Autophagy
Autophagy inhibitors target the cellular process of autophagy, which involves the degradation and recycling of cellular components through lysosomes. Autophagy is a critical mechanism for maintaining cellular homeostasis, but its dysregulation is implicated in various diseases, including cancer, neurodegeneration, and infections. Inhibitors of autophagy can block this process, making them valuable tools for studying the role of autophagy in disease and developing therapeutic strategies. At CymitQuimica, we offer autophagy inhibitors to support your research in cell biology, oncology, and neurodegenerative diseases.
Found 1504 products of "Autophagy"
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Silybin A
CAS:Silibinin, main component in milk thistle, offers liver protection and shows anti-cancer potential in various human cells.Formula:C25H22O10Purity:97.98% - 98.37%Color and Shape:SolidMolecular weight:482.44Tozasertib
CAS:Tozasertib (MK-0457) is a pan-Aurora kinase inhibitor (Kis: 0.6/18/4.6 nM for Aurora A/Aurora B/Aurora C).Formula:C23H28N8OSPurity:99.99%Color and Shape:SolidMolecular weight:464.59Regorafenib Hydrochloride
CAS:Regorafenib HCl (BAY73-4506) is an oral inhibitor targeting angiogenic, stromal, and cancer kinases with strong antitumor effects.Formula:C21H16Cl2F4N4O3Purity:99.56%Color and Shape:SolidMolecular weight:519.28Aloe emodin
CAS:Aloe emodin (Rhabarberone) is an interferon-inducing agent, for JEV （IC50=1 μg/mL） and EV71（IC50=0.33 μg/mL ）.Formula:C15H10O5Purity:97.00% - 99.61%Color and Shape:Orange SolidMolecular weight:270.24GSK343
CAS:GSK343, a specific and effective EZH2 inhibitor (IC50=4 nM), exhibits 60 fold specificity activity against EZH1, and >1000 fold specificity activity againstFormula:C31H39N7O2Purity:98% - 99.9%Color and Shape:SolidMolecular weight:541.69LYN-1604 dihydrochloride
CAS:LYN-1604 is a novel ULK1 activator.It inducing cell death involved in ATF3, RAD21, and caspase3, accompanied by autophagy and apoptosis.Formula:C33H45Cl4N3O2Purity:98.95% - 99.92%Color and Shape:SolidMolecular weight:657.54Ref: TM-T8808L
1mg35.00€5mg78.00€10mg117.00€25mg212.00€50mg316.00€100mg447.00€200mg628.00€1mL*10mM (DMSO)101.00€OSU-T315
CAS:OSU-T315 (OSU-T315 (1,5-regioisomer)) (1,5-regioisomer) is a ILK inhibitor.Formula:C30H30F3N5OPurity:98.69%Color and Shape:SolidMolecular weight:533.59Ref: TM-T5485
1mg88.00€5mg187.00€10mg298.00€25mg533.00€50mg755.00€100mg1,008.00€200mg1,359.00€1mL*10mM (DMSO)220.00€Ixazomib
CAS:Ixazomib (MLN2238) is a boron-based peptide proteasome inhibitor targeting β5 site (IC50: 3.4 nM), also affecting β1 and β2 sites.Formula:C14H19BCl2N2O4Purity:98% - 99.77%Color and Shape:SolidMolecular weight:361.03SBE13 Hydrochloride
CAS:SBE13 Hydrochloride (SBE 13 HCl) is an effective and specific PLK1 inhibitor (IC50: 0.2 nM); no inhibition om Aurora A kinase, Plk2/3.Formula:C24H28Cl2N2O4Purity:99.00% - ≥95%Color and Shape:SolidMolecular weight:479.4Oxyphenisatin acetate
CAS:Oxyphenisatin acetate inhibits the growth of the breast cancer cell lines MCF7, T47D, HS578T, and MDA-MB-468.Formula:C24H19NO5Purity:98% - 99.35%Color and Shape:SolidMolecular weight:401.41Tenovin-6 Hydrochloride
CAS:Tenovin-6 HCl: Inhibits SIRT1 (21µM), SIRT2 (10µM), HDAC8; potent p53 activator.Formula:C25H35ClN4O2SPurity:99.36%Color and Shape:SolidMolecular weight:491.09Ref: TM-T8480
1mg39.00€2mg51.00€5mg70.00€10mg88.00€25mg140.00€50mg226.00€100mg376.00€1mL*10mM (DMSO)73.00€YM-201636
CAS:YM201636 (IC50=33 nM), a specific PIKfyve inhibitor, is less effective to p110α and insensitive to Fabl, which is yeast orthologue.Formula:C25H21N7O3Purity:93.28% - 98.3%Color and Shape:SolidMolecular weight:467.48Ref: TM-T6110
1mg46.00€2mg60.00€5mg90.00€10mg170.00€25mg340.00€50mg532.00€100mg760.00€500mg1,558.00€1mL*10mM (DMSO)92.00€Doramapimod
CAS:Doramapimod (BIRB 796) is a highly potent inhibitor of p38 MAPK (Kd: 0.1 nM), but weakly inhibits c-RAF, Fyn, Lck, ERK-1, SYK, IKK2, and ZAP-70.Formula:C31H37N5O3Purity:97.14% - 98.80%Color and Shape:SolidMolecular weight:527.66Ref: TM-T6277
1g532.00€5mg34.00€10mg52.00€25mg74.00€50mg96.00€100mg120.00€200mg213.00€500mg359.00€1mL*10mM (DMSO)42.00€Veliparib dihydrochloride
CAS:Veliparib dihydrochloride (ABT-888 dihydrochloride) is a potent inhibitor of PARP1 and PARP2 with Ki of 5.2 nM and 2.9 nM in cell-free assays, respectively.Formula:C13H18Cl2N4OPurity:98% - 99.81%Color and Shape:SolidMolecular weight:317.21Ambroxol hydrochloride
CAS:Ambroxol hydrochloride (Mucosolvan) is a metabolite of BROMHEXINE that stimulates mucociliary action and clears the air passages in the respiratory tract.Formula:C13H18Br2N2O·HClPurity:99.70%Color and Shape:White To Yellowish Crystalline PowderMolecular weight:414.56CFTR corrector 2
CAS:CFTR corrector 2 (FDL169) is a novel and potent CFTR corrector for treating cystic fibrosis (CF) patients who carry the F508del mutation.Formula:C27H23FN4O4Purity:99.66%Color and Shape:SolidMolecular weight:486.49Ref: TM-T5312
2mg37.00€5mg55.00€10mg80.00€25mg147.00€50mg215.00€100mg318.00€200mg444.00€1mL*10mM (DMSO)59.00€ZLN005
CAS:ZLN005 is an effective and tissue-specific transcriptional activator of PGC-1α.Formula:C17H18N2Purity:98.59% - >99.99%Color and Shape:SolidMolecular weight:250.34TWS119
CAS:TWS119 is a GSK-3β inhibitor; capable of inducing neuronal differentiationFormula:C18H14N4O2Purity:98.14% - 99.63%Color and Shape:SolidMolecular weight:318.33Rutin hydrate
CAS:Rutin hydrate (Sophorin), a kind of glycoside, widely exists in many plants including citrus fruit.Formula:C27H32O17Purity:97.23%Color and Shape:SolidMolecular weight:628.53Liensinine diperchlorate
CAS:Liensinine Diperchlorate is an isoquinoline alkaloid extracted from the embryonic seeds of the sacred lotus.Formula:C37H44Cl2N2O14Purity:99.8% - ≥95%Color and Shape:SolidMolecular weight:811.67Bafilomycin A1
CAS:Bafilomycin A1 belongs to the macrolide class of antibiotics and is a V-ATPase (IC50=0.44 nM) that is specific and reversible.Formula:C35H58O9Purity:95.87% - 99.36%Color and Shape:SolidMolecular weight:622.83Belinostat
CAS:Belinostat (PXD101) is an inhibitor of hydroxamic acid-type histone deacetylase (HDAC, IC50 of 27 nM in HeLa cell extracts),and with antineoplastic activity.Formula:C15H14N2O4SPurity:99.75% - >99.99%Color and Shape:SolidMolecular weight:318.35Ref: TM-T8517
5mg46.00€10mg65.00€25mg92.00€50mg137.00€100mg195.00€200mg290.00€500mg492.00€1mL*10mM (DMSO)59.00€Quisinostat
CAS:Quisinostat (JNJ-26481585), a second-gen HDAC inhibitor, is most potent for HDAC1 (IC50 0.11 nM) and selectively affects HDACs 2, 4, 10, and 11.Formula:C21H26N6O2Purity:96.01% - ≥98%Color and Shape:SolidMolecular weight:394.47Isodeoxyelephantopin
CAS:Isodeoxyelephantopin can inhibit the growth of various tumor cells.Formula:C19H20O6Purity:99.88%Color and Shape:SolidMolecular weight:344.36Veliparib
CAS:Veliparib (ABT-888) (ABT-888) is an orally bioavailable inhibitor of PARP (Kis: 5.2/2.9 nM for PARP1/2). It enhances apoptosis and autophagy.Formula:C13H16N4OPurity:98.66% - 99%Color and Shape:SolidMolecular weight:244.29Ref: TM-T2591
5mg54.00€10mg77.00€25mg120.00€50mg195.00€100mg314.00€200mg512.00€500mg807.00€1mL*10mM (DMSO)60.00€Genistein
CAS:Genistein (NPI 031L) is a natural soy isoflavone, a multi-targeted tyrosine kinase inhibitor. Genistein has antitumor effects. Cost effective and quality assured.Formula:C15H10O5Purity:98.22% - 99.64%Color and Shape:Rectangular Or Six-Sided Rods From 60% Alcohol Dendritic Needles From Ether SolidMolecular weight:270.24(1E,6E)-Bis(demethoxy)curcumin
CAS:(1E,6E)-Bis(demethoxy)curcumin (Curcumin III) is a natural demethoxy derivative of curcumin,with anti-inflammatory and anti-cancer activities.Formula:C19H16O4Purity:97.45% - 98.39%Color and Shape:SolidMolecular weight:308.33Ref: TM-T6S1688
5mg42.00€10mg52.00€25mg81.00€50mg105.00€100mg152.00€500mg353.00€1mL*10mM (DMSO)49.00€Tomatidine
CAS:Tomatidine serves as an anti-inflammatory agent by inhibiting NF-κB and JNK signaling pathways.
Formula:C27H45NO2Purity:99.94% - 99.98%Color and Shape:SolidMolecular weight:415.65GNE-7915
CAS:GNE-7915 is a highly potent, selective and brain-penetrable leucine-rich repeat kinase 2 (LRRK2) inhibitor.Formula:C19H21F4N5O3Purity:98% - ≥95%Color and Shape:SolidMolecular weight:443.4Ref: TM-T1945
5mg44.00€10mg58.00€25mg108.00€50mg177.00€100mg299.00€200mg389.00€500mg645.00€1mL*10mM (DMSO)48.00€Dehydropachymic acid
CAS:Dehydropachymic acid shows antiinflammatory activity.Formula:C33H50O5Purity:99.61% - 99.78%Color and Shape:SolidMolecular weight:526.75Notoginsenoside Fc
CAS:1. Notoginsenoside Fc has perfect anti-platelet aggregatory effect.
Formula:C58H98O26Purity:99.22% - 99.94%Color and Shape:SolidMolecular weight:1211.38Cilofexor
CAS:Cilofexor inhibits binding of a synthetic peptide, Cilofexor is a farnesoid X receptor (FXR) agonist.Formula:C28H22Cl3N3O5Purity:99.86% - ≥95%Color and Shape:SolidMolecular weight:586.85Ref: TM-T7436
1mg52.00€2mg73.00€5mg117.00€10mg178.00€25mg356.00€50mg537.00€100mg708.00€200mg964.00€1mL*10mM (DMSO)149.00€Rosuvastatin
CAS:Rosuvastatin (ZD4522) is an inhibitor of HMG-CoA reductase (HMGCR). Rosuvastatin has hypolipidemic and antiatherosclerotic effects. Cost-effective and quality-assured.Formula:C22H28FN3O6SPurity:95.24% - 99.95%Color and Shape:SolidMolecular weight:481.54STF-31
CAS:STF-31 is an inhibitor of glucose transporter 1 (GLUT1) with IC50 of 1 μM.Formula:C23H25N3O3SPurity:99.55% - >99.99%Color and Shape:SolidMolecular weight:423.53Ref: TM-T5S2358
1mg49.00€2mg69.00€5mg105.00€10mg137.00€25mg197.00€50mg295.00€100mg447.00€1mL*10mM (DMSO)116.00€PI-1840
CAS:PI-1840 is a reversible and selective chymotrypsin-like (CT-L) inhibitor, with little proteasome proteolytic effects on trypsin-like (T-L) and PGPH-L.Formula:C22H26N4O3Purity:98.82%Color and Shape:SolidMolecular weight:394.47Liensinine
CAS:1. Liensinine, a kind of isoquinoline alkaloid, can antagonize the ventricular arrhythmias.Formula:C37H42N2O6Purity:98.92% - 99.93%Color and Shape:White-Like PowderMolecular weight:610.74Atorvastatin hemicalcium salt
CAS:Atorvastatin hemicalcium salt (Atorvastatin Calcium) is an orally HMG-CoA reductase inhibitor that lowers cholesterol. Cost-effective and quality-assured.Formula:C33H34FN2O5CaPurity:99.27% - >99.99%Color and Shape:White Crystalline PowderMolecular weight:577.67CZC-54252
CAS:CZC-54252 is a potent inhibitor of LRRK2.Formula:C22H25ClN6O4SPurity:99.39%Color and Shape:SolidMolecular weight:504.99Nilotinib monohydrochloride monohydrate
CAS:Nilotinib monohydrochloride monohydrate (Nilotinib (monohydrochloride monohydrate)) is significantly potent BCR-ABL against, is a second generation tyrosineFormula:C28H22F3N7O·HCl·H2OPurity:99.93%Color and Shape:SolidMolecular weight:583.99Autogramin-2
CAS:Autogramin-2 (tert-butyl 2-(4-isopropoxybenzamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate) potently inhibits autophagy induced by eitherFormula:C21H27N3O4SPurity:96.25%Color and Shape:SolidMolecular weight:417.52Vismodegib
CAS:Vismodegib (GDC-0449) is a hedgehog pathway inhibitor (IC50: 3 nM). It also inhibits P-gp (IC50: 3.0 μM), ABCG2 (IC50: 1.4 μM).Formula:C19H14Cl2N2O3SPurity:98% - 99.82%Color and Shape:SolidMolecular weight:421.3PFK-158
CAS:PFK-158 is an effective and specific inhibitor PFKFB3.Formula:C18H11F3N2OPurity:95.49% - 99.16%Color and Shape:SolidMolecular weight:328.29Ref: TM-T3105
1mg34.00€2mg46.00€5mg66.00€10mg90.00€25mg170.00€50mg259.00€100mg409.00€1mL*10mM (DMSO)73.00€Trametinib
CAS:Trametinib (GSK1120212), an ATP-noncompetitive MEK 1/2 inhibitor (IC50: 0.7/0.9 nM), weakly inhibits >180 kinases.Formula:C26H23FIN5O4Purity:98% - 99.96%Color and Shape:SolidMolecular weight:615.39Levosimendan
CAS:Levosimendan (OR1259) is a calcium sensitizer for acute heart failure, enhancing cardiac contractility without raising calcium levels.
Formula:C14H12N6OPurity:99.37% - 99.91%Color and Shape:Yellow Crystalline PowderMolecular weight:280.28Wogonin
CAS:Wogonin (Vogonin) is a cell-permeable and orally available flavonoid that displays anti-inflammatory and anticancer properties.Formula:C16H12O5Purity:98% - 99.8%Color and Shape:Yellow CrystalMolecular weight:284.26Ref: TM-T2933
5mg34.00€10mg42.00€25mg59.00€50mg92.00€100mg131.00€200mg178.00€500mg309.00€1mL*10mM (DMSO)52.00€SU9516
CAS:SU9516 is a potent CDK2 inhibitor, with an IC50 of 22 nM, and also has inhibitory effects on CDK1 and CDK4, with IC50s of 40 nM and 200 nM, respectively.Formula:C13H11N3O2Purity:99.34% - 99.96%Color and Shape:SolidMolecular weight:241.25Ref: TM-T6167
1mg34.00€2mg48.00€5mg70.00€10mg98.00€25mg197.00€50mg356.00€100mg530.00€500mg1,153.00€1mL*10mM (DMSO)71.00€10058-F4
CAS:10058-F4 inhibits c-Myc-Max, blocking c-Myc target gene activation, causing cell-cycle arrest & apoptosis.Formula:C12H11NOS2Purity:98% - 99.87%Color and Shape:SolidMolecular weight:249.35Soyasapogenol B
CAS:Soyasapogenol B has anti-cancer, hypocholesterolemic, anticomplementary, hepatoprotective effects, it inhibits proliferation of cultured Hep-G2.Formula:C30H50O3Purity:99.51% - 99.81%Color and Shape:SolidMolecular weight:458.72CZC-25146
CAS:CZC-25146, a stable LRRK2 inhibitor, IC50: 4.76 nM (wild-type), 6.87 nM (G2019S).Formula:C22H25FN6O4SPurity:97.68%Color and Shape:SolidMolecular weight:488.54N-Benzyllinolenamide
CAS:N-Benzyllinolenamide is a natural product. It is an inhibitor of fatty acid amide hydrolase (FAAH, IC50 of 41.8 μM).Formula:C25H37NOPurity:98.7% - 99.92%Color and Shape:SolidMolecular weight:367.57Ref: TM-TN1965
1mg81.00€5mg170.00€10mg260.00€25mg440.00€50mg628.00€100mg872.00€200mg1,153.00€1mL*10mM (DMSO)177.00€Amsacrine hydrochloride
CAS:Amsacrine hydrochloride (acridinyl anisidide hydrochloride) is topoisomerase II inhibitor , is used in the treatment of acute myelogenous leukemia.Formula:C21H20ClN3O3SPurity:99.05% - 99.92%Color and Shape:SolidMolecular weight:429.92Pantoprazole
CAS:Pantoprazole (BY1023) is a proton pump inhibitor used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal refluxFormula:C16H15F2N3O4SPurity:97.16% - 99.63%Color and Shape:Almost White SolidMolecular weight:383.37Sirtinol
CAS:Sirtinol is a selective SIRT1/2 inhibitor (IC50: 131/38 μM).Formula:C26H22N2O2Purity:97.12% - 99.96%Color and Shape:SolidMolecular weight:394.47Ref: TM-T6671
2mg40.00€5mg55.00€10mg88.00€25mg170.00€50mg324.00€100mg482.00€500mg1,063.00€1mL*10mM (DMSO)55.00€Embelin
CAS:Embelin (Embelic acid), isolated from the Japanese Ardisia herb, is an inhibitor of the X-linked inhibitor of apoptosis (IC50: 4.1 uM).Formula:C17H26O4Purity:97.07% - 99.88%Color and Shape:SolidMolecular weight:294.39GNE-9605
CAS:GNE-9605 is a highly effective, specifical, and brain-penetrant LRRK2 inhibitor (IC50: 19 nM).Formula:C17H20ClF4N7OPurity:98.55% - 98.75%Color and Shape:SolidMolecular weight:449.83PX-478
CAS:PX-478 is a HIF-1α inhibitor with selectivity, oral activity, and blood-brain barrier permeability.Formula:C13H20Cl4N2O3Purity:97% - 99.79%Color and Shape:SolidMolecular weight:394.12Ref: TM-T6961
1mg39.00€5mg84.00€10mg130.00€25mg193.00€50mg261.00€100mg411.00€200mg605.00€1mL*10mM (DMSO)84.00€Rotenone
CAS:Rotenone, a plant-derived insecticide, inhibits mitochondrial electron transport, found in Leguminosae.Formula:C23H22O6Purity:89.58% - 99.88%Color and Shape:Less To Brownish Crystals Or A White To Brownish-White Crystalline Powder Has Neither Odor Nor Taste (Ntp 1992)Molecular weight:394.42SMER28
CAS:SMER28 triggers autophagy in cells without mTOR, blocking amyloid beta buildup.Formula:C11H10BrN3Purity:99.94% - >99.99%Color and Shape:SolidMolecular weight:264.12Afatinib
CAS:Afatinib (BIBW 2992) is an irreversible and orally EGFR family inhibitor that inhibits EGFR and HER2. Afatinib has antitumor activity. Cost effective and quality assured.Formula:C24H25ClFN5O3Purity:98.56% - 99.9%Color and Shape:Off-White SolidMolecular weight:485.94Ref: TM-T21312
5mg34.00€10mg49.00€25mg81.00€50mg109.00€100mg137.00€200mg168.00€500mg284.00€1mL*10mM (DMSO)50.00€Mycro 3
CAS:Mycro 3 is potent and selective for c-Myc in whole cell assays.Formula:C24H17ClF2N6O4Purity:99.51% - 99.61%Color and Shape:SolidMolecular weight:526.88Ref: TM-T4367
1mg50.00€5mg94.00€10mg165.00€25mg318.00€50mg452.00€100mg627.00€200mg845.00€1mL*10mM (DMSO)110.00€Neferine
CAS:Neferine: anti-tumor, enhances DOX efficacy, prevents diabetic vasculopathy; mediates via CYP3A4, GSH depletion, blocks ROS/Akt/NF-κB.Formula:C38H44N2O6Purity:98.81% - 99.65%Color and Shape:SolidMolecular weight:624.77Isoalantolactone
CAS:Isoalantolactone (Isohelenin), isolated from Inula spp., can inhibit the growth of several types of Y cells.Formula:C15H20O2Purity:99.75% - 99.94%Color and Shape:SolidMolecular weight:232.32Zoledronic acid monohydrate
CAS:Zoledronic acid monohydrate (CGP 42446) is a synthetic imidazole bisphosphonate analog with anti-bone-resorption activity.Formula:C5H12N2O8P2Purity:99.91%Color and Shape:White To Off-White PowderMolecular weight:290.1Wogonoside
CAS:Wogonoside (Wogonin 7-O-glucuronide) acts as a positive allosteric modulator of the benzodiazepine site of the GABAA receptor.
Formula:C22H20O11Purity:98.24% - >99.99%Color and Shape:SolidMolecular weight:460.39Obatoclax Mesylate
CAS:Obatoclax Mesylate (GX15-070) is a Bcl-2 antagonist (Ki: 0.22 μM) and can induce apoptosis with up-regulation of Bim, induced cytochrome c release, andFormula:C20H19N3O·CH4O3SPurity:99.58% - 99.88%Color and Shape:SolidMolecular weight:413.49Chloroquine
CAS:Chloroquine: antimalarial, anti-inflammatory, autophagy/TLRs inhibitor, treats arthritis, effective against COVID-19 in vitro. EC50: 1.13 μM.Formula:C18H26ClN3Purity:99.5% - 99.98%Color and Shape:White To Slightly Yellow Crystalline Powder SolidMolecular weight:319.87A-484954
CAS:A-484954 (A 484954) is a highly specific eukaryotic elongation factor-2 (eEF2, IC50: 280 nM) inhibitor.Formula:C13H15N5O3Purity:97.47% - 99.86%Color and Shape:SolidMolecular weight:289.29Ref: TM-TQ0137
1mg40.00€2mg52.00€5mg84.00€10mg137.00€25mg289.00€50mg515.00€100mg733.00€1mL*10mM (DMSO)98.00€Salvigenin
CAS:Salvigenin is a potent hMAO-A inhibitor, has neuroprotective, antitumor and immunomodulatory effects.Formula:C18H16O6Purity:99.17% - 99.78%Color and Shape:SolidMolecular weight:328.32Leonurine
CAS:Leonurine (SCM-198) is an alkaloid that has been found in H. leonuri and with anti-oxidative and anti-inflammatory.Formula:C14H21N3O5Purity:98.55%Color and Shape:White Crystalline PowderMolecular weight:311.33Losmapimod
CAS:Losmapimod (GSK-AHAB) (GW856553X; SB856553; GSK-AHAB) is a specific, potent, and orally active p38 MAPK inhibitor (pKi: 8.1/7.6 for p38α/β).Formula:C22H26FN3O2Purity:98.35% - 99.89%Color and Shape:SolidMolecular weight:383.46Ref: TM-T2277
2mg34.00€5mg50.00€10mg73.00€25mg132.00€50mg213.00€100mg385.00€500mg873.00€1mL*10mM (DMSO)52.00€Indophagolin
CAS:Indophagolin: autophagy inhibitor, IC50 140 nM; blocks P2X4, P2X1, P2X3 receptors, IC50s 2.71, 2.40, 3.49 μM.Formula:C19H15BrClF3N2O3SPurity:99.76%Color and Shape:SolidMolecular weight:523.75Ref: TM-T8946
1mg42.00€5mg82.00€10mg116.00€25mg188.00€50mg260.00€100mg366.00€200mg497.00€1mL*10mM (DMSO)95.00€Pamapimod
CAS:Pamapimod (R1503) (R-1503, Ro4402257) is a novel, selective inhibitor of p38 mitogen-activated protein kinase.Formula:C19H20F2N4O4Purity:99.52% - 99.99%Color and Shape:SolidMolecular weight:406.38BIX-01294 trihydrochloride
CAS:BIX-01294 trihydrochloride is an inhibitor of G9a histone methyltransferase.In a cell-free assay, the IC50=2.7 μM for G9a histone methyltransferase.Formula:C28H38N6O2·3HClPurity:99.41% - 99.95%Color and Shape:SolidMolecular weight:600.02Ref: TM-T1959
2mg50.00€5mg67.00€10mg102.00€25mg182.00€50mg259.00€100mg447.00€200mg607.00€1mL*10mM (DMSO)105.00€CCT007093
CAS:CCT007093 is an effective PPM1D (WIP1) inhibitor (IC50: 8.4 μM).Formula:C15H12OS2Purity:98% - 99.88%Color and Shape:SolidMolecular weight:272.39Salubrinal
CAS:Salubrinal, a phosphatases (PP1) inhibitor(IC50=1.7 μM), exhibits function on the eukaryotic translation initiation factor 2 subunit (eIF2α).Formula:C21H17Cl3N4OSPurity:97.25% - >99.99%Color and Shape:SolidMolecular weight:479.81Ref: TM-T3045
2mg42.00€5mg62.00€10mg93.00€25mg163.00€50mg274.00€100mg465.00€500mg1,035.00€1mL*10mM (DMSO)67.00€Vacuolin-1
CAS:Vacuolin-1 is a cell-permeable inhibitor of Ca2+ dependent fusion of lysosomes to the cell membrane.Formula:C26H24IN7OPurity:97.20% - 98.45%Color and Shape:SolidMolecular weight:577.42Nobiletin
CAS:Nobiletin: a citrus-derived flavone with anti-inflammatory and anti-cancer properties; water-insoluble, very weak acid.Formula:C21H22O8Purity:98.65% - 99.76%Color and Shape:SolidMolecular weight:402.39Ref: TM-T2834
5mg54.00€10mg84.00€25mg117.00€50mg159.00€100mg251.00€200mg371.00€500mg620.00€1mL*10mM (DMSO)56.00€Lonafarnib
CAS:Lonafarnib (Sch66336) is an orally bioavailable FPTase inhibitor for H-ras, K-ras-4B, and N-ras (IC50: 1.9/5.2/2.8 nM).Formula:C27H31Br2ClN4O2Purity:98% - 99.94%Color and Shape:SolidMolecular weight:638.82Pyriproxyfen
CAS:Pyriproxyfen (S-31183) is an insecticide that acts as a biomimetic of juvenile hormone.Formula:C20H19NO3Purity:99.83%Color and Shape:Solid CompactMolecular weight:321.37Enzastaurin
CAS:Enzastaurin (LY317615) (LY317615) is an effective PKCβ selective inhibitor (IC50: 6 nM), 6- to 20-fold selectivity against PKCα/γ/ε.Formula:C32H29N5O2Purity:98% - >99.99%Color and Shape:SolidMolecular weight:515.6UNC0638
CAS:UNC0638 inhibits G9a and GLP lysine methyltransferases with IC50 <15 nM and 19 nM, respectively, showing high selectivity.Formula:C30H47N5O2Purity:98.88% - 99.53%Color and Shape:SolidMolecular weight:509.73CA-5f
CAS:CA-5f is a potent late-stage macroautophagy/autophagy inhibitor via inhibiting autophagosome-lysosome fusion.Formula:C24H24N2O3Purity:99.69%Color and Shape:SolidMolecular weight:388.46Chenodeoxycholic Acid sodium salt
CAS:Chenodeoxycholic Acid sodium salt (CDCA sodium salt) is a bile acid in humans that activates the nuclear receptor FXR, rescues axonal degeneration of induced pluripotent stem cell-derived neurons in patients with spastic paraplegia type 5 and cerebral xanthomatosis, and can be used to study pancreatic necrosis.Formula:C24H39NaO4Purity:99.68% - 99.72%Color and Shape:SolidMolecular weight:414.55Sitagliptin phosphate monohydrate
CAS:Sitagliptin phosphate monohydrate (MK-0431 phosphate monohydrate) is a potent inhibitor of DPP-IV with IC50 of 19 nM in Caco-2 cell extracts.Formula:C16H15F6N5O·H3PO4·H2OPurity:99.85% - 99.98%Color and Shape:White Or Almost White Crystalline PowderMolecular weight:523.33Latrepirdine dihydrochloride
CAS:Latrepirdine dihydrochloride (Dimebolin dihydrochloride) is an orally active, and neuroactive antagonist of multiple drug targets.Formula:C21H25N3·2HClPurity:98.45%Color and Shape:SolidMolecular weight:392.37Meloxicam
CAS:Meloxicam (Metacam) is a Nonsteroidal Anti-inflammatory Drug.Formula:C14H13N3O4S2Purity:97.09% - 99.60%Color and Shape:Light Yellow SolidMolecular weight:351.40Ketanserin tartrate
CAS:Ketanserin tartrate (KJK-945 tartrate) is a 5-HT2A receptor and α1-adrenergic receptor antagonist for the study of systemic sclerosis.Formula:C26H28FN3O9Purity:99.68%Color and Shape:SolidMolecular weight:545.51ML 145
CAS:ML 145 is a selective antagonist of GPR35/CXCR8 (IC50/EC50 of 20.1 nM)Formula:C24H22N2O5S2Purity:97.74%Color and Shape:SolidMolecular weight:482.57Ref: TM-T12074
1mg52.00€5mg100.00€10mg149.00€25mg250.00€50mg408.00€100mg572.00€1mL*10mM (DMSO)109.00€740 Y-P
CAS:740 Y-P (740YPDGFR) is a PI3K activator with cell permeability,binds GST fusion proteins containing the N-and C-terminal SH2 domains of p85. Low-Cost!Formula:C141H222N43O39PS3Purity:98.3% - 99.87%Color and Shape:SolidMolecular weight:3270.7Doxorubicin
CAS:Doxorubicin (Adriamycin) is a Topoisomerase II (Top2) inhibitor with antineoplastic activity.Formula:C27H29NO11Purity:99.31%Color and Shape:Red Crystalline Solid SolidMolecular weight:543.52Fluvastatin
CAS:Fluvastatin (XU-62320) is an HMG-CoA reductase inhibitor used to lower plasma cholesterol levels and prevent cardiovascular disease.Formula:C24H26FNO4Purity:98.94%Color and Shape:SolidMolecular weight:411.47H-89
CAS:H-89 is a PKA inhibitor, a candidate cardioprotectant, induces spatial learning impairment in rats, and can be used to study myocardial infarction.Formula:C20H20BrN3O2SPurity:98.06%Color and Shape:Off-White PowderMolecular weight:446.36Ref: TM-T11524
5mg38.00€10mg56.00€25mg108.00€50mg166.00€100mg240.00€500mg593.00€1mL*10mM (DMSO)42.00€SB 203580 hydrochloride
CAS:SB 203580 hydrochloride (Adezmapimod hydrochloride) is a p38 MAPK inhibitor that induces mitochondrial autophagy and cytosolic autophagy.Formula:C21H17ClFN3OSPurity:97.79%Color and Shape:SolidMolecular weight:413.9Ezetimibe ketone
CAS:Ezetimibe ketone (EZM-K) exhibits antioxidant activity and alleviates H2O2-induced NRK-52E cell apoptosis by upregulating Nrf2 and HO-1 levels.Formula:C24H19F2NO3Purity:99.32%Color and Shape:White Crystalline SolidMolecular weight:407.41mTOR inhibitor-8
CAS:mTOR inhibitor-8 is an mTOR inhibitor and autophagy inducer with antiviral and antitumor activity for the study of non-small cell lung cancer.Formula:C24H19ClN4OSPurity:98.11%Color and Shape:SolidMolecular weight:446.95Ref: TM-T36316
1mg50.00€5mg105.00€10mg170.00€25mg340.00€50mg557.00€100mg893.00€1mL*10mM (DMSO)110.00€Irinotecan-d10 Hydrochloride
CAS:Irinotecan-d10 Hydrochloride is a deuterated compound of Irinotecan Hydrochloride. Irinotecan Hydrochloride has a CAS number of 100286-90-6. Irinotecan Hydrochloride is the hydrochloride salt of a semisynthetic derivative of camptothecin. Irinotecan, a prodrug, is converted to a biologically active metabolite 7-ethyl-10-hydroxy-camptothecin (SN-38) by a carboxylesterase-converting enzyme. One thousand-fold more potent than its parent compound irinotecan, SN-38 inhibits topoisomerase I activity by stabilizing the cleavable complex between topoisomerase I and DNA, resulting in DNA breaks that inhibit DNA replication and trigger apoptotic cell death. Because ongoing DNA synthesis is necessary for irinotecan to exert its cytotoxic effects, it is classified as an S-phase-specific agent.Formula:C33H29D10ClN4O6Color and Shape:SolidMolecular weight:633.20Lovastatin-d3
CAS:Lovastatin-d3 is a deuterated compound of Lovastatin. Lovastatin has a CAS number of 75330-75-5. Lovastatin is an HMG-CoA Reductase Inhibitor, used for lowering cholesterol.Formula:C24H33D3O5Color and Shape:SolidMolecular weight:407.56Tigecycline-d9
CAS:Tigecycline-d9 is a deuterated compound of Tigecycline. Tigecycline has a CAS number of 220620-09-7. Tigecycline is a broad-spectrum glycylcycline antibiotic derived from tetracycline. Tigecycline binds to the 30S ribosomal subunit, thereby interfering with the binding of aminoacyl-tRNA to the mRNA-ribosome complex.Formula:C29H30D9N5O8Color and Shape:SolidMolecular weight:594.70Rosuvastatin-d6 Sodium Salt
CAS:Rosuvastatin-d6 Sodium Salt is a deuterated compound of Rosuvastatin Sodium Salt. Rosuvastatin Sodium Salt has a CAS number of 1007871-86-4.Formula:C22H21D6FN3NaO6SColor and Shape:SolidMolecular weight:509.56
