Metabolism
Metabolism inhibitors are compounds that interfere with metabolic pathways, altering the production and utilization of energy within cells. These inhibitors are used to study the regulation of metabolism, the role of metabolic pathways in diseases like cancer and diabetes, and to develop new therapeutic strategies. Metabolism inhibitors can target various enzymes and processes involved in glycolysis, fatty acid oxidation, and other metabolic functions. At CymitQuimica, we offer a wide range of high-quality metabolism inhibitors to support your research in biochemistry, metabolic disorders, and drug development.
Subcategories of "Metabolism"
- AhR(41 products)
- Aminopeptidase(67 products)
- CETP(18 products)
- Carbonic Anhydrase(177 products)
- Casein Kinase(130 products)
- DHFR(32 products)
- Decarboxylase(4 products)
- Dehydrogenase(267 products)
- FAAH(63 products)
- FXR(58 products)
- Factor Xa(80 products)
- Fatty Acid Synthase(32 products)
- Ferroptosis(215 products)
- GR(3 products)
- GSNOR(3 products)
- Glucokinase(53 products)
- HIF/HIF Prolyl-Hydroxylase(142 products)
- HMG-CoA Reductase(32 products)
- Hydroxylase(30 products)
- IDO(82 products)
- LDL(8 products)
- Lipase(96 products)
- Lipid(59 products)
- Lipoxygenase(124 products)
- MAO(87 products)
- MPO(2 products)
- NAMPT(36 products)
- P450(6 products)
- PAI-1(25 products)
- PDE(166 products)
- PED(1 products)
- PKM(15 products)
- PPAR(164 products)
- Phospholipase(82 products)
- ROR(42 products)
- Retinoid Receptor(29 products)
- SGK(11 products)
- Thioredoxin(12 products)
- Transferase(30 products)
- Transporter(42 products)
- UGT(4 products)
- Xanthine Oxidase (XO) Inhibitors(9 products)
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Found 8595 products of "Metabolism"
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MGAT2-IN-2
CAS:<p>MGAT2-IN-2 is a potent inhibitor of acyl CoA:monoacylglycerol acyltransferase 2 (MGAT2) (IC50 of 3.4 nM).</p>Formula:C26H21F5N4O4SPurity:98%Color and Shape:SolidMolecular weight:580.53(Rac)-CP-609754
CAS:<p>LNK754 is a farnesyltransferase inhibitor. It is used for the treatment of cancer and Alzheimer's disease.</p>Formula:C29H22ClN3O2Purity:98%Color and Shape:SolidMolecular weight:479.9612(R)-HEPE
CAS:<p>12(R)-HEPE, a monohydroxy fatty acid derived from EPA in the eggs of the sea urchin S. purpuratus, has a biological activity that, while not extensively documented, may resemble that of 12(R)-HETE (Catalog No.34560).</p>Formula:C20H30O3Color and Shape:SolidMolecular weight:318.5GNE-6468
CAS:<p>GNE-6468 is a potent and selective agonist of RORγ(RORc) (EC50: 13 nM for HEK-293 cell).</p>Formula:C23H16ClN3O4Color and Shape:SolidMolecular weight:433.84Anticancer agent 121
CAS:<p>Anticancer agent 121, a human lactate dehydrogenase A (hLDHA) inhibitor, exhibits potent anticancer activities, suitable for use in anticancer research [1].</p>Formula:C19H18N2O3SColor and Shape:SolidMolecular weight:354.42N-Stearoyl Taurine
CAS:<p>N-Arachidonoyl dopamine (NADA) and N-Arachidonoyl serine (ARA-S), among various arachidonoyl amino acids, have been extracted from bovine brain, while a novel series of fatty acyl amides of taurine were unearthed in rat brain through mass spectral lipidomic analysis, indicating the discovery of a new class of compounds also located in the kidney. These compounds are known to activate members of the transient receptor potential (TRP) family of calcium channels. Notably, N-Stearoyl taurine emerges as a significant amino-acyl endocannabinoid identified in rat brain lipidomics profiling.</p>Formula:C20H41NO4SColor and Shape:SolidMolecular weight:391.61ICMT-IN-39
CAS:<p>ICMT-IN-39, also known as compound 18, functions as an inhibitor of ICMT with an IC50 value of 0.031 µM [1].</p>Formula:C22H29NOColor and Shape:SolidMolecular weight:323.47EMD638683 S-Form
CAS:<p>EMD638683 is a highly selective SGK1 inhibitor with IC50 of 3 μM. EMD638683 S-Form is the S-form of EMD638683.</p>Formula:C18H18F2N2O4Color and Shape:SolidMolecular weight:364.34Docosatrienoic Acid
CAS:<p>Docosatrienoic acid is a rare omega-3 fatty acid; Ki value is 5×M, which inhibits the binding of LTB4 to porcine neutrophil membrane.</p>Formula:C22H38O2Purity:98%Color and Shape:SolidMolecular weight:334.54ICMT-IN-50
CAS:<p>ICMT-IN-50 (compound 3) serves as an inhibitor of ICMT with an IC50 value of 0.31 µM [1].</p>Formula:C27H31NO3Color and Shape:SolidMolecular weight:417.54Methyl γ-Linolenyl Fluorophosphonate
CAS:<p>MγLnFP, an analog of methyl arachidonyl fluozophosphonate (MAFP), holds significance in pharmacological research due to its potential as an inhibitor of phospholipases, FAAH, and its role as a CB receptor ligand. However, the properties and effects of the γ-linolenyl variant of MAFP remain to be fully explored.</p>Formula:C19H34FO2PColor and Shape:SolidMolecular weight:344.451Lignoceroyl Ethanolamide
CAS:<p>Lignoceroyl ethanolamide, a fatty N-acyl ethanolamine within the endocannabinoid family, is derived from lignoceric acid, which is found in relatively high concentrations in rat cerebrospinal fluid. However, the specific function and significance of this metabolite remain unclear.</p>Formula:C26H53NO2Color and Shape:SolidMolecular weight:411.715OSMI-1
CAS:<p>OSMI-1: cell-permeable OGT inhibitor, blocks O-GlcNAcylation (IC50: 2.7 μM), no effect on other cell glycans.</p>Formula:C28H25N3O6S2Purity:96.79% - 99.39%Color and Shape:SolidMolecular weight:563.642-Stearoyl-sn-glycero-3-PC
CAS:<p>2-Stearoyl-sn-glycero-3-phosphatidylcholine (2-Stearoyl-sn-glycero-3-PC) is a lysophospholipid characterized by the presence of stearic acid at the sn-2 position. This compound has been identified in the myocardium of rabbits.</p>Formula:C26H54NO7PColor and Shape:SolidMolecular weight:523.68ICMT-IN-15
CAS:<p>ICMT-IN-15 (compound 51) serves as an ICMT inhibitor with an IC50 value of 0.032 μM [1].</p>Formula:C21H25ClFNOColor and Shape:SolidMolecular weight:361.88ICMT-IN-9
CAS:<p>ICMT-IN-9 (compound 47) is a potent ICMT inhibitor with an IC50 value of 0.16 μM [1].</p>Formula:C22H28FNO2Color and Shape:SolidMolecular weight:357.46FTI-2153
CAS:<p>FTI-2153 inhibits farnesyltransferase with 1.4 nM IC50, >3000x more effective on H-Ras than Rap1A.</p>Formula:C25H30N4O3SColor and Shape:SolidMolecular weight:466.6Dioleyldimethylammonium chloride
CAS:<p>Dioleyldimethylammonium chloride (DODAC) is a cationic lipid utilized as a transfection reagent [1].</p>Formula:C38H76ClNColor and Shape:SolidMolecular weight:582.47ICMT-IN-38
CAS:<p>ICMT-IN-38 (Compound 42) is an ICMT inhibitor, demonstrating an IC50 value of 0.049 μM [1].</p>Formula:C22H28ClNOColor and Shape:SolidMolecular weight:357.92GLUT4 activator 1
CAS:<p>GLUT4 activator 1 is a potent glucose transporter type 4 (GLUT4) translocation activator (EC50: 0.14 μM).</p>Formula:C23H21FN4O3SPurity:98%Color and Shape:SolidMolecular weight:452.5L-CCG-lll
CAS:<p>inhibitor of both glial and neuronal uptake of glutamate, aspartate and cysteate.</p>Formula:C6H9NO4Purity:98%Color and Shape:SolidMolecular weight:159.14Quercetin 7-glucuronide
CAS:<p>Quercetin 7-glucuronide (Quercetin 7-O-β-glucuronide), a Quercetin metabolite found in Madagascarian Uncarina species, has the capability to inhibit LDL</p>Formula:C21H18O13Purity:98%Color and Shape:SolidMolecular weight:478.36RP 70676
CAS:<p>RP 70676 is a potent ACAT inhibitor(rat and rabbit ACAT with IC50 of 25 and 44 nM ).</p>Formula:C25H28N4SPurity:99.92%Color and Shape:SolidMolecular weight:416.58MetAP2-IN-1
CAS:<p>MetAP2-IN-1 is a selective inhibitor of MetAP2, a target involved in angiogenesis-related conditions, suitable for research applications [1].</p>Formula:C8H6BrN3Purity:98%Color and Shape:SolidMolecular weight:224.06AZD1092
CAS:<p>AZD1092 is the glucokinase enzyme activator.</p>Formula:C24H26N4O5Purity:98%Color and Shape:SolidMolecular weight:450.49(±)-HIP-A
CAS:<p>(±)-HIP-A is an excitatory amino acid transporter blocker.</p>Formula:C6H8N2O4Purity:98%Color and Shape:SolidMolecular weight:172.141,2-Distearoyl-3-Oleoyl-rac-glycerol
CAS:<p>1,2-Distearoyl-3-oleoyl-rac-glycerol, a triacylglycerol, comprises stearic acid at the sn-1 and sn-2 positions and oleic acid at the sn-3 position. This compound is present in cocoa butter and vegetable oils.</p>Formula:C57H108O6Color and Shape:SolidMolecular weight:889.46Gisadenafil
CAS:<p>Gisadenafil (UK-369003) is a selective inhibitor of phosphodiesterase 5 (PDE5) with an IC50 of 3.6 nM and prevents degradation of cGMP.</p>Formula:C23H33N7O5SPurity:98.82% - 99.50%Color and Shape:SolidMolecular weight:519.621,2-Dilinoleoyl-sn-glycero-3-PC
CAS:<p>1,2-Dilinoleoyl-sn-glycero-3-PC (Dilinoleoyllecithin), a phospholipid, finds application in the production of artificial membranes [1].</p>Formula:C44H80NO8PColor and Shape:SolidMolecular weight:782.097MMV009085
CAS:<p>MMV009085 is a potent inhibitor of the Plasmodium falciparum hexose transporter (Pf HT1), with potential as an anti-malarial agent.</p>Formula:C22H22N2O6Color and Shape:SolidMolecular weight:410.42PDE5-IN-2
CAS:<p>PDE5-IN-2 is a potent, highly selective, and orally active inhibitor of PDE5(IC50 of 0.31 nM)</p>Formula:C25H21N3O6SPurity:98%Color and Shape:SolidMolecular weight:491.52Niraxostat
CAS:<p>Niraxostat (Y-700) is one of the isocytosine derivatives as xanthine oxidase inhibitors.</p>Formula:C16H17N3O3Purity:98.13%Color and Shape:SolidMolecular weight:299.32L-hydroxylysine dihydrochloride
CAS:<p>L-hydroxylysine dihydrochloride , is formed by posttranslational hydroxylation of some lysine residues. It is an amino acid, is exclusive to collagen protein.</p>Formula:C6H16Cl2N2O3Purity:98%Color and Shape:SolidMolecular weight:235.11RORγt Inverse agonist 6
CAS:<p>RORγt Inverse agonist 6 is an agonist of RORγt inverse. RORγt Inverse agonist 6 can be used in research on Th17-driven autoimmune diseases.</p>Formula:C28H29ClN6O5Purity:99.52%Color and Shape:SolidMolecular weight:565.02NOX2-IN-2
CAS:<p>NOX2-IN-2 (compound 33) is a potent inhibitor of NOX2, disrupting the p47phox-p22phox protein-protein interaction with a dissociation constant (K i) of 0.24 μM.</p>Formula:C25H25N7O3Color and Shape:SolidMolecular weight:471.515-Lipoxygenase-In-1
CAS:<p>5-Lipoxygenase-In-1 (compound example 4.10) is a 5-Lipoxygenase inhibitor.</p>Formula:C23H28N4O2SColor and Shape:SolidMolecular weight:424.56ICMT-IN-54
CAS:<p>ICMT-IN-54 (compound 7c), an adamantyl analogue, serves as an ICMT inhibitor with an IC50 value of 12.4 μM, targeting the methylation process facilitated by</p>Formula:C29H45NO3SColor and Shape:SolidMolecular weight:487.74TMP780
CAS:<p>TMP780 is an inverse RORγt agonist (IC50: 13 nM). RORγt is a tractable drug target for the treatment of cutaneous inflammatory disorders.</p>Formula:C31H30N2O4Purity:98%Color and Shape:SolidMolecular weight:494.58ATX-001
CAS:<p>ATX-001, an ionizable cationic lipid, is utilized in the creation of lipid nanoparticles (LNPs) for mRNA delivery [1].</p>Formula:C40H74N2O5SColor and Shape:SolidMolecular weight:695.09GNE-618
CAS:<p>GNE-618 is a potent and orally active inhibitor of nicotinamide phosphoribosyltransferase (IC50: 6 nM).</p>Formula:C21H15F3N4O3SColor and Shape:SolidMolecular weight:460.43EMD638683 R-Form
CAS:<p>EMD638683 is a highly selective SGK1 inhibitor with IC50 of 3 μM. EMD638683 R-Form is the R-form of EMD638683.</p>Formula:C18H18F2N2O4Color and Shape:SolidMolecular weight:364.34XL041
CAS:<p>XL041 (BMS-852927) is an agonist of LXRβ-selective.</p>Formula:C29H28Cl2F2N2O4SPurity:98%Color and Shape:SolidMolecular weight:609.51LFHP-1c
CAS:<p>LFHP-1c, a neuroprotective PGAM5 inhibitor, demonstrates efficacy in preserving blood-brain barrier integrity following ischemic stroke.</p>Formula:C55H64N6O4Purity:98.07%Color and Shape:SolidMolecular weight:873.13Safinamide Acid
CAS:<p>Safinamide acid, a potential impurity in commercial safinamide preparations and a degradation product of safinamide under thermal and oxidative stress, is encountered in the pharmaceutical formulation process.</p>Formula:C17H18FNO3Color and Shape:SolidMolecular weight:303.33Magmas-IN-1
CAS:<p>Magmas-IN-1 (compound 9), a small molecule Magmas inhibitor (SMMI), targets the mitochondria-associated granulocyte-macrophage colony-stimulating factor (GM-CSF</p>Formula:C20H27N3OPurity:98%Color and Shape:SolidMolecular weight:325.45CI-1044
CAS:<p>CI-1044 is an inhibitor of PDE4 (IC50s: 0.29, 0.08, 0.56, 0.09 μM for PDE4A5, PDE4B2, PDE4C2 and PDE4D3).</p>Formula:C23H19N5O2Color and Shape:SolidMolecular weight:397.43C14-SPM
CAS:<p>C14-SPM, a branched-chain polyamine lipidoid, facilitates the delivery of siRNA [1].</p>Formula:C94H194N4O6Color and Shape:SolidMolecular weight:1476.57Raloxifene Bismethyl Ether hydrochloride
CAS:<p>Raloxifene Bismethyl Ether hydrochloride is a Raloxifene metabolite and an estrogen receptor inactive compound on which both hydroxyl groups are absent.</p>Formula:C30H32ClNO4SPurity:98%Color and Shape:SolidMolecular weight:538.1ICMT-IN-5
CAS:<p>ICMT-IN-5 (compound 46) is an ICMT inhibitor with an IC50 value of 0.3 μM [1].</p>Formula:C22H28FNOColor and Shape:SolidMolecular weight:341.46PF-04957325
CAS:<p>PF-04957325 is an inhibitor of PDE8.PF-04957325 has an IC50 of 0.7 nM for PDE8A.PF-04957325 can be used for the study of autoimmune encephalomyelitis.</p>Formula:C14H15F3N8OSPurity:99.02%Color and Shape:SolidMolecular weight:400.38
