DNA/RNA Synthesis
Inhibitors of DNA and RNA synthesis are compounds that interfere with the replication and transcription processes in cells, thereby preventing the production of essential genetic material. These inhibitors can target various enzymes and proteins involved in nucleic acid synthesis, making them valuable tools for studying the mechanisms of replication, transcription, and translation. They are also used in developing treatments for infections and cancer. At CymitQuimica, we offer a broad spectrum of DNA/RNA synthesis inhibitors to support your research in molecular biology, virology, and therapeutic development.
Found 706 products of "DNA/RNA Synthesis"
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Nedaplatin
CAS:<p>Nedaplatin, a cisplatin derivative, induces tumor DNA damage (IC50: 94 μM) through platinum-DNA cross-links, causing apoptosis.</p>Formula:C2H8N2O3PtPurity:99.88% - >99.99%Color and Shape:Straw Yellow PowderMolecular weight:303.17DNA2 inhibitor C5
CAS:<p>DNA2 inhibitor C5 is a specific cancer sensitizer with an IC50 of 20 μM, targeting multiple DNA2 activities.</p>Formula:C10H6N2O5Purity:99.05%Color and Shape:SolidMolecular weight:234.16Capecitabine
CAS:<p>Capecitabine is a prodrug in the antimetabolite class, transformed into cytotoxic 5-FU by tumor cells, inhibiting DNA and RNA synthesis.</p>Formula:C15H22FN3O6Purity:99.81% - >99.99%Color and Shape:Less Solid Colourless SolidMolecular weight:359.35BMVC-8C3O
CAS:<p>BMVC-8C3O is a DNA G-quadruplex (G4) ligand.Cost-effective and quality-assured.</p>Formula:C42H53I3N4O3Purity:99.72%Color and Shape:SolidMolecular weight:1042.61Xanthopterin (hydrate)
CAS:<p>Xanthopterin Hydrate is isolated from butterfly wings and could replace folic acid in the nutrition of many animal species.</p>Formula:C6H7N5O3Purity:98.99% - 99.93%Color and Shape:Yellow To Orange Crystalline PowderMolecular weight:197.15Hycanthone
CAS:<p>Hycanthone (Etrenol(mesylate)) is a potent drug of antischistosomal.</p>Formula:C20H24N2O2SPurity:98.78%Color and Shape:Yellow-Orange Powder (Ntp 1992)Molecular weight:356.48Floxuridine
CAS:<p>Floxuridine (FUDR) is an antimetabolite, floxuridine inhibits thymidylate synthase, resulting in disruption of DNA synthesis and cytotoxicity.</p>Formula:C9H11FN2O5Purity:98.92% - 99.96%Color and Shape:SolidMolecular weight:246.19Vitamin D2
CAS:<p>Ergocaliferol (Vitamin D2), derived from ergosterol by UV, inhibits bladder tumor promotion and leukemia, and blocks DNA Polymerase.</p>Formula:C28H44OPurity:98.73% - 99.89%Color and Shape:Prisms From Acetone 1998)Molecular weight:396.65Farudodstat
CAS:<p>Farudodstat (ASLAN003) is an orally active and potent inhibitor of DHODH with antitumor activity. It has the potential to be a first-in-class candidate in AML.</p>Formula:C19H14F2N2O3Purity:98.36%Color and Shape:SolidMolecular weight:356.32Dithranol
CAS:<p>Dithranol (cignoline) is an anthracene derivative that disrupts MITOCHONDRIA function and structure and is used for the treatment of DERMATOSES, especially</p>Formula:C14H10O3Purity:93.49% - 99.33%Color and Shape:Physical Description Lemon Yellow Leaflets Or Plates Or An Orange Powder MeltingMolecular weight:226.23MALAT1-IN-1
CAS:<p>MALAT1-IN-1 is an effective dose-dependent Malat1 inhibitor, not altering Neat1 expression.</p>Formula:C19H21N3O2Purity:99.58%Color and Shape:SolidMolecular weight:323.39Fludarabine
CAS:<p>Fludarabine (Fludarabinum) is a fluorinated purine analog, an inhibitor of nucleic acid synthesis and an inhibitor of STAT1 activation.</p>Formula:C10H12FN5O4Purity:99.65% - 99.89%Color and Shape:White SolidMolecular weight:285.23Enrofloxacin
CAS:<p>Enrofloxacin (BAY-Vp2674) is a veterinary antibacterial agent, used in poultry.</p>Formula:C19H22FN3O3Purity:99.43% - >99.99%Color and Shape:Pale Yellow CrystalsMolecular weight:359.39DI-87
CAS:<p>DI-87 (TRE-515) is a novel and orally available dCK (deoxycytidine kinase) inhibitor. DI-87 binds to dCK reduces the production of dNTP inhibits tumor growth.</p>Formula:C23H30N6O3S2Purity:99.76%Color and Shape:SolidMolecular weight:502.65Enoxacin
CAS:<p>Enoxacin (NSC-629661) is a broad-spectrum 6-fluoronaphthyridinone antibacterial agent (fluoroquinolones) structurally related to nalidixic acid.</p>Formula:C15H17FN4O3Purity:98.68% - 99.89%Color and Shape:Off-White To Yellow CrystalsMolecular weight:320.32Metarrestin
CAS:<p>Metarrestin (ML246) is a first-in-class perinucleolar compartment inhibitor with a favorable PK profile, which effectively suppresses metastasis.</p>Formula:C31H30N4OPurity:99.45%Color and Shape:SolidMolecular weight:474.6NMDI14
CAS:<p>NMDI14 is an inhibitor of nonsense mediated RNA decay (NMD).</p>Formula:C21H25N3O4SPurity:97.79% - 99.37%Color and Shape:SolidMolecular weight:415.51Procaine hydrochloride
CAS:<p>Procaine HCl is a benzoic acid derivative used as a local anesthetic, blocking nerve impulses and sensation.</p>Formula:C13H20N2O2·HClPurity:99.1% - 99.22%Color and Shape:White Crystalline PowderMolecular weight:272.77Oxaliplatin
CAS:<p>Oxaliplatin (L-OHP) is a DNA alkylating agent, an inhibitor of DNA synthesis.</p>Formula:C8H14N2O4PtPurity:97% - 99.93%Color and Shape:SolidMolecular weight:397.29DHODH-IN-11
CAS:<p>DHODH-IN-11 is a leflunomide derivative and weak dihydroorotate dehydrogenase (DHODH) inhibitor with a pKa of 5.03.</p>Formula:C15H11N3O2Purity:98.14%Color and Shape:SolidMolecular weight:265.27Rifapentine
CAS:<p>Rifapentine (Rifapentinum) is a long-acting, cyclopentyl-substituted derivative of rifamycin used to treat mycobacterium infections.</p>Formula:C47H64N4O12Purity:95.74% - ≥98%Color and Shape:SolidMolecular weight:877.03PTC299
CAS:<p>PTC299 ((4-chlorophenyl) (1S)-6-chloro-1-(4-methoxyphenyl)-1,3,4,9-tetrahydropyrido[3,4-b]indole-2-carboxylate) is an orally active inhibitor of VEGFA mRNA</p>Formula:C25H20Cl2N2O3Purity:99.72%Color and Shape:SolidMolecular weight:467.34Carboplatin
CAS:<p>Carboplatin (JM-8) is a cisplatin derivative, a DNA synthesis inhibitor.</p>Formula:C6H12N2O4PtPurity:98% - 99.72%Color and Shape:White Crystalline PowderMolecular weight:371.25Rifaximin
CAS:<p>Rifaximin: an oral semi-synthetic antibiotic from rifamycin SV; targets bacterial RNA polymerase to halt growth.</p>Formula:C43H51N3O11Purity:99.18% - 99.40%Color and Shape:Red-Orange Crystalline PowderMolecular weight:785.88Cytarabine
CAS:<p>Cytarabine (Ara-C) is a nucleoside analog, an inhibitor of DNA synthesis (IC50=16 nM).</p>Formula:C9H13N3O5Purity:99.83% - 99.93%Color and Shape:Fine Off-White Crystalline PowderMolecular weight:243.22Novobiocin Sodium
CAS:<p>Novobiocin Sodium (Albamycinsodium) binds to DNA gyrase and blocks adenosine triphosphatase (ATPase) activity. Novobiocin sodium is an antibiotic compound.</p>Formula:C31H35N2NaO11Purity:99% - 99.28%Color and Shape:SolidMolecular weight:634.61Gemcitabine
CAS:<p>Gemcitabine (LY188011) is a synthetic cytosine nucleoside derivative and an inhibitor of DNA synthesis.</p>Formula:C9H11F2N3O4Purity:98.66% - 99.67%Color and Shape:SolidMolecular weight:263.25-Fluorouridine
CAS:<p>5-fluorouridine is also known as FUrd, 5-Fluorouracil 1-beta-D-ribofuranoside, 5-Fur, or 5-Fluoro-uridine.</p>Formula:C9H11FN2O6Purity:99.76% - 99.85%Color and Shape:White PowderMolecular weight:262.19Phleomycin
CAS:<p>Phleomycin is one of the anticancer glycopeptide antibiotics which cause DNA cleavage.</p>Formula:C48H69N17O20S2Purity:98%Color and Shape:SolidMolecular weight:1268.29Levofloxacin hydrate
CAS:<p>Levofloxacin hydrate (Cravit hydrate) is a third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity.</p>Formula:C18H20FN3O4H2OPurity:98.26%Color and Shape:Pale Yellow SolidMolecular weight:370.38TK216
CAS:<p>TK216 is a potent inhibitor of E26 transformation-specific (ETS) with anticancer activity.</p>Formula:C19H15Cl2NO3Purity:97.22%Color and Shape:SolidMolecular weight:376.23ART558
CAS:<p>ART558 is a potent, selective, low molecular weight, allosteric DNA polymerase activity of Polθ inhibitor (IC50=7.9 nM).</p>Formula:C21H21F3N4O2Purity:99.18% - 99.67%Color and Shape:SolidMolecular weight:418.41Carmofur
CAS:<p>Carmofur (HCFU) is a highly potent acid ceramidase inhibitor, used in the treatment of breast and colorectal cancer.</p>Formula:C11H16FN3O3Purity:98.53% - 99.98%Color and Shape:SolidMolecular weight:257.26Folic acid
CAS:<p>Folic acid (Vitamin B9) is a vitamin B9 that is essential for the synthesis of DNA/RNA and for the production new cells. Cost-effective and quality-assured.</p>Formula:C19H19N7O6Purity:99.19% - 99.27%Color and Shape:Yellowish-Orange Crystals; Extremely Thin Platelets (Elongated @ 2 Ends) From Hot Water 482°FMolecular weight:441.40Foscarnet sodium
CAS:<p>Foscarnet sodium (Phosphonoformate) is an antiviral agent used in the treatment of cytomegalovirus retinitis.</p>Formula:CNa3O5PPurity:98.52%Color and Shape:White Or Almost White Crystalline PowderMolecular weight:191.95N-Dodecyl-β-D-maltoside
CAS:<p>N-Dodecyl-β-D-maltoside (Lauryl Maltoside) has also been employed in applications such as in the purification and stabilization of RNA polymerase and the</p>Formula:C24H46O11Purity:99.7% - >99.99%Color and Shape:White PowderMolecular weight:510.62Enoxacin hydrate
CAS:<p>Enoxacin hydrate (AT-2266 hydrate) is a broad-spectrum 6-fluoronaphthyridinone antibacterial agent.</p>Formula:C15H17FN4O3H2OPurity:99.50%Color and Shape:SolidMolecular weight:347.34RG7800
CAS:<p>RG7800 (RO6885247) has the potential for spinal muscular atrophy treatment. RG7800 is an SMN2 splicing modifier.</p>Formula:C24H28N6OPurity:99.44%Color and Shape:SolidMolecular weight:416.52Hydroxyurea
CAS:<p>Hydroxyurea (Hydroxycarbamide), an antineoplastic agent, inhibits DNA synthesis through the inhibition of ribonucleoside diphosphate reductase.</p>Formula:CH4N2O2Purity:99.85% - 99.92%Color and Shape:SolidMolecular weight:76.05JH-RE-06
CAS:<p>JH-RE-06 disrupts mutagenic translesion synthesis (TLS) by preventing the recruitment of mutagenic POLζ.</p>Formula:C20H16Cl3N3O4Purity:99.29%Color and Shape:SolidMolecular weight:468.72BAY-2402234
CAS:<p>BAY-2402234: a selective DHODH inhibitor targeting myeloid cancers with low-nanomolar potency.</p>Formula:C21H18ClF5N4O4Purity:98.9%Color and Shape:SolidMolecular weight:520.84Adenine
CAS:<p>Adenine: a purine nucleobase vital for ATP, NAD, FAD production, and DNA/RNA synthesis.</p>Formula:C5H5N5Purity:99.39% - 99.95%Color and Shape:SolidMolecular weight:135.13Doxifluridine
CAS:<p>Doxifluridine (AMC 0101) is a fluoropyrimidine derivative and oral prodrug of the antineoplastic agent 5-fluorouracil (5-FU) with antitumor activity.</p>Formula:C9H11FN2O5Purity:99.47% - 99.86%Color and Shape:White SolidMolecular weight:246.19Cinoxacin
CAS:<p>Cinoxacin (Compound 64716), an older synthetic antimicrobial, was related to the quinolone class of antibiotics.</p>Formula:C12H10N2O5Purity:99.62% - 99.98%Color and Shape:SolidMolecular weight:262.22Methotrexate
CAS:<p>Methotrexate (WR19039) is a folate analog, an inhibitor of the dihydrofolate reductase DHFR.</p>Formula:C20H22N8O5Purity:96.84% - 99.91%Color and Shape:Orange-Brown Crystalline Powder Chemotherapy Drug That Interferes With Dna And Rna SynthesisMolecular weight:454.44PZL-A
CAS:<p>PZL-A, PZL-A, an activator of mtDNA synthesis, restored the activity of POLγ mutant variant.</p>Formula:C19H17ClN4O2Purity:99.88%Color and Shape:SoildMolecular weight:368.82Famciclovir
CAS:<p>Famciclovir (BRL 42810) inhibits Herpes virus DNA polymerase by mimicking nucleosides.</p>Formula:C14H19N5O4Purity:99.85%Color and Shape:Off-White PowderMolecular weight:321.33Procaine
CAS:<p>Procaine (Vitamin H3) is a slow-acting ester local anesthetic with a short effect, used for infiltration, nerve, and spinal blocks.</p>Formula:C13H20N2O2Purity:99.57% - 99.73%Color and Shape:Anhydrous Plates Tables From Ligroin Or Ether SolidMolecular weight:236.31Oxolinic acid
CAS:<p>Oxolinic acid (Nidantin) is a synthetic antimicrobial related to NALIDIXIC ACID and used in URINARY TRACT INFECTIONS.</p>Formula:C13H11NO5Purity:98.39% - 99.72%Color and Shape:Crystals From Dimethylformamide White Crystalline PowderMolecular weight:261.23Daunorubicin hydrochloride
CAS:<p>Daunorubicin hydrochloride (Rubidomycin hydrochloride), an anthracycline aminoglycoside antineoplastic, inhibits DNA replication and repair and RNA and protein</p>Formula:C27H29NO10·HClPurity:96.21% - 99.53%Color and Shape:Cancer DrugMolecular weight:563.99Epirubicin hydrochloride
CAS:<p>Epirubicin hydrochloride (Pharmorubicin) is a Topo and Foxp3 inhibitor. Epirubicin hydrochloride has antitumor activity. Cost-effective and quality-assured.</p>Formula:C27H30ClNO11Purity:98.13% - 99.79%Color and Shape:Orange-Red At Neutral Phs And Violet Blue Over Ph 9 (Ntp 1992)Molecular weight:579.98EFdA-TP
CAS:<p>EFdA-TP: potent HIV-1 RT inhibitor; acts via immediate/delayed chain termination (ICT/DCT) and multiple pathways.</p>Formula:C12H15FN5O12P3Color and Shape:SolidMolecular weight:533.195DMT-dG(ib) Phosphoramidite
CAS:<p>DMT-dG(ib) Phosphoramidite can be used to synthesize DNA.</p>Formula:C44H54N7O8PPurity:99.21%Color and Shape:SolidMolecular weight:839.9223-Oxa-OSW-1
CAS:<p>23-Oxa-OSW-1 (SBF-1), a derivative of OSW-1, serves as a potent inhibitor of the osterol-binding protein (OSBP) with demonstrated antitumor activity [1] [2].</p>Formula:C54H82O16Color and Shape:SolidMolecular weight:987.22Tilatamig samrotecan
<p>Tilatamig samrotecan (AZD9592) is an antibody-drug conjugate (ADC) designed to deliver a topoisomerase I inhibitor (TOP1i). It targets epidermal growth factor receptor (EGFR) and c-MET and demonstrates antitumor activity. The compound induces DNA double-strand breaks, elevates pRAD50 and γH2AX expression, and inhibits the growth of non-small cell lung cancer.</p>Color and Shape:Odour SolidLIN28-IN-2
<p>LIN28-IN-2 (Compound Ln268) blocks the interaction between the zinc finger domain (ZKD) of Lin28 and RNA substrates, inhibiting both Lin28a and Lin28b. It also suppresses the proliferation of Lin28-positive cancer cells and the growth of 3D spheroids.</p>Formula:C9H7FN2O2SColor and Shape:SolidMolecular weight:226.227RNase L ligand 1
<p>RNase L ligand 1 (Compound F1-COOH) serves as a ligand for RNase L and is utilized in the synthesis of F1-RIBOTAC.</p>Formula:C21H21Cl2NO3Color and Shape:SolidMolecular weight:406.302DIZ-3
CAS:<p>DIZ-3: Selective G4 ligand, stabilizes structure, inhibits ALT cancer cell growth by inducing cell cycle arrest and apoptosis.</p>Formula:C46H44F2N8Color and Shape:SolidMolecular weight:746.895'-O-DMT-rI
CAS:<p>5’-O-DMT-Ri can be used in the synthesis of oligoribonucleotides[1].</p>Formula:C31H30N4O7Color and Shape:SolidMolecular weight:570.59KWR137
<p>KWR137 is a WRN degrader with an IC50 of 8 nM. It exhibits significant antiproliferative activity against MSI-H cells, with a GI50 of 509 nM for SW48 cells and 824 μM for HCT116. Additionally, KWR137 demonstrates antitumor growth effects in xenograft mouse models. This compound is applicable for cancer research.</p>Formula:C33H31ClF3N9O4Color and Shape:SolidMolecular weight:710.105Clofarabine-5'-triphosphate
CAS:<p>Clofarabine-5'-triphosphate is a metabolite of Clofarabine, produced via phosphorylation by deoxycytidine kinase (dCK). It exhibits cytotoxicity in cancer cells by inhibiting DNA synthesis and DNA repair.</p>Formula:C10H14ClFN5O12P3Color and Shape:SolidMolecular weight:543.625'-O-DMT-PAC-dA
CAS:<p>5’-O-DMT-PAC-dA can be used in the synthesis of oligoribonucleotides[1].</p>Formula:C39H37N5O7Color and Shape:SolidMolecular weight:687.74LB80317
CAS:<p>LB-80317, a DNA polymerase inhibitor, is used potentially for the potential treatment of hepatitis B virus infection.</p>Formula:C10H14N5O5PColor and Shape:SolidMolecular weight:315.22S-MGB-234
CAS:<p>S-MGB-234 treats AAT, effective against T. congolense and T. vivax, no cross-resistance or shared transport with diamidines.</p>Formula:C30H32N8O4Color and Shape:SolidMolecular weight:568.638RNA recruiter 2
<p>RNA recruiter 2 serves as a QSOX1mRNA ligand. This compound functions as a target RNA ligand (RIBOTAC's target RNA ligand) and aids in developing RIBOTAC RNA degraders with antitumor activity. Additionally, RNA recruiter 2 is utilized in the synthesis of F1-RIBOTAC.</p>Formula:C20H16FNO4SColor and Shape:SolidMolecular weight:385.409Deoxythymidine-5'-triphosphate sodium hydrate
<p>dTTP sodium hydrate, a DNA synthesis component, is a nucleoside triphosphate.</p>Formula:C10H17N2O14P3·xNa·xH2OColor and Shape:SolidMolecular weight:C10H17N2O14P3.xNa.xH2OGuanosine triphosphate
CAS:<p>Guanosine triphosphate (GTP), a native nucleotide, and its derivatives may serve as specific inhibitors against COVID-19 [1].</p>Formula:C10H16N5O14P3Color and Shape:SolidMolecular weight:523.18DNA31
CAS:<p>DNA31 is a potent RNA polymerase inhibitor.</p>Formula:C48H58N4O13Purity:98%Color and Shape:SolidMolecular weight:898.997-TFA-ap-7-Deaza-ddG
CAS:<p>Compound 19d, a nucleotide derivative, is used to make thiotriphosphate dye terminators for DNA sequencing.</p>Formula:C16H16F3N5O4Color and Shape:SolidMolecular weight:399.33Phen-DC3 Trifluoromethanesulfonate
CAS:<p>Phen-DC3 Trifluoromethanesulfonate targets G-quadruplexes and inhibits FANCJ/DinG helicases; IC50s: 65±6/50±10 nM.</p>Formula:C36H26F6N6O8S2Purity:98%Color and Shape:SolidMolecular weight:848.75m7GpppGmpG
CAS:<p>m7GpppGmpG, a trinucleotide 5′ cap analog, exhibits capping efficiencies of 86% for the RNAs obtained [1].</p>Formula:C32H43N15O25P4Color and Shape:SolidMolecular weight:1161.66Nuclease S1
CAS:<p>Nuclease S1 breaks down ssDNA and RNA, trims protruding ends of dsDNA.</p>Color and Shape:SolidUCK2 Inhibitor-3
CAS:<p>UCK2 Inhibitor-3 blocks UCK2 (IC50: 16.6μM) and DNA polymerases eta/kappa (IC50s: 56μM/16μM), aiding uridine salvage in certain cells.</p>Formula:C19H13BrFN5O2SColor and Shape:SolidMolecular weight:474.31FF-10502
CAS:<p>FF-10502, a pyrimidine analog of Gemcitabine, inhibits DNA polymerases α/β, targeting dormant cancer cells.</p>Formula:C9H12FN3O3SColor and Shape:SolidMolecular weight:261.27PRV-IN-1
<p>PRV-IN-1 (compound c14) demonstrates significant antiviral activity against pseudorabies virus (PRV) with an EC50 of 14 pM and a CC50 of 343.7 μM. It effectively inhibits the replication of PRV.</p>Formula:C20H28N4O3Color and Shape:SolidMolecular weight:372.461Agrocin 84
CAS:<p>Agrocin 84 is a microbial metabolite that inhibits DNA and protein synthesis, as well as amino acid transport, in the susceptible and virulent Agrobacterium strain H-38-9.</p>Formula:C22H36N6O16P2Color and Shape:SolidMolecular weight:702.499RAD51-IN-3
CAS:<p>RAD51-IN-3 is a Rad51 inhibitor.</p>Formula:C31H41N5O5S2Color and Shape:SolidMolecular weight:627.82Votoplam HCl
CAS:<p>Votoplam HCl is a systemically acting gene splicing regulator that down-regulates the levels of huntingtin protein, which to inhibit Huntington's disease (HD).</p>Formula:C21H26ClN9OPurity:99.02%Color and Shape:SoildMolecular weight:455.94KC12
<p>KC12 acts as an inhibitor of the FOXM1 transcription factor. In cancer cells of the MDA-MB-231 line, KC12 exhibits cytotoxicity with an IC50 of 6.13 µM.</p>Formula:C23H17F3N2O3SColor and Shape:SolidMolecular weight:458.453Anticancer agent 262
<p>Anticanceragent 262 (compound 3h) is a DNA-intercalating antineoplastic agent with an IC50 value of 5.7 µM against A549 cancer cells.</p>Formula:C26H31N3OColor and Shape:SolidMolecular weight:401.544dUTP trisodium
CAS:<p>dUTP trisodium (Deoxyuridine triphosphate) is a deoxyuridine phosphate having a triphosphate group at the 5'-position and can be used for PCR.</p>Formula:C9H12N2Na3O14P3Purity:100.00%Color and Shape:SolidMolecular weight:534.09TH1085
CAS:<p>TH1085 is an enhancer of OGG1. TH1085 stimulates DNA repair and protects cells from the environmental hazard paraquat (PQ).</p>Formula:C17H21N3Purity:99.99%Color and Shape:SolidMolecular weight:267.37m7Gpppm6AmpG
CAS:<p>m7Gpppm6AmpG, a trinucleotide mRNA 5’ cap analog, facilitates RNA synthesis in vitro [1].</p>Formula:C33H45N15O24P4Color and Shape:SolidMolecular weight:1159.69NLS (PKKKRKV)
CAS:<p>NLS (PKKKRKV) peptide from SV40 big T antigen boosts nuclear entry for gene transfer studies.</p>Formula:C40H78N14O8Purity:98%Color and Shape:SolidMolecular weight:883.14m7GpppApG
CAS:<p>M7GpppApG is a trinucleotide mRNA 5' cap analog utilized for in vitro RNA synthesis [1].</p>Formula:C31H41N15O24P4Color and Shape:SolidMolecular weight:1131.64Bisucaberin
CAS:<p>Bisucaberin: a siderophore with anticancer properties; inhibits L1210/1MC cells and enhances 1023 cell cytolysis.</p>Formula:C18H32N4O6Color and Shape:SolidMolecular weight:400.476T-2513
CAS:<p>T-2513 inhibits topoisomerase I by covalently bonding to its DNA complex, blocking DNA replication and causing cell death.</p>Formula:C25H27N3O5Color and Shape:SolidMolecular weight:449.507WRN inhibitor 17
CAS:<p>WRN inhibitor 17 (Compound 250) is an orally active inhibitor of Werner syndrome ATP-dependent helicase (WRN), specifically targeting the helicase domain activity of WRN. It holds potential for use in cancer research.</p>Formula:C33H34F4N4O6SColor and Shape:SolidMolecular weight:690.71Orotidine 5′-monophosphate trisodium
CAS:<p>Orotidine 5'-monophosphate trisodium, a pyrimidine nucleotide, is synthesized through the de novo DNA synthesis pathway by various microorganisms, including M.</p>Formula:C10H10N2Na3O11PColor and Shape:SolidMolecular weight:434.14Dezecapavir
CAS:<p>Dezecapavir (example 4) acts as an effective inhibitor of viral replication, exhibiting an EC50 value of 0.025 nM in MT2 cells with a CC50 greater than 0.5 μM.</p>Formula:C37H29ClF9N9O5SColor and Shape:SolidMolecular weight:918.19Ac-dA Phosphoramidite
CAS:<p>Ac-dA Phosphoramidite is a phosphinamide monomer utilized for oligonucleotide synthesis.</p>Formula:C42H50N7O7PColor and Shape:SolidMolecular weight:795.878SD49-7
CAS:<p>SD49-7 is an inhibitor of histone lysine demethylase 4 (KDM4) with an IC50 of 0.19 µM.</p>Formula:C18H14N2O3Purity:99.91%Color and Shape:SoildMolecular weight:306.32Emicoron
CAS:<p>Importazole is an inhibitor of the transport receptor importin-β. It specifically inhibits importin-β likely by altering its interaction with RanGTP.</p>Formula:C52H58N6O4Purity:98%Color and Shape:SolidMolecular weight:831.05VPC-18005
CAS:<p>VPC-18005: a luciferase inhibitor that blocks ERG-induced transcription by binding ERG-ETS, hindering DNA attachment.</p>Formula:C15H17N3O3SPurity:99.95%Color and Shape:SoildMolecular weight:319.385-Iminodaunorubicin
CAS:<p>5-Iminodaunorubicin: a quinone-altered anthracycline with antitumor effects, causing DNA breaks in cancer.</p>Formula:C27H30N2O9Color and Shape:SolidMolecular weight:526.545'-O-TBDMS-dU
CAS:<p>5'-O-TBDMS-dU can be used in the synthesis of oligoribonucleotides.</p>Formula:C15H26N2O5SiColor and Shape:SolidMolecular weight:342.4672'-(2-Nitrobenzyl)-ATP trisodium
<p>2'-(2-Nitrobenzyl)-ATP trisodium is an rATP analogue that acts as a transcription terminator. It inhibits T7 RNA polymerase from continuing RNA chain extension.</p>Formula:C17H18N6Na3O15P3Color and Shape:SolidMolecular weight:707.973615'-O-DMT-2'-O-TBDMS-Bz-rC
CAS:<p>5'-O-DMT-2'-O-TBDMS-Bz-rC, a modified nucleoside, is utilized in the synthesis of DNA or RNA.</p>Formula:C43H49N3O8SiColor and Shape:SolidMolecular weight:763.95Cytarabine triphosphate
CAS:<p>Ara-CTP, active Cytarabine metabolite, inhibits DNA synthesis, predicts leukemic chemosensitivity.</p>Formula:C9H16N3O14P3Color and Shape:SolidMolecular weight:483.16Thio-ITP
CAS:<p>Thio-ITP (6-Thioinosine 5'-triphosphate) inhibits RNA polymerases I & II with Ki of 40.9 & 38.0 μM.</p>Formula:C10H15N4O13P3SColor and Shape:SolidMolecular weight:524.23TAC
CAS:<p>TAC is a TERT (telomerase reverse transcriptase) activator, promotes telomere synthesis, reduces cellular senescence and inflammatory cytokines</p>Formula:C14H12ClF2NO2SPurity:99.20%Color and Shape:SolidMolecular weight:331.77Bromochloroacetonitrile
CAS:<p>Bromochloroacetonitrile, a water disinfection by-product, is mutagenic and can break DNA strands.</p>Formula:C2HBrClNColor and Shape:SolidMolecular weight:154.39Vanoxonin
CAS:<p>Vanoxonin is a new thymidylate synthetase inhibitor.</p>Formula:C18H25N3O9Purity:98%Color and Shape:SolidMolecular weight:427.41MRK-952
<p>MRK-952 is a NUDIX hydrolase inhibitor. NUDIX enzymes play a role in cellular metabolism, homeostasis, and mRNA processing.</p>Formula:C20H20ClF3N6Color and Shape:SolidMolecular weight:436.8615'-O-DMT-2'-O-TBDMS-Ac-rC
CAS:<p>5’-O-DMT-2’-O-TBDMS-Ac-rC is a modified nucleoside and can be used to synthesize DNA or RNA.</p>Formula:C38H47N3O8SiColor and Shape:SolidMolecular weight:701.892Uridine triphosphate 13C9,15N2 sodium
CAS:<p>Uridine triphosphate 13C9,15N2 sodium is an isotopically labeled.UTP is a key in RNA synthesis molecule a substrate for RNA polymerase.</p>Formula:C9H1415N2NaO15P3Color and Shape:SolidMolecular weight:517.04Ac-rC Phosphoramidite
CAS:<p>Ac-rC Phosphoramidite can modify phosphodisulfide oligonucleotides.</p>Formula:C47H64N5O9PSiPurity:98.29%Color and Shape:SolidMolecular weight:902.1Remdesivir nucleoside monophosphate
CAS:<p>Remdesivir metabolite, antiviral nucleoside analog, effective against SARS-CoV and MERS-CoV.</p>Formula:C12H14N5O7PColor and Shape:SolidMolecular weight:371.245-BrdUTP sodium salt
CAS:<p>5-BrdUTP sodium salt is a TdT substrate that can be used to label the DNA double-strand breaks.</p>Formula:C9H10BrN2Na4O14P3Purity:98%Color and Shape:SolidMolecular weight:634.97RNA splicing modulator 3
CAS:<p>RNA Splicing Modulator 3 (Compound 236) is an effective RNA splicing modulator, exhibiting an AC50 value of less than 100 nM [1].</p>Formula:C19H20N6OSColor and Shape:SolidMolecular weight:380.478-NH2-ATP
CAS:<p>8-NH2-ATP is an inactive derivative of adenosine triphosphate (ATP), synthesized from 8-NH2-Ado.</p>Formula:C10H17N6O13P3Color and Shape:SolidMolecular weight:522.203'-Deoxyuridine-5'-triphosphate trisodium
<p>3'-dUTP trisodium, a nucleotide analogue, inhibits RNA polymerases I/II and UTP integration into RNA (Ki=2.0 μM).</p>Formula:C9H12N2Na3O14P3Color and Shape:SoildMolecular weight:534.08HOE 33187-O-CONH-PEG4-phenol-thiophenone-NHPh-COOEt
CAS:<p>HOE 33187-O-CONH-PEG4-phenol-thiophenone-NHPh-COOEt inhibits pre-miR-21 RNA, potential for cancer research.</p>Formula:C57H62N8O10SColor and Shape:SolidMolecular weight:1051.212'-OMe-Ac-C Phosphoramidite
CAS:<p>2'-OMe-Ac-C Phosphoramidite, a modified phosphoramidite, is utilized in the synthesis of oligonucleotides.</p>Formula:C42H52N5O9PColor and Shape:SolidMolecular weight:801.86CW-2
<p>CW-2 is a PARP1 PROTAC degrader known for its potent antiproliferative effects against MDA-MB-231 cells (IC50 = 0.72 μM) and cisplatin-resistant cells (A549/CDDP: IC50 = 3.52 μM). It exhibits synergistic antitumor activity and enhanced membrane permeability. CW-2 exerts its antitumor effects by inducing DNA damage, disrupting DNA repair, and triggering mitochondrial-dependent apoptosis (apoptosis).</p>Formula:C43H42Cl2FN11O10PtColor and Shape:SolidMolecular weight:1156.21251Demycarosyl-3D-β-D-digitoxosylmithramycin SK
CAS:<p>Demycarosyl-3D-β-D-digitoxosylmithramycin SK, an analog of Mithramycin, exhibits potent anti-tumor activity.</p>Formula:C50H72O23Color and Shape:SolidMolecular weight:1041.09Bz-rC Phosphoramidite
CAS:<p>Bz-rC Phosphoramidite is a phosphinamide monomer utilized for oligonucleotide synthesis.</p>Formula:C52H66N5O9PSiColor and Shape:SolidMolecular weight:964.185DNA Gyrase-IN-15
<p>DNA Gyrase-IN-15 (Compound 11) is an antibacterial agent that inhibits both DHPS and DNA gyrase, with IC50 values of 1.73 and 0.07 µM, respectively. It shows antimicrobial activity against Enterococcus faecium (MIC of 15.62 µg/mL), Acinetobacter baumannii, Enterobacter (MIC of 7.81 µg/mL), Pseudomonas aeruginosa, Klebsiella pneumoniae, and Staphylococcus aureus. Additionally, DNA Gyrase-IN-15 exhibits antibiofilm activity against Enterococcus faecium.</p>Formula:C31H26N4O4S2Color and Shape:SolidMolecular weight:582.693Carbazole
CAS:<p>Carbazole belongs to the class of carbazole-based organic compounds. Carbazole can form novel DNA small groove complexes, inhibiting the synthesis of new DNA or RNA.</p>Formula:C12H9NPurity:99.82%Color and Shape:SolidMolecular weight:167.211Guanosine 5'-triphosphate trisodium salt hydrate
CAS:<p>5'-GTP trisodium salt hydrate activates G proteins and is a precursor for DNA/RNA synthesis.</p>Formula:C10H18N5NaO15P3Purity:98%Color and Shape:SolidMolecular weight:564.185Ribonuclease T1
CAS:<p>Rnase T1, an endonuclease, degrades single-stranded RNA to yield 3'-GMP oligonucleotides.</p>Color and Shape:SolidEFdA-TP tetraammonium
<p>EFdA-TP tetraammonium is a potent HIV-1 RT inhibitor and DNA synthesis blocker, acting as an ICT or DCT.</p>Formula:C12H27N9O12P3Color and Shape:SolidMolecular weight:601.31TS-002902
<p>TS-002902 is a small molecule inhibitor of TUT4/7, exhibiting antiproliferative activity. It holds potential for use in cancer research.</p>Color and Shape:Odour Solidcis-Lomibuvir
CAS:<p>cis-Lomibuvir (cis-VX-222) is a selective HCV NS5B RdRp inhibitor with a Kd of 17 nM and an EC50 of 5.2 nM, targeting thumb pocket 2.</p>Formula:C25H35NO4SColor and Shape:SolidMolecular weight:445.61RNA polymerase II-IN-2
<p>RNA Pol II-IN-2 (20iii) strongly inhibits Pol II (Ki=9.5 nM), is more toxic to CHO/HEK293 than α-amanitin.</p>Formula:C41H58N10O12SColor and Shape:SolidMolecular weight:915.027-TFA-ap-7-Deaza-ddA
CAS:<p>Compound 19c is a nucleotide derivative for DNA sequencing dye terminators.</p>Formula:C16H16F3N5O3Color and Shape:SolidMolecular weight:383.331AV-153
CAS:<p>AV-153, a 1,4-dihydropyridine, reduces DNA damage, stimulates repair, and has anti-cancer properties.</p>Formula:C14H19NNaO6Color and Shape:SolidMolecular weight:320.2975'-O-DMT-N4-Bz-2'-F-dC
CAS:<p>5’-O-DMT-N4-Bz-2’-F-dC is a nucleoside with protective and modification effects.</p>Formula:C37H34FN3O7Color and Shape:SolidMolecular weight:651.683'Ome-m7GpppAmpG
CAS:<p>3'Ome-m7GpppAmpG is a trinucleotide cap with LNA, boosting translation; useful in mRNA vaccines and gene therapy.</p>Formula:C33H45N15O24P4Color and Shape:SolidMolecular weight:1159.697-Deazaxanthine
CAS:<p>7-Deazaxanthine (7DX) is an inhibitor of thymidine phosphorylase (TPase) and reduces TPase activity in a concentration-dependent manner, with an IC50 value of 40 μM. Additionally, 7-Deazaxanthine exhibits significant anti-angiogenic properties.</p>Formula:C6H5N3O2Color and Shape:SolidMolecular weight:151.12FR901463
CAS:<p>FR 901463 is a biochemical.</p>Formula:C27H42ClNO8Color and Shape:SolidMolecular weight:544.08L82-G17
CAS:<p>L82-G17 is an uncompetitive LigI-selective inhibitor in human cells with utility as a probe of the catalytic activity and cellular functions of LigI.</p>Formula:C11H9ClN4O2Purity:99.69%Color and Shape:SolidMolecular weight:264.67DMT-5Me-dC(Bz)-CE Phosphoramidite
CAS:<p>DMT-5Me-dC(Bz)-CE Phosphoramidite aids in crafting LNAs for better fluorescent probes.</p>Formula:C47H54N5O8PColor and Shape:SolidMolecular weight:847.932'-Deoxy-2'-fluoro-l-uridine
CAS:<p>2'-Deoxy-2'-fluoro-1-uridine: an L-nucleoside, inhibits RNA viruses by blocking viral RNA polymerase.</p>Formula:C9H11FN2O5Color and Shape:SolidMolecular weight:246.19Maleuric acid
CAS:<p>Maleuric acid is an anti-mitotic agent for research and boosts growth and fertility in flora and fauna.</p>Formula:C5H6N2O4Purity:98.92%Color and Shape:SolidMolecular weight:158.11c-Fos-IN-1
<p>c-Fos-IN-1 (Compound P16) acts as a c-Jun inhibitor, effectively reducing the mRNA and protein levels of c-Fos. It also inhibits the phosphorylation activity of ERK and the transcriptional activity of AP-1. This compound demonstrates anticancer properties through the inhibition of the ERK/c-Fos/Jun pathway. c-Fos-IN-1 curbs the proliferation and migration of gastric cancer cells, with an IC50 of 2.31 μM for MGC-803 cells, causing cell cycle arrest at the G2/M phase and inducing apoptosis in cancer cells. Additionally, c-Fos-IN-1 hampers the growth of gastric cancer tumors.</p>Formula:C28H35NO3Color and Shape:SolidMolecular weight:433.582Deoxythymidine-5'-triphosphate
CAS:<p>Deoxythymidine-5'-triphosphate (dTTP) is a nucleoside triphosphate involved in DNA synthesis.</p>Formula:C10H17N2O14P3Color and Shape:SolidMolecular weight:482.1675'-O-DMT-N4-Ac-2'-F-dC
CAS:<p>5’-O-DMT-N4-Ac-2’-F-dC is a modified nucleoside and can be used to synthesize DNA or RNA.</p>Formula:C32H32FN3O7Color and Shape:SolidMolecular weight:589.61Suricapavir
CAS:<p>Suricapavir is an effective viral replication inhibitor with antiviral activity.</p>Formula:C41H29ClF9N9O4SColor and Shape:SolidMolecular weight:950.23SR15006
CAS:<p>SR15006 is Krüppel-like factor 5 (KLF5) inhibitor (IC50 = 41.6 nM).</p>Formula:C16H20ClN3O4SPurity:99.87%Color and Shape:SoildMolecular weight:385.87N6-Methyladenine
CAS:<p>N6-Methyladenine (6-(Methylamino)Purine) is a modified purine commonly found in genomes of prokaryotes, protists, and plants.</p>Formula:C6H7N5Purity:99.78%Color and Shape:SolidMolecular weight:149.15Diguanosine 5′-triphosphate
CAS:<p>Diguanosine 5′-triphosphate (Gp3G) is a kind of homodinucleotide from by GTP:GTP guanylyltransferase.</p>Formula:C20H27N10O18P3Color and Shape:SolidMolecular weight:788.4095'-O-DMT-rU
CAS:<p>5’-O-DMT-rU is a modified nucleoside and can be used to synthesize RNA.</p>Formula:C30H30N2O8Color and Shape:SolidMolecular weight:546.575'-O-TBDMS-dG
CAS:<p>5’-O-TBDMS-dG is a modified nucleoside. 5’-O-DMT-2’-O-TBDMS-rI can be used in the synthesis of deoxyribonucleic acid or nucleic acid.</p>Formula:C16H27N5O4SiColor and Shape:SolidMolecular weight:381.50(+)-Glaucarubinone
<p>(+)-Glaucarubinone is a natural product that can be used as a reference standard.</p>Formula:C25H34O10Color and Shape:SolidMolecular weight:494.537Clofarabine-5'-diphosphate trisodium
<p>Clofarabine-5'-diphosphatetrisodium (Clofarabine-DP trisodium) is the sodium salt form of Clofarabine-5'-diphosphate. As a metabolic product of Clofarabine, it results from phosphorylation by deoxycytidine kinase (dCK). Clofarabine-5'-diphosphate trisodium can undergo further phosphorylation to form Clofarabine-5'-triphosphate, demonstrating cytotoxicity in cancer cells by inhibiting DNA synthesis and repair.</p>Formula:C10H10ClFN5Na3O9P2Color and Shape:SolidMolecular weight:529.58Mulnitorsen
CAS:<p>Mulnitorsen acts as an inhibitor of antisense non-coding mitochondrial RNA (ASncmtRNA) synthesis and serves as an antitumor agent [1].</p>Formula:C172H217N74O82P17S17Color and Shape:SolidMolecular weight:5704.66Cy5-dATP
<p>Cy5-dATP is a Cy5 -labeled dATP . Cy5-dATP can be incorporated into a DNA primer [1] [2] .</p>Formula:C47H58N7O19P3S2Color and Shape:SolidMolecular weight:1182.055'-O-TBDMS-N2-ibu-dG
CAS:<p>5'-O-TBDMS-N2-ibu-dG: a nucleoside derivative with strong anti-BVDV activity, useful in lead compound synthesis.</p>Formula:C20H33N5O5SiColor and Shape:SolidMolecular weight:451.59Pyrindamycin A
CAS:<p>Pyrindamycin A is an antibiotic that inhibits DNA synthesis,and shows antitumor activities against murine leukemia.</p>Formula:C26H26ClN3O8Purity:98%Color and Shape:SolidMolecular weight:543.95YL-5092
<p>YL-5092 is an inhibitor of YT521-B homology (YTH) domain-containing protein 1 (YTHDC1). It inhibits acute myeloid leukemia cells with an IC50 of 0.28-2.87 μM. YL-5092 exhibits antitumor activity in xenograft mice models using MOLM-13 or U937 cells.</p>Formula:C22H14F3N3O2SColor and Shape:SolidMolecular weight:441.435'-O-DMT-N2-DMF-dG
CAS:<p>5'-O-DMT-2'-O-TBDMS-rI, a modified nucleoside, finds application in deoxyribonucleic acid (DNA) or nucleic acid synthesis.</p>Formula:C34H36N6O6Color and Shape:SolidMolecular weight:624.698ddGTP trisodium
<p>ddGTP trisodium, a ddNTP, inhibits or serves as a substrate for DNA polymerase α, halting DNA chain elongation.</p>Formula:C10H13N5Na3O12P3Color and Shape:SolidMolecular weight:557.13N7-Methyl-guanosine-5'-triphosphate-5'-adenosine diammonium
CAS:<p>N7-Methylguanosine-5'-triphosphate-5'-adenosine (m7GpppA) diammonium, a dinucleotide cap analog, facilitates in vitro RNA transcription [1].</p>Formula:C21H35N12O17P3Color and Shape:SolidMolecular weight:820.49(S)-DI-87
CAS:<p>(S)-DI-87 is an isomer of DI-87, a oral dCK inhibitor，reduce dNTP production and cell cycle arrest. significantly inhibits tumor growth with thymidine.</p>Formula:C23H30N6O3S2Purity:99.42%Color and Shape:SoildMolecular weight:502.65wrwycr-NH2 TFA
<p>wrwycr-NH2 (TFA) is a peptide that exhibits cytotoxic properties against various cancer cells, inducing DNA damage and cell cycle arrest without causing endoplasmic reticulum stress. It possesses antitumor activity, and its efficacy is enhanced when used in combination with DNA-damaging agents.</p>Color and Shape:Odour SolidIBU-DC Phosphoramidite
CAS:<p>IBU-DC Phosphoramidite is used for synthesis of oligonucleotides.</p>Formula:C43H54N5O8PColor and Shape:SolidMolecular weight:799.9062'-Deoxyguanosine 5'-monophosphate (sodium salt hydrate)
CAS:<p>dGMP is a substrate for DNA synthesis, phosphorylated to dGDP and dGTP, and linked to mitochondrial DNA depletion syndrome in humans.</p>Formula:C10H14N5Na2O8PColor and Shape:SolidMolecular weight:409.202TS-002266
CAS:<p>TS-0022666 is a selective TUT4/7 inhibitor, antiproliferative and anti-leukaemic in vivo and in vitro, cancers with FOCAD deficiency.</p>Formula:C31H32Cl2N6O5Purity:98.18%Color and Shape:SoildMolecular weight:639.53Vasoactive intestinal contractor
CAS:<p>Vasoactive intestinal contractor, a novel member of the endothelin family, stimulates a rapid increase in intracellular Ca2+ concentration in fura-2-overexpressed Swiss 3T3 cells [1.</p>Formula:C116H161N27O32S4Color and Shape:SolidMolecular weight:2573.94R-1479
CAS:<p>R-1479 (4'-Azidocytidine) is an RdRp inhibitor with an IC50 value of 1.28 μM for HCV RNA replication in the HCV subgenomic replicon system.</p>Formula:C9H12N6O5Purity:98.11% - 99.95%Color and Shape:SolidMolecular weight:284.2312R-LOX-IN-2
CAS:<p>12R-LOX-IN-2 is a 12R-LOX inhibitor that inhibits the hyperproliferation of psoriatic cells and can be used in the study of psoriasis and other skin diseases.</p>Formula:C19H13NOPurity:99.84%Color and Shape:SolidMolecular weight:271.31Clofarabine-5'-diphosphate
CAS:<p>Clofarabine-5'-diphosphate (Clofarabine-DP) is a metabolite resulting from the phosphorylation of Clofarabine by deoxycytidine kinase (dCK). It can undergo further phosphorylation to become Clofarabine-5'-triphosphate, exhibiting cytotoxicity in cancer cells by inhibiting DNA synthesis and repair.</p>Formula:C10H13ClFN5O9P2Color and Shape:SolidMolecular weight:463.645'-O-TBDMS-Bz-dA
CAS:<p>5’-O-TBDMS-Bz-dA is a nucleoside with protective and modification effects.</p>Formula:C23H31N5O4SiColor and Shape:SolidMolecular weight:469.617m7GpppAmpG
CAS:<p>M7GpppAmpG is a trinucleotide 5′ cap analog, exhibiting capping efficiencies of 90% for the produced RNAs [1].</p>Formula:C32H43N15O24P4Color and Shape:SolidMolecular weight:1145.66Antipain
CAS:<p>Antipain, from Actinomycetes, blocks proteases and combats MNNG-induced genetic changes.</p>Formula:C27H44N10O6Purity:98%Color and Shape:SolidMolecular weight:604.713DG1
<p>DG1 (Compound 8Nc), a Thymidylate Synthase (TS) inhibitor, impedes angiogenesis and alters metabolic reprogramming in NSCLC cells, while effectively suppressing</p>Formula:C19H17N5O5SColor and Shape:SolidMolecular weight:427.4313-TP
<p>13-TP is an inhibitor of SARS-CoV-2. It effectively suppresses in vitro RNA synthesis catalyzed by the central replication-transcription complex (C-RTC, nsp12-nsp7-nsp82) of SARS-CoV-2. 13-TP fully inhibits RdRp polymerase activity and obstructs the complete extension of some primer RNAs.</p>Formula:C12H19F2N6O12P3Color and Shape:SolidMolecular weight:570.23Brr2-IN-2
<p>Brr2-IN-2 (Compound 30) is an inhibitor of Brr2, exhibiting an IC50 of 42 nM against Brr2 ATPase.</p>Formula:C21H25FN4O2Color and Shape:SolidMolecular weight:384.45Thailanstatin C
CAS:<p>Thailanstatin C from Burkholderia thailandensis blocks pre-mRNA splicing, IC50 6.84 μM.</p>Formula:C30H46ClNO9Color and Shape:SolidMolecular weight:600.15BRP
<p>BRP, a peptide related to BRINP2, exhibits anti-obesity activity through the activation of FOS. It triggers FOS activation in the central nervous system, and its effect is independent of leptin, GLP-1 receptor, and melanocortin 4 receptor.</p>Color and Shape:Odour Solid5-Methylcytidine 5′-triphosphate
CAS:<p>5-Methylcytidine 5′-triphosphate (5-Methyl-CTP), a modified nucleoside triphosphate, enhances translational properties and stability while reducing innate</p>Formula:C10H18N3O14P3Color and Shape:SolidMolecular weight:497.18Garenoxacin
CAS:<p>Garenoxacin (BMS284756) is a novel oral des-fluoro(6) quinolone for the treatment of Gram-positive and Gram-negative bacterial infections.</p>Formula:C23H20F2N2O4Purity:98%Color and Shape:SolidMolecular weight:426.41Ditercalinium chloride
CAS:<p>Ditercalinium chloride, an anticancer agent, inhibits human DNA polymerase gamma activity and can deplete mitochondrial DNA in both mouse and human cells. Additionally, Ditercalinium chloride is a potential ligand against the COMMD10-AP3S1 fusion protein [1] [2].</p>Formula:C46H50Cl2N6O2Color and Shape:SolidMolecular weight:789.835-O-TBDMS-N4-Benzoyl-2-deoxycytidine
CAS:<p>5-O-TBDMS-N4-Benzoyl-2-deoxycytidine is a modified nucleoside utilized in the synthesis of deoxyribonucleic acid (DNA) or nucleic acid.</p>Formula:C22H31N3O5SiColor and Shape:SolidMolecular weight:445.58HDAC-IN-85
<p>HDAC-IN-85 (Compound 1) is an HDAC inhibitor capable of crossing the blood-brain barrier. It exhibits inhibitory effects on brain tumor cell lines and can induce acetylation, resulting in DNA double-strand breaks and promoting RAD51 ubiquitination, which disrupts the DNA repair process. HDAC-IN-85 is applicable in studies of glioblastoma.</p>Formula:C24H27FN4O5Color and Shape:SolidMolecular weight:470.49RNA binder 1
<p>RNA binder 1 (Compound 4b) is an RNA-binding agent capable of crossing the blood-brain barrier. It selectively binds to the G-quadruplex structure of the G4C2 repeat sequence RNA of the C9orf72 gene. This compound significantly reduces levels of the toxic polypeptides poly(GA) and poly(GP) in cells derived from amyotrophic lateral sclerosis (ALS) patients, while it has no significant impact on the antisense polypeptide poly(PR), demonstrating selectivity for sense RNA. RNA binder 1 is useful for studying ALS and frontotemporal dementia (FTD).</p>Formula:C22H20N10S2Color and Shape:SolidMolecular weight:488.13138POLRMT-IN-1
<p>POLRMT-IN-1 (compound S7) is an inhibitor of POLRMT, specifically utilized in cancer-related research.</p>Color and Shape:Odour SolidNusinersen
CAS:<p>Nusinersen (nusinersen) is a antisense oligonucleotide (ASO) for the treatment of pediatric and adult spinal muscular atrophy (SMA) and increases SMN proteinss.</p>Purity:98.62%Color and Shape:SolidN1-Methylpseudouridine-5′-triphosphate tetralithium
<p>N1-Methylpseudouridine-5′-triphosphate tetralithium, also known as 1-Methylpseudouridine-5′-triphosphate tetralithium, is a nucleobase-modified nucleotide.</p>Formula:C10H13Li4N2O15P3Color and Shape:SolidMolecular weight:521.9Carboxy-pyridostatin
CAS:<p>Carboxy-pyridostatin, as a fluorescent probe, can target G-quadruplex structures and trap cytoplasmic RNA G-quadruplex structures in cells.</p>Formula:C35H34N10O7Color and Shape:SolidMolecular weight:706.715'-O-DMT-ibu-dC
CAS:<p>5'-O-DMT-ibu-dC can be used in the synthesis of oligodeoxyribonucleotides.</p>Formula:C34H37N3O7Color and Shape:SolidMolecular weight:599.67ML-60218
CAS:<p>ML-60218 inhibits RNA pol III in yeast/humans with IC50s of 32/27 μM; disrupts and prevents viroplasms.</p>Formula:C19H15Cl2N3O2S2Purity:98.1%Color and Shape:SolidMolecular weight:452.3816,16-dimethyl Prostaglandin A1
CAS:<p>16,16-dimethyl Prostaglandin A1 is a useful organic compound for research related to life sciences.</p>Formula:C22H36O4Color and Shape:SolidMolecular weight:364.526Chrexanthomycin C
<p>Chrexanthomycin C, orally active, binds DNA (G4C2)4 G4, Kd 2.8 mM, potential in ALS research.</p>Formula:C31H24O15Color and Shape:SolidMolecular weight:636.51PAT-LM1
<p>PAT-LM1 is a human monoclonal antibody that targets NRB54/NONO. It is applicable in the study of hematological malignancies.</p>Color and Shape:Odour Liquid5'-O-DMT-Bz-rC
CAS:<p>5’-O-DMT-Bz-Rc is a modified nucleoside and can be used to synthesize DNA or RNA.</p>Formula:C37H35N3O8Color and Shape:SolidMolecular weight:649.695-Methylcytidine 5′-triphosphate trisodium
<p>5-Methylcytidine 5′-triphosphate trisodium (5-Methyl-CTP trisodium), a modified nucleoside triphosphate, enhances translational properties and stability, while</p>Formula:C10H15N3Na3O14P3Color and Shape:SolidMolecular weight:563.13M7G(3'-OMe-5')pppA(2'-OMe)
<p>M7G(3'-OMe-5')pppA(2'-OMe) is a cap analogue for mRNA synthesis in vitro.</p>Formula:C23H33N10O17P3Color and Shape:SolidMolecular weight:814.49GS-443902 trisodium
CAS:<p>GS-443902 trisodium, a strong RdRp blocker, inhibits RSV/HCV with IC50 of 1.1/5 μM and is Remdesivir's active form.</p>Formula:C12H16N5O13P3·xNaColor and Shape:SolidCytidine 5'-diphosphate trisodium salt
CAS:<p>CDP, a trisodium salt, helps synthesize DNA/RNA by aiding phosphoryl transfer from ATP to CMP via UMPK.</p>Formula:C9H15N3Na3O11P2Purity:99.55%Color and Shape:White Crystalline PowderMolecular weight:472.155'-O-TBDMS-dA
CAS:<p>5’-O-TBDMS-dA is a modified nucleoside and can be used to synthesize DNA or RNA.</p>Formula:C16H27N5O3SiColor and Shape:SolidMolecular weight:365.509Nitrosofolic acid
CAS:<p>Nitrosofolic acid is a folic acid derivaive.</p>Formula:C19H18N8O7Color and Shape:SolidMolecular weight:470.40Carboxy pyridostatin trifluoroacetate salt
<p>Carboxy pyridostatin trifluoroacetate salt exhibits higher molecular specificity for RNA over DNA G4s.</p>Formula:C37H35F3N10O9Purity:98%Color and Shape:SolidMolecular weight:820.73CTP Synthetase-IN-1 Ammonium salt
<p>CTP Synthetase-IN-1 Ammonium salt is a CTPS inhibitor with potential antibacterial, anti-inflammatory, and antitumor activity for the study of SARS-CoV-2 viral infections</p>Formula:C20H22F3N7O3S2Purity:99.97%Color and Shape:SolidMolecular weight:529.56RNA splicing modulator 1
CAS:<p>RNA Splicing Modulator 1 (Compound 233) is a modulator of RNA splicing, exhibiting an AC50 value of less than 100 nM [1].</p>Formula:C19H20N6OSColor and Shape:SolidMolecular weight:380.47Lorutengitide
CAS:<p>Lorutengitide is a transcription-regulating peptide with antiproliferative activity.</p>Formula:C30H50N8O12Color and Shape:SolidMolecular weight:714.764Xanthosine-5'-Triphosphate
CAS:<p>Xanthosine-5'-Triphosphate (5'-XTP), a nucleotide derived from the deamination of purine bases, plays a crucial role in various biological processes.</p>Formula:C10H15N4O15P3Color and Shape:SolidMolecular weight:524.164CSN5-IN-2
<p>CSN5-IN-2 (Compound 31) is a CSN5 inhibitor with an IC50 of 0.36 μM. It increases Cullin 1 neddylation levels in cancer cells and downregulates the expression of RAD51 and PD-L1. CSN5-IN-2 exhibits antitumor activity, which is enhanced when used in combination with Talazoparib.</p>Color and Shape:Odour SolidPseudorabies virus-IN-1
<p>Pseudorabies virus-IN-1 is a potent inhibitor of pseudorabies virus (PRV) with an EC50 of 0.29 nM, acting by targeting PRV deoxyribonucleic acid polymerase (DNA pol) to suppress PRV replication. It effectively inhibits PRV replication even at low concentrations (MIC80: 1.6-8 nM) and is useful for research on PRV infections.</p>Formula:C27H23ClF2N4O2Color and Shape:SolidMolecular weight:508.947
