GPCR/G-Protein
GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.
Subcategories of "GPCR/G-Protein"
- 5-HT Receptor(942 products)
- Adenosine Receptor(242 products)
- Adrenergic Receptor(2,949 products)
- Bombesin Receptor(30 products)
- Bradykinin Receptor(59 products)
- CXCR(149 products)
- CaSR(32 products)
- Cannabinoid Receptor(195 products)
- Dopamine Receptor(410 products)
- Endothelin Receptor(75 products)
- GNRH Receptor(73 products)
- GPCR19(31 products)
- GRK(32 products)
- GTPase(21 products)
- Glucagon Receptor(166 products)
- Hedgehog/Smoothened(45 products)
- Histamine Receptor(359 products)
- LPA Receptor(21 products)
- Melatonin Receptor(24 products)
- OX Receptor(40 products)
- Opioid Receptor(298 products)
- PAFR(11 products)
- PKA(49 products)
- S1P Receptor(17 products)
- SGLT(30 products)
- Sigma receptor(46 products)
Show 18 more subcategories
Found 5378 products of "GPCR/G-Protein"
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Chlorprothixene hydrochloride
CAS:Chlorprothixene hydrochloride, a typical antipsychotic, blocks 5-HT2, D1-D3, H1, muscarinic, and alpha1 receptors.Formula:C18H18ClNS·HClPurity:99.76%Color and Shape:White PowderMolecular weight:352.32Trazodone hydrochloride
CAS:<p>Trazodone hydrochloride (Trazodone HCl) is a serotonin uptake inhibitor that is used as an antidepressive agent.</p>Formula:C19H23Cl2N5OPurity:99.5% - 99.52%Color and Shape:SolidMolecular weight:408.33Antazoline hydrochloride
CAS:<p>Antazoline hydrochloride (Phenazoline hydrochloride), a first-generation antihistamine, can bind to the histamine H1 receptor and block the action of endogenous</p>Formula:C17H19N3·HClPurity:98% - 99.53%Color and Shape:White Or Almost White Crystalline PowderMolecular weight:301.82CP-809101 hydrochloride
CAS:<p>CP-809101 hydrochloride is a potent and selective 5-HT2C receptor agonist (pEC50: 9.96/7.19/6.81 for human 5-HT2C/5-HT2B/5-HT2A receptors).</p>Formula:C15H18Cl2N4OPurity:99.5%Color and Shape:SolidMolecular weight:341.24Mifentidine
CAS:<p>Mifentidine (DA 4577) is an orally available H2 receptor antagonist for the study of gastric emptying and experimental gastric and duodenal ulcers.</p>Formula:C13H16N4Purity:98.34% - 99.73%Color and Shape:SolidMolecular weight:228.29ESI-05
CAS:<p>ESI-05 (NSC-116966) is a specific 0.4 μM IC50 EPAC2 antagonist that blocks cAMP-induced EPAC2 and Rap1 activation.</p>Formula:C16H18O2SPurity:97.22%Color and Shape:SolidMolecular weight:274.38Bambuterol hydrochloride
CAS:<p>Bambuterol hydrochloride (KWD-2183 hydrochloride) , a long-acting beta-adrenoceptor agonist, is utilized for the treating of asthma.</p>Formula:C18H30ClN3O5Purity:99.53% - 99.61%Color and Shape:White SolidMolecular weight:403.91Senktide acetate
<p>Senktide acetate is a tachykinin NK3 receptor agonist that promotes the consolidation or expression of ELM and can be used to study Alzheimer's disease.</p>Formula:C42H59N7O13SPurity:98.26%Color and Shape:SolidMolecular weight:902.02Aripiprazole
CAS:Aripiprazole (OPC-14597) is a piperazine/quinolone antipsychotic, partial agonist at 5-HT1A/D2, and antagonist at 5-HT2A.Formula:C23H27Cl2N3O2Purity:99.43% - 99.62%Color and Shape:Colourless Flake Crystalline SolidMolecular weight:448.39YNT-185
CAS:<p>YNT-185 is a nonpeptide, selective agonist of the orexin type-2 receptor (OX2R), demonstrating EC50 values of 0.028 μM and 2.75 μM for OX2R and OX1R,</p>Formula:C33H37N5O5SPurity:99.67%Color and Shape:SolidMolecular weight:615.74Alverine citrate
CAS:<p>Alverine citrate (NSC 35459) is utilized in functional gastrointestinal disorders.</p>Formula:C26H35NO7Purity:98.53% - 99.43%Color and Shape:CoaMolecular weight:473.57KGA-2727
CAS:<p>KGA-2727: potent, selective SGLT1 inhibitor (human Ki 97.4 nM, rat 43.5 nM), with high selectivity over SGLT2 for diabetes treatment.</p>Formula:C26H40N4O8Purity:98.46%Color and Shape:SolidMolecular weight:536.62(3aR,9aR)-Fluparoxan
CAS:<p>(3aR,9aR)-Fluparoxan is a highly selective and potent adrenergic receptor α2B antagonist for the prevention, amelioration or treatment of neurodevelopmental</p>Formula:C10H10FNO2Purity:97.82%Color and Shape:SoildMolecular weight:195.19BIBO3304 TFA
CAS:<p>BIBO3304 TFA: Oral, selective NPY Y1 receptor blocker; IC50: 0.38 nM (human), 0.72 nM (rat).</p>Formula:C31H36F3N7O5Purity:99.5%Color and Shape:SolidMolecular weight:643.66Zolmitriptan
CAS:<p>Zolmitriptan targets 5-HT 1B/1D receptors, constricts cranial vessels, inhibits pain signals, and stops pro-inflammatory neuropeptides, alleviating migraines.</p>Formula:C16H21N3O2Purity:99.69% - 99.91%Color and Shape:White Or Kind Of White PowderMolecular weight:287.36GR 103691
CAS:<p>GR 103691 is a potent, selective dopamine D3 receptor antagonist (Ki: 0.4 nM).</p>Formula:C30H35N3O3Purity:98.94% - 99.29%Color and Shape:SolidMolecular weight:485.62AH 6809
CAS:<p>AH 6809 blocks EP1, EP2, EP3, DP receptors (Ki: 1217-1597 nM human, 350 nM mouse EP2).</p>Formula:C17H14O5Purity:97.59%Color and Shape:SolidMolecular weight:298.29Phenothiazine
CAS:<p>Phenothiazine (ENT 38) is a class of agents exhibiting antiemetic, antipsychotic, antihistaminic, and anticholinergic activities.</p>Formula:C12H9NSPurity:99.95%Color and Shape:Yellow Solid PelletsMolecular weight:199.27Noradrenaline bitartrate
CAS:<p>Norepinephrine bitartrate acts directly on the α- and β-adrenergic receptors.</p>Formula:C12H19NO10Purity:99.53% - >99.99%Color and Shape:SolidMolecular weight:337.28Fexofenadine hydrochloride
CAS:Fexofenadine Hydrochloride is a carboxylated metabolic derivative of terfenadine and long-lasting selective histamine H1 receptor antagonist, withFormula:C32H40ClNO4Purity:>99.99%Color and Shape:White Crystalline PowderMolecular weight:538.12Fosopamine(HCl)
CAS:<p>Fosopamine(HCl) is a DRDs agonist that can be used to study hypertension.</p>Formula:C9H15ClNO5PPurity:99.84%Color and Shape:SolidMolecular weight:283.65Dexpramipexole dihydrochloride
CAS:<p>Dexpramipexole dihydrochloride (KNS-760704 dihydrochloride) ((R)-Pramipexole dihydrochloride) is a neuroprotective agent and is a weak non-ergoline dopamine</p>Formula:C10H19Cl2N3SPurity:99.75% - 99.88%Color and Shape:SolidMolecular weight:284.25Ornidazole
CAS:<p>Ornidazole (Tiberal) is a nitroimidazole antiprotozoal agent used in ameba and trichomonas infections.</p>Formula:C7H10ClN3O3Purity:99.47%Color and Shape:Crystalline SolidMolecular weight:219.63MP-A08
CAS:<p>MP-A08 selectively inhibits SPHK1; targets SphK1 & SphK2 with Ki of 6.9 μM & 27 μM, respectively.</p>Formula:C27H25N3O4S2Purity:97.44%Color and Shape:SolidMolecular weight:519.64(R)-Elagolix
CAS:<p>(R)-Elagolix (NBI-56418) is an orally active, highly selective, short-term potent antagonist of the non-peptide gonadotropin-releasing hormone receptor.</p>Formula:C32H30F5N3O5Purity:99.08%Color and Shape:SolidMolecular weight:631.59Rimonabant hydrochloride
CAS:<p>Rimonabant hydrochloride (SR 141716A) 是中心大麻素受体 1 的高效选择性反向激动剂， Ki 值为1.8 nM。它也能够抑制分枝杆菌膜蛋白3。</p>Formula:C22H22Cl4N4OPurity:98.24% - 99.5%Color and Shape:Off-White To White Crystalline PowderMolecular weight:500.25Prostaglandin E1
CAS:<p>Alprostadil (PGE1) is a natural vasodilator that also inhibits platelets and induces bronchodilation, used in erectile dysfunction treatment.</p>Formula:C20H34O5Purity:99.78% - >99.99%Color and Shape:SolidMolecular weight:354.48Prochlorperazine Maleate
CAS:Prochlorperazine Maleate (Capazine) is a phenothiazine antipsychotic used principally in the treatment of NAUSEA; VOMITING; and VERTIGO.Formula:C28H32ClN3O8SPurity:99.78%Color and Shape:Off-White PowderMolecular weight:606.09Filorexant
CAS:<p>Filorexant (MK-6096) is an orally bioavailable effective and selective reversible antagonist of OX1 and OX2 receptor with (Ki <3 nM).</p>Formula:C24H25FN4O2Purity:98.88%Color and Shape:SolidMolecular weight:420.48Indusatumab
CAS:<p>Indusatumab (5F9 Monoclonal antibody) is an anti-human GUCY2C (Guanylate cyclase 2C) monoclonal antibody that can be used to synthesize antibody-drug conjugate.</p>Purity:> 95% - > 95%Color and Shape:LiquidMolecular weight:145.18 kDaBenserazide hydrochloride
CAS:<p>Benserazide hydrochloride (Ro 4-4602) is a peripherally-acting L-amino acid decarboxylase (AAAD) or DOPA decarboxylase inhibitor.</p>Formula:C10H15N3O5·HClPurity:98.63% - 99.74%Color and Shape:White Crystalline SolidMolecular weight:293.7Citalopram hydrobromide
CAS:<p>Citalopram hydrobromide (XU-62-320) , a selective serotonin reuptake inhibitor (SSRI), selectively inhibits the CNS neuronal reuptake of serotonin, thereby</p>Formula:C20H22BrFN2OPurity:99.81%Color and Shape:White Crystalline PowderMolecular weight:405.304Moxisylyte hydrochloride
CAS:Moxisylyte hydrochloride (Thymoxamine hydrochloride) is an alpha-adrenergic blocking agent that is used in Raynaud's disease.Formula:C16H26ClNO3Purity:99.94% - ≥95%Color and Shape:SolidMolecular weight:315.84Ziprasidone hydrochloride
CAS:<p>Ziprasidone hydrochloride (CP-88059 hydrochloride) is a united 5-HT (serotonin) and dopamine receptor antagonist which shows potent effects of antipsychotic</p>Formula:C21H22CL2N4OSPurity:97.97% - 99.82%Color and Shape:SolidMolecular weight:449.4EMPA
CAS:<p>EMPA is a selective, high-affinity and reversible antagonist of orexin OX2 receptor(human and rat OX2-HEK293 membranes with KD values of 1.1 and 1.4 nM</p>Formula:C23H26N4O4SPurity:99.11%Color and Shape:SolidMolecular weight:454.54Dopexamine hydrochloride
CAS:<p>Dopexamine hydrochloride (FPL60278AR) is a β2-adrenoceptor agonist that modulates inflammation and protects organs without affecting hemodynamics.</p>Formula:C22H34Cl2N2O2Purity:98.55%Color and Shape:SolidMolecular weight:429.42Cisapride
CAS:Cisapride (R 51619), a 5-HT4 agonist, enhances gut peristalsis and gastric emptying, reduces reflux.Formula:C23H29ClFN3O4Purity:99.77%Color and Shape:White To Slightly Biege Powder SolidMolecular weight:465.95Protriptyline hydrochloride
CAS:<p>Protriptyline HCl: a tricyclic antidepressant that increases norepinephrine and serotonin levels and has anticholinergic effects.</p>Formula:C19H21N·HClPurity:98.54% - 99.98%Color and Shape:SolidMolecular weight:299.84Aniracetam
CAS:<p>Aniracetam (Ro 13-5057)(Ro 13-5057), a nootropic and neuroprotective drug, selectively modulates the AMPA receptor and nAChR.</p>Formula:C12H13NO3Purity:99.88% - 99.89%Color and Shape:White Crystalline Or Crystalline PowdeMolecular weight:219.24Promazine hydrochloride
CAS:Promazine hydrochloride, a phenothiazine less potent than chlorpromazine, treats disturbed behavior and nausea.Formula:C17H21ClN2SPurity:99.90%Color and Shape:SolidMolecular weight:320.88Terlipressin Acetate
CAS:<p>Terlipressin Acetate, a highly selective vasopressin V1 receptor agonist, on OGD/R-induced damage in intestinal epithelial cells (IEC-6).</p>Formula:C56H82N16O19S2Purity:98.50% - 99.69%Color and Shape:SolidMolecular weight:1347.5Pizotifen
CAS:<p>Pizotifen is a serotonin antagonist with mild anticholinergic effects, used in migraine prevention. Not available in the USA.</p>Formula:C19H21NSPurity:99.93%Color and Shape:SolidMolecular weight:295.44Abarelix
CAS:<p>Abarelix (PPI 149) is a potent gonadotrophin-releasing hormone (GnRH) antagonist, which is used for prostate cancer treatment.</p>Formula:C72H95ClN14O14Purity:>99.99%Color and Shape:SolidMolecular weight:1416.06Vabicaserin hydrochloride
CAS:<p>Vabicaserin hydrochloride (SCA 136) is a selective agonist of 5-hydroxytryptamine 2C (5-HT2C) receptor (EC50: 8 nM).</p>Formula:C15H21ClN2Purity:98.32%Color and Shape:SolidMolecular weight:264.79Desipramine hydrochloride
CAS:Desipramine hydrochloride (Norimipramine) ,a secondary amine tricyclic antidepressant (TCA), is the hydrochloride salt form of desipramine.Formula:C18H23ClN2Purity:99.58% - 99.94%Color and Shape:White To Off-White PowderMolecular weight:302.842Anatibant 2HCl
CAS:<p>Anatibant 2HCl is a small molecule bradykinin B2 receptor antagonist for the treatment of neurological disorders and may be used in the study of brain injury.</p>Formula:C34H36Cl2N6O5S·2ClHPurity:99.17% - 99.58%Color and Shape:SoildMolecular weight:784.58Cetirizine dihydrochloride
CAS:Cetirizine dihydrochloride is a potent non-drowsy antihistamine for allergies and asthma.Formula:C21H27Cl3N2O3Purity:99.4% - 99.97%Color and Shape:SolidMolecular weight:461.81Olinciguat
CAS:<p>Olinciguat (IW-1701) is an oral guanylate cyclase (sGC) stimulator.</p>Formula:C21H16F5N7O3Purity:99.33% - 99.71%Color and Shape:SolidMolecular weight:509.39Roxatidine Acetate hydrochloride
CAS:<p>Roxatidine Acetate hydrochloride (HOE 760) is a specific and competitive histamin H2-receptor antagonist. Roxatidine inhibits gastric acid secretion.</p>Formula:C19H29ClN2O4Purity:99.49%Color and Shape:SolidMolecular weight:384.9Fipexide
CAS:Fipexide (Attentil, Vigilor), a psychoactive drug of the piperazine chemical class, was developed in Italy in 1983.Formula:C20H21ClN2O4Purity:97.6% - 99.95%Color and Shape:SolidMolecular weight:388.84
