GPCR/G-Protein
GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.
Subcategories of "GPCR/G-Protein"
- 5-HT Receptor(942 products)
- Adenosine Receptor(242 products)
- Adrenergic Receptor(2,949 products)
- Bombesin Receptor(30 products)
- Bradykinin Receptor(59 products)
- CXCR(149 products)
- CaSR(32 products)
- Cannabinoid Receptor(195 products)
- Dopamine Receptor(410 products)
- Endothelin Receptor(75 products)
- GNRH Receptor(73 products)
- GPCR19(31 products)
- GRK(32 products)
- GTPase(21 products)
- Glucagon Receptor(166 products)
- Hedgehog/Smoothened(45 products)
- Histamine Receptor(359 products)
- LPA Receptor(21 products)
- Melatonin Receptor(24 products)
- OX Receptor(40 products)
- Opioid Receptor(298 products)
- PAFR(11 products)
- PKA(49 products)
- S1P Receptor(17 products)
- SGLT(30 products)
- Sigma receptor(46 products)
Show 18 more subcategories
Found 5378 products of "GPCR/G-Protein"
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Amiselimod hydrochloride
CAS:<p>Amiselimod hydrochloride (MT-1303 hydrochloride) is a sphingosine 1-phosphate receptor-1 (S1P1) modulator.</p>Formula:C19H31ClF3NO3Purity:99.55%Color and Shape:SolidMolecular weight:413.9Acetophenazine dimaleate
CAS:<p>Acetophenazine dimaleate is an antipsychotic agent, effective in anxious depression. Acetophenazine dimaleate primarily targets the dopamine D2 receptor.</p>Formula:C31H37N3O10SPurity:99.39% - 99.48%Color and Shape:SolidMolecular weight:643.71Cetirizine dihydrochloride
CAS:Cetirizine dihydrochloride is a potent non-drowsy antihistamine for allergies and asthma.Formula:C21H27Cl3N2O3Purity:99.4% - 99.97%Color and Shape:SolidMolecular weight:461.81CP-809101 hydrochloride
CAS:<p>CP-809101 hydrochloride is a potent and selective 5-HT2C receptor agonist (pEC50: 9.96/7.19/6.81 for human 5-HT2C/5-HT2B/5-HT2A receptors).</p>Formula:C15H18Cl2N4OPurity:99.5%Color and Shape:SolidMolecular weight:341.24Alfuzosin hydrochloride
CAS:<p>Alfuzosin hydrochloride (Alfuzosin HCl) is an α1 adrenergic receptor antagonist. It applies to treat benign prostatic hyperplasia (BPH).</p>Formula:C19H27N5O4·HClPurity:99.78%Color and Shape:White To Off-White SolidMolecular weight:425.91Urapidil hydrochloride
CAS:<p>Urapidil hydrochloride (Urapidil HCl) is 5-HT1A receptor agonist and an α1-adrenoceptor antagonist.</p>Formula:C20H29N5O3·HClPurity:99.58%Color and Shape:White Or Off-White Crystalline PowderMolecular weight:423.94KGA-2727
CAS:<p>KGA-2727: potent, selective SGLT1 inhibitor (human Ki 97.4 nM, rat 43.5 nM), with high selectivity over SGLT2 for diabetes treatment.</p>Formula:C26H40N4O8Purity:98.46%Color and Shape:SolidMolecular weight:536.62Promazine hydrochloride
CAS:Promazine hydrochloride, a phenothiazine less potent than chlorpromazine, treats disturbed behavior and nausea.Formula:C17H21ClN2SPurity:99.90%Color and Shape:SolidMolecular weight:320.88Urocortin (rat) acetate
Urocortin (rat) acetate: CRF receptor agonist; Ki=13nM (hCRF1), 1.5nM (rCRF2α), 0.97nM (mCRF2β); neuropeptide.Purity:97.76%Color and Shape:SoildChlorprothixene hydrochloride
CAS:Chlorprothixene hydrochloride, a typical antipsychotic, blocks 5-HT2, D1-D3, H1, muscarinic, and alpha1 receptors.Formula:C18H18ClNS·HClPurity:99.76%Color and Shape:White PowderMolecular weight:352.32CYM 50769
CAS:<p>CYM 50769 is a neuropeptide W/B receptor 1 (NPBWR1, GPR7) antagonist(IC50 = 0.12 μM).</p>Formula:C24H17ClN2O3Purity:98% - 99.08%Color and Shape:SolidMolecular weight:416.86hGPR91 antagonist 1
CAS:<p>hGPR91 antagonist 1 is a potent and selective hGPR91 antagonist (IC50: 7 μM).</p>Formula:C31H23F4N3OPurity:98.89%Color and Shape:SolidMolecular weight:529.53PF429242 dihydrochloride
CAS:<p>PF429242 dihydrochloride can reversibly inhibit S1P (IC50 of 175 nM).</p>Formula:C25H37Cl2N3O2Purity:99.68%Color and Shape:SolidMolecular weight:482.49Prucalopride
CAS:<p>Prucalopride (R-93877), a selective 5-HT4A/4B agonist (Ki: 2.5/8 nM), is >290x more specific for these receptors.</p>Formula:C18H26ClN3O3Purity:>99.99%Color and Shape:SolidMolecular weight:367.87Fluvoxamine maleate
CAS:<p>Fluvoxamine maleate (DU-23000 (maleate)) is a selective serotonin reuptake inhibitor that is used in the treatment of depression and a variety of anxiety</p>Formula:C19H25F3N2O6Purity:99.92% - 99.94%Color and Shape:White Crystalline PowderMolecular weight:434.41Cyproheptadine hydrochloride sesquihydrate
CAS:<p>Cyproheptadine hydrochloride sesquihydrate (Peritol), an antihistamine, is an antagonist of serotonin and histamine2.</p>Formula:C21H24ClNOPurity:99.77% - >99.99%Color and Shape:White To Slightly Yellowish Crystalline SolidMolecular weight:341.88Zolmitriptan
CAS:<p>Zolmitriptan targets 5-HT 1B/1D receptors, constricts cranial vessels, inhibits pain signals, and stops pro-inflammatory neuropeptides, alleviating migraines.</p>Formula:C16H21N3O2Purity:99.69% - 99.91%Color and Shape:White Or Kind Of White PowderMolecular weight:287.36Ziprasidone hydrochloride
CAS:<p>Ziprasidone hydrochloride (CP-88059 hydrochloride) is a united 5-HT (serotonin) and dopamine receptor antagonist which shows potent effects of antipsychotic</p>Formula:C21H22CL2N4OSPurity:97.97% - 99.82%Color and Shape:SolidMolecular weight:449.4Olinciguat
CAS:<p>Olinciguat (IW-1701) is an oral guanylate cyclase (sGC) stimulator.</p>Formula:C21H16F5N7O3Purity:99.33% - 99.71%Color and Shape:SolidMolecular weight:509.39YNT-185
CAS:<p>YNT-185 is a nonpeptide, selective agonist of the orexin type-2 receptor (OX2R), demonstrating EC50 values of 0.028 μM and 2.75 μM for OX2R and OX1R,</p>Formula:C33H37N5O5SPurity:99.67%Color and Shape:SolidMolecular weight:615.74Dopexamine hydrochloride
CAS:<p>Dopexamine hydrochloride (FPL60278AR) is a β2-adrenoceptor agonist that modulates inflammation and protects organs without affecting hemodynamics.</p>Formula:C22H34Cl2N2O2Purity:98.55%Color and Shape:SolidMolecular weight:429.42Ketanserin
CAS:Ketanserin: quinazoline derivative, 5-HT2 receptor antagonist, may lower blood pressure and inhibit blood clots.Formula:C22H22FN3O3Purity:99.19% - 99.73%Color and Shape:SolidMolecular weight:395.43Alverine citrate
CAS:<p>Alverine citrate (NSC 35459) is utilized in functional gastrointestinal disorders.</p>Formula:C26H35NO7Purity:98.53% - 99.43%Color and Shape:CoaMolecular weight:473.57Ondansetron hydrochloride dihydrate
CAS:<p>Ondansetron hydrochloride dihydrate (GR 38032) is a competitive serotonin type 3 receptor antagonist,which has reported anxiolytic and neuroleptic properties.</p>Formula:C18H19N3O·HCl·2H2OPurity:99.92%Color and Shape:White Crystal PowderMolecular weight:365.86Pizotifen
CAS:<p>Pizotifen is a serotonin antagonist with mild anticholinergic effects, used in migraine prevention. Not available in the USA.</p>Formula:C19H21NSPurity:99.93%Color and Shape:SolidMolecular weight:295.44ML-180
CAS:<p>ML-180 (SR1848) is a potent orphan nuclear receptor liver receptor homolog 1 (LRH-1; NR5A2) inverse agonist (IC50 of 3.7 μM) .</p>Formula:C20H25ClN4O2Purity:99.74%Color and Shape:SolidMolecular weight:388.89Nylidrin hydrochloride
CAS:<p>Nylidrin HCl inhibits IgG1-induced histamine release in guinea pigs and IgE-induced release in rat mast cells & human basophils.</p>Formula:C19H26ClNO2Purity:99.35%Color and Shape:SolidMolecular weight:335.87JNJ-18038683
CAS:<p>JNJ-18038683 is a 5-Hydroxytryptamine Type 7 (5-HT7) receptor antagonist, with pKis of 8.19, 8.20 for rat and human 5-HT7 in HEK293 cells, respectively.</p>Formula:C26H28ClN3O7Purity:97.29%Color and Shape:SolidMolecular weight:529.97Talastine
CAS:<p>Talastine is an antihistamine compound that can induce an allergic rash.</p>Formula:C19H21N3OPurity:98.50% - 99.44%Color and Shape:SolidMolecular weight:307.39Lafutidine
CAS:<p>Lafutidine (FRG-8813) is a newly developed histamine H(2)-receptor antagonist, which can inhibit gastric acid secretion.</p>Formula:C22H29N3O4SPurity:98.55%Color and Shape:Yellowish White Crystalline PowderMolecular weight:431.55Clonidine hydrochloride
CAS:Clonidine hydrochloride (Catapres) is a centrally active α-adrenergic agonist used predominantly as an antihypertensive agent.Formula:C9H10Cl3N3Purity:99.16% - 99.86%Color and Shape:SolidMolecular weight:266.55Rimonabant
CAS:<p>Rimonabant (SR141716) is an inverse agonist for the cannabinoid receptor CB1.</p>Formula:C22H21Cl3N4OPurity:98% - 99.91%Color and Shape:White Or Almost White Crystalline PowderMolecular weight:463.79Silodosin
CAS:Silodosin (KAD 3213) is an alpha-Adrenergic Blocker. The mechanism of action of silodosin is as an Adrenergic alpha-Antagonist.Formula:C25H32F3N3O4Purity:99.282% - 99.76%Color and Shape:Colorless To Pink SolidMolecular weight:495.53Metaproterenol hemisulfate
CAS:<p>Metaproterenol hemisulfate (Orciprenaline sulfate) is a beta-2 adrenergic agonist used in the treatment of ASTHMA and BRONCHIAL SPASM.</p>Formula:C11H17NO3·5H2O4SPurity:98.53% - 99.74%Color and Shape:SolidMolecular weight:260.3Fluparoxan hydrochloride
CAS:<p>Fluparoxan hydrochloride is a highly selective and potent α2-adrenoceptor antagonist for the prevention, amelioration or treatment of neurodevelopmental</p>Formula:C10H11ClFNO2Purity:99.98%Color and Shape:SoildMolecular weight:231.65Levosulpiride
CAS:<p>Levosulpiride (S-(-)-Sulpiride) is the (S)-enantiomer of sulpiride, which is a D2 receptor antagonist, an atypical antipsychotic drug of the benzamide class.</p>Formula:C15H23N3O4SPurity:98.20% - 99.88%Color and Shape:White Crystalline PowderMolecular weight:341.43Venlafaxine hydrochloride
CAS:<p>Venlafaxine HCl, a cyclohexanol phenethylamine, acts as an SNRI antidepressant.</p>Formula:C17H28ClNO2Purity:97.32% - 99.86%Color and Shape:White Crystalline PowderMolecular weight:313.86Noradrenaline bitartrate
CAS:<p>Norepinephrine bitartrate acts directly on the α- and β-adrenergic receptors.</p>Formula:C12H19NO10Purity:99.53% - >99.99%Color and Shape:SolidMolecular weight:337.28Aripiprazole
CAS:Aripiprazole (OPC-14597) is a piperazine/quinolone antipsychotic, partial agonist at 5-HT1A/D2, and antagonist at 5-HT2A.Formula:C23H27Cl2N3O2Purity:99.43% - 99.62%Color and Shape:Colourless Flake Crystalline SolidMolecular weight:448.39(3aR,9aR)-Fluparoxan
CAS:<p>(3aR,9aR)-Fluparoxan is a highly selective and potent adrenergic receptor α2B antagonist for the prevention, amelioration or treatment of neurodevelopmental</p>Formula:C10H10FNO2Purity:97.82%Color and Shape:SoildMolecular weight:195.19AH 6809
CAS:<p>AH 6809 blocks EP1, EP2, EP3, DP receptors (Ki: 1217-1597 nM human, 350 nM mouse EP2).</p>Formula:C17H14O5Purity:97.59%Color and Shape:SolidMolecular weight:298.29Phenothiazine
CAS:<p>Phenothiazine (ENT 38) is a class of agents exhibiting antiemetic, antipsychotic, antihistaminic, and anticholinergic activities.</p>Formula:C12H9NSPurity:99.95%Color and Shape:Yellow Solid PelletsMolecular weight:199.27(R)-Elagolix
CAS:<p>(R)-Elagolix (NBI-56418) is an orally active, highly selective, short-term potent antagonist of the non-peptide gonadotropin-releasing hormone receptor.</p>Formula:C32H30F5N3O5Purity:99.08%Color and Shape:SolidMolecular weight:631.59Indacaterol maleate
CAS:<p>Indacaterol maleate (QAB149) is an ultra-long-acting β-adrenoceptor agonist.</p>Formula:C28H32N2O7Purity:99.03% - 99.67%Color and Shape:SolidMolecular weight:508.56Moxisylyte hydrochloride
CAS:Moxisylyte hydrochloride (Thymoxamine hydrochloride) is an alpha-adrenergic blocking agent that is used in Raynaud's disease.Formula:C16H26ClNO3Purity:99.94% - ≥95%Color and Shape:SolidMolecular weight:315.842-Bromo-6-methoxynaphthalene
CAS:<p>2-Bromo-6-methoxynaphthalene was used in the synthesis of nabumetone [4-(6-methoxy-2-naphthalenyl)-2-butanone] by Heck reaction.</p>Formula:C11H9BrOPurity:98.51%Color and Shape:White To Off-White PowderMolecular weight:237.09Roxatidine Acetate hydrochloride
CAS:<p>Roxatidine Acetate hydrochloride (HOE 760) is a specific and competitive histamin H2-receptor antagonist. Roxatidine inhibits gastric acid secretion.</p>Formula:C19H29ClN2O4Purity:99.49%Color and Shape:SolidMolecular weight:384.9Methyldopa
CAS:<p>Methyldopa (MK-351), an alpha-adrenergic agonist (selective for α2-adrenergic receptors) psychoactive medicine, is served as an antihypertensive or</p>Formula:C10H13NO4Purity:98.95% - 99.86%Color and Shape:Less Or Almost Colorless Crystals Or White To Yellowish-White FineMolecular weight:211.21Filorexant
CAS:<p>Filorexant (MK-6096) is an orally bioavailable effective and selective reversible antagonist of OX1 and OX2 receptor with (Ki <3 nM).</p>Formula:C24H25FN4O2Purity:98.88%Color and Shape:SolidMolecular weight:420.48Granisetron hydrochloride
CAS:<p>Granisetron hydrochloride (Granisetron HCl) is a serotonin receptor (5HT-3 selective) antagonist that has been used as an antiemetic for cancer chemotherapy</p>Formula:C18H25ClN4OPurity:99.88% - 99.93%Color and Shape:White To Off-White Crystalline SolidMolecular weight:348.87
