GPCR/G-Protein
GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.
Subcategories of "GPCR/G-Protein"
- 5-HT Receptor(985 products)
- Adenosine Receptor(244 products)
- Adrenergic Receptor(2,991 products)
- Bombesin Receptor(32 products)
- Bradykinin Receptor(59 products)
- CXCR(153 products)
- CaSR(33 products)
- Cannabinoid Receptor(209 products)
- Dopamine Receptor(433 products)
- Endothelin Receptor(79 products)
- GNRH Receptor(77 products)
- GPCR19(32 products)
- GRK(33 products)
- GTPase(22 products)
- Glucagon Receptor(181 products)
- Hedgehog/Smoothened(46 products)
- Histamine Receptor(380 products)
- LPA Receptor(21 products)
- Melatonin Receptor(26 products)
- OX Receptor(41 products)
- Opioid Receptor(309 products)
- PAFR(12 products)
- PKA(51 products)
- S1P Receptor(18 products)
- SGLT(31 products)
- Sigma receptor(46 products)
Show 18 more subcategories
Found 5696 products of "GPCR/G-Protein"
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Clopidogrel
CAS:Clopidogrel (SR-25990C), a P2Y12 receptor antagonist, decreases platelet aggregation.Formula:C16H16ClNO2SPurity:98.23% - 98.83%Color and Shape:White PowderMolecular weight:321.82ALLO-2
CAS:ALLO-2 is a Inhibitor of Drug-Resistant Smo Mutant.It inhibits Smo agonist Hh-Ag1.5-induced luciferase expression in TM3-Gli-Luc cells with IC50 of 6 nM.Formula:C18H12F3N5OPurity:99.19%Color and Shape:SolidMolecular weight:371.32Buflomedil hydrochloride
CAS:<p>Buflomedil hydrochloride (Fonzylane), a vasodilator, is used in therapy of claudication or the symptoms of the peripheral arterial disease.</p>Formula:C17H26ClNO4Purity:99.7% - 99.91%Color and Shape:White Or Off-White Crystalline PowderMolecular weight:343.85ML-109
CAS:<p>ML-109 is a potent agonist of thyroid stimulating hormone receptor (TSHR) (EC50 of 40 nM)</p>Formula:C31H29N3O5Purity:98.63%Color and Shape:SolidMolecular weight:523.58Ketotifen fumarate
CAS:<p>Ketotifen fumarate (HC 20511 fumarate) is a cycloheptathiophene blocker of histamine H1 receptors and release of inflammatory mediators.</p>Formula:C23H23NO5SPurity:99.25% - 99.73%Color and Shape:SolidMolecular weight:425.50(±) Clopidogrel hydrogen sulfate
CAS:<p>(±) Clopidogrel hydrogen sulfate (Iscover) , an antiplatelet agent pharmacologically and structurally analogous to ticlopidine, is used to inhibit blood clots</p>Formula:C16H16ClNO2S·H2SO4Purity:98.67% - 99.04%Color and Shape:Colorless To Light Yellow LiquidMolecular weight:419.9Retatrutide sodium salt
Retatrutide sodium salt is a glucagon receptor and glucagon-like peptide-1 receptor agonist for the study of type 2 diabetes mellitus.Purity:99.97%Color and Shape:SoildMK-0812 Succinate
CAS:<p>MK-0812 Succinate is an effective and selective CCR2 antagonist.</p>Formula:C28H40F3N3O7Purity:98.62% - 99.93%Color and Shape:SolidMolecular weight:587.63Hydroxyzine Pamoate
CAS:<p>Hydroxyzine Pamoate (Bobsule) is a histamine H1 receptor antagonist that is effective in the treatment of chronic urticaria and histamine-mediated pruritus.</p>Formula:C44H43ClN2O8Purity:99.49%Color and Shape:SolidMolecular weight:763.27Seltorexant
CAS:Seltorexant (JNJ-42847922) crosses the blood-brain barrier and quickly occupies OX2R binding sites in the rat brain.Formula:C21H22FN7OPurity:99.79% - >99.99%Color and Shape:SolidMolecular weight:407.44Romergoline 2HCl
Romergoline 2HCl is a D1 agonist and D2 antagonist used in the study of Parkinson's disease.Formula:C20H24Cl2N4O2Purity:99.01% - 99.40%Color and Shape:SoildMolecular weight:423.34GANT 58
CAS:<p>GANT 58 (NSC-75503) is a potent antagonist of Gli. Which inhibits GLI1-induced transcription (IC50: 5 μM).</p>Formula:C24H16N4SPurity:99.53%Color and Shape:SolidMolecular weight:392.48Nepafenac
CAS:<p>Nepafenac (AHR 9434) is an NSAID that acts as a cyclooxygenase inhibitor.</p>Formula:C15H14N2O2Purity:98.94% - 99.43%Color and Shape:SolidMolecular weight:254.28Carvedilol EP IMpurity E
CAS:<p>Carvedilol EP IMpurity E (Carvedilol USP E) is used as a pharmaceutical intermediate.</p>Formula:C9H14ClNO2Purity:99.53%Color and Shape:White To Almost White Solid CrystallineMolecular weight:203.666SEP-363856 hydrochloride
CAS:<p>SEP-363856 hydrochloride is an oral, CNS-active psychotropic for schizophrenia with a non-D2/5-HT2A mechanism.</p>Formula:C9H14ClNOSPurity:99.86% - 99.99%Color and Shape:SolidMolecular weight:219.73CI 169369
CAS:<p>CI 169369 is a selective 5-HT2 receptor antagonist used in the study of anxiety and depression.</p>Formula:C19H21ClN2SPurity:98.97%Color and Shape:SoildMolecular weight:344.9Luzindole
CAS:Luzindole (N-0774) is a selective melatonin receptor antagonist.Formula:C19H20N2OPurity:98.53%Color and Shape:Off-White Amorphous SolidMolecular weight:292.37CCX140
CAS:<p>CCX140 (CCX140-B) (CCX140-B) is an antagonist of CCR2.</p>Formula:C20H13ClF3N5O3SPurity:99.66% - 99.95%Color and Shape:SolidMolecular weight:495.86CCR2-RA-[R]
CAS:<p>CCR2-RA-[R] is a C-C chemokine receptor type 2 (CCR2) allosteric antagonist (IC50: 103 nM).</p>Formula:C18H19ClFNO3Purity:99.7%Color and Shape:SolidMolecular weight:351.8Amp579 TFA
<p>Amp579 TFA is a novel adenosine A1/A2a receptor agonist that induces acute and delayed preconditioning against myocardial shock in vivo.</p>Formula:C24H29ClF3N5O5SPurity:96.56%Color and Shape:SoildMolecular weight:592.03Frovatriptan succinate hydrate
CAS:<p>Frovatriptan treats all migraine types, nausea, vomiting, light/sound sensitivity, and prevents menstrual migraines; it targets 5-HT1B/D and 5-HT7 receptors.</p>Formula:C18H25N3O6Purity:99.66%Color and Shape:SolidMolecular weight:379.41Glycerol phenylbutyrate
CAS:Glycerol phenylbutyrate (HPN-100) (GPB) is a new generation ammonia scavenger drug and it also is a sigma-2 (σ2) receptor ligand (pKi: 8.02).Formula:C33H38O6Purity:98.54% - 99.74%Color and Shape:SolidMolecular weight:530.65BMY 25368 HCl
CAS:BMY 25368 HCl is a competitive histamine H2 receptor antagonist that antagonizes gastric secretion stimulated by pentagastrin, ethacrynic choline, and food.Formula:C19H26ClN3O3Purity:98.73% - 99.81%Color and Shape:SoildMolecular weight:379.88Promethazine
CAS:<p>Promethazine (Proazamine) is an analogue of anti-glaucoma prostaglandin (PG) .</p>Formula:C17H20N2SPurity:99.76%Color and Shape:CrystalsMolecular weight:284.42Chlorpheniramine maleate
CAS:<p>Chlorpheniramine maleate (NCI-C55265) is a histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma.</p>Formula:C20H23ClN2O4Purity:99.64% - 99.98%Color and Shape:Odorless White Crystalline Solid Or White Powder With A Bitter TasteMolecular weight:390.87Sumatriptan succinate
CAS:<p>Sumatriptan succinate (GR 43175), a serotonin1 (5-HT1) receptor agonist, is used in the acute treatment of a migraine headache.</p>Formula:C18H27N3O6SPurity:97.53% - 99.51%Color and Shape:White PowderMolecular weight:413.49L-741626
CAS:<p>L-741626 (3-(4-(4-Chlorophenyl-4-hydroxypiperidino)methyl)indole) is a selective antagonist of D2 dopamine receptor (Ki: 2.4, 100, and 220 nM for human D2, D3</p>Formula:C20H21ClN2OPurity:98.57%Color and Shape:SolidMolecular weight:340.85(-)-GSK598809 hydrochloride
CAS:<p>(-)-GSK598809 hydrochloride, a DRD3 selective antagonist, may correct reward deficits in substance dependence.</p>Formula:C22H24ClF4N5OSPurity:98.36%Color and Shape:SoildMolecular weight:517.97MK-0249 FA
MK-0249 FA is an H3 inverse agonist that can be used to study attention-deficit, hyperactivity disorder and cognitive disorders in adults.Formula:C24H26F3N3O4Purity:99.98%Color and Shape:SolidMolecular weight:477.48ONC206
CAS:<p>ONC206, an analogue of the TRAIL inducer ONC201, acts as a selective antagonist of the D2-like dopamine receptors (DRD2/3/4) at nanomolar concentrations and</p>Formula:C23H22F2N4OPurity:99.38% - 99.81%Color and Shape:SolidMolecular weight:408.44Dazmegrel HCl
Dazmegrel HCl is a platelet thromboxane inhibitor used in the study of myocardial infarction and arrhythmias.Formula:C16H18ClN3O2Purity:98.30%Color and Shape:SolidMolecular weight:319.79Clomipramine hydrochloride
CAS:<p>Clomipramine HCl (Anafranil) is a serotonin-inhibiting tricyclic antidepressant, well-absorbed and metabolized to desmethylclomipramine in the liver.</p>Formula:C19H23ClN2·HClPurity:99.04% - 99.47%Color and Shape:White To Slightly Yellow Crystalline PowderMolecular weight:351.31Midodrine hydrochloride
CAS:<p>Midodrine, metabolized to desglymidodrine, activates alpha-1 receptors, raising blood pressure without CNS effects. It's a prodrug in hydrochloride form.</p>Formula:C12H19ClN2O4Purity:99.79% - >99.99%Color and Shape:Crystalline SolidMolecular weight:290.74(S)-(-)-Atenolol
CAS:(S)-(-)-Atenolol has beta-adrenergic blocking effects.Formula:C14H22N2O3Purity:99.31% - 99.81%Color and Shape:SolidMolecular weight:266.34Apelin-13
CAS:Apelin-13 is a 13-amino acid peptide sequence found in the central and peripheral nervous system that is an endogenous ligand for the G protein-coupled receptorFormula:C69H111N23O16SPurity:96.81%Color and Shape:SolidMolecular weight:1550.83J-113863
CAS:J-113863 is also a potent antagonist of the human CCR3 (IC50 of 0.58 nM) , but a weak antagonist of the mouse CCR3 (IC50 of 460 nM).Formula:C30H37Cl2IN2O2Purity:95.11%Color and Shape:SolidMolecular weight:655.44Tetrahydrozoline
CAS:<p>Tetrahydrozoline (Tetryzoline) is an alpha-adrenergic agonist that causes vasoconstriction and is widely used in the study of nasal and conjunctival congestion.</p>Formula:C13H16N2Purity:97.85% - 99.77%Color and Shape:SolidMolecular weight:200.28RS102895 hydrochloride
CAS:RS102895 hydrochloride is a potent antagonist of CCR2(IC50 of 360 nM).Formula:C21H22ClF3N2O2Purity:98.95%Color and Shape:SolidMolecular weight:426.86Clopidogrel hydrogen sulfate
CAS:<p>Clopidogrel hydrogen sulfate is a selective P2Y12 receptor blocker that inhibits platelet adhesion and aggregation.</p>Formula:C16H16ClNO2S·H2SO4Purity:99.57% - 99.79%Color and Shape:SolidMolecular weight:419.9Tolnaftate
CAS:<p>Tolnaftate (NP-27) is a synthetic antifungal agent.</p>Formula:C19H17NOSPurity:98.85%Color and Shape:White PowderMolecular weight:307.41Terbutaline Sulfate
CAS:Terbutaline Sulfate (Terbutaline hemisulfate) is a selective beta-2 adrenergic agonist used as a bronchodilator and tocolytic.Formula:C12H19NO3H2SO4Purity:99.47% - 99.94%Color and Shape:Crystalline PowderMolecular weight:274.32Pheniramine maleate
CAS:Pheniramine maleate (Trimetose), an alkylamine derivative with antihistaminic and vasodilatory properties, binds to histamine H1 receptors.Formula:C16H20N2·C4H4O4Purity:99.85%Color and Shape:Physical Description White Powder With A Faint Amine-Like Odor Melting Point 107°CMolecular weight:356.426-Iodopravadoline
CAS:<p>6-Iodopravadoline (AM630) is an antagonist of CB2 (Ki: 31.2 nM). And it shows 165-fold selectivity more than CB1 receptors.</p>Formula:C23H25IN2O3Purity:99.29%Color and Shape:Off-White SolidMolecular weight:504.36Tolnapersine TFA
<p>Tolnapersine TFA is a mixed dopamine agonist and alpha adrenergic receptor antagonist.</p>Formula:C23H27F3N2O3Purity:99.14%Color and Shape:SoildMolecular weight:436.47Quipazine dimaleate
CAS:<p>Quipazine dimaleate is a selective 5-HT3 agonist.</p>Formula:C21H23N3O8Purity:>99.99%Color and Shape:SolidMolecular weight:445.42Crotedumab
CAS:<p>Crotedumab (REGN1193) is a humanized antibody targeting GCGR, which reduces fasting blood glucose and improves glucose tolerance, used in diabetes research.</p>Purity:>95%Color and Shape:LiquidFamotidine
CAS:Famotidine, a histamine H2-blocker, curbs gastric acid production, lowering volume and acidity.Formula:C8H15N7O2S3Purity:98.93% - 99.91%Color and Shape:White To Off-White Crystalline PowderMolecular weight:337.45Itopride hydrochloride
CAS:Itopride hydrochloride (Ganaton) is an AChE and D2DR inhibitor.Formula:C20H27ClN2O4Purity:99.59%Color and Shape:White Or Pale Brownish CrystalMolecular weight:394.9Isoprenaline hydrochloride
CAS:Isoprenaline hydrochloride (NCI-c55630) is a potent beta-adrenergic agonist with the peripheral vasodilator, bronchodilator, and cardiac stimulating properties.Formula:C11H18ClNO3Purity:98% - 99.65%Color and Shape:Turn Brownish-Pink Upon Prolonged Exposure To Air (Ntp 1992)Molecular weight:247.719Sarizotan 2HCl
CAS:<p>Sarizotan 2HCl is an hERG channel inhibitor and 5-hydroxytryptamine 5-HT1A receptor agonist with potential antidepressant effects for the study of Parkinsonian movement disorders.</p>Formula:C22H23Cl2FN2OPurity:98.83%Color and Shape:SoildMolecular weight:421.34
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