
Metabolism
Metabolism inhibitors are compounds that interfere with metabolic pathways, altering the production and utilization of energy within cells. These inhibitors are used to study the regulation of metabolism, the role of metabolic pathways in diseases like cancer and diabetes, and to develop new therapeutic strategies. Metabolism inhibitors can target various enzymes and processes involved in glycolysis, fatty acid oxidation, and other metabolic functions. At CymitQuimica, we offer a wide range of high-quality metabolism inhibitors to support your research in biochemistry, metabolic disorders, and drug development.
Subcategories of "Metabolism"
- AhR(42 products)
- Aminopeptidase(76 products)
- CETP(20 products)
- Carbonic Anhydrase(196 products)
- Casein Kinase(139 products)
- DHFR(30 products)
- Decarboxylase(4 products)
- Dehydrogenase(302 products)
- FAAH(64 products)
- FXR(62 products)
- Factor Xa(87 products)
- Fatty Acid Synthase(37 products)
- Ferroptosis(227 products)
- GR(3 products)
- GSNOR(3 products)
- Glucokinase(56 products)
- HIF/HIF Prolyl-Hydroxylase(146 products)
- HMG-CoA Reductase(34 products)
- Hydroxylase(36 products)
- IDO(84 products)
- LDL(7 products)
- Lipase(107 products)
- Lipid(62 products)
- Lipoxygenase(133 products)
- MAO(85 products)
- MPO(2 products)
- NAMPT(40 products)
- P450(6 products)
- PAI-1(26 products)
- PDE(170 products)
- PED(1 products)
- PKM(17 products)
- PPAR(170 products)
- Phospholipase(85 products)
- ROR(47 products)
- Retinoid Receptor(20 products)
- SGK(10 products)
- Thioredoxin(12 products)
- Transferase(30 products)
- Transporter(43 products)
- UGT(4 products)
- Xanthine Oxidase (XO) Inhibitors(9 products)
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Found 9198 products of "Metabolism"
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4-Hydroxyphenylbutazone
CAS:4-Hydroxyphenylbutazone, a Phenylbutazone metabolite, enhances PHS's peroxidase activity as an NSAID.Formula:C19H20N2O3Color and Shape:SolidMolecular weight:324.38PDE5-IN-10
PDE5-IN-10 (compound 4b), a potent phosphodiesterase type 5 (PDE5) inhibitor, exhibits an effective half-maximal inhibitory concentration (IC50) of 20 nM,Formula:C21H20N4O2Color and Shape:SolidMolecular weight:360.411-Palmitoyl-2-Oleoyl-3-Arachidonoyl-rac-glycerol
CAS:Triacylglycerol with palmitic, oleic, arachidonic acids at sn-1, sn-2, sn-3; found in rat retina lipid extracts.Formula:C57H100O6Color and Shape:SolidMolecular weight:881.421Mebeverine acid
CAS:Mebeverine acid (Mebeverine metabolite Mebeverine acid) is a secondary metabolite of Mebeverine and can be used as a marker of oral exposure to Mebeverine.Formula:C16H25NO3Purity:99.66%Color and Shape:SolidMolecular weight:279.37Trifluoperazine N-Glucuronide
CAS:Trifluoperazine N-Glucuronide is a metabolite of Trifluoperazine with antidepressant and antipsychotic activity.Formula:C27H32F3N3O6SColor and Shape:SolidMolecular weight:583.62Pi-Methylimidazoleacetic acid
CAS:Pi-Methylimidazoleacetic acid is a potential neurotoxin.Formula:C6H8N2O2Purity:98%Color and Shape:SolidMolecular weight:140.14Diphlorethohydroxycarmalol
CAS:Diphlorethohydroxycarmalol is a useful organic compound for research related to life sciences and the catalog number is T125953.Formula:C24H16O13Color and Shape:SolidMolecular weight:512.3794'-Methoxyisoagarotetrol
CAS:4'-Methoxyisoagarotetrol, a chromone derivative, exhibits moderate phosphodiesterase 3A (PDE3A) inhibitory activity with an IC50 value of 54 μM [1].Formula:C18H20O7Color and Shape:SolidMolecular weight:348.35Irsogladine maleate
CAS:Compound PDK0375, with CAS No. 84504-69-8, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0375 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Formula:C9H7Cl2N5Color and Shape:SolidMolecular weight:256.09Cyclopenol
CAS:Cyclopenol is a natural product that can be used as a reference standard. The CAS number of Cyclopenol is 20007-85-6.Formula:C17H14N2O4Color and Shape:SolidMolecular weight:310.3093-Oxo-7-hydroxychol-4-enoic acid
CAS:3-Oxo-7-hydroxychol-4-enoic acid, a body metabolite, may signal bad liver disease prognosis.Formula:C24H36O4Color and Shape:SolidMolecular weight:388.54(S)-3,4-Dihydroxybutyric acid
CAS:(S)-3,4-Dihydroxybutyric acid is a human urinary metabolite.Formula:C4H8O4Purity:98%Color and Shape:SolidMolecular weight:120.1CP-610431
CAS:CP-610431 inhibits ACC1/ACC2 (nonselective) with ~50 nM IC50, potentially aiding metabolic syndrome research.Formula:C30H37N3O2Color and Shape:SolidMolecular weight:471.6452-Hydroxyquinoline
CAS:Compound PDK0291, with CAS No. 59-31-4, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0291 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Formula:C9H7NOColor and Shape:White SolidMolecular weight:145.15Phosphodiesterase
CAS:PDE enzyme hydrolyzes cyclic nucleotides, regulates signal transduction, and varies in type (PDE1-PDE11) with disease research potential.Color and Shape:SolidHydroxycotinine
CAS:Hydroxycotinine is the main nicotine metabolite detected in smokers' urine.Formula:C10H12N2O2Purity:98%Color and Shape:SolidMolecular weight:192.218THX6
THX6 is an activator of human mitochondrial protease ClpP, with an EC50 of 1.18 μM. It displays cytotoxicity in ONC201-resistant SU-DIPG-VI cells, with an IC50 of 0.13 μM. THX6 inhibits the expression of mitochondria-related proteins (such as parkin, TFAM, NRF1, SDHA), leading to impaired mitochondrial function. Additionally, THX6 affects cell membrane lipid metabolism and exhibits antitumor potential.Formula:C22H18Cl2N4O2Color and Shape:SolidMolecular weight:441.31Seco Rapamycin sodium salt
CAS:Seco Rapamycin sodium salt is a ring-opened product of Rapamycin.Formula:C51H79NNaO13Purity:98%Color and Shape:SolidMolecular weight:937.177cis-Vitamin K1
CAS:Cis-Vitamin K1 is an endogenous metabolite of Vitamin K [1] .Formula:C31H46O2Color and Shape:SolidMolecular weight:450.70Vitamin K1 2,3-epoxide
CAS:Vitamin K1 2,3-epoxide (Phylloquinone oxide) is reduced to vitamin k and is involved in the vitamin k cycle.Formula:C31H46O3Purity:98% - 98.05%Color and Shape:SolidMolecular weight:466.70NU227326
CAS:NU227326 is a PROTAC degrader of indoleamine 2,3-dioxygenase 1 (IDO1) with a DC50 value of 4.5 nM. It effectively degrades IDO1 in U87 and GBM43 cells, with DC50 values of 7.1 nM and 11.8 nM, respectively. NU227326 exhibits favorable pharmacokinetic properties, with a plasma half-life of 5.7 hours and a brain tissue half-life of 11.8 hours. (Pink: ligand for target protein IDO1 ligand-1; Black: linker; Blue: ligand for E3 ligase Cereblon).Formula:C53H61FN8O7Color and Shape:SolidMolecular weight:941.099L-Lactate dehydrogenase
CAS:L-Lactate dehydrogenase is an enantiospecific redox enzyme reducing pyruvate to L-lactate using NADH.Color and Shape:SolidMSI-1436 lactate
CAS:MSI-1436 lactate is a selective, non-competitive the enzyme protein-tyrosine phosphatase 1B (PTB1B)inhibitor(IC50 of appr 1 μM)Formula:C37H72N4O5SC3H6O3Purity:98%Color and Shape:SolidMolecular weight:1000.17Tauro-α-muricholic Acid (sodium salt)
CAS:Tauro-α-muricholic acid (TαMCA) is an antagonist of the farnesoid X receptor (FXR; IC50 = 28 μM) and a taurine-conjugated form of the murine-specific primaryFormula:C26H44NNaO7SColor and Shape:SolidMolecular weight:537.69α-Hydroxytamoxifen
CAS:α-Hydroxytamoxifen is a metabolite of tamoxifen. It reacts with DNA and causes the formation of DNA adducts.Formula:C26H29NO2Purity:98%Color and Shape:SolidMolecular weight:387.51Methylcardol triene
CAS:Methylcardol triene, a phenolic compound present in cashew nut shell liquid, demonstrates α-glucosidase inhibition (IC50= 39.6 µM) and exhibits schistosomicidal properties by eliminating 100% of adult S. mansoni worms within 24 hours at 100 and 200 µM concentrations. Moreover, it serves as a precursor for synthesizing mono- and bis-benzoxazines.Formula:C22H32O2Color and Shape:SolidMolecular weight:328.496Carboxyaminoimidazole ribotide
CAS:CAIR, an E. coli metabolite, helps identify its PurE active site and aids in fungal purine synthesis.Formula:C9H14N3O9PColor and Shape:SolidMolecular weight:339.2hCA/VEGFR-2-IN-4
hCA/VEGFR-2-IN-4 (compound 15b), an indolinylbenzenesulfonamide, serves as a potential dual inhibitor targeting cancer-related human carbonic anhydrases hCA IX/Formula:C22H23FN6O5SPurity:98%Color and Shape:SolidMolecular weight:502.52DSPE-PEG1000-WYRGRL
DSPE-PEG1000-WYRGRL consists of DSPE and a cartilage-targeting peptide (WYRGRL) as a PEG compound. WYRGRL is a type II collagen-targeting peptide that can bind to type II collagen α1. DSPE-PEG1000-WYRGRL is suitable for drug delivery applications.Color and Shape:Odour SolidBiotin-Vitamin B12
Biotin-Vitamin B12, a biotinylated form, is crucial for brain, nervous system function, and blood formation.Formula:C73H102CoN16O16PSColor and Shape:SolidMolecular weight:1581.66DSPE-PEG1000-CGKRK
DSPE-PEG1000-CGKRK is a PEG compound composed of DSPE and the cell-penetrating peptide (CGKRK). It is utilized for drug delivery.Color and Shape:Odour SolidN4-Acetylcytidine triphosphate
CAS:N4-Acetylcytidine triphosphate is efficiently used as a substrate in T7 Polymerase-catalyzed in vitro transcription .Formula:C11H18N3O15P3Purity:98%Color and Shape:SolidMolecular weight:525.19Echinocandin B
CAS:Echinocandin B: a cyclic hexapeptide from A. nidulans, inhibits fungal cell wall synthesis by blocking beta-1,3-glucan.Formula:C52H81N7O16Color and Shape:SolidMolecular weight:1060.24GS-493
CAS:GS-493: Specific SHP2 inhibitor, very potent (IC50=71 nM), 29x affinity vs. SHP1, 45x vs. PTP1B; hinders cancer cell growth/movement.Formula:C21H14N6O8SColor and Shape:SolidMolecular weight:510.44HIF-PHD-IN-4
HIF-PHD-IN-4 (Compound 13) is an orally active PHD2 inhibitor with an IC50 of 100 nM. At a dose of 2 mg/kg, it effectively enhances G-CSF-induced mobilization of hematopoietic stem cells in mice. HIF-PHD-IN-4 is suitable for research in the oncology field.Color and Shape:Odour SolidPicornain 3C
CAS:Picornain 3C, a protease in picornaviruses, cleaves Gln-Gly bonds in poliovirus polyproteins and similar sites in others.Color and Shape:Solid(±)13(14)-DiHDPA
CAS:(±)13(14)-DiHDPA is a metabolite of docosahexaenoic acid that is produced via oxidation by cytochrome P450 epoxygenases.Formula:C22H34O4Color and Shape:SolidMolecular weight:362.51H-Ile-Pro-Pro-OH
CAS:H-Ile-Pro-Pro-OH, a milk-derived peptide, inhibits angiotensin-converting enzyme (ACE)[1] with an IC50 of 5 μM.Formula:C16H27N3O4Purity:98%Color and Shape:SolidMolecular weight:325.4DSPE-PEG2000-NYZL1
DSPE-PEG2000-NYZL1 is a PEG compound composed of DSPE and NYZL1. NYZL1 has the ability to specifically bind to bladder cancer tissues and cells. DSPE-PEG2000-NYZL1 is suitable for drug delivery applications.Color and Shape:Odour SolidCAIX/CAXII-IN-4
CAIX/CAXII-IN-4 (Compound 7h) is an inhibitor of carbonic anhydrase (CA) that binds to CAIX, CA XII, and CAII with Ki values of 1.324 μM, 0.435 μM, and 3.035 μM, respectively. This compound exhibits broad-spectrum anti-tumor activity and inhibits the proliferation of central nervous system tumor cells U251, with a GI50 of 0.361 μM.Formula:C23H21N5O3SColor and Shape:SolidMolecular weight:447.51Rubratoxin A
CAS:Rubratoxin A is a classical mycotoxin used as a PP2A-specific inhibitor.Formula:C26H32O11Purity:98%Color and Shape:SolidMolecular weight:520.53118:0,18:1 PS sodium
CAS:18:0,18:1 PS sodium, a lipid found in synaptic vesicles and cholesterol, serves a role in metabolic research [1].Formula:C42H79NNaO10PColor and Shape:SolidMolecular weight:812.04Mersalyl
CAS:Mersalyl is an organic mercurial diuretic.Formula:C13H16HgNNaO6Color and Shape:SolidMolecular weight:505.854Alphostatin
CAS:Alphostatin is an alkaline phosphatase inhibitor isolated from Bacillus megaterium.
Formula:C25H45N6O13PColor and Shape:SolidMolecular weight:668.638Cho-Arg (trifluoroacetate salt)
CAS:Cho-Arg is a cholesterol-based cationic lipid that complexes with DNA, aids transfection, and is cytotoxic at 88.5 μg/ml IC50.Formula:C43H71F6N5O7Color and Shape:SolidMolecular weight:884.059Ruthenoleuton
Ruthenoleuton is a 5-lipoxygenase (5-LOX) inhibitor with an IC50 of 3.49 μM and a Ki of 0.80 μM. It possesses antioxidant properties and is applicable in research on inflammatory diseases.Formula:C13H16N2O2RuColor and Shape:SolidMolecular weight:333.35Tetracosanoyl-sulfatide
CAS:C24 3'-sulfo Galactosylceramide is a key myelin sulfatide, high in leukodystrophy patients, non-immunogenic compared to C24:1 variant.Formula:C48H93NO11SColor and Shape:SolidMolecular weight:892.32Palitantin
CAS:Palitantin is a useful organic compound for research related to life sciences. The catalog number is T125757 and the CAS number is 15265-28-8.Formula:C14H22O4Color and Shape:SolidMolecular weight:254.326N1-Acetylspermine
CAS:N1-Acetylspermine, an endogenous metabolite found in urine, has applications in leukemia research [1] [2].
Formula:C12H28N4OColor and Shape:SolidMolecular weight:244.38Leuhistin
CAS:Leuhistin is an aminopeptidases N inhibitor isolated from Bacillus laterosporus BMI156-14F1.Formula:C11H19N3O3Purity:98%Color and Shape:White To Off-White SolidMolecular weight:241.29

