Potassium Channel
Potassium channels are a diverse group of membrane proteins that facilitate the flow of potassium ions (K+) across the cell membrane. These channels play a crucial role in maintaining the resting membrane potential, regulating cell volume, and controlling the excitability of neurons and muscle cells. Potassium channels are involved in various physiological processes, including cardiac rhythm regulation, insulin secretion, and neurotransmitter release. Dysregulation of potassium channels is linked to conditions such as arrhythmias, epilepsy, and hypertension. At CymitQuimica, we offer a wide range of potassium channel modulators to support your research in electrophysiology, cardiovascular health, and neurobiology.
Found 276 products of "Potassium Channel"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Nicorandil
CAS:<p>Nicorandil (SG-75)(Ikorel) acts by relaxing the smooth muscle of the blood vessels, especially those of the venous system.</p>Formula:C8H9N3O4Purity:98.14% - >99.99%Color and Shape:White Or Off-White PowderMolecular weight:211.17Oxybutynin chloride
CAS:<p>Oxybutynin chloride (Oxybutynin HCl) is an anticholinergic medication used to relieve urinary and bladder difficulties.</p>Formula:C22H32ClNO3Purity:99.27% - >99.99%Color and Shape:White PowderMolecular weight:393.96Ropivacaine
CAS:<p>Ropivacaine (LEA-103 HCl) is a local anaesthetic drug belonging to the amino amide group.</p>Formula:C17H26N2OPurity:97.75% - >99.99%Color and Shape:SolidMolecular weight:274.40Oxybutynin
CAS:<p>Oxybutynin (Ditropan) is a synthetic anticholinergic agent that is used for treatment of urinary incontinence and overactive bladder syndrome.</p>Formula:C22H31NO3Purity:97.81% - 99.57%Color and Shape:White To Off-White Crystalline PowderMolecular weight:357.49Butamben
CAS:<p>Butamben (Butyl 4-aminobenzoate) is a long-duration local anesthetic used for the treatment of chronic pain.</p>Formula:C11H15NO2Purity:99.43%Color and Shape:Crystals From Alc Physical Description Yellow Powder Insoluble In Water (Ntp 1992)Molecular weight:193.24Mefloquine
CAS:<p>Mefloquine (Ro 215998), a quinoline antimalarial agent, is an anti-SARS-CoV-2 entry inhibitor.</p>Formula:C17H16F6N2OPurity:99.89%Color and Shape:SolidMolecular weight:378.31N-Acetylprocainamide
CAS:<p>N-Acetylprocainamide (NAPA), the N-acetylated metabolite of Procainamide, is a Class III antiarrhythmic agent, while procainamide is a Class Ia antiarrhythmic</p>Formula:C15H23N3O2Purity:99.65% - 99.74%Color and Shape:SolidMolecular weight:277.36VU591 hydrochloride
CAS:<p>VU591 hydrochloride is a selective Kir1.1 (ROMK) blocker with IC50 of 0.24 μM, not affecting Kir7.1, Kir2.1, Kir2.3, or Kir4.1, similar to VU 590.</p>Formula:C16H13ClN6O5Purity:98.93% - 99.22%Color and Shape:SolidMolecular weight:404.76Ifenprodil Tartrate
CAS:<p>Ifenprodil is a selective NMDA receptor (glutamate) antagonist.</p>Formula:C21H27NO2C4H6O6Purity:99.02% - 99.55%Color and Shape:SolidMolecular weight:400.49NS8593 hydrochloride
CAS:<p>NS8593 hydrochloride (NS8593 HCl) is a potent and selective inhibitor of small conductance Ca2+-activated K+ channels (SK channels) .</p>Formula:C17H18ClN3Purity:99.77%Color and Shape:SolidMolecular weight:299.8Bupivacaine hydrochloride
CAS:<p>Bupivacaine hydrochloride (Vivacaine) is a long-lasting, amide local anesthetic that blocks sodium channels, inhibiting nerve impulses and sensation.</p>Formula:C18H28N2O·HClPurity:99.9% - >99.99%Color and Shape:SolidMolecular weight:324.89Astemizole
CAS:<p>Astemizole (Laridal) is a long-acting antihistamine for allergies like rhinitis and asthma, with fewer anticholinergic effects.</p>Formula:C28H31FN4OPurity:98.24% - 99.67%Color and Shape:White Crystals SolidMolecular weight:458.57Rosuvastatin calcium
CAS:<p>Rosuvastatin calcium (ZD4522) , a selective and competitive inhibitor of hepatic hydroxymethyl-glutaryl coenzyme A (HMG-CoA) reductase, has antilipidemic</p>Formula:(C22H27FN3O6S)CaPurity:98.21% - 99.68%Color and Shape:White To Off-White Crystalline SolidMolecular weight:1001.14Quinidine hydrochloride monohydrate
CAS:<p>Quinidine hydrochloride monohydrate is an optical isomer of quinine. Quinidine prolongs cellular action potential and decreases automaticity.</p>Formula:C20H27ClN2O3Purity:94.4% - 99.68%Color and Shape:SolidMolecular weight:378.89Dequalinium chloride
CAS:<p>Dequalinium chloride: topical bacteriostat, blocks apamin-sensitive K+ channels, used for wounds, oral infections, potential antifungal, risk of skin ulcers.</p>Formula:C30H40Cl2N4Purity:99.79% - 99.9%Color and Shape:SolidMolecular weight:527.59Minoxidil
CAS:<p>Minoxidil (U10858) is an orally administered vasodilator with hair growth stimulatory and antihypertensive effects.</p>Formula:C9H15N5OPurity:99.885% - >99.99%Color and Shape:Crystals From Methanol-Acetonitrile SolidMolecular weight:209.251-EBIO
CAS:<p>1-EBIO (1-EBIO) is a calium channel agonist.</p>Formula:C9H10N2OPurity:98.75%Color and Shape:SolidMolecular weight:162.19Linoleoyl glycine
CAS:<p>Linoleoyl glycine activates hKCNQ1/hKCNE1 channels, has analgesic properties, and is found in skin, spinal cord, and brain.</p>Formula:C20H35NO3Purity:98.96%Color and Shape:SolidMolecular weight:337.5Topiramate
CAS:<p>Topiramate (RWJ 17021) is a unique antiseizure medication that is used in the treatment of partial and generalized seizures.</p>Formula:C12H21NO8SPurity:99.79% - 99.92%Color and Shape:White To Off-White Crystalline PowderMolecular weight:339.36NS3623
CAS:<p>NS3623 is an activator of human ether-a-go-go-related gene potassium channels.</p>Formula:C15H10BrF3N6OPurity:97.06%Color and Shape:SolidMolecular weight:427.18Glipizide
CAS:<p>Glipizide (CP 28720) is a short-acting, second-generation sulfonylurea with hypoglycemic activity.</p>Formula:C21H27N5O4SPurity:99.67% - 99.75%Color and Shape:SolidMolecular weight:445.54VU0134992 hydrochloride
CAS:<p>VU0134992 hydrochloride is the first subtype-preferring, orally active and selective blocker of Kir4.1 potassium channel pore(IC50 : 0.97 μM).</p>Formula:C20H32BrClN2O2Purity:>99.99%Color and Shape:SolidMolecular weight:447.84NS13001
CAS:<p>NS13001, an oral SK channel modulator, shows promise for SCA2 therapy; EC50: 1.8 µM (SK2), 0.14 µM (SK3).</p>Formula:C17H16ClN7Purity:99.55%Color and Shape:SolidMolecular weight:353.81Terfenadine
CAS:<p>Terfenadine, metabolized to fexofenadine by CYP3A4, is a non-sedative antihistamine targeting H1 receptors.</p>Formula:C32H41NO2Purity:98.76% - 99.75%Color and Shape:SolidMolecular weight:471.67Mefloquine hydrochloride
CAS:<p>Mefloquine hydrochloride (Mefloquin hydrochloride) is a quinoline derivative used for the prevention and therapy of P. falciparum malaria.</p>Formula:C17H17ClF6N2OPurity:99% - 99.74%Color and Shape:Off-White To Yellow SolidMolecular weight:414.77Linopirdine
CAS:<p>Linopirdine (DuP 996) is a TRPV1 agonist.</p>Formula:C26H21N3OPurity:99.45% - 99.78%Color and Shape:SolidMolecular weight:391.46Dronedarone hydrochloride
CAS:<p>Dronedarone hydrochloride (SR33589) is an amiodarone analog which has an effective and promising treatment for Atrial fibrillation.</p>Formula:C31H44N2O5S·HClPurity:99.61%Color and Shape:SolidMolecular weight:593.22Minocycline hydrochloride
CAS:<p>Minocycline HCl: tetracycline antibiotic, treats bacterial infections and acne, may cause acute or chronic hepatitis.</p>Formula:C23H28ClN3O7Purity:99.28% - >99.99%Color and Shape:Bright Yellow-Orange Amorphous Solid Crystalline YellowMolecular weight:493.94Gliclazide
CAS:<p>Gliclazide (SE1702), an oral antihyperglycemic agent, belongs to the sulfonylurea class of insulin secretagogues, which act by stimulating beta-cells of the</p>Formula:C15H21N3O3SPurity:99.58%Color and Shape:SolidMolecular weight:323.41NS19504
CAS:<p>NS19504 is an activator of Ca2+-activated K+ channel with EC50 of 11.0 µM.</p>Formula:C10H9BrN2SPurity:99.87%Color and Shape:SolidMolecular weight:269.16Propafenone
CAS:<p>Propafenone: a drug for ventricular arrhythmias with mild beta-blocker activity, prolongs refractory period, and reduces heart automaticity.</p>Formula:C21H27NO3Purity:99.02%Color and Shape:SolidMolecular weight:341.44Proflavine Hemisulfate
CAS:<p>Proflavine Hemisulfate (3,6-Diaminoacridine hemisulfate) is the hemisulfate salt of proflavine, an acridine-derived fluorescent contrast and disinfectant agent.</p>Formula:C13H12N3O2S0Purity:99.55%Color and Shape:Orange To Red PowderMolecular weight:258.29ML418
CAS:<p>ML418 is a potent, selective and CNS penetrating Kir7.1 potassium channel blocker (IC50 = 310 nM), and also potently inhibits Kir6.2/SUR1.</p>Formula:C19H24ClN3O3Purity:99.3%Color and Shape:SolidMolecular weight:377.87Clofilium tosylate
CAS:<p>Clofilium tosylate is a potassium channel blocker, induces apoptosis on human promyelocytic leukemia (HL-60) cells.</p>Formula:C28H44ClNO3SPurity:99.68%Color and Shape:SolidMolecular weight:510.17Phenformin hydrochloride
CAS:<p>Phenformin hydrochloride (Phenformin HCl) is an agent belonging to the biguanide class of antidiabetics with antihyperglycemic activity.</p>Formula:C10H16ClN5Purity:97.11% - 99.80%Color and Shape:Lactic AcidosisMolecular weight:241.72Eleclazine hydrochloride
CAS:<p>Eleclazine hydrochloride (GS 6615 hydrochloride) is a novel inhibitor of late Na+ current (IC50: 0.7 uM).</p>Formula:C21H17ClF3N3O3Purity:99.86%Color and Shape:SolidMolecular weight:451.83BMS-191095
CAS:<p>BMS-191095 is mitochondrial ATP-sensitive potassium (mitoKATP) channel activator.</p>Formula:C22H21ClN4O2Purity:>99.99%Color and Shape:SolidMolecular weight:408.88Hydroxyhexamide
CAS:<p>Hydroxyhexamide ((±)-Hydroxyhexamid) is a pharmacologically active metabolite of Acetohexamide, used as a hypoglycemic agent.</p>Formula:C15H22N2O4SPurity:98.91%Color and Shape:SolidMolecular weight:326.41Brompheniramine maleate
CAS:<p>Brompheniramine maleate (Dimotane) is an antagonist against histamine H1 receptors.</p>Formula:C16H19BrN2·C4H4O4Purity:99.80%Color and Shape:Crystal PowderMolecular weight:435.31AZD 7009
CAS:<p>AZD 7009 is a novel antiarrhythmic compound that inhibits the sodium current of hNav1.5 in CHO K1 cells with an IC50 of 11 uM.</p>Formula:C23H34N4O5Purity:98.42% - 98.51%Color and Shape:SoildMolecular weight:446.54Tolbutamide
CAS:<p>Tolbutamide (HLS 831) is a sulphonylurea hypoglycemic agent with actions and uses similar to those of CHLORPROPAMIDE.</p>Formula:C12H18N2O3SPurity:99.80% - 99.93%Color and Shape:White Crystalline PowderMolecular weight:270.35Miconazole
CAS:<p>Miconazole (R18134) is an imidazole antifungal agent that is used topically and by intravenous infusion.</p>Formula:C18H14Cl4N2OPurity:98% - >99.99%Color and Shape:SolidMolecular weight:416.13Flufenamic acid
CAS:<p>Flufenamic acid (Arlef) is an anthranilic acid derivative with analgesic, anti-inflammatory, and antipyretic properties.</p>Formula:C14H10F3NO2Purity:98.68%Color and Shape:White To Light Yellow Crystalline PowderMolecular weight:281.23NS5806
CAS:<p>NS5806 activates K+ currents, slows KV4.2/4.3 decay with KChIP2, and boosts KV4.3/KChIP2 peaks (EC50=5.3μM).</p>Formula:C16H8Br2F6N6OPurity:97.95%Color and Shape:SolidMolecular weight:574.07BMS-394136
CAS:<p>BMS-394136 (BMS 394136) is a KV1.5 antagonist for the treatment of cardiovascular diseases such as arrhythmias and atrial fibrillation.</p>Formula:C24H21Cl2FN4OPurity:98.19% - 98.67%Color and Shape:SolidMolecular weight:471.35DCEBIO
CAS:<p>DCEBIO, a 1-EBIO derivative, enhances Cl- secretion via hIK1 K+ channel and apical conductance in T84 cells.</p>Formula:C9H8Cl2N2OPurity:99.89%Color and Shape:SolidMolecular weight:231.08IK1 inhibitor PA-6
CAS:<p>IK1 inhibitor PA-6 (PA-6) is a selective and potent inhibitor of IK1 (KIR2.x ion-channel-carried inward rectifier current)(IC50 of 12-15 nM for human and mouse</p>Formula:C31H32N4O2Purity:98.9%Color and Shape:SolidMolecular weight:492.61Ketanserin
CAS:<p>Ketanserin: quinazoline derivative, 5-HT2 receptor antagonist, may lower blood pressure and inhibit blood clots.</p>Formula:C22H22FN3O3Purity:99.19% - 99.73%Color and Shape:SolidMolecular weight:395.43Tipepidine hydrochloride
CAS:<p>Tipepidine hydrochloride: reversible DA D2 receptor inhibitor, IC50 7.0 μM, with antidepressant effects.</p>Formula:C15H18ClNS2Purity:99.97%Color and Shape:SolidMolecular weight:311.89Tannic acid
CAS:<p>Tannic acid (Gallotannic acid) is a novel hERG channel blocker.</p>Formula:C76H52O46Purity:AR - ARColor and Shape:Light Yellow To Light Brown Solid Solid Particulate/PowderMolecular weight:1701.2Hydrochlorothiazide
CAS:<p>Hydrochlorothiazide (HCTZ) 是一种口服有效的噻嗪类的利尿药，可抑制转化 TGF-β/Smad 信号通路。它通过打开钙激活钾 (KCA) 通道发挥直接的血管松弛作用。它改善心脏功能，减少纤维化并具有降压作用。</p>Formula:C7H8ClN3O4S2Purity:99.43% - 99.50%Color and Shape:Crystals Physical Description Crystals Or White Powder (Ntp 1992)Molecular weight:297.74DCPIB
CAS:<p>DCPIB, a known specific and potent inhibitor of volume-regulated anion channels (VRAC),DCPIB displayed superior selectivity toward TRESK with an IC50 of 0.14 μM</p>Formula:C22H28Cl2O4Purity:99.79% - 99.87%Color and Shape:SolidMolecular weight:427.36VU6036720
<p>VU6036720 is a potent and selective inhibitor of the isomeric Kir4.1/5.1.VU6036720 inhibits Kir4.1/5.1 activity by decreasing the channel open-circuit</p>Formula:C20H22ClFN4O2SPurity:98.1%Color and Shape:SoildMolecular weight:436.93VU591
CAS:<p>VU591 is a selective extra-renal potassium channel inhibitor with an IC₅₀ of 0.24 μM.</p>Formula:C16H12N6O5Purity:99.29% - 99.53%Color and Shape:SolidMolecular weight:368.3Cloperastine hydrochloride
CAS:<p>Cloperastine hydrochloride (HT-11 hydrochloride) is a type of flavonoid.</p>Formula:C20H25Cl2NOPurity:97.74% - 99.42%Color and Shape:SolidMolecular weight:366.33ICA-27243
CAS:<p>ICA-27243: Potent KCNQ2/Q3 opener, oral, EC50 0.38 μM; less effective on KCNQ4, KCNQ3/Q5; antiepileptic.</p>Formula:C12H7ClF2N2OPurity:99.54%Color and Shape:SolidMolecular weight:268.65Repaglinide
CAS:<p>Repaglinide, a benzoic acid derivative, stimulates insulin, treats type 2 diabetes, and may rarely cause acute liver injury.</p>Formula:C27H36N2O4Purity:99.73% - >99.99%Color and Shape:White To Off-White SolidMolecular weight:452.594-Aminopyridine
CAS:<p>4-Aminopyridine (Dalfampridine) is a nonselective potassium (K+) channel blocker that binds to the cytoplasmic side of the cell membrane.</p>Formula:C5H6N2Purity:91.61%Color and Shape:SolidMolecular weight:94.11Glibenclamide
CAS:<p>Glibenclamide (Glyburide) is an antidiabetic sulfonylurea derivative with actions similar to those of chlorpropamide.</p>Formula:C23H28ClN3O5SPurity:99.05% - 99.75%Color and Shape:SolidMolecular weight:494.00Flindokalner
CAS:<p>Flindokalner (BMS-204352) modulates potassium channels, enhances Kv7 subtypes and BKca, inhibits Kv7.1 (Ki=3.7μM), GABAA; has anxiolytic effects in vivo.</p>Formula:C16H10ClF4NO2Purity:99.96%Color and Shape:SolidMolecular weight:359.7Ropivacaine hydrochloride
CAS:<p>Ropivacaine hydrochloride (Ropivacaine monohydrochloride) is the hydrochloride salt of ropivacaine, a local anesthetic of the amide type with analgesic activity</p>Formula:C17H26N2O·HClPurity:99.85% - 99.95%Color and Shape:SolidMolecular weight:310.86Doxapram hydrochloride hydrate
CAS:<p>Doxapram hydrochloride hydrate (Doxapram HCl) inhibits TASK-1, TASK-3, TASK-1/TASK-3 heterodimeric channel function with EC50 of 0.41, 37, 9 μM, respectively.</p>Formula:C24H33ClN2O3C24H30N2O2·ClH·H2OPurity:99.64% - >99.99%Color and Shape:SolidMolecular weight:432.99Diazoxide
CAS:<p>Diazoxide (Proglycem) is a benzothiadiazine derivative that is a peripheral vasodilator used for hypertensive emergencies.</p>Formula:C8H7ClN2O2SPurity:99% - 99.83%Color and Shape:SolidMolecular weight:230.67Amiodarone hydrochloride
CAS:<p>Amiodarone HCl: Antianginal, class III antiarrhythmic. Lengthens heart muscle action, slows heart rate, reduces vascular resistance.</p>Formula:C25H29I2NO3·HClPurity:99.82% - ≥95%Color and Shape:White To Cream Crystalline PowderMolecular weight:681.78Halothane
CAS:<p>Halothane (Anestan) 可以减弱内皮依赖性舒张作用。</p>Formula:C2HBrClF3Purity:98.50% - >99.99%Color and Shape:Colorless Volatile Liquid Density 1 875 G / Cm3 Boiling Point 122 4°F (50 2°C) NoncombustibleMolecular weight:197.38Disopyramide
CAS:<p>Disopyramide, or Triombrin, a class I anti-arrhythmic with membrane-stabilizing effects, has heart depressant, anticholinergic, and anesthetic properties.</p>Formula:C21H29N3OPurity:99.62%Color and Shape:SolidMolecular weight:339.47Quinine
CAS:<p>Quinine is a natural cinchona alkaloid that has been used for centuries in the prevention and therapy of malaria.</p>Formula:C20H24N2O2Purity:99.93% - 99.97%Color and Shape:White Solid PowderMolecular weight:324.42AmmTX3
<p>KV4 channel blocker that inhibits A-type K+ current in mouse neurons; requires DPP6 and DPP10 for effect.</p>Formula:C158H262N50O48S6Purity:98%Color and Shape:SolidMolecular weight:3822.47MASP-2-IN-1
<p>MASP-2-IN-1 (Compound 77) is an inhibitor of mannan-binding lectin-associated serine proteases (MASP), specifically targeting MASP2 and MASP3, with IC50 values of 11.4 nM and 13.2 µM, respectively. It shows weak inhibitory activity on hERG with an IC50 of 175 µM. This compound exhibits poor stability in mouse plasma, with a half-life of 4.4 hours.</p>Formula:C22H21N7O3SColor and Shape:SolidMolecular weight:463.512CHET3
CAS:<p>CHET3 is a highly selective allosteric activator for TASK-3-containing K2P channels. CHET3 has shown potent in vivo analgesic effects. Cost-effective and quality-assured.</p>Formula:C21H21N5O3SPurity:99.64% - >99.99%Color and Shape:SoildMolecular weight:423.49Heteropodatoxin-1
<p>Heteropodatoxin-1 (HpTx1), a spider peptide toxin, acts as an inhibitor of the Kv4.2 current, while concurrently inhibiting Nav1.7 and activating Nav1.9</p>Formula:C168H238N46O51S6Purity:98%Color and Shape:SolidMolecular weight:3910.35Tertiapin LQ
<p>Kir1.1 channel blocker, 250x selective; Kd: Kir1.1 (1.1 nM), Kir3.1/3.2 (274 nM), Kir3.1/3.4 (361 nM). Tertiapin-Q derivative.</p>Formula:C106H179N33O24S4Purity:98%Color and Shape:SolidMolecular weight:2428.03GsAF-II
<p>GsAF-II is a peptide toxin that selectively blocks hERG1 subtype potassium channels through a voltage-dependent mechanism and impedes Nav1.x subtype sodium</p>Formula:C176H261N47O45S7Purity:98%Color and Shape:SolidMolecular weight:3979.7Lei-Dab7
CAS:<p>Selective KCa2.2 channel blocker with Kd 3.8 nM, >200-fold specificity, enhances LTP, convulsive in vivo.</p>Formula:C141H236N46O39S6Purity:98%Color and Shape:SolidMolecular weight:3392.06Guangxitoxin 1E
CAS:<p>Guangxitoxin 1E acts as a gating modifier since it shifts the voltage-dependence of Kv2.1 K+ currents towards depolarized potentials.</p>Formula:C178H248N44O45S7Purity:98%Color and Shape:SolidMolecular weight:3948.61BeKm-1
CAS:<p>Potent, selective hERG (KV11.1) blocker; doesn't affect 14 other K+ channels; extends QTc in rabbit heart dose-dependently.</p>Formula:C174H261N51O52S6Purity:98%Color and Shape:SolidMolecular weight:4091.65Phe-Met-Arg-Phe, amide
CAS:<p>Phe-Met-Arg-Phe amide activates K+ current in neurons (ED50=23 nM), co-localizes with neuropeptide Y in brain regions.</p>Formula:C29H42N8O4SPurity:98%Color and Shape:SolidMolecular weight:598.76Aekatperone
<p>Aekatperone, a reversible KATP channel inhibitor, exhibits an IC50 of 9 μM. It is utilized in research related to congenital hyperinsulinism (CHI).</p>Formula:C20H25N5O2SColor and Shape:SolidMolecular weight:399.51Ion Channel Targeted Library
<p>A unique collection of 931 compounds targeting ion channels for research in ion channels-related diseases and ion channel drug discovery;</p>Color and Shape:Odour SolidADWX 1 TFA
<p>ADWX 1 TFA is a novel peptide that potently targets and inhibits the Kv1.3 channel, with an IC50 of 1.89 pM. It specifically suppresses the activity of the Kv1.3 channel, in addition to inhibiting initial calcium signaling and NF-κB activation. This compound has been shown to ameliorate symptoms in rats with experimental autoimmune encephalomyelitis (EAE). ADWX 1 TFA is utilized in research focused on T-cell-mediated autoimmune diseases.</p>Formula:C169H281N57O46S7·xC2HF3O2Color and Shape:SolidMolecular weight:4071.85 (free base)Apamin acetate
<p>Apamin acetate: Selective Ca2+-activated K+ channel blocker, 18-amino acid bee venom peptide, promotes synapse repair, anti-inflammatory.</p>Purity:96.97%Color and Shape:SolidPinacidil monohydrate
CAS:<p>Pinacidil monohydrate is a potassium channel activator, antihypertensive drug.</p>Formula:C13H21N5OPurity:99.94% - 99.98%Color and Shape:PowderMolecular weight:263.344-Hydroxytolbutamide
CAS:<p>4-Hydroxytolbutamide is a drug metabolite derived from the metabolism of Tolbutamide by CYP2C8 and CYP2C9 a sulfonylurea hypoglycemic agent.</p>Formula:C12H18N2O4SPurity:98%Color and Shape:White To Off-WhiteMolecular weight:286.35Mesoridazine Besylate
CAS:<p>Mesoridazine Besylate (Serentil), a piperidine antipsychotic and phenothiazine, treats schizophrenia; it's a thioridazine metabolite.</p>Formula:C27H32N2O4S3Purity:99.58%Color and Shape:SolidMolecular weight:544.75Dalazatide HCl
<p>Dalazatide HCl is a peptide and specific Kv1.3 inhibitor that suppresses the activation and proliferation of memory effector T cells,</p>Color and Shape:SolidMolecular weight:4317.53 (Free base)Charybdotoxin
CAS:<p>Specific inhibitor of the big conductance Ca2+-activated K+ channel.</p>Formula:C176H277N57O55S7Purity:98%Color and Shape:SolidMolecular weight:4295.95Margatoxin
CAS:<p>KV1.3 channel blocker, IC50 36 pM, no effect on calcium-activated channels, hinders VEGF-induced Ca++ influx & NO in endothelial cells.</p>Formula:C178H286N52O50S7Purity:98%Color and Shape:SolidMolecular weight:4178.96Phe-Met-Arg-Phe amide trifluoroacetate
CAS:<p>Phe-met-arg-phe amide trifluoroacetate is an activator of K+ current with an ED50 of 23nm on the fundus nerve.</p>Formula:C33H44F6N8O8SPurity:98%Color and Shape:SolidMolecular weight:826.81Apamin
CAS:<p>Apamin: 18-amino acid bee venom peptide, blocks SK channels, anti-inflammatory, anti-fibrotic, strongly basic.</p>Formula:C79H131N31O24S4Purity:98%Color and Shape:SolidMolecular weight:2027.34Myomodulin
CAS:<p>Myomodulin is a neuropeptide present in molluscs, insects, and gastropods.Myomodulin is present in two identified aplysia neurons that contain myomodulin A the</p>Formula:C36H67N11O8S2Purity:98%Color and Shape:SolidMolecular weight:846.12Dendrotoxin K
CAS:<p>Dendrotoxin K blocks Kv1.1 channels, modulating glutamate release in CA3 neurons by controlling presynaptic spike timing.</p>Formula:C294H462N84O75S6Color and Shape:SolidMolecular weight:6559.66RU-TRAAK-2
CAS:<p>RU-TRAAK-2 reversibly inhibits TWIK-related K+ channel, inactive on Kv1.2, GIRK2, Slo1.</p>Formula:C19H17N3OSPurity:99.81%Color and Shape:SolidMolecular weight:335.42GsAF-I
<p>GsAF-I is a potent blocker of Na_v and hERG1 channels, exhibiting half-maximal inhibitory concentrations (IC50s) of 0.36 μM (Na_v 1.1), 0.6 μM (Na_v 1.2), 1.28</p>Formula:C160H244N46O42S7Purity:98%Color and Shape:SolidMolecular weight:3708.39HG1 Toxin
<p>HG1 Toxin is a peptide found in the venom of the scorpion Heterometrus fulvipes, known for its ability to inhibit the potassium channel Kv1.3 (potassium channel Kv1.3). Additionally, HG1 Toxin exhibits trypsin inhibitory activity (Ki=107 nM), making it useful for research into autoimmune diseases.</p>Formula:C337H503N103O97S6Molecular weight:7736.59176Potassium Channel Targeted Library
<p>A unique collection of xnum potassium channel blockers and agonists for high throughput and high content screening;</p>Color and Shape:Odour SolidADWX 1
<p>Potent KV1.3 blocker, IC50: 0.0019 nM; less effective on KV1.1. Curbs CD4+ T cell activation; eases rat multiple sclerosis model.</p>Formula:C169H281N57O46S7Purity:98%Color and Shape:SolidMolecular weight:4071.86Cesium chloride
CAS:<p>Cesium chloride (CsCl) is considered to be the most toxic of the alkali chlorides, inhibiting fungal growth.</p>Formula:ClCsPurity:98%Color and Shape:White Solid CrystallineMolecular weight:168.36Agitoxin-2
CAS:<p>Potent Shaker K+ channel blocker (Ki = 0.64 nM). Also inhibits Kv1.3, Kv1.6 and Kv1.1 K+ channels (Ki values are 4, 37 and 44 pM respectively).</p>Formula:C169H278N54O48S8Purity:98%Color and Shape:SolidMolecular weight:4090.87KV1.3-IN-1
<p>KV1.3-IN-1 (Compound trans-18), a selective KV1.3 channel inhibitor with IC50 values of 230 nM in Ltk cells and 26.12 nM in PHA-activated T-lymphocytes,</p>Formula:C23H30N2O4SPurity:98%Color and Shape:SolidMolecular weight:430.56Guanfu base A
CAS:<p>Guanfu base A is a potent noncompetitive CYP2D6 inhibitor (Ki: 1.20 μM in HLMs; Ki: 0.37 μM for rCYP2D6). It also inhibits HERG channel current.</p>Formula:C24H31NO6Purity:99.71% - 99.85%Color and Shape:SolidMolecular weight:429.5Dendrotoxin K TFA
<p>Dendrotoxin K TFA, a Kv1.1 channel blocker, modulates glutamate release in CA3 neurons by time-dependently regulating the presynaptic spike waveform [1].</p>Formula:C294H462N84O75S6·XC2HF3OC2Purity:98%Color and Shape:SolidMolecular weight:6559.66 (free base)BKCa activator-1
<p>BKCa activator-1 (Compound 51b) is an orally active activator of BKCa calcium-activated potassium channels with an EC50 of 2.82 μM. It promotes K+ efflux, leading to cell membrane hyperpolarization and inhibition of smooth muscle contraction. In a spontaneous hypertensive rat (SHR) model, it alleviates urinary incontinence and exhibits antitussive effects in a guinea pig cough model.</p>Formula:C22H23F7N2O3Color and Shape:SolidMolecular weight:496.418Ebio3
<p>Ebio3 is a selective potassium ion channel (KCNQ2) inhibitor with an IC50 of 1.2 nM. It binds to the KCNQ2 channel via its hydrophobic tail, causing the inward movement of the S6 helix, which results in the closure of the internal gate. The inhibitory effect of Ebio3 is equally effective on pathogenic KCNQ2 mutants, such as R75C and I238L, reducing their outward current by approximately 80%. Ebio3 holds potential for research in neurological disorders like epilepsy.</p>Formula:C19H23F2N3O2Color and Shape:SolidMolecular weight:363.4KNa1.1-IN-2
CAS:<p>KNa1.1-IN-2 (Compound Z05) is a selective KNa1.1 channel inhibitor capable of penetrating the blood-brain barrier, and exhibits significant efficacy on hERG channels. It binds to KNa1.1 channels, effectively blocking channel activity caused by Gain-of-function (GOF) mutations, thus intervening in KCNT1-related seizures. Additionally, it inhibits the GOF mutant Y796H, making KNa1.1-IN-2 a promising candidate for research into KCNT1-associated epilepsy disorders.</p>Formula:C24H27NOColor and Shape:SolidMolecular weight:345.48Vesnarinone HCl
<p>Vesnarinone HCl is an oral PDE3 inhibitor improving heart contractility, affecting calcium and potassium flux. Used in heart failure research.</p>Formula:C22H26ClN3O4Purity:99.17%Color and Shape:SoildMolecular weight:431.91Ebio2
<p>Ebio2 is an effective activator of KCNQ2.</p>Formula:C17H19F2N3O2Color and Shape:SolidMolecular weight:335.349Iberiotoxin
CAS:<p>Selective blocker of the big conductance Ca2+-activated K+ channel.</p>Formula:C179H274N50O55S7Purity:98%Color and Shape:SolidMolecular weight:4230Cromakalim
CAS:<p>Cromakalim (BRL 34915) is an ATP-dependent K(+) channel opener, a smooth muscle relaxant with antiepileptic activity.</p>Formula:C16H18N2O3Purity:99.39%Color and Shape:SolidMolecular weight:286.33Nateglinide D5
CAS:<p>Nateglinide D5 is a deuterium labeled Nateglinide.</p>Formula:C19H27NO3Purity:98%Color and Shape:SolidMolecular weight:322.45QO-58
CAS:<p>QO-58 is a novel Kv7 activator (opener) that activates neuronal Kv7/KCNQ/M channels, danti-nociceptive effects on inflammatory pain</p>Formula:C18H8Cl2F4N4OPurity:99.17%Color and Shape:SolidMolecular weight:443.18Flecainide
CAS:<p>Flecainide is an orally administered antiarrhythmic agent acting as a sodium channel blocker and IKr inhibitor,PSVT.</p>Formula:C17H20F6N2O3Purity:99.896%Color and Shape:SolidMolecular weight:414.34Neosolaniol
CAS:<p>Neosolaniol, a type A trichothecene mycotoxin produced by Fusarium species, strongly induces an anorectic (loss of appetite) response.</p>Formula:C19H26O8Purity:98%Color and Shape:SolidMolecular weight:382.4KCNQ1 activator-1
CAS:<p>N-[4-(4-Methoxyphenyl)-2-thiazolyl]-2-piperidinecarboxamide is a potent KCNQ1 activator for LQTS research.</p>Formula:C22H23N3O4S2Purity:99.71%Color and Shape:SolidMolecular weight:457.57Endoxifen Z-isomer hydrochloride
CAS:<p>Endoxifen Z-isomer hydrochloride (Endoxifen HCl) is the active metabolite of Tamoxifen, which is an effective and selective estrogen receptor antagonist.</p>Formula:C25H28ClNO2Color and Shape:SolidMolecular weight:409.95Clamikalant sodium
CAS:<p>Clamikalant sodium (HMR 1098) is an ATP-dependent potassium channel (KATP) cardiac-selective blocker, used in the study of arrhythmias.</p>Formula:C19H21ClN3NaO5S2Purity:99.95%Color and Shape:SolidMolecular weight:493.96Oxypeucedanin
CAS:<p>1.</p>Formula:C16H14O5Purity:98.66% - 98.85%Color and Shape:SolidMolecular weight:286.28Ibutilide Fumarate
CAS:<p>Ibutilide Fumarate is a class III antiarrhythmic, prolonging action potentials by enhancing sodium influx, and can extend QT interval.</p>Formula:(C20H36N2O3S)2·C4H4O4Purity:99.68% - 99.74%Color and Shape:SolidMolecular weight:885.23Guanosine 5'-diphosphate disodium salt
CAS:<p>5'-GDP-Na2: a nucleoside diphosphate, iron mobilizer, blocks hepcidin-ferroportin, affects IL-6/stat-3.</p>Formula:C10H13N5Na2O11P2Purity:99.40%Color and Shape:White PowderMolecular weight:487.16XE 991 dihydrochloride
CAS:<p>XE 991 dihydrochloride is a Kv7 (KCNQ) channel blocker.</p>Formula:C26H22Cl2N2OPurity:98.68%Color and Shape:SolidMolecular weight:449.37SKA-31
CAS:<p>SKA-31 (Naphtho[1,2-d]thiazol-2-ylamine) is an activator of KCa3.1 and KCa2 channels (EC50s: 260, 2900, 2900 nM for KCa3.1, KCa2.1 and KCa2.2 respectively).</p>Formula:C11H8N2SPurity:99.38%Color and Shape:SolidMolecular weight:200.26Ropivacaine hydrochloride monohydrate
CAS:<p>Ropivacaine hydrochloride monohydrate (LEA-103 HCl) is an anaesthetic agent and blocks impulse conduction through inhibiting sodium ion influx reversibly.</p>Formula:C17H29ClN2O2Purity:99.94% - 99.95%Color and Shape:White SolidMolecular weight:328.88Cholesterol myristate
CAS:<p>Cholesterol myristate, a natural steroid in Chinese medicine, affects GABAA, nicotinic receptors, and potassium channels.</p>Formula:C41H72O2Purity:99.65%Color and Shape:SolidMolecular weight:597.01Quinidine sulfate dihydrate
CAS:<p>Quinidine sulfate dihydrate (Pitayine Sodium) is a potent and selective cytochrome P450db inhibitor</p>Formula:C40H54N4O10SPurity:99.85%Color and Shape:White To Light Yellow Crystal PowdeMolecular weight:782.9ML277
CAS:<p>ML277 (CID-53347902) was identified as a potent activator of KCNQ1 channels (EC(50)=260 nM).</p>Formula:C23H25N3O4S2Purity:99.35%Color and Shape:SolidMolecular weight:471.59APD668
CAS:<p>APD668 is a potent GPR119 agonist with EC50 of 2.7 nM and 33 nM for hGPR119 and ratGPR119, respectively.</p>Formula:C21H24FN5O5SPurity:99.74% - 99.97%Color and Shape:SolidMolecular weight:477.51Amifampridine
CAS:<p>Amifampridine blocks nerve potassium channels, extends action potentials, boosts acetylcholine release, and treats rare muscle diseases.</p>Formula:C5H7N3Purity:99.82%Color and Shape:Slightly Beige PowderMolecular weight:109.13TKIM
CAS:<p>TKIM is a TWIK-related potassium channel 1 (TREK-1) inhibitor, binding to the pocket of the intermediate (IM) state of TREK-1.</p>Formula:C18H14ClN3O2SPurity:99.47%Color and Shape:SolidMolecular weight:371.84ICA-069673
CAS:<p>ICA-069673 is an activator of KCNQ2/Q3 potassium channel (IC50: 0.69 μM).</p>Formula:C11H6ClF2N3OPurity:99.04% - 99.68%Color and Shape:SolidMolecular weight:269.63NS309
CAS:<p>NS309 activates SK/KCa2, IK/KCa3.1 (0.12-1.2 μM EC50, 10-90 nM EC50), and Kv11.1 channels; doesn't affect BK/KCa1.1; modulates neuronal firing.</p>Formula:C8H4Cl2N2O2Purity:97.55%Color and Shape:SolidMolecular weight:231.04BAPTA-AM
CAS:<p>BAPTA-AM is a calcium chelator that is cell-permeable and selective, blocking hERG, hKv1.3, and hKv1.5 channels (IC50=1.3/1.45/1.23 μM).</p>Formula:C34H40N2O18Purity:98% - 99.47%Color and Shape:White Powder Or Crystalline PowderMolecular weight:764.68Quinidine
CAS:<p>Quinidine is a stereoisomer of the antimalarial agent quinine and a class Ia antiarrhythmic agent. for the treatment of abnormal heart rhythms and also malaria.</p>Formula:C20H24N2O2Purity:97.03% - 99.99%Color and Shape:Crystals With 2 5 Mol Water Of Crystallization; Crystals From Dilute Alcohol Physical Description Crystals Or White Powder (Ntp 1992)Molecular weight:324.42Talatisamine
CAS:<p>Talatisamine and TEA mitigate Aβ oligomer effects on I(K), bolstering cell survival and reducing K(+) loss-induced apoptosis; promising for further study.</p>Formula:C24H39NO5Purity:98.62% - 99.44%Color and Shape:SolidMolecular weight:421.57VU0134992
CAS:<p>VU0134992 is an Kir4.1 blocker with an IC50 value of 0.97 μM</p>Formula:C20H31BrN2O2Purity:99.86%Color and Shape:SolidMolecular weight:411.38Endoxifen (Z-isomer)
CAS:<p>Endoxifen Z-isomer (EDX) is a key active metabolite of tamoxifen with higher affinity and specificity to estrogen receptors that inhibits aromatase activity.</p>Formula:C25H27NO2Purity:99.19% - 99.81%Color and Shape:SolidMolecular weight:373.49Paederosidic acid methyl ester
CAS:<p>Paederosidic acid methyl ester has antinociception, is possibly related to the pathway of NO-cGMP-ATP sensitive K(+) channels.</p>Formula:C19H26O12SPurity:99.67% - 99.91%Color and Shape:SolidMolecular weight:478.4720(S)-Ginsenoside Rg3
CAS:<p>20(S)-Ginsenoside Rg3 (Rg3) possess an ability to inhibit the lung metastasis of tumor cells via inhibition of the adhesion and invasion of tumor cells.</p>Formula:C42H72O13Purity:98.11% - 99.93%Color and Shape:SolidMolecular weight:785.01KCNQ2/3 activator-1
CAS:<p>KCNQ2/3 activator-1 is a Kv7.2/Kv7.3 (KCNQ2/3) potassium channel activator.</p>Formula:C23H29FN2OPurity:99.16% - 99.47%Color and Shape:SolidMolecular weight:368.492,2,2-Trichloroethanol
CAS:<p>2,2,2-Trichloroethanol is an agonist of the nonclassical K2P channels TREK-1 and TRAAK.</p>Formula:C2H3Cl3OPurity:99.74%Color and Shape:LiquidMolecular weight:149.4Yoda 1
CAS:<p>Yoda 1 is an agonist of the Piezo1 channel that agonizes human- and mouse-derived Piezo1. Yoda 1 is also an inhibitor of GlyT2. Cost-effective, quality assurance.</p>Formula:C13H8Cl2N4S2Purity:98% - 99.98%Color and Shape:SolidMolecular weight:355.27Quinine hydrochloride dihydrate
CAS:<p>Quinine hydrochloride dihydrate (Quinine HCl Dihydrate) is a white crystalline K+ channel blocker, used to treat malaria.</p>Formula:C20H24N2O2·HCl·2H2OPurity:99.91%Color and Shape:White To Light Yellow Crystal PowderMolecular weight:396.91Kv2-IN-A1
CAS:<p>Kv2-IN-A1 is an inhibitor of Kv2.1 and Kv2.2.</p>Formula:C20H17ClN4OSPurity:98.83%Color and Shape:SolidMolecular weight:396.89Almitrine mesylate
CAS:<p>Almitrine mesylate targets Ca2+-dependent K+ channels in rat cells, used for chronic lung hypoxemia.</p>Formula:C28H37F2N7O6S2Purity:99.96%Color and Shape:CoaMolecular weight:669.76Azimilide Dihydrochloride
CAS:<p>Azimilide Dihydrochloride (NE-10064 Dihydrochloride), a novel class III antiarrhythmic agent, blocks both the IKs and IKr with antiarrhythmic activity.</p>Formula:C23H30Cl3N5O3Purity:97.59% - ≥95%Color and Shape:SolidMolecular weight:530.88ML365
CAS:<p>ML365 is a novel selective small molecule inhibitor of TASK1(KCNK3).</p>Formula:C22H20N2O3Purity:98.78%Color and Shape:SolidMolecular weight:360.41VU0071063
CAS:<p>VU0071063 is a Kir6.2/SUR1 activator.</p>Formula:C18H22N4O2Purity:99.33%Color and Shape:SolidMolecular weight:326.39Quinine dihydrochloride
CAS:<p>Quinine dihydrochloride (Quinine bimuriate) is a primary alkaloid of various species of Cinchona (Rubiaceae).</p>Formula:C20H26Cl2N2O2Purity:99.79% - 99.97%Color and Shape:White SolidMolecular weight:397.34Sematilide hydrochloride
CAS:<p>Sematilide hydrochloride (CK-1752) is a class III antiarrhythmic. It is a selectively delayed rectifier K+ current (IKr) channel blocker.</p>Formula:C14H24ClN3O3SPurity:99.14%Color and Shape:SolidMolecular weight:349.87Dofetilide
CAS:<p>Dofetilide (UK 68789), a class III antiarrhythmic sulfonamide, blocks Ikr cardiac channels, prolongs action potential, and treats atrial fibrillation/flutter.</p>Formula:C19H27N3O5S2Purity:97.85% - 99.06%Color and Shape:Off-White Or Yellowish Crystalline PowderMolecular weight:441.56AUT1
CAS:<p>AUT1 (AUT-1) is a novel specific modulator of Kv3 channels (EC50: 4.7 and 4.9 uM for Kv3.1b and Kv3.2a).</p>Formula:C18H19N3O4Purity:99.8% - 99.95%Color and Shape:SolidMolecular weight:341.36Iptakalim Hydrochloride
CAS:<p>Iptakalim, a lipophilic para-amino compound, is a novel ATP-sensitive potassium channel (KATP) opener, as well as an α4β2-containing nicotinic acetylcholine</p>Formula:C9H22ClNPurity:98%Color and Shape:SolidMolecular weight:179.731GSK369796 Dihydrochloride
CAS:<p>GSK369796 Dihydrochloride (N-tert-butylisoquine),is an anti-malaria drug candidate.</p>Formula:C20H24Cl3N3OPurity:>99.99%Color and Shape:SolidMolecular weight:428.78PAP-1
CAS:<p>PAP-1 (5-(4-Phenoxybutoxy)psoralen) is a selective, and orally active Kv1.3 blocker (EC50: 2 nM).</p>Formula:C21H18O5Purity:99.35% - 99.75%Color and Shape:White SolidMolecular weight:350.36Nigericin sodium salt
CAS:<p>Nigericin sodium salt, an antibiotic and NLRP3 activator from S. hygroscopicus, inhibits Golgi and gram-positive bacteria, blocking viral activation.</p>Formula:C40H67NaO11Purity:98.2% - 99.52%Color and Shape:SolidMolecular weight:746.94Atpenin A5
CAS:<p>Atpenin A5 is a potent and highly specific complex II inhibitor (IC50 ~10 nM).</p>Formula:C15H21Cl2NO5Purity:97.33% - 99.91%Color and Shape:SolidMolecular weight:366.24LY 303511 hydrochloride
CAS:<p>LY 303511 hydrochloride is a potent mTOR inhibitor</p>Formula:C19H19ClN2O2Purity:98.47%Color and Shape:SolidMolecular weight:342.82Mitiglinide Calcium
CAS:<p>Mitiglinide Calcium (KAD-1229) is a blood glucose-lowering drugs, stimulating insulin secretion by closing the ATP-sensitive K+ channels in pancreatic beta-</p>Formula:(C19H24NO3)2·CaPurity:99.83%Color and Shape:White Crystal PosderMolecular weight:668.88Flupirtine maleate
CAS:<p>Flupirtine maleate (Katadolon maleate), a centrally acting non-opioid analgesia, is the salt form of Flupirtine. Flupirtine is an NMDA receptor antagonist.</p>Formula:C15H17FN4O2·C4H4O4Purity:99.5% - 99.9%Color and Shape:Off-White Crystalline PowderMolecular weight:420.39Senicapoc
CAS:<p>Senicapoc (ICA-17043) blocks Gardos channel, reduces RBC dehydration, IC50: 11 nM for rubidium flux, 30 nM for dehydration. Used in Sickle Cell therapy.</p>Formula:C20H15F2NOPurity:95.7% - 99.47%Color and Shape:SolidMolecular weight:323.34E-4031 dihydrochloride
CAS:<p>E-4031 is a methanesulfonanilide class III antiarrhythmic agent that prolongs cardiac action potential duration by blocking ERG K+ channels (IC50 = 29 nM)</p>Formula:C21H29Cl2N3O3SPurity:99.31% - 99.87%Color and Shape:SolidMolecular weight:474.44Allocryptopine
CAS:<p>Allocryptopine (Thalictrimine) induces muscle contraction and relaxation in urinary bladder and ileum, respectively.</p>Formula:C21H23NO5Purity:99.41% - ≥95%Color and Shape:SolidMolecular weight:369.41KS176
CAS:<p>KS176: selective BCRP inhibitor, potent against breast cancer drug resistance; ineffective on P-gp, MRP1.</p>Formula:C22H19N3O5Purity:99.61% - 99.61%Color and Shape:SolidMolecular weight:405.45-Hydroxydecanoate sodium
CAS:<p>5-Hydroxydecanoate sodium: KATP channel blocker, IC50 ~30μM; mitochondrial substrate; antioxidant.</p>Formula:C10H19NaO3Purity:99.24% - 99.89%Color and Shape:SolidMolecular weight:210.25VU0810464
CAS:<p>VU0810464 is a non-ureaG protein-gated inwardly-rectifying potassium channels (GIRK, Kir3) activator.</p>Formula:C18H21ClFN3OPurity:99.62%Color and Shape:SolidMolecular weight:349.83Loureirin B
CAS:<p>Loureirin B suppresses fibrosis by modulating MMPs/TIMPs, hindering fibroblast growth, and targeting TGF-β1/Smad2/3 pathway.</p>Formula:C18H20O5Purity:99.33% - 99.86%Color and Shape:SolidMolecular weight:316.35Mitiglinide calcium hydrate
CAS:<p>Mitiglinide calcium hydrate (S-21403 calcium hydrate) is a drug for the treatment of type 2 diabetes.</p>Formula:C38H52CaN2O8Purity:98.97% - 99.96%Color and Shape:White SolidMolecular weight:704.91A2793
CAS:<p>A2793 is a dual inhibitor of TWIK-associated acid-sensitive K+ channel 1 (TASK-1)/TRESK, with an IC50 for mTRESK of 6.8 μM.</p>Formula:C13H12ClNO3Purity:98.54%Color and Shape:SolidMolecular weight:265.69O-Nornuciferine
CAS:<p>O-Nornuciferine reveals distinct in vitro hERG blockages measured in HEK293 cells with the IC50 value of 2.89 uM.</p>Formula:C18H19NO2Purity:99.86%Color and Shape:SolidMolecular weight:281.35ML213
CAS:<p>ML213 (CID-3111211) is a selective activator of Kv7.2 (KCNQ2) and Kv7.4 (KCNQ4) channels, enhances Kv7.2 and Kv7.4 channels with EC50s of 230 and 510 nM,</p>Formula:C17H23NOPurity:>99.99%Color and Shape:SolidMolecular weight:257.37Levcromakalim
CAS:<p>Levcromakalim (BRL 38227) is an activator of the ATP-sensitive K+ channel.</p>Formula:C16H18N2O3Purity:99.74%Color and Shape:SolidMolecular weight:286.33NS 11021
CAS:<p>NS 11021 (NS11021) , a novel opener of large-conductance Ca(2+)-activated K(+) channels</p>Formula:C16H9BrF6N6SPurity:97.26%Color and Shape:SolidMolecular weight:511.24Tetraethylammonium bromide
CAS:<p>Tetraethylammonium bromide (TEA bromide) can selectively block potassium channels.</p>Formula:C8H20BrNPurity:98%Color and Shape:White SolidMolecular weight:210.16ML133 hydrochloride
CAS:<p>ML133 hydrochloride (ML133 HCl) is a selective potassium channel inhibitor for Kir2.1, has no effect on Kir1.1 and weak activity for Kir4.1 and Kir7.1.</p>Formula:C19H19NO·HClPurity:99.48%Color and Shape:SolidMolecular weight:313.82SKF-96365 hydrochloride
CAS:<p>SKF-96365 hydrochloride (SKF96365) , a SOCE inhibitor, exhibits potent anti-neoplastic activity by inducing cell-cycle arrest and apoptosis in colorectal Y</p>Formula:C22H27ClN2O3Purity:99.47% - 99.92%Color and Shape:SolidMolecular weight:402.91Rimtuzalcap
CAS:<p>Rimtuzalcap (CAD-1883), a selective modulator for SK channels, may treat movement disorders like SCA and ET.</p>Formula:C18H24F2N6OPurity:99.64%Color and Shape:SolidMolecular weight:378.42A2764 dihydrochloride
CAS:<p>A2764 dihydrochloride is a highly selective inhibitor of TRESK.</p>Formula:C15H21Cl3N2OPurity:99.05%Color and Shape:SolidMolecular weight:351.7(±)-Naringenin
CAS:<p>(±)-Naringenin (Naringenine) is a natural product.</p>Formula:C15H12O5Purity:98.06%Color and Shape:SolidMolecular weight:272.25Dihydroberberine
CAS:<p>Dihydroberberine has anti-atherosclerotic, anti-inflammatory, hypolipidemic and antitumor activities.</p>Formula:C20H19NO4Purity:93.77%Color and Shape:SolidMolecular weight:337.37Nateglinide
CAS:<p>Nateglinide is an oral drug for type 2 diabetes, stimulating insulin release; may cause rare acute liver injury.</p>Formula:C19H27NO3Purity:99.93% - 99.94%Color and Shape:White Crystalline PowderMolecular weight:317.42Guanosine 5'-diphosphate
CAS:<p>Guanosine 5'-diphosphate (GDP) as Potential Iron Mobilizer, Preventing the Hepcidin-Ferroportin Interaction and Modulating the Interleukin-6/Stat-3 Pathway.</p>Formula:C10H15N5O11P2Purity:98.46% - 99.52%Color and Shape:SolidMolecular weight:443.2ML 297
CAS:<p>ML 297 is a selective Kir3.1/3.2 (GIRK1/2) channel activator (IC50 values are 160, 887 and 914 nM for GIRK1/2, GIRK1/4 and GIRK1/3 respectively).</p>Formula:C17H14F2N4OPurity:97.85%Color and Shape:SolidMolecular weight:328.32NS1643
CAS:<p>NS1643 is a potent human ether-a-go-go related gene (hERG) KV11.1 channel activator with EC50 of 10.5 μM.</p>Formula:C15H10F6N2O3Purity:98.37% - 99.31%Color and Shape:SolidMolecular weight:380.24GAL-021
CAS:<p>GAL-021 an intravenous BKCa-channel blocker.</p>Formula:C11H22N6OPurity:97.71% - 99.66%Color and Shape:SolidMolecular weight:254.33Daurisoline
CAS:<p>Daurisoline ((R,R)-Daurisoline) is a hERG inhibitor. Daurisoline is also an autophagy blocker.</p>Formula:C37H42N2O6Purity:98% - 99.96%Color and Shape:Light Yellow PowderMolecular weight:610.74NS-1619
CAS:<p>NS1619 have cardio-protective effects after ischemia-reperfusion injury.</p>Formula:C15H8F6N2O2Purity:97.66% - 98%Color and Shape:SolidMolecular weight:362.23GW9508
CAS:<p>GW9508(GW 9508) is a potent and selective agonist for FFA1 (GPR40), stimulates insulin secretion in a glucose-sensitive manner.</p>Formula:C22H21NO3Purity:97.89% - 99.19%Color and Shape:SolidMolecular weight:347.41JNJ 303
CAS:<p>JNJ 303 is a potent blocker of IKs (IC50 : 64 nM).</p>Formula:C21H29ClN2O4SPurity:99.28%Color and Shape:SolidMolecular weight:440.98TRAM-34
CAS:<p>TRAM-34 (Triarylmethane-34), an effective and specific inhibitor of the intermediate-conductance Ca2+-activated K+ channel, does not block cytochrome P450.</p>Formula:C22H17ClN2Purity:99.01% - 99.91%Color and Shape:SolidMolecular weight:344.84ML335
CAS:<p>ML335 is a selective activator of TREK-1 and TREK-2.</p>Formula:C15H14Cl2N2O3SPurity:99.73% - 99.79%Color and Shape:SolidMolecular weight:373.25ICA 110381
CAS:<p>ICA 110381 is a KCNQ2/Q3 potassium channel opener for the treatment of epilepsy</p>Formula:C12H8Cl2N2OPurity:97.72%Color and Shape:SolidMolecular weight:267.11Flecainide hydrochloride
CAS:<p>Flecainide is a medication used to prevent and treat abnormally fast heart rates. This includes ventricular and supraventricular tachycardias.</p>Formula:C17H21ClF6N2O3Purity:97.79%Color and Shape:SolidMolecular weight:450.81Minoxidil sulfate
CAS:<p>Minoxidil sulfate (U-58838) is the active metabolite required to exert the vasodilatory and hair growing effects of minoxidil.</p>Formula:C9H15N5O4SPurity:99.01% - 99.72%Color and Shape:White Crystalline SolidMolecular weight:289.31ASP2905
CAS:<p>ASP-2905 is a potent and selective inhibitor of potassium channel Kv12.2 encoded by the Kcnh3/BEC1 gene.</p>Formula:C20H17FN8Purity:97.29%Color and Shape:SolidMolecular weight:388.4AM-92016 hydrochloride
CAS:<p>AM-92016 is a specific blocker of rectifier potassium current.</p>Formula:C19H24Cl2N2O4S·HClPurity:98.68%Color and Shape:SolidMolecular weight:483.84NS6180
CAS:<p>NS6180 is a potent and selective KCa3.1 channel inhibitor(IC50= 9 nM). It prevents T-cell activation and inflammation.</p>Formula:C16H12F3NOSPurity:99.83% - ≥95%Color and Shape:SolidMolecular weight:323.33Tetraethylammonium chloride
CAS:<p>Tetraethylammonium chloride is a quaternary ammonium compound.</p>Formula:C8H20ClNPurity:≥95%Color and Shape:White Solid Solid Particulate/PowderMolecular weight:165.7RY785
CAS:<p>RY785 is a potent and selective inhibitor of voltage-gated potassium channel such as KV2.2 (IC50 = 50 nM). RY785 may be used in pain relief studies.</p>Formula:C21H20N4O2SPurity:99.78%Color and Shape:SolidMolecular weight:392.47Enflurane
CAS:<p>Enflurane (Efrane), a volatile anaesthetic, inhibits Ca2+-activated K+ channels and is used to gauge anesthesia levels in gas chromatography.</p>Formula:C3H2ClF5OPurity:99.64%Color and Shape:Clear Colorless Liquid Ordinary Temperature And Pressure Bp 56 8°C Density 1 50 G Cm-3 At Room Temperature Used As AnMolecular weight:184.49SCH-23390 hydrochloride
CAS:<p>SCH-23390 hydrochloride (R-(+)-SCH23390 hydrochloride) is an effective dopamine receptor antagonist, and for the D1(Ki=0.2 nM) and D5(Ki=0.3 nM).</p>Formula:C17H19Cl2NOPurity:98% - 99.83%Color and Shape:SolidMolecular weight:324.24ICA-105574
CAS:<p>ICA-105574 activates hERG, enhancing peak current and shortening action potential, while modulating activation kinetics.</p>Formula:C19H14N2O4Purity:98.89%Color and Shape:SolidMolecular weight:334.33Branaplam
CAS:<p>Branaplam (LMI 070) is a highly potent, selective and orally active small molecule SMN2 splicing modulator.</p>Formula:C22H27N5O2Purity:98.28% - 99.72%Color and Shape:SolidMolecular weight:393.48
