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Metabolism

Metabolism

Metabolism inhibitors are compounds that interfere with metabolic pathways, altering the production and utilization of energy within cells. These inhibitors are used to study the regulation of metabolism, the role of metabolic pathways in diseases like cancer and diabetes, and to develop new therapeutic strategies. Metabolism inhibitors can target various enzymes and processes involved in glycolysis, fatty acid oxidation, and other metabolic functions. At CymitQuimica, we offer a wide range of high-quality metabolism inhibitors to support your research in biochemistry, metabolic disorders, and drug development.

Subcategories of "Metabolism"

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Found 8626 products of "Metabolism"

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  • Reticulol

    CAS:
    <p>Reticulol is an isocoumarin derivative produced by certain species of Streptomyces.</p>
    Formula:C11H10O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:222.19
  • GLUT1-IN-1


    <p>GLUT1-IN-1 inhibits GLUT1; cytotoxic to HeLa, A549, HepG2 (IC50: 5.49, 11.14, 8.73 μM); potential in PDT and cancer research.</p>
    Formula:C25H31BF2I2N6O7
    Color and Shape:Solid
    Molecular weight:830.17
  • α-Glucosidase-IN-85


    <p>α-Glucosidase-IN-85 (Compound 8D1) functions as an inhibitor of α-Glucosidase, with an IC50 of 5.43 μM. This compound is useful for research related to type 2 diabetes.</p>
    Color and Shape:Odour Solid
  • Casein kinase 1δ-IN-14

    CAS:
    <p>Casein kinase 1δ-IN-14 (WAY-637081) can be used to study atherosclerosis-related cardiovascular disease.</p>
    Formula:C17H11ClN4O2
    Purity:99.74%
    Color and Shape:Solid
    Molecular weight:338.75
  • Calcium 2-oxoglutarate

    CAS:
    <p>Calcium 2-oxoglutarate is an intermediate in the production of GTP or ATP in the Krebs cycle. It is a reversible inhibitor of tyrosinase (IC50: 15 mM).</p>
    Formula:C5H8CaO5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:188.192
  • Venetoclax N-oxide

    CAS:
    <p>Venetoclax N-oxide is a byproduct of potent, oral Bcl-2 inhibitor Venetoclax (ABT-199/GDC-0199) with Ki &lt;0.01 nM.</p>
    Formula:C45H50ClN7O8S
    Color and Shape:Solid
    Molecular weight:884.44
  • α-Amylase/α-Glucosidase-IN-6


    <p>α-Amylase/α-Glucosidase-IN-6 (compound 5j) serves as a potent dual inhibitor of both α-amylase and α-glucosidase, exhibiting IC50 values of 17.0 µM and 40.1 µM</p>
    Color and Shape:Odour Solid
  • Nampt-IN-10 trihydrochloride


    <p>Nampt-IN-10 trihydrochloride, a NAMPT inhibitor, is effective on A2780 &amp; CORL23 cells (IC50: 5/19 nM); potential ADC payload.</p>
    Formula:C27H31Cl3FN5O2
    Color and Shape:Solid
    Molecular weight:582.92
  • ATX inhibitor 7

    CAS:
    <p>ATX inhibitor 7 is a autotaxin inhibitor and shows good oral exposure.</p>
    Formula:C21H22F3N7O2
    Color and Shape:Solid
    Molecular weight:461.449
  • ML171

    CAS:
    <p>Compound PDK0326, with CAS No. 6631-94-3, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0326 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>
    Formula:C14H11NOS
    Color and Shape:Mustard-Colored Powder
    Molecular weight:241.3
  • VDR agonist 2


    <p>VDR agonist 2 (compound 16i), a vitamin D receptor (VDR) agonist, effectively inhibits TGF-β1-induced hepatic stellate cell (HSC) activation, demonstrating</p>
    Formula:C20H21F3O3
    Color and Shape:Solid
    Molecular weight:366.37
  • Carboxylesterase-IN-1

    CAS:
    <p>Carboxylesterase-IN-1, a pesticide inhibits carboxylesterase at 50 μg/mL, akin to triphenyl phosphate.</p>
    Formula:C30H37BrN2O5
    Color and Shape:Solid
    Molecular weight:585.539
  • Tetomilast

    CAS:
    <p>Tetomilast (OPC-6535) is a phosphodiesterase-4 (PDE4) inhibitor, potentially effective in treating inflammatory bowel disease (IBD) and chronic obstructive</p>
    Formula:C19H18N2O4S
    Color and Shape:Solid
    Molecular weight:370.42
  • FUT8-IN-1


    <p>FUT8-IN-1 (Compound 37) is an inhibitor of α-1,6-fucosyltransferase (FUT8), with a dissociation constant (KD) of 49 nM and an IC50 around 50 µM. In the presence of FUT8, FUT8-IN-1 forms a highly active naphthoquinone imine intermediate, thereby inhibiting FUT8's enzymatic activity.</p>
    Formula:C23H25ClN2O
    Color and Shape:Solid
    Molecular weight:380.91
  • Cho-Arg (trifluoroacetate salt)

    CAS:
    <p>Cho-Arg is a cholesterol-based cationic lipid that complexes with DNA, aids transfection, and is cytotoxic at 88.5 μg/ml IC50.</p>
    Formula:C43H71F6N5O7
    Color and Shape:Solid
    Molecular weight:884.059
  • Previtamin D3

    CAS:
    <p>Previtamin D3 is an intermediate in the production of cholecalciferol (vitamin D3).</p>
    Formula:C27H44O
    Color and Shape:Solid
    Molecular weight:384.648
  • Streptolysin O

    CAS:
    <p>Streptolysin O: lyses cells, cardiotoxic, used for cell permeabilization, has active and inactive states.</p>
    Purity:98%
    Color and Shape:Solid
  • Trimipramine N-oxide

    CAS:
    <p>Trimipramine N-oxide, a trimipramine metabolite, inhibits hNAT, hSERT, hDAT, and hOCT1/2 with IC50s 11.7-27.4 nM; for depression/anxiety research.</p>
    Formula:C20H26N2O
    Color and Shape:Solid
    Molecular weight:310.43
  • Nuclease P1

    CAS:
    <p>Nuclease P1 cleaves single-stranded nucleic acids into 5'-mononucleotides; key in molecular biology, pharmaceuticals, and food.</p>
    Color and Shape:Solid
  • DSPE-PEG3000-R6H4


    <p>DSPE-PEG3000-R6H4 is a PEG compound composed of DSPE and the pH-responsive transmembrane peptide (R6H4). R6H4 is applicable for pH-responsive anticancer drug delivery. DSPE-PEG3000-R6H4 can be utilized for drug delivery purposes.</p>
    Color and Shape:Odour Solid
  • Desbutyl Lumefantrine

    CAS:
    <p>Desbutyl Lumefantrine is a metabolite of lumefantrine with antimalarial activity.</p>
    Formula:C26H24Cl3NO
    Purity:98%
    Color and Shape:Solid
    Molecular weight:472.83
  • trans-2-Hexadecenoyl-L-carnitine

    CAS:
    <p>trans-2-Hexadecenoyl-L-carnitine is an endogenous metabolite in urine[1].</p>
    Formula:C23H43NO4
    Color and Shape:Solid
    Molecular weight:397.59
  • IYPTNGYTR acetate


    <p>IYPTNGYTR acetate, a deamidation-sensitive peptide derived from Trastuzumab, is a suitable tool for monitoring the metabolism of Trastuzumab in vivo [1].</p>
    Color and Shape:Liquid
  • 5-NH2-Baicalein

    CAS:
    <p>5-NH2-Baicalein, an aminated metabolite of Baicalein, can be utilized for researching ammonia and ammonia-associated chronic diseases [1].</p>
    Formula:C15H11NO4
    Color and Shape:Solid
    Molecular weight:269.25
  • Metrizamide

    CAS:
    <p>Metrizamide is a nonionic radiopaque contrast agent.</p>
    Formula:C18H22I3N3O8
    Color and Shape:Solid
    Molecular weight:789.1
  • ent-Prostaglandin F2α

    CAS:
    <p>ent-Prostaglandin F2α is the enantiomer of PGF2α and is found in urine.</p>
    Formula:C20H34O5
    Color and Shape:Solid
    Molecular weight:354.487
  • Pyruvate kinase

    CAS:
    <p>Pyruvate kinase is a glycolytic enzyme that catalyzes the conversion of phosphoenolpyruvate and ADP to pyruvate and ATP [1] .</p>
    Color and Shape:Solid
  • Methyl gerfelin

    CAS:
    <p>Methyl gerfelin, a flavonoid, hinders osteoclast formation by targeting GLO1, SCP2, and SGTA proteins.</p>
    Formula:C16H16O6
    Color and Shape:Solid
    Molecular weight:304.29
  • DSM705

    CAS:
    <p>DSM705: Pyrrole-based, potent nanomolar Plasmodium DHODH inhibitor with strong antimalarial efficacy; spares mammalian DHODH.</p>
    Formula:C19H19F3N6O
    Color and Shape:Solid
    Molecular weight:404.397
  • HLF1-11

    CAS:
    <p>HLF1-11: human lactoferrin peptide, antimicrobial, inhibits MPO, steers monocytes to macrophages, boosts immunity.</p>
    Formula:C56H95N25O14S
    Color and Shape:Solid
    Molecular weight:1374.58
  • Anti-osteoporosis agent-10


    <p>Anti-osteoporosis agent-10 is an inhibitor of osteoporosis that suppresses the formation of osteoclasts with an IC50 of 0.042 μM. It also exhibits antagonistic activity towards PPARγ, with an EC50 value of 0.75 μM.</p>
    Color and Shape:Odour Solid
  • SHP2-IN-37


    <p>SHP2-IN-37 (compound C5) is a potent allosteric inhibitor selective for SHP2, with an IC50 of 0.023 μM. It exhibits antiproliferative effects on KYSE-520 and MV-411 cells, with IC50 values of 6.97 μM and 0.67 μM, respectively.</p>
    Formula:C19H22Cl2N4O2S
    Color and Shape:Solid
    Molecular weight:440.08405
  • Alphostatin

    CAS:
    <p>Alphostatin is an alkaline phosphatase inhibitor isolated from Bacillus megaterium.</p>
    Formula:C25H45N6O13P
    Color and Shape:Solid
    Molecular weight:668.638
  • Coproporphyrin I

    CAS:
    <p>Coproporphyrin I, an endogenous metabolite found in urine and blood, is utilized in researching liver disease and porphyria [1] [2] [3] [4].</p>
    Formula:C36H38N4O8
    Color and Shape:Solid
    Molecular weight:654.71
  • IP3RPEP6

    CAS:
    <p>IP3RPEP6 serves as a competitive inhibitor of IP3R. Its IC50 values for IP3R1, IP3R2, and IP3R3 are 9.0 μM, 3.9 μM, and 4.3 μM, respectively. This compound does not affect ryanodine receptors and Cx43 hemichannels, and it is capable of modulating intracellular calcium signaling.</p>
    Formula:C49H79N15O24
    Color and Shape:Solid
    Molecular weight:1262.24
  • Zifcasiran

    CAS:
    <p>Zifcasiran reduces HIF synthesis, has antitumor properties, useful in renal carcinoma studies.</p>
    Formula:C737H972F20N211O349P43S8
    Color and Shape:Solid
    Molecular weight:20339.13
  • Nε,Nε,Nε-Trimethyllysine chloride

    CAS:
    <p>Nε,Nε,Nε-Trimethyllysine chloride (Lys(Me)3-OH Chloride) is a methylated derivative of the amino acid lysine and a component of histone proteins.</p>
    Formula:C9H21ClN2O2
    Purity:99.83%
    Color and Shape:Solid
    Molecular weight:224.73
  • Canine Factor Xa


    <p>CanineFactor Xa is derived from purified Canine Factor X through activation by Russell's Viper Venom, after which the venom is removed.</p>
    Color and Shape:Odour Solid
  • Dihydrozeatin riboside

    CAS:
    <p>Dihydrozeatin riboside is a cytokinin that can be isolated from Phaseolus vulgaris L.</p>
    Formula:C15H23N5O5
    Color and Shape:Solid
    Molecular weight:353.37
  • Pepticinnamin E

    CAS:
    <p>Pepticinnamin E is a naturally occurring bisubstrate farnesyltransferase inhibitor.</p>
    Formula:C49H54ClN5O10
    Purity:98%
    Color and Shape:Solid
    Molecular weight:908.43
  • Carbonic anhydrase inhibitor 30


    <p>Carbonic anhydrase inhibitor30 (compound 17) is an inhibitor of carbonic anhydrase with Ki values of 2.13 μM for hCA I and 0.161 μM for hCA II[1].</p>
    Formula:C23H22FN3O5S
    Color and Shape:Solid
    Molecular weight:471.12642
  • (±)16-HDHA

    CAS:
    <p>(±)16-HDHA is an autoxidation product of docosahexaenoic acid (DHA) in vitro.</p>
    Formula:C22H32O3
    Color and Shape:Solid
    Molecular weight:344.495
  • Galactosylhydroxylysine

    CAS:
    <p>Galactosylhydroxylysine, a bone collagen breakdown product, is released during bone resorption and excreted in urine.</p>
    Formula:C12H24N2O8
    Color and Shape:Solid
    Molecular weight:324.33
  • 1-Heptadecanoyl-2-hydroxy-sn-glycero-3-phosphocholine

    CAS:
    <p>An endogenous blood metabolite, 1-heptadecanoyl-glycerophosphocholine, researches pregnancy/sepsis.</p>
    Formula:C25H52NO7P
    Color and Shape:Solid
    Molecular weight:509.66
  • Lipoxygenase

    CAS:
    <p>Lipoxygenase (LOX) is a dioxygenase that catalyzes the peroxidation of linoleic acid (LA) or arachidonic acid (AA) in the presence of molecular oxygen.</p>
    Color and Shape:Solid
  • hCA/Wnt/β-catenin-IN-1


    <p>hCA/Wnt/β-catenin-IN-1 (Compd 15) serves as an inhibitor with selective affinity for hCA isoforms II, IX, and XII, exhibiting K i values of 33.6, 24.1, and 6.8</p>
    Color and Shape:Odour Solid
  • Levothyroxine acyl glucuronide

    CAS:
    <p>Levothyroxine acyl glucuronide (Thyroxine Acyl-β-D-glucuronide), the acyl glucuronide formation of thyroxine (T4), an endogenous metabolite.</p>
    Formula:C21H19I4NO10
    Purity:98%
    Color and Shape:Solid
    Molecular weight:952.99
  • 5α-Hydroxy-6-keto cholesterol

    CAS:
    <p>Yakkasterone is a major metabolite of cholesterol formed during exposure of lung epithelial cells to ozone.</p>
    Formula:C27H46O3
    Color and Shape:Solid
    Molecular weight:418.662
  • 5-Formylcytosine

    CAS:
    <p>5-Formylcytosine (5FC) is a rare mammalian DNA base aiding in demethylation, altering helix structure, and affecting RNA polymerase II activity.</p>
    Formula:C5H5N3O2
    Color and Shape:Solid
    Molecular weight:139.11
  • Viridicatin

    CAS:
    <p>Viridicatin is a natural product for research related to life sciences. The catalog number is T38335 and the CAS number is 129-24-8.</p>
    Formula:C15H11NO2
    Color and Shape:Solid
    Molecular weight:237.25