Chromatin/Epigenetics
Chromatin/epigenetics inhibitors are compounds that modulate the structure and function of chromatin or interfere with epigenetic modifications, such as DNA methylation and histone modification. These inhibitors are essential tools for studying gene expression regulation and the role of epigenetics in diseases like cancer, neurological disorders, and developmental abnormalities. By targeting epigenetic processes, these inhibitors can alter gene expression patterns and offer new therapeutic avenues. At CymitQuimica, we provide a wide selection of high-quality chromatin/epigenetics inhibitors to support your research in molecular biology, genetics, and epigenetics.
Subcategories of "Chromatin/Epigenetics"
Found 2235 products of "Chromatin/Epigenetics"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
MS37452
CAS:<p>MS37452 is a competitive inhibitor of CBX7 chromodomain binding to H3K27me3 (Ki = 43 µM).</p>Formula:C22H26N2O5Purity:99.39%Color and Shape:SolidMolecular weight:398.45Pamiparib
CAS:<p>Pamiparib (BGB-290) is an orally active, potent, highly selective PARP inhibitor. It has potent PARP trapping, and capability to penetrate the brain.</p>Formula:C16H15FN4OPurity:99.69%Color and Shape:SolidMolecular weight:298.31EPZ005687
CAS:<p>EPZ005687 is a potent and selective inhibitor of EZH2.</p>Formula:C32H37N5O3Purity:97.06% - 99.64%Color and Shape:SolidMolecular weight:539.67Fluzoparib
CAS:<p>Fluzoparib (SHR3162) is a novel, potent, and orally available inhibitor of PARP, potentially for the treatment of solid tumours.</p>Formula:C22H16F4N6O2Purity:98.53% - 99.63%Color and Shape:SolidMolecular weight:472.4GSK199
CAS:<p>GSK199 is a selective PAD4 inhibitor(IC50 of 200 nM in the absence of calcium).</p>Formula:C24H29ClN6O2Purity:99.44%Color and Shape:SolidMolecular weight:468.98653-47 hydrochloride
CAS:<p>653-47 hydrochloride boosts CREB inhibition by 666-15 and weakly inhibits CREB itself (IC50: 26.3 μM).</p>Formula:C20H20Cl2N2O3Purity:99.14%Color and Shape:SolidMolecular weight:407.29AMI-1
CAS:<p>AMI-1 is an effective and selective Histone Methyltransferase (HMT) inhibitor (IC50: 3.0/8.8 μM, for yeast Hmt1p, and human PRMT1).</p>Formula:C21H14N2Na2O9S2Purity:97.53% - 99.9%Color and Shape:DrypowderMolecular weight:548.45Bobcat339
CAS:<p>Bobcat339 is a novel cytosine-based TET enzyme inhibitor (IC50s: 33/73 uM for TET1/2), but not DNMT3a, does not inhibit the DNA methyltransferase DNMT3a.</p>Formula:C16H12ClN3OPurity:97.79% - 99.24%Color and Shape:SolidMolecular weight:297.74Nicotinamide riboside chloride
CAS:<p>NR, also SRT647, is a B3 vitamin form; precursor to NAD+.</p>Formula:C11H15ClN2O5Purity:98.92% - 99.86%Color and Shape:SolidMolecular weight:290.7Nudifloramide
CAS:<p>Nudifloramide (1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxamide) is one of the end degradation products of nicotinamide-adenine dinucleotide (NAD).</p>Formula:C7H8N2O2Purity:99.7% - ≥95%Color and Shape:SolidMolecular weight:152.15PF-9363
CAS:<p>PF-9363 (CTX-3648) is a potent and high selective KAT6A/KAT6B inhibitor. PF-9363 can be used for the research of cancer.</p>Formula:C20H20N4O6SPurity:99.03% - 99.7%Color and Shape:SolidMolecular weight:444.46Anacardic Acid
CAS:<p>Anacardic Acid (6-pentadecylsalicylic Acid) is an effective inhibitor of p300 and p300/CBP-associated factor histone acetyltranferases.</p>Formula:C22H36O3Purity:97.47% - 99.87%Color and Shape:SolidMolecular weight:348.52Cerdulatinib
CAS:<p>Cerdulatinib (PRT2070) is an novel oral dual Syk/JAK inhibitor.</p>Formula:C20H27N7O3SPurity:98.74% - 99.49%Color and Shape:SolidMolecular weight:445.54CPI-637
CAS:<p>CPI-637 is a selective and cell-active benzodiazepinone CBP/EP300 bromodomain inhibitor.</p>Formula:C22H22N6OPurity:99.89% - 99.95%Color and Shape:SolidMolecular weight:386.45Upadacitinib
CAS:<p>Upadacitinib (ABT-494), a selective JAK1 inhibitor, is researched for autoimmune diseases; IC50: 43 nM.</p>Formula:C17H19F3N6OPurity:98.96% - 99.94%Color and Shape:SolidMolecular weight:380.371,5-Isoquinolinediol
CAS:<p>1,5-Isoquinolinediol, a PARP1 inhibitor (IC50: 0.39 μM), is used in DNA repair and cell death studies.</p>Formula:C9H7NO2Purity:98.29% - 99.35%Color and Shape:Of White To White PowderMolecular weight:161.16666-15
CAS:<p>666-15 is a selective CREB inhibitor with an IC50 of 81 nM. 666-15 can effectively inhibit the growth of breast cancer.Cost-effective and quality-assured.</p>Formula:C33H31Cl2N3O5Purity:99.41% - 99.88%Color and Shape:SolidMolecular weight:620.52Pyridone 6
CAS:<p>Pyridone 6, a selective JAK1/2/3 and Tyk2 inhibitor with IC50s: JAK1=15 nM, JAK2=1 nM, JAK3 (Ki=5 nM), Tyk2=1 nM; weakly binds other kinases (130 nM-10 μM).</p>Formula:C18H16FN3OPurity:97.1% - 98.74%Color and Shape:SolidMolecular weight:309.34Phthalazinone pyrazole
CAS:<p>Phthalazinone pyrazole: a potent, selective oral Aurora-A kinase inhibitor, overexpressed in tumors with oncogenic activity.</p>Formula:C18H15N5OPurity:97.03%Color and Shape:SolidMolecular weight:317.34WHI-P97
CAS:<p>WHI-P97 is a rationally designed potent inhibitor of JAK-3.</p>Formula:C16H13Br2N3O3Purity:99.93%Color and Shape:SolidMolecular weight:455.1GN44028
CAS:<p>GN44028 is a HIF-1 inhibitor with an IC50 of 14 nM, stopping HIF-1α activity but not mRNA or protein levels, or dimerization.</p>Formula:C18H15N3O2Purity:99.52%Color and Shape:SolidMolecular weight:305.33JQ-1 (carboxylic acid)
CAS:<p>JQ-1 (carboxylic acid) is a cell-permeable BRD4 inhibitor with IC50s of 77 nM for BRD4(1) and 33 nM for BRD4(2)</p>Formula:C19H17ClN4O2SPurity:99.14% - 99.9%Color and Shape:SolidMolecular weight:400.88TCS7010
CAS:<p>TCS7010 (Aurora A Inhibitor I) is a novel, potent, and selective inhibitor of Aurora A with IC50 of 3.4 nM in a cell-free assay.</p>Formula:C31H31ClFN7O2Purity:98.49% - 99.62%Color and Shape:SolidMolecular weight:588.07BD750
CAS:<p>BD750 is an effective immunosuppressant and a JAK3/STAT5 inhibitor, inhibits IL-2-induced JAK3/STAT5-dependent T cell proliferation(IC50 of 1.5 μM and 1.1 μM in</p>Formula:C14H13N3OSPurity:99.02%Color and Shape:SolidMolecular weight:271.34Remodelin hydrobromide
CAS:<p>Remodelin hydrobromide (Remodelin HBR) is a novel potent and selective inhibitor of the acetyl-transferase protein NAT10.</p>Formula:C15H15BrN4SPurity:97.22% - 99.84%Color and Shape:SolidMolecular weight:363.2752,6-Dichloro-N-(2-(cyclopropanecarboxamido)pyridin-4-yl)benzamide
CAS:<p>2,6-Dichloro-N-(2-(cyclopropanecarboxamido)pyridin-4-yl)benzamide (GDC046), a potent lead analog, has good kinase selectivity and physicochemical properties.</p>Formula:C16H13Cl2N3O2Purity:98.77%Color and Shape:SolidMolecular weight:350.2γ-Oryzanol
CAS:<p>γ-Oryzanol (Gamma-Oryzanol) is a natural nutrient extract isolated from rice bran oil that contains a mixture of sterols and ferulic acids, which may aid in the</p>Formula:C40H58O4Purity:mixture - mixtureColor and Shape:White Or White Crystalline Powder OdourlessMolecular weight:602.9AZ9482
CAS:<p>AZ9482, a potent PARP inhibitor with 2-piperazinyl-3-cyano-pyridine linkage, causes centrosome declustering in HeLa cells with an EC50 < 18 nM.</p>Formula:C26H22N6O2Purity:99.18% - 99.86%Color and Shape:SolidMolecular weight:450.49AT-9283 HCl
CAS:<p>AT-9283, a multi-targeted kinase inhibitor, is used potentially for the treatment of multiple myeloma.</p>Formula:C19H24ClN7O2Color and Shape:SolidMolecular weight:417.89Ro 31-8220 Mesylate
CAS:<p>Ro 31-8220 Mesylate (Bisindolylmaleimide IX mesylate) is a pan-PKC inhibitor, and also shows potent inhibition against MSK1, MAPKAP-K1b, S6K1, and GSK3β.</p>Formula:C25H23N5O2S·CH4O3SPurity:98.79% - 99.02%Color and Shape:SolidMolecular weight:553.65PF-06726304
CAS:<p>PF-06726304: potent EZH2 inhibitor, effective against tumors, Kis at 0.7 nM (wild-type) and 3.0 nM (Y641N mutant).</p>Formula:C22H21Cl2N3O3Purity:98.19% - 99.51%Color and Shape:SolidMolecular weight:446.33BRD4 Inhibitor 30
CAS:<p>4-(2-fluorophenyl)-1,3-thiazol-2-one: has anti-inflammatory, antibacterial, antifungal, and antitumor properties.</p>Formula:C9H6FNOSPurity:99.68%Color and Shape:SolidMolecular weight:195.21WM-8014
CAS:<p>WM-8014 (MOZ-IN-3) is an inhibitor of MOZ(IC50=55 nM), a member of histone acetyltransferases.</p>Formula:C20H17FN2O3SPurity:99.64%Color and Shape:SolidMolecular weight:384.42PKC-iota inhibitor 1
CAS:<p>PKC-iota inhibitor 1 is an inhibitor of protein kinase C-iota (PKC-ι ; IC50 : 0.34 μM)</p>Formula:C21H22N6OPurity:98.82%Color and Shape:SolidMolecular weight:374.44Ilorasertib
CAS:<p>Ilorasertib (ABT-348) inhibits Aurora kinases A/B/C & RET, PDGFRβ, Flt1 (IC50: 1-120 nM).</p>Formula:C25H21FN6O2SPurity:96.17% - 97.49%Color and Shape:SolidMolecular weight:488.54Chlorogenic Acid
CAS:<p>Chlorogenic acid is a natural phenol. Chlorogenic acid has anti-inflammatory, antitumor, and antimicrobial effects. Cost-effective and quality-assured.</p>Formula:C16H18O9Purity:98.84% - 99.67%Color and Shape:SolidMolecular weight:354.31GSK484 hydrochloride
CAS:<p>GSK484 hydrochloride (GTPL8577) is a reversible peptidyl-arginine deiminase 4 (PAD4) inhibitor.Cost-effective and quality-assured.</p>Formula:C27H32ClN5O3Purity:98.32% - 99.62%Color and Shape:SolidMolecular weight:510.03JNJ-42041935
CAS:<p>JNJ-42041935 (HIF-PHD Inhibitor II) is a potent (pKi = 7.3-7.9), 2-oxoglutarate competitive, reversible, and selective inhibitor of PHD enzymes.</p>Formula:C12H6ClF3N4O3Purity:99.58% - ≥95%Color and Shape:SolidMolecular weight:346.65UPF 1069
CAS:<p>UPF 1069 is a specific PARP2 inhibitor ( IC50: 0.3 μM). It is ~27-fold selective against PARP1.</p>Formula:C17H13NO3Purity:98.80% - 99.88%Color and Shape:SolidMolecular weight:279.29HJ-PI01
CAS:<p>HJ-PI01 (HJ-PI01) is a Pim-2 inhibitor. HJ-PI01 (HJ-PI01) induces apoptosis and autophagic cell death in triple-negative human breast cancer.</p>Formula:C14H11NO2Purity:98.92%Color and Shape:SolidMolecular weight:225.24GSK-J1
CAS:<p>GSK-J1 is a highly potent H3K27 histone demethylase inhibitor with IC50 of 28 nM and 53 nM in cell-free assays for JMJD3 (KDM6B) and UTX (KDM6A), respectively.</p>Formula:C22H23N5O2Purity:99.23% - 99.67%Color and Shape:SolidMolecular weight:389.45PJ34 hydrochloride
CAS:<p>PJ34 hydrochloride (PJ34 HCl) is a potent specific inhibitor of PARPl/2.</p>Formula:C17H18ClN3O2Purity:98.87% - ≥95%Color and Shape:SolidMolecular weight:331.8NCGC00244536
CAS:<p>NCGC00244536 (KDM4B Inhibitor B3) is a potent KDM4B inhibitor (IC50: 10 nM).</p>Formula:C25H22N2O2Purity:97.2% - 99.72%Color and Shape:SolidMolecular weight:382.45SAR-20347
CAS:<p>SAR-20347 is an inhibitor of TYK2, JAK1/2/3 (IC50: 0.6/23/26/41 nM).</p>Formula:C21H18ClFN4O4Purity:98.99% - 99.77%Color and Shape:SolidMolecular weight:444.84Lomeguatrib
CAS:<p>Lomeguatrib (PaTrin-2), a modified guanine base, inhibits the activity of DNA repair protein O(6)-alkylguanine-DNA alkyltransferase (MGMT) .</p>Formula:C10H8BrN5OSPurity:99.26% - >99.99%Color and Shape:SolidMolecular weight:326.17WHI-P97 HCl
<p>WHI-P97 HCl is a potent and selective JAK-3 inhibitor.</p>Formula:C16H14Br2ClN3O3Purity:99.49%Color and Shape:SolidMolecular weight:491.56Hesperadin
CAS:<p>Hesperadin(IC50=250 nM) effectively inhibits Aurora B.</p>Formula:C29H32N4O3SPurity:98.04% - 99.44%Color and Shape:SolidMolecular weight:516.65Selisistat
CAS:<p>Selisistat (EX-527) is a potent and specific inhibitor of the deacetylase SIRT1 (IC50=38 nM).</p>Formula:C13H13ClN2OPurity:98.53% - 99.94%Color and Shape:SolidMolecular weight:248.71Methyl L-histidinate dihydrochloride
CAS:<p>The inhibitory effect of Methyl L-histidinate dihydrochloride (L-Histidine methyl ester dihydrochloride) on histidine decarboxylase in Sprague-Dawley rat</p>Formula:C7H13Cl2N3O2Purity:99.74%Color and Shape:White To Off-White PowderMolecular weight:242.1A-196
CAS:<p>A-196 is a potent and selective inhibitor of SUV420 h1 and SUV420 h2 with IC50 values of 0.025 and 0.144 μM, respectively; more than 100-fold selective over</p>Formula:C18H16Cl2N4Purity:99.92%Color and Shape:SolidMolecular weight:359.253-TYP
CAS:<p>3-TYP (3-(1H-1,2,3-triazol-4-yl) pyridine) is a selective SIRT3 inhibitor.</p>Formula:C7H6N4Purity:99.16% - >99.99%Color and Shape:SolidMolecular weight:146.15Splitomicin
CAS:<p>Splitomicin (1-Naphthalenepropanoic Acid) (IC50 of 60 μM), a specific inhibitor of NAD(+)-dependent histone deacetylase Sir2p, displays a high activity in a</p>Formula:C13H10O2Purity:97.09% - 99.11%Color and Shape:SolidMolecular weight:198.224-Phenylbutyric acid
CAS:<p>4-Phenylbutyric acid (Benzenebutyric acid) is a HDAC inhibitor and an endoplasmic reticulum stress (ERS) inhibitor. Cost-effective and quality-assured.</p>Formula:C10H12O2Purity:98.40% - 99.76%Color and Shape:SolidMolecular weight:164.2dencichine
CAS:<p>Dencichine (ODAP) is a neurotoxic agent and a haemostatic agent, which relates to modulation of the coagulation system, and fibrinolytic system.</p>Formula:C5H8N2O5Purity:99.93% - ≥95%Color and Shape:SolidMolecular weight:176.13CPI-455
CAS:<p>CPI-455 is a specific KDM5 inhibitor.</p>Formula:C16H14N4OPurity:97.87% - 99.03%Color and Shape:SolidMolecular weight:278.31BAZ1A-IN-1
CAS:<p>BAZ1A-IN-1, a potent inhibitor, KD 0.52 μM against BAZ1A, is effective in high-BAZ1A cancer cells, not in low-BAZ1A ones.</p>Formula:C16H12N4O3SPurity:99.87%Color and Shape:SolidMolecular weight:340.36I-CBP112
CAS:<p>I-CBP112 is a specific and potent acetyl-lysine competitive protein-protein interaction inhibitor targeting the CBP/p300 bromodomains.</p>Formula:C27H36N2O5Purity:98.18%Color and Shape:SolidMolecular weight:468.59MI-503
CAS:<p>MI-503 is an efficient and selective Menin-MLL inhibitor. MI-503 has a significant inhibitory effect on human MLL leukemia cell line. Cost-effective and quality-assured.</p>Formula:C28H27F3N8SPurity:99.87% - 99.99%Color and Shape:SolidMolecular weight:564.63AZD1208
CAS:<p>AZD1208 is a novel, orally bioavailable, highly selective PIM kinase inhibitor with single nanomolar potency against all three PIM kinases.</p>Formula:C21H21N3O2SPurity:97.24% - 99.83%Color and Shape:SolidMolecular weight:379.48Niraparib hydrochloride
CAS:<p>Niraparib hydrochloride (MK-4827) is a PARP inhibitor with potential cancer treatment effects, causing DNA damage and apoptosis.</p>Formula:C19H21ClN4OPurity:99.26%Color and Shape:SolidMolecular weight:356.85B2
CAS:<p>B2 (Linazolamide intermediate B impurity 2) promotes inclusion formation in cellular models of Huntington's disease and Parkinson's disease</p>Formula:C20H17ClN4O3Purity:99.66%Color and Shape:SolidMolecular weight:396.83C-7280948
CAS:<p>C-7280948 is a PRMT1 inhibitor.</p>Formula:C14H16N2O2SPurity:99.55% - ≥95%Color and Shape:SolidMolecular weight:276.35Birabresib
CAS:<p>Birabresib (MK-8628) is a synthetic, small molecule inhibitor of the BET (Bromodomain and Extra-Terminal) family of bromodomain-containing proteins 2, 3 and 4</p>Formula:C25H22ClN5O2SPurity:98.3% - 99.36%Color and Shape:SolidMolecular weight:491.99Amodiaquine
CAS:<p>Amodiaquine is a synthetic aminoquinoline, used to treat malaria.</p>Formula:C20H22ClN3OPurity:99.78% - 99.99%Color and Shape:Crystals From Absolute Ethanol SolidMolecular weight:355.86DMOG
CAS:<p>DMOG (Dimethyloxalylglycine), an antagonist of the α-ketoglutarate cofactor, is an inhibitor for HIF prolyl hydroxylase.</p>Formula:C6H9NO5Purity:80.23% - 99.98%Color and Shape:SolidMolecular weight:175.14MR837
CAS:<p>MR837 (NSD2-PWWP1 antagonist 3f) is a NSD2-PWWP1 antagonist.</p>Formula:C16H14N2OSPurity:99.77% - 99.85%Color and Shape:SolidMolecular weight:282.36MK-8617
CAS:<p>MK-8617 is an orally available HIF PHD1 3 pan-inhibitor, inhibiting PHD1/2/3 (IC50: 1.0/1.0/14 nM).</p>Formula:C24H21N5O4Purity:99.38% - >99.99%Color and Shape:SolidMolecular weight:443.45NVP-TNKS656
CAS:<p>NVP-TNKS656 (TNKS656) is a highly potent, selective, and orally active TNKS2 inhibitor.</p>Formula:C27H34N4O5Purity:99.59%Color and Shape:SolidMolecular weight:494.58RBN012759
CAS:<p>RBN012759 inhibits PARP14 protein and is more than 300-fold selective over all PARP family members.Cost-effective and quality-assured.</p>Formula:C19H23FN2O3SPurity:98.87% - 99.96%Color and Shape:SolidMolecular weight:378.461,2-Dipalmitoyl-sn-glycerol
CAS:<p>1,2-Dipalmitoyl-sn-glycerol ((S)-1,2-Dipalmitin) is an analog of the PKC-activating second messenger diacylglycerol (DAG). It weakly activates PKC.</p>Formula:C35H68O5Purity:97.84% - 99.78%Color and Shape:SolidMolecular weight:568.91Atractylenolide I
CAS:<p>Atractylenolide-I reduces inflammation, improves sepsis, liver, and kidney function, and enhances EOC cell sensitivity to paclitaxel.</p>Formula:C15H18O2Purity:97.55% - 99.92%Color and Shape:SolidMolecular weight:230.3MI-463
CAS:<p>MI-463 is a potent and orally bioavailable inhibitor of the menin-mLL interaction (IC50: 15.3 nM).</p>Formula:C24H23F3N6SPurity:99.18% - >99.99%Color and Shape:SolidMolecular weight:484.54KC7F2
CAS:<p>KC7F2 is a potent HIF-1 pathway inhibitor with potential anti-cancer activity.</p>Formula:C16H16Cl4N2O4S4Purity:98% - 99.11%Color and Shape:SolidMolecular weight:570.38GLPG0634 analog
CAS:<p>GLPG0634 analog (GLPG0634 analogue) is a specific JAK1 inhibitor with IC50 of 10/28/810/116 nM for JAK1/2/3 and TYK2, respectively.</p>Formula:C23H18N6O2Purity:99.52% - >99.99%Color and Shape:SolidMolecular weight:410.43ABBV-744
CAS:<p>ABBV-744 is a BDII-selective BET bromodomain inhibitor that inhibits BRD2/3/4. It is used in the research on inflammatory diseases, cancer, and AIDS.</p>Formula:C28H30FN3O4Purity:97.03% - >99.99%Color and Shape:SolidMolecular weight:491.55BRD4770
CAS:<p>BRD4770 is a histone methyltransferase G9a inhibitor and induces cell senescence.</p>Formula:C25H23N3O3Purity:99.82%Color and Shape:SolidMolecular weight:413.47CYC-116
CAS:<p>CYC116 is a potent inhibitor of Aurora A/B with Ki of 8.0 nM/9.2 nM, is less potent to VEGFR2 (Ki of 44 nM), with 50-fold greater potency than CDKs, not active</p>Formula:C18H20N6OSPurity:97.36% - 97.59%Color and Shape:SolidMolecular weight:368.46ORY1001
CAS:<p>ORY1001: Oral LSD1/KDM1A inhibitor, highly selective, IC50 <20 nM.</p>Formula:C15H22N2·2HClPurity:99.85% - 99.96%Color and Shape:SolidMolecular weight:303.27XL019
CAS:<p>XL019 is a potent and selective JAK2 inhibitor with IC50 of 2.2 nM, 100 fold selectivity over JAK1.</p>Formula:C25H28N6O2Purity:99.19%Color and Shape:SolidMolecular weight:444.53GSK1324726A
CAS:<p>GSK1324726A (I-BET726) is a greatly specific inhibitor of BET family proteins for BRD2(IC50=41 nM), BRD3(IC50=31 nM), and BRD4 (IC50=22 nM).</p>Formula:C25H23ClN2O3Purity:98.34% - 99.85%Color and Shape:SolidMolecular weight:434.91Picolinamide
CAS:<p>Picolinamide (Picolinoylamide) is found to be a strong inhibitor of poly (ADP-ribose) synthetase of nuclei from rat pancreatic islet cells.</p>Formula:C6H6N2OPurity:99.6%Color and Shape:SolidMolecular weight:122.12MS049
CAS:<p>MS 049 is a potent, selective, and cell-active dual inhibitor of PRMT4 and PRMT6 with IC 50 of 34 nM and 43 nM, respectively.</p>Formula:C15H24N2OPurity:98.91%Color and Shape:SolidMolecular weight:248.36TCS-PIM-1-4a
CAS:<p>SMI-4a, a Pim inhibitor, activates AMPK, halts mTORC1, and kills various myeloid/lymphoid cells (IC50=0.8-40μM).</p>Formula:C11H6F3NO2SPurity:99.89%Color and Shape:SolidMolecular weight:273.23MS023
CAS:<p>MS023 is a potent, selective, and cell-active Type I PRMT inhibitor with IC50 of 30 nM, 119 nM, 83 nM, 4 nM, and 5 nM for PRMT1, PRMT3, PRMT4, PRMT6 and PRMT8,</p>Formula:C17H25N3OPurity:98.31% - 99.87%Color and Shape:SolidMolecular weight:287.4GSK121
CAS:<p>GSK121 is an inhibitor of selective PAD4.</p>Formula:C25H26F3N5O3Purity:98.92%Color and Shape:SolidMolecular weight:501.51PJ34
CAS:<p>PJ34 HCl is the hydrochloride salt of PJ34, which is a PARP inhibitor with EC50 of 20 nM and is equally potent to PARP1/2.</p>Formula:C17H17N3O2Purity:95.05% - 99.85%Color and Shape:SolidMolecular weight:295.34HIF-2α-IN-4
CAS:<p>HIF-2a translation inhibitor is a compound used as a molecular building block.</p>Formula:C9H9N3O4S2Purity:≥98%Color and Shape:SolidMolecular weight:287.32SP-146
<p>SP-146 is a selective, potent and non-ATP-competitive Aurora B inhibitor(IC50 : 0.316 nM).</p>Formula:C25H20FN7OPurity:97.82%Color and Shape:SolidMolecular weight:453.47Piribedil
CAS:<p>Piribedil (Trivastan) is a dopamine D2 agonist, used in the treatment of Parkinson's disease.</p>Formula:C16H18N4O2Purity:99.79% - 99.82%Color and Shape:SolidMolecular weight:298.34dBET1
CAS:<p>dBET1 fuses (+)-JQ1 with thalidomide, degrades BET proteins via cereblon (EC50: 430 nM), and triggers apoptosis.</p>Formula:C38H37ClN8O7SPurity:98.02% - 99.3%Color and Shape:SolidMolecular weight:785.27ZM39923 hydrochloride
CAS:<p>ZM39923 hydrochloride (JAK3 Inhibitor IV) is an JAK1/3 inhibitor, almost no activity to JAK2 and modestly potent to EGFR; also is sensitive to transglutaminase.</p>Formula:C23H25NO·HClPurity:98.05%Color and Shape:SolidMolecular weight:367.91MK-8745
CAS:<p>MK-8745 is a potent and selective Aurora A inhibitor.</p>Formula:C20H19ClFN5OSPurity:99.09% - 99.79%Color and Shape:SolidMolecular weight:431.91JANEX-1
CAS:<p>JANEX-1: cell-permeable, reversible Jak3 inhibitor (IC50: 78 μM), ATP-competitive, selective; weak on JAK1/2, Zap/Syk, SRC.</p>Formula:C16H15N3O3Purity:98% - 99.81%Color and Shape:SolidMolecular weight:297.31SGC2085
CAS:<p>SGC2085 is an effective and selective coactivator-associated arginine methyltransferase 1 (CARM1) inhibitor (IC50: 50 nM).</p>Formula:C19H24N2O2Purity:99.61% - 99.71%Color and Shape:SolidMolecular weight:312.41CPI-1205
CAS:<p>CPI-1205 是一种高效的选择性 EZH2 抑制剂（IC50：0.002 μM，EC50：0.032 μM）。</p>Formula:C27H33F3N4O3Purity:98.71% - 99.7%Color and Shape:SolidMolecular weight:518.57DCLX069
CAS:<p>DCLX069: PRMT1 inhibitor, IC50=17.9µM, targets SAM pocket, inhibits breast/liver cancer, and AML cell growth.</p>Formula:C20H25N3O2Purity:97.76%Color and Shape:SolidMolecular weight:339.43AZD5305
CAS:<p>AZD5305 is a potent, selective and oral active PARP inhibitor.</p>Formula:C22H26N6O2Purity:98.68% - 99.93%Color and Shape:SolidMolecular weight:406.48Peficitinib
CAS:<p>Peficitinib (ASP015K) (ASP015K, JNJ-54781532) is an orally bioavailable JAK inhibitor. Phase 3.</p>Formula:C18H22N4O2Purity:98.67% - 99.4%Color and Shape:SolidMolecular weight:326.39E-7386
CAS:<p>E-7386 is an oral active CBP/ -catenin modulator.</p>Formula:C39H48FN9O4Purity:98.92% - 99.91%Color and Shape:SolidMolecular weight:725.85Olaparib
CAS:<p>View and buy Olaparib from TargetMol.Olaparib is a small molecule inhibitor of PARP1/PARP2.Cited in 10 publications.</p>Formula:C24H23FN4O3Purity:98% - >99.99%Color and Shape:SolidMolecular weight:434.46TP-3654
CAS:<p>TP-3654 is a second-generation Pim kinase inhibitor (Ki values against Pim-1/3: 5/42 nM).</p>Formula:C22H25F3N4OPurity:99.8% - 99.95%Color and Shape:SolidMolecular weight:418.46E7449
CAS:<p>E7449 is a potent inhibitor of PARP1, PARP2, TNKS1, and TNKS2 with IC50s of 2, 1, ~50, and ~50 nM respectively.</p>Formula:C18H15N5OPurity:97.13%Color and Shape:SolidMolecular weight:317.34Protosappanin A
CAS:<p>Protosappanin A combats brain inflammation, suppresses rat heart transplant rejection, fights MRSA, and inhibits HIV with a 12.6 uM IC50.</p>Formula:C15H12O5Purity:99.42% - 99.82%Color and Shape:SolidMolecular weight:272.25Molibresib
CAS:<p>Molibresib (GSK525762) is an inhibitor of BET proteins (IC50: about 35 nM).</p>Formula:C22H22ClN5O2Purity:97.70% - 99.08%Color and Shape:SolidMolecular weight:423.9(+)-JQ1 PA
CAS:<p>(+)-JQ1 PA is a derivative of the Bromodomain and extra-terminal (BET) inhibitor JQ1(IC50 of 10.4 nM).</p>Formula:C22H20ClN5OSPurity:98.36%Color and Shape:SolidMolecular weight:437.95WM-1119
CAS:<p>WM-1119 is a highly potent, selective KAT6A/B inhibitor</p>Formula:C18H13F2N3O3SPurity:96.59% - 99.58%Color and Shape:SolidMolecular weight:389.38XD14
CAS:<p>XD14 inhibits BET bromodomains with Kd: BRD4(1) 160nM, BRD2(1) 170nM, BRD3(1) 380nM, BRD3(2) 490nM, BRD2(2) 830nM, BRD4(2) 850nM.</p>Formula:C20H27N3O5SPurity:97.46%Color and Shape:SolidMolecular weight:421.51FL-411
CAS:<p>FL-411 (BRD4-IN-1) is a potent and selective BRD4 inhibitor with an IC50 of 0.43±0.09 μM for BRD4.</p>Formula:C18H19N3O2SPurity:98.19%Color and Shape:SolidMolecular weight:341.43GSK3685032
CAS:<p>GSK3685032 is a non-covalent and selective DNMT1 inhibitor(IC50 = 36 nM).</p>Formula:C22H24N6OSPurity:98.56% - 99.49%Color and Shape:SolidMolecular weight:420.53Daminozide
CAS:<p>Daminozide (Succinic Acid) is a plant growth regulator, selectively inhibits the KDM2/7 JmjC subfamily.</p>Formula:C6H12N2O3Purity:99.86%Color and Shape:White Crystalline Solid Physical Description Odorless White Crystals Or Powder (Ntp 1992)Molecular weight:160.17GSK-5959
CAS:<p>GSK-5959 is a selective BRPF1 inhibitor with IC50 ~80 nM, 100-fold more specific than 35 other bromodomains.</p>Formula:C22H26N4O3Purity:98.35% - 98.65%Color and Shape:SolidMolecular weight:394.47Deucravacitinib
CAS:<p>Deucravacitinib (BMS-986165) is a highly selective, orally bioavailable, allosteric TYK2 inhibitor.Cost-effective and quality-assured.</p>Formula:C20H19D3N8O3Purity:98.52% - >99.99%Color and Shape:SolidMolecular weight:425.46Momelotinib
CAS:<p>Momelotinib (LM-1149), an oral JAK1/2 inhibitor with IC50s 11/18 nM, blocks ATP binding, disrupting JAK-STAT pathway and reducing tumor growth.</p>Formula:C23H22N6O2Purity:97.47% - 99.56%Color and Shape:SolidMolecular weight:414.46MS436
CAS:<p>MS436 is a selective, small-molecule inhibitor for the BRD4 bromodomains.</p>Formula:C18H17N5O3SPurity:97.95% - 98.92%Color and Shape:SolidMolecular weight:383.42SNS-314 Mesylate
CAS:<p>SNS-314 Mesylate (SNS-314) is an effective and specific Aurora A/B/C inhibitor. SNS-314 is less inhibition of Trk A/B, Fms, Flt4, c-Raf, Axl, and DDR2.</p>Formula:C18H15ClN6OS2·CH4O3SPurity:99.44% - 99.92%Color and Shape:SolidMolecular weight:527.04BAY-598
CAS:<p>BAY 598 is a potent and selective competitive inhibitor of SMYD2, exhibiting >100-fold selectivity over SMYD3, SUV420H1, and SUV420H2. Cost-effective and quality-assured.</p>Formula:C22H20Cl2F2N6O3Purity:99.18% - 99.78%Color and Shape:SolidMolecular weight:525.342',3',5'-triacetyl-5-Azacytidine
CAS:<p>2',3',5'-triacetyl-5-Azacytidine (Nsc291930) is a prodrug form of 5-azacytidine that may be rapidly absorbed orally.</p>Formula:C14H18N4O8Purity:98.34%Color and Shape:SolidMolecular weight:370.31GSK046
CAS:<p>GSK046 (iBET-BD2), potent oral BET BD2 inhibitor; IC50: BRD2 (264 nM), BRD3 (98 nM), BRD4 (49 nM), BRDT (214 nM); immunomodulatory.</p>Formula:C23H27FN2O4Purity:99.97%Color and Shape:SolidMolecular weight:414.47RO495
CAS:<p>RO495 (CS-2667), a potent inhibitor of TYK2, inhibits TYK2 with IC50 of 1.5nM as tested in cell-based pharmacological assays</p>Formula:C17H14Cl2N6OPurity:97.94%Color and Shape:SolidMolecular weight:389.24GSK6853
CAS:<p>GSK6853 is a potent, soluble, cell-active, and highly selective inhibitor of the BRPF1 bromodomain.</p>Formula:C22H27N5O3Purity:98.71% - 99.21%Color and Shape:SolidMolecular weight:409.48(Z)-LFM-A13
CAS:<p>(Z)-LFM-A13(IC50=2.5 μM), a specific Bruton's tyrosine kinase (BTK), is more than 100-fold specificity than other protein kinases, such as JAK1, JAK2, HCK, EGFR, and IRK.</p>Formula:C11H8Br2N2O2Purity:99.88%Color and Shape:SolidMolecular weight:360Niraparib
CAS:<p>Niraparib (MK-4827) inhibits PARP1/PARP2 (IC50: 3.8/2.1 nM), effective on BRCA mutant cancers, 330x less effective on PARP3, V-PARP, Tank1.</p>Formula:C19H20N4OPurity:98% - 99.91%Color and Shape:SolidMolecular weight:320.39AKBA
CAS:<p>AKBA (3-O-Acetyl-11-keto-beta-boswellic acid), a natural component from frankincense, is a novel activator of Nrf2.</p>Formula:C32H48O5Purity:97.85% - 99.77%Color and Shape:SolidMolecular weight:512.72MN-64
CAS:<p>MN-64 is a tankyrases inhibitor, showed 6 nM potency against tankyrase 1, isoenzyme selectivity, and Wnt signaling inhibition.</p>Formula:C18H16O2Purity:99.5% - 99.93%Color and Shape:SolidMolecular weight:264.32SGC0946
CAS:<p>SGC0946 is a highly effective and specific DOT1L methyltransferase inhibitor (IC50: 0.3 nM); selectively kill mixed lineage leukemia cells.</p>Formula:C28H40BrN7O4Purity:98% - 99.82%Color and Shape:SolidMolecular weight:618.57SMI-16a
CAS:<p>SMI-16a (PIM1/2 Kinase Inhibitor VI) , a cell-permeable thiazolidinedione compound, acts as an effective, ATP-competitive inhibitor against Pim-1/2 kinases (</p>Formula:C13H13NO3SPurity:99.99%Color and Shape:SolidMolecular weight:263.31OF-1
CAS:<p>OF-1 is a potent inhibitor of BRPF1B and BRPF2 bromodomain.</p>Formula:C17H18BrN3O4SPurity:98.55% - ≥95%Color and Shape:SolidMolecular weight:440.31AT9283
CAS:<p>AT9283 (J-504568) is an effective multi-targeted inhibitor of JAK2(IC50=1.2 nM) and JAK3(IC50=1.1 nM), Aurora A, Aurora B and Abl(T315I).</p>Formula:C19H23N7O2Purity:99.83% - 99.98%Color and Shape:SolidMolecular weight:381.43SETDB1-TTD-IN-1
CAS:<p>SETDB1-TTD-IN-1 is a potent and selective inhibitor of SET domain bifurcated protein 1 tandem tudor domain (SETDB1-TTD, Kd = 88 nM).Cost-effective and quality-assured.</p>Formula:C28H31N5O2Purity:98.26% - 99.96%Color and Shape:SolidMolecular weight:469.58JMJD7-IN-1
CAS:<p>JMJD7-IN-1 (Benzoic acid, 2,4-dichloro-, 5-nitro-8-quinolinyl ester) is a potent JMJD7 inhibitor, with an IC50 of 6.62 μM.</p>Formula:C16H8Cl2N2O4Purity:99.66%Color and Shape:SolidMolecular weight:363.15PF-9366
CAS:<p>PF-9366 is a human methionine adenosyltransferase 2A (Mat2A) inhibitor (IC50: 420 nM; Kd: 170 nM).</p>Formula:C20H19ClN4Purity:97.28% - 99.88%Color and Shape:SolidMolecular weight:350.84AG-270
CAS:<p>AG-270 is an allosteric and orally active inhibitor of MAT2A.</p>Formula:C30H27N5O2Purity:98.28% - 98.87%Color and Shape:SolidMolecular weight:489.57C-82
CAS:<p>C-82 is a specific CBP/β-catenin antagonist. It inhibits the binding between β-catenin and CBP and increases the binding between β-catenin and p300.</p>Formula:C33H34N6O4Purity:98.86% - 99.66%Color and Shape:SolidMolecular weight:578.66Itacitinib
CAS:<p>Itacitinib (INCB039110) is an orally bioavailable inhibitor of Janus-associated kinase 1 (JAK1) with potential antineoplastic activity.</p>Formula:C26H23F4N9OPurity:96.4% - 99.5%Color and Shape:SolidMolecular weight:553.51A-966492
CAS:<p>A-96649 is a new-type and effective inhibitor. The Ki of A-966492 for PARP1 and PARP2 is 1 nM and 1.5 nM, respectively.</p>Formula:C18H17FN4OPurity:98.53% - 99.27%Color and Shape:SolidMolecular weight:324.35GSK503
CAS:<p>GSK-503, a potent EZH2 inhibitor, has potential antitumor activity.</p>Formula:C31H38N6O2Purity:98% - 99.89%Color and Shape:SolidMolecular weight:526.67PFI-4
CAS:<p>PFI-4 is a potent and selective and cell-permeable BRPF1 bromodomain inhibitor.</p>Formula:C21H24N4O3Purity:99.53% - ≥95%Color and Shape:SolidMolecular weight:380.44NI-57
CAS:<p>NI-57 inhibits BRPF family proteins: BRPF1 (IC50=3.1nM), BRPF2 (IC50=46nM), BRPF3 (IC50=140nM).</p>Formula:C19H17N3O4SPurity:99.88% - >99.99%Color and Shape:SolidMolecular weight:383.42Menin-MLL inhibitor MI-2
CAS:<p>Menin-MLL inhibitor MI-2 (MI2) is a potent menin-MLL interaction inhibitor with IC50 of 446 nM.</p>Formula:C18H25N5S2Purity:97.46%Color and Shape:SolidMolecular weight:375.55Molibresib besylate
CAS:<p>Molibresib besylate (GSK 525762C) is a BET protein family inhibitor used in the study of refractory hematologic malignant diseases.</p>Formula:C28H28ClN5O5SPurity:99.64% - 99.64%Color and Shape:SolidMolecular weight:582.07Oroxylin A
CAS:<p>Oroxylin A fights tumors, aids RAS therapy, promotes CaCo-2 cell apoptosis, blocks MCF-7 cell invasion and enhances leukemia treatment.</p>Formula:C16H12O5Purity:98.72% - 99.55%Color and Shape:SolidMolecular weight:284.26Tofacitinib
CAS:<p>Tofacitinib (Tasocitinib) is an orally Janus kinase inhibitor. Tofacitinib is used for the treatment of rheumatoid arthritis. Cost effective and quality assured.</p>Formula:C16H20N6OPurity:99% - >99.99%Color and Shape:SolidMolecular weight:312.37GSK126
CAS:<p>GSK126 (GSK2816126A) is a excellently specific EZH2 methyltransferase inhibitor ( IC50=9.9 nM).</p>Formula:C31H38N6O2Purity:98% - 99.67%Color and Shape:SolidMolecular weight:526.67Seclidemstat
CAS:<p>Seclidemstat (SP-2577) is an effective LSD1 inhibitor, with a mean IC50 of 127 nM.</p>Formula:C20H23ClN4O4SPurity:98.28% - 99.76%Color and Shape:SolidMolecular weight:450.94Veliparib dihydrochloride
CAS:<p>Veliparib dihydrochloride (ABT-888 dihydrochloride) is a potent inhibitor of PARP1 and PARP2 with Ki of 5.2 nM and 2.9 nM in cell-free assays, respectively.</p>Formula:C13H18Cl2N4OPurity:98% - 99.81%Color and Shape:SolidMolecular weight:317.21Remodelin
CAS:<p>Remodelin is an effective and specific inhibitor of the acetyl-transferase protein NAT10.</p>Formula:C15H14N4SPurity:99.39% - 99.83%Color and Shape:SolidMolecular weight:282.363PT-2385
CAS:<p>PT-2385 is a selective HIF-2α inhibitor (Kd<50 nM).</p>Formula:C17H12F3NO4SPurity:98.91% - 99.55%Color and Shape:SolidMolecular weight:383.34Venadaparib
CAS:<p>Venadaparib, a PARP inhibitor (IC50: 1.4/1.0 nM for PARP1/2), is orally active, selective, not affecting PARP-5, used in tumor studies.</p>Formula:C23H23FN4O2Purity:99.86%Color and Shape:SolidMolecular weight:406.45RN-1 dihydrochloride
CAS:<p>RN-1 dihydrochloride is an effective and selective irreversible inhibitor of lysine-specific demethylase 1 (LSD1, IC50 = 70 nM).</p>Formula:C23H31Cl2N3O2Purity:99.64%Color and Shape:SolidMolecular weight:452.42Ruxolitinib
CAS:<p>Ruxolitinib (INCB018424) is a JAK1/2 inhibitor (IC50=3.3/2.8 nM) that is potent and selective.</p>Formula:C17H18N6Purity:99.4% - >99.99%Color and Shape:SolidMolecular weight:306.36GSK2801
CAS:<p>GSK2801 is an effective, specific and cell active acetyl-lysine competitive inhibitor of BAZ2A(Kd: 136 nM) and BAZ2B(Kd: 257 nM) bromodomains.</p>Formula:C20H21NO4SPurity:97.78% - 99.45%Color and Shape:SolidMolecular weight:371.455-Methyl-2'-deoxycytidine
CAS:<p>5-Methyl-2'-deoxycytidine (5MedCyd) is a pyrimidine nucleoside that when incorporated into single-stranded DNA can act in cis to signal de novo.</p>Formula:C10H15N3O4Purity:99.18% - 99.69%Color and Shape:SolidMolecular weight:241.242-methyl-2,3,4,5-tetrahydro-1,5-benzothiazepin-4-one
CAS:<p>2-methyl-2,3-dihydro-1,5-benzothiazepin-4(5H)-one is ligand of CBP.</p>Formula:C10H11NOSPurity:99.68%Color and Shape:SolidMolecular weight:193.275-Fluoro-2'-deoxycytidine
CAS:<p>5-Fluoro-2'-deoxycytidine (2'-DEOXY-5-FLUOROCYTIDINE) is an inhibitor of DNA methyltransferase (DNMT) .</p>Formula:C9H12FN3O4Purity:97.91%Color and Shape:Fine White PowderMolecular weight:245.21A-366
CAS:<p>A-366 is a highly selective peptide-competitive histone methyltransferase G9a inhibitor with IC50s of 3.3 and 38 nM for G9a and GLP, respectively.</p>Formula:C19H27N3O2Purity:97.28% - 99.8%Color and Shape:SolidMolecular weight:329.44UNC3866 TFA(1872382-47-2 free base)
CAS:<p>UNC3866 TFA is a potent antagonist of the CBX7-H3 interaction as determined by AlphaScreen.</p>Formula:C45H67F3N6O10Purity:98.43%Color and Shape:SolidMolecular weight:909.046-Thioguanine
CAS:<p>6-Thioguanine (2-Amino-6-purinethiol) is an antineoplastic compound which also has antimetabolite action. The drug is used in the therapy of acute leukemia.</p>Formula:C5H5N5SPurity:98.34% - >99.99%Color and Shape:Odorless Or Almost Odorless Pale Yellow Crystalline PowderMolecular weight:167.19IOX4
CAS:<p>IOX4 is a potent PHD2 inhibitor (IC50 = 1.6 nM)</p>Formula:C15H16N6O3Purity:99.97%Color and Shape:SolidMolecular weight:328.33NEO2734
CAS:<p>NEO2734 (EP31670) is an orally active and selective inhibitor of p300/CBP and BET bromodomain(IC50 of <30 nM for both p300/CBP and BET bromodomains).</p>Formula:C22H24F3N3O3Purity:98.72% - 98.8%Color and Shape:SolidMolecular weight:435.44GSK343
CAS:<p>GSK343, a specific and effective EZH2 inhibitor (IC50=4 nM), exhibits 60 fold specificity activity against EZH1, and >1000 fold specificity activity against</p>Formula:C31H39N7O2Purity:98% - 99.9%Color and Shape:SolidMolecular weight:541.69Panaxadiol
CAS:<p>Panaxadiol (20(R)-Panaxadiol) is a novel antitumor agent extracted from the Chinese medical herb Panax ginseng.</p>Formula:C30H52O3Purity:98% - 99.9%Color and Shape:SolidMolecular weight:460.73XL228
CAS:<p>XL228 is an inhibitor of multi-targeted tyrosine kinase (IC50s: 5, 3.1, 1.6, 6.1, 2 nM for Bcr-Abl, Aurora A, IGF-1R, Src, and Lyn, respectively).</p>Formula:C22H31N9OPurity:99.07%Color and Shape:SolidMolecular weight:437.54Tozasertib
CAS:<p>Tozasertib (MK-0457) is a pan-Aurora kinase inhibitor (Kis: 0.6/18/4.6 nM for Aurora A/Aurora B/Aurora C).</p>Formula:C23H28N8OSPurity:99.99%Color and Shape:SolidMolecular weight:464.591-benzyl-2-ethyl-4,5,6,7-tetrahydro-1H-indol-4-one
CAS:<p>1-benzyl-2-ethyl-4,5,6,7-tetrahydro-1H-indol-4-one is an inhibitor Bromodomain-containing protein 4 (human).</p>Formula:C17H19NOPurity:99.08%Color and Shape:SolidMolecular weight:253.34GSK620
CAS:<p>GSK620, a selective pan-BD2 inhibitor, has anti-inflammatory properties and favorable oral pharmacokinetics.</p>Formula:C18H19N3O3Purity:99.42% - 99.88%Color and Shape:SolidMolecular weight:325.36Talazoparib
CAS:<p>Talazoparib (LT-673) is a new-type PARP inhibitor (IC50: 0.58 nM), It similarly binds to PARP1/2 (Kis: 1.2/0.85 nM).</p>Formula:C19H14F2N6OPurity:97.02% - 99.92%Color and Shape:SolidMolecular weight:380.35Solcitinib
CAS:<p>Solcitinib (GLPG-0778), a JAK1 inhibitor, may treat psoriasis, ulcerative colitis, and lupus.</p>Formula:C22H23N5O2Purity:99.61% - 99.82%Color and Shape:SolidMolecular weight:389.45Dbet57
CAS:<p>dBET57: PROTAC-based BRD4BD1 degrader, DC50/5h at 500 nM, ineffective on BRD4BD2.</p>Formula:C34H31ClN8O5SPurity:99.36% - 99.52%Color and Shape:SolidMolecular weight:699.18MAT2A inhibitor 4
CAS:<p>MAT2A Inhibitor 4 acts as an inhibitor targeting the catalytic subunit of methionine S-adenosyltransferase-2 (MAT2A), offering potential utility in cancer</p>Formula:C16H15ClFNPurity:99.17%Color and Shape:SolidMolecular weight:275.75Mivebresib
CAS:<p>Mivebresib (ABBV-075) is a potent BET inhibitor with antitumor effects, disrupting gene expression and MYC, TMPRSS2-ETS proteins.</p>Formula:C22H19F2N3O4SPurity:98.74% - 99.32%Color and Shape:SolidMolecular weight:459.47PHA-680632
CAS:<p>PHA-680632 is potent inhibitor of Aurora A, Aurora B and Aurora C with IC50 of 27 nM, 135 nM and 120 nM, respectively.</p>Formula:C28H35N7O2Purity:98.2%Color and Shape:SolidMolecular weight:501.623-Aminobenzamide
CAS:<p>3-Aminobenzamide (PARP-IN-1) is an effective inhibitor of PARP (IC50<50 nM in CHO cells) and a mediator of oxidant-induced myocyte dysfunction during</p>Formula:C7H8N2OPurity:98.4% - 99.5%Color and Shape:White To Off-White PowderMolecular weight:136.15SF2523
CAS:<p>SF2523 is a highly selective and potent inhibitor.</p>Formula:C19H17NO5SPurity:99.1% - 99.51%Color and Shape:SolidMolecular weight:371.41JNJ-64619178
CAS:<p>JNJ-64619178: selective, oral, pseudo-irreversible PRMT5 inhibitor (IC50: 0.14 nM), effective in lung cancer.</p>Formula:C22H23BrN6O2Purity:98.44% - 99.63%Color and Shape:SolidMolecular weight:483.36GeA-69
CAS:<p>GeA-69 (GeA69) is a selective and allosteric PARP14 macrodomain 2 (MD2) inhibitor (Kd: 0.86 μM in ITC assays).</p>Formula:C20H16N2OPurity:99.85%Color and Shape:SolidMolecular weight:300.35TTK21
CAS:<p>TTK21 is an activator of CBP/p300 histone acetyltransferase activity.</p>Formula:C17H15ClF3NO2Purity:98.43%Color and Shape:SolidMolecular weight:357.75PX-478
CAS:<p>PX-478 is a HIF-1α inhibitor with selectivity, oral activity, and blood-brain barrier permeability.</p>Formula:C13H20Cl4N2O3Purity:97% - 99.79%Color and Shape:SolidMolecular weight:394.12LW6
CAS:<p>LW6 (HIF-1α inhibitor) is a novel HIF-1 inhibitor.</p>Formula:C26H29NO5Purity:98.1% - 98.22%Color and Shape:SolidMolecular weight:435.51Dehydrocorydaline
CAS:<p>1.</p>Formula:C22H24NO4Purity:99.84%Color and Shape:SolidMolecular weight:366.43Belzutifan
CAS:<p>"Belzutifan (MK-6482) is an oral HIF-2α inhibitor for ccRCC, with enhanced potency (IC50: 9 nM)."</p>Formula:C17H12F3NO4SPurity:99.34% - 99.88%Color and Shape:SolidMolecular weight:383.34I-BET151
CAS:<p>I-BET151 (GSK1210151A) (GSK1210151A) is a specific BET inhibitor for BRD2/3/4 (IC50: 0.5/0.25/0.79 μM, in cell-free assays).</p>Formula:C23H21N5O3Purity:97.34% - 99.63%Color and Shape:SolidMolecular weight:415.44Veliparib
CAS:<p>Veliparib (ABT-888) (ABT-888) is an orally bioavailable inhibitor of PARP (Kis: 5.2/2.9 nM for PARP1/2). It enhances apoptosis and autophagy.</p>Formula:C13H16N4OPurity:98.66% - 99%Color and Shape:SolidMolecular weight:244.29Tranylcypromine hemisulfate
CAS:<p>Tranylcypromine hemisulfate (Tranylcypromine Sulfate) is an inhibitor of monoamine oxidase (MAO) and lysine-specific demethylase 1 (LSD1) with a rapid onset of</p>Formula:C9H11N1H2SO4Purity:98% - 99.96%Color and Shape:SolidMolecular weight:182.23SGI-1027
CAS:<p>SGI-1027 (DNA Methyltransferase Inhibitor II) is an effective and selective inhibitor of DNA methyltransferase (DNMT).</p>Formula:C27H23N7OPurity:99.45% - 99.78%Color and Shape:SolidMolecular weight:461.52GSK467
CAS:<p>GSK467 is a potent and selective inhibitor of KDM5 (JARID1)(Ki : 10 nM).</p>Formula:C17H13N5O2Purity:99.55%Color and Shape:SolidMolecular weight:319.32MG 149
CAS:<p>MG 149 (Tip60 HAT inhibitor) is a selective and potent Tip60 inhibitor with IC50 of 74 uM, similar potentcy for MOF(IC50= 47 uM).</p>Formula:C22H28O3Purity:98.69% - 99.86%Color and Shape:SolidMolecular weight:340.46UNC3866
CAS:<p>UNC3866 is a potent antagonist of the CBX7-H3 interaction as determined by AlphaScreen.</p>Formula:C43H66N6O8Purity:88.06% - 99.62%Color and Shape:SolidMolecular weight:795.02GW779439X
CAS:<p>GW779439X is an inhibitor of CDK.</p>Formula:C22H21F3N8Purity:97.87%Color and Shape:SolidMolecular weight:454.45CCT241736
CAS:<p>CCT241736 is an orally bioavailable dual FLT3/Aurora kinase inhibitor that also inhibits clinically relevant FLT3-resistant mutants including FLT3-ITD and FLT3</p>Formula:C22H23Cl2N7Purity:96.2% - 99.81%Color and Shape:SolidMolecular weight:456.37G244-LM
CAS:<p>G244-LM is a potent and specific inhibitor of tankyrase 1/2. G244-LM inhibits Wnt signaling.</p>Formula:C18H22N4O3S2Purity:98.46%Color and Shape:SolidMolecular weight:406.52AMG 900
CAS:<p>AMG 900 is a potent and highly selective pan-Aurora kinases inhibitor for Aurora A/B/C with IC50 of 5 nM/4 nM /1 nM.</p>Formula:C28H21N7OSPurity:98.4% - 99.51%Color and Shape:SolidMolecular weight:503.583-Methoxybenzamide
CAS:<p>3-Methoxybenzamide (3-MBA) is a competitive inhibitor of poly(ADP-ribose) synthetase.</p>Formula:C8H9NO2Purity:98.52%Color and Shape:SolidMolecular weight:151.16Amifostine trihydrate
CAS:<p>Amifostine trihydrate (WR2721) is the first approved radioprotective drug, used to decrease the risk of kidney problems caused by treatment with cisplatin.</p>Formula:C5H15N2O3PS·3H2OPurity:99.71% - 99.80%Color and Shape:SolidMolecular weight:268.27Fosifidancitinib
CAS:<p>Fosifidancitinib is a potent inhibitor of JAK 1 and JAK 3.</p>Formula:C21H21FN5O7PPurity:99.54%Color and Shape:SolidMolecular weight:505.39ARV-771
CAS:<p>ARV-771 is an effective BET degrader based on PROTAC technology.Cost-effective and quality-assured.</p>Formula:C49H60ClN9O7S2Purity:99.69%Color and Shape:SolidMolecular weight:986.64Oclacitinib maleate
CAS:<p>Oclacitinib maleate is a selective JAK inhibitor (IC50: 10-99 nM; JAK1 cytokines: 36-249 nM), with no effect on 38 non-JAK kinases.</p>Formula:C15H23N5O2S·C4H4O4Purity:99.17%Color and Shape:SolidMolecular weight:453.51CPI-169 racemate
CAS:<p>CPI-169 racemate (CPI 169) is a potent, and selective EZH2 inhibitor with IC50 of 0.24 nM, 0.51 nM, and 6.1 nM for EZH2 WT, EZH2 Y641N, and EZH1, respectively.</p>Formula:C27H36N4O5SPurity:99.59%Color and Shape:SolidMolecular weight:528.66BET bromodomain inhibitor
CAS:<p>BET bromodomain inhibitor is a potent BET inhibitor.</p>Formula:C24H20ClN5O2Purity:98.22% - 99.85%Color and Shape:SolidMolecular weight:445.9BIX-01294 trihydrochloride
CAS:<p>BIX-01294 trihydrochloride is an inhibitor of G9a histone methyltransferase.In a cell-free assay, the IC50=2.7 μM for G9a histone methyltransferase.</p>Formula:C28H38N6O2·3HClPurity:99.41% - 99.95%Color and Shape:SolidMolecular weight:600.02ENMD-2076
CAS:<p>ENMD-2076, a multi-targeted kinase inhibitor, has specific activity against Aurora A, Flt3, KDR/VEGFR2, Flt4/VEGFR3, FGFR1, FGFR2, Src, PDGFRα.</p>Formula:C21H25N7Purity:97.63% - ≥95%Color and Shape:SolidMolecular weight:375.47
