:
- 65860-38-0
AA 497, a beta-2 agonist, suppresses Ca spikes.
Formula:C₁₄H₂₂ClNO₃
Color and Shape:Solid
Molecular weight:287.78
Ref: TM-T26359L
+ Info
Anticancer agent 258
CAS:
- 2891984-12-4
Anticanceragent 258 is an imidazo[1,2-B][1,2,4]triazole derivative that modulates nuclear receptor activity. It exhibits an EC50 of 63 nM for Nurr in N2A cells and an IC50 of 0.1 pM for Nur77 in HEK293 cells. Anticanceragent 258 is applicable in studies related to cancer, metabolic disorders, and neurological diseases.
Formula:C₁₇H₁₂F₂N₄
Color and Shape:Solid
Molecular weight:310.3
Ref: TM-T203128
+ Info
Azaline
CAS:
- 134457-26-4
Azaline is a gonadorelin antagonist.
Formula:C₇₄H₁₀₆ClN₂₃O₁₂
Purity:98%
Color and Shape:Solid
Molecular weight:1545.26
Ref: TM-T25129
+ Info
Prolactin Releasing Peptide (1-31), human
CAS:
- 215510-22-8
Human Prolactin Releasing Peptide (1-31) is a potent GPR10 agonist; Ki values are 1.03 nM (human) and 0.33 nM (rat).
Formula:C₁₆₀H₂₅₂N₅₆O₄₂S
Purity:98%
Color and Shape:Solid
Molecular weight:3664.15
Ref: TM-TP1769
+ Info
(d(CH2)51,Tyr(Me)2,Arg8)-Vasopressin
CAS:
- 73168-24-8
V1A receptor antagonist; blocks vasopressin & oxytocin, lowers Ca²⁺ levels (IC50: 5/30 nM); long-acting antivasopressor; anxiolytic in dorsal hippocampus.
Formula:C₅₂H₇₄N₁₄O₁₂S₂
Purity:98%
Color and Shape:White Lyophilized Powder
Molecular weight:1151.38
Ref: TM-TP2136
+ Info
A-286501
CAS:
- 483341-15-7
A-286501: Oral adenosine kinase inhibitor, IC50=0.47 nM, reduces pain via non-opioid, non-NSAID ADO receptors.
Formula:C₁₁H₁₄BrN₅O₂
Purity:98%
Color and Shape:Solid
Molecular weight:328.17
Ref: TM-T26475
+ Info
LY 293284
CAS:
- 141318-62-9
LY 293284 is a potent, selective full agonist of 5-HT1A receptor with anxiogenic effects in animal studies.
Formula:C₁₉H₂₆N₂O
Color and Shape:Solid
Molecular weight:298.42
Ref: TM-T27914
+ Info
Jmv 176
CAS:
- 119068-32-5
Jmv 176 is a CCK agonist when first given and becomes a cholecystokinin antagonist after 3-4 hours.
Formula:C₅₃H₇₀N₈O₁₅S
Purity:98%
Color and Shape:Solid
Molecular weight:1091.24
Ref: TM-T25550
+ Info
Tiaspirone hydrochloride
CAS:
- 87691-92-7
Tiaspirone hydrochloride (BMY-13859 hydrochloride) exhibits antipsychotic activity and influences the electrophysiological activity of dopaminergic neurons.
Formula:C₂₄H₃₃ClN₄O₂S
Purity:99.87%
Color and Shape:Soild
Molecular weight:477.06
Ref: TM-T24885L
+ Info
Zicronapine fumarate
CAS:
- 170381-17-6
Zicronapine fumarate, an antipsychotic, targets D1/D2 & 5-HT2A receptors; may treat neuropsychiatric conditions.
Formula:C₂₆H₃₁ClN₂O₄
Color and Shape:Solid
Molecular weight:470.99
Ref: TM-T74668
+ Info
Ghrelin receptor full agonist-2
CAS:
- 2602452-73-1
Ghrelin receptor full agonist-2 is a highly potent Ghrelin receptor full agonist.
Formula:C₂₆H₂₈ClN₅O₅S
Color and Shape:Solid
Molecular weight:558.05
Ref: TM-T40234
+ Info
20-Carboxy-Leukotriene B4
CAS:
- 80434-82-8
20-COOH LTB4, a metabolite of LTB4, binds BLT1 receptor and inhibits LTB4-induced neutrophil responses.
Formula:C₂₀H₃₀O₆
Color and Shape:Solid
Molecular weight:366.45
Ref: TM-T73793
+ Info
Nα-Methylhistamine FA
Nα-Methylhistamine FA is a histamine H3 receptor agonist
Formula:C₇H₁₃N₃O₂
Purity:>99.99%
Color and Shape:Solid
Molecular weight:171.2
Ref: TM-T23038L
+ Info
TAK-448 acetate
CAS:
- 1470374-22-1
TAK-448 acetate (MVT-602 acetate) is a KISS1R agonist, a synthetic peptide similar to kisspeptin.
Formula:C₆₀H₈₄N₁₆O₁₆
Purity:99.88%
Color and Shape:Solid
Molecular weight:1285.41
Ref: TM-TP1093
+ Info
Pneumadin, rat
CAS:
- 130918-90-0
Rat Pneumadin (PNM), a decapeptide, stimulates AVP release, exerting strong antidiuretic effects in animals with an active AVP system.
Formula:C₄₇H₇₄N₁₂O₁₅
Purity:98%
Color and Shape:Solid
Molecular weight:1047.178
Ref: TM-T16553
+ Info
BAY-6672 hydrochloride
CAS:
- 2247520-31-4
BAY-6672 hydrochloride is a potent, selective antagonist of the human Prostaglandin F (FP) receptor, exhibiting an IC50 value of 11 nM.
Formula:C₂₆H₂₈BrCl₂N₃O₃
Color and Shape:Solid
Molecular weight:581.33
Ref: TM-T74213
+ Info
TGR5 agonist 1
Compound 18 (TGR5 agonist 1) is a potent agonist of TGR5, exhibiting an EC50 value of 0.31 µM [1].
Formula:C₂₈H₄₈NNaO₆S
Color and Shape:Solid
Molecular weight:549.74
Ref: TM-T74824
+ Info
Phoenixin-14
CAS:
- 1415039-79-0
Phoenixin-14 (PNX-14), an active endogenous isoform, induces an anxiolytic effect by activating the AHA GnRH system in mice and protects against ischemia/
Formula:C₇₅H₁₁₀N₁₈O₂₀
Purity:98%
Color and Shape:Solid
Molecular weight:1583.78
Ref: TM-T80422
+ Info
PACAP-38 (31-38), human, mouse, rat acetate
PACAP-38 (31-38) acetate stimulates PAC1 receptor and boosts NPY and catecholamine in sympathetic neurons.
Formula:C₄₉H₈₇N₁₇O₁₃
Purity:99.92%
Color and Shape:Solid
Molecular weight:1122.32
Ref: TM-TP1618L
+ Info
TLX agonist 2
TLX agonist 2 (compound 31) is a TLX agonist with an EC50 of 0.1 μM and a Kd of 0.16 μM. This compound enhances transcriptional activity by binding to TLX, thereby boosting the expression of TLX target genes. TLX agonist 2 is utilized in research on neurodegenerative diseases.
Color and Shape:Odour Solid
Ref: TM-T200680
+ Info
Lys-[Des-Arg9]Bradykinin
CAS:
- 71800-36-7
Selective bradykinin B1 agonist with Ki 0.12 nM; inactive at B2 (>30,000 nM). Lowers blood pressure, more potent than Des-Arg9-Bradykinin.
Formula:C₅₀H₇₃N₁₃O₁₁
Purity:98%
Color and Shape:Solid
Molecular weight:1032.21
Ref: TM-TP1918
+ Info
LTB4-IN-2
LTB4-IN-2 (Compound 6x) is a selective inhibitor of Leukotriene B4 (LTB4), acting by specifically targeting the 5-Lipoxygenase-activating protein (FLAP) with an
Formula:C₂₄H₁₇N₅S₂
Purity:98%
Color and Shape:Solid
Molecular weight:439.56
Ref: TM-T79389
+ Info
TGR5 agonist 6
CAS:
- 2925211-47-6
Compound 22b, also known as TGR5 agonist 6, is a non-systemic, intestine-targeted TGR5 agonist that demonstrates significant and sustained blood glucose-lowering effects with an acceptable safety profile.
Formula:C₄₂H₄₈Cl₂N₆O₆
Color and Shape:Solid
Molecular weight:803.77
Ref: TM-T200705
+ Info
Khusimol
CAS:
- 16223-63-5
Khusimol is a vasopressin V1a receptors non-peptide ligand that acts by inhibiting the binding of vasopressin.
Formula:C₁₅H₂₄O
Purity:98%
Color and Shape:Solid
Molecular weight:220.35
Ref: TM-T25577
+ Info
CB2R agonist 2
CB2R agonist 2 (cis-17-para) is a CB2R agonist [1].
Purity:98%
Color and Shape:Odour Solid
Ref: TM-T82770
+ Info
RC-3095
CAS:
- 138147-78-1
RC-3095, a selective GRPR antagonist, has been shown to have anti-inflammatory properties in different models of inflammation.
Formula:C₅₆H₇₉N₁₅O₉
Purity:98%
Color and Shape:Solid
Molecular weight:1106.32
Ref: TM-TP1470
+ Info
Sigma-1 receptor antagonist 5
Sigma-1 receptor antagonist 5 (compound 12), a 4-pyridylpiperidine derivative, exhibits analgesic properties through its antagonistic action on sigma receptors
Formula:C₂₆H₂₇N₃O
Purity:98%
Color and Shape:Solid
Molecular weight:397.51
Ref: TM-T78734
+ Info
Bay 55-9837
CAS:
- 463930-25-8
Selective VPAC2 agonist; EC50: 0.4 nM (VPAC2), 100 nM (VPAC1), >1000 nM (PAC1). Enhances insulin secretion, reduces HIV-1 replication.
Formula:C₁₆₇H₂₇₀N₅₂O₄₆
Purity:98%
Color and Shape:Solid
Molecular weight:3742.29
Ref: TM-TP2071
+ Info
Galanin-Like Peptide (rat)
CAS:
- 245114-97-0
Galanin-Like Peptide (rat), a neuropeptide comprising 60 amino acids, plays a crucial role in regulating feeding, body weight, and energy metabolism [1].
Formula:C₂₈₈H₄₆₁N₈₇O₈₃S
Purity:98%
Color and Shape:Solid
Molecular weight:6502.34
Ref: TM-T80146
+ Info
PSB-1114 triethylamine
PSB-1114 triethylamine is a potent, enzymatically stable, P2Y2 receptor agonist with a 134 nM EC50, exhibiting greater than 50-fold selectivity over P2Y4 (EC50
Formula:C₁₀H₁₅F₂N₃O₁₃P₃S·xC₆H₁₅N
Purity:98%
Color and Shape:Solid
Ref: TM-T78080
+ Info
Ro 25-1553
CAS:
- 159427-08-4
Ro 25-1553 is a 31-amino acid analog of vasoactive intestinal peptide (VIP) that functions as an agonist for the VIP2 receptor (VPAC2 receptor). In guinea pig models, Ro 25-1553 exhibits bronchodilator effects on tracheal smooth muscle contraction induced by neural stimuli or Carbachol.
Formula:C₁₆₀H₂₅₈N₄₆O₄₆
Color and Shape:Solid
Molecular weight:3562.04
Ref: TM-T203230
+ Info
Clotizolam
CAS:
- 54123-06-7
Clotizolam is a thienotriazolodiazepine derivative with PAF antagonistic properties, exhibiting sedative, anxiolytic, anticonvulsant, and muscle relaxant effects.
Formula:C₁₅H₁₀Cl₂N₄S
Color and Shape:Solid
Molecular weight:349.24
Ref: TM-T203541
+ Info
TGR5 agonist 7
TGR5 agonist 7 (Compound 22-Na) is an intestine-restricted, orally active agonist of the G protein-coupled bile acid receptor TGR5 (GPBAR1 or GPR131) with an EC50 of less than 1 μM. In mouse models, it demonstrates blood glucose-lowering effects, making it useful for diabetes research.
Formula:C₃₇H₅₉N₂NaO₉S
Color and Shape:Solid
Molecular weight:730.93
Ref: TM-T203565
+ Info
Adrogolide HCl
CAS:
- 166591-11-3
Adrogolide Hydrochloride is a selective dopamine receptor D1 agonist.
Formula:C₂₂H₂₆ClNO₄S
Color and Shape:Solid
Molecular weight:435.96
Ref: TM-T29674
+ Info
Halometasone
CAS:
- 50629-82-8
Halometasone: synthetic corticosteroid for psoriasis and eczema treatment.
Formula:C₂₂H₂₇ClF₂O₅
Color and Shape:Solid
Molecular weight:444.9
Ref: TM-T36379
+ Info
ent-Prostaglandin E2
CAS:
- 65085-69-0
Enzymatic PGE2 is optically pure; radical peroxidation makes it racemic. In oxidative stress, rac-PGE2 forms via 15-E2t-isoprostane.
Formula:C₂₀H₃₂O₅
Color and Shape:Solid
Molecular weight:352.471
Ref: TM-T35991
+ Info
17-trifluoromethylphenyl trinor Prostaglandin F2α ethyl amide
CAS:
- 1621369-73-0
Prostaglandin F2α (PGF2α), acting through the FP receptor, causes smooth muscle contraction and exhibits potent luteolytic activity.
Formula:C₂₆H₃₆F₃NO₄
Color and Shape:Solid
Molecular weight:483.572
Ref: TM-T37777
+ Info
Nolomirole
CAS:
- 90060-42-7
Nolomirole is a dopamine receptor agonist that reduces symptoms of congestive heart failure caused by monoclinine.
Formula:C₁₉H₂₇NO₄
Color and Shape:Solid
Molecular weight:333.42
Ref: TM-T33711
+ Info
GW-328267
CAS:
- 210237-78-8
GW-328267 is an agonist of the adenosine A2 receptor.
Formula:C₂₁H₂₆N₁₀O₄
Color and Shape:Solid
Molecular weight:482.5
Ref: TM-T24120
+ Info
Carazolol-d7
CAS:
- 1173021-02-7
Carazolol-d7 is the deuterium-labeled isotope of Carazolol, commonly used in pharmacokinetic studies to investigate the metabolic pathways of Carazolol.
Formula:C₁₈H₂₂N₂O₂
Color and Shape:Solid
Molecular weight:305.42
Ref: TM-T203713
+ Info
MMC(TMZ)-TOC TFA
MMC(TMZ)-TOC TFA exhibits high binding affinity and selectivity for the somatostatin receptor subtype 2 (SSTR2). It targets the delivery of TMZ to SSTR2-positive tumor cells, making MMC(TMZ)-TOC TFA useful for cancer research.
Formula:C₇₄H₉₉F₃N₂₀O₂₁S₂
Color and Shape:Solid
Molecular weight:1725.82
Ref: TM-T204151
+ Info
LysoPalloT-NH-amide-C3-ph-m-O-C11
CAS:
- 1778686-61-5
LysoPalloT-NH-amide-C3-ph-m-O-C11 is an agonist of the GPR174 receptor with an EC50 value of 34 nM.
Formula:C₂₇H₄₇N₂O₉P
Color and Shape:Solid
Molecular weight:574.64
Ref: TM-T203412
+ Info
α-CGRP (mouse, rat) TFA
α-CGRP (mouse, rat) TFA, a neuropeptide belonging to the calcitonin gene-related peptide (CGRP) family, is predominantly located at neuromuscular junctions and
Formula:C₁₆₂H₂₆₂N₅₀O₅₂S₂·C₂HF₃O₂
Purity:98%
Color and Shape:Solid
Ref: TM-T78540
+ Info
Antisauvagine-30 TFA
aSvg-30 TFA: potent CRF2 receptor antagonist, Kd 1.4 nM (mCRFR2β), 150 nM (CRFR1).
Formula:C₁₆₃H₂₇₅N₄₈F₃O₄₉S
Color and Shape:Solid
Molecular weight:3764.28
Ref: TM-T75805
+ Info
Nesiritide
CAS:
- 124584-08-3
Nesiritide, recombinant human B-type natriuretic peptide, binds NPR-A/C with Kd 7.3/13 pM.
Formula:C₁₄₃H₂₄₄N₅₀O₄₂S₄
Purity:98%
Color and Shape:Solid
Molecular weight:3464.04
Ref: TM-TP1208
+ Info
Fpl 14294
CAS:
- 154132-95-3
Fpl 14294 is a novel CCK-8 agonist with effective intranasal anorectic activity in the rat.
Formula:C₄₅H₅₆N₈O₁₃S₃
Purity:98%
Color and Shape:Solid
Molecular weight:1013.17
Ref: TM-T25437
+ Info
Velmupressin acetate
CAS:
- 1647120-04-4
Potent, selective, short-acting peptidic V2R agonist; EC50: 0.07 nM (hV2R), 0.02 nM (rV2R).
Formula:C₄₄H₆₄ClN₁₁O₁₀S₂
Purity:98%
Color and Shape:Solid
Molecular weight:1006.63
Ref: TM-TP1205
+ Info
(±)12-HEPE
CAS:
- 81187-21-5
(±)12-HEPE is produced by non-enzymatic oxidation of EPA.
Formula:C₂₀H₃₀O₃
Color and Shape:Solid
Molecular weight:318.457
Ref: TM-T35506
+ Info
AL12180
CAS:
- 748816-43-5
AL12180 is a bioactive chemical.
Formula:C₂₁H₂₇ClO₆
Color and Shape:Solid
Molecular weight:410.89
Ref: TM-T29810
+ Info
Substance P, Free Acid
CAS:
- 71977-09-8
Substance P, Free Acid is a synthetic analog of native Substance P, however, it lacks the biological activity exhibited by Substance P.
Formula:C₆₃H₉₇N₁₇O₁₄S
Purity:98%
Color and Shape:Solid
Molecular weight:1348.61
Ref: TM-TP1788
+ Info
(+)-Cloprostenol sodium
CAS:
- 62561-03-9
Cloprostenol sodium is a water-soluble PGF2α analog and FP receptor agonist, promoting luteolysis in rats and hamsters.
Formula:C₂₂H₂₈ClNaO₆
Color and Shape:Solid
Molecular weight:446.9
Ref: TM-T29245
+ Info
Secretoneurin, rat
CAS:
- 149146-12-3
Secretoneurin, rat, a 33-amino acid polypeptide, is generated by proteolytic processing of secretogranin II (SgII).
Formula:C₁₅₉H₂₅₂N₄₀O₅₈
Purity:98%
Color and Shape:Solid
Molecular weight:3651.95
Ref: TM-TP1597
+ Info
ORG 2766
CAS:
- 50913-82-1
ORG 2766 is an ACTH 4-9 (H-Met(O)-Glu-His-Phe-D-Lys-Phe-OH) analog and neurotrophic peptide.
Formula:C₄₀H₅₅N₉O₁₁S
Color and Shape:Solid
Molecular weight:869.99
Ref: TM-T33820
+ Info
Endothelin-3, human, mouse, rabbit, rat
CAS:
- 117399-93-6
Endothelin-3, human, mouse, rabbit, rat , is a cyclic 21 amino acid peptide. It is an endogenous neuropeptide and potent vasoconstrictor.
Formula:C₁₂₁H₁₆₈N₂₆O₃₃S₄
Purity:98%
Color and Shape:Solid
Molecular weight:2643.04
Ref: TM-TP1175
+ Info
(±)14(15)-EpETE
CAS:
- 131339-24-7
(±)14(15)-EpETE is an intestinal microbial lipid metabolite that attenuates cisplatin chemotherapy-induced nausea in rats by inhibiting Substance P release.
Formula:C₂₀H₃₀O₃
Color and Shape:Solid
Molecular weight:318.45
Ref: TM-T37234
+ Info
SAG dihydrochloride
CAS:
- 2702366-44-5
SAG dihydrochloride: potent Smo agonist, activates Hedgehog pathway, counters Cyclopamine. EC50=3 nM, Kd=59 nM.
Formula:C₂₈H₃₀Cl₃N₃OS
Purity:>99.99%
Color and Shape:Soild
Molecular weight:562.98
Ref: TM-T40465
+ Info
Nizatidine
CAS:
- 76963-41-2
Nizatidine (Acinon) is a competitive and reversible histamine H2-receptor antagonist with antacid activity.
Formula:C₁₂H₂₁N₅O₂S₂
Purity:99.43%
Color and Shape:White To Off-White Crystalline Powder
Molecular weight:331.46
Ref: TM-T1575
+ Info
GV-150013X
CAS:
- 151386-96-8
GV-150013X ((S)-1-(1-(adamantan-1-ylmethyl)-2,4-dioxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepin-3-yl)-3-phenylurea) is a potent CCKB antiagonist, pKi
Formula:C₃₃H₃₄N₄O₃
Purity:99.94%
Color and Shape:Soild
Molecular weight:534.65
Ref: TM-T27503L