Metabolism
Metabolism inhibitors are compounds that interfere with metabolic pathways, altering the production and utilization of energy within cells. These inhibitors are used to study the regulation of metabolism, the role of metabolic pathways in diseases like cancer and diabetes, and to develop new therapeutic strategies. Metabolism inhibitors can target various enzymes and processes involved in glycolysis, fatty acid oxidation, and other metabolic functions. At CymitQuimica, we offer a wide range of high-quality metabolism inhibitors to support your research in biochemistry, metabolic disorders, and drug development.
Subcategories of "Metabolism"
- AhR(42 products)
- Aminopeptidase(76 products)
- CETP(20 products)
- Carbonic Anhydrase(196 products)
- Casein Kinase(138 products)
- DHFR(32 products)
- Decarboxylase(4 products)
- Dehydrogenase(302 products)
- FAAH(64 products)
- FXR(62 products)
- Factor Xa(85 products)
- Fatty Acid Synthase(37 products)
- Ferroptosis(226 products)
- GR(3 products)
- GSNOR(3 products)
- Glucokinase(57 products)
- HIF/HIF Prolyl-Hydroxylase(146 products)
- HMG-CoA Reductase(34 products)
- Hydroxylase(36 products)
- IDO(84 products)
- LDL(7 products)
- Lipase(107 products)
- Lipid(61 products)
- Lipoxygenase(134 products)
- MAO(87 products)
- MPO(2 products)
- NAMPT(40 products)
- P450(6 products)
- PAI-1(26 products)
- PDE(169 products)
- PED(1 products)
- PKM(17 products)
- PPAR(170 products)
- Phospholipase(86 products)
- ROR(47 products)
- Retinoid Receptor(22 products)
- SGK(10 products)
- Thioredoxin(12 products)
- Transferase(29 products)
- Transporter(45 products)
- UGT(4 products)
- Xanthine Oxidase (XO) Inhibitors(9 products)
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Found 9182 products of "Metabolism"
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sEH inhibitor-2
SEH inhibitor-2 is an orally active sEH blocker (IC50=0.9 nM) with predicted 71.2-88.4% absorption, potentially aiding cardiovascular health.Formula:C23H18N4O3Color and Shape:SolidMolecular weight:398.41L-690330 hydrate
L-690330 hydrate inhibits IMPase; Ki: 0.30 μM (human), 0.42 μM (bovine cortex); 0.27 μM (recom. human), 0.19 μM (bovine).Formula:C8H14O9P2Color and Shape:SolidMolecular weight:316.14Monoamine oxidase/Aromatase-IN-1
Compound 2q: Dual MAO/aromatase inhibitor; IC50: 39 nM (MAO-B), 31 nM (aromatase). Useful in neurological/breast cancer research.Formula:C19H19N3O3SColor and Shape:SolidMolecular weight:369.44Miaosporone A
Miaosporone A: angucyclic quinone, cytotoxic to MCF-7, NCI-H187, Vero cells; anti-TB and anti-malaria with IC50 of 2.4 μM, 2.5 μM.Formula:C19H18O5Color and Shape:SolidMolecular weight:326.34Raloxifene N-Oxide
CAS:Raloxifene N-Oxide is a Raloxifene oxidative degradation product.Formula:C28H27NO5SPurity:98%Color and Shape:SolidMolecular weight:489.58Pyripyropene A
CAS:Pyripyropene A is a potent and selective inhibitor of sterol O-acyltransferase 2 (SOAT2)/acyl-coenzyme A:cholesterol acyltransferase 2 (ACAT2)(IC50 of 0.07 μM).Formula:C31H37NO10Purity:98%Color and Shape:SolidMolecular weight:583.63AChE/PDE4-IN-1
AChE/PDE4-IN-1, compound 12c, dual inhibitor; IC50: 0.28μM for AChE, 1.88μM for PDE4D, may reduce Alzheimer's neuroinflammation.Formula:C23H28N2O3Color and Shape:SolidMolecular weight:380.48Tabimorelin hemifumarate
CAS:orally active ghrelin receptor (GHS-R1a) agonistFormula:C32H40N403C4H404Purity:98%Color and Shape:SolidMolecular weight:586.72Desmonomethylpromazine
CAS:Desmonomethylpromazine is a demethylated metabolite of Promazine that can penetrate the brain. It enters red blood cells and tissues via passive diffusion and is distributed in organs such as the lungs, liver, and kidneys in rats.Formula:C16H18N2SColor and Shape:SolidMolecular weight:270.39Clopidogrel-β-D-glucuronide
CAS:Clopidogrel-β-D-glucuronide is a metabolite of Clopidogrel. It directly interacts with the CYP2C8 enzyme and strongly inhibits the hepatic enzyme CYP2C8.Formula:C21H22ClNO8SColor and Shape:SolidMolecular weight:483.919RORγt inverse agonist 34
CAS:RORγt inverse agonist 34 (compound 5a) is an inverse agonist for RORγt, exhibiting an IC50 of 0.094 μM for the inhibition of RORγt-LBD. This compound is utilized in psoriasis research.Formula:C31H37N3O3SColor and Shape:SolidMolecular weight:531.709ATX inhibitor 12
Oral ATX inhibitor 12 (IC50: 1.72 nM) at 60 mg/kg prevents lung damage in C57Bl/6J mice.
Formula:C30H34FN5O2Color and Shape:SolidMolecular weight:515.62HIF-1α-IN-5
HIF-1α-IN-5 is an inhibitor of HIF-1α with an IC 50 value of 24 nM in HEK293T cells that also inhibits the activity of MAO-A.Formula:C16H15N3O2Color and Shape:SolidMolecular weight:281.31GSK2945 hydrochloride
GSK2945 HCl is a specific Rev-erbα antagonist, EC50: 21.5 μM (mouse), 20.8 μM (human), increases cholesterol 7α-hydroxylase.Formula:C20H19Cl3N2O2SColor and Shape:SolidMolecular weight:457.8RORγt/DHODH-IN-3
RORγt/DHODH-IN-3 (compound (S)-14d) is a potent, orally active dual inhibitor of RORγt (IC50: 0.098 μM) and DHODH (IC50: 0.432 μM).RORγt/DHODH-IN-1 hasFormula:C24H26ClF6N3O3SColor and Shape:SolidMolecular weight:585.99Lipoxin A5
CAS:LXA5 is made from EPA by leukocytes, contracts guinea pig lungs like LXA4/LXB4, but doesn't dilate aorta.Formula:C20H30O5Color and Shape:SolidMolecular weight:350.45NNC 55-0396
CAS:NNC 55-0396: Selective T-type calcium channel blocker, IC50 6.8 μM, inhibits human ovarian cancer cell growth.Formula:C30H40Cl2FN3O2Purity:99.00%Color and Shape:SolidMolecular weight:564.56Ref: TM-T12238
1mg66.00€5mg126.00€10mg202.00€25mg354.00€50mg550.00€100mg787.00€1mL*10mM (DMSO)160.00€PDE4-IN-14
CAS:PDE4-IN-14 (Compound 1) serves as an inhibitor of phosphodiesterase 4 (PDE4), applicable in research concerning diseases associated with PDE4, includingFormula:C19H20F2N4O3SColor and Shape:SolidMolecular weight:422.45PF-07202954
CAS:PF-07202954, a weakly basic diacylglycerol O-acyltransferase 2 (DGAT2) inhibitor, exhibits an inhibition concentration half-maximum (IC50) of 10 nM againstFormula:C22H23FN6O3Purity:98%Color and Shape:SolidMolecular weight:438.45PF-06795071
CAS:PF-06795071 is an effective and selective covalent inhibitor of MAGL (IC50: 3 nM).Formula:C18H17F4N3O3Purity:98%Color and Shape:SolidMolecular weight:399.34FTI 276 TFA
CAS:FTI 276 TFA targets plasmodium falciparum & humans, inhibits PFT with IC50s: 0.9 nM (parasite) & 0.5 nM (human).Formula:C23H28F3N3O5S2Color and Shape:SolidMolecular weight:547.61FTI-2148
CAS:FTI-2148 blocks RAS-related FT-1 & GGT-1; IC50: 1.4 nM & 1.7 μM.Formula:C24H28N4O3SPurity:98%Color and Shape:SolidMolecular weight:452.57RWJ-445167
CAS:RWJ-445167 is a thrombin and factor Xa dual inhibitor(Ki of 4.0 nM and 230 nM, respectively), with potent antithrombotic activity.Formula:C18H24N6O5SPurity:98%Color and Shape:SolidMolecular weight:436.49T-3764518
CAS:T-3764518 is a novel and potent inhibitor of stearoyl coenzyme A desaturase (SCD)(IC50 of 4.7 nM).Formula:C20H17F6N5O2Purity:98%Color and Shape:SolidMolecular weight:473.37Casein kinase 1δ-IN-18
CAS:Casein kinase1δ-IN-18 (compound 660) is an inhibitor of casein kinase 1δ (CK1δ), which can be utilized for research in neurodegenerative diseases.Formula:C16H12ClN3O2S2Color and Shape:SolidMolecular weight:377.8687-APB hydrochloride
CAS:7-APB hydrochloride is a benzofuran compound and serves as a metabolite of 7-MAPB.Formula:C11H14ClNOColor and Shape:SolidMolecular weight:211.68813(R)-HODE
CAS:13(R)-HODE, produced from linoleic acid, inhibits platelet aggregation (IC50=2.7μM) and is found in bovine endothelial cells.Formula:C18H32O3Color and Shape:SolidMolecular weight:296.44LASSBio-1632
LASSBio-1632: Novel anti-asthmatic, blocks PDE4A/D, reduces AHR & lung TNF-α, crosses BBB.Formula:C18H20N2O6SColor and Shape:SolidMolecular weight:392.43BI-4916
CAS:BI-4916 is a phosphoglycerate dehydrogenase (PHGDH) inhibitor that inhibits SSP and reduces cancer cell migration.Formula:C23H24Cl2N2O6SPurity:98.55%Color and Shape:SolidMolecular weight:527.42GSK864
CAS:GSK864 is an inhibitor of isocitrate dehydrogenase 1 (IDH1) mutant. GSK864 inhibits IDH1 mutants R132C, R132H, and R132G (IC50: 8.8, 15.2, and 16.6 nM).Formula:C30H31FN6O4Purity:97.07%Color and Shape:SolidMolecular weight:558.6Inosine 5′-diphosphate sodium
CAS:Inosine 5'-diphosphate sodium, a purine ribonucleoside diphosphate with inosine as its nucleobase, plays a role in intracellular energy metabolism and signal transduction processes.Formula:C10H13N4Na3O12P2Color and Shape:SolidMolecular weight:512.15Nampt-IN-14
CAS:Nampt-IN-14 (example 3) is an effective NAMPT inhibitor with an IC50 of 0.2 nM, suited for use in the synthesis of antibody-drug conjugates (ADCs).Formula:C33H35N7O2Color and Shape:SolidMolecular weight:561.68Ranosidenib
CAS:Ranolisib is an isocitrate dehydrogenase (IDH) inhibitor known for its antitumor activity.Formula:C15H16F9N5OColor and Shape:SolidMolecular weight:453.31Lecufexor
CAS:Lecufexor is an agonist of the farnesoid X receptor (FXR).Formula:C32H21Cl3N2O5Color and Shape:SolidMolecular weight:619.88JA2
CAS:JA2 is an inhibitor of metalloendopeptidase 24.15 that enhances the hypotensive response to bradykinin in rats.Formula:C33H38N4O8Color and Shape:SolidMolecular weight:618.68RORγt inverse agonist 32
CAS:RORγt inverse agonist 32 (compound b14) exhibits oral activity and can be utilized in inflammatory research studies.Formula:C24H28F3NO5SColor and Shape:SolidMolecular weight:499.54Alkannin
CAS:Alkannin: potent, tumor-specific PKM2 inhibitor; non-inhibitory to PKM1/PKL; potential anticancer agent.Formula:C16H16O5Color and Shape:SolidMolecular weight:288.3Porphobilinogen
CAS:Porphobilinogen act as a phytotoxin, a metabotoxin, and a neurotoxin.Formula:C10H14N2O4Purity:98%Color and Shape:SolidMolecular weight:226.23DG013A
CAS:DG013A inhibits ERAP1 & ERAP2 (IC50: 33 nM & 11 nM) to research autoimmune diseases & cancer.Formula:C27H37N4O4PColor and Shape:SolidMolecular weight:512.58Asimicin
CAS:Asimicin is a effective complex I inhibitor.Formula:C37H66O7Purity:98%Color and Shape:SolidMolecular weight:622.92Propofol sulfate sodium
CAS:Propofolsulfate (sodium) is a metabolite of Propofol.Formula:C12H17NaO4SColor and Shape:SolidMolecular weight:280.316BMS-185354
CAS:BMS-185354 is a selective RARγ activator with an EC50 value of 28 nM, offering potential for cancer research.Formula:C26H27NO3Color and Shape:SolidMolecular weight:401.497Indoluidin E
Indoluidin E selectively inhibits DHODH and has an inhibitory effect on cancer cell growth.Formula:C28H30N4O2Color and Shape:SolidMolecular weight:454.56ABT-046
CAS:ABT-046 is an orally active, selective, and highly efficient Diacylglycerol Acyltransferase 1 (DGAT-1) inhibitor that can be used in metabolic disease research.Formula:C20H22N4O2Purity:98.13%Color and Shape:SolidMolecular weight:350.41Keto lovastatin
CAS:Keto lovastatin is an impurity of lovastatin with antibacterial properties. Lovastatin is a cell-permeable HMG-CoA reductase (HMG-CoA reductase) inhibitor used to reduce cholesterol levels.Formula:C24H34O6Color and Shape:SolidMolecular weight:418.523PDE1-IN-7
CAS:PDE1-IN-7 (Compound 13h), with an IC50 value of 10 nM, selectively inhibits bPDE1. This compound demonstrates significant anti-fibrotic effects in a BDL-induced liver fibrosis rat model and is useful for research purposes in studying liver fibrosis [1].Formula:C32H36F2N2O6SMolecular weight:614.7NPD10084
CAS:NPD10084 is an inhibitor of pyruvate kinase PKM2 that blocks non-glycolytic signaling in cancer cells by disrupting PKM2's interaction with β-catenin or STAT3, thus inhibiting downstream pathways. It demonstrates antiproliferative effects against colorectal cancer cells both in vitro and in vivo [1].Formula:C21H19N3O2Color and Shape:SolidMolecular weight:345.39ALOX15-IN-1
ALOX15-IN-1 (8b) inhibits rabbit/human ALOX15; IC50: 0.04 μM for LA, 2.06 μM for AA.Formula:C24H31N3O5SColor and Shape:SolidMolecular weight:473.59TS010
TS010 is a highly potent inhibitor of GLO-I, with an IC50 value of 0.57 μM. It holds significant promise for advancements in cancer research [1].Formula:C16H12N4O4SColor and Shape:SolidMolecular weight:356.36EGFR/VEGFR2-IN-2
EGFR/VEGFR2-IN-2 (compound 4b) serves as a dual inhibitor of VEGFR-2 and EGFR.Formula:C24H15FO3Color and Shape:SolidMolecular weight:370.37
