Ferroptosis
Ferroptosis is a form of regulated cell death characterized by the accumulation of lipid peroxides and iron-dependent oxidative stress. Unlike apoptosis, ferroptosis is not driven by caspases but rather by the failure of cellular antioxidant defenses, leading to cell death. Ferroptosis inhibitors and inducers are critical for studying this unique cell death pathway, which is implicated in various diseases, including cancer, neurodegeneration, and ischemia-reperfusion injury. At CymitQuimica, we offer a wide range of high-quality ferroptosis modulators to support your research in cell death mechanisms, oxidative stress, and disease pathology.
Found 215 products of "Ferroptosis"
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Simvastatin
CAS:Formula:C25H38O5Purity:>97.0%(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:418.57Erastin
CAS:Formula:C30H31ClN4O4Purity:>98.0%(HPLC)(qNMR)Color and Shape:White to Light yellow powder to crystalMolecular weight:547.056-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic Acid
CAS:Formula:C14H18O4Purity:>98.0%(GC)(T)Color and Shape:White to Orange to Green powder to crystalineMolecular weight:250.29Sulfasalazine
CAS:Formula:C18H14N4O5SPurity:>95.0%(T)(HPLC)Color and Shape:Light yellow to Amber to Dark green powder to crystalMolecular weight:398.39Ebselen
CAS:Formula:C13H9NOSePurity:>98.0%(GC)Color and Shape:Light orange to Yellow to Green powder to crystalMolecular weight:274.18Baicalein
CAS:Formula:C15H10O5Purity:>98.0%(T)Color and Shape:Light yellow to Amber to Dark green powder to crystalMolecular weight:270.24Coenzyme Q9
CAS:Formula:C54H82O4Purity:>98.0%(HPLC)Color and Shape:Light yellow to Yellow to Orange powder to crystalMolecular weight:795.25L-Glutamic Acid
CAS:Formula:C5H9NO4Purity:>99.0%(T)Color and Shape:White powder to crystalMolecular weight:147.13Ferrostatin-1
CAS:Formula:C15H22N2O2Purity:>98.0%(HPLC)Color and Shape:White to Amber to Dark purple powder to crystalMolecular weight:262.35Coenzyme Q10
CAS:Formula:C59H90O4Purity:>98.0%(HPLC)Color and Shape:Light yellow to Yellow to Orange powder to crystalMolecular weight:863.37Pioglitazone hydrochloride
CAS:<p>Pioglitazone hydrochloride (AD 4833) is the hydrochloride salt of an orally-active thiazolidinedione with antidiabetic properties and potential antineoplastic</p>Formula:C19H20N2O3S·HClPurity:99.64% - >99.99%Color and Shape:White Crystals Or Crystalline PowderMolecular weight:392.90Zileuton
CAS:<p>Zileuton (A 64077) inhibits 5-lipoxygenase, reduces leukotrienes, aids bronchodilation, lessens mucus/edema, and helps manage asthma symptoms.</p>Formula:C11H12N2O2SPurity:98.72% - 99.43%Color and Shape:Crystalline SolidMolecular weight:236.29iFSP1
CAS:<p>iFSP1, a potent, selective, and glutathione-independent ferroptosis suppressor protein 1 (FSP1) (AIFM2) inhibitor with an EC50 of 103 nM, sensitizes diverse</p>Formula:C20H13N5Purity:98.74% - 99.74%Color and Shape:SolidMolecular weight:323.35Simvastatin
CAS:<p>Simvastatin (MK 733) is an HMG-CoA reductase inhibitor (Ki=0.2 nM) with oral activity.</p>Formula:C25H38O5Purity:98.54% - 99.13%Color and Shape:SolidMolecular weight:418.57Linagliptin
CAS:<p>Linagliptin (BI 1356) is a potent, orally bioavailable dihydropurinedione-based inhibitor of dipeptidyl peptidase 4 (DPP-4), with hypoglycemic activity.</p>Formula:C25H28N8O2Purity:99.15% - >99.99%Color and Shape:SolidMolecular weight:472.54Lovastatin
CAS:<p>Lovastatin (MK-803) is an HMG-CoA reductase inhibitor. Lovastatin lowers cholesterol and is used as a lipid-lowering agent. Cost-effective and quality-assured.</p>Formula:C24H36O5Purity:99.66% - 99.92%Color and Shape:The Substance Is A White-Yellowish To Yellow Powder Solid PowderMolecular weight:404.54Eugenol
CAS:<p>Eugenol (Allylguaiacol) is a Standardized Chemical Allergen.</p>Formula:C10H12O2Purity:98.03%Color and Shape:Colorless Or Pale Yellow Liquid Pungent Taste (Ntp 1992)Molecular weight:164.2Pravastatin sodium
CAS:<p>Pravastatin sodium (CS-514 (sodium)), an HMG-CoA reductase inhibitor, inhibits sterol synthesis with IC50 of 5.6 μM.</p>Formula:C23H35NaO7Purity:97.14%Color and Shape:White Crystalline PowderMolecular weight:446.52Cisplatin
CAS:<p>Cisplatin (CDDP) is a DNA cross-linking agent.</p>Formula:Cl2H6N2PtPurity:97.13% - 99.63%Color and Shape:Orange-Yellow To Deep Yellow Solid Or PowderMolecular weight:300.04Ciclopirox olamine
CAS:<p>Ciclopirox olamine is a broad-spectrum antifungal agent with additional antibacterial and anti-inflammatory activities.</p>Formula:C14H24N2O3Purity:99.16% - >99.99%Color and Shape:White To Yellow Solid Solid Particulate/PowderMolecular weight:268.35NVS-ZP7-4
CAS:<p>NVS-ZP7-4 is a inhibitor of Zinc transporter SLC39A7 (ZIP7).</p>Formula:C28H28FN5OSPurity:99.86%Color and Shape:SolidMolecular weight:501.62Matrine
CAS:<p>Matrine (Vegard), an alkaloid isolated from the Sophora genus, acts as a kappa opioid receptor agonist.</p>Formula:C15H24N2OPurity:97.16% - >99.99%Color and Shape:SolidMolecular weight:248.36Lapatinib ditosylate monohydrate
CAS:<p>Lapatinib ditosylate monohydrate: a drug for advanced breast cancer; may cause liver issues.</p>Formula:C29H26ClFN4O4S·2(C7H8O3S)·H2OPurity:98% - 99.41%Color and Shape:Colourless To Light-Yellow CrystalMolecular weight:943.47Gallic acid
CAS:<p>Gallic acid (Benzoic acid) is found in almost all plants. Plants known for their high gallic acid content include gallnuts,grapes,tea,hops and oak bark.</p>Formula:C7H6O5Purity:99.38% - 99.57%Color and Shape:White Solid Solid Particulate/PowderMolecular weight:170.12Vildagliptin
CAS:<p>Vildagliptin (LAF237), an oral DPP-4 inhibitor with hypoglycemic effects, is metabolized and excreted in urine.</p>Formula:C17H25N3O2Purity:97.81% - >99.99%Color and Shape:White Crystalline PowderMolecular weight:303.40Ref: IN-DA00396N
1g24.00€5g40.00€10g57.00€1kgTo inquire25g99.00€2kgTo inquire50g141.00€5kgTo inquire100g196.00€DL-Glutamine
CAS:<p>DL-Glutamine, a non-essential amino acid, is abundant in the body, aids metabolism, carries nitrogen, and fuels cells.</p>Formula:C5H10N2O3Purity:99.89%Color and Shape:White Crystalline Powder White Crystalline PowderMolecular weight:146.14Ethylenediaminetetraacetic acid trisodium salt
CAS:<p>Ethylenediaminetetraacetic acid trisodium salt (EDTA Trisodium) used to bind metal ions in the chelation therapy.</p>Formula:C10H13N2Na3O8Purity:99.92% - 99.96%Color and Shape:White CrystalsMolecular weight:358.19Roxadustat
CAS:<p>Roxadustat (FG-4592) is an orally bioavailable, hypoxia-inducible factor prolyl hydroxylase inhibitor (HIF-PHI), with potential anti-anemic activity.</p>Formula:C19H16N2O5Purity:99% - 99.88%Color and Shape:SolidMolecular weight:352.34Lapatinib Ditosylate
CAS:<p>Lapatinib Ditosylate (Tykerb ditosylate) is an effective EGFR and ErbB2 inhibitor (IC50: 10.8/9.2 nM for EGFR/ErbB2).</p>Formula:C29H26ClFN4O4S·2C7H8O3SPurity:99.41%Color and Shape:Yellow SolidMolecular weight:925.46Curcumin
CAS:<p>Curcumin (Natural Yellow 3) is a phenolic natural product, an inhibitor of histone acetyltransferase p300/CREB (IC50=25 μM) with specificity.</p>Formula:C21H20O6Purity:95% - 98.98%Color and Shape:Orange-Yellow Crystal Powder; Gives Brownish-Red Color With Alkali; Light-Yellow Color With Acids Physical Description Orange-Yellow Needles (Ntp 1992)Molecular weight:368.3799FSEN1
CAS:<p>FSEN1 is a novel and highly effective non-competitive FSP1 inhibitor with an IC50 value of 313 nM.</p>Formula:C22H22BrN5OSPurity:98.56% - 99.54%Color and Shape:SolidMolecular weight:484.412-(10-hydroxydecyl)-6-methoxy-3-methyl-5-(trideuteriomethoxy)cyclohexa-2,5-diene-1,4-dione
CAS:Formula:C19H30O5Purity:98%Color and Shape:SolidMolecular weight:338.4385Sulfasalazine
CAS:<p>Sulfasalazine (Azulfidine) is a synthetic salicylic acid derivative. Sulfasalazine induces ferroptosis and inhibits NF-κB. Cost effective and quality assured.</p>Formula:C18H14N4O5SPurity:98.00% - 99.28%Color and Shape:Minute Brownish-Yellow CrystalsMolecular weight:398.39Ciclopirox
CAS:<p>Ciclopirox is an antifungal that chelates Fe3+ and Al3+, inhibiting enzymes and has antibacterial and anti-inflammatory effects.</p>Formula:C12H17NO2Purity:97.72% - 99.78%Color and Shape:SolidMolecular weight:207.27L-Glutathione reduced
CAS:<p>L-Glutathione reduced (Glutathione) is a naturally occurring tripeptide found in cells as an endogenous antioxidant that scavenges oxygen free radicals.</p>Formula:C10H17N3O6SPurity:97.37% - 99.99%Color and Shape:SolidMolecular weight:307.32Sorafenib tosylate
CAS:<p>Sorafenib tosylate (Bay 43-9006) is a potent multikinase inhibitor (IC50s: 6/20/22 nM for Raf-1/VEGFR-3/B-Raf).</p>Formula:C21H16ClF3N4O3·C7H8O3SPurity:99.24% - 99.94%Color and Shape:White To Off-White Crystalline PowderMolecular weight:637.03Butylhydroxyanisole
CAS:<p>BHA is an antioxidant with two isomers: 2-tert-butyl-4-hydroxyanisole and 3-tert-butyl-4-hydroxyanisole.</p>Formula:C11H16O2Purity:99.54% - 99.63%Color and Shape:White Solid WaxyMolecular weight:180.256-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid
CAS:Formula:C14H18O4Purity:98%Color and Shape:SolidMolecular weight:250.2903Ref: IN-DA003N8E
1g30.00€5g66.00€10g114.00€1kgTo inquire25g159.00€50g284.00€100g526.00€500gTo inquire100mg21.00€250mg25.00€(1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl 2,2-dimethylbutanoate
CAS:Formula:C25H38O5Purity:98%Color and Shape:SolidMolecular weight:418.5662Dopamine hydrochloride
CAS:<p>Dopamine hydrochloride (ASL279) is a natural catecholamine neurotransmitter, dopamine receptors (D1-5 receptors) (EC50=2.7 nM). High-Quality, Low-Cost!</p>Formula:C8H12ClNO2Purity:99.47% - 99.72%Color and Shape:SolidMolecular weight:189.64L-Glutamine
CAS:<p>L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid present in the human body and involved in many metabolic processes. High-Quality, Low-Cost!</p>Formula:C5H10N2O3Purity:99.66% - 99.98%Color and Shape:Solid CrystallineMolecular weight:146.14Baicalein
CAS:<p>Baicalein (5,6,7-Trihydroxyflavone) is a xanthine oxidase inhibitor.</p>Formula:C15H10O5Purity:97.06% - 98.48%Color and Shape:Yellow Crystalline SolidMolecular weight:270.24Sorafenib
CAS:<p>Sorafenib (Bay 43-9006) is a multikinase inhibitor that inhibits Raf-1, B-Raf, VEGFR2, VEGFR3, VEGFR4, PDGFRβ, FLT3, c-Kit, and others (IC50=6/22/90/15/20/20/57</p>Formula:C21H16ClF3N4O3Purity:98% - 99.89%Color and Shape:SolidMolecular weight:464.82Deferasirox
CAS:<p>Deferasirox (CGP-72670) is an oral iron chelating agent used to treat chronic iron overload.</p>Formula:C21H15N3O4Purity:98.79% - 99.4%Color and Shape:SolidMolecular weight:373.36Rosiglitazone maleate
CAS:<p>Rosiglitazone maleate (BRL 49653) is an oral antidiabetic and potential anticancer agent.</p>Formula:C22H23N3O7SPurity:99.33% - 99.51%Color and Shape:Off-White SolidMolecular weight:473.50Imidazole ketone erastin
CAS:<p>View and buy Imidazole ketone erastin from TargetMol.Imidazole ketone erastin (IKE) is an inducer of ferroptosis. It has inhibition of the system Xc- cystine/glutamate transporter.Cited in 22 publications.</p>Formula:C35H35ClN6O5Purity:98.48% - 99.87%Color and Shape:SolidMolecular weight:655.14Acetylcysteine
CAS:<p>Acetylcysteine (NAC) is an N-acetyl derivative of cysteine, a ROS inhibitor and mucolytic agent.</p>Formula:C5H9NO3SPurity:98.01% - >99.99%Color and Shape:Crystals From Water SolidMolecular weight:163.19α-Vitamin E
CAS:<p>α-Vitamin E (Dexrabeprazole Sodium) is a naturally-occurring form of vitamin E, a fat-soluble vitamin with potent antioxidant properties.</p>Formula:C29H50O2Purity:98% - 99.89%Color and Shape:Light Yellow LiquidMolecular weight:430.71Deferiprone
CAS:<p>Deferiprone (Deferidone) is an Iron Chelator. The mechanism of action of deferiprone is as an Iron Chelating Activity.</p>Formula:C7H9NO2Purity:99.58% - ≥95%Color and Shape:White NeedlesMolecular weight:139.15Fluvastatin sodium
CAS:<p>Fluvastatin sodium (Fluvastatin sodium salt), a competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase (HMGCR), is a commonly used cholesterol</p>Formula:C24H25FNNaO4Purity:98.54% - 99.56%Color and Shape:Light Yellow Solid PowderMolecular weight:433.45Lapatinib
CAS:<p>Lapatinib (GW572016) is an inhibitor of ErbB2 and EGFR (IC50=9.2/10.8 nM) with oral activity.</p>Formula:C29H26ClFN4O4SPurity:99.00% - 99.81%Color and Shape:PowderMolecular weight:581.06Butylated hydroxytoluene
CAS:<p>Butylated hydroxytoluene (BHT FCC/NF) is an organic chemical composed of 4-methylphenol modified with tert-butyl groups at positions 2 and 6.</p>Formula:C15H24OPurity:99.72%Color and Shape:Colourless Solid PowderMolecular weight:220.35Artesunate
CAS:<p>Artesunate (WR-256283) is part of the artemisinin group of drugs that treat malaria.</p>Formula:C19H28O8Purity:97.67% - 99.9%Color and Shape:White Crystalline PowderMolecular weight:384.42Pioglitazone
CAS:<p>Pioglitazone (U 72107) is a selective and oral PPARγ agonist with EC50 of 0.93 and 0.99 μM on human and mouse PPARγ, respectively . High-Quality, Low-Cost!</p>Formula:C19H20N2O3SPurity:95% - 99.57%Color and Shape:White PowderMolecular weight:356.44Artemisinin
CAS:<p>Artemisinin (Qinghaosu) is a natural sesquiterpene lactone. Artemisinin has anti-malarial, neuroprotective and anti-tumor effects. Cost-effective and quality-assured.</p>Formula:C15H22O5Purity:99.77% - 99.87%Color and Shape:Crystalline SolidMolecular weight:282.33GDCNF-11
CAS:<p>GDCNF-11, an HSP90-based HIM-PROTACGPX4 degrader, facilitates the ubiquitination and degradation of GPX4 through the HSP90 chaperone complex. This reduction in endogenous GPX4 induces ferroptosis in HT-1080 cells, with a DC50 value of 0.08 μM.</p>Formula:C48H53Cl2N13O5SColor and Shape:SolidMolecular weight:994.99Ferroptosis inducer-6
CAS:<p>Ferroptosisinducer 6 (6d) is an inducer of ferroptosis (ferroptosis) that exhibits potent potential for Type I/II photodynamic therapy by inducing ROS production, oxidative stress, and mitochondrial damage. Additionally, it demonstrates antitumor activity.</p>Formula:C69H78F12N12P2RuColor and Shape:SolidMolecular weight:1466.44Fluorescein-diisobutyrate-6-amide
CAS:<p>Fluorescein-diisobutyrate-6-amide, a powerful inducer of ferroptosis, shows promise for cancer research applications [1].</p>Formula:C62H61ClN6O16Color and Shape:SolidMolecular weight:1181.63NC-R17
<p>NC-R17, an RSL3-based noncovalent GPX4 degrader implicated in ferroptosis, demonstrates anti-tumor activity and is utilized in the design of noncovalent GPX4-</p>Formula:C53H67N7O7Purity:98%Color and Shape:SolidMolecular weight:914.14Ferroptosis-IN-12
<p>Ferroptosis-IN-12 (Cpd-A1) is an inhibitor of ferroptosis. It effectively suppresses ferroptosis in mouse renal tubular epithelial cells (mTECs) treated with Erastin and improves renal function in dose-dependent manners in mouse models of acute kidney injury (AKI) induced by ischemia/reperfusion (I/R) or cecal ligation and puncture (CLP). This compound also reduces renal tubular damage and eliminates inflammation. Exhibiting good plasma stability and high distribution in renal tissues during pharmacokinetic studies in mice, Ferroptosis-IN-12 shows promising potential for research in the field of AKI.</p>Color and Shape:Odour SolidFerroptosis inducer-4
<p>Ferroptosisinducer-4 (Compound 5) is a phospholipid-based ferroptosis inducer featuring a terminal double bond at the sn-2 position. It exhibits significant cytotoxicity towards HT-1080 cells with an IC50 value of 18 μM. The toxicity mechanism involves the generation of lipid peroxides and oxidative damage to the cell membrane induced by the terminal double bond. Ferroptosisinducer-4 can be utilized in studies pertaining to the regulation of ferroptosis.</p>Formula:C33H64NO7PColor and Shape:SolidMolecular weight:617.84GPX4-IN-7
<p>GPX4-IN-7 (Compound 31), an indirubin derivative, serves as a ferroptosis inducer in colon cancer treatment.</p>Formula:C25H23ClN4O4Purity:98%Color and Shape:SolidMolecular weight:478.93Ru-Poma
<p>Ru-Poma is an Ru(II)-based photosensitizer designed to enhance the efficacy of photodynamic therapy (PDT) against tumors resistant to Cisplatin. It targets Pomalidomide to partially degrade CRBN, inducing ferroptosis by increasing lipid peroxides and downregulating GPX4 and GAPDH expression. In A549 cells, Ru-Poma exhibits cytotoxicity with IC50 values of 18.46 μM in the dark and 0.37 μM under illumination.</p>Formula:C89H75Cl2N11O11Ru·7H2OPROTAC GPX4 degrader-2
<p>PROTACGPX4 degrader-2 (compound 18a) is a proteolysis-targeting chimera (PROTAC) that targets the degradation of glutathione peroxidase 4 (GPX4), with a DC50, 48h value of 1.68 μM. It induces the accumulation of lipid peroxides and mitochondrial depolarization, subsequently triggering ferroptosis. Additionally, PROTACGPX4 degrader-2 exhibits antiproliferative activity.</p>Formula:C50H61ClN8O9Molecular weight:952.425Anticancer agent 178
<p>Anticanceragent 178 (compound C2) is a potent anticancer compound. It effectively inhibits the proliferation and metabolic activity of MDA-MB 231 cells, with IC50 values of 1.1 and 4.2 μM, respectively. Additionally, Anticanceragent 178 induces ferroptosis and necroptosis in cells.</p>Formula:C32H30ClFeN2O6Molecular weight:629.11418Photosensitizer-5
<p>Photosensitizer-5, a photodynamic agent, exhibits cytotoxicity towards HeLa and HepG2 cells, with IC50 values of 10.4 nM and 6.9 nM, respectively. It induces cell death through lipid peroxidation via an iron-independent ferroptosis pathway. Additionally, Photosensitizer-5 displays antitumor activity in HeLa-tumor-bearing mice.</p>Formula:C35H26BF2IN4O2Color and Shape:SolidMolecular weight:710.32NA-Ir
CAS:<p>NA-Ir is a ferroptosis (Ferroptosis) inducer that targets mitochondrial DNA (mtDNA) and activates the cGAS-STING pathway to stimulate ferritin autophagy (). It also induces the production of reactive oxygen species (ROS) through photodynamic therapy (PDT), depletes glutathione (GSH), and downregulates glutathione peroxidase 4 (GPX4), thereby triggering lipid peroxidation and ferroptosis. NA-Ir exhibits enhanced anticancer activity under light exposure and selectively inhibits cancer cells with high H2S content.</p>Formula:C49H36F6IrN8O4PColor and Shape:SolidMolecular weight:1138.04Pro-GA
CAS:<p>Pro-GA is a cell-permeable γ-glutamylcyclotransferase (γ-GGCT) inhibitor that inhibit proliferation in multiple bladder cancer cell lines. antitumour.</p>Formula:C12H19NO7Color and Shape:SolidMolecular weight:289.28PROTAC NCOA4 degrader-1
<p>PROTACNCOA4 degrader-1 (Compound V3) is a PROTAC-based degrader of NCOA4, exhibiting a DC50 of 3 nM in HeLa cells. Besides acting as a ferroptosis inhibitor, this compound effectively reduces the levels of NCOA4 and decreases intracellular ferrous (Fe2+) levels. Moreover, PROTACNCOA4 degrader-1 ameliorates liver damage in a CCl4-induced acute liver injury model.</p>Color and Shape:Odour SolidZX782
<p>ZX782 acts as a GPX4 protein degrader and an inducer of ferroptosis (Ferroptosis), targeting GPX4 for destruction via both the ubiquitin-proteasome system and the autophagy-lysosome pathway. Following the degradation of GPX4 induced by ZX782, there is a significant increase in the accumulation of lipid reactive oxygen species (ROS) in HT1080 cells.</p>Formula:C39H48ClN5O8Color and Shape:SolidMolecular weight:750.28Ferroptosis Compound Library
<p>A unique collection of 779 ferroptosis signaling pathway related compounds, a powerful tool for new target identification, drug discovery, and mechanism study；</p>Color and Shape:Odour SolidFerroptosis-IN-13
<p>Ferroptosis-IN-13 (compound NY-26) is an inhibitor of ferroptosis. It effectively suppresses RSL3-induced ferroptosis in 786-O cells, with an EC50 value of 62 nM.</p>Formula:C32H30F2N4O3Color and Shape:SolidMolecular weight:556.602GPX4-IN-6
CAS:<p>GPX4-IN-6 is a GPX4 inhibitor with antitumor activity.GPX4-IN-6 induces iron death and is used for the treatment and prevention of triple-negative breast cancer</p>Formula:C18H17BrFNO5Purity:99.54%Color and Shape:SoildMolecular weight:426.23Moracin N
CAS:<p>Moracin N, a ferroptosis inhibitor derived from mulberry leaves, exhibits neuroprotective activity by mitigating oxidative stress [1].</p>Formula:C19H18O4Purity:98%Color and Shape:SolidMolecular weight:310.34Ferroptosis-IN-1
<p>Ferroptosis-IN-1, a diterpene derived from A.</p>Formula:C22H34O5Purity:98%Color and Shape:SolidMolecular weight:378.51-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PE
CAS:<p>Phospholipid with stearic acid and 15(S)-HpETE boosts ferroptosis in MEFs upon GPX4 inhibition.</p>Formula:C43H78NO10PColor and Shape:SolidMolecular weight:800.068Ferroptosis-IN-3
<p>Ferroptosis-IN-3 (Compound 25), a ferroptosis inhibitor, demonstrates potent activity by inhibiting RSL3-induced ferroptosis in HT-1080 cells (EC50: 8.6 nM).</p>Purity:98%Color and Shape:Odour SolidVK-28
CAS:<p>VK-28 is a brain permeable iron chelator with neuroprotection. VK-28 inhibits basal as well as iron-induced mitochondrial lipid peroxidation.</p>Formula:C16H21N3O2Purity:99.87%Color and Shape:SolidMolecular weight:287.36Ferroptosis-IN-14
<p>Ferroptosis-IN-14 (compund 36) exhibits the most potent anti-ferroptotic activity with an EC50 value of 0.58 ± 0.02 μM, demonstrating excellent anti-ferroptotic efficacy, as well as stability in microsomes and plasma.</p>Color and Shape:Odour SolidDTUN
<p>DTUN: lipophilic radical initiator, starts STY-BODIPY liposome co-autoxidization at 0.2 mM, useful in FENIX assays.</p>Color and Shape:Solid2-Acetamidophenol
CAS:<p>2-Acetamidophenol (Orthocetamol) has analgesic and antipyretic effects. 2-Acetamidophenol is an isomer of Paracetamol (4-acetamidophenol).</p>Formula:C8H9NO2Purity:>99.99%Color and Shape:Light Brown PowderMolecular weight:151.16TOFA-Plasmalogen
<p>TOFA-Plasmalogen (compound 1), a derivative of glyceraldehyde, exhibits ferroptosis-inducing properties. This compound promotes lipid peroxidation in cell membranes, leading to cytotoxic effects with an inhibition concentration (IC 50 = 32.87 μM).</p>Formula:C33H62NO7PColor and Shape:SolidMolecular weight:615.82GPX4-IN-14
<p>GPX4-IN-14 (compound 2c) acts as a GPX4 inhibitor, exhibiting both free radical scavenging activity (with a maximum scavenging rate of 72.52%) and anti-tumor proliferation activity in vitro. This compound targets GPX4 protein, elevating lipid peroxide and intracellular Reactive Oxygen Species (ROS) levels, which induces ferroptosis and contributes to its anti-tumor proliferation effects.</p>Formula:C26H39NO8SeColor and Shape:SolidMolecular weight:572.55PROTAC GPX4 degrader-1
CAS:<p>PROTAC GPX4 Degrader-1 (DC-2) is a PROTAC-based compound that efficiently degrades GPX4, demonstrating a degradation concentration (DC 50) of 0.03 μM in HT1080</p>Formula:C50H57ClN10O10Color and Shape:SolidMolecular weight:993.5HDAC-IN-77
<p>HDAC-IN-77 (HL-5s), an HDAC inhibitor, has the capability to induce ferroptosis and suppress the Nrf2/HO-1 signaling pathway. This compound is utilized in cancer research.</p>Formula:C22H26N4O2SColor and Shape:SolidMolecular weight:410.53VEGFR-2-IN-68
<p>VEGFR-2-IN-68 (13b) is an inhibitor of VEGFR-2 with an IC50 value of 41.51 nM. It can induce apoptosis and cause G2/M cell cycle arrest, as well as exhibit anti-cancer metastasis properties.</p>Formula:C27H25N5O2SColor and Shape:SolidMolecular weight:483.1729Ferroptosis-IN-17
<p>Ferroptosis-IN-17 (Compound 18) is an inhibitor of ferroptosis with an EC50 value of 0.57 μM. It effectively reduces the accumulation of intracellular ferrous ions and lipid peroxidation while restoring levels of glutathione (GSH) and glutathione peroxidase 4 (GPX4). In rat plasma, Ferroptosis-IN-17 demonstrates good solubility and notable metabolic stability. This compound holds potential for research in tumor suppression, neurodegenerative diseases, and cardiovascular disorders.</p>Formula:C21H26N4O5SColor and Shape:SolidMolecular weight:446.52Ferumoxytol
CAS:<p>Ferumoxytol is an iron oxide nanoparticle with anti-leukemia properties, specifically against acute myeloid leukemia (AML) cells with low ferroportin (FPN) expression. By increasing intracellular iron levels, Ferumoxytol induces the Fenton reaction to produce reactive oxygen species (ROS), resulting in oxidative stress and ferroptosis. It selectively kills leukemia cells with low FPN expression while sparing normal cells, making it useful for studying leukemia targeting iron metabolism abnormalities.</p>Color and Shape:SolidCQ-ER
<p>CQ-ER is a Coumarin-quinazolinone-based photosensitizer targeting the endoplasmic reticulum (ER). It induces ferroptosis, thereby enhancing photodynamic therapy (PDT).</p>Formula:C33H33N7O6SColor and Shape:SolidMolecular weight:655.72Chalcones A-N-5
CAS:<p>Chalcones A-N-5, a non-cytotoxic trihydroxy chalcone, aids cell growth & neuroprotection, inhibits ferroptosis, and targets AD research.</p>Formula:C21H20N4O4Color and Shape:SolidMolecular weight:392.41UAMC-4821
<p>UAMC-4821 is a ferroptosis inhibitor with an IC50 of 5.2 nM. It effectively scavenges free radicals, inhibits lipid peroxidation, and prevents ML162-induced ferroptosis, providing protective effects on HT-1080 cells. With favorable pharmacokinetic properties in mice, UAMC-4821 presents an oral bioavailability of 63% and demonstrates blood-brain barrier permeability.</p>Formula:C15H19N3OColor and Shape:SolidMolecular weight:257.33PROTAC GPX4 degrader-4
CAS:<p>PROTACGPX4 degrader-4 is a GPX4 PROTAC degrader with a DC50 of 5.32 nM. It inhibits the activity of cancer cell lines RT4, T24, and J82 with IC50 values of 0.09, 2.97, and 7.58 μM, respectively. This compound elevates lipid ROS levels and induces ferroptosis in T24 and RT4 cells. In T24 tumor-bearing BALB/c nude mouse models, PROTACGPX4 degrader-4 demonstrates antitumor activity. It is applicable to bladder cancer research.</p>Formula:C43H58N2O13Color and Shape:SolidMolecular weight:810.93NYY-6a
<p>NYY-6a is a ferroptosis (Ferroptosis) inhibitor, demonstrating significant suppression of RSL3-induced ferroptosis in 786-O and HT-1080 cells, with EC50 values of 52 nM and 50 nM, respectively. As a radical-trapping antioxidant (RTA), NYY-6a effectively reduces lipid peroxidation, comparable to ferrostatin-1 and liproxstatin-1, making it useful for research into ferroptosis-related pathologies.</p>Formula:C23H22N2O3Color and Shape:SolidMolecular weight:374.43GPX4-IN-5
CAS:<p>GPX4-IN-5 is a GPX4 inhibitor with antitumor activity.GPX4-IN-5 induces iron death and may be used for the treatment of triple negative breast cancer.</p>Formula:C18H17ClFNO5Purity:99.58%Color and Shape:SoildMolecular weight:381.78Ferroptosis-IN-16
<p>Ferroptosis-IN-16 (Compound 13l) acts as a specific inhibitor of ferroptosis, demonstrating EC50 values of 0.7 nM in ES-2 cells and 0.9 nM in LX-2 cells. It effectively alleviates acute liver injury induced by Acetaminophen in mouse models and shows excellent metabolic stability in mouse liver microsomes.</p>Formula:C26H23N5OColor and Shape:SolidMolecular weight:421.49W1131 TFA
<p>W1131 TFA is a STAT3 inhibitor and ferroptosis inducer that regulates the IL6-JAK-STAT3 and ferroptosis pathways,gastric cancer.</p>Formula:C25H20F3N5O6Purity:98.1%Color and Shape:SolidMolecular weight:543.45PRLX-93936 HCL
CAS:<p>PRLX-93936 HCL is an analog of erastin and demonstrated synergistic effects against non-small cell lung cancer (NSCLC) cells with cisplatin.</p>Formula:C21H26Cl2N4O2Purity:98.4% - 99.94%Color and Shape:SolidMolecular weight:437.3784-B10
CAS:<p>84-B10 provides protection in cisplatin-induced acute kidney injury, reversing lipid peroxidation accumulation and downregulation of key ferroptosis inhibitors.</p>Formula:C25H22F3NO5Purity:99.76%Color and Shape:SolidMolecular weight:473.44CuATSM
CAS:<p>Cu/Zn-SOD1 enzyme scavenges radicals; mutations cause ALS. Cu-ATSM, crossing blood-brain barrier, targets hypoxic tissue, may aid ALS mice.</p>Formula:C8H14CuN6S2Color and Shape:SolidMolecular weight:321.92Idebenone
CAS:Formula:C19H30O5Purity:>98.0%(T)(HPLC)Color and Shape:Light yellow to Brown powder to crystalMolecular weight:338.44CuATSP
CAS:<p>CuATSP is a potent free radical trapping antioxidant (RTA) and ferroptosis inhibitor inhibit lipid peroxidation, for (ALS) and Parkinson's disease.</p>Formula:C18H18CuN6S2Purity:97.09%Color and Shape:SolidMolecular weight:446.05Cerivastatin sodium
CAS:<p>Cerivastatin sodium (BAY W 6228 sodium) is an HMG-CoA reductase inhibitor with lipid-lowering activity that reduces LDL cholesterol levels.</p>Formula:C26H33FNNaO5Purity:98.50% - 99.67%Color and Shape:SolidMolecular weight:481.53CCW16
CAS:<p>CCW16 is a covalent E3 ubiquitin ligase RNF4 ligand, cysteine reactivity, inducing ferroptosis in AML cells by activating ROS signalling.</p>Formula:C22H20ClNO3Purity:97%Color and Shape:SolidMolecular weight:381.85Chrysosplenetin
CAS:<p>Chrysosplenetin is a metabolic inhibitor of artemisinin.</p>Formula:C19H18O8Purity:97.43% - 98.4%Color and Shape:SolidMolecular weight:374.34L-Glutamic acid monosodium salt
CAS:<p>L-Glutamic acid monosodium salt (MSG) (Monosodium glutamate) is an activator of mGlu1 receptor.</p>Formula:C5H8NO4·NaPurity:99.93%Color and Shape:White Solid CrystallineMolecular weight:169.11Piperlongumine
CAS:<p>Piperlongumine (Piplartine) is a natural alkaloid from Piper longum L.</p>Formula:C17H19NO5Purity:97.03% - 99.90%Color and Shape:SolidMolecular weight:317.34NADPH tetracyclohexanamine
CAS:<p>NADPH tetracyclohexanamine (NADPH (tetracyclohexanamine)) is a cofactor and biological reducing agent.</p>Formula:C45H82N11O17P3Purity:98.73% - 99.05%Color and Shape:SolidMolecular weight:1142.12L-BUTHIONINE-(S,R)-SULFOXIMINE
CAS:<p>L-Buthionine-(S,R)-sulfoximine is a cell-permeable and irreversible inhibitor of γ-glutamylcysteine synthetase that induces oxidative stress by depleting GSH.</p>Formula:C8H18N2O3SPurity:97.07% - ≥98%Color and Shape:White Fine PowderMolecular weight:222.31ML-210
CAS:<p>ML-210 (CID 49766530) is a glutathione peroxidase 4 (GPX4) inhibitor. ML-210 has antitumor activity and induces ferroptosis. Cost-effective and quality-assured.</p>Formula:C22H20Cl2N4O4Purity:97% - 99.03%Color and Shape:SolidMolecular weight:475.32Piperazine Erastin
CAS:<p>Piperazine erastin is an analog of erastin. It causes an iron-dependent form of non-apoptotic cell death termed ferroptosis.</p>Formula:C35H41ClN6O4Purity:99.52%Color and Shape:SolidMolecular weight:645.19RSL3
CAS:<p>View and buy RSL3 from TargetMol.RSL3 is a VDAC-independent ferroptosis activator.Cited in 10 publications.</p>Formula:C23H21ClN2O5Purity:98% - 99.96%Color and Shape:SolidMolecular weight:440.88TBHQ
CAS:<p>TBHQ (tert-Butylhydroquinone) is an antioxidant that induces an antioxidant response through the redox-sensitive transcription factor Nrf2.</p>Formula:C10H14O2Purity:99.17% - 99.53%Color and Shape:White Solid PowderMolecular weight:166.22Trolox
CAS:<p>Trolox is a vitamin E analogue, used in reducing oxidative stress or damage.</p>Formula:C14H18O4Purity:98.90% - 99.90%Color and Shape:White To Fainly Beige Crystalline PowderMolecular weight:250.29Alogliptin
CAS:<p>Alogliptin (SYR-322)(SYR-322) is a potent, selective inhibitor of DPP-4 with IC50 of <10 nM, exhibits greater than 10, 000-fold selectivity over DPP-8 and DPP-9</p>Formula:C18H21N5O2Purity:99.63%Color and Shape:SolidMolecular weight:339.39Alogliptin Benzoate
CAS:<p>Alogliptin Benzoate, a potent DPP-4 inhibitor with >10,000-fold selectivity over DPP-8/9, may also curb TLR-4-induced inflammation.</p>Formula:C25H27N5O4Purity:99.94% - >99.99%Color and Shape:White PowderMolecular weight:461.51WITHAFERIN A
CAS:<p>WITHAFERIN A is a novel class of NFkappaB inhibitors, which hold promise as novel anti-inflammatory agents for treatment of various inflammatory disorders and/</p>Formula:C28H38O6Purity:97.41% - 99.99%Color and Shape:SolidMolecular weight:470.6Bardoxolone Methyl
CAS:<p>Bardoxolone Methyl (TP-155) is a synthetic triterpenoid that acts as an activator of the Nrf2 pathway and an inhibitor of the NF-κB pathway with potential anti-</p>Formula:C32H43NO4Purity:97.81% - 99.09%Color and Shape:SolidMolecular weight:505.69Siramesine hydrochloride
CAS:<p>Siramesine hydrochloride (Lu 28-179 hydrochloride) is a selective sigma-2 receptor agonist, which has been shown to trigger cell death of Y cells and to exhibit</p>Formula:C30H32ClFN2OPurity:99.72% - >99.99%Color and Shape:SolidMolecular weight:491.04Necrostatin-1
CAS:<p>Necrostatin-1 (Nec-1) is a necrotic apoptosis inhibitor and RIP1 inhibitor with specificity.</p>Formula:C13H13N3OSPurity:99.25% - >99.99%Color and Shape:SolidMolecular weight:259.33JKE-1674
CAS:<p>JKE-1674 is an orally active glutathione peroxidase 4 (GPX4) inhibitor and the active metabolite of ML-210.Cost-effective and quality-assured.</p>Formula:C20H20Cl2N4O4Purity:98.02% - 98.4%Color and Shape:SolidMolecular weight:451.3Bay 11-7085
CAS:<p>Bay 11-7085 can irreversibly inhibit the IκBα phosphorylation induced by TNFα (IC50: 10 μM).</p>Formula:C13H15NO2SPurity:99.76% - 99.94%Color and Shape:White SolidMolecular weight:249.33DL-Buthionine-(S,R)-sulfoximine
CAS:<p>DL-Buthionine-(S,R)-sulfoximine (Butionine sulfoximine) is an inhibitor of γ-glutamylcysteine synthetase for the treatment of solid tumors.</p>Formula:C8H18N2O3SPurity:98% - 99.64%Color and Shape:White Fine PowderMolecular weight:222.31Coenzyme Q10
CAS:<p>Coenzyme Q10 (CoQ10) (ubiquinone) is a naturally occurring compound, acting as the electron carrier in the mitochondrial respiratory chain.</p>Formula:C59H90O4Purity:99.14% - 99.88%Color and Shape:DrypowderMolecular weight:863.34ML162
CAS:<p>ML162 is a covalent glutathione peroxidase 4 (GPX4) inhibitor that induces ferroptosis. ML162 has antitumor activity. Cost-effective and quality-assured.</p>Formula:C23H22Cl2N2O3SPurity:98.42% - 99.55%Color and Shape:SolidMolecular weight:477.4(E)-Ferulic acid
CAS:<p>(E)-Ferulic acid ((E)-Coniferic acid) causes the phosphorylation of β-catenin, resulting in proteasomal degradation of β-catenin and increases the expression of</p>Formula:C10H10O4Purity:99.63%Color and Shape:SolidMolecular weight:194.18D-glutamine
CAS:<p>D-glutamine, an D type stereoisomer of glutamine, is one of the 20 amino acids which is encoded by the standard genetic code.</p>Formula:C5H10N2O3Purity:99.99%Color and Shape:White Or Off-White PowderMolecular weight:146.14BAY 87-2243
CAS:<p>BAY 87-2243 is a potent and selective inhibitor of hypoxia-inducible factor-1 (HIF-1).</p>Formula:C26H26F3N7O2Purity:98% - 99.95%Color and Shape:SolidMolecular weight:525.53L-Buthionine-(S,R)-sulfoximine hydrochloride
<p>L-Buthionine-(S,R)-sulfoximine hydrochloride is a fast, irreversible γ-GCS inhibitor that depletes glutathione. IC50: 1.9-29 μM in various tumors.</p>Formula:C8H19ClN2O3SColor and Shape:SolidMolecular weight:258.77Liproxstatin-1 hydrochloride
CAS:<p>Liproxstatin-1 hydrochloride is a high-potency ferroptosis inhibitor capable of effectively preventing ferroptotic cell death, with an IC50 value of 22 nM [1].</p>Formula:C19H22Cl2N4Color and Shape:SolidMolecular weight:377.31Pioglitazone potassium
CAS:<p>Pioglitazone potassium is an oral PPARγ agonist with EC50 of 0.93 μM (human) and 0.99 μM (mouse), used in diabetes research.</p>Formula:C19H19KN2O3SColor and Shape:SolidMolecular weight:394.53CDDO-Im
CAS:<p>CDDO-Im (TP-235) is an activator of Nrf2 and PPAR (Kis: 232/344 nM for PPARα/PPARγ).</p>Formula:C34H43N3O3Purity:98.3% - 99.61%Color and Shape:SolidMolecular weight:541.72(-)-Epicatechin
CAS:<p>(-)-Epicatechin (Epicatechin) is an inhibitor of cyclooxygenase-1 (COX-1), inhibiting the IL-1β-induced expression of iNOS by blocking the nuclear localization</p>Formula:C15H14O6Purity:98.55% - 98.80%Color and Shape:SolidMolecular weight:290.27UAMC-3203 hydrochloride
CAS:<p>UAMC-3203 hydrochloride is a potent and selective Ferroptosis inhibitor with an IC50 of 12 nM.</p>Formula:C25H38ClN5O2SPurity:99.62%Color and Shape:SolidMolecular weight:508.12Baicalein monohydrate
CAS:<p>Baicalein monohydrate blocks 12-lipoxygenase, curbs leukotrienes, lysosomal enzymes, Ca2+ dynamics, and fights arthritis.</p>Formula:C15H12O6Color and Shape:SolidMolecular weight:288.25Ferrostatin-1
CAS:<p>Ferrostatin-1 (Fer-1) is a potent and selective inhibitor of iron death, potently inhibits Erastin-induced iron death in HT-1080 cells. High-Quality, Low-Cost!</p>Formula:C15H22N2O2Purity:96.1% - 99.68%Color and Shape:SolidMolecular weight:262.35CIL56
CAS:<p>CIL56 (CA3) is a small molecule that induces cellular ferroptosis through the production of iron-dependent reactive oxygen species (ROS).</p>Formula:C23H27N3O5S2Purity:99.46% - 99.91%Color and Shape:SolidMolecular weight:489.61Hemin
CAS:<p>Hemin (Hemin chloride) is a chlorinated iron-containing porphyrin, a heme oxygenase (HO)-1 inducer.</p>Formula:C34H32ClFeN4O4Purity:97.169% - 99.59%Color and Shape:Dark Purple Crystalline PowderMolecular weight:651.94DihydroarteMisinic acid
CAS:<p>DihydroarteMisinic acid (Dihydro-Artmisinic Acid) is a natural product from Artemisia annua and the main direct precursor of artemisinin, which is a medicinal</p>Formula:C15H24O2Purity:99.06% - 99.17%Color and Shape:SolidMolecular weight:236.35Arteannuin B
CAS:<p>1. Arteannuin B has potent antimalarial activity.</p>Formula:C15H20O3Purity:98% - 99.8%Color and Shape:SolidMolecular weight:248.32Eprenetapopt
CAS:<p>Eprenetapopt (PRIMA-1Met) restores wild-type conformation and function to mutant p53, and triggers apoptosis in tumor cells.</p>Formula:C10H17NO3Purity:98.75% - 99.57%Color and Shape:SolidMolecular weight:199.25DL-α-Tocopherol
CAS:<p>DL-alpha-Tocopherol (Ephanyl) is a synthetic vitamin E that protects skin fibroblasts from the cytotoxic effects of UV light and has antioxidant properties.</p>Formula:C29H50O2Purity:99.61% - 99.90%Color and Shape:Light Yellow Liquid ViscousMolecular weight:430.71SRS11-92
CAS:<p>SRS11-92 (AA9) is a ferroptosis inhibitor and a derivative of ferrostatin-1</p>Formula:C22H28N2O2Purity:98.58%Color and Shape:SolidMolecular weight:352.47Deferitrin
CAS:<p>Deferitrin (GT-56-252) is an iron chelator. It potentially for the treatment of thalassemia and iron overload.</p>Formula:C11H11NO4SPurity:98.71%Color and Shape:SolidMolecular weight:253.271R,3S-RSL 3
CAS:<p>1R,3S-RSL 3 is a harmala alkaloid.</p>Formula:C23H21ClN2O5Purity:99.51%Color and Shape:SolidMolecular weight:440.88Setanaxib
CAS:<p>Setanaxib (GKT137831) is a potent, specific dual NADPH oxidase (NOX1/4) inhibitor.</p>Formula:C21H19ClN4O2Purity:93.468% - 99.31%Color and Shape:SolidMolecular weight:394.85Dp44mT
CAS:<p>Dp44mT, a effective iron chelator, has selective antitumor activity.</p>Formula:C14H15N5SPurity:99% - 99.02%Color and Shape:SolidMolecular weight:285.37Nordihydroguaiaretic acid
CAS:<p>Nordihydroguaiaretic acid (NDGA) is a natural lipoxygenase (5-LOX) inhibitor. Nordihydroguaiaretic acid has antioxidant effect. Cost-effective and quality-assured.</p>Formula:C18H22O4Purity:97.82% - 99.91%Color and Shape:SolidMolecular weight:302.36NADPH tetrasodium salt
CAS:<p>NADPH tetrasodium salt is the reduced form of the electron acceptor nicotinamide adenine dinucleotide phosphate, which acts as an electron donor in a variety of</p>Formula:C21H26N7Na4O17P3Purity:97.15% - >99.99%Color and Shape:SolidMolecular weight:833.35Troglitazone
CAS:<p>Troglitazone (Romglizone) is a PPARγ agonist with anti-inflammatory and anti-tumor activity.</p>Formula:C24H27NO5SPurity:98% - 99.8%Color and Shape:Yellow SolidMolecular weight:441.54SRS16-86
CAS:<p>SRS16-86 is a novel third-generation ferrostatin, is an inhibitor of ferroptosis.</p>Formula:C26H32N4O2Purity:97.73%Color and Shape:SolidMolecular weight:432.56Pseudolaric Acid B
CAS:<p>Pseudolaric acid B, a natural diterpenoid compound, is isolated from Pseudolarix kaempferi.</p>Formula:C23H28O8Purity:98.91% - 99.84%Color and Shape:SolidMolecular weight:432.46Levobupivacaine
CAS:<p>Levobupivacaine is an amino-amide local anaesthetic drug belonging to the family of n-alkylsubstituted pipecoloxylidide.</p>Formula:C18H28N2OPurity:99.72%Color and Shape:SolidMolecular weight:288.43Liproxstatin-1
CAS:<p>Liproxstatin-1 is a potent and selective inhibitor of iron death (IC50=22 nM).</p>Formula:C19H21ClN4Purity:97.11% - 99.44%Color and Shape:SolidMolecular weight:340.85Rosiglitazone hydrochloride
CAS:<p>Rosiglitazone hydrochloride (BRL-49653 HCl) is a blood glucose-lowering drugs, stimulating insulin secretion by binding to the PPAR receptors in fat cells.</p>Formula:C18H19N3O3S·HClPurity:99.63% - 99.79%Color and Shape:SolidMolecular weight:393.89SP600125
CAS:<p>SP600125 (JNK Inhibitor II) is a JNK inhibitor that inhibits JNK1, JNK2, and JNK3 (IC50=40/40/90 nM) with oral potency, reversibility, and ATP-competitive</p>Formula:C14H8N2OPurity:97.63% - 99.82%Color and Shape:SolidMolecular weight:220.23L-Cystine
CAS:<p>L-Cystine (Cystine Acid) is not considered one of the 20 amino acids, L-Cystine (Cystine Acid) is a sulfur-containing derivative obtained from oxidation of</p>Formula:C6H12N2O4S2Purity:99.59% - 99.85%Color and Shape:White Solid PowderMolecular weight:240.30Rosiglitazone
CAS:<p>Rosiglitazone (BRL49653) is a PPARγ agonist, TRPC5 activator, and TRPM3 inhibitor with oral activity.</p>Formula:C18H19N3O3SPurity:98.61% - 99.87%Color and Shape:White To Off-White Crystalline PowderMolecular weight:357.43L-Glutamic acid
CAS:<p>L-Glutamic acid is an agonist of glutamate receptors, including metabotropic glutamate receptors (mGluR), AMPA, NMDA, and KA. High-Quality, Low-Cost!</p>Formula:C5H9NO4Purity:99.14% - 99.55%Color and Shape:White Solid CrystallineMolecular weight:147.13ML385
CAS:<p>ML385 is an NRF2 inhibitor (IC50=1.9 μM) with novelty and specificity.</p>Formula:C29H25N3O4SPurity:98.08% - >99.99%Color and Shape:SolidMolecular weight:511.59Trigonelline
CAS:<p>Trigonelline (Trigenolline), an alkaloid with potential antidiabetic activity, is present in considerable amounts in coffee.</p>Formula:C7H7NO2Purity:97.585% - 99.49%Color and Shape:Prisms Aqueous From Alcohol + Water SolidMolecular weight:137.14PRIMA-1
CAS:<p>PRIMA-1 (NSC-281668) is a mutant p53 reactivator. It induces apoptosis and inhibits growth of human tumors with mutant p53.</p>Formula:C9H15NO3Purity:99.22%Color and Shape:SolidMolecular weight:185.22Atorvastatin hemicalcium salt
CAS:<p>Atorvastatin hemicalcium salt (Atorvastatin Calcium) is an orally HMG-CoA reductase inhibitor that lowers cholesterol. Cost-effective and quality-assured.</p>Formula:C33H34FN2O5CaPurity:99.27% - >99.99%Color and Shape:White Crystalline PowderMolecular weight:577.67Erastin
CAS:<p>Erastin is an iron death activator that acts on the mitochondrial VDAC in a ROS- and iron-dependent manner, anti-tumor. High-Quality, Low-Cost!</p>Formula:C30H31ClN4O4Purity:98% - 99.75%Color and Shape:SolidMolecular weight:547.04FIN56
CAS:<p>FIN56 is a specific inducer of ferroptosis.</p>Formula:C25H31N3O5S2Purity:99.72% - 99.78%Color and Shape:SolidMolecular weight:517.66PD146176
CAS:<p>PD146176 (NSC-168807) is an inhibitor of 15-Lipoxygenase (15-LO) , it inhibits rabbit reticulocyte 15-LO with Ki of 197 nM and IC50 of 0.54 μM.</p>Formula:C15H11NSPurity:98.00%Color and Shape:SolidMolecular weight:237.32Pifithrin-α hydrobromide
CAS:<p>Pifithrin-α hydrobromide (Pifithrin-α hydrobromide) is a p53 inhibitor, inhibiting p53-dependent transactivation of p53-responsive genes.</p>Formula:C16H18N2OS·HBrPurity:97.71% - >99.99%Color and Shape:SolidMolecular weight:367.3Pifithrin-β hydrobromide
CAS:<p>Pifithrin-β hydrobromide (Cyclic PFT-α) is an inhibitor of p53; reversibly blocks p53-dependent transcriptional activation and apoptosis.</p>Formula:C16H17BrN2SPurity:99.24% - 99.74%Color and Shape:SolidMolecular weight:349.29Levobupivacaine hydrochloride
CAS:<p>Levobupivacaine hydrochloride ((S)-(-)-Bupivacaine monohydrochloride) is a reversible neuronal sodium channel inhibitor, used as a long-acting local anesthetic.</p>Formula:C18H28N2O·HClPurity:99.74%Color and Shape:White Crystalline PowderMolecular weight:324.89Ammonium iron(III) citrate
CAS:<p>Ammonium iron(III) citrate (Ferric ammonium citrate) is a physiological form of non-ferritin-bound iron that causes intracellular iron overload and iron death.</p>Formula:C24H32Fe3N3O28Purity:98%Color and Shape:Ferric Ammonium Citrate Is A Yellowish Brown To Red Solid With A Faint Odor Of AmmoniaMolecular weight:978.05U-73122
CAS:<p>U-73122 (U73122) , an effective PLC inhibitor, reduces agonist-induced Ca2+ increases in platelets and PMN.</p>Formula:C29H40N2O3Purity:97.50%Color and Shape:Solid Off-WhiteMolecular weight:464.64UAMC-3203
CAS:<p>UAMC-3203 is a potent and selective Ferroptosis inhibitor (IC50: 12 nM).</p>Formula:C25H37N5O2SPurity:97.052% - 99.72%Color and Shape:SolidMolecular weight:471.66FINO2
CAS:<p>FINO2, a strong ferroptosis trigger, blocks GPX4, oxidizes Fe2+, stable in different pH, causes lipid peroxidation.</p>Formula:C15H28O3Purity:97.27%Color and Shape:SoildMolecular weight:256.38Microtubule inhibitor 8
CAS:<p>Microtubule Inhibitor 8 (MP-HJ-1b) serves as a potent disruptor of microtubule function, inducing cell death via ferroptosis and demonstrating anti-tumor effects [1] [2].</p>Formula:C21H15N3O2SColor and Shape:SolidMolecular weight:373.43Pioglitazone-d4
CAS:<p>Pioglitazone D4 is a deuterium labeled Pioglitazone. Pioglitazone is a agonist of PPARγ .</p>Formula:C19H20N2O3SPurity:98%Color and Shape:SolidMolecular weight:360.46W1131
CAS:<p>W1131 is a potent STAT3 inhibitor and ferroptosis trigger, reducing cancer progression and 5-FU resistance.</p>Formula:C23H19N5O4Color and Shape:SolidMolecular weight:429.43YL-939
<p>YL-939 is a potent inhibitor of ferroptosis, targeting the PHB2/ferritin/iron axis to impede this form of cell death.</p>Formula:C25H26N6OColor and Shape:SolidMolecular weight:426.51Ferroptosis inducer-1
CAS:<p>Ferroptosis inducer-1 is a Ferroptosis inducer with antitumor potential .</p>Formula:C25H21ClN2O5Color and Shape:SolidMolecular weight:464.9CN128 hydrochloride
CAS:<p>CN128 hydrochloride is an oral, selective hydroxypyridone iron chelator for β-thalassemia research.</p>Formula:C15H18ClNO3Color and Shape:SolidMolecular weight:295.76Anticancer agent 147
CAS:<p>Compound 6j (Anticancer agent 147), a sophoridine derivative and ferroptosis inducer, promotes intracellular accumulation of Fe2+, reactive oxygen species (ROS</p>Formula:C32H40BrN3O2Purity:98%Color and Shape:SolidMolecular weight:578.58Tubulin inhibitor 30
CAS:<p>Tubulin Inhibitor 30, exhibiting an IC50 value of 0.52 μM, functions as an inhibitor of tubulin assembly. Additionally, it can induce ferroptosis.</p>Formula:C22H19N3O5Color and Shape:SolidMolecular weight:405.4IM-93
CAS:<p>IM-93 inhibits ferroptosis and NETosis with an IC< sub>50 of 0.45 μM for cell death inhibition [1].</p>Formula:C21H28N4O2Color and Shape:SolidMolecular weight:368.47CGP 65015
CAS:<p>CGP 65015 is an oral iron chelator and can mobilize iron deposits.</p>Formula:C14H15NO4Purity:98%Color and Shape:SolidMolecular weight:261.27FA16
<p>FA16 is a selective, metabolically stable ferroptosis inducer with an IC50 value of 1.26 μM.FA16 is a derivative of 2-(trifluoromethyl)benzimidazole.FA16</p>Formula:C22H27F3N4O2SPurity:99.44%Color and Shape:SolidMolecular weight:468.54Deferitazole
CAS:<p>Deferitazole (FBS 0701) is a novel and orally active, selective and high affinity iron chelator.</p>Formula:C18H25NO7SPurity:99.48%Color and Shape:SolidMolecular weight:399.46Erastin2
CAS:<p>Erastin2 is an iron death inducer that induces cell death by binding to the lipophilic free radical trapping antioxidant ferrostatin-1 or the iron chelator DFO.</p>Formula:C36H35ClN4O4Purity:99.63%Color and Shape:SolidMolecular weight:623.14HBED
CAS:<p>HBED (CHELII) is an iron chelator and can be used in research on the treatment of chronic iron overload and acute iron poisoning.</p>Formula:C20H24N2O6Purity:97.35% - 98.58%Color and Shape:SolidMolecular weight:388.41BCP-T.A
CAS:<p>BCP-T.A is an iron death inducer that acts by binding to GPX4.</p>Formula:C23H19Cl2N3OSPurity:99.49%Color and Shape:SolidMolecular weight:456.39Lepadin E
CAS:<p>Lepadin E, a notably cytotoxic compound, effectively stimulates ferroptosis via the canonical p53-SLC7A11-GPX4 pathway.</p>Formula:C26H47NO3Purity:98%Color and Shape:SolidMolecular weight:421.66CP-24879 hydrochloride
CAS:<p>CP-24879 HCl, a Δ5D/Δ6D dual-inhibitor, reduces liver lipid buildup and inflammation.</p>Formula:C11H18ClNOPurity:98.08%Color and Shape:SolidMolecular weight:215.72Docebenone
CAS:<p>Docebenone is a selective and orally active inhibitor of 5-LO.</p>Formula:C21H26O3Color and Shape:SolidMolecular weight:326.43Ferroptocide
CAS:<p>Ferroptocide is a thioredoxin inhibitor that induces iron death in cancer cells and can be used in breast cancer research.</p>Formula:C30H36ClN3O7Color and Shape:SolidMolecular weight:586.08Ogremorphin
CAS:<p>Ogremorphin (GPR68-IN-1) is a potent inhibitor of GPR68, exhibiting an EC50 of 170 nM.it is utilized in the study of autoimmune chronic inflammatory diseases [1</p>Formula:C21H17N3OSPurity:99.65% - 99.65%Color and Shape:SolidMolecular weight:359.44Lepadin H
CAS:<p>Lepadin H, a marine alkaloid and ferroptosis inducer, exhibits significant cytotoxicity by promoting p53 expression, escalating ROS production, and enhancing</p>Formula:C26H45NO3Purity:98%Color and Shape:SolidMolecular weight:419.64viFSP1
CAS:<p>viFSP1, a species-independent FSP1 inhibitor, effectively induces ferroptosis in FSP1-dependent cells by targeting the highly conserved NAD(P)H binding pocket of FSP1, directly inhibiting its activity. This action results in lipid peroxidation and exhibits anticancer activity [1].</p>Formula:C16H17N3O3SColor and Shape:SolidMolecular weight:331.39
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