Metabolism
Metabolism inhibitors are compounds that interfere with metabolic pathways, altering the production and utilization of energy within cells. These inhibitors are used to study the regulation of metabolism, the role of metabolic pathways in diseases like cancer and diabetes, and to develop new therapeutic strategies. Metabolism inhibitors can target various enzymes and processes involved in glycolysis, fatty acid oxidation, and other metabolic functions. At CymitQuimica, we offer a wide range of high-quality metabolism inhibitors to support your research in biochemistry, metabolic disorders, and drug development.
Subcategories of "Metabolism"
- AhR(42 products)
- Aminopeptidase(76 products)
- CETP(20 products)
- Carbonic Anhydrase(196 products)
- Casein Kinase(139 products)
- DHFR(30 products)
- Decarboxylase(4 products)
- Dehydrogenase(302 products)
- FAAH(64 products)
- FXR(62 products)
- Factor Xa(87 products)
- Fatty Acid Synthase(37 products)
- Ferroptosis(227 products)
- GR(3 products)
- GSNOR(3 products)
- Glucokinase(56 products)
- HIF/HIF Prolyl-Hydroxylase(146 products)
- HMG-CoA Reductase(34 products)
- Hydroxylase(36 products)
- IDO(84 products)
- LDL(7 products)
- Lipase(107 products)
- Lipid(62 products)
- Lipoxygenase(133 products)
- MAO(85 products)
- MPO(2 products)
- NAMPT(40 products)
- P450(6 products)
- PAI-1(26 products)
- PDE(170 products)
- PED(1 products)
- PKM(17 products)
- PPAR(170 products)
- Phospholipase(85 products)
- ROR(47 products)
- Retinoid Receptor(18 products)
- SGK(10 products)
- Thioredoxin(12 products)
- Transferase(30 products)
- Transporter(43 products)
- UGT(4 products)
- Xanthine Oxidase (XO) Inhibitors(9 products)
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Found 9195 products of "Metabolism"
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Fmoc-Gly-Ser(psi(Me,Me)pro)-OH
CAS:Fmoc-Gly-Ser(psi(Me,Me)pro)-OH is a dipeptide.Formula:C23H24N2O6Color and Shape:SolidMolecular weight:424.45Tianeptine Metabolite MC5 sodium
CAS:Tianeptine metabolite MC5, an active derivative of the atypical antidepressant tianeptine produced through β-oxidation, exhibits selective G protein activationFormula:C19H20ClN2O4S·NaColor and Shape:SolidMolecular weight:430.88Glycyllysine
CAS:Glycyllysine is a dipeptide. It can be used to study the interactions of the lysine side chain with copper in Glycyl-L-lysine-copper(II) complex.Formula:C8H17N3O3Color and Shape:SolidMolecular weight:203.24SHP2-IN-37
SHP2-IN-37 (compound C5) is a potent allosteric inhibitor selective for SHP2, with an IC50 of 0.023 μM. It exhibits antiproliferative effects on KYSE-520 and MV-411 cells, with IC50 values of 6.97 μM and 0.67 μM, respectively.Formula:C19H22Cl2N4O2SColor and Shape:SolidMolecular weight:440.084053-Oxocholic acid
CAS:3-Oxocholic acid(3-Ketocholic acid) is the metabolite of bile acid and the main product of bile degradation by Clostridium perfringens in the intestine.3-Formula:C24H38O5Purity:99.44%Color and Shape:SolidMolecular weight:406.56Ref: TM-T19124
1mg44.00€5mg93.00€10mg126.00€25mg203.00€50mg303.00€100mg442.00€200mg642.00€1mL*10mM (DMSO)92.00€NDH-1 inhibitor-1
CAS:NDH-1 inhibitor-1 is an effective NDH-1 inhibitor, which can inhibit bovine SMP (mitochondrial granules), potato SMP and Escherichia coli, with pI50 values of <Formula:C20H19NO3Purity:99.91%Color and Shape:SolidMolecular weight:321.3711β-HSD1 inibitor 17
CAS:11β-HSD1 inibitor 17 is an inhibitor of 11β-hydroxysteroid dehydrogenase (11β-HSD1).Formula:C22H20F3N3O2SPurity:99.26% - 99.72%Color and Shape:SoildMolecular weight:447.47Dimethylaminomicheliolide HCl
CAS:Dimethylaminomicheliolide HCl has potential anti-inflammatory and anti-tumor activity and inhibits the proliferation of glioblastoma cells by targeting pyruvateFormula:C17H28ClNO3Purity:99.91%Color and Shape:SoildMolecular weight:329.86N-Desbutyl Dronedarone-d7 HCl
N-Desbutyl Dronedarone-d7 HCl is the deuterium-labelled isomer of N-Desbutyl Dronedarone HCl, used for isotope tracing. N-Desbutyl Dronedarone is a metabolite of the antiarrhythmic drug Dronedarone.Formula:C27H30D7ClN2O5SColor and Shape:SolidMolecular weight:544.15Acesulfame
CAS:Acesulfame inhibits CA9/12 and can be used to study inflammation-related diseases.Formula:C4H5NO4SColor and Shape:SolidMolecular weight:163.15VH4127
VH4127 is a cyclic peptide designed to target low-density lipoprotein receptors (LDLR) with a KD of 18 nM for hLDLR. Incorporating non-natural amino acid residues, VH4127 binds specifically to epidermal growth factor (EGF) LDLR homologous domains in both rodents and humans.Formula:C41H73N15O9S4Color and Shape:SolidMolecular weight:1048.37D-3
CAS:D-3, a phosphorpeptide, is an efficient, simple, and specific iPSC-eliminating agent.Formula:C48H47N4O10PColor and Shape:SolidMolecular weight:870.896PKM2-IN-10
PKM2-IN-10 is a PKM2 inhibitor. It effectively suppresses the proliferation of A549 and HCC1833 cell lines with IC50 values of 3.36 μM and 9.20 μM, respectively. PKM2-IN-10 demonstrates antitumor activity in human non-small cell lung cancer (NSCLC) and mouse lung adenocarcinoma models. It is applicable for research in lung cancer.Formula:C21H15F4N5Color and Shape:SolidMolecular weight:413.126361-(2-Quinoxalinyl)-1,2,3,4-butanetetrol
CAS:1-(2-Quinoxalinyl)-1,2,3,4-butanetetrol is a quinoxaline derivative and endogenous metabolite applicable to biochemical experiments and drug synthesis research.Formula:C12H14N2O4Purity:99.49%Color and Shape:SolidMolecular weight:250.25Lysylcysteine TFA
Lysylcysteine (L-Lysyl-L-cysteine)TFA is a dipeptide composed of lysine and cysteine.Formula:C13H21F6N3O7SColor and Shape:SolidMolecular weight:477.10044Prolylglutamic acid
CAS:Prolylglutamic acid (H-Pro-Glu-OH) is a proline-glutamic acid dipeptide and endogenous metabolite, targeting the LipY lipase of pathogenic mycobacteria.Formula:C10H16N2O5Color and Shape:SolidMolecular weight:244.24IDO1/TDO-IN-8
IDO1/TDO-IN-8 (Compound CZ-17) is a dual IDO1 and TDO inhibitor capable of crossing the blood-brain barrier, with EC50 values of 0.33 μM and 1.78 μM, respectively. It modulates the kynurenine pathway of tryptophan metabolism, reducing the kynurenine/tryptophan ratio. IDO1/TDO-IN-8 has neuroprotective effects, alleviating motor dysfunction and improving depressive behavior, making it relevant for research into Parkinson's disease with comorbid depression.Formula:C17H14N2SColor and Shape:SolidMolecular weight:278.37Casein Kinase 2 Substrate Peptide
CAS:CK2 Substrate Peptide, C-terminus linked to EDANS, used for CK2 activity assays.Formula:C45H73N19O24Color and Shape:SolidMolecular weight:1264.17Casein kinase 1δ-IN-9
CAS:Casein kinase 1δ-IN-9 is a Quinone reductase 2 inhibitor with IC50 of 0.6μM.
Formula:C15H12ClN3Purity:99.93%Color and Shape:SolidMolecular weight:269.7311R-CaN-AID
CAS:11R-CaN-AID is a potent, cell-permeant inhibitor of calcineurin [1] [2].Formula:C135H248N70O34S2Color and Shape:SolidMolecular weight:3459.991-Methylisatin
CAS:Compound 2058-74-4, with CAS No. 2058-74-4, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound 2058-74-4 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Formula:C9H7NO2Purity:99.71%Color and Shape:Orange To Brownish Crystalline PowderMolecular weight:161.16UG-480
UG-480 is a Gemini analog that effectively stabilizes the active VDR conformation. It exhibits antiproliferative effects in estrogen receptor-positive MCF-7 breast adenocarcinoma cells and is utilized in cancer research.Color and Shape:Odour SolidDPTIP
CAS:DPTIP is an effective inhibitor of neutral sphingomyelinase 2 with an IC50 value of 30 nM.Formula:C21H18N2O3SPurity:99.88%Color and Shape:SolidMolecular weight:378.44Ref: TM-T60043
1mg48.00€2mg63.00€5mg96.00€10mg153.00€25mg298.00€50mg487.00€100mg710.00€1mL*10mM (DMSO)96.00€DSPE-PEG-Maleimide ammonium (MW 2000)
DSPE-PEG-Maleimide (ammonium) (MW 2000) is a compound containing DSPE phospholipids and maleimide, designed for the preparation of nanoscale lipid carriers. It is applicable in the study of drug delivery systems.Color and Shape:Odour SolidN1,N12-Diacetylspermine dihydrochloride
CAS:Diacetylspermine 2HCl, a diacetylated Spermine, is a cancer biomarker linked to the disease's up-regulation.
Formula:C14H32Cl2N4O2Purity:98%Color and Shape:SolidMolecular weight:359.34Nucleocidin
CAS:Nucleocidin, an antitrypanosomal antibiotic, inhibits the transfer of labeled amino acids from S-RNA to protein.Formula:C10H13FN6O6SPurity:98%Color and Shape:SolidMolecular weight:364.31D-Threonine
CAS:D-Threonine (H-D-Thr-OH) is one of the metabolites of Saccharomyces cerevisiae.
Formula:C4H9NO3Purity:≥98%Color and Shape:SolidMolecular weight:119.12FZQ-21
FZQ-21 (Compound 70P) is an inhibitor of the water-soluble epoxide hydrolase (sEH), with an IC50 value of 4 nM. The IC50 for inhibiting human sEH is 1.5 nM, which is comparable to that of EC5026 (1.7 nM). FZQ-21 is utilized in sepsis research.
Formula:C28H30N4O3Molecular weight:470.231791,1,3-Tribromoacetone
CAS:1,1,3-Tribromoacetone (1,1,3-tribromo-2-propanone) is an impurity of methotrexate.Formula:C3H3Br3OPurity:98%Color and Shape:SolidMolecular weight:294.77FABP4-IN-3
FABP4-IN-3 (Compound C3) is a highly selective inhibitor of FABP4, with an inhibition constant (Ki) of 25 ± 3 nM for FABP4 and a Ki of 15.03 μM for FABP3, showcasing a selectivity factor of 601 times over FABP3. It also demonstrates metabolic stability and potent anti-inflammatory activity in cells, making it a promising candidate for research in metabolic disorders, cardiac dysfunction, and inflammation-related diseases.
Formula:C20H16ClNO2Molecular weight:337.08696Photo-DL-lysine
Photo-DL-lysine is a photo-reactive amino acid based on DL-lysine used to capture proteins that are post-translationally modified by lysine binding.Formula:C6H12N4O2Molecular weight:172.09603α-Glucosidase-IN-48
α-Glucosidase-IN-48 (compound 9) is a potent inhibitor of α-Glucosidase, with an IC50 of 1.30 μM.Formula:C15H9Cl2N5O3SMolecular weight:408.98032Transketolase-IN-5
Transketolase-IN-5 (compound 6ba) is an inhibitor of transketolase. It exhibits herbicidal activity against Amaranthus retroflexus, Setaria viridis, and Digitaria sanguinalis.Formula:C20H24ClN5OMolecular weight:385.16694α-Glucosidase-IN-44
α-Glucosidase-IN-44 (compound IT4) is an α-glucosidase inhibitor with an IC50 value of 2.35 μM. This compound is orally active and has the ability to reduce fasting blood glucose levels in diabetic mice.Formula:C23H21N3O3SMolecular weight:419.13036Xanthine oxidase-IN-13
Xanthine oxidase-IN-13 (Compound 10) is a selective inhibitor of xanthine oxidase, with an IC50 of 149.56 μM for bovine xanthine oxidase. It is utilized in the study of inflammatory arthritis.Formula:C14H13NOMolecular weight:211.09971Hexokinase II VDAC binding domain peptide, cell-permeable
HexokinaseIIVDACbinding domain peptide (Hxk2VBD peptide) is a cell-permeable peptide derived from the hexokinase II VDAC binding domain. This peptide inhibits the mitochondrial localization of hexokinase 2 (HXK2) and also suppresses neurotrophic factor-induced axon growth.Formula:C188H291N53O40S2Molecular weight:3995.18073α-Amylase/α-Glucosidase-IN-14
α-Amylase/α-Glucosidase-IN-14 is an orally bioactive inhibitor of α-amylase and α-glucosidase, with IC50 values of 45.53 μM and 27.73 μM, respectively.Formula:C24H19FN4O2SMolecular weight:446.12128α-Amylase/α-Glucosidase-IN-9
α-Amylase/α-Glucosidase-IN-9 (compound 5h) is a dual inhibitor of α-amylase (IC50= 16.4 μM) and α-glucosidase (IC50= 31.6 μM).Formula:C20H16ClN5O4Molecular weight:425.08908α-Amylase/α-Glucosidase-IN-15
α-Amylase/α-Glucosidase-IN-15 (compound 6C) is an orally active inhibitor of α-glucosidase (α-Glucosidase) and α-amylase (α-amylase), with IC50 values of 21 μM and 61 μM, respectively.Formula:C26H24N4O3SMolecular weight:472.15691α-Glucosidase-IN-65
α-Glucosidase-IN-65 (compound 5) is a Schiff base derivative of 3,4-dihydroxyphenylacetic acid. It acts as a potent α-glucosidase inhibitor with an IC50 of 12.84 μM.Formula:C15H14N2O6Molecular weight:318.08519α-Glucosidase-IN-50
α-Glucosidase-IN-50 (compound 8) acts as an inhibitor of α-Glucosidase.Formula:C33H28Cl4N6O6SMolecular weight:776.05451FXIIa-IN-4
FXIIa-IN-4 (compound 22) is a potent and selective human FXIIa inhibitor, exhibiting IC50 values of 0.032 μM for FXIIa, 0.30 μM for thrombin, and >50 μM for FXIa. It is utilized in anticoagulant research.Formula:C11H9FN4O3Molecular weight:264.06587LTA4H-IN-4
LTA4H-IN-4 (compound 3) is an orally active inhibitor of LTA4H. It exhibits an IC50 value of 156 μM against hERG and is applicable for inflammation-related research.Antibacterial agent 218
Antibacterialagent 218 (compound d28) is an orally active inhibitor of sterol 24-C-methyltransferase with an IC50 value of 0.273 μM. It also displays antifungal activity against Candida albicans SC5314, with an IC50 of 0.25 μg/mL.Formula:C30H24N4OSMolecular weight:488.16708α-Glucosidase-IN-49
α-Glucosidase-IN-49 (compound C23) is a potent inhibitor of α-Glucosidase, with an IC50 of 0.52 μM. This compound exhibits oral bioactivity, effectively lowering blood glucose levels and enhancing glucose tolerance in mice.Formula:C21H13F3N4O3S3Molecular weight:522.01019hCAIX/XII-IN-11
hCAIX/XII-IN-11 (Compound 6c) is an inhibitor of hCA IX and hCA XII, exhibiting Ki values of 0.7 μM for both isoforms. This compound is applicable in cancer research.Formula:C13H10FN3O4Molecular weight:291.06553IDO1-IN-24
IDO1-IN-24 (compound 2c) inhibits the production of IDO1 during cell assays, with an IC50 value of 17 μM.Formula:C18H22N2O4Molecular weight:330.15796AChE/BChE-IN-17
AChE/BChE-IN-17 (compound 8m) is a potent inhibitor of AChE and BChE, displaying IC50 values of 125.06 nM and 119.68 nM, respectively. Additionally, AChE/BChE-IN-17 inhibits α-glucosidase, with an IC50 of 41050 nM.Formula:C28H25N3O4Molecular weight:467.18451Human Factor VIIa
HumanFactor VIIa is a vitamin K-dependent serine protease involved in the blood coagulation process. It has the ability to activate coagulation factor X, which in turn converts prothrombin into thrombin, leading to the transformation of fibrinogen into fibrin and resulting in the formation of blood clots. HumanFactor VIIa holds potential for improving hemophilia.α-Amylase/α-Glucosidase-IN-11
α-Amylase/α-Glucosidase-IN-11 (Compound 5d) is an isoxazoline-indigo hybrid with notable antidiabetic properties. It acts as a competitive inhibitor of the key digestive enzymes α-amylase (IC50 = 30.39 μM) and α-glucosidase (IC50 = 65.1 μM). Additionally, it does not penetrate the blood-brain barrier.Formula:C33H40ClN5O5Molecular weight:621.2718
