p38 MAPK
p38 MAPKs are a subgroup of MAPKs that respond to stress signals and are involved in the regulation of inflammation, cell differentiation, apoptosis, and autophagy. p38 MAPK signaling is crucial in immune responses and is implicated in various diseases, including chronic inflammatory conditions, cancer, and neurodegenerative disorders. At CymitQuimica, we provide a comprehensive range of p38 MAPK inhibitors and modulators to support your research in inflammation, stress response, and therapeutic development.
Found 117 products of "p38 MAPK"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Dihydrocaffeic acid
CAS:<p>Dihydrocaffeic acid, a chlorogenic acid metabolite, has antioxidant, anti-Alzheimer's, neuroprotective, and lipid-lowering properties.</p>Formula:C9H10O4Purity:98.63%Color and Shape:SolidMolecular weight:182.17Aspirin
CAS:<p>Aspirin (Acetylsalicylic Acid) is a COX inhibitor. Aspirin has anti-inflammatory, antipyretic and analgesic activities. Cost-effective and quality-assured.</p>Formula:C9H8O4Purity:99.78% - 99.91%Color and Shape:White Solid CrystallineMolecular weight:180.16PF-3644022
CAS:<p>PF-3644022 is a selective MK2 inhibitor, effective against TNFα (IC50: 5.2 nM, Ki: 3 nM), with anti-inflammatory properties. Also blocks MK3 and PRAK.</p>Formula:C21H18N4OSPurity:98.13%Color and Shape:SolidMolecular weight:374.46Hesperetin
CAS:<p>Hesperetin belongs to the flavanone class of flavonoids.</p>Formula:C16H14O6Purity:98.45% - 99.27%Color and Shape:SolidMolecular weight:302.28Oxidopamine hydrochloride
CAS:<p>Oxidopamine hydrochloride (6-Hydroxydopamine hydrochloride) is an neurotransmitter dopamine antagonist.</p>Formula:C8H12ClNO3Purity:98.34% - 99.85%Color and Shape:Physical Description Beige Solid (Ntp 1992)Molecular weight:205.64LXH254
CAS:<p>LXH254 is a B/C RAF inhibitor with IC50 values of 0.2 nM and 0.07 nM for inhibiting BRAF and CRAF.Cost-effective and quality-assured.</p>Formula:C25H25F3N4O4Purity:98.3% - 99.92%Color and Shape:SolidMolecular weight:502.49Carbimazole
CAS:<p>Carbimazole, an imidazolium-based thyroid blocker, turns to MMI in the body. Used in Graves' disease research.</p>Formula:C7H10N2O2SPurity:99.98%Color and Shape:SolidMolecular weight:186.23AZD7624
CAS:<p>AZD7624 is an p38 inhibitor. It has potent anti-inflammatory activity.</p>Formula:C27H30FN5O3Purity:98.82%Color and Shape:SolidMolecular weight:491.56Oxidopamine hydrobromide
CAS:<p>Oxidopamine hydrobromide (6-OHDA hydrobromide) is a neurotransmitter dopamine antagonist.</p>Formula:C8H12BrNO3Purity:98.22% - 99.88%Color and Shape:Beige To Brown Fine Crystalline PowderMolecular weight:250.09Dilmapimod
CAS:<p>Dilmapimod (SB-681323) is a potent inhibitor of p38 MAPK ,it potentially suppresses inflammation in chronic obstructive pulmonary disease.</p>Formula:C23H19F3N4O3Purity:97.53%Color and Shape:SolidMolecular weight:456.42Dehydrocorydaline chloride
CAS:<p>Dehydrocorydaline chloride (13-Methylpalmatine chloride) is an alkaloid with anti-inflammatory and anti-cancer activity. Can improve the activation of p38 MAPK.</p>Formula:C22H24ClNO4Purity:99.53%Color and Shape:SolidMolecular weight:401.88BI-3406
CAS:<p>BI-3406 is an orally active, highly potent and selective between KRAS and Son of Sevenless 1 (SOS1) interaction inhibitor(IC50 : 6 nM),with anticancer activity.</p>Formula:C23H25F3N4O3Purity:99.2% - 99.66%Color and Shape:SolidMolecular weight:462.46SB220025
CAS:<p>SB220025 is a P38 mitogen-activated protein kinase inhibitor that inhibits p56Lck and PKC, and inhibits angiogenesis.</p>Formula:C18H19FN6Purity:99.44%Color and Shape:SolidMolecular weight:338.38p38α inhibitor 3
CAS:<p>p38α inhibitor 3 is a inhibitor of the mitogen-activated protein kinase p38α that can block the effectiveness of myoblast differentiation.</p>Formula:C19H20FNOPurity:99.94%Color and Shape:SoildMolecular weight:297.37p38 MAP Kinase Inhibitor Ⅵ
CAS:<p>p38 MAP Kinase Inhibitor Ⅵ is a potent p38 MAP Kinase inhibitor with anti-inflammatory activity.</p>Formula:C16H13FN2OS2Purity:98.53%Color and Shape:SolidMolecular weight:332.42p38α inhibitor 5
CAS:<p>The compound p38α inhibitor5 (compound 1) is a PROTAC-type ligand that targets p38 and is utilized in the synthesis of NR-11c.</p>Formula:C26H23BrF2N2O3Color and Shape:SolidMolecular weight:529.37WYE-687
CAS:<p>WYE-687 is a selective mTOR inhibitor (IC50: 7 nM), over 100x more selective for mTOR than PI3Kα/γ, affecting mTORC1/pS6K and mTORC2/P-AKT(S473).</p>Formula:C28H32N8O3Purity:99.93%Color and Shape:SolidMolecular weight:528.61Z16078526
CAS:<p>Z16078526 promotes Ucp1, p38 MAPK, lipolysis, thermogenic genes, and mitochondrial activity in mouse brown adipocytes.</p>Formula:C18H17N3O4SPurity:98.93%Color and Shape:SolidMolecular weight:371.41Talmapimod hydrochloride
CAS:<p>Talmapimod hydrochloride: selective p38α inhibitor, 9 nM IC50, 10x less effective on p38β, >2000-fold selective vs 20+ kinases.</p>Formula:C27H31Cl2FN4O3Purity:98%Color and Shape:SolidMolecular weight:549.46PDE4-IN-26
<p>PDE4-IN-26 (Compound A5) is an orally active, highly selective inhibitor of PDE4. It exhibits anti-inflammatory properties by inhibiting p38 MAPK phosphorylation. In mouse models of acute lung injury and chronic obstructive pulmonary disease, PDE4-IN-26 reduces lung inflammation, damage, and fibrosis, while promoting sputum secretion and alleviating cough. It is useful for researching lung injury-related diseases.</p>Formula:C22H18F2N4O3SColor and Shape:SolidMolecular weight:456.47Ro-3201195
CAS:<p>Ro-3201195 is a novel orally available p38 MAPK inhibitor with high selectivity.</p>Formula:C19H18FN3O4Purity:99.15%Color and Shape:SolidMolecular weight:371.36Cyclotraxin B
CAS:<p>TrkB receptor antagonist; inhibits BDNF-TrkB signaling (IC50 = 0.30 nM); alters receptor shape; may reduce anxiety in mice.</p>Formula:C48H73N13O17S3Purity:98%Color and Shape:SolidMolecular weight:1200.36Esculin sesquihydrate
CAS:<p>Esculin sesquihydrate, a coumarin glucoside with fluorescent properties and a constituent of ash bark, improves cognitive deficits associated with experimental</p>Formula:C15H16O9H2OPurity:98%Color and Shape:SolidMolecular weight:367.31MAP3K5-IN-1
CAS:<p>Compound 7, also known as 3′-O-Demethyl-4′-N-demethyl-4′-N-acetyl-4′-epi-staurosporine, serves as an inhibitor of protein kinases, displaying IC50 values of 0.092 μM for PKC-α, 0.26 μM for ROCK, and 0.77 μM for ASK1. Additionally, this compound exhibits significant cytotoxicity towards PC-3 cancer cells, with an IC50 of 0.16 μM [1].</p>Formula:C28H24N4O4Color and Shape:SolidMolecular weight:480.51DB-10
<p>DB-10 serves as a precursor to 3-nbutylphthalide (NBP). It is absorbed by cells in a temperature and energy-dependent manner through the pyrilamine cation transporter. DB-10 enhances cell survival and rapidly converts into an active form in vivo, increasing accumulation within the brain. This compound is applicable in ischemic stroke research.</p>Color and Shape:Odour SolidOVA-E1 peptide TFA
CAS:<p>OVA-E1 peptide TFA activates the p38 and JNK cascades similarly in mutant and wild-type thymocytes.</p>Formula:C49H77F3N10O16Purity:98%Color and Shape:SolidMolecular weight:1119.19R1487 Hydrochloride
CAS:<p>R1487 Hydrochloride (R1487 (Hydrochloride)) is an orally bioavailable and highly selective inhibitors of p38α.</p>Formula:C19H19ClF2N4O3Purity:99.42%Color and Shape:SolidMolecular weight:424.83Kaempferol-3-O-glucorhamnoside
CAS:<p>Kaempferol-3-O-glucorhamnoside (Kaempferol 3-glucorhamnoside), a flavonoid derived from plant Thesium chinense Turcz, inhibits inflammatory responses via MAPK</p>Formula:C27H30O15Purity:96.96% - 98.17%Color and Shape:SolidMolecular weight:594.5Neflamapimod
CAS:<p>Neflamapimod (VX-745) , a specific and effective inhibitor of p38α(IC50=10 nM), is 22-fold greater specificity against p38β and no inhibition activity to p38γ.</p>Formula:C19H9Cl2F2N3OSPurity:97.88% - 99.75%Color and Shape:SolidMolecular weight:436.26Sertaconazole nitrate
CAS:<p>Sertaconazole nitrate, a broad-spectrum topical antifungal, treats skin and mucosal infections.</p>Formula:C20H15Cl3N2OS·HNO3Purity:98.66% - 99.65%Color and Shape:SolidMolecular weight:500.78ASK1-IN-1
CAS:<p>ASK1-IN-1 inhibits apoptosis kinase 1, crucial in cell stress responses, with 21 nM IC50.</p>Formula:C19H19N9O2Purity:99.92%Color and Shape:SolidMolecular weight:405.41SB 202190
CAS:<p>SB 202190 (FHPI) is a p38 MAPK inhibitor that inhibits p38α and p38β2 (IC50=50/100 nM) selectively and cell-permeably.</p>Formula:C20H14FN3OPurity:98% - 99.84%Color and Shape:Pale YellowMolecular weight:331.34CK1-IN-1
CAS:<p>CK1-IN-1, a CK1 inhibitor with IC50: 15nM CK1δ, 16nM CK1ε, 73nM p38σ; patent WO2015119579A1.</p>Formula:C24H15F2N3Purity:98.79%Color and Shape:SolidMolecular weight:383.39Gypenoside L
CAS:<p>Gypenoside L inhibits autophagic flux and induces cell death in human esophageal cancer cells through endoplasm reticulum stress-mediated Ca2+ release.</p>Formula:C42H72O14Purity:99.42% - 99.65%Color and Shape:SolidMolecular weight:801.01UM-164
CAS:<p>UM-164 (DAS-DFGO-II), a highly potent c-Src inhibitor with a dissociation constant (Kd) of 2.7 nM, also effectively inhibits p38α and p38β.</p>Formula:C30H31F3N8O3SPurity:98.72% - 99.52%Color and Shape:SolidMolecular weight:640.68Adezmapimod
CAS:<p>Adezmapimod (SB 203580) is a p38 MAPK inhibitor (IC50=0.3-0.5 μM) that is selective and ATP-competitive.</p>Formula:C21H16FN3OSPurity:99.42% - 99.93%Color and Shape:White SolidMolecular weight:377.435,6,7-TRIMETHOXYFLAVONE
CAS:<p>5,6,7-Trimethoxyflavone, a natural product extracted from Japanese Callicarpa, acts as a p38-α MAPK inhibitor and exhibits anti-inflammatory properties.</p>Formula:C18H16O5Purity:99.05% - 99.49%Color and Shape:SolidMolecular weight:312.32SD 0006
CAS:<p>SD 0006 (SD-06) is a MAPK p38 alpha inhibitor( IC50 : 110 nM) for the treatment of arthritis.</p>Formula:C20H20ClN5O2Purity:98.32%Color and Shape:SolidMolecular weight:397.86Nitidine chloride
CAS:<p>1.</p>Formula:C21H18ClNO4Purity:96.59% - 98.91%Color and Shape:SolidMolecular weight:383.82SB 239063
CAS:<p>SB 239063 (SB239063) is a potent and selective p38 MAPKα/β inhibitor with IC50 of 44 nM, showing no activity against the γ- and δ-kinase isoforms.</p>Formula:C20H21FN4O2Purity:99.42% - 99.81%Color and Shape:SolidMolecular weight:368.4Rotundic acid
CAS:<p>Rotundic acid fights various cancers: HepG2, A375, NCI-H446, MCF-7, and HT-29.</p>Formula:C30H48O5Purity:96.91% - 99.97%Color and Shape:SolidMolecular weight:488.7Cornuside
CAS:<p>Cornuside boosts immunity, reduces inflammation, protects heart and liver, and guards against brain injury by modulating stress responses.</p>Formula:C24H30O14Purity:99.86% - >99.99%Color and Shape:SolidMolecular weight:542.49Andrograpanin
CAS:<p>Andrograpanin (19-HYDROXY-8(17),13-LABDADIEN-16,15-OLIDE) is a bioactive compound from Andrographis paniculata.</p>Formula:C20H30O3Purity:99.03% - 99.457%Color and Shape:SolidMolecular weight:318.45FERULIC ACID METHYL ESTER
CAS:<p>FERULIC ACID METHYL ESTER (Methyl ferulate) is a hydroxycinnamic acid that is abundant in plants. FERULIC ACID METHYL ESTER has antioxidant activities.</p>Formula:C11H12O4Purity:99.66% - 99.95%Color and Shape:SolidMolecular weight:208.21BMS-582949 hydrochloride
CAS:<p>The BMS-582949 hydrochloride (BMS-582949 HCl) is a highly specific p38α MAPK inhibitor (IC50: 13 nM).</p>Formula:C22H27ClN6O2Purity:97.57% - 98.75%Color and Shape:SolidMolecular weight:442.95R1487
CAS:<p>R1487 is an orally bioavailable and highly selective p38α mitogen-activated protein kinase inhibitor.</p>Formula:C19H18F2N4O3Purity:99.77%Color and Shape:SolidMolecular weight:388.37SR-318
CAS:<p>SR-318 inhibits TNF-α (IC50=283 nM), selectively targets p38 MAPK: IC50 of 5nM (p38α), 32nM (p38β), 6.11μM (p38α/β).</p>Formula:C27H33N5O2Purity:99.74%Color and Shape:SolidMolecular weight:459.58Afatinib Dimaleate
CAS:<p>Afatinib Dimaleate (BIBW 2992MA2) is an orally bioavailable anilino-quinazoline derivative and inhibitor of the EGFR family, with antineoplastic activity.</p>Formula:C32H33ClFN5O11Purity:98.11% - 99.87%Color and Shape:SolidMolecular weight:718.08TA-02
CAS:<p>TA-02 is a p38 MAPK inhibitor with IC50 of 20 nM.TA-02 especially inhibits TGFBR-2.</p>Formula:C20H13F2N3Purity:99.35% - 99.79%Color and Shape:SolidMolecular weight:333.33TA-01
CAS:<p>TA-01 is a potent CK1 and p38 MAPK inhibitor, with IC50s of 6.4 nM, 6.8 nM, 6.7 nM for CK1ε, CK1δ and p38 MAPK, respectively.</p>Formula:C20H12F3N3Purity:99.55% - 99.94%Color and Shape:SolidMolecular weight:351.32Ralimetinib dimesylate
CAS:<p>Ralimetinib dimesylate (LY2228820 dimesylate) is a orally available, p38 MAPK inhibitor with potential anti-inflammatory and antineoplastic activities.</p>Formula:C24H29FN6·2CH4O3SPurity:98% - 99.38%Color and Shape:SolidMolecular weight:612.74Skepinone-L
CAS:<p>Skepinone-L (CBS3830) is a selective p38 mitogen-activated protein kinase inhibitor.</p>Formula:C24H21F2NO4Purity:99.56% - >99.99%Color and Shape:SolidMolecular weight:425.42SKF-86002
CAS:<p>SKF-86002 is an effective inhibitor of p38 MAP kinase (IC50: 0.5-1 uM); inhibits LPS-induced IL-1 and TNF-α production in human monocytes (IC50: 1 μM).</p>Formula:C16H12FN3SPurity:98% - 99.85%Color and Shape:SolidMolecular weight:297.35SB 242235
CAS:<p>SB 242235 is a potent and selective p38 MAP kinase inhibitor that may be an effective therapy for cytokine-mediated diseases.</p>Formula:C19H20FN5OPurity:99.13% - 99.68%Color and Shape:SolidMolecular weight:353.39Rhoifolin
CAS:<p>Rhoifolin (Apigenin 7-O-neohesperidoside) is extracted from Turpinia arguya Seem dried leaves.</p>Formula:C27H30O14Purity:98.11% - 98.58%Color and Shape:SolidMolecular weight:578.52TAK-715
CAS:<p>TAK-715 is a p38 MAPK inhibitor for p38α.</p>Formula:C24H21N3OSPurity:99.83%Color and Shape:SolidMolecular weight:399.51PD 169316
CAS:<p>PD 169316 is a potent, cell-permeable and selective p38 MAP kinase inhibitor.</p>Formula:C20H13FN4O2Purity:98.65%Color and Shape:SolidMolecular weight:360.34AMG-47a
CAS:<p>AMG-47a inhibits Lck, T cell growth, and degrades KRAS oncoprotein, affecting EGFP-KRASG12V but not EGFP.</p>Formula:C29H28F3N5O2Purity:98%Color and Shape:SolidMolecular weight:535.56Acumapimod
CAS:<p>Acumapimod (BCT-197) is an orally active inhibitor of p38α MAPK (IC50 <1 μM).</p>Formula:C22H19N5O2Purity:≥95%Color and Shape:SolidMolecular weight:385.42Skatole
CAS:<p>Skatole (3-Methyl-1H-indole), produced by bacteria, regulates intestinal epithelial cellular functions through activating aryl hydrocarbon receptors and p38.</p>Formula:C9H9NPurity:99.74%Color and Shape:Leaves From Petroleum Ether; White-Brown Scales SolidMolecular weight:131.17MW-150
CAS:<p>MW-150 (MW01-18-150SRM) is a unique protein kinase inhibitor, is a selective, CNS penetrant, and orally active inhibitor of p38α MAPK with a Ki of 101 nM.</p>Formula:C24H23N5Purity:97.35% - 99.27%Color and Shape:SolidMolecular weight:381.47Isoliquiritin apioside
CAS:<p>Isoliquiritin apioside, from Glycyrrhizae radix, inhibits MMP9, MAPK, NF-κB, reduces cancer cell invasion, angiogenesis, and fights oxidative DNA damage.</p>Formula:C26H30O13Purity:98.84% - 99.27%Color and Shape:SolidMolecular weight:550.51Esculin
CAS:<p>Esculin (Aesculin) is a glucoside found in horse chestnuts.</p>Formula:C15H16O9Purity:97.93% - 99.83%Color and Shape:Cream PowderMolecular weight:340.28Doramapimod
CAS:<p>Doramapimod (BIRB 796) is a highly potent inhibitor of p38 MAPK (Kd: 0.1 nM), but weakly inhibits c-RAF, Fyn, Lck, ERK-1, SYK, IKK2, and ZAP-70.</p>Formula:C31H37N5O3Purity:97.14% - 98.80%Color and Shape:SolidMolecular weight:527.66Bakuchiol
CAS:<p>Bakuchiol: anti-tumor, anti-helminthic, DNA polymerase1 inhibitor, cytotoxic, and anti-bacterial, may prevent dental caries.</p>Formula:C18H24OPurity:98.04% - 99.05%Color and Shape:Brownish Yellow Liquid ViscousMolecular weight:256.38PH-797804
CAS:<p>PH-797804 is a pyridinone inhibitor of p38α (IC50: 26 nM, in a cell-free assay); 4-fold more selective versus p38β and does not inhibit JNK2.</p>Formula:C22H19BrF2N2O3Purity:97.90% - 98.27%Color and Shape:SolidMolecular weight:477.3Dehydrocorydaline
CAS:<p>1.</p>Formula:C22H24NO4Purity:99.84%Color and Shape:SolidMolecular weight:366.43Bisabolangelone
CAS:<p>Bisabolangelone: anti-tumor, anti-inflammatory, anti-microbial, antioxidant, blocks MAPK/NF-κB in dendritic cells.</p>Formula:C15H20O3Purity:98.91%Color and Shape:SolidMolecular weight:248.32SM-7368
CAS:<p>The NF-κB Activation Inhibitor III, controls the biological activity of NF-κB. It is primarily used for Inflammation/Immunology applications.</p>Formula:C10H5ClN4O5SPurity:99.64%Color and Shape:SolidMolecular weight:328.69AMG 900
CAS:<p>AMG 900 is a potent and highly selective pan-Aurora kinases inhibitor for Aurora A/B/C with IC50 of 5 nM/4 nM /1 nM.</p>Formula:C28H21N7OSPurity:98.4% - 99.51%Color and Shape:SolidMolecular weight:503.58SD-169
CAS:<p>SD-169 (SD 169) is a selective and ATP competitive the MAP kinases p38α and p38β inhibitor.</p>Formula:C9H8N2OPurity:98.6%Color and Shape:SolidMolecular weight:160.17Afatinib
CAS:<p>Afatinib (BIBW 2992) is an irreversible and orally EGFR family inhibitor that inhibits EGFR and HER2. Afatinib has antitumor activity. Cost effective and quality assured.</p>Formula:C24H25ClFN5O3Purity:98.56% - 99.9%Color and Shape:Off-White SolidMolecular weight:485.94N-Feruloyloctopamine
CAS:<p>N-Feruloyloctopamine is a natural product.</p>Formula:C18H19NO5Purity:99.70%Color and Shape:SolidMolecular weight:329.35Sesamolin
CAS:<p>Sesamolin and sesamin guard nerves, reduce microglia damage by blocking p38 MAPK and caspase-3, and curb nitric oxide in stimulated cells.</p>Formula:C20H18O7Purity:98.77% - 99.04%Color and Shape:SolidMolecular weight:370.35Pamapimod
CAS:<p>Pamapimod (R1503) (R-1503, Ro4402257) is a novel, selective inhibitor of p38 mitogen-activated protein kinase.</p>Formula:C19H20F2N4O4Purity:99.52% - 99.99%Color and Shape:SolidMolecular weight:406.38Losmapimod
CAS:<p>Losmapimod (GSK-AHAB) (GW856553X; SB856553; GSK-AHAB) is a specific, potent, and orally active p38 MAPK inhibitor (pKi: 8.1/7.6 for p38α/β).</p>Formula:C22H26FN3O2Purity:98.35% - 99.89%Color and Shape:SolidMolecular weight:383.46RWJ-67657
CAS:<p>RWJ-67657 is a selective oral p38α/β MAPK inhibitor with IC50s of 1/11μM; inactive on p38γ/δ with cardioprotection.</p>Formula:C27H24FN3OPurity:99.66%Color and Shape:SolidMolecular weight:425.5Sertaconazole
CAS:<p>Sertaconazole is a broad-spectrum antifungal.</p>Formula:C20H15Cl3N2OSPurity:99.483%Color and Shape:SolidMolecular weight:437.77Paris saponin VII
CAS:<p>Paris saponin VII (Dioscini) shows inhibitory effects on cell proliferation.</p>Formula:C51H82O21Purity:99.51% - 99.63%Color and Shape:SolidMolecular weight:1031.18Talmapimod
CAS:<p>Talmapimod (SCIO-469): Oral ATP-competitive p38α inhibitor, IC50 = 9 nM (p38α), 90 nM (p38β), >2000-fold selectivity over 20 kinases.</p>Formula:C27H30ClFN4O3Purity:98% - 99.9%Color and Shape:SolidMolecular weight:513BMS582949
CAS:<p>BMS-582949 inhibits p38 MAPK with 13 nM IC50, blocking kinase activity and activation.</p>Formula:C22H26N6O2Purity:98.11%Color and Shape:SolidMolecular weight:406.48Pexmetinib
CAS:<p>Pexmetinib (ARRY-614) is an orally bioavailable dual p38 MAPK/Tie-2 inhibitor.Cost-effective and quality-assured.</p>Formula:C31H33FN6O3Purity:99.07% - 99.66%Color and Shape:SolidMolecular weight:556.63Dehydrocorydaline nitrate
CAS:<p>DHC curbs antibody and cell-mediated allergies, inhibits mitochondrial potential in macrophages, and has antinociceptive, anti-inflammatory effects.</p>Formula:C22H24N2O7Purity:99.79% - 99.92%Color and Shape:SolidMolecular weight:428.44VX-702
CAS:<p>VX-702: selective p38α MAPK inhibitor, potent anti-cytokine for rheumatoid arthritis.</p>Formula:C19H12F4N4O2Purity:99% - >99.99%Color and Shape:SolidMolecular weight:404.32TLC1566-0618
CAS:<p>TLC1566-0618 shows antitumor activity and targets stat.</p>Formula:C20H15NO3S3Purity:98%Color and Shape:SolidMolecular weight:413.53(S)-(-)-PH-797804
CAS:Controlled ProductFormula:C19H38N5O5Color and Shape:NeatMolecular weight:416.536LY 294002 Hydrochloride
CAS:Controlled Product<p>Applications LY 294002 Hydrochloride is a highly selective inhibitor of Phosphatidylinositol 3-kinase (PI3K). It is a salt analogue of LY 294002 (L486590).<br>References Lin, C., et. al.: J. Biol. Chem., 286, 10483 (2011); Cao, H., et. al.: J. Biol. Chem., 288, 30399 (2013);<br></p>Formula:C19H17NO3·(HCl)Color and Shape:NeatMolecular weight:343.8SB 706504
CAS:<p>SB 706504 is an effective p38 MAPK inhibitor that suppresses inflammatory gene expression in macrophages and inhibits TNFα production in COPD.</p>Formula:C24H19F3N8OPurity:98.686%Color and Shape:SolidMolecular weight:492.46AL 8697
CAS:<p>AL 8697 is a selective p38α MAPK inhibitor (IC50 = 6 nM) with 14-fold selectivity over p38β (IC50 = 82 nM) and 300-fold selectivity over a panel of 91 kinases.</p>Formula:C21H21F3N4OPurity:99.55% - 99.89%Color and Shape:SolidMolecular weight:402.41PF-05381941
CAS:<p>PF-05381941 is a selective and potent dual inhibitor of TAK1 and p38α that inhibits the kinase activity of TAK1 by binding to its active site.</p>Formula:C27H26N6O2Purity:98.04%Color and Shape:SolidMolecular weight:466.53EO-1606
CAS:<p>EO-1606 is a p38MAP kinase inhibitor with anti-inflammatory activity and may be used in studies of Alzheimer;s disease and dermatitis.</p>Formula:C21H17ClFNOPurity:98.28% - 98.84%Color and Shape:SolidMolecular weight:353.82p38α inhibitor 4
CAS:<p>p38α inhibitor 4 is a selective MAPK p38α inhibitor, which is used to study diabetes, pain and chronic inflammation.</p>Formula:C14H7F6N3OPurity:99.69%Color and Shape:SolidMolecular weight:347.215UR13870
CAS:<p>UR-13870 (Org 48762-0) is a p38 MAPK inhibitor that prevents bone damage in collagen-induced arthritis in mice.</p>Formula:C24H16F2N4Purity:99.18% - >99.99%Color and Shape:SolidMolecular weight:398.41AKP-001
CAS:<p>AKP-001 is a selective inhibitor of MAPK of the p38α isoform and is used in the study of immune and digestive disorders.</p>Formula:C21H13ClF2N4O2Purity:99.50% - 99.92%Color and Shape:SolidMolecular weight:426.8p38 MAPK Inhibitor
CAS:<p>p38 MAPK inhibitor is a potent inhibitor of p38 MAP kinase (IC50 = 35 nM). It inhibits senescence induced by the oncogene RAS.</p>Formula:C20H13ClFN3OPurity:99.91%Color and Shape:SolidMolecular weight:365.79SB-747651A Dihydrochloride
CAS:<p>SB-747651A dihydrochloride, an MSK1 inhibitor (IC50=11 nM), also targets PRK2, RSK1, p70S6K, ROCK-II; potential in inflammation study.</p>Formula:C16H24Cl2N8OPurity:98.05%Color and Shape:SolidMolecular weight:415.32Org OD 02-0
CAS:<p>10-Ethenyl-19-norprogesterone (Org OD 02-0) is a selective agonist for the membrane progesterone receptor α (mPRα) with an IC50 of 33.9 nM, known to activate</p>Formula:C22H30O2Purity:98%Color and Shape:SolidMolecular weight:326.47p38-α MAPK-IN-1
CAS:<p>p38-α MAPK-IN-1 is a MAPK14 (p38-α) inhibitor with IC50 of 2300 nM and 5500 nM in EFC displacement assay and HTRF assay,respectively.</p>Formula:C27H35N5O3Purity:99.93%Color and Shape:SolidMolecular weight:477.6PLK1/p38γ-IN-1
CAS:<p>PLK1/p38γ-IN-1 (compound 14) serves as a dual inhibitor targeting both PLK1 and p38γ kinases, effectively suppressing the proliferation of human hepatocellular</p>Formula:C21H26ClN3O2Purity:98%Color and Shape:SolidMolecular weight:387.9
