Apoptosis
Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.
Subcategories of "Apoptosis"
- ASK(9 products)
- BCL(1 products)
- Caspase(154 products)
- FOXO1(2 products)
- IAP(67 products)
- Mdm2(12 products)
- PD-1/PD-L1(127 products)
- PDK(9 products)
- PERK(23 products)
- Serine/threonin kinase(17 products)
- Survivin(14 products)
- TNF(90 products)
- c-RET(61 products)
- p53(63 products)
Show 6 more subcategories
Found 6170 products of "Apoptosis"
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Genistein
CAS:Genistein (NPI 031L) is a natural soy isoflavone, a multi-targeted tyrosine kinase inhibitor. Genistein has antitumor effects. Cost effective and quality assured.Formula:C15H10O5Purity:98.22% - 99.64%Color and Shape:Rectangular Or Six-Sided Rods From 60% Alcohol Dendritic Needles From Ether SolidMolecular weight:270.24(1E,6E)-Bis(demethoxy)curcumin
CAS:(1E,6E)-Bis(demethoxy)curcumin (Curcumin III) is a natural demethoxy derivative of curcumin,with anti-inflammatory and anti-cancer activities.Formula:C19H16O4Purity:97.45% - 98.39%Color and Shape:SolidMolecular weight:308.33Ref: TM-T6S1688
5mg42.00€10mg52.00€25mg81.00€50mg105.00€100mg152.00€500mg353.00€1mL*10mM (DMSO)49.00€AZ 628
CAS:AZ628 is a new pan-Raf inhibitor for BRAF, BRAFV600E, and c-Raf-1 with IC50 of 105 nM, 34 nM and 29 nM, also inhibits VEGFR2, DDR2, Lyn, Flt1, FMS, etc.Formula:C27H25N5O2Purity:99.50%Color and Shape:SolidMolecular weight:451.52Chelidonine
CAS:Chelidonine from Chelidonium majus triggers HeLa cell apoptosis, may reverse MDR, boost chemotherapeutics against leukemia, and inhibit cancer cell metastasis.Formula:C20H19NO5Purity:98% - 99.61%Color and Shape:SolidMolecular weight:353.37Tasisulam
CAS:Tasisulam (LY573636) is an apoptosis inducer and an antitumor agent via the intrinsic pathway.Formula:C11H6BrCl2NO3S2Purity:99% - >99.99%Color and Shape:SolidMolecular weight:415.11Ref: TM-T6191
5mg39.00€10mg58.00€25mg117.00€50mg193.00€100mg289.00€200mg434.00€500mg710.00€1mL*10mM (DMSO)56.00€Epibrassinolide
CAS:Epibrassinolide (BP55) (EBR) is a biologically active compound of the brassinosteroids, is a natural brassinosteroid (BR) derivative, is a plant regulator withFormula:C28H48O6Purity:97.57% - 98.11%Color and Shape:SolidMolecular weight:480.68Goserelin acetate
CAS:Goserelin acetate (Fertilan) is a synthetic long-acting agonist of gonadotropin-releasing hormone, used in treatments of cancer.
Formula:C61H88N18O16Purity:99.77% - >99.99%Color and Shape:White Crystalline PowderMolecular weight:1329.46PIK-75
CAS:PIK-75, a DNA-PK and PI3K inhibitor, suppresses DNA-PK(IC50=2 nM), p110α(IC50=5.8 nM) and p110γ(IC50=76 nM).
Formula:C16H14BrN5O4SPurity:98.52% - >99.99%Color and Shape:SolidMolecular weight:452.28Pifithrin-β hydrobromide
CAS:Pifithrin-β hydrobromide (Cyclic PFT-α) is an inhibitor of p53; reversibly blocks p53-dependent transcriptional activation and apoptosis.Formula:C16H17BrN2SPurity:99.24% - 99.74%Color and Shape:SolidMolecular weight:349.29Levomenol
CAS:Levomenol, or (-)-α-Bisabolol, is a sesquiterpene in aromatic plant oils with antioxidant, anti-inflammatory, and anti-apoptotic properties.Formula:C15H26OPurity:96.01%Color and Shape:Clear To Yellowish LiquidMolecular weight:222.37Isoalantolactone
CAS:Isoalantolactone (Isohelenin), isolated from Inula spp., can inhibit the growth of several types of Y cells.Formula:C15H20O2Purity:99.75% - 99.94%Color and Shape:SolidMolecular weight:232.32Zoledronic acid monohydrate
CAS:Zoledronic acid monohydrate (CGP 42446) is a synthetic imidazole bisphosphonate analog with anti-bone-resorption activity.Formula:C5H12N2O8P2Purity:99.91%Color and Shape:White To Off-White PowderMolecular weight:290.1Toddaculin
CAS:Toddaculine may be beneficial for the prevention and treatment of osteoporosis, it can not only inhibit the differentiation of osteoclasts via activation of theFormula:C16H18O4Purity:99.91%Color and Shape:SolidMolecular weight:274.31Hypericin
CAS:Hypericin (Cyclosan) is a natural anthraquinone compound. Hypericin exhibits antimicrobial, antiviral, antitumor, and antidepressant effects. Cost-effective and quality-assured.Formula:C30H16O8Purity:98.90% - ≥98%Color and Shape:Red-Coloured Anthraquinone-DerivativeMolecular weight:504.44Ref: TM-T6S0923
1mg54.00€5mg120.00€10mg172.00€25mg341.00€50mg504.00€100mg705.00€500mg1,431.00€1mL*10mM (DMSO)133.00€Afatinib
CAS:Afatinib (BIBW 2992) is an irreversible and orally EGFR family inhibitor that inhibits EGFR and HER2. Afatinib has antitumor activity. Cost effective and quality assured.Formula:C24H25ClFN5O3Purity:98.56% - 99.9%Color and Shape:Off-White SolidMolecular weight:485.94Ref: TM-T21312
5mg34.00€10mg49.00€25mg81.00€50mg109.00€100mg137.00€200mg168.00€500mg284.00€1mL*10mM (DMSO)50.00€Salvigenin
CAS:Salvigenin is a potent hMAO-A inhibitor, has neuroprotective, antitumor and immunomodulatory effects.Formula:C18H16O6Purity:99.17% - 99.78%Color and Shape:SolidMolecular weight:328.32Gardenin B
CAS:Gardenin B exhibits superior antiproliferative activity against lung, breast, colon, hepatic and leukaemia cell lines as well as in keratinocytes .Formula:C19H18O7Purity:98.80% - 99.74%Color and Shape:SolidMolecular weight:358.34Delanzomib
CAS:Delanzomib (CEP-18770) is an oral proteasome inhibitor with an IC50 of 3.8 nM, targeting chymotrypsin-like activity with minimal effect on other activities.Formula:C21H28BN3O5Purity:95.52% - 99.46%Color and Shape:SolidMolecular weight:413.28Ref: TM-T6027
1mg46.00€5mg96.00€10mg140.00€25mg274.00€50mg439.00€100mg660.00€200mg917.00€1mL*10mM (DMSO)95.00€Glycochenodeoxycholic Acid
CAS:Glycochenodeoxycholic Acid (Lithocholylglycine) is a glycine conjugate of lithocholic acid, a bile acid.Formula:C26H43NO5Purity:97% - 99.97%Color and Shape:SolidMolecular weight:449.62Ref: TM-T4588
5mg34.00€10mg49.00€25mg79.00€50mg104.00€100mg154.00€200mg220.00€500mg374.00€1mL*10mM (DMSO)54.00€Telekin
CAS:Telekin, a sesquiterpene lactone from Carpesium divaricatum, strongly inhibits cancer cell growth.Formula:C15H20O3Purity:99.86% - 99.97%Color and Shape:SolidMolecular weight:248.32AT7519
CAS:AT7519 is a CDK1/2/4/6/9 inhibitor (IC50: 10-210 nM). It is less effective to CDK3 and little active to CDK7.Formula:C16H17Cl2N5O2Purity:98.88% - 99.65%Color and Shape:SolidMolecular weight:382.24Malabaricone B
CAS:Malabaricone B is a Spice-derived phenolic, it induces mitochondrial damage in lung cancer cells via a p53-independent pathway.Formula:C21H26O4Purity:99.84% - 99.91%Color and Shape:SolidMolecular weight:342.43(E/Z)-TG003
CAS:(E/Z)-TG003 is a potent and ATP-competitive Cdc2-like kinase (Clk) inhibitor.Formula:C13H15NO2SPurity:98% - 99.04%Color and Shape:SolidMolecular weight:249.33Ref: TM-T1901
2mg42.00€5mg52.00€10mg92.00€25mg164.00€50mg271.00€100mg399.00€200mg567.00€1mL*10mM (DMSO)52.00€ENMD-2076
CAS:ENMD-2076, a multi-targeted kinase inhibitor, has specific activity against Aurora A, Flt3, KDR/VEGFR2, Flt4/VEGFR3, FGFR1, FGFR2, Src, PDGFRα.Formula:C21H25N7Purity:97.63% - ≥95%Color and Shape:SolidMolecular weight:375.47m-3M3FBS
CAS:m-3M3FBS is a phospholipase C (PLC) activator.Formula:C16H16F3NO2SPurity:99.66%Color and Shape:SolidMolecular weight:343.36Polygalacin D
CAS:Polygalacin D shows anti- proliferation, anti-inflammary, and hepatoprotective activities, it can inhibit the expression of lipopolysaccharide (LPS)-inducedFormula:C57H92O27Purity:98.95% - ≥98%Color and Shape:SolidMolecular weight:1209.4Salubrinal
CAS:Salubrinal, a phosphatases (PP1) inhibitor(IC50=1.7 μM), exhibits function on the eukaryotic translation initiation factor 2 subunit (eIF2α).Formula:C21H17Cl3N4OSPurity:97.25% - >99.99%Color and Shape:SolidMolecular weight:479.81Ref: TM-T3045
2mg42.00€5mg62.00€10mg93.00€25mg163.00€50mg274.00€100mg465.00€500mg1,035.00€1mL*10mM (DMSO)67.00€Choline
CAS:Choline is a ubiquitous water soluble nutrient, often associated with the B vitaminsFormula:C5H15NO2Purity:85% - ≥98%Color and Shape:LiquidMolecular weight:121.18MPTP hydrochloride
CAS:MPTP hydrochloride is a precursor of MPP+, a dopamine neurotoxin with blood-brain barrier permeability.Formula:C12H16ClNPurity:96.35% - >99.99%Color and Shape:SolidMolecular weight:209.72Ref: TM-T4081
5mg34.00€10mg52.00€25mg80.00€50mg131.00€100mg177.00€200mg281.00€500mg447.00€1mL*10mM (DMSO)50.00€CHR-6494 TFA
CAS:CHR-6494 TFA: potent haspin inhibitor (IC50=2 nM), blocks H3T3 phosphorylation, triggers apoptosis in cancer cells. Used for cancer research.Formula:C18H17F3N6O2Purity:99.50%Color and Shape:SolidMolecular weight:406.36Ref: TM-T9521
1mg60.00€5mg122.00€10mg190.00€25mg318.00€50mg452.00€100mg627.00€200mg845.00€1mL*10mM (DMSO)142.00€Obatoclax Mesylate
CAS:Obatoclax Mesylate (GX15-070) is a Bcl-2 antagonist (Ki: 0.22 μM) and can induce apoptosis with up-regulation of Bim, induced cytochrome c release, andFormula:C20H19N3O·CH4O3SPurity:99.58% - 99.88%Color and Shape:SolidMolecular weight:413.49CCT007093
CAS:CCT007093 is an effective PPM1D (WIP1) inhibitor (IC50: 8.4 μM).Formula:C15H12OS2Purity:98% - 99.88%Color and Shape:SolidMolecular weight:272.39Isocurcumenol
CAS:1. Isocurcumenol inhibits 5α-reductase which converts testosterone to dihydrotestosterone (DHT).Formula:C15H22O2Purity:99.29% - ≥95%Color and Shape:SolidMolecular weight:234.33Ref: TM-T5S0543
1mg66.00€5mg160.00€10mg250.00€25mg425.00€50mg610.00€100mg853.00€200mg1,144.00€1mL*10mM (DMSO)147.00€Neobavaisoflavone
CAS:Neobavaisoflavone: DNA polymerase inhibitor, potential for treating bone loss, anti-inflammatory, reduces ROS, RNS, cytokines in macrophages.Formula:C20H18O4Purity:99.31% - 99.92%Color and Shape:SolidMolecular weight:322.35Ref: TM-T6S0139
5mg46.00€10mg66.00€25mg99.00€50mg144.00€100mg205.00€500mg512.00€1mL*10mM (DMSO)49.00€RGX-202
CAS:RGX-202 (β-GPA) is an orally active inhibitor of the SLC6A8 transport protein. RGX-202 is a creatine analog that alters skeletal muscle energy expenditure.Formula:C4H9N3O2Purity:99.67% - 99.8%Color and Shape:SolidMolecular weight:131.13PD173955
CAS:PD173955 is src family-selective tyrosine kinase inhibitor with IC50 of ~22 nM for Src, Yes and Abl kinase; less potent for FGFRα and no activity on InsR andFormula:C21H16Cl2N4OSPurity:98.52% - 98.99%Color and Shape:SolidMolecular weight:443.35Ref: TM-T3063
2mg35.00€5mg50.00€10mg92.00€25mg166.00€50mg248.00€100mg371.00€200mg530.00€1mL*10mM (DMSO)94.00€Nobiletin
CAS:Nobiletin: a citrus-derived flavone with anti-inflammatory and anti-cancer properties; water-insoluble, very weak acid.Formula:C21H22O8Purity:98.65% - 99.76%Color and Shape:SolidMolecular weight:402.39Ref: TM-T2834
5mg54.00€10mg84.00€25mg117.00€50mg159.00€100mg251.00€200mg371.00€500mg620.00€1mL*10mM (DMSO)56.00€Bioymifi
CAS:Bioymifi (DR5 Activator), a novel TRAIL activator, binds to DR5's ECD, inducing DR5 aggregation and stimulating cell apoptosis. Cost-effective and quality-assured.Formula:C22H12BrN3O4SPurity:98% - 99.79%Color and Shape:SolidMolecular weight:494.32Ref: TM-T2065
1mg34.00€2mg47.00€5mg66.00€10mg102.00€25mg202.00€50mg364.00€100mg532.00€1mL*10mM (DMSO)79.00€Oncrasin-1
CAS:Oncrasin 1 is a potent inhibitor of anticancer that kills various human lung cancer cells with K-Ras mutations at low or submicromolar concentrationsFormula:C16H12ClNOPurity:99.75%Color and Shape:SolidMolecular weight:269.73TD52
CAS:TD52, an Erlotinib derivative, is an oral CIP2A cancer inhibitor that disrupts Elk1's attachment to the CIP2A promoter.Formula:C24H16N4Purity:99.5%Color and Shape:SolidMolecular weight:360.41DB1976 dihydrochloride
CAS:DB1976 dihydrochloride (DB1976 2HCl), a transcription factor PU.1 inhibitor, has potential anti-inflammatory activity for the study of metabolic dysfunction.Formula:C20H18Cl2N8SePurity:99.08%Color and Shape:SolidMolecular weight:520.28EPZ004777 hydrochloride
CAS:EPZ004777 hydrochloride (EPZ004777 HCl) is a potent, selective DOT1L inhibitor with IC50 of 0.4 nM.Formula:C28H42ClN7O4Color and Shape:SolidMolecular weight:576.13TREM2-IN-1
CAS:TREM2-IN-1 (OPA) is a platinum-based TREM2 inhibitor with anti-cancer and anti-tumor activity, inhibiting the immune-regulatory activity of TREM2 on macrophagesFormula:C46H68N2O20PtPurity:98.56%Color and Shape:SolidMolecular weight:1164.12Enzastaurin
CAS:Enzastaurin (LY317615) (LY317615) is an effective PKCβ selective inhibitor (IC50: 6 nM), 6- to 20-fold selectivity against PKCα/γ/ε.Formula:C32H29N5O2Purity:98% - >99.99%Color and Shape:SolidMolecular weight:515.6(S)-(+)-Rolipram
CAS:(S)-(+)-Rolipram ((+)-Rolipram) inhibits human monocyte cyclic AMP-specific PDE4 with IC50 of 0.75 μM, has anti-inflammatory and anti-depressant activity in theFormula:C16H21NO3Purity:99.14%Color and Shape:SolidMolecular weight:275.34KX2-361
CAS:KX2-361 is a orally bioavailable small molecule dual Src/tubulin inhibitor that provides long term survival in a murine model of glioblastomaFormula:C24H24FN3O2Purity:99.64% - 99.68%Color and Shape:SolidMolecular weight:405.46Ref: TM-T9411
1mg77.00€5mg161.00€10mg224.00€25mg366.00€50mg515.00€100mg692.00€200mg888.00€1mL*10mM (DMSO)172.00€SW106065
CAS:SW106065 is a novel pharmacologic inducer of apoptosis in MPNST (malignant peripheral nerve sheath tumors). SW106065 inhibits ATP consumption of sMPNST.Formula:C10H8N2OSPurity:99.97%Color and Shape:SolidMolecular weight:204.25Fipronil
CAS:Fipronil (Fluocyanobenpyrazole) is a broad-use insecticide that belongs to the phenylpyrazole chemical family.Formula:C12H4Cl2F6N4OSPurity:97.21%Color and Shape:Solid PowderMolecular weight:437.15Antineoplaston A10
CAS:Antineoplaston A10 (NSC-648539) is a Ras inhibitor potentially for the treatment of glioma, lymphoma, astrocytoma and breast cancer.Formula:C13H14N2O3Purity:99.42%Color and Shape:SolidMolecular weight:246.26Ref: TM-T7131
2mg44.00€5mg67.00€10mg103.00€25mg193.00€50mg295.00€100mg425.00€200mg595.00€1mL*10mM (DMSO)73.00€Apomine
CAS:Apomine (SR-9223i) 是一种 HMG-CoA-还原酶抑制剂，可在体外促进骨髓瘤细胞的凋亡，并与体内骨髓瘤的调节有关。 Apomine 加速 3-羟基-3-甲基戊二酰-CoA 还原酶的降解并刺激低密度脂蛋白受体活性。 Apomine 通过下调 3-羟基-3-甲基戊二酰-CoA 还原酶来增强洛伐他汀对骨髓瘤细胞的抗肿瘤作用。Formula:C28H52O7P2Purity:>99.99%Color and Shape:SolidMolecular weight:562.66Ralimetinib dimesylate
CAS:Ralimetinib dimesylate (LY2228820 dimesylate) is a orally available, p38 MAPK inhibitor with potential anti-inflammatory and antineoplastic activities.Formula:C24H29FN6·2CH4O3SPurity:98% - 99.38%Color and Shape:SolidMolecular weight:612.74Pomolic acid
CAS:Pomolic acid has anti-cancer, anti-inflammatory and apoptotic activities, it can induce apoptosis in SK-OV-3 cells, which is mediated by the mitochondrial-Formula:C30H48O4Purity:96.84% - 99.79%Color and Shape:SolidMolecular weight:472.7ML141
CAS:ML141 (CID-2950007) is an effective, specific and reversible non-competitive inhibitor of Rho family GTPase cdc42 (IC50: 200 nM).Formula:C22H21N3O3SPurity:99.36% - 99.56%Color and Shape:SolidMolecular weight:407.49Ref: TM-T2463
1mg37.00€2mg52.00€5mg69.00€10mg101.00€25mg200.00€50mg321.00€100mg515.00€1mL*10mM (DMSO)71.00€Crebanine
CAS:Crebanine mitigates arrhythmias, increases aconitine tolerance in rats, lacks effect on ouabain-induce arrhythmias, and shows anti-cancer properties.Formula:C20H21NO4Purity:99.17% - 99.77%Color and Shape:SolidMolecular weight:339.39DEL-22379
CAS:DEL-22379 is a water-soluble ERK dimerization inhibitor with IC50 of ～0.5 μM.Formula:C26H28N4O3Purity:99.3% - 99.53%Color and Shape:SolidMolecular weight:444.5318α-Glycyrrhetinic acid
CAS:18α-Glycyrrhetinic acid (Enoxolone) is a pentacyclic triterpenoid derivative of the beta-amyrin type obtained from the hydrolysis of glycyrrhizic acid.Formula:C30H46O4Purity:98.54% - 99.68%Color and Shape:SolidMolecular weight:470.68Candesartan Cilexetil
CAS:Candesartan Cilexetil, an angiotensin II blocker (IC50: 0.26 nM), turns to candesartan in the body, which dilates blood vessels by hindering AT1.Formula:C33H34N6O6Purity:98.22% - >99.99%Color and Shape:White Crystalline PowderMolecular weight:610.66Cilengitide
CAS:Cilengitide (EMD 121974) is a potent integrin inhibitor for the αvβ3/5 receptor (IC50: 4.1/79 nM, in cell-free assays); ~10-fold selectivity against gpIIbIIIa.Formula:C27H40N8O7Purity:98% - 99.8%Color and Shape:SolidMolecular weight:588.66Oprozomib
CAS:Oprozomib inhibits 20S proteasome β5/LMP7, is orally available, and may have cancer-fighting properties. IC50: β5 - 36 nM; LMP7 - 82 nM.Formula:C25H32N4O7SPurity:98% - 99.87%Color and Shape:SolidMolecular weight:532.61Rabeprazole sodium
CAS:Rabeprazole sodium treats stomach ulcers and Zollinger-Ellison syndrome, blocking ATPase in gastric cells.Formula:C18H20N3NaO3SPurity:98% - 99.912%Color and Shape:White Or Off White Crystalline PowderMolecular weight:381.42NVP-ADW742
CAS:NVP-ADW742 (ADW) is an IGF-1R inhibitor with IC50 of 0.17 μM, >16-fold more potent against IGF-1R than InsR; little activity to HER2, PDGFR, VEGFR-2, Bcr-AblFormula:C28H31N5OPurity:96.14% - 98.70%Color and Shape:SolidMolecular weight:453.58Glafenine Hydrochloride
CAS:Glafenine Hydrochloride is an anti-inflammatory agent.Formula:C19H17ClN2O4·HClPurity:98.89%Color and Shape:SolidMolecular weight:409.26Aminopurvalanol A
CAS:Aminopurvalanol A is a competitive, selective and cell-permeable inhibitor of cyclin-dependent kinase (CDK) that potently inhibits Cyclin A/cdk2, Cyclin B/cdk1Formula:C19H26ClN7OPurity:99.73%Color and Shape:SolidMolecular weight:403.91Ref: TM-T22260
2mg39.00€5mg60.00€10mg92.00€25mg173.00€50mg269.00€100mg389.00€200mg555.00€1mL*10mM (DMSO)62.00€Deltamethrin
CAS:Deltamethrin, a pyrethroid insecticide, causes reversible hind limb rigidity in rats and is used for crop protection and disease control.Formula:C22H19Br2NO3Purity:99.25% - 99.85%Color and Shape:White To Off-White Crystals Or PowderMolecular weight:505.20Mitochonic acid 5
CAS:MA-5, derived from a plant hormone, binds mitochondria and reduces heart/kidney damage, aiding mitochondrial disease survival.Formula:C18H13F2NO3Purity:98.85%Color and Shape:SolidMolecular weight:329.3Irigenin
CAS:Irigenin mediates its antimetastatic effect by specifically and selectively blocking the α9β1 and α4β1 integrin binding sites on the C-C loop of the ExtraFormula:C18H16O8Purity:99.50% - 99.85%Color and Shape:SolidMolecular weight:360.312BAct
CAS:2BAct is a novel eif2b activator, preventing neurological defects caused by a chronic integrated stress responseFormula:C19H16ClF3N4O3Purity:97.97% - 99.04%Color and Shape:SolidMolecular weight:440.8Betulinic acid
CAS:Betulinic acid, a lupane-type triterpene from white birch bark, has antiretroviral, antimalarial, anti-inflammatory, and anticancer properties.Formula:C30H48O3Purity:98.22% - 99.7%Color and Shape:White Crystalline PowderMolecular weight:456.70Nutlin-3
CAS:Nutlin-3 is an MDM2 antagonist that inhibits MDM2-p53 interaction and activates p53. Nutlin-3 has antitumor activity. Cost-effective and quality-assured.Formula:C30H30Cl2N4O4Purity:98.13% - 99.89%Color and Shape:SolidMolecular weight:581.49Desmorpholinyl Navitoclax-NH-Me
CAS:Desmorpholinyl Navitoclax-NH-Me (Desmorpholinyl ABT-263-NH-Me) is a Bcl-xL inhibitor, which can be employed alongside a CRBN ligand to synthesize XZ739, a
Formula:C44H51ClF3N5O5S3Purity:99.87%Color and Shape:SolidMolecular weight:918.55Pevonedistat
CAS:Pevonedistat (MLN4924) is a potent and selective NEDD8 activating enzyme (NAE) inhibitor (IC50=4.7 nM).Formula:C21H25N5O4SPurity:95% - 99.92%Color and Shape:SolidMolecular weight:443.52Ref: TM-T6332
1mg50.00€2mg66.00€5mg90.00€10mg137.00€25mg245.00€50mg401.00€100mg680.00€1mL*10mM (DMSO)88.00€Avadomide HCl
CAS:Avadomide (CC-122), an oral drug, targets CRBN, degrades Ikaros/Aiolos, and mimics interferon, showing antitumor effects in DLBCL.Formula:C14H15ClN4O3Color and Shape:SolidMolecular weight:322.75NAE-IN-M22
CAS:NAE-IN-M22: Selective, potent NEDD8 enzyme inhibitor; blocks cancer cell growth; induces apoptosis in A549 cells; effective in vivo.Formula:C20H24Cl2N2Purity:97.65%Color and Shape:SolidMolecular weight:363.32Ref: TM-T8816
1mg96.00€5mg205.00€10mg305.00€25mg518.00€50mg742.00€100mg1,018.00€500mg2,062.00€1mL*10mM (DMSO)227.00€Anagrelide hydrochloride
CAS:Anagrelide hydrochloride (BL4162A) serves as a treatment for essential thrombocytosis.
Formula:C10H7Cl2N3O·HClPurity:99.58%Color and Shape:Off-White PowderMolecular weight:292.55NSC622608
CAS:NSC622608, a VISTA ligand, modulates T-cell tumor attacks as an immune checkpoint.Formula:C9H12BrN3OS2Purity:98.48%Color and Shape:SolidMolecular weight:322.24Lercanidipine hydrochloride
CAS:Lercanidipine hydrochloride (Corifeo) is a calcium channel blocker of the dihydropyridine class.Formula:C36H41N3O6·HClPurity:99.86% - 99.91%Color and Shape:Pale-Yellow PowderMolecular weight:648.194-Oxofenretinide
CAS:4-Oxofenretinide (3-Keto fenretinide) , a recently identified fenretinide metabolite, induces marked G2-M cell cycle arrest and apoptosis.Formula:C26H31NO3Purity:96.89%Color and Shape:SolidMolecular weight:405.53Ref: TM-T4189
1mg42.00€2mg52.00€5mg74.00€10mg107.00€25mg185.00€50mg278.00€100mg500.00€1mL*10mM (DMSO)90.00€Lycorine
CAS:Lycorine (Narcissine) inhibits protein synthesis and may inhibit ascorbic acid biosynthesis, although studies on the latter are controversial and inconclusive.Formula:C16H17NO4Purity:98.60% - 99.95%Color and Shape:SolidMolecular weight:287.31AEE788
CAS:AEE788 (NVP-AEE 788) has been used in trials studying the treatment of Cancer, Glioblastoma Multiforme, and Brain and Central Nervous System Tumors.Formula:C27H32N6Purity:98% - >99.99%Color and Shape:SolidMolecular weight:440.58Ref: TM-T2116
2mg47.00€5mg70.00€10mg103.00€25mg188.00€50mg325.00€100mg490.00€500mg1,103.00€1mL*10mM (DMSO)77.00€Ibuprofen Lysine
CAS:Ibuprofen Lysine (Neoprofen) is a non-steroidal anti-inflammatory drug.Formula:C19H32N2O4Purity:99.26%Color and Shape:CoaMolecular weight:352.47BAY 61-3606 dihydrochloride
CAS:BAY 61-3606 dihydrochloride (BAY 61-3606) is a potent and selective inhibitor of Syk kinase (Ki = 7.5 nM).Formula:C20H18N6O3·2HClPurity:99.46%Color and Shape:SolidMolecular weight:463.32Ref: TM-T6776
1mg35.00€5mg79.00€10mg110.00€25mg177.00€50mg264.00€100mg385.00€200mg535.00€1mL*10mM (DMSO)93.00€1-(1-Naphthyl) piperazine hydrochloride
CAS:1-(1-Naphthyl) piperazine hydrochloride (1-naphthalen-1-ylpiperazine hydrochloride) is a serotonergic ligand which could bind nonselectively with multipleFormula:C14H17ClN2Purity:98.27%Color and Shape:SolidMolecular weight:248.75Bardoxolone Methyl
CAS:Bardoxolone Methyl (TP-155) is a synthetic triterpenoid that acts as an activator of the Nrf2 pathway and an inhibitor of the NF-κB pathway with potential anti-Formula:C32H43NO4Purity:97.81% - 99.09%Color and Shape:SolidMolecular weight:505.69MGH-CP1
CAS:MGH-CP1 inhibits TEAD2/4 auto-palmitoylation with IC50 of 710 and 672 nM, respectively.Formula:C20H24N4OSPurity:98.66%Color and Shape:SolidMolecular weight:368.5Ref: TM-T9032
2mg38.00€5mg57.00€10mg93.00€25mg177.00€50mg313.00€100mg507.00€200mg710.00€1mL*10mM (DMSO)67.00€Asiaticoside
CAS:Asiaticoside, in Centella asiatica, may treat wounds/burns.Formula:C48H78O19Purity:98% - 99.96%Color and Shape:PowderMolecular weight:959.12RA375
CAS:RA375 inhibits RPN13, enhances UPR, ROS, apoptosis, and is 10x more potent against cancer than RA190 due to nitro rings and chloroacetamide.Formula:C30H25ClN4O7Purity:99.56%Color and Shape:SolidMolecular weight:588.99MK-4101
CAS:MK-4101 inhibits Hedgehog pathway, causing apoptosis and reduced proliferation in cancer cells.Formula:C24H24F5N5OPurity:98.2% - 99.13%Color and Shape:SolidMolecular weight:493.47AZ960
CAS:AZ960 is an effective ATP competitive JAK2 inhibitor (IC50/Ki: <3 nM and0.45 nM).Formula:C18H16F2N6Purity:96.02% - 99.88%Color and Shape:SolidMolecular weight:354.36Ganetespib
CAS:Ganetespib (STA-9090) is a synthetic small-molecule inhibitor of heat shock protein 90 (Hsp90) with potential antineoplastic activity.Formula:C20H20N4O3Purity:98% - 99.95%Color and Shape:SolidMolecular weight:364.4Ref: TM-T2309
5mg63.00€10mg93.00€25mg126.00€50mg158.00€100mg236.00€200mg401.00€500mg665.00€1mL*10mM (DMSO)71.00€Gemcitabine hydrochloride
CAS:Gemcitabine hydrochloride (LY 188011 hydrochloride) is a synthetic cytosine nucleoside derivative and an inhibitor of DNA synthesis.Formula:C9H11F2N3O4·HClPurity:99.28% - 99.98%Color and Shape:White Crystalline Granular OdorlessMolecular weight:299.66SRT 2183
CAS:SRT 2183 is a selective activator of Sirtuin-1 (SIRT1, EC1.5 : 0.36 μM).Formula:C27H24N4O2SPurity:97.86%Color and Shape:SolidMolecular weight:468.57Ref: TM-T16932
1mg50.00€2mg72.00€5mg107.00€10mg165.00€25mg283.00€50mg430.00€100mg622.00€1mL*10mM (DMSO)111.00€2-Bromohexadecanoic acid
CAS:2-Bromohexadecanoic acid (2-BP) is a PPARδ agonist, and a palmitoylation inhibitor, inhibiting DHHC-mediated palmitoylation. Cost-effective and quality-assured.
Formula:C16H31BrO2Purity:97% - 98.3%Color and Shape:White Crystalline PowderMolecular weight:335.32Vildagliptin dihydrate
CAS:Vildagliptin dihydrate: potent, selective DPP-IV inhibitor with 3.5 nM IC50, high oral bioavailability, effective against hyperglycemia.Formula:C17H29N3O4Color and Shape:SolidMolecular weight:339.436TASIN-1 Hydrochloride
CAS:TASIN-1 Hydrochloride (TASIN-1 HCl) is a selective inhibitor of truncated APC that acts by selectively killing colorectal cancer cells that express truncatedFormula:C18H29ClN2O3SPurity:99.94%Color and Shape:SolidMolecular weight:388.95Ref: TM-T24855
1mg73.00€5mg136.00€10mg187.00€25mg318.00€50mg452.00€100mg627.00€200mg845.00€1mL*10mM (DMSO)142.00€Taurochenodeoxycholic Acid
CAS:Taurochenodeoxycholic Acid (12-Deoxycholyltaurine) is one of the main bioactive substances of animals' bile acid.Formula:C26H45NO6SPurity:99.53% - 99.86%Color and Shape:SolidMolecular weight:499.7Mycophenolic acid sodium
CAS:Mycophenolic acid sodium inhibits IMPDH with EC50 of 0.24 μM, has antiviral, immunosuppressive, antiangiogenic, and antitumor properties.Formula:C17H19NaO6Color and Shape:SolidMolecular weight:342.323Decursin
CAS:Decursin: potential antiepileptic, hepatoprotective, anti-cancer, anti-amnesic; affects NOX activation, PKCα/MAPK/NF-κB pathways, AChE.Formula:C19H20O5Purity:97.22% - 99.91%Color and Shape:SolidMolecular weight:328.36Ref: TM-T3S1416
1mg40.00€5mg84.00€10mg113.00€25mg245.00€50mg439.00€100mg627.00€500mg1,288.00€1mL*10mM (DMSO)93.00€Deguelin
CAS:Deguelin ((-)-Deguelin) is a PI3K/AKT Inhibitor, which is a natural product isolated from plants in the Mundulea sericea family.Formula:C23H22O6Purity:96.39% - 99.29%Color and Shape:SolidMolecular weight:394.42ASK1-IN-1
CAS:ASK1-IN-1 inhibits apoptosis kinase 1, crucial in cell stress responses, with 21 nM IC50.Formula:C19H19N9O2Purity:99.92%Color and Shape:SolidMolecular weight:405.41Ref: TM-T9697
1mg90.00€5mg215.00€10mg321.00€25mg582.00€50mg873.00€100mg1,216.00€1mL*10mM (DMSO)236.00€Erdafitinib
CAS:Erdafitinib (JNJ-42756493) is a quinoxaline derivative compound, acts on FGFR1/2/3/4.Formula:C25H30N6O2Purity:97.00% - 99.36%Color and Shape:SolidMolecular weight:446.54
