GPCR/G-Protein
GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.
Subcategories of "GPCR/G-Protein"
- 5-HT Receptor(1,025 products)
- Adenosine Receptor(248 products)
- Adrenergic Receptor(3,031 products)
- Bombesin Receptor(35 products)
- Bradykinin Receptor(61 products)
- CXCR(154 products)
- CaSR(34 products)
- Cannabinoid Receptor(216 products)
- Cholecystokinin(1 products)
- Dopamine Receptor(445 products)
- Endothelin Receptor(86 products)
- GNRH Receptor(84 products)
- GPCR19(33 products)
- GRK(33 products)
- GTPase(22 products)
- Glucagon Receptor(191 products)
- Hedgehog/Smoothened(49 products)
- Histamine Receptor(385 products)
- LPA Receptor(21 products)
- Melatonin Receptor(26 products)
- OX Receptor(41 products)
- Opioid Receptor(325 products)
- PAFR(14 products)
- PKA(59 products)
- S1P Receptor(17 products)
- SGLT(31 products)
- Sigma receptor(46 products)
Show 19 more subcategories
Found 5963 products of "GPCR/G-Protein"
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D3-βArr
CAS:D3-βArr (NCGC00379308) is a positive allosteric modulator for thyrotropin receptor (TSHR), which initiates translocation of β-Arr 1 (EC50: 11.6 μM) by directFormula:C20H23N5Purity:98.82%Color and Shape:SolidMolecular weight:333.43Vilazodone Hydrochloride
CAS:Vilazodone Hydrochloride (EMD 68843) , a partial agonist of 5-HT1A receptors and specific serotonin reuptake inhibitor (SSRI), is utilized in treating of theFormula:C26H27N5O2·HClPurity:99.56% - >99.99%Color and Shape:SolidMolecular weight:477.99PF-06291874
CAS:PF-06291874 (Glucagon receptor antagonists-4) (Glucagon receptor antagonists-4) is a highly effective and orally active antagonist of the glucagon receptor.Formula:C26H28F3N3O4Purity:99.12% - 99.27%Color and Shape:SolidMolecular weight:503.51S 38093 HCl
CAS:S 38093 is a novel brain-penetrant antagonist/inverse agonist of H3 receptors.Formula:C17H25ClN2O2Purity:97.91%Color and Shape:SolidMolecular weight:324.85Ref: TM-T4087
1mg37.00€5mg71.00€10mg92.00€25mg164.00€50mg225.00€100mg323.00€200mg437.00€1mL*10mM (DMSO)71.00€Cetirizine Impurity B dihydrochloride
CAS:Cetirizine Impurity B dihydrochloride is a Cetirizine antihistamine byproduct with anti-allergic properties.Formula:C19H23Cl3N2O2Purity:97.33%Color and Shape:SolidMolecular weight:417.76Reboxetine mesylate
CAS:Reboxetine mesylate (FCE20124 mesylate) is a norepinephrine reuptake inhibitor (Ki: 8.2 nM).Formula:C19H23NO3·CH4O3SPurity:99.18% - 99.87%Color and Shape:Tan Or Off-White Cyrstalline SolidMolecular weight:409.5Ref: TM-T6963
5mg42.00€10mg71.00€25mg157.00€50mg290.00€100mg462.00€500mg1,008.00€1mL*10mM (DMSO)48.00€Anisotropine Methylbromide
CAS:Anisotropine Methylbromide is an anticholinergic agent and has been used for relief of gastrointestinal spasm and for the suppression of gastric acid secretion.Formula:C17H32BrNO2Purity:99.73%Color and Shape:Crystals From Acetone SolidMolecular weight:362.35ABT-702 dihydrochloride
CAS:ABT-702 dihydrochloride is a potent adenosine kinase (AK) inhibitor.Formula:C22H21BrCl2N6OPurity:98.42% - 98.98%Color and Shape:SolidMolecular weight:536.25Ref: TM-T4668
1mg62.00€2mg87.00€5mg119.00€10mg187.00€25mg350.00€50mg530.00€100mg748.00€500mg1,578.00€1mL*10mM (DMSO)140.00€A-381393
CAS:A-381393 is a selective and brain penetrate dopamine D4 receptor antagonist (Kis: 1.9/1.5/1.6 nM for human dopamine D4.2/D4.4/D4.7 receptor).Formula:C20H24N4Purity:99.00%Color and Shape:SolidMolecular weight:320.43Ref: TM-T5397
1mg38.00€5mg75.00€10mg111.00€25mg198.00€50mg288.00€100mg414.00€200mg583.00€1mL*10mM (DMSO)84.00€Parmodulin 2
CAS:ML161 (Parmodulin 2) inhibits PAR1, blocking platelet activation and thrombin-induced activity (IC50: 0.26μM).Formula:C17H17BrN2O2Purity:97.35% - 99.95%Color and Shape:SolidMolecular weight:361.23Derenofylline
CAS:Derenofylline is a selective and potent adenosine A(1) antagonist in vitro (Ki=1 nM)Formula:C18H20N4OPurity:98.09%Color and Shape:SolidMolecular weight:308.38NNC-0640
CAS:NNC-0640 is a negative allosteric modulator of Human Glucagon Receptor with an IC50 of 69.2 nM.Formula:C29H31N7O4SPurity:97.04%Color and Shape:SolidMolecular weight:573.67Ref: TM-T7364
1mg48.00€2mg65.00€5mg96.00€10mg169.00€25mg298.00€50mg454.00€100mg655.00€1mL*10mM (DMSO)96.00€Diquafosol tetrasodium
CAS:Diquafosol Tetrasodium is a P2Y2 receptor agonist that stimulates the secretion of mucins from ocular tissues Diquafosol tetrasodium (INS365) improves tear filmFormula:C18H22N4Na4O23P4Purity:98.25% - 99.97%Color and Shape:SolidMolecular weight:878.23Org 27569
CAS:Org 27569, an allosteric modulator of cannabinoid CB1 receptor, can induce a CB1 receptor state that is characterized by decreased inverse agonist affinity andFormula:C24H28ClN3OPurity:>99.99% - ≥95%Color and Shape:SolidMolecular weight:409.95Antalarmin
CAS:Antalarmin is a CRHR1 antagonist that blocks adrenocorticotropin-releasing hormone-induced hypertension, blocks CRF activation.Formula:C24H34N4Purity:99.99%Color and Shape:SolidMolecular weight:378.55Ref: TM-T70433
1mg81.00€5mg170.00€10mg241.00€25mg408.00€50mg552.00€100mg745.00€1mL*10mM (DMSO)173.00€Xaliproden hydrochloride
CAS:Xaliproden is a compound that mimics the effects of nerve growth factor and is also a serotonin 5-HT1A receptor agonist.Formula:C24H23ClF3NPurity:99.99%Color and Shape:SolidMolecular weight:417.89Ref: TM-T9272
1mg38.00€5mg80.00€10mg114.00€25mg222.00€50mg356.00€100mg512.00€200mg735.00€1mL*10mM (DMSO)92.00€CAY10526
CAS:CAY10526 (BTH) is a selective mPGES-1 inhibitor that acts as an inhibitor of the NF-κB signaling pathway.Formula:C12H7BrO3SPurity:98.75%Color and Shape:SolidMolecular weight:311.15Velneperit
CAS:Velneperit (S2367) is potent and selective neuropeptide Y (NPY) Y5 receptor under evaluating for treatment of obesity.Formula:C17H24F3N3O3SPurity:99.70%Color and Shape:SolidMolecular weight:407.45Ref: TM-T17222
1mg37.00€2mg52.00€5mg79.00€10mg119.00€25mg259.00€50mg439.00€100mg647.00€1mL*10mM (DMSO)87.00€Cerlapirdine
CAS:Cerlapirdine (PF-05212365), a 5-HT6 receptor antagonist, is in trials for Alzheimer's and schizophrenia cognition issues.Formula:C22H23N3O3SPurity:98.77%Color and Shape:SolidMolecular weight:409.5Ref: TM-T30798
1mg81.00€5mg170.00€10mg274.00€25mg543.00€50mg780.00€100mg1,074.00€1mL*10mM (DMSO)198.00€SCH442416
CAS:SCH442416: selective A2A adenosine receptor antagonist; Ki: 0.048 nM (human), 0.5 nM (rat).Formula:C20H19N7O2Purity:99.58%Color and Shape:SolidMolecular weight:389.41Ref: TM-T23336
1mg46.00€5mg88.00€10mg132.00€25mg266.00€50mg409.00€100mg573.00€200mg807.00€1mL*10mM (DMSO)92.00€Elinzanetant
CAS:Elinzanetant is a dual antagonist of neurokinin (NK) receptors 1 and 3 and modulates reproductive hormone secretion.
Formula:C33H35F7N4O3Purity:98% - 99.13%Color and Shape:SolidMolecular weight:668.64Hemokinin 1 (human) acetate(491851-53-7 free base)
Hemokinin 1 acetate: Human SP homolog, NK1 agonist (IC50: NK1 1.8 nM), proliferates B-cells, antihypertensive.Formula:C56H88N14O16SPurity:97.82%Color and Shape:SolidMolecular weight:1245.45Lerisetron
CAS:Lerisetron is an antagonist of serotonin type 3 (5-HT3) receptor, with antiemetic activity.Formula:C18H20N4Purity:99.15% - 99.82%Color and Shape:SolidMolecular weight:292.38M871 acetate
M871 acetate is a selective galanin GAL2 receptor antagonist (Ki values are 13.1 and 420 nM at GAL2 and GAL1 receptors, respectively).It blocks pronociceptiveFormula:C110H167N27O30Purity:99.84%Color and Shape:SolidMolecular weight:2347.67Eltoprazine hydrochloride
CAS:Eltoprazine hydrochloride (DU 28853 hydrochloride) is a partial agonist at serotonin 5-HT1A, 5-HT1B, and 5-HT2B receptors (Ki value of 40, 52, and 81 nM,Formula:C12H17ClN2O2Purity:99.35%Color and Shape:SolidMolecular weight:256.73Guanfacine hydrochloride
CAS:Guanfacine hydrochloride (Intuniv) is a centrally acting antihypertensive agent with specificity towards ADRENERGIC ALPHA-2 RECEPTORS.Formula:C9H10Cl3N3OPurity:99.89% - 99.91%Color and Shape:SolidMolecular weight:282.55Plecanatide
CAS:Plecanatide acetate is an analogue of Uroguanylin. It is an orally active guanylate cyclase-C (GC-C) receptor agonist.Formula:C65H104N18O26S4Purity:97.51%Color and Shape:SolidMolecular weight:1681.89Metoclopramide hydrochloride hydrate
CAS:Metoclopramide hydrochloride hydrate (Metoclopramide monohydrochloride monohydrate) is a dopamine D2 antagonist that is a drug used for digestive dysfunction.Formula:C14H25Cl2N3O3Purity:99.33%Color and Shape:SolidMolecular weight:354.27Galanin Receptor Ligand M35 TFA
Galanin Receptor Ligand M35 TFA is a high-affinity ligand and antagonist of galanin receptor (Kd=0.1 nM).Formula:C109H154N27F3O28Purity:99.45%Color and Shape:SolidMolecular weight:2347.62TY-52156
CAS:TY-52156 is an effective and selective S1P3 receptor antagonist (Ki: 110 nM).Formula:C18H19Cl2N3OPurity:99.91% - 99.91%Color and Shape:SolidMolecular weight:364.27Ref: TM-T17183
2mg40.00€5mg60.00€10mg87.00€25mg166.00€50mg298.00€100mg510.00€200mg683.00€1mL*10mM (DMSO)66.00€BD-1047 dihydrobromide
CAS:BD-1047 dihydrobromide (BD1047.2HBr) , a selective functional antagonist of sigma receptors, has antipsychotic activity in animal models predictive of efficacyFormula:C13H22Br2Cl2N2Purity:98.13% - 99.39%Color and Shape:SolidMolecular weight:437.04Ref: TM-T1740
1mg37.00€2mg48.00€5mg73.00€10mg95.00€25mg168.00€50mg290.00€100mg490.00€1mL*10mM (DMSO)74.00€Amperozide
CAS:Amperozide (FG 5606), an atypical antipsychotic, antagonizes 5-HT2A and modulates dopamine activity for schizophrenia treatment.Formula:C23H29F2N3OPurity:99.68%Color and Shape:SolidMolecular weight:401.49Ref: TM-T23733
1mg87.00€5mg178.00€10mg295.00€25mg497.00€50mg708.00€100mg964.00€500mg1,918.00€1mL*10mM (DMSO)321.00€Nemifitide acetate(173240-15-8 free base)
Nemifitide acetate, synthetic 5-amino acid antidepressant, has quick effect, mimics MIF.Formula:C35H47FN10O8Purity:97.97%Color and Shape:SolidMolecular weight:754.85Carazolol
CAS:Carazolol (Suacron) is a high-affinity antagonist/partial inverse agonist (also referred to as a beta blocker) of the β-adrenergic receptor.Formula:C18H22N2O2Purity:99% - 99.53%Color and Shape:Yellowish SolidMolecular weight:298.38HT-2157
CAS:HT-2157 (SNAP-37889) is a selective, high-affinity competitive antagonist of the galanin-3 receptor (Gal3), demonstrating effective inhibition of this target.Formula:C21H13F3N2OPurity:98.33%Color and Shape:SolidMolecular weight:366.34L-732138
CAS:L-732138 is a potent and competitive antagonist of neurokinin-1 (NK-1) receptor(IC50 : 2.3 nM)Formula:C22H18F6N2O3Purity:99.77%Color and Shape:SolidMolecular weight:472.38Ref: TM-T8235
5mg50.00€10mg80.00€25mg135.00€50mg192.00€100mg286.00€200mg416.00€1mL*10mM (DMSO)To inquireIndophagolin
CAS:Indophagolin: autophagy inhibitor, IC50 140 nM; blocks P2X4, P2X1, P2X3 receptors, IC50s 2.71, 2.40, 3.49 μM.Formula:C19H15BrClF3N2O3SPurity:99.76%Color and Shape:SolidMolecular weight:523.75Ref: TM-T8946
1mg42.00€5mg82.00€10mg116.00€25mg188.00€50mg260.00€100mg366.00€200mg497.00€1mL*10mM (DMSO)95.00€Phenelzine
CAS:Phenelzine is a MAOI antidepressant, boosting brain catecholamines, effective for endogenous depression.Formula:C8H12N2Purity:98%Color and Shape:LiquidMolecular weight:136.19Ref: TM-T9540
5mgTo inquire10mgTo inquire25mgTo inquire50mgTo inquire100mgTo inquire200mgTo inquire500mgTo inquireBay 55-9837 acetate
Bay 55-9837 acetate is a potent and highly selective VPAC2 agonist(Kd = 0.65 nM) and can be used in type 2 diabetes studies.Purity:98.27%Color and Shape:LiquidMolecular weight:N/APancreatic Polypeptide, rat acetate
Pancreatic Polypeptide, rat acetate is an agonist of NPY receptor, with high affinity at NPYR4.Purity:97.53%Color and Shape:SolidMolecular weight:N/ARef: TM-TP1044L
1mg215.00€5mg510.00€10mg692.00€25mg1,009.00€50mg1,378.00€100mg1,863.00€200mg2,520.00€Neuropeptide Y (29-64), amide, human acetate
Neuropeptide Y (29-64), amide, human acetate is involved in Alzheimer's disease (AD) and protects rat cortical neurons against β-Amyloid toxicity.Purity:98.42%Color and Shape:LiquidMolecular weight:N/APancreatic Polypeptide (human) acetate
Pancreatic Polypeptide (human) acetate is a C-terminally amidated 36 amino acid peptide, which acts as a neuropeptide Y (NPY) Y4/Y5 receptor agonist.Purity:97.26%Color and Shape:LiquidMolecular weight:N/AUrotensin I acetate (83930-33-0 Free base)
Urotensin I acetate, CRF1/CRF2 agonist: pEC50s - hCRF1 11.46, hCRF2 9.36, rCRF2α 9.85; KIs - hCRF1 0.4 nM, rCRF2α 1.8 nM, mCRF2β 5.7 nM.Purity:95.44% - 99.73%Color and Shape:SolidMolecular weight:N/APACAP 1-38 acetate
PACAP 1-38 acetate, a PACAP analog, targets PACAP type I (IC50=4nM) and VIP2 receptors (IC50=1nM), not VIP1.Purity:98.16%Color and Shape:LiquidMolecular weight:N/AML382
CAS:ML382 is a potent and selective MrgX1 positive allosteric modulator(EC50 : 190 nM).Formula:C18H20N2O4SPurity:99.79%Color and Shape:SolidMolecular weight:360.43Atipamezole
CAS:Atipamezole (Antisedan) is a synthetic α2 adrenergic receptor antagonist. It has also been researched in humans as a potential anti-Parkinsonian drug.Formula:C14H16N2Purity:99.88%Color and Shape:Off-White To Light Yellow Crystal PowderMolecular weight:212.29Rizatriptan
CAS:Rizatriptan (Risatriptan) is a selective 5-hydroxytryptamine 1B/1D receptor agonist used in the study of migraine.Formula:C15H19N5Purity:99.74%Color and Shape:SolidMolecular weight:269.35Fenoprofen
CAS:Fenoprofen (LILLY-5385) is a non-steroidal anti-inflammatory compound and a modifier enhancer of the melanocortin receptor, increasing ERK1/2 activation.Formula:C15H14O3Purity:98.4%Color and Shape:SolidMolecular weight:242.27Latrepirdine dihydrochloride
CAS:Latrepirdine dihydrochloride (Dimebolin dihydrochloride) is an orally active, and neuroactive antagonist of multiple drug targets.Formula:C21H25N3·2HClPurity:98.45%Color and Shape:SolidMolecular weight:392.37S-Methoprene
CAS:S-Methoprene (ZR2458), a juvenile hormone analog, acts as an insecticide influencing redox activity and male sex differentiation.
Formula:C19H34O3Purity:97.05% - 98.55%Color and Shape:SolidMolecular weight:310.47
