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Metabolism

Metabolism

Metabolism inhibitors are compounds that interfere with metabolic pathways, altering the production and utilization of energy within cells. These inhibitors are used to study the regulation of metabolism, the role of metabolic pathways in diseases like cancer and diabetes, and to develop new therapeutic strategies. Metabolism inhibitors can target various enzymes and processes involved in glycolysis, fatty acid oxidation, and other metabolic functions. At CymitQuimica, we offer a wide range of high-quality metabolism inhibitors to support your research in biochemistry, metabolic disorders, and drug development.

Subcategories of "Metabolism"

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Found 8597 products of "Metabolism"

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  • Carbonic anhydrase

    CAS:
    <p>Carbonic anhydrase, a zinc enzyme in all life forms, converts CO2 to bicarbonate; studied for cancer, glaucoma, obesity, epilepsy.</p>
    Color and Shape:Solid
  • Relzomostat

    CAS:
    <p>Relzomostat inhibits MetAP2, with research potential for obesity and type 2 diabetes.</p>
    Formula:C24H36F2N2O5
    Color and Shape:Solid
    Molecular weight:470.558
  • Mitochondrial respiration-IN-3


    <p>Mitochondrial respiration-IN-3, a cell-permeable fluorine derivative of Dalfopristin, inhibits glioblastoma stem cell translation for cancer research.</p>
    Formula:C35H51FN4O7S
    Color and Shape:Solid
    Molecular weight:690.87
  • Ercalcidiol

    CAS:
    <p>Ercalcidiol is a metabolite of vitamin D2 and can be used in monitoring vitamin D therapy.</p>
    Formula:C28H44O2
    Purity:99.62%
    Color and Shape:Solid
    Molecular weight:412.65
  • α-Glucosidase-IN-50


    <p>α-Glucosidase-IN-50 (compound 8) acts as an inhibitor of α-Glucosidase.</p>
    Formula:C33H28Cl4N6O6S
    Molecular weight:776.05451
  • Bipolamine G

    CAS:
    <p>Bipolamine G is an antibacterial polyketide alkaloid [1] .</p>
    Formula:C21H28N2O4
    Color and Shape:Solid
    Molecular weight:372.46
  • Carboxypeptidase B

    CAS:
    <p>Carboxypeptidase B degrades peptides from C-terminal, freeing amino acids, and targets basic residues.</p>
    Color and Shape:Solid
  • 1-Stearoyl-2-Adrenoyl-sn-glycero-3-PE

    CAS:
    <p>Phospholipid with stearic acid at sn-1, adrenic acid at sn-2; less in older human hippocampal mitochondria.</p>
    Formula:C45H82NO8P
    Color and Shape:Solid
    Molecular weight:796.124
  • CA Ⅱ-IN-1


    <p>CAⅡ-IN-1 (compound 2i) is an inhibitor of the CA Ⅱ isozyme, exhibiting an IC50 of 0.44 µM. This compound is utilized in metabolic research.</p>
    Formula:C18H19NO6S
    Color and Shape:Solid
    Molecular weight:377.41
  • RPR132595A hydrochloride


    <p>RPR132595A (NPC) hydrochloride, an active metabolite of CPT-11, is produced via cytochrome P-450 3A4 (CYP3A4) metabolism and is ultimately eliminated via</p>
    Formula:C28H31ClN4O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:555.02
  • O-desmethyl Mebeverine acid

    CAS:
    <p>O-desmethyl Mebeverine acid is a metabolite of Mebeverine.</p>
    Formula:C15H23NO3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:265.35
  • NAMPT degrader-3


    <p>NAMPT Degrader-3 (compound C5) is a NAMPT degrader that functions through a VHL- and proteasome-dependent mechanism.</p>
    Formula:C56H74N8O7S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1003.3
  • GPX4-IN-16


    <p>GPX4-IN-16 ((R)-9i) is a potent inhibitor of GPX4 with a KD value of 20.4 nM, exhibiting cytotoxic properties and anticancer activity.</p>
    Formula:C29H24N4O3S2
    Color and Shape:Solid
    Molecular weight:540.656
  • Adenylosuccinic acid tetraammonium


    <p>Adenylosuccinic acid, orally active, is a purine ribonucleotide involved in nucleotide metabolism, may aid in DMD studies.</p>
    Formula:C14H30N9O11P
    Color and Shape:Solid
    Molecular weight:531.42
  • Deacetylsclerotiorin

    CAS:
    <p>Deacetylsclerotiorin is a chloroazaphilones produced by the fungus Bartalinia robillardoides strain LF550.</p>
    Formula:C19H21ClO4
    Color and Shape:Solid
    Molecular weight:348.82
  • A3373

    CAS:
    <p>A3373 is a novel inhibitor targeting both Phospholipase D1 (PLD1) and Phospholipase D2 (PLD2), demonstrating half maximal inhibitory concentrations (IC50) of</p>
    Formula:C17H9F7N2O
    Purity:98%
    Color and Shape:Soild
    Molecular weight:390.26
  • Imperatoxin A

    CAS:
    <p>Imperatoxin A, a peptide toxin sourced from the African scorpion Pandinus imperator, functions as an activator of Ca2+-release channels/ryanodine receptors (</p>
    Formula:C148H254N58O45S6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:3758.35
  • Erythronic acid potassium


    <p>Potassium erythronate is an intrinsic carbohydrate metabolite utilized in researching metabolic diseases.</p>
    Formula:C4H7KO5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:173.99305
  • nSMase2-IN-1


    <p>nSMase2-IN-1 is an orally active inhibitor of Neutral sphingomyelinase 2 (nSMase2) with a potent IC50 value of 0.13 ± 0.06 μM.</p>
    Formula:C12H17N5O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:247.3
  • D,L-erythro-PDMP

    CAS:
    <p>D,L-erythro-PDMP inhibits growth in rabbit fibroblasts and blocks UDP-glucose: ceramide glucosyltransferase.</p>
    Formula:C23H38N2O3
    Color and Shape:Solid
    Molecular weight:390.568
  • CK1δ/CK1ε liagnd-1


    <p>CK1δ/CK1ε ligand-1 is a ligand of CK1δ/CK1ε and can serve as a target protein ligand for the synthesis of the CK1 PROTAC degrader AH078.</p>
    Formula:C21H20F2N6
    Color and Shape:Solid
    Molecular weight:394.42
  • PTPσ Inhibitor, ISP


    <p>PTPσ Inhibitor ISP is a compound that binds to recombinant human PTPs, thereby inhibiting PTPσ signaling.</p>
    Formula:C177H306N66O54S3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:4318.93
  • hCAXII-IN-7


    <p>hCAXII-IN-7 (compound 6e) functions as an inhibitor of human carbonic anhydrase XII (hCA XII) and possesses blood-brain barrier (BBB) permeability.</p>
    Formula:C26H25N5O6S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:567.64
  • α-Glucosidase-IN-31


    <p>α-Glucosidase-IN-31 (compound R1) is a potent oral α-Glucosidase inhibitor with an IC50 of 10.1 μM, demonstrating significant blood glucose reduction and</p>
    Formula:C18H18N4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:290.36
  • ω-Conotoxin CnVIIA

    CAS:
    <p>ω-Conotoxin CnVIIA, a 27-amino-acid neuropeptide toxin, serves as an N-type calcium current blocker [1].</p>
    Formula:C110H179N39O36S7
    Purity:98%
    Color and Shape:Solid
    Molecular weight:2848.29
  • (Rac)-BMS-816336


    <p>(Rac)-BMS-816336 is a racemic 11β-HSD1 inhibitor; IC50: 10 nM (human), 68 nM (mouse), metabolically stable.</p>
    Formula:C21H27NO3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:341.44
  • ZG-2033

    CAS:
    <p>ZG-2033 (Compound 26) is an orally active HIF-2α agonist that exhibits nanomolar activity (EC50 = 490 nM) in a luciferase reporter assay. It demonstrates an anti-anemic effect and shows synergistic effects with AKB-6548 in anemia, making it useful for the study of renal anemia.</p>
    Formula:C15H14N2O2S
    Color and Shape:Solid
    Molecular weight:286.35
  • PPARγ agonist 16

    CAS:
    <p>PPARγ agonist16 (Compound 4G) is a PPARγ agonist that competitively binds to the ligand-binding domain (LBD) of PPARγ with an IC50 of 1790 nM. It reduces ear swelling in mouse models and exhibits antihyperglycemic activity in mice with Streptozotocin-induced diabetes.</p>
    Formula:C19H14BrNO4S
    Color and Shape:Solid
    Molecular weight:432.29
  • Pyruvate carboxylase

    CAS:
    <p>Pyruvate carboxylase, a biotin-containing enzyme, catalyzes the carboxylation of pyruvate to oxaloacetate, a reaction dependent on HCO3− and MgATP.</p>
    Purity:98%
    Color and Shape:Solid
  • PDE11A4-IN-1


    <p>PDE11A4-IN-1 (compound 23b) is a potent, selective inhibitor of PDE11A4, demonstrating an IC50 of 12 nM and exhibiting high selectivity against PDE1, PDE2,</p>
    Color and Shape:Odour Solid
  • 5A2-SC8 TFA


    <p>5A2-SC8 TFA is an ionizable amino lipid used in lipid nanoparticles (LNPs), offering high delivery potential and low in vivo toxicity. It effectively delivers small RNAs, such as siRNA and miRNA, to tumor cells. Moreover, 5A2-SC8 TFA LNPs provide unique delivery paths for RNA within the liver, enhancing therapeutic outcomes in cancer models.</p>
    Color and Shape:Odour Solid
  • DHODH-IN-18

    CAS:
    <p>DHODH-IN-18 is a human DHODH inhibitor ( IC 50 = 0.2 nM).</p>
    Formula:C21H16ClF5N6O4
    Color and Shape:Solid
    Molecular weight:546.84
  • Ivabradine impurity 1

    CAS:
    <p>Ivabradine impurity 1, orally bioavailable HCN channel blocker.</p>
    Formula:C15H18BrNO3
    Color and Shape:Solid
    Molecular weight:340.21
  • Carpachromene


    <p>Carpachromene is a useful organic compound for research related to life sciences and the catalog number is T124630.</p>
    Formula:C20H16O5
    Color and Shape:Solid
    Molecular weight:336.343
  • Adenosine 3',5'-diphosphate sodium salt

    CAS:
    <p>Adenosine 3',5'-diphosphate sodium inhibits hydroxysteroid sulfotransferases and studies SULT kinetics/structure.</p>
    Formula:C10H15N5NaO10P2
    Purity:95%
    Color and Shape:Solid
    Molecular weight:450.19
  • C17 Sphingomyelin (d18:1/17:0)

    CAS:
    <p>C17 Sphingomyelin is a synthetic derivative of sphingomyelin that has been used as an internal standard for the quantification of sphingomyelin.</p>
    Formula:C40H81N2O6P
    Color and Shape:Solid
    Molecular weight:717.05
  • TPT-004


    <p>TPT-004, a TPH inhibitor, exhibits superior pharmacokinetic and pharmacodynamic properties, and demonstrates efficacy in preclinical models for attenuating</p>
    Color and Shape:Odour Solid
  • DSPE-PEG2000-K237


    <p>DSPE-PEG2000-K237 is a PEG compound consisting of DSPE and the KDR-targeting peptide (K237). K237 functionally disrupts the interaction between VEGF and KDR receptors, resulting in significant biological effects such as inhibition of angiogenesis and tumor growth. DSPE-PEG2000-K237 is applicable in drug delivery.</p>
    Color and Shape:Odour Solid
  • Cy3-PEG-DSPE (MW 3400)


    <p>Cy3-PEG-DSPE (MW 3400) is a PEG phospholipid that incorporates Cy3 dye, utilized for labeling proteins/nucleic acids and in fluorescence microscopy. It can self-assemble in aqueous solutions to form micelles/lipid bilayers, and is employed in the creation of liposomes or nanoparticles for delivering nutrients such as mRNA or DNA vaccines.</p>
    Color and Shape:Solid
    Molecular weight:3400 (Average)
  • QXG-6442


    <p>QXG-6442 is a molecular glue degrader targeting CK1α, demonstrating a degradation potency with a DC50 of 5.7 nM and a Dmax of 90%. In the MOLM-14 cell line, QXG-6442 induces antiproliferative effects.</p>
    Formula:C21H17N5O4
    Color and Shape:Solid
    Molecular weight:403.39
  • Roridin L2

    CAS:
    <p>Roridin L2 is a natural product for research related to life sciences. The catalog number is T41264 and the CAS number is 85124-22-7.</p>
    Formula:C29H38O9
    Color and Shape:Solid
    Molecular weight:530.614
  • N-Nonyldeoxynojirimycin

    CAS:
    <p>N-Nonyldeoxynojirimycin (NN-DNJ) is an inhibitor of acid α-glucosidase and α-1,6-glucosidase (IC50s = 0.42 and 8.4 μM, respectively).</p>
    Formula:C15H31NO4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:289.41
  • Voclosporin

    CAS:
    <p>Voclosporin (ISAtx-247) is a novel and orally available calcium-modulated phosphatase (CN; PP2B) inhibitor and immunosuppressant for the treatment of lupus</p>
    Formula:C63H111N11O12
    Purity:99.85%
    Color and Shape:Solid
    Molecular weight:1214.62
  • N4-Acetylcytidine triphosphate sodium

    CAS:
    <p>N4-Acetylcytidine triphosphate sodium is efficiently used as a substrate in T7 Polymerase-catalyzed in vitro transcription.</p>
    Formula:C11H18N3Na4O15P3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:617.15
  • Neoechinulin C

    CAS:
    <p>Neoechinulin C, a neuroprotective indolediketopiperazine, guards neurons against paraquat in Parkinson's.</p>
    Formula:C24H27N3O2
    Color and Shape:Solid
    Molecular weight:389.49
  • DCG04

    CAS:
    <p>DCG04: a mannose-6-phosphate receptor ligand, fluorescent cysteine cathepsin probe for endolysosomal targeting.</p>
    Formula:C43H66N8O11S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:903.11
  • Cholesteryl Homo-γ-Linolenate

    CAS:
    <p>Cholesteryl homo-γ-linolenate is a cholesterol ester.</p>
    Formula:C47H78O2
    Color and Shape:Solid
    Molecular weight:675.139
  • Archangelicin

    CAS:
    <p>Archangelicin is a useful organic compound for research related to life sciences. The catalog number is T125179 and the CAS number is 2607-56-9.</p>
    Formula:C24H26O7
    Color and Shape:Solid
    Molecular weight:426.465
  • Tajixanthone

    CAS:
    <p>Tajixanthone is the fungus metabolite from Aspergillus variecolor [1] .</p>
    Formula:C25H26O6
    Color and Shape:Solid
    Molecular weight:422.47
  • α-Glucosidase-IN-79


    <p>α-Glucosidase-IN-79 (Compound 4d9) is a non-competitive α-glucosidase inhibitor with an IC50 of 2.11 μM, demonstrating greater inhibitory potency than the existing α-glucosidase inhibitors Acarbose (IC50 of 327.0 μM) and HXH8r (IC50 of 15.32 μM). It exhibits no cytotoxicity on normal human liver cells (LO2) and shows good metabolic stability in rat plasma. α-Glucosidase-IN-79 holds promise for research in type 2 diabetes.</p>
    Formula:C21H22N2O5S
    Color and Shape:Solid
    Molecular weight:414.475