GPCR/G-Protein
GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.
Subcategories of "GPCR/G-Protein"
- 5-HT Receptor(1,003 products)
- Adenosine Receptor(247 products)
- Adrenergic Receptor(3,010 products)
- Bombesin Receptor(33 products)
- Bradykinin Receptor(60 products)
- CXCR(153 products)
- CaSR(33 products)
- Cannabinoid Receptor(215 products)
- Cholecystokinin(1 products)
- Dopamine Receptor(435 products)
- Endothelin Receptor(83 products)
- GNRH Receptor(82 products)
- GPCR19(33 products)
- GRK(32 products)
- GTPase(22 products)
- Glucagon Receptor(190 products)
- Hedgehog/Smoothened(48 products)
- Histamine Receptor(381 products)
- LPA Receptor(21 products)
- Melatonin Receptor(26 products)
- OX Receptor(41 products)
- Opioid Receptor(321 products)
- PAFR(13 products)
- PKA(51 products)
- S1P Receptor(18 products)
- SGLT(31 products)
- Sigma receptor(46 products)
Show 19 more subcategories
Found 5838 products of "GPCR/G-Protein"
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Talinolol
CAS:(±)-Talinolol is a selective β1 adrenoceptor antagonist well known for its cardioprotective and antihypertensive activity.Formula:C20H33N3O3Purity:98.8%Color and Shape:SolidMolecular weight:363.49Ibutamoren Mesylate
CAS:<p>Ibutamoren Mesylate (MK-0677) is a potent, non-peptide Growth hormone secretagogue receptor (GHSR) agonist.</p>Formula:C28H40N4O8S2Purity:97.98% - ≥98%Color and Shape:SolidMolecular weight:624.77SCH-23390 hydrochloride
CAS:SCH-23390 hydrochloride (R-(+)-SCH23390 hydrochloride) is an effective dopamine receptor antagonist, and for the D1(Ki=0.2 nM) and D5(Ki=0.3 nM).Formula:C17H19Cl2NOPurity:98% - 99.83%Color and Shape:SolidMolecular weight:324.24Clozapine N-Oxide
CAS:View and buy CLOZAPINE N-OXIDE from TargetMol.Clozapine N-oxide is a major metabolite of clozapine also known as DREADDs, technology to modulate synthetic receptors in vivo.Cited in 2 publications.Formula:C18H19ClN4OPurity:98.65% - 99.94%Color and Shape:SolidMolecular weight:342.82SB-334867 free base
CAS:SB-334867 free base (SB334867A free base) is a selective orexin-1 (OX1) receptor antagonist.Formula:C17H13N5O2Purity:99.67% - >99.99%Color and Shape:SolidMolecular weight:319.32OXA (17-33) acetate
OXA (17-33) acetate is a more potent agonist of orexin-1 receptor (OX1, EC50 = 8.29 nM)) over OX2 (EC50 = 187 nM).Formula:C79H125N23O22Purity:98.52%Color and Shape:SolidMolecular weight:1748.98MK-0557
CAS:MK-0557 is a selective and orally available antagonist of the neuropeptide Y5 receptor (Ki: 1.6 nM).Formula:C22H19FN4O3Purity:99.88%Color and Shape:SolidMolecular weight:406.41Bradykinin (acetate)
CAS:Bradykinin (acetate) is an active peptide that is generated by the kallikrein-kinin system.Formula:C52H77N15O13Purity:>99.99%Color and Shape:SolidMolecular weight:1120.26Cariprazine hydrochloride
CAS:Cariprazine hydrochloride (RGH188 hydrochloride) is an antipsychotic drug, is a D3 and D2 receptor partial agonist((Ki of 0.085 nM and 0.49 nM, respectively)Formula:C21H33Cl3N4OPurity:99.78% - >99.99%Color and Shape:SolidMolecular weight:463.872-Furoyl-LIGRLO-amide TFA(729589-58-6 free base)
<p>2-Furoyl-LIGRLO-amide TFA(729589-58-6 free base) is a potent and selective protease-activated receptor 2 (PAR2) agonist.</p>Formula:C38H64F3N11O10Purity:>99.99%Color and Shape:SolidMolecular weight:891.98Ditolylguanidine
CAS:Ditolylguanidine (Di-o-tolylguanidine) is an agonist of sigma receptor (σ1/σ2 receptor).Formula:C15H17N3Purity:98.42%Color and Shape:White To Pinkish Solid PowderMolecular weight:239.32Tetradecyl Phosphonate
CAS:Tetradecyl Phosphonate 是溶血磷脂酸 1 (LPA1)、LPA2 和 LPA3 受体的泛拮抗剂。Formula:C14H31O3PPurity:99.95%Color and Shape:White To Off-White PowderMolecular weight:278.37Midodrine
CAS:<p>Midodrine ((±)-Midodrin), an adrenergic alpha-1 agonist, belongs to the class of medications known as vasopressors.</p>Formula:C12H18N2O4Purity:99.89%Color and Shape:SolidMolecular weight:254.281-[(5-methylisoxazol-3-yl)methyl]piperazine
CAS:<p>1-[(5-methylisoxazol-3-yl)methyl]piperazine (Piperazine, 1-[(5-methyl-3-isoxazolyl)methyl]- (9CI)) is a P2Y12 inhibitor.</p>Formula:C9H15N3OPurity:95%Color and Shape:SolidMolecular weight:181.23VKGILS-NH2 Acetate
<p>VKGILS-NH2 Acetate is a reversed amino acid sequence control peptide for SLIGKV-NH2, a protease-activated receptor 2 (PAR2) agonist.</p>Formula:C30H58N8O9Purity:98.83%Color and Shape:SolidMolecular weight:674.83CGS 21680 Hydrochloride
CAS:CGS 21680 Hydrochloride (CGS 21680 HCl)(IC50=22 nM), an adenosine receptor agonist, exhibits 140-fold potency in A2 receptor over A1 receptor.Formula:C23H29N7O6·HClPurity:96.74% - 99.53%Color and Shape:SolidMolecular weight:535.98Hydroxyzine dihydrochloride
CAS:<p>Hydroxyzine dihydrochloride treats allergies, pruritus, anxiety; causes drowsiness; also an antiemetic and sedative.</p>Formula:C21H27ClN2O2·2HClPurity:99.46% - 99.79%Color and Shape:Oil PowderMolecular weight:447.83Dapagliflozin ((2S)-1,2-propanediol, hydrate)
CAS:<p>Dapagliflozin ((2S)-1,2-propanediol, hydrate) (BMS-512148 (2S)-1,2-propanediol, hydrate) is a selective, orally active inhibitor of the renal sodium-glucose co-</p>Formula:C24H35ClO9Purity:99.88% - 99.94%Color and Shape:SolidMolecular weight:502.98DORA-22
CAS:<p>DORA-22 is a dual orexin receptor antagonist, improves mild stress-induced insomnia with minimal effect on memory</p>Formula:C23H22F2N4O2Purity:97.67%Color and Shape:SolidMolecular weight:424.44Pridopidine
CAS:Pridopidine (FR310826), a low-affinity D2R antagonist, enhances motor skills and has neuroprotective effects in Huntington's R6/2 mice.Formula:C15H23NO2SPurity:95.2% - 99.89%Color and Shape:SolidMolecular weight:281.41AZ3451
CAS:<p>AZ3451 is an allosteric antagonist of protease-activated receptor-2 (PAR2, IC50: 23 nM).</p>Formula:C30H27BrN4O3Purity:98.12%Color and Shape:SolidMolecular weight:571.46lumateperone Tosylate
CAS:lumateperone Tosylate (ITI-007) is a 5-HT2A receptor antagonist, a partial agonist of presynaptic D2 receptors and an antagonist of postsynaptic D2 receptors.Formula:C31H36FN3O4SPurity:95.83% - 99.95%Color and Shape:SolidMolecular weight:565.7Peptide YY (PYY) (3-36), human
CAS:Peptide YY (PYY) (3-36), human (Peptide YY (3-36)) is a gut hormone peptide. Peptide YY (PYY) (3-36), human acts as a Y2 receptor agonist to reduce appetite.Formula:C176H272N52O54Purity:97.76%Color and Shape:SolidMolecular weight:3980.42Doxazosin
CAS:<p>Doxazosin (UK 33274) is a long-lasting inhibitor of α1-adrenoceptors that is widely used to treat benign prostatic hyperplasia and lower urinary tract symptoms.</p>Formula:C23H25N5O5Purity:99.47% - 99.87%Color and Shape:SolidMolecular weight:451.48Brimonidine
CAS:<p>Brimonidine (Bromoxidine) is a drug used as eye drops under the brand names Alphagan and Alphagan-P.</p>Formula:C11H10BrN5Purity:99.626%Color and Shape:Yellow SolidMolecular weight:292.13Tianeptine sodium salt
CAS:<p>Tianeptine sodium salt 是一种选择性5-HT 摄取促进剂，具有抗抑郁、抗焦虑和神经保护作用，可用于缓解疼痛的研究。</p>Formula:C21H24ClN2NaO4SPurity:99.82%Color and Shape:SolidMolecular weight:458.93ZM241385
CAS:<p>ZM-241385 is a high-affinity antagonist ligand selective for the adenosine A2A receptor.</p>Formula:C16H15N7O2Purity:97.02% - 99.69%Color and Shape:SolidMolecular weight:337.34Ropinirole hydrochloride
CAS:Ropinirole HCl (SKF-101468A) is a selective D2 dopamine agonist (Ki: 29 nM) with antiparkinsonian effects.Formula:C16H24N2O·HClPurity:99.87% - 99.98%Color and Shape:Off-White SolidMolecular weight:296.84D3-βArr
CAS:D3-βArr (NCGC00379308) is a positive allosteric modulator for thyrotropin receptor (TSHR), which initiates translocation of β-Arr 1 (EC50: 11.6 μM) by directFormula:C20H23N5Purity:98.82%Color and Shape:SolidMolecular weight:333.43Vilazodone Hydrochloride
CAS:<p>Vilazodone Hydrochloride (EMD 68843) , a partial agonist of 5-HT1A receptors and specific serotonin reuptake inhibitor (SSRI), is utilized in treating of the</p>Formula:C26H27N5O2·HClPurity:99.56% - >99.99%Color and Shape:SolidMolecular weight:477.99PF-06291874
CAS:<p>PF-06291874 (Glucagon receptor antagonists-4) (Glucagon receptor antagonists-4) is a highly effective and orally active antagonist of the glucagon receptor.</p>Formula:C26H28F3N3O4Purity:99.12% - 99.27%Color and Shape:SolidMolecular weight:503.51S 38093 HCl
CAS:S 38093 is a novel brain-penetrant antagonist/inverse agonist of H3 receptors.Formula:C17H25ClN2O2Purity:97.91%Color and Shape:SolidMolecular weight:324.85Cetirizine Impurity B dihydrochloride
CAS:Cetirizine Impurity B dihydrochloride is a Cetirizine antihistamine byproduct with anti-allergic properties.Formula:C19H23Cl3N2O2Purity:97.33%Color and Shape:SolidMolecular weight:417.76Reboxetine mesylate
CAS:<p>Reboxetine mesylate (FCE20124 mesylate) is a norepinephrine reuptake inhibitor (Ki: 8.2 nM).</p>Formula:C19H23NO3·CH4O3SPurity:99.18% - 99.87%Color and Shape:Tan Or Off-White Cyrstalline SolidMolecular weight:409.5Anisotropine Methylbromide
CAS:Anisotropine Methylbromide is an anticholinergic agent and has been used for relief of gastrointestinal spasm and for the suppression of gastric acid secretion.Formula:C17H32BrNO2Purity:99.73%Color and Shape:Crystals From Acetone SolidMolecular weight:362.35ABT-702 dihydrochloride
CAS:ABT-702 dihydrochloride is a potent adenosine kinase (AK) inhibitor.Formula:C22H21BrCl2N6OPurity:98.42% - 98.98%Color and Shape:SolidMolecular weight:536.25A-381393
CAS:A-381393 is a selective and brain penetrate dopamine D4 receptor antagonist (Kis: 1.9/1.5/1.6 nM for human dopamine D4.2/D4.4/D4.7 receptor).Formula:C20H24N4Purity:99.00%Color and Shape:SolidMolecular weight:320.43Parmodulin 2
CAS:<p>ML161 (Parmodulin 2) inhibits PAR1, blocking platelet activation and thrombin-induced activity (IC50: 0.26μM).</p>Formula:C17H17BrN2O2Purity:97.35% - 99.95%Color and Shape:SolidMolecular weight:361.23Derenofylline
CAS:<p>Derenofylline is a selective and potent adenosine A(1) antagonist in vitro (Ki=1 nM)</p>Formula:C18H20N4OPurity:98.09%Color and Shape:SolidMolecular weight:308.38NNC-0640
CAS:<p>NNC-0640 is a negative allosteric modulator of Human Glucagon Receptor with an IC50 of 69.2 nM.</p>Formula:C29H31N7O4SPurity:97.04%Color and Shape:SolidMolecular weight:573.67Diquafosol tetrasodium
CAS:<p>Diquafosol Tetrasodium is a P2Y2 receptor agonist that stimulates the secretion of mucins from ocular tissues Diquafosol tetrasodium (INS365) improves tear film</p>Formula:C18H22N4Na4O23P4Purity:98.25% - 99.97%Color and Shape:SolidMolecular weight:878.23Org 27569
CAS:<p>Org 27569, an allosteric modulator of cannabinoid CB1 receptor, can induce a CB1 receptor state that is characterized by decreased inverse agonist affinity and</p>Formula:C24H28ClN3OPurity:>99.99% - ≥95%Color and Shape:SolidMolecular weight:409.95Antalarmin
CAS:Antalarmin is a CRHR1 antagonist that blocks adrenocorticotropin-releasing hormone-induced hypertension, blocks CRF activation.Formula:C24H34N4Purity:99.99%Color and Shape:SolidMolecular weight:378.55Xaliproden hydrochloride
CAS:<p>Xaliproden is a compound that mimics the effects of nerve growth factor and is also a serotonin 5-HT1A receptor agonist.</p>Formula:C24H23ClF3NPurity:99.99%Color and Shape:SolidMolecular weight:417.89CAY10526
CAS:CAY10526 (BTH) is a selective mPGES-1 inhibitor that acts as an inhibitor of the NF-κB signaling pathway.Formula:C12H7BrO3SPurity:98.75%Color and Shape:SolidMolecular weight:311.15Velneperit
CAS:<p>Velneperit (S2367) is potent and selective neuropeptide Y (NPY) Y5 receptor under evaluating for treatment of obesity.</p>Formula:C17H24F3N3O3SPurity:99.70%Color and Shape:SolidMolecular weight:407.45Cerlapirdine
CAS:<p>Cerlapirdine (PF-05212365), a 5-HT6 receptor antagonist, is in trials for Alzheimer's and schizophrenia cognition issues.</p>Formula:C22H23N3O3SPurity:98.77%Color and Shape:SolidMolecular weight:409.5SCH442416
CAS:<p>SCH442416: selective A2A adenosine receptor antagonist; Ki: 0.048 nM (human), 0.5 nM (rat).</p>Formula:C20H19N7O2Purity:99.58%Color and Shape:SolidMolecular weight:389.41Elinzanetant
CAS:<p>Elinzanetant is a dual antagonist of neurokinin (NK) receptors 1 and 3 and modulates reproductive hormone secretion.</p>Formula:C33H35F7N4O3Purity:98% - 99.13%Color and Shape:SolidMolecular weight:668.64Hemokinin 1 (human) acetate(491851-53-7 free base)
<p>Hemokinin 1 acetate: Human SP homolog, NK1 agonist (IC50: NK1 1.8 nM), proliferates B-cells, antihypertensive.</p>Formula:C56H88N14O16SPurity:97.82%Color and Shape:SolidMolecular weight:1245.45
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