Metabolism
Metabolism inhibitors are compounds that interfere with metabolic pathways, altering the production and utilization of energy within cells. These inhibitors are used to study the regulation of metabolism, the role of metabolic pathways in diseases like cancer and diabetes, and to develop new therapeutic strategies. Metabolism inhibitors can target various enzymes and processes involved in glycolysis, fatty acid oxidation, and other metabolic functions. At CymitQuimica, we offer a wide range of high-quality metabolism inhibitors to support your research in biochemistry, metabolic disorders, and drug development.
Subcategories of "Metabolism"
- AhR(42 products)
- Aminopeptidase(76 products)
- CETP(20 products)
- Carbonic Anhydrase(196 products)
- Casein Kinase(139 products)
- DHFR(30 products)
- Decarboxylase(4 products)
- Dehydrogenase(302 products)
- FAAH(64 products)
- FXR(62 products)
- Factor Xa(87 products)
- Fatty Acid Synthase(37 products)
- Ferroptosis(227 products)
- GR(3 products)
- GSNOR(3 products)
- Glucokinase(56 products)
- HIF/HIF Prolyl-Hydroxylase(146 products)
- HMG-CoA Reductase(34 products)
- Hydroxylase(36 products)
- IDO(84 products)
- LDL(7 products)
- Lipase(107 products)
- Lipid(62 products)
- Lipoxygenase(133 products)
- MAO(85 products)
- MPO(2 products)
- NAMPT(40 products)
- P450(6 products)
- PAI-1(26 products)
- PDE(170 products)
- PED(1 products)
- PKM(17 products)
- PPAR(170 products)
- Phospholipase(85 products)
- ROR(47 products)
- Retinoid Receptor(20 products)
- SGK(10 products)
- Thioredoxin(12 products)
- Transferase(30 products)
- Transporter(43 products)
- UGT(4 products)
- Xanthine Oxidase (XO) Inhibitors(9 products)
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Found 9197 products of "Metabolism"
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FR-190809
CAS:FR-190809 is a nonadrenotoxic and orally efficacious inhibitor of acyl-CoA:cholesterol O-acyltransferase (ACAT) (IC50: 45 nM).Formula:C29H34FN3O6S2Purity:98%Color and Shape:SolidMolecular weight:603.73QH536
CAS:QH536 degrades HMGCR (EC50: 0.22 μM), has anti-inflammatory properties, and avoids cholesterol buildup; useful for cardiovascular and NASH research.Formula:C33H49N3O3Color and Shape:SolidMolecular weight:535.76Prostaglandin H2
CAS:Prostaglandin H2 (PGH2), initially isolated from the incubation of arachidonic acid with ovine seminal vesicle microsomes, acts as a potent vasoconstrictor. It serves as the precursor for all 2-series prostaglandins (PGs) and thromboxanes (TXs). Moreover, as a TP receptor agonist, PGH2 irreversibly aggregates human platelets at concentrations of 50-100 ng/ml.Formula:C20H32O5Color and Shape:SolidMolecular weight:352.4711,2-Dioleoyl-3-Docosohexaenoyl-rac-glycerol
CAS:1,2-Dioleoyl-3-docosohexaenoyl-rac-glycerol, a triacylglycerol, consists of oleic acid at the sn-1 and sn-2 positions and docosahexaenoic acid at the sn-3 position. This compound has been identified in human breast milk.Formula:C61H102O6Color and Shape:SolidMolecular weight:931.46GIV3727
CAS:GIV3727, a bitter taste receptor hTAS2R antagonist, inhibits the activation of hTAS2R31 by saccharin and acesulfame potassium, effectively diminishing theFormula:C12H22O2Color and Shape:SolidMolecular weight:198.39322-O16B
CAS:"9322-O16B, an ionizable cationic lipid, facilitates the generation of lipid nanoparticles (LNPs) [1]."Formula:C41H77N3O4S4Color and Shape:SolidMolecular weight:804.33ICMT-IN-51
CAS:ICMT-IN-51 (compound 43) serves as an ICMT inhibitor with an IC50 value of 0.55 μM [1].Formula:C21H26FNOColor and Shape:SolidMolecular weight:327.44SCD1/5-IN-1
CAS:SCD1/5-IN-1 (Compound 10), a selective SCD1/5 inhibitor, is utilized in the research of neurological diseases [1].Formula:C12H10N4O3Color and Shape:SolidMolecular weight:258.237ICMT-IN-32
CAS:ICMT-IN-32 (compound 70) acts as an inhibitor of isoprenylcysteine carboxyl methyltransferase (ICMT), demonstrating an IC50 value of 0.777 µM [1].Formula:C20H25NO2Color and Shape:SolidMolecular weight:311.42CYP11A1-IN-1
CAS:CYP11A1-IN-1 (compound 30) is a selective inhibitor of the enzyme CYP11A1, displaying an IC50 ranging from 201-2000 nM.Formula:C27H34N2O5Color and Shape:SolidMolecular weight:466.57SHP2-IN-20
CAS:SHP2-IN-20 (compound 193), a potent SHP2 inhibitor, exhibits an IC50 of 3 nM, making it suitable for glioblastoma research [1].Formula:C25H24F2N6Color and Shape:SolidMolecular weight:446.5(R)-Palmitoyl-(2-methyl)ethanolamide
CAS:(R)-Palmitoyl-(2-methyl)ethanolamide (Me-PEA) acts as a competitive inhibitor against [3H]-AEA metabolism, exhibiting a K i value of 6.6 μM [1].Formula:C19H39NO2Color and Shape:SolidMolecular weight:313.526ICMT-IN-24
CAS:ICMT-IN-24 (compound 63) is an inhibitor of isoprenylcysteine carboxyl methyltransferase (ICMT), exhibiting potent activity with an IC50 value of 0.19 μM [1].Formula:C22H28ClNO2Color and Shape:SolidMolecular weight:373.9212-OAHSA
CAS:Branched fatty acid esters of hydroxy fatty acids (FAHFAs) are recently discovered lipids that play a role in the body's response to fasting and high-fat diets, with a link to insulin sensitivity. These compounds consist of a long-chain fatty acid (such as palmitoleic, palmitic, oleic, or stearic acid) bonded to a hydroxy fatty acid, both ranging in length from C-16 to C-18. Specifically, 12-OAHSA is a type of FAHFA where oleic acid is attached to the 12th carbon of hydroxy stearic acid. Within the FAHFA family, OAHSAs are particularly notable for their high concentration in the serum of AG4OX mice, a strain engineered to express the Glut4 glucose transporter predominantly in their adipose tissue, which demonstrates an enhanced glucose tolerance.Formula:C36H68O4Color and Shape:SolidMolecular weight:564.9ICMT-IN-11
CAS:ICMT-IN-11 (compound 48) serves as an ICMT inhibitor with an IC50 value of 0.031 μM [1].Formula:C22H27F2NO2Color and Shape:SolidMolecular weight:375.4512-SAHSA
CAS:Branched fatty acid esters of hydroxy fatty acids (FAHFAs) are lipids recently discovered to be modulated by dietary influences such as fasting and high-fat feeding, and they play a role in enhancing insulin sensitivity. These compounds typically feature a carbon-16 or carbon-18 fatty acid (e.g., palmitoleic, palmitic, oleic, or stearic acid) esterified to a carbon-16 or carbon-18 hydroxy fatty acid. A specific example is 12-SAHSA, which consists of stearic acid linked to 12-hydroxy stearic acid. Notably, 12-SAHSA levels are found to be moderately increased in the serum of glucose tolerant AG4OX mice, a model characterized by adipose tissue-specific overexpression of the Glut4 glucose transporter.Formula:C36H70O4Color and Shape:SolidMolecular weight:566.952MR-2-93-3
CAS:MR-2-93-3, a long-chain fatty acid, functions as a carrier for polynucleotides [1].Formula:C89H150N2O8Color and Shape:SolidMolecular weight:1376.15FABP4/5-IN-4
CAS:FABP4/5-IN-4 (compound E1) effectively inhibits FABP 4 and FABP 5, displaying IC50 values of 3.78 μM and 5.72 μM, respectively. It is significant in the management of metabolic disorders such as diabetes mellitus [1].Formula:C26H21F2NO5SColor and Shape:SolidMolecular weight:497.5111-Dehydro-2,3-Dinor Thromboxane B2
CAS:11-Dehydro-2,3-Dinor Thromboxane B2 is a metabolite of Thromboxane B2 (TXB2), formed by the oxidation of TXB2 via 11-Hydroxy Thromboxane Dehydrogenase.Formula:C18H28O6Color and Shape:SolidMolecular weight:340.41KRP-109
CAS:KRP-109, a neutrophil elastase (NE) inhibitor, acts by decreasing expression of TGF-ß Signal Related Genes.Formula:C26H30N4O7Purity:98%Color and Shape:SolidMolecular weight:510.547M-0002
CAS:M-0002, a vasopressin V2 receptor antagonist, is used potentially for the treatment of ascites.Formula:C32H29Cl2N3O3Color and Shape:SolidMolecular weight:574.5Amb123203
CAS:Amb123203 is an inhibitor of the budding of mVP40 and eVP40 VLPs that acts by blocking mVP40-795 Nedd4 protein-protein interaction.Formula:C25H27N5OSColor and Shape:SolidMolecular weight:445.587-BIA
CAS:7-BIA is a receptor-type protein tyrosine phosphatase D (PTPRD) inhibitor with anti-addictive properties and can be used in the study of neuropathic pain.Formula:C15H18O6Purity:≥98% - ≥98%Color and Shape:SolidMolecular weight:294.3Ref: TM-T10190
1mg138.00€5mg334.00€10mg580.00€25mg1,071.00€50mg1,693.00€100mg2,682.00€1mL*10mM (DMSO)358.00€OGT 2115
CAS:OGT 2115 blocks heparanase (IC50=0.4µM), cleaving heparan sulfate; antiangiogenic (IC50=1µM).Formula:C24H16BrFN2O4Purity:97.27%Color and Shape:SolidMolecular weight:495.3PDE9-IN-(S)-C33
CAS:PDE9-IN-(S)-C33: potent PDE9 inhibitor with 11 nM IC50, for CNS diseases and diabetes study.Formula:C18H20ClN5OPurity:98.75%Color and Shape:SolidMolecular weight:357.84Ref: TM-T28352
1mg37.00€5mg70.00€10mg88.00€25mg144.00€50mg207.00€100mg309.00€200mg440.00€1mL*10mM (DMSO)79.00€BI-3231
CAS:BI-3231 is a hydroxysteroid 17ß-dehydrogenase 13 HSD17B13 inhibitor that inhibits hHSD17B13 .BI-3231 can be used to study cirrhosis.Formula:C16H14F2N4O3SPurity:98.2%Color and Shape:SolidMolecular weight:380.37Ref: TM-T73446
1mg69.00€5mg147.00€10mg224.00€25mg358.00€50mg512.00€100mg707.00€200mg982.00€1mL*10mM (DMSO)164.00€Dechloro Rivaroxaban
CAS:Dechloro Rivaroxaban is a Factor Xa inhibitor that inhibits free FXa and plasminogen and fibrin-associated FXa activity in humans.Formula:C19H19N3O5SPurity:98.63%Color and Shape:SolidMolecular weight:401.44Ref: TM-T78215
5mg40.00€10mg63.00€25mg107.00€50mg170.00€100mg264.00€200mg418.00€1mL*10mM (DMSO)44.00€ML400
CAS:ML400 (CID73050863) is an allosteric inhibitor of LMPTP with an EC50 of 1μM. ML400 displays good cell-based activity and rodent pharmacokinetics.Formula:C24H29N3OPurity:99.95%Color and Shape:SolidMolecular weight:375.51Ref: TM-T25824
1mg92.00€5mg172.00€10mg281.00€25mg447.00€50mg618.00€100mg853.00€500mg1,701.00€1mL*10mM (DMSO)222.00€TP-10
CAS:TP-10 is a selective inhibitor of PDE10A against other PDEs with IC50 of 0.8 nM.Formula:C26H19F3N4OPurity:99.21%Color and Shape:SolidMolecular weight:460.45Ref: TM-T13189
1mg87.00€2mg114.00€5mg177.00€10mg264.00€25mg460.00€50mg668.00€100mg945.00€500mg1,783.00€1mL*10mM (DMSO)178.00€PXS-6302 hydrochloride
CAS:PXS-6302 hydrochloride is a potent irreversible lysine oxidase (LOX) inhibitor, inhibiting Bovine LOX, rh LOXL1, rh LOXL2, rh LOXL3, and rh LOXL4 with IC50 of 3
Formula:C10H11ClF3NO2SPurity:99.89%Color and Shape:SoildMolecular weight:301.71Varespladib methyl
CAS:Varespladib methyl (LY333013), a bioavailable prodrug of Varespladib, is a selective group II secretory phospholipase A2 inhibitor.Formula:C22H22N2O5Purity:99.42% - 99.97%Color and Shape:SolidMolecular weight:394.42Ref: TM-T17218
1mg93.00€2mg123.00€5mg200.00€10mg319.00€25mg528.00€50mg730.00€100mg999.00€200mg1,333.00€1mL*10mM (DMSO)220.00€AMG 579
CAS:AMG 579 is an efficacious and selective inhibitor of PDE10A (IC50 = 0.1 nM).Formula:C25H23N5O3Purity:99.87%Color and Shape:SolidMolecular weight:441.48Ref: TM-T14217
1mg34.00€2mg44.00€5mg70.00€10mg100.00€25mgTo inquire50mgTo inquire1mL*10mM (DMSO)78.00€NPAS3-IN-1
CAS:NPAS3-IN-1 is an NPAS3-ARNT heterodimerization inhibitor that regulates NPAS3 transcription by modulating the heterodimerization of NPAS3 with ARNT.Formula:C10H5N3O2S3Purity:99.56%Color and Shape:SolidMolecular weight:295.36PA452
CAS:PA452 is a selective antagonist of retinoic X receptor (RXR) and suppresses the effect of Retinoic acid on Th1/Th2 development.Formula:C26H37N3O3Purity:97.14%Color and Shape:SolidMolecular weight:439.59Ref: TM-T16425
1mg87.00€5mg236.00€10mg380.00€25mg622.00€50mg888.00€100mg1,215.00€1mL*10mM (DMSO)259.00€TPN171
CAS:TPN171 is potent PDE5 inhibitor with subnanomolar potency for PDE5 and good selectivity over PDE6, which has the potential for the treatment of pulmonary
Formula:C24H35N5O3Purity:>99.99%Color and Shape:SolidMolecular weight:441.57h-NTPDase-IN-2
CAS:h-NTPDase-IN-2 is a broad-spectrum NTPDase inhibitor that inhibits multiple h-NTPDas isoforms.Formula:C19H16N4SPurity:99.58%Color and Shape:SolidMolecular weight:332.42RS 8359
CAS:RS 8359 is a selective MAO-A reversible inhibitor with a 2200:1 A:B ratio, exhibiting antidepressant effects.Formula:C14H12N4OPurity:99.3%Color and Shape:SolidMolecular weight:252.27Ref: TM-T16803
1mg81.00€5mg170.00€10mg274.00€25mg550.00€50mg885.00€100mg1,415.00€1mL*10mM (DMSO)188.00€ALDH2 modulator 1
CAS:ALDH2 modulator 1 is a potent and orally active modulator of acetaldehyde dehydrogenase-2 (ALDH2), which reduces blood alcohol levels in mice.
Formula:C18H18ClFN2O3Purity:99.68%Color and Shape:SoildMolecular weight:364.8PDDC inhibitor
CAS:PDDC inhibitor (Phenyl (R)-(1-(3-(3,4-dimethoxyphenyl)-2,6-dimethylimidazo[1,2-b]pyridazin-8-yl)pyrrolidin-3-yl)carbamate) is an nSMase2 inhibitor.Formula:C27H29N5O4Purity:96.09% - 99.39%Color and Shape:SolidMolecular weight:487.55CB29
CAS:CB29 is a specific inhibitor of aldehyde dehydrogenase 3A1 (ALDH3A1).
Formula:C15H15N3O5SPurity:99.36%Color and Shape:SolidMolecular weight:349.36DGAT-1 inhibitor 2
CAS:DGAT-1 inhibitor 2: effective against obesity, targets enzyme in triglyceride synthesis for diabetes treatment.Formula:C24H28N4O3Purity:98.36%Color and Shape:SolidMolecular weight:420.5Ref: TM-T11016
1mg62.00€5mg133.00€10mg205.00€25mg378.00€50mg580.00€100mg798.00€1mL*10mM (DMSO)147.00€KB-74935
CAS:KB-74935: enzyme inhibitor, mineralocorticoid blocker, treats cholesterol, hypolipidemia, neurological issues, Alzheimer's.Formula:C19H18ClF4N3O3SPurity:99.4%Color and Shape:SolidMolecular weight:479.88Mitiperstat
CAS:Mitiperstat, a strong MPO inhibitor, helps prevent heart failure and coronary artery disease.Formula:C15H15ClN4OSPurity:98.36%Color and Shape:SolidMolecular weight:334.82Ref: TM-T61028
1mg147.00€5mg356.00€10mg432.00€25mg700.00€50mg888.00€100mg1,243.00€1mL*10mM (DMSO)393.00€ER 50891
CAS:ER-50891 is a potent RARα antagonist, countering retinoic acid inhibition and aiding BMP2-induced osteoblast differentiation.Formula:C29H24N2O2Purity:99.43%Color and Shape:SolidMolecular weight:432.51NEP-IN-1
CAS:NEP-IN-1 is an inhibitor of neutral endopeptidase (NEP, IC50 = 2 nM) and can be used in studies about female sexual arousal disorders.Formula:C21H30ClNO4Purity:99.69%Color and Shape:SolidMolecular weight:395.92Calcium channel-modulator-1
CAS:Calcium channel-modulator-1 is a calcium channel-modulator (IC50:0.8 μM) with specialisation to block aortic constriction.
Formula:C26H24Cl2N2O7SPurity:99.95%Color and Shape:SolidMolecular weight:579.45Setileuton
CAS:Setileuton (MK0633) is a specific 5-LOX inhibitor and can be used in research on asthma and atherosclerosis.
Formula:C22H17F4N3O4Purity:98.85% - 99.35%Color and Shape:SolidMolecular weight:463.38CCT365623
CAS:CCT365623: oral Lysyl Oxidase inhibitor, potent, selective, good pharmacokinetics, anti-metastatic.Formula:C18H17NO4S3Purity:97.299% - 97.63%Color and Shape:SolidMolecular weight:407.53Ref: TM-T26969
1mg86.00€5mg180.00€10mg245.00€25mg374.00€50mg504.00€100mg662.00€200mg875.00€1mL*10mM (DMSO)225.00€WAY-620147
CAS:WAY-620147 inhibits Monoamine Oxidase and can be used for the study of neurological disorders.Formula:C12H16BrN3O2Purity:99.55%Color and Shape:SolidMolecular weight:314.18p-Ethynylphenylalanine
CAS:p-Ethynylphenylalanine (4-Ethynyl-L-phenylalanine), a tryptophan hydroxylase (TPH) inhibitor, is competitive, effective, selective, and reversible, with a Ki ofFormula:C11H11NO2Purity:99.44%Color and Shape:SolidMolecular weight:189.21Xanthine oxidase-IN-1
CAS:Xanthine oxidase-IN-1 is an effective inhibitor of xanthine oxidase with an IC50 value of 6.5 nM.Formula:C16H8F2N2O3Purity:97.36% - 99.22%Color and Shape:SolidMolecular weight:314.24Ref: TM-T10509
1mg139.00€5mg328.00€10mg452.00€25mg672.00€50mg904.00€100mg1,169.00€200mg1,578.00€1mL*10mM (DMSO)279.00€4A3-SC8
CAS:4A3-SC8 is a modular, degradable dendrimer facilitating the extension of survival in aggressive liver cancer models through the delivery of small RNAs [1].Formula:C75H139N3O16S4Purity:99.87%Color and Shape:SolidMolecular weight:1467.18Ecopladib
CAS:Ecopladib inhibits cPLA2α with IC50 of 0.15 μM (micelles) & 0.11 μM (rat blood).
Formula:C39H33Cl3N2O5SPurity:95.15%Color and Shape:SolidMolecular weight:748.11Cudetaxestat
CAS:Cudetaxestat (BLD-0409) is a potent inhibitor of orally active autotaxin.Formula:C21H15Cl2F2N3O2SPurity:99.9%Color and Shape:SolidMolecular weight:482.33Ref: TM-T63190
1mg73.00€5mg161.00€10mg235.00€25mg420.00€50mg627.00€100mg880.00€200mg1,161.00€1mL*10mM (DMSO)166.00€Rilapladib
CAS:Rilapladib (SB 659032) is a selective inhibitor of Lipoprotein-Associated Phospholipase A2(Lp-PLA2, IC50 = 230 pM) and an antagonist of the platelet activatingFormula:C40H38F5N3O3SPurity:99.92%Color and Shape:SolidMolecular weight:735.8Ref: TM-T16751
1mg87.00€5mg215.00€10mg349.00€25mg537.00€50mg745.00€100mg1,108.00€200mg1,504.00€1mL*10mM (DMSO)349.00€Enpp-1-IN-16
CAS:Enpp-1-IN-16 is an ENPP1 inhibitor, yo anti-cancer activity.Enpp-1-IN-16 can be used to study insulin resistance and chondrocalcinosis.Formula:C23H32N4O4Purity:99.87%Color and Shape:SolidMolecular weight:428.52WAY-297848
CAS:WAY-297848 is a novel glucokinase activator for the prevention or treatment of hyperglycemia, diabetes mellitus, obesity, dyslipidemia, and metabolic syndrome.Formula:C13H13ClN2O2SPurity:98.19%Color and Shape:SolidMolecular weight:296.77Mutant IDH1-IN-2
CAS:Mutant IDH1-IN-2 is a inhibitor of mutant Isocitrate dehydrogenase (IDH) proteins, with IC50 of 16.6 nM in Fluorescence biochemical assay, IC50 of ＜22 nM in LS-Formula:C24H31F2N5O2Purity:99.88%Color and Shape:SolidMolecular weight:459.53Ref: TM-T12128
1mg60.00€5mg138.00€10mg224.00€25mg374.00€50mg532.00€100mg718.00€200mg964.00€1mL*10mM (DMSO)137.00€sEH inhibitor-1
TCPU (sEH inhibitor-1) is a potent oral human sEH blocker with IC50s of 0.4 nM (human) and 5.3 nM (mouse).
Color and Shape:SolidPhocaecholic Acid
CAS:Phocaecholic acid, a bile acid, has been identified in the bile of ducks (A. platyrhynchos).Formula:C24H40O5Color and Shape:SolidMolecular weight:408.57GSK 366
CAS:GSK 366 is a potent kynurenine-3-monooxygenase (KMO) inhibitor (IC50s: 0.7 nM and 2.3 nM for P. fluorescens-KMO and human KMO).Formula:C17H16ClN3O4Purity:98%Color and Shape:SolidMolecular weight:361.78ONL-1204
CAS:ONL-1204 is a small molecule, CD95 antigen inhibitor (Fas inhibitor) being developed by ONL Therapeutics for the treatment of retinal detachment.Formula:C71H100N18O16Color and Shape:SolidMolecular weight:1461.66β-Glucuronidase/hCAII-IN-2
β-Glucuronidase/hCAII-IN-2 is a potent inhibitor of β-glucuronidase and hCA II, and their IC50 values were 670.7 μM and 21.77 μM, respectively.Formula:C31H23NO8Color and Shape:SolidMolecular weight:537.52Glucosylceramide synthase-IN-3
Glucosylceramide synthase-IN-3 (BZ1) is a potent, brain-accessible, oral GCS inhibitor with a 16 nM IC50, relevant for Gaucher's disease study.Formula:C21H20FN3O3Color and Shape:SolidMolecular weight:381.4hCAIX/XII-IN-15
CAS:hCAIX/XII-IN-15 (Compound 17β) is an inhibitor of hCA IX and hCA XII, exhibiting Ki values of 0.42 and 4.37 μM, respectively. It demonstrates a pro-apoptotic effect in multiple myeloma cells.Formula:C17H18O4SColor and Shape:SolidMolecular weight:318.387Cephapirin lactone
CAS:Cephapirinlactone is a metabolite of the antibiotic Cephapirin.Formula:C15H13N3O4S2Molecular weight:363.41OMDM169
CAS:OMDM169: potent/selective MAGL inhibitor, raises 2-AG, analgesic via cannabinoid receptors, IC50: 0.13-0.41μM in rat/COS-7, inactive at CB1/CB2.Formula:C25H45NO5Purity:98%Color and Shape:SolidMolecular weight:439.63Zaragozic acid C
CAS:Zaragozic acid C is an effective inhibitor of squalene synthase.Formula:C40H50O14Purity:98%Color and Shape:SolidMolecular weight:754.82PNPLA3 modifier 1
CAS:PNPLA3 Modifier 1 (Compound 10), a modifier of patatin-like phospholipase domain-containing protein 3 (pnpla3), exhibits a geometric mean EC50 of 4.9 nM.Formula:C16H19ClF2N2O4SColor and Shape:SolidMolecular weight:408.85GlcCer (d18:1/18:0)
CAS:GlcCer (d18:1/18:0) (C18 Glucosyl(β) ceramide (d18:1/18:0)) is a sphingolipid with potential applications in research on Parkinson's disease and Lewy body dementia.Formula:C42H81NO8Color and Shape:SolidMolecular weight:728.094(S)-CPP sodium
CAS:(S)-CPP sodium serves as an inhibitor of the branched-chain α-keto acid dehydrogenase complex (BCKDC) kinase, commonly referred to as BDK or keto acid dehydrogenase kinase. As a negative regulator of BCKDC activity, (S)-CPP (IC50 of 6.3 μM) inhibits BDK, which activates the complex, leading to a significant reduction in the levels of leucine/isoleucine and valine in the plasma of wild-type mice.Formula:C9H8ClNaO2Color and Shape:SolidMolecular weight:206.607-Hydroxyrisperidone
CAS:7-Hydroxyrisperidone (7-RispOH) is a metabolite of Risperidone. Risperidone acts as a 5-HT2 receptor blocker, an inhibitor of P-glycoprotein (P-Glycoprotein), and an antagonist of the dopamine D2 receptor.Formula:C23H27FN4O3Color and Shape:SolidMolecular weight:426.4847-APB hydrochloride
CAS:7-APB hydrochloride is a benzofuran compound and serves as a metabolite of 7-MAPB.Formula:C11H14ClNOColor and Shape:SolidMolecular weight:211.688Zolpyridine
CAS:Zolpyridine is a degradation product of Zolpidem tartrate.Formula:C14H14N2OColor and Shape:SolidMolecular weight:226.27Carbonic anhydrase inhibitor 10
CA inhibitor 10 targets MCF-7 cells, IC50: 11.9 μM; potent h CA IX inhibitor, Ki: 6.2 nM. Anti-cancer research.Formula:C14H17N5O3SColor and Shape:SolidMolecular weight:335.38PTP1B-IN-18
PTP1B-IN-18 is an orally active, fully mixed protein tyrosine phosphatase 1B (PTP1B) inhibitor (Ki: 35.2 μM).PTP1B-IN-18 can be used to study type 2 diabetes.Formula:C26H19N3O4SColor and Shape:SolidMolecular weight:469.51CK2 inhibitor 3
CK2 inhibitor 3: potent CK2 blocker, IC50 of 280 nM, suppresses tumor cell growth, highly selective among 320 kinases.Formula:C13H9BrN4O3SColor and Shape:SolidMolecular weight:381.2hCAVII/IX-IN-1
CAS:hCAVII/IX-IN-1 (compound 4) functions as an inhibitor of hCAVII/IX, exhibiting Ki values of 56.5 nM and 38.2 nM, respectively. It is applicable in the field of cancer research.Formula:C7H7N3O2S2Color and Shape:SolidMolecular weight:229.279DC360
CAS:DC360 is a synthetic analog of all-trans retinoic acid (ATRA) that can induce the expression of RARβ. It is useful for studies characterizing the retinoic acid signaling pathway.
Formula:C23H23NO2Color and Shape:SolidMolecular weight:345.434Irafamdastat
CAS:Irafamdastat (BMS-986368) [Example 74] is an inhibitor of FAAH and MAGL, with IC50 values of ≤ 100 nM for human FAAH and 100 nM-1 μM for human MAGL. It exhibits anticonvulsant properties.Formula:C20H21F3N4O4Color and Shape:SolidMolecular weight:438.404-Amino-3-hydroxyphenylalanine
CAS:4-Amino-3-hydroxyphenylalanine (4-AHP) is a photodegradation product of eumelanin. It can be utilized in research focused on the formation of cutaneous melanoma and age-related macular degeneration.Formula:C9H12N2O3Color and Shape:SolidMolecular weight:196.2039(S)-HEPE
CAS:9(S)-HEPE is a monohydroxy fatty acid derived from EPA. The biological activity of 9(S)-HEPE has not been documented.Formula:C20H30O3Color and Shape:SolidMolecular weight:318.45Norfluoxetine
CAS:Norfluoxetine, the active metabolite of the antidepressant Fluoxetine, acts as a selective inhibitor for serotonin uptake.Formula:C16H16F3NOColor and Shape:SolidMolecular weight:295.30YM-355179
CAS:YM-355179 is a novel, selective antagonist of CC chemokine receptor 3 with oral activity.Formula:C33H34FN4O7Purity:98%Color and Shape:SolidMolecular weight:617.64MCTR3
CAS:MCTR3, derived from DHA via maresin 1 in macrophages, hastens tissue healing and reduces inflammation and eicosanoids post-E. coli infection in mice.Formula:C25H37NO5SColor and Shape:SolidMolecular weight:463.63N-Boc-3-hydroxy-1,2,3,6-tetrahydropyridine
CAS:N-Boc-3-hydroxy-1,2,3,6-tetrahydropyridine enhances β-glucocerebrosidase (β-Glucocerebrosidase) activity by 20%. It is used in research on lysosomal storage disorders and other protein accumulation diseases.Formula:C10H17NO3Color and Shape:SolidMolecular weight:199.25Cgs 25155
CAS:Cgs 25155 is an orally active inhibitor of NEP 24.11.Formula:C25H34N2O6SPurity:98%Color and Shape:SolidMolecular weight:490.617(Z),11(Z)-Nonacosadiene
CAS:7(Z),11(Z)-Nonacosadiene, a female fly pheromone, spurs male courtship; it's a C29 diene made by a female-specific elongase.Formula:C29H56Color and Shape:SolidMolecular weight:404.75TKL-IN-2
CAS:TKL-IN-2 (Compound 7m) is a TKL inhibitor with an IC50 of 0.11 mg/L against SvTKL. It exhibits excellent herbicidal activity against Digitaria sanguinalis and Amaranthus retroflexus, while being safe for corn, wheat, soybean, and cotton. TKL-IN-2 is suitable for research in weed control in crop fields.Formula:C23H17ClF3N3OColor and Shape:SolidMolecular weight:443.85L 668411
CAS:L 668411, the 2,3-ditritiated methyl ester of L 659699, inhibits HMG-CoA synthase.Formula:C19H30O5Purity:98%Color and Shape:SolidMolecular weight:338.44Tovinontrine
CAS:Tovinontrine (IMR-687) (IMR-687) is a potent and selective inhibitor of phosphodiesterase-9 (PDE9), designed to target sickle cell disease treatment.Formula:C21H26N6O2Purity:98.8%Color and Shape:SolidMolecular weight:394.476-trans-12-epi-Leukotriene B4
CAS:6-trans-12-epi-Leukotriene B4, a metabolite of arachidonic acid, serves as a potent anti-inflammatory agent.Formula:C20H32O4Color and Shape:SolidMolecular weight:336.47Lipid 12T-O14
CAS:Lipid 12T-O14 is a lipid nanoparticle that facilitates the delivery of local mRNA vaccines and systemic mRNA agents.Formula:C37H66N2O2SColor and Shape:SolidMolecular weight:603.00Turoctocog alfa
CAS:Turoctocog alfa: recombinant FVIII from CHO cells for hemophilia A study.Color and Shape:Solidα-Amylase-IN-10
CAS:α-Amylase-IN-10 (Compound 15n) is an inhibitor of α-Amylase, with an IC50 of 5.00 µM. This compound is applicable for research in type 2 diabetes.Formula:C21H15ClN2O4SColor and Shape:SolidMolecular weight:426.873Pefcalcitol
CAS:Pefcalcitol is a novel antipsoriatic prodrug candidate containing a 16-en-22-oxa-vitamin D3 structure.Formula:C26H34F5NO4Color and Shape:SolidMolecular weight:519.54EB-0156
EB-0156: potent ER α-glucosidase inhibitor, IC50 of 0.0479/ <0.001 μM, N-substituted valerian, broad-spectrum antiviral potential.Formula:C21H32N6O7Color and Shape:SolidMolecular weight:480.5115-epi-PGE1
CAS:15-epi-PGE1 (15R-Prostaglandin E1; 15-Epiprostaglandin E1), a stereoisomer of PGE1, exhibits reduced biological activity [2]. This compound acts as a non-competitive inhibitor of human placental 15-Hydroxyprostaglandin dehydrogenase (15-PGDH), with an inhibitory concentration 50 (IC50) value of 170 μM [1].Formula:C20H34O5Color and Shape:SolidMolecular weight:354.48MolPort-010-778-422
CAS:MolPort-010-778-422 is a high-affinity inhibitor targeting the ACE2 receptor of the SARS-CoV-2 virus. It demonstrates remarkable antiviral activity with an IC50 of 8.9 nM and holds promise for use in studies related to SARS-CoV-2.Formula:C20H26N2O3S2Color and Shape:SolidMolecular weight:406.56SAL-0010042
CAS:SAL-0010042 is an inhibitor of Plasmodium phosphodiesterase β (PDEβ), effectively blocking the hydrolysis of cAMP and cGMP in gametocytes with an IC50 of 48.9 nM, thereby activating PKG and inhibiting the growth and development of Plasmodium (IC50s for 3D7 and Dd2 are 142 nM and 218 nM, respectively). It also inhibits hPDE5 and hPDE6 with IC50 values of 632 nM and 73 nM, respectively.Formula:C15H15FN4OColor and Shape:SolidMolecular weight:286.304
