Metabolism
Metabolism inhibitors are compounds that interfere with metabolic pathways, altering the production and utilization of energy within cells. These inhibitors are used to study the regulation of metabolism, the role of metabolic pathways in diseases like cancer and diabetes, and to develop new therapeutic strategies. Metabolism inhibitors can target various enzymes and processes involved in glycolysis, fatty acid oxidation, and other metabolic functions. At CymitQuimica, we offer a wide range of high-quality metabolism inhibitors to support your research in biochemistry, metabolic disorders, and drug development.
Subcategories of "Metabolism"
- AhR(42 products)
- Aminopeptidase(76 products)
- CETP(20 products)
- Carbonic Anhydrase(197 products)
- Casein Kinase(137 products)
- DHFR(33 products)
- Decarboxylase(4 products)
- Dehydrogenase(303 products)
- FAAH(66 products)
- FXR(62 products)
- Factor Xa(87 products)
- Fatty Acid Synthase(37 products)
- Ferroptosis(226 products)
- GR(3 products)
- GSNOR(4 products)
- Glucokinase(57 products)
- HIF/HIF Prolyl-Hydroxylase(146 products)
- HMG-CoA Reductase(33 products)
- Hydroxylase(36 products)
- IDO(84 products)
- LDL(8 products)
- Lipase(107 products)
- Lipid(61 products)
- Lipoxygenase(134 products)
- MAO(87 products)
- MPO(2 products)
- NAMPT(40 products)
- P450(6 products)
- PAI-1(26 products)
- PDE(167 products)
- PED(1 products)
- PKM(17 products)
- PPAR(169 products)
- Phospholipase(84 products)
- ROR(47 products)
- Retinoid Receptor(26 products)
- SGK(10 products)
- Thioredoxin(12 products)
- Transferase(29 products)
- Transporter(45 products)
- UGT(4 products)
- Xanthine Oxidase (XO) Inhibitors(9 products)
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Found 9252 products of "Metabolism"
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GKA50 quarterhydrate
GKA50 quarterhydrate: glucokinase activator, EC50 of 33 nM, boosts insulin, cuts glucose in rats.Formula:C26H30N2O7Color and Shape:SolidMolecular weight:469.01SGK1-IN-3
CAS:SGK1-IN-3: Potent oral inhibitor of SGK1, may target osteoarthritis.Formula:C23H20Cl2N6O3SColor and Shape:SolidMolecular weight:531.414Xanthosine-5'-monophosphate
CAS:Xanthosine 5'-monophosphate is produced from inosine monophosphate (IMP) through the catalytic action of inosine monophosphate dehydrogenase (IMPDH).Formula:C10H13N4O9PColor and Shape:SolidMolecular weight:364.21HIF-2α-IN-7
CAS:HIF-2α-IN-7 is a hypoxia inducible factor 2α (HIF-2α) inhibitor.Formula:C18H9F6NO2Color and Shape:SolidMolecular weight:385.26NSC 828467
NSC 828467 is one of the top five CA-IX inhibitors with significant in vitro anticancer activity (IC50: 27.2 nM).Formula:C21H19N9O2SColor and Shape:SolidMolecular weight:461.5Nsp12-IN-2
CAS:Nsp12-IN-2 (Compound 8), a triphosphate metabolite of 4'-thiouridine, functions as an inhibitor of SARS-CoV-2 Nsp12. It effectively suppresses the RNA-dependent RNA polymerase (RdRp) activity of the SARS-CoV-2 Nsp12-Nsp7-Nsp8 complex, halting RNA synthesis and blocking the RNA capping and NMP capping of Nsp9. Nsp12-IN-2 shows potential for research into infections caused by SARS-CoV-2, other coronaviruses, and additional RNA viruses.Formula:C9H12N2Na3O14P3SColor and Shape:SolidMolecular weight:566.15HSD17B13-IN-19
CAS:HSD17B13-IN-19 (compound 16) acts as a potent inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), exhibiting IC50 values under 0.1 μM and under 1 μM when using estradiol and Leukotriene B3 as substrates, respectively. This compound is crucial in the treatment of nonalcoholic fatty liver diseases (NAFLDs), such as nonalcoholic steatohepatitis (NASH) [1].Formula:C23H23FN2O4SColor and Shape:SolidMolecular weight:442.5Z57346765
CAS:Z57346765 is a specific PGK1 inhibitor that inhibits PGK1-dependent cell proliferation by decreasing the metabolic enzyme activity of PGK1 during glycolysis.Formula:C17H18N4OPurity:99.85%Color and Shape:SolidMolecular weight:294.35PRL3-CNNM4 interaction-IN-1
CAS:PRL3-CNNM4 interaction-IN-1 (Compound C28d52) is an inhibitor of the PRL3-CNNM4 interaction that also suppresses CNNM inhibition mediated by PRL. This compound exhibits favorable pharmacokinetic and drug metabolism properties.Formula:C8H8O2SColor and Shape:SolidMolecular weight:168.21Osunprotafib hydrochloride
CAS:Osunprotafib (ABBV-CLS-484) hydrochloride is an orally active, selective inhibitor targeting the active sites of PTPN1 (IC50: 2.5 nM) and PTPN2 (IC50: 1.8 nM). It shows 6-8 times weaker activity towards PTPN9 and no detectable activity against SHP-1 or SHP-2. This compound enhances the sensitivity of human cancer cell lines to IFNγ. By boosting JAK-STAT signaling and reducing T cell dysfunction, Osunprotafib hydrochloride exhibits potent antitumor immunity.Formula:C17H25ClFN3O4SColor and Shape:SolidMolecular weight:421.929(S)-HEPE
CAS:9(S)-HEPE is a monohydroxy fatty acid derived from EPA. The biological activity of 9(S)-HEPE has not been documented.Formula:C20H30O3Color and Shape:SolidMolecular weight:318.45m-APTA
CAS:m-APTA (5'-S-(3-aminophenyl)-5'-thioadenosine) is a selective chemoprotective agent targeting methylthioadenosine phosphorylase (MTAP). It can be converted into adenine, which is a crucial step in shielding normal cells from the toxicity of nucleobase analogs (NBA). m-APTA holds potential for research in MTAP-deficient cancers.Formula:C16H18N6O3SColor and Shape:SolidMolecular weight:374.418Etamicastat
CAS:Etamicastat can be used in the research of cardiovascular diseases.Formula:C14H15F2N3OSPurity:98%Color and Shape:SolidMolecular weight:311.35Casein Kinase II Inhibitor IV Hydrochloride
CAS:Casein Kinase II Inhibitor IV HCl promotes keratinocyte differentiation, potential for skin disorder therapy.Formula:C24H24ClN5O3Purity:98%Color and Shape:SolidMolecular weight:465.93HSD17B13-IN-28
CAS:HSD17B13-IN-28 (compound 47) is a potent inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), with an IC50 of < 0.1 μM using estradiol as a substrate. HSD17B13-IN-28 plays an important role in nonalcoholic fatty liver diseases (NAFLDs), including NASH (nonalcoholic steatohepatitis) [1].Formula:C23H16Cl2FN3O3Color and Shape:SolidMolecular weight:472.317β-HSD1-IN-1
17β-HSD1-IN-1 (Compound 1) can be used in the non-small cell lung cancer (NSCLC) research.Formula:C21H21NO3Color and Shape:SolidMolecular weight:335.4GSK864
CAS:GSK864 is an inhibitor of isocitrate dehydrogenase 1 (IDH1) mutant. GSK864 inhibits IDH1 mutants R132C, R132H, and R132G (IC50: 8.8, 15.2, and 16.6 nM).Formula:C30H31FN6O4Purity:97.07%Color and Shape:SolidMolecular weight:558.6MAGL-IN-20
MAGL-IN-20 (compound ±34) is a reversible inhibitor of monoacylglycerol lipase (MAGL). It exhibits significant antiproliferative activity against a range of cancer cell lines, including H460, HT29, CT-26, Huh7, and HCCLM-3.Formula:C23H24N2OColor and Shape:SolidMolecular weight:344.45FXR agonist 9
CAS:FXR agonist9 (compound 26) is a selective, orally active partial agonist of FXR with an EC50 of 0.09 µM (maximum efficacy of 75.13%). It ameliorates the pathological features of fatty liver disease in mice induced by HFD and CCl4-related metabolic dysfunction.Formula:C28H30N2O5Color and Shape:SolidMolecular weight:474.55Pyripyropene A
CAS:Pyripyropene A is a potent and selective inhibitor of sterol O-acyltransferase 2 (SOAT2)/acyl-coenzyme A:cholesterol acyltransferase 2 (ACAT2)(IC50 of 0.07 μM).Formula:C31H37NO10Purity:98%Color and Shape:SolidMolecular weight:583.63
