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Metabolism

Metabolism

Metabolism inhibitors are compounds that interfere with metabolic pathways, altering the production and utilization of energy within cells. These inhibitors are used to study the regulation of metabolism, the role of metabolic pathways in diseases like cancer and diabetes, and to develop new therapeutic strategies. Metabolism inhibitors can target various enzymes and processes involved in glycolysis, fatty acid oxidation, and other metabolic functions. At CymitQuimica, we offer a wide range of high-quality metabolism inhibitors to support your research in biochemistry, metabolic disorders, and drug development.

Subcategories of "Metabolism"

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Found 8626 products of "Metabolism"

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  • SX29


    <p>SX29 is a non-competitive α-glucosidase inhibitor with oral activity, exhibiting an IC50 of 2.12 μM. It possesses hypoglycemic properties; oral administration of SX29 reduces blood glucose levels and enhances glucose tolerance in diabetic mice.</p>
    Color and Shape:Odour Solid
  • Relzomostat

    CAS:
    <p>Relzomostat inhibits MetAP2, with research potential for obesity and type 2 diabetes.</p>
    Formula:C24H36F2N2O5
    Color and Shape:Solid
    Molecular weight:470.558
  • DSPE-PEG1000-YIGSR


    <p>DSPE-PEG1000-YIGSR is a PEG compound consisting of DSPE and the biomimetic peptide YIGSR. YIGSR interacts with the 67 kDa laminin-binding protein (LBP) to enhance adhesion and spreading of various cell types, including endothelial cells, fibroblasts, and smooth muscle cells. DSPE-PEG1000-YIGSR is applicable for drug delivery.</p>
    Color and Shape:Odour Solid
  • FPI-1523 sodium

    CAS:
    <p>FPI-1523 sodium, avibactam derivative; β-lactamase inhibitor (Kd: CTX-M-15, 4nM; OXA-48, 34nM); PBP2 inhibitor (IC50, 3.2μM); strong antibacterial.</p>
    Formula:C9H13N4NaO7S
    Purity:99.42%
    Color and Shape:Solid
    Molecular weight:344.27
  • CP-LC-1422


    <p>CP-LC-1422 is a homocysteine-derived ionizable amino lipid known for its efficient RNA delivery capabilities, enabling high-level protein expression in vivo. When formulated in lipid nanoparticles (LNP) and administered intravenously, it demonstrates significant spleen-targeting properties without observed notable toxicity.</p>
    Formula:C51H97N3O8S3
    Color and Shape:Solid
    Molecular weight:975.64378
  • γ-glutamyltransferase

    CAS:
    <p>γ-glutamyltransferase (GGT) is an enzyme located on the outer surface of the cell membrane. It maintains physiological concentrations of intracellular glutathione and cellular defense against oxidative stress by cleaving extracellular glutathione and increasing the availability of amino acids. γ-glutamyltransferase can be utilized as a biomaterial or organic compound in life science-related research.</p>
    Color and Shape:Solid
  • Rostratin C

    CAS:
    <p>Rostratin C, a cytotoxic disulfide, exhibits in vitro cytotoxicity against human colon carcinoma (HCT-116), demonstrating an IC50 value of 0.76 μg/mL.</p>
    Formula:C20H24N2O8S2
    Color and Shape:Solid
    Molecular weight:484.54
  • Alismanol M

    CAS:
    <p>Alismanol M: FXR agonist, EC50 of 50.25 μM, from Alisma orientale, for cholestasis &amp; NASH research.</p>
    Formula:C30H48O6
    Color and Shape:Solid
    Molecular weight:504.7
  • 1,2-POPS sodium salt

    CAS:
    <p>1,2-POPS sodium salt is a lipid that can be used to synthesize artificial lipid membranes.</p>
    Formula:C40H75NNaO10P
    Color and Shape:Solid
    Molecular weight:783.99
  • Phosphate acetyltransferase

    CAS:
    <p>Phosphate acetyltransferase, an enzyme, reversibly transfers acetyl groups to CoA, aiding in acetate assimilation/dissimilation.</p>
    Color and Shape:Solid
  • Andrastin A

    CAS:
    <p>Andrastin A is a useful organic compound for research related to life sciences. The catalog number is T125574 and the CAS number is 174232-42-9.</p>
    Formula:C28H38O7
    Color and Shape:Solid
    Molecular weight:486.605
  • 15-LOX-1 inhibitor 1

    CAS:
    <p>9c(i472) blocks 15-LO-1 (IC50=0.19μM), lowers NF-κB in RAW-Blue cells, &amp; cuts Nos2/lipid peroxidation in RAW 264.7 at 0.2-5μM.</p>
    Formula:C22H21ClN2O4
    Color and Shape:Solid
    Molecular weight:412.87
  • Adefovir diphosphate 2TEA


    <p>Adefovir diphosphate 2TEA,a metabolite of Adefovir, an oral reverse transcriptase inhibitor with antiviral activity against herpes, hepatitis B, and HIV.</p>
    Formula:C20H43N7O7P2
    Purity:98.33%
    Color and Shape:Solid
    Molecular weight:555.55
  • 2,3-Indolobetulin

    CAS:
    <p>2,3-Indolobetulin is a pentacyclic triterpenoid and derivative of betulin .1It has been used in the synthesis of α-glucosidase inhibitors.</p>
    Formula:C36H51NO
    Color and Shape:Solid
    Molecular weight:513.81
  • IDO1/TDO-IN-7


    <p>IDO1/TDO-IN-7 (Compound 43b), an isochinoline derivative, functions as a potent dual inhibitor of IDO1/TDO with IC50 values of 0.31 μM and 0.08 μM, respectively. Demonstrating favorable pharmacokinetics and strong antitumor efficacy in the B16-F10 tumor model, this compound also exhibits low toxicity.</p>
    Color and Shape:Odour Solid
  • MSI-1436 lactate

    CAS:
    <p>MSI-1436 lactate is a selective, non-competitive the enzyme protein-tyrosine phosphatase 1B (PTB1B)inhibitor(IC50 of appr 1 μM)</p>
    Formula:C37H72N4O5SC3H6O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1000.17
  • Kijanimicin

    CAS:
    <p>Kijanimicin: antitumor, antibiotic with unique activity against Gram-positive, anaerobic bacteria, and malaria.</p>
    Formula:C67H100N2O24
    Color and Shape:Solid
    Molecular weight:1317.527
  • Spaglumic acid acetate


    <p>Spaglumic acid acetate (Isospaglumic acid acetate) is a neuropeptide found in millimolar concentrations in brain.</p>
    Formula:C13H20N2O10
    Purity:99.49%
    Color and Shape:Solid
    Molecular weight:364.31
  • Cytochrome P450 reductase

    CAS:
    <p>Cytochrome P450 reductase, a NADPH-cytochrome reductase, facilitates an optimal conformation of aromatase for substrate binding [1].</p>
    Color and Shape:Solid
  • Poly(4-vinylphenol)

    CAS:
    <p>Poly(4-vinylphenol) is an endogenous metabolite.</p>
    Formula:C10H17NO
    Purity:98%
    Color and Shape:Solid
    Molecular weight:167.252
  • PTPN22-IN-2


    <p>PTPN22-IN-2 (Compound 8b-19) is a PTPN22 inhibitor with an IC50 of 250 nM and is applicable in immunoregulation research.</p>
    Formula:C28H22ClNO6
    Color and Shape:Solid
    Molecular weight:503.93
  • WAY-615145

    CAS:
    WAY-615145 is a compound that activates glucokinase.
    Formula:C16H18N2OS
    Molecular weight:286.39
  • Mannose 6 phosphate

    CAS:
    Mannose 6-phosphate (M6P) features a type I integral membrane receptor.
    Formula:C6H13O9P
    Molecular weight:260.14
  • 10-FTHF

    CAS:
    <p>10-FTHF is a donor of formyl groups in anabolism used as a substrate in formyltransferase reactions, which is important in purine biosynthesis.</p>
    Formula:C20H23N7O7
    Color and Shape:Solid
    Molecular weight:473.44
  • Tpp-CAQK


    <p>Tpp-CAQK, a specially engineered mitochondrial compound, has been shown to improve phagocytosis of myelin debris by macrophages, reduce mitochondrial dysfunction and pro-inflammatory features, and enhance tissue repair and functional recovery in mice after spinal cord injury.</p>
    Formula:C40H54BrN6O7PS
    Color and Shape:Solid
    Molecular weight:873.84
  • (Z)-7-Dodecen-1-ol

    CAS:
    (Z)-7-Dodecen-1-ol counteracts the attractive properties of Z-7-dodecen-1-yl acetate.
    Formula:C12H24O
    Molecular weight:184.32
  • 1,2-Dipalmitoyl-sn-glycero-3-phosphoserine sodium salt

    CAS:
    <p>DPPS is a negatively charged diacyl-phospholipid used to create cationic vesicles and liposomes.</p>
    Formula:C38H73NNaO10P
    Purity:99.54%
    Color and Shape:Solid
    Molecular weight:757.95
  • DSPE-PEG1000-TAT


    <p>DSPE-PEG1000-TAT is a PEG compound composed of DSPE and the cell-penetrating peptide (TAT) peptide. It can be utilized for drug delivery.</p>
    Color and Shape:Odour Solid
  • D-Ribofuranose

    CAS:
    <p>D-Ribose, found in cerebrospinal fluid, is used to study Ribose 5 Phosphate and MCAD Deficiency.</p>
    Formula:C5H10O5
    Color and Shape:Solid
    Molecular weight:150.13
  • C18:1 Ceramide (d18:1/18:1(9Z))

    CAS:
    <p>C18:1 Ceramide (d18:1/18:1(9Z)) is a ceramide, and C18:1-Ceramide levels are elevated in overweight and insulin-resistant , advanced ovarian cancer.</p>
    Formula:C36H69NO3
    Purity:99.96%
    Color and Shape:Solid
    Molecular weight:563.94
  • (±)13(14)-DiHDPA

    CAS:
    <p>(±)13(14)-DiHDPA is a metabolite of docosahexaenoic acid that is produced via oxidation by cytochrome P450 epoxygenases.</p>
    Formula:C22H34O4
    Color and Shape:Solid
    Molecular weight:362.51
  • L-Lactate dehydrogenase

    CAS:
    <p>L-Lactate dehydrogenase is an enantiospecific redox enzyme reducing pyruvate to L-lactate using NADH.</p>
    Color and Shape:Solid
  • CBS-1114 HCl

    CAS:
    <p>CBS-1114 HCl: 5-lipoxygenase inhibitor, anti-inflammatory, improves heart function, reduces heart's fat.</p>
    Formula:C13H14ClN3
    Purity:99.36%
    Color and Shape:Soild
    Molecular weight:247.72
  • (R,S)-Carvedilol Glucuronide

    CAS:
    <p>(R,S)-Carvedilol glucuronide is a racemic mix, metabolized by UGT1A1, UGT2B4, and UGT2B7.</p>
    Formula:C30H34N2O10
    Color and Shape:Solid
    Molecular weight:582.606
  • hCA/Wnt/β-catenin-IN-1


    <p>hCA/Wnt/β-catenin-IN-1 (Compd 15) serves as an inhibitor with selective affinity for hCA isoforms II, IX, and XII, exhibiting K i values of 33.6, 24.1, and 6.8</p>
    Color and Shape:Odour Solid
  • KF-52


    <p>KF-52 is an inhibitor of phosphofructokinase-1 (PFK1), possessing an IC50 value of 2.1 μM. It significantly enhances the ratio of oxygen consumption rate (OCR) to extracellular acidification rate (ECAR).</p>
    Formula:C21H19F3N2O3
    Color and Shape:Solid
    Molecular weight:404.382
  • Pyruvate kinase

    CAS:
    <p>Pyruvate kinase is a glycolytic enzyme that catalyzes the conversion of phosphoenolpyruvate and ADP to pyruvate and ATP [1] .</p>
    Color and Shape:Solid
  • SGK1-IN-4

    CAS:
    <p>SGK1-IN-4 is a selective inhibitor of SGK1 and can be used in studies about osteoarthritis.</p>
    Formula:C23H21ClFN5O4S
    Purity:97.03%
    Color and Shape:Solid
    Molecular weight:517.96
  • Cy3-PEG-DSPE (MW 3400)


    <p>Cy3-PEG-DSPE (MW 3400) is a PEG phospholipid that incorporates Cy3 dye, utilized for labeling proteins/nucleic acids and in fluorescence microscopy. It can self-assemble in aqueous solutions to form micelles/lipid bilayers, and is employed in the creation of liposomes or nanoparticles for delivering nutrients such as mRNA or DNA vaccines.</p>
    Color and Shape:Solid
    Molecular weight:3400 (Average)
  • Maximiscin

    CAS:
    <p>Maximiscin, a metabolite derived from fungi, causes DNA damage and exhibits selective cytotoxic activity towards a specific subtype of triple-negative breast</p>
    Formula:C23H31NO8
    Color and Shape:Solid
    Molecular weight:449.49
  • LYP-IN-1

    CAS:
    <p>LYP-IN-1 is a potent, selective inhibitor of lymphoid-specific tyrosine phosphatase useful for studying autoimmune disorders and immune signaling.</p>
    Formula:C28H20ClNO6
    Purity:92.43%
    Color and Shape:Solid
    Molecular weight:501.92
  • 11-cis Retinal

    CAS:
    <p>11-cis Retinal, a chromophore, binds to opsin, activating rhodopsin for vision; light triggers it to start phototransduction.</p>
    Formula:C20H28O
    Color and Shape:Solid
    Molecular weight:284.443
  • LEI110

    CAS:
    <p>LEI110 inhibits PLA2G16 and HRASLS enzymes, Ki 20 nM, selectively targets related thiol hydrolases.</p>
    Formula:C25H23F3N2O3
    Purity:98.66% - 98.8%
    Color and Shape:Solid
    Molecular weight:456.46
  • Calcium Channel antagonist 3

    CAS:
    <p>Calcium Channel antagonist 3 is a voltage-gated calcium channel inhibitor (IC50 : 5-20 μM).</p>
    Formula:C23H26N2O4S
    Purity:>99.99%
    Color and Shape:Solid
    Molecular weight:426.53
  • (+)-Geodin

    CAS:
    <p>(+)-Geodin, a fungal metabolite, boosts fibrinolysis in BAECs (50-150 μM) and glucose uptake in rat adipocytes (1-100 μg/ml).</p>
    Formula:C17H12Cl2O7
    Color and Shape:Solid
    Molecular weight:399.18
  • DSPE-PEG1000-CREKA


    <p>DSPE-PEG1000-CREKA is a PEG compound composed of DSPE and the fibrin-targeting peptide (CREKA). The CREKA peptide has the capability to target tumor cells and tumor vasculature, exhibiting anti-tumor activity. Additionally, DSPE-PEG1000-CREKA can be utilized for drug delivery.</p>
    Color and Shape:Odour Solid
  • 4'-Methoxyisoagarotetrol

    CAS:
    <p>4'-Methoxyisoagarotetrol, a chromone derivative, exhibits moderate phosphodiesterase 3A (PDE3A) inhibitory activity with an IC50 value of 54 μM [1].</p>
    Formula:C18H20O7
    Color and Shape:Solid
    Molecular weight:348.35
  • Enterostatin(human,mouse,rat)

    CAS:
    <p>Enterostatin, human, mouse, rat is a pentapeptide that reduces fat intake.</p>
    Formula:C21H36N8O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:496.569
  • 5β-Androstan-3β-ol-17-one

    CAS:
    <p>5β-Androstan-3β-ol-17-one (3β-Etiocholanolone; 5β-Epiandrosterone), a 5β-reduced steroid and a significant metabolic derivative of dehydroepiandrosterone (DHEA</p>
    Formula:C19H30O2
    Color and Shape:Solid
    Molecular weight:290.44
  • Secalciferol

    CAS:
    <p>Secalciferol is a Vitamin D metabolite,Secalciferol is a possibly anti-inflammatory steroid which is involved in bone ossification.</p>
    Formula:C27H44O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:416.64