Autophagy
Autophagy inhibitors target the cellular process of autophagy, which involves the degradation and recycling of cellular components through lysosomes. Autophagy is a critical mechanism for maintaining cellular homeostasis, but its dysregulation is implicated in various diseases, including cancer, neurodegeneration, and infections. Inhibitors of autophagy can block this process, making them valuable tools for studying the role of autophagy in disease and developing therapeutic strategies. At CymitQuimica, we offer autophagy inhibitors to support your research in cell biology, oncology, and neurodegenerative diseases.
Found 1424 products of "Autophagy"
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sbp-7455
CAS:<p>SBP-7455 potently inhibited ULK1/2 enzymatic activity in vitro and in cells, reduced the viability of TNBC cells and had oral bioavailability in mice.</p>Formula:C16H17F3N4O2Purity:97.90% - 99.842%Color and Shape:SolidMolecular weight:354.33Kaempferol
CAS:<p>Kaempferol (Robigenin) is a natural flavonoid and an inverse agonist of ERRα and ERRγ.</p>Formula:C15H10O6Purity:98% - 99.41%Color and Shape:Yellow Needles From Alcohol And Water SolidMolecular weight:286.24Amsacrine hydrochloride
CAS:<p>Amsacrine hydrochloride (acridinyl anisidide hydrochloride) is topoisomerase II inhibitor , is used in the treatment of acute myelogenous leukemia.</p>Formula:C21H20ClN3O3SPurity:99.05% - 99.92%Color and Shape:SolidMolecular weight:429.92Typhaneoside
CAS:<p>Typhaneoside (Aervitrin) is a flavonoid glycoside plant extract with potential ability to treat primary dysmenorrhea through the Shaofu Zhuyu decoction.</p>Formula:C34H42O20Purity:98.92% - 99.95%Color and Shape:SolidMolecular weight:770.69DPN
CAS:<p>DPN (Diarylpropionitrile) is an selective agonist of estrogen receptor β (ERβ) .</p>Formula:C15H13NO2Purity:99.01%Color and Shape:Off-White SolidMolecular weight:239.27Pantoprazole
CAS:<p>Pantoprazole (BY1023) is a proton pump inhibitor used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal reflux</p>Formula:C16H15F2N3O4SPurity:99.28% - 99.63%Color and Shape:Almost White SolidMolecular weight:383.37AS-605240
CAS:<p>AS-605240 is an effective and specific inhibitor of PI3Kγ (IC50/Ki: 87.8 nM).</p>Formula:C12H7N3O2SPurity:97% - 99.91%Color and Shape:SolidMolecular weight:257.27Nutlin-3a
CAS:<p>Nutlin-3a is the active enantiomer of Nutlin-3, an MDM2 antagonist that inhibits MDM2-p53 interaction. Nutlin-3a has antitumor activity. Cost-effective and quality-assured.</p>Formula:C30H30Cl2N4O4Purity:95.62% - 99.71%Color and Shape:SolidMolecular weight:581.49FIPI
CAS:<p>FIPI, a halopemide derivative, strongly blocks PLD1 and PLD2 (IC50s: 25 nM, 20 nM) and hinders PLD-mediated cell activity.</p>Formula:C23H24FN5O2Purity:97.21% - 98.68%Color and Shape:SolidMolecular weight:421.47Sirtinol
CAS:<p>Sirtinol is a selective SIRT1/2 inhibitor (IC50: 131/38 μM).</p>Formula:C26H22N2O2Purity:97.12% - 99.96%Color and Shape:SolidMolecular weight:394.47Quercitrin
CAS:<p>Quercitrin (3-rhamnosyl quercetin) is a plant-derived flavonoid compound, displays antioxidant and anti-inflammatory activities.</p>Formula:C21H20O11Purity:98.89% - 99.66%Color and Shape:Yellow Crystals From Dil Methanol Or Ethanol SolidMolecular weight:448.38Embelin
CAS:<p>Embelin (Embelic acid), isolated from the Japanese Ardisia herb, is an inhibitor of the X-linked inhibitor of apoptosis (IC50: 4.1 uM).</p>Formula:C17H26O4Purity:97.07% - 99.88%Color and Shape:SolidMolecular weight:294.39GNE-9605
CAS:<p>GNE-9605 is a highly effective, specifical, and brain-penetrant LRRK2 inhibitor (IC50: 19 nM).</p>Formula:C17H20ClF4N7OPurity:98.55% - 98.75%Color and Shape:SolidMolecular weight:449.83PX-478
CAS:<p>PX-478 is a HIF-1α inhibitor with selectivity, oral activity, and blood-brain barrier permeability.</p>Formula:C13H20Cl4N2O3Purity:97% - 99.79%Color and Shape:SolidMolecular weight:394.12Rotenone
CAS:<p>Rotenone, a plant-derived insecticide, inhibits mitochondrial electron transport, found in Leguminosae.</p>Formula:C23H22O6Purity:89.58% - 99.88%Color and Shape:Less To Brownish Crystals Or A White To Brownish-White Crystalline Powder Has Neither Odor Nor Taste (Ntp 1992)Molecular weight:394.42Quisinostat dihydrochloride
CAS:<p>Quisinostat dihydrochloride (JNJ26854165(Quisinostat) 2HCl) 是一种有口服活性，高效的 pan-HDAC 抑制剂，具有广泛的抗肿瘤活性。它对 HDAC1、HDAC2、HDAC4、HDAC10和HDAC11 的IC50值分别为 0.11 nM、0.33 nM、0.64 nM、0.46 nM 和 0.37 nM。</p>Formula:C21H28Cl2N6O2Purity:97.13%Color and Shape:SolidMolecular weight:467.39Mdivi-1
CAS:<p>Mdivi-1 (Mitochondrial division inhibitor 1) is a mitochondrial division inhibitor that inhibits DRP1 and Dynamin I (IC50=1-10 μM).</p>Formula:C15H10Cl2N2O2SPurity:96.57% - 99.23%Color and Shape:SolidMolecular weight:353.22SMER28
CAS:<p>SMER28 triggers autophagy in cells without mTOR, blocking amyloid beta buildup.</p>Formula:C11H10BrN3Purity:99.94% - >99.99%Color and Shape:SolidMolecular weight:264.12Rasagiline Mesylate
CAS:<p>Rasagiline Mesylate (AGN1135) is a novel MAO-B inhibitor, which can treat idiopathic Parkinson's disease.</p>Formula:C13H17NO3SPurity:99.33%Color and Shape:White PowderMolecular weight:267.34LC3-mHTT-IN-AN1
CAS:<p>LC3-mHTT-IN-AN1 is a mHTT-LC3 linker compound that interacts with both mutant huntingtin protein (mHTT) and LC3B.</p>Formula:C15H9Br2NO3Purity:97.26%Color and Shape:SolidMolecular weight:411.04Alisertib
CAS:<p>Alisertib (MLN 8237) is a specific Aurora A inhibitor (IC50: 1.2 nM). The selectivity of Alisertib(MLN 8237) is >200-fold higher for Aurora A than Aurora B.</p>Formula:C27H20ClFN4O4Purity:98.31% - >99.99%Color and Shape:SolidMolecular weight:518.92Afatinib
CAS:<p>Afatinib (BIBW 2992) is an irreversible and orally EGFR family inhibitor that inhibits EGFR and HER2. Afatinib has antitumor activity. Cost effective and quality assured.</p>Formula:C24H25ClFN5O3Purity:98.56% - 99.9%Color and Shape:Off-White SolidMolecular weight:485.94Tubastatin A
CAS:<p>Tubastatin A: Selective HDAC6 inhibitor, IC50 of 15 nM, 1000x less effective on other isozymes except HDAC8.</p>Formula:C20H21N3O2Purity:97.22% - 99.51%Color and Shape:SolidMolecular weight:335.4Mycro 3
CAS:<p>Mycro 3 is potent and selective for c-Myc in whole cell assays.</p>Formula:C24H17ClF2N6O4Purity:99.51% - 99.61%Color and Shape:SolidMolecular weight:526.88Neferine
CAS:<p>Neferine: anti-tumor, enhances DOX efficacy, prevents diabetic vasculopathy; mediates via CYP3A4, GSH depletion, blocks ROS/Akt/NF-κB.</p>Formula:C38H44N2O6Purity:98.81% - 99.65%Color and Shape:SolidMolecular weight:624.773-Bromopyruvic acid
CAS:<p>3-Bromopyruvic acid (Hexokinase II Inhibitor II, 3-BP) is a hexokinase II inhibitor with Ki of 2.4 mM for glycolysis/hexokinase inhibition.</p>Formula:C3H3BrO3Purity:95% - 99.644%Color and Shape:White To Pale Yellow Crystalline PowderMolecular weight:166.96MK-2206 dihydrochloride
CAS:<p>MK-2206 dihydrochloride (MK-2206 2HCl) is a variant Akt inhibitor that inhibits Akt1, Akt2, and Akt3 (IC50=8/12/65 nM) with orally active, highly potent and</p>Formula:C25H23Cl2N5OPurity:99.228% - 99.94%Color and Shape:SolidMolecular weight:480.39Diosgenin glucoside
CAS:<p>Diosgenin glucoside (Trillin) and other synthetic glycosides with similar activities may be of use in the management of hypercholesterolemia and atherosclerosis</p>Formula:C33H52O8Purity:97.17% - 99.44%Color and Shape:SolidMolecular weight:576.76Fangchinoline
CAS:<p>Fangchinoline (Tetrandrine B) is extracted from Stephania tetrandra S. Moore.</p>Formula:C37H40N2O6Purity:99.86% - >99.99%Color and Shape:SolidMolecular weight:608.72Schisandrol B
CAS:<p>Schisandrol B fights neuroinflammation, liver/renal damage, and reduces cell growth via multiple signaling pathways.</p>Formula:C23H28O7Purity:99.14% - 99.95%Color and Shape:SolidMolecular weight:416.46AZD 6482
CAS:<p>AZD 6482 (KIN-193) is a potent and selective inhibitor of p110β and PI3Kβ with IC50 values of 0.69nM and 10nM.Cost-effective and quality-assured.</p>Formula:C22H24N4O4Purity:99.79% - 99.95%Color and Shape:SolidMolecular weight:408.45Brefeldin A
CAS:<p>Brefeldin A (Cyanein) belongs to the class of macrolide antibiotics and is an ATPase inhibitor (IC50=0.2 μM).</p>Formula:C16H24O4Purity:96.45% - 99.89%Color and Shape:White SolidMolecular weight:280.36Dioscin
CAS:<p>Dioscin (Collettiside III) is a saponin with antitumor activities.</p>Formula:C45H72O16Purity:99.85% - 99.87%Color and Shape:SolidMolecular weight:869.04GLPG1837
CAS:<p>GLPG1837 (ABBV-974) is an effective CFTR potentiator, with EC50s of 3 nM and 339 nM for F508del and G551D CFTR, respectively.</p>Formula:C16H20N4O3SPurity:99.64% - 99.91%Color and Shape:SolidMolecular weight:348.42ABT-737
CAS:<p>ABT-737 is a BH3 mimetic and an inhibitor of Bcl-2, Bcl-xL, and Bcl-w. ABT-737 exhibits antitumor activity and anti-aging activity. Cost-effective and quality-assured.</p>Formula:C42H45ClN6O5S2Purity:98.15% - >99.99%Color and Shape:SolidMolecular weight:813.43Neflamapimod
CAS:<p>Neflamapimod (VX-745) , a specific and effective inhibitor of p38α(IC50=10 nM), is 22-fold greater specificity against p38β and no inhibition activity to p38γ.</p>Formula:C19H9Cl2F2N3OSPurity:97.88% - 99.75%Color and Shape:SolidMolecular weight:436.26Turofexorate Isopropyl
CAS:<p>Turofexorate Isopropyl (XL335) is a potent, selective, and orally bioavailable FXR agonist with EC50 of 4 nM</p>Formula:C25H24F2N2O3Purity:98.55% - 99.73%Color and Shape:SolidMolecular weight:438.47Calcimycin
CAS:<p>Calcimycin (A-23187) is a polyether antibiotic that transports Ca²⁺, uncouples phosphorylation, and inhibits ATPase in mitochondria.</p>Formula:C29H37N3O6Purity:98%Color and Shape:SolidMolecular weight:523.62Vandetanib
CAS:<p>Vandetanib (ZD6474) is a potent inhibitor of VEGFR2 (IC50: 40 nM). It also inhibits VEGFR3 and EGFR.</p>Formula:C22H24BrFN4O2Purity:99.7% - >99.99%Color and Shape:White SolidMolecular weight:475.35SGI-1776
CAS:<p>SGI-1776 (Pim-Kinase Inhibitor IX) has been used in trials studying the treatment of Prostate Cancer, Non-Hodgkins Lymphoma, and Relapsed/Refractory Leukemias.</p>Formula:C20H22F3N5OPurity:99.3% - >99.99%Color and Shape:SolidMolecular weight:405.42Carbamazepine
CAS:<p>Carbamazepine: a tricyclic with anticonvulsant and analgesic effects, treats trigeminal neuralgia.</p>Formula:C15H12N2OPurity:99.78% - 99.79%Color and Shape:SolidMolecular weight:236.27Milciclib
CAS:<p>Milciclib (PHA-848125) is a potent CDK2 inhibitor with a 45 nM IC50, selective over CDK1/2/4/5/7. In Phase 2 trials.</p>Formula:C25H32N8OPurity:99.28%Color and Shape:SolidMolecular weight:460.57STF-62247
CAS:<p>STF-62247 is TGN inhibitor with IC50 of 0.625 μM and 16 μM in RCC4 and RCC4/VHL cells, respectively.</p>Formula:C15H13N3SPurity:99.6% - 99.67%Color and Shape:SolidMolecular weight:267.35Fenretinide
CAS:<p>Fenretinide (4-HPR) is an orally-active synthetic retinoid derivative with potential antineoplastic and chemopreventive activities.</p>Formula:C26H33NO2Purity:98% - 99.68%Color and Shape:Yellow PowderMolecular weight:391.55Isoalantolactone
CAS:<p>Isoalantolactone (Isohelenin), isolated from Inula spp., can inhibit the growth of several types of Y cells.</p>Formula:C15H20O2Purity:99.75% - 99.94%Color and Shape:SolidMolecular weight:232.32CD437
CAS:<p>CD437 (AHPN) is a specifc Retinoic Acid Receptor γ (RARγ) agonist.</p>Formula:C27H26O3Purity:98.92% - 99.63%Color and Shape:SolidMolecular weight:398.49Zoledronic acid monohydrate
CAS:<p>Zoledronic acid monohydrate (CGP 42446) is a synthetic imidazole bisphosphonate analog with anti-bone-resorption activity.</p>Formula:C5H12N2O8P2Purity:99.91%Color and Shape:White To Off-White PowderMolecular weight:290.1Betulinic acid
CAS:<p>Betulinic acid, a lupane-type triterpene from white birch bark, has antiretroviral, antimalarial, anti-inflammatory, and anticancer properties.</p>Formula:C30H48O3Purity:99.12% - 99.7%Color and Shape:White Crystalline PowderMolecular weight:456.7ISOGINKGETIN
CAS:<p>ISOGINKGETIN (4',4'''-Dimethylamentoflavone), a compound derived from the leaves of Ginkgo biloba, to up-regulate adiponectin secretion.</p>Formula:C32H22O10Purity:98% - 99.72%Color and Shape:SolidMolecular weight:566.51FERULIC ACID METHYL ESTER
CAS:<p>FERULIC ACID METHYL ESTER (Methyl ferulate) is a hydroxycinnamic acid that is abundant in plants. FERULIC ACID METHYL ESTER has antioxidant activities.</p>Formula:C11H12O4Purity:99.66% - 99.95%Color and Shape:SolidMolecular weight:208.21Wogonoside
CAS:<p>Wogonoside (Wogonin 7-O-glucuronide) acts as a positive allosteric modulator of the benzodiazepine site of the GABAA receptor.</p>Formula:C22H20O11Purity:98.24% - >99.99%Color and Shape:SolidMolecular weight:460.39Oroxin B
CAS:<p>Oroxin B (Hypocretin-2) has antioxidant activity.</p>Formula:C27H30O15Purity:98.22% - 99.81%Color and Shape:SolidMolecular weight:594.52Topotecan
CAS:<p>Topotecan (NSC-609669) is a Topoisomerase I inhibitor,and is an antineoplastic agent used to treat ovarian cancer that works by inhibiting DNA topoisomerases.</p>Formula:C23H23N3O5Purity:96.14% - 98.23%Color and Shape:Light Yellow Needle Crystal Or Crystalline PowderMolecular weight:421.45Obatoclax Mesylate
CAS:<p>Obatoclax Mesylate (GX15-070) is a Bcl-2 antagonist (Ki: 0.22 μM) and can induce apoptosis with up-regulation of Bim, induced cytochrome c release, and</p>Formula:C20H19N3O·CH4O3SPurity:99.58% - 99.88%Color and Shape:SolidMolecular weight:413.49LRRK2-IN-1
CAS:<p>LRRK2-IN-1 is an effective and selective LRRK2 inhibitor.</p>Formula:C31H38N8O3Purity:98% - 98.82%Color and Shape:SolidMolecular weight:570.69Cabazitaxel
<p>Cabazitaxel (XRP6258) is a taxane used for castration-resistant metastatic prostate cancer post-docetaxel failure.</p>Formula:C45H57NO14Purity:98% - 99.93%Color and Shape:SolidMolecular weight:835.93Daphnetin
CAS:<p>Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM),</p>Formula:C9H6O4Purity:97.47% - 99.8%Color and Shape:SolidMolecular weight:178.14H-89 dihydrochloride
CAS:<p>H-89 dihydrochloride (5-Isoquinolinesulfonamide) is a potent inhibitor of protein kinase A (PKA; IC50: 0.14 μM, Ki: 48 nM).</p>Formula:C20H20BrN3O2S·2HClPurity:98.22% - >99.99%Color and Shape:SolidMolecular weight:519.28PD98059
CAS:<p>PD98059 is an MEK inhibitor that inhibits MEK1 and MEK2 (IC50=2/50 μM) and is non-ATP-competitive.</p>Formula:C16H13NO3Purity:98.63% - >99.99%Color and Shape:Yellow SolidMolecular weight:267.28ML327
CAS:<p>ML327 is a MYC blocker. ML327 can also de-repress E-cadherin transcription and reverse Epithelial-to-Mesenchymal Transition (EMT).</p>Formula:C19H18N4O4Purity:98.47%Color and Shape:SolidMolecular weight:366.37Chloroquine
CAS:<p>Chloroquine: antimalarial, anti-inflammatory, autophagy/TLRs inhibitor, treats arthritis, effective against COVID-19 in vitro. EC50: 1.13 μM.</p>Formula:C18H26ClN3Purity:99.5% - 99.98%Color and Shape:White To Slightly Yellow Crystalline Powder SolidMolecular weight:319.87Samotolisib
CAS:<p>Samotolisib (LY3023414) inhibits PI3K, DNA-PK, mTOR; tested for solid tumors including breast and colon cancer.</p>Formula:C23H26N4O3Purity:98.41% - 99.69%Color and Shape:SolidMolecular weight:406.48Sitagliptin phosphate
CAS:<p>Sitagliptin phosphate (MK-0431 phosphate) is a dipeptidyl peptidase-4 (DPP4) inhibitor.</p>Formula:C16H18F6N5O5PPurity:99.72% - 99.91%Color and Shape:White SolidMolecular weight:505.31A-484954
CAS:<p>A-484954 (A 484954) is a highly specific eukaryotic elongation factor-2 (eEF2, IC50: 280 nM) inhibitor.</p>Formula:C13H15N5O3Purity:97.47% - 99.86%Color and Shape:SolidMolecular weight:289.29KN-92 phosphate
CAS:<p>KN-92 phosphate (KN92-H3PO4) is an inactive derivative of KN-93.</p>Formula:C24H28ClN2O7PSPurity:99.86%Color and Shape:SolidMolecular weight:554.98Autophinib
CAS:<p>Autophinib is a potent autophagy inhibitor with a novel chemotype with IC50 values of 90 and 40 nM for autophagy in starvation induced autophagy assay and</p>Formula:C14H11ClN6O3Purity:99.25% - 99.41%Color and Shape:SolidMolecular weight:346.73Salvigenin
CAS:<p>Salvigenin is a potent hMAO-A inhibitor, has neuroprotective, antitumor and immunomodulatory effects.</p>Formula:C18H16O6Purity:99.17% - 99.78%Color and Shape:SolidMolecular weight:328.32Wortmannin
CAS:<p>Wortmannin (SL-2052) is a PI3K inhibitor (IC50=3 nM) that is covalent and irreversible.</p>Formula:C23H24O8Purity:95.84% - 99.76%Color and Shape:White SolidMolecular weight:428.43Leonurine
CAS:<p>Leonurine (SCM-198) is an alkaloid that has been found in H. leonuri and with anti-oxidative and anti-inflammatory.</p>Formula:C14H21N3O5Purity:98.55%Color and Shape:White Crystalline PowderMolecular weight:311.33GW786034B
CAS:<p>Pazopanib HCl (Votrient) inhibits VEGFR1-3, PDGFR, FGFR, c-Kit, c-Fms with IC50 range 10-146 nM in cell-free assays.</p>Formula:C21H23N7O2S·HClPurity:99.87%Color and Shape:SolidMolecular weight:473.98PF-04691502
CAS:<p>PF-04691502 is a potent and selective inhibitor of PI3K and mTOR kinases with antitumor activity.</p>Formula:C22H27N5O4Purity:96.27% - ≥95%Color and Shape:SolidMolecular weight:425.48Losmapimod
CAS:<p>Losmapimod (GSK-AHAB) (GW856553X; SB856553; GSK-AHAB) is a specific, potent, and orally active p38 MAPK inhibitor (pKi: 8.1/7.6 for p38α/β).</p>Formula:C22H26FN3O2Purity:98.35% - 99.89%Color and Shape:SolidMolecular weight:383.46DC661
CAS:<p>DC661 is a palmitoyl-protein thioesterase 1 (PPT1) inhibitor that acts as an anti-lysosomal agent by inhibiting autophagy, demonstrating anti-cancer activity.</p>Formula:C31H39Cl2N5Purity:99.07%Color and Shape:SolidMolecular weight:552.58Linifanib
CAS:<p>Linifanib (AL-39324) (ABT-869) is a novel, potent ATP-competitive VEGFR/PDGFR inhibitor for KDR (IC50: 4 nM), CSF-1R (IC50: 3 nM), Flt-1/3 (IC50: 3/4 nM) and</p>Formula:C21H18FN5OPurity:98% - 98.24%Color and Shape:SolidMolecular weight:375.4Indophagolin
CAS:<p>Indophagolin: autophagy inhibitor, IC50 140 nM; blocks P2X4, P2X1, P2X3 receptors, IC50s 2.71, 2.40, 3.49 μM.</p>Formula:C19H15BrClF3N2O3SPurity:99.76%Color and Shape:SolidMolecular weight:523.75Saracatinib
CAS:<p>Saracatinib (AZD0530) (AZD0530) is an effective Src inhibitor (IC50: 2.7 nM), and effective to Lck, Fyn, Lyn, Blk, Fgr and c-Yes.</p>Formula:C27H32ClN5O5Purity:98% - 99.63%Color and Shape:SolidMolecular weight:542.03Pamapimod
CAS:<p>Pamapimod (R1503) (R-1503, Ro4402257) is a novel, selective inhibitor of p38 mitogen-activated protein kinase.</p>Formula:C19H20F2N4O4Purity:99.52% - 99.99%Color and Shape:SolidMolecular weight:406.38Crizotinib hydrochloride
CAS:<p>Crizotinib hydrochloride (PF-02341066 hydrochloride) is a novel inhibitor of anaplastic lymphoma kinase and c-Met(IC50s of 20 and 8 nM)</p>Formula:C21H23Cl3FN5OPurity:98.73% - 98.87%Color and Shape:SolidMolecular weight:486.8Danusertib
CAS:<p>Danusertib (PHA-739358) is a small-molecule 3-aminopyrazole derivative with potential antineoplastic activity.</p>Formula:C26H30N6O3Purity:97.88% - 98.79%Color and Shape:White PowderMolecular weight:474.553-Methyladenine
CAS:<p>3-Methyladenine (3-MA) is a PI3K inhibitor that selectively inhibits class IB PI3Kγ (IC50=60 μM) and class III VPS34 (IC50=25 μM).</p>Formula:C6H7N5Purity:98.02% - 99.65%Color and Shape:SolidMolecular weight:149.15WYC-209
CAS:<p>WYC-209 inhibits proliferation of malignant murine melanoma tumor-repopulating cells (TRCs, IC50: 0.19 uM). It targets the retinoic acid receptor (RAR).</p>Formula:C20H20N2O3SPurity:99.77%Color and Shape:SolidMolecular weight:368.45Salirasib
CAS:<p>Salirasib: Competitive PPMTase inhibitor, blocks Ras methylation, potential cancer treatment, Ki=2.6 μM.</p>Formula:C22H30O2SPurity:99.45%Color and Shape:SolidMolecular weight:358.54Afatinib Dimaleate
CAS:<p>Afatinib Dimaleate (BIBW 2992MA2) is an orally bioavailable anilino-quinazoline derivative and inhibitor of the EGFR family, with antineoplastic activity.</p>Formula:C32H33ClFN5O11Purity:98.11% - 99.87%Color and Shape:SolidMolecular weight:718.08PFK-015
CAS:<p>PFK-015 (PFK15) is an effective inhibitor of PFKFB3 (IC50: 110 nM) and inhibits PFKFB3 activity in Y cells (IC50: 20 nM).</p>Formula:C17H12N2OPurity:99.7% - 99.85%Color and Shape:SolidMolecular weight:260.29TA-02
CAS:<p>TA-02 is a p38 MAPK inhibitor with IC50 of 20 nM.TA-02 especially inhibits TGFBR-2.</p>Formula:C20H13F2N3Purity:99.35% - 99.79%Color and Shape:SolidMolecular weight:333.33Sepantronium bromide
CAS:<p>Sepantronium bromide (YM155) is a small-molecule proapoptotic agent with potential antineoplastic activity.</p>Formula:C20H19BrN4O3Purity:99.68% - 99.85%Color and Shape:SolidMolecular weight:443.26LY294002
CAS:<p>LY294002 (SF 1101) is a broad-spectrum inhibitor of PI3K, inhibiting PI3Kα, PI3Kδ, and PI3Kβ (IC50=0.5/0.57/0.97 μM).</p>Formula:C19H17NO3Purity:98% - 99.96%Color and Shape:Pale Yellow SolidMolecular weight:307.34Pogostone
CAS:<p>Pogostone: anti-bacterial/fungal, blocks T-cells, modulates cytokines, protects against gastric ulcers, boosts antioxidants/PGE2/NP-SH.</p>Formula:C12H16O4Purity:98.46% - 99.03%Color and Shape:SolidMolecular weight:224.25PFI-1
CAS:<p>PFI-1 (PF-6405761), a specific BET (bromodomain-containing protein) inhibitor for BRD4, is with the IC50 of 0.22 μM in a cell-free assay.</p>Formula:C16H17N3O4SPurity:98.74% - 99.19%Color and Shape:SolidMolecular weight:347.393'-Hydroxypterostilbene
CAS:<p>3'-Hydroxypterostilbene suppresses colon cancer cell growth (COLO 205, HCT-116, HT-29) by triggering apoptosis and autophagy, affecting key pathways.</p>Formula:C16H16O4Purity:98.25% - 99.19%Color and Shape:SolidMolecular weight:272.3BIIB021
CAS:<p>BIIB021 (CNF2024) is an orally-available, fully synthetic inhibitor of HSP90(Ki=1.7 nM, EC50=38 nM).</p>Formula:C14H15ClN6OPurity:98% - 99.82%Color and Shape:SolidMolecular weight:318.76Andrographolide
CAS:<p>Andrographolide (Andrographis)(Andrographis), an irreversible antagonist of NF-κB, has anti-inflammatory and anti-platelet aggregation activities and potential</p>Formula:C20H30O5Purity:99.39% - 99.97%Color and Shape:PowderMolecular weight:350.45Sapanisertib
CAS:<p>Sapanisertib (INK 128) is an oral raptor-mTOR and rictor-mTOR inhibitor with potential cancer-fighting properties.</p>Formula:C15H15N7OPurity:99.19% - >99.99%Color and Shape:SolidMolecular weight:309.33BIX-01294 trihydrochloride
CAS:<p>BIX-01294 trihydrochloride is an inhibitor of G9a histone methyltransferase.In a cell-free assay, the IC50=2.7 μM for G9a histone methyltransferase.</p>Formula:C28H38N6O2·3HClPurity:99.41% - 99.95%Color and Shape:SolidMolecular weight:600.02yangonin
CAS:<p>Yangonin (Y100550) is a novel CB1 receptor ligand with affinity for human recombinant CB1 receptors.</p>Formula:C15H14O4Purity:98.82% - 99.55%Color and Shape:Pale Yellow PowderMolecular weight:258.27Torkinib
CAS:<p>Torkinib (PP 242) (PP 242) is a selective and ATP-competitive mTOR inhibitor (IC50: 8 nM). It also inhibits mTORC1/2 (IC50s: 30/58 nM).</p>Formula:C16H16N6OPurity:99.11%Color and Shape:SolidMolecular weight:308.34CCT007093
CAS:<p>CCT007093 is an effective PPM1D (WIP1) inhibitor (IC50: 8.4 μM).</p>Formula:C15H12OS2Purity:98% - 99.88%Color and Shape:SolidMolecular weight:272.39Resatorvid
CAS:<p>Resatorvid (TAK-242) inhibits TLR4, with IC50s for IL-6, TNF-R, NO at 1.3, 1.9, 1.8 nM respectively.</p>Formula:C15H17ClFNO4SPurity:99.31% - >99.99%Color and Shape:SolidMolecular weight:361.82Fulvestrant
CAS:<p>Fulvestrant (ZM 182780) is an estrogen receptor (ER) antagonist (IC50=9.4 nM) and an agonist of GPR30.</p>Formula:C32H47F5O3SPurity:99.1% - >99.99%Color and Shape:White PowderMolecular weight:606.77Flavopiridol hydrochloride
CAS:<p>Flavopiridol hydrochloride (MDL 107826A), an inhibitor of cyclin-dependent kinase, is a synthetic N-methylpiperidinyl chlorophenyl flavone compound.</p>Formula:C21H21Cl2NO5Purity:98.87% - 99.88%Color and Shape:SolidMolecular weight:438.3Orthanilamide
CAS:<p>Orthanilamide (Orthanilamide) is a molecule containing the sulfonamide functional group attached to an aniline.</p>Formula:C6H8N2O2SPurity:99.72% - 99.96%Color and Shape:White To Pale Cream Crystalline Powder Or CrystalsMolecular weight:172.2AGN 193109
CAS:<p>AGN 193109, a retinoid analog, is a potent and specific antagonist of RARs (Kds: 2 nM, 2 nM, and 3 nM for RARα, RARβ, and RARγ).</p>Formula:C28H24O2Purity:99.87% - 99.89%Color and Shape:SolidMolecular weight:392.49MPP+ iodide
CAS:<p>MPP+ iodide, a neurotoxin byproduct, mimics Parkinson's by killing substantia nigra neurons and affecting neuron transporters, inducing cell death.</p>Formula:C12H12INPurity:99.49% - 99.96%Color and Shape:SolidMolecular weight:297.13Telaglenastat
CAS:<p>Telaglenastat (CB 839) (IC50 of 24 nM), an effective, specific, and oral inhibitor, which is bioavailable glutaminase, for recombinant human GAC.</p>Formula:C26H24F3N7O3SPurity:97.57% - 99.89%Color and Shape:SolidMolecular weight:571.57GSK2578215A
CAS:<p>GSK2578215A is a potent and selective LRRK2 kinase inhibitor.</p>Formula:C24H18FN3O2Purity:99.57% - 99.94%Color and Shape:SolidMolecular weight:399.42Imatinib
CAS:<p>Imatinib (STI571) is a multi-targeted receptor tyrosine kinase inhibitor that selectively inhibits the kinase activities of BCR/ABL, v-Abl, PDGFR, and c-kit</p>Formula:C29H31N7OPurity:99.42% - 99.94%Color and Shape:Off White PowderMolecular weight:493.6Sinomenine
CAS:<p>Sinomenine (Kukoline) is a pure alkaloid isolated from the Sinomenium acutum, is utilized in the treatment of rheumatism and arthritis.</p>Formula:C19H23NO4Purity:99.02% - 99.73%Color and Shape:White PowderMolecular weight:329.39Demethoxycurcumin
CAS:<p>Demethoxycurcumin: antioxidant, anti-inflammatory, anti-proliferative, anti-acanthamoebic, enhances chemo for resistant cancers, inhibits cancer pathways.</p>Formula:C20H18O5Purity:94.54% - 99.86%Color and Shape:SolidMolecular weight:338.35Ginkgolide K
CAS:<p>Ginkgolide K induces protective autophagy through the AMPK/mTOR/ULK1 signalling pathway. It possesses neuroprotective activity.</p>Formula:C20H22O9Purity:99.44% - 99.72%Color and Shape:SolidMolecular weight:406.38Aloperine
CAS:<p>Aloperine exhibits anti-inflammatory, antibacterial, antiviral, and anti-tumor properties.</p>Formula:C15H24N2Purity:98% - 99.88%Color and Shape:Yellow Crystalline PowderMolecular weight:232.36Arglabin
CAS:<p>Arglabin ((+)-Arglabin) is a natural product isolated from Artemisia glabella, is a NLRP3 inflammasome inhibitor, has anti-atherogenic and anticancer effects.</p>Formula:C15H18O3Purity:98.97% - 99.62%Color and Shape:SolidMolecular weight:246.3Bilobalide
CAS:<p>Bilobalide ((-)-Bilobalide), a bioactive from Gingko Biloba, is active on hypoxia-induced alterations.</p>Formula:C15H18O8Purity:98.81% - 99.92%Color and Shape:White SolidMolecular weight:326.3Clematichinenoside AR
CAS:<p>Clematichinenoside AR is anti-inflammatory, immunosuppressive, and combats arthritis via PI3K/Akt and TNF-α pathways.</p>Formula:C82H134O43Purity:99.04% - 99.69%Color and Shape:SolidMolecular weight:1807.92Apocynin
CAS:<p>Apocynin (NSC 2146) is a specific NADPH-oxidase inhibitor (IC50: 10 μM).</p>Formula:C9H10O3Purity:99.71% - 99.98%Color and Shape:Yellowish To Brown PowderMolecular weight:166.17HA15
CAS:<p>HA15 targets BiP/GRP78/HSPA5, showing anti-cancer effects on all tested melanoma cells, resistant or patient-derived.</p>Formula:C23H22N4O3S2Purity:99.77% - 99.86%Color and Shape:SolidMolecular weight:466.58Dimethyl fumarate
CAS:<p>Dimethyl fumarate (DMF) is an orally Nrf2 activator. Dimethyl fumarate has antimicrobial and anti-inflammatory activities. Cost-effective and quality-assured.</p>Formula:C6H8O4Purity:90.51% - >99.99%Color and Shape:White To Off-White Powder White Crystalline PowderMolecular weight:144.13ISRIB (trans-isomer)
CAS:<p>ISRIB (trans-isomer) is a potent inhibitor of PERK that rescues protein translation and prevents SG formation in the presence of P-eIF2α. Cost effective and quality assured.</p>Formula:C22H24Cl2N2O4Purity:97.86% - 99.27%Color and Shape:SolidMolecular weight:451.34Salubrinal
CAS:<p>Salubrinal, a phosphatases (PP1) inhibitor(IC50=1.7 μM), exhibits function on the eukaryotic translation initiation factor 2 subunit (eIF2α).</p>Formula:C21H17Cl3N4OSPurity:97.25% - >99.99%Color and Shape:SolidMolecular weight:479.81Binimetinib
CAS:<p>Binimetinib (ARRY-162) is a MEK1/2 inhibitor (IC50=12 nM) with selective and oral activity. Binimetinib has antitumor activity. Cost-effective and quality-assured.</p>Formula:C17H15BrF2N4O3Purity:98.03% - >99.99%Color and Shape:SolidMolecular weight:441.23Reparixin
CAS:<p>Reparixin inhibits CXCR1 (IC50=1 nM) strongly, CXCR2 weakly (IC50=100 nM), and it's a CXCL8 receptor blocker.</p>Formula:C14H21NO3SPurity:98% - 99.89%Color and Shape:SolidMolecular weight:283.39Daurisoline
CAS:<p>Daurisoline ((R,R)-Daurisoline) is a hERG inhibitor. Daurisoline is also an autophagy blocker.</p>Formula:C37H42N2O6Purity:98% - 99.96%Color and Shape:Light Yellow PowderMolecular weight:610.74Bigelovin
CAS:<p>Bigelovin: RXRα agonist, inhibits mTOR via ROS, induces apoptosis/autophagy, anti-tumor sesquiterpene from Inula sp.</p>Formula:C17H20O5Purity:99.61% - 99.72%Color and Shape:SolidMolecular weight:304.34Britannin
CAS:<p>Britannin, a sesquiterpene lactone, inhibits proliferation and induces apoptosis through the mitochondrial signaling pathway in human breast cancer cells.</p>Formula:C19H26O7Purity:98% - 99.98%Color and Shape:SolidMolecular weight:366.41Verteporfin
CAS:<p>Verteporfin (BPD-MA) is a YAP inhibitor that inhibits YAP-TEAD interactions.</p>Formula:C41H42N4O8Purity:95.37% - 99.82%Color and Shape:Dark Green To Black SolidMolecular weight:718.79Ralimetinib dimesylate
CAS:<p>Ralimetinib dimesylate (LY2228820 dimesylate) is a orally available, p38 MAPK inhibitor with potential anti-inflammatory and antineoplastic activities.</p>Formula:C24H29FN6·2CH4O3SPurity:98% - 99.38%Color and Shape:SolidMolecular weight:612.74Hydroxyprogesterone caproate
CAS:<p>Hydroxyprogesterone caproate (Delalutin) is a synthetic progestin that activates progesterone receptors and inhibits ovulation.</p>Formula:C27H40O4Purity:99.70%Color and Shape:White Or Almost White Crystalline PowerMolecular weight:428.60Tizoxanide
CAS:<p>Tizoxanide (Desacetyl-nitazoxanide) is a metabolite of lamivudine.</p>Formula:C10H7N3O4SPurity:98.89% - 99.28%Color and Shape:SolidMolecular weight:265.25Bardoxolone Methyl
CAS:<p>Bardoxolone Methyl (TP-155) is a synthetic triterpenoid that acts as an activator of the Nrf2 pathway and an inhibitor of the NF-κB pathway with potential anti-</p>Formula:C32H43NO4Purity:97.81% - 99.09%Color and Shape:SolidMolecular weight:505.69BMS-582949 hydrochloride
CAS:<p>The BMS-582949 hydrochloride (BMS-582949 HCl) is a highly specific p38α MAPK inhibitor (IC50: 13 nM).</p>Formula:C22H27ClN6O2Purity:97.57% - 98.75%Color and Shape:SolidMolecular weight:442.95Tazarotene
CAS:<p>Tazarotene (Zorac), a synthetic topical retinoid, treats psoriasis by normalizing keratinocytes and reducing growth.</p>Formula:C21H21NO2SPurity:97.01% - 99.14%Color and Shape:White SolidMolecular weight:351.46Deguelin
CAS:<p>Deguelin ((-)-Deguelin) is a PI3K/AKT Inhibitor, which is a natural product isolated from plants in the Mundulea sericea family.</p>Formula:C23H22O6Purity:96.39% - 99.29%Color and Shape:SolidMolecular weight:394.42BIA 10-2474
CAS:<p>BIA 10-2474 is a long-acting reversible inhibitor of FAAH that increases levels of the neurotransmitter anandamide in the nervous system.</p>Formula:C16H20N4O2Purity:99.27%Color and Shape:SolidMolecular weight:300.36Pirarubicin
CAS:<p>Pirarubicin (Theprubicin), an anthracycline antibiotic, inhibits DNA/RNA synthesis and is used as an antineoplastic.</p>Formula:C32H37NO12Purity:97.80% - 99.15%Color and Shape:Red Crystalline PowderMolecular weight:627.64kaempferide
CAS:<p>kaempferide (4'-Methylkaempferol) is an O-methylated flavonol present in Kaempferia kaempferi with antiviral activity.</p>Formula:C16H12O6Purity:98.31% - 99.66%Color and Shape:SolidMolecular weight:300.26SR12813
CAS:<p>SR12813 (GW 485801) is a pregnane X receptor (PXR) agonist.</p>Formula:C24H42O7P2Purity:99.43%Color and Shape:SolidMolecular weight:504.53Meloxicam
CAS:<p>Meloxicam (Metacam) is a Nonsteroidal Anti-inflammatory Drug.</p>Formula:C14H13N3O4S2Purity:97.09% - 99.60%Color and Shape:Light Yellow SolidMolecular weight:351.40740 Y-P
CAS:<p>740 Y-P (740YPDGFR) is a PI3K activator with cell permeability,binds GST fusion proteins containing the N-and C-terminal SH2 domains of p85. Low-Cost!</p>Formula:C141H222N43O39PS3Purity:98.3% - 99.87%Color and Shape:SolidMolecular weight:3270.7Fluvastatin
CAS:<p>Fluvastatin (XU-62320) is an HMG-CoA reductase inhibitor used to lower plasma cholesterol levels and prevent cardiovascular disease.</p>Formula:C24H26FNO4Purity:98.94%Color and Shape:SolidMolecular weight:411.47ML 145
CAS:<p>ML 145 is a selective antagonist of GPR35/CXCR8 (IC50/EC50 of 20.1 nM)</p>Formula:C24H22N2O5S2Purity:97.74%Color and Shape:SolidMolecular weight:482.57SB 203580 hydrochloride
CAS:<p>SB 203580 hydrochloride (Adezmapimod hydrochloride) is a p38 MAPK inhibitor that induces mitochondrial autophagy and cytosolic autophagy.</p>Formula:C21H17ClFN3OSPurity:97.79%Color and Shape:SolidMolecular weight:413.9mTOR inhibitor-8
CAS:<p>mTOR inhibitor-8 is an mTOR inhibitor and autophagy inducer with antiviral and antitumor activity for the study of non-small cell lung cancer.</p>Formula:C24H19ClN4OSPurity:98.11%Color and Shape:SolidMolecular weight:446.95Ketanserin tartrate
CAS:<p>Ketanserin tartrate (KJK-945 tartrate) is a 5-HT2A receptor and α1-adrenergic receptor antagonist for the study of systemic sclerosis.</p>Formula:C26H28FN3O9Purity:99.68%Color and Shape:SolidMolecular weight:545.51Ezetimibe ketone
CAS:<p>Ezetimibe ketone (EZM-K) exhibits antioxidant activity and alleviates H2O2-induced NRK-52E cell apoptosis by upregulating Nrf2 and HO-1 levels.</p>Formula:C24H19F2NO3Purity:99.32%Color and Shape:White Crystalline SolidMolecular weight:407.41Doxorubicin
CAS:<p>Doxorubicin (Adriamycin) is a Topoisomerase II (Top2) inhibitor with antineoplastic activity.</p>Formula:C27H29NO11Purity:99.31%Color and Shape:Red Crystalline Solid SolidMolecular weight:543.52Chenodeoxycholic Acid sodium salt
CAS:<p>Chenodeoxycholic Acid sodium salt (CDCA sodium salt) is a bile acid in humans that activates the nuclear receptor FXR, rescues axonal degeneration of induced pluripotent stem cell-derived neurons in patients with spastic paraplegia type 5 and cerebral xanthomatosis, and can be used to study pancreatic necrosis.</p>Formula:C24H39NaO4Purity:99.68% - 99.72%Color and Shape:SolidMolecular weight:414.55H-89
CAS:<p>H-89 is a PKA inhibitor, a candidate cardioprotectant, induces spatial learning impairment in rats, and can be used to study myocardial infarction.</p>Formula:C20H20BrN3O2SPurity:98.06%Color and Shape:Off-White PowderMolecular weight:446.36Sitagliptin phosphate monohydrate
CAS:<p>Sitagliptin phosphate monohydrate (MK-0431 phosphate monohydrate) is a potent inhibitor of DPP-IV with IC50 of 19 nM in Caco-2 cell extracts.</p>Formula:C16H15F6N5O·H3PO4·H2OPurity:99.85% - 99.98%Color and Shape:White Or Almost White Crystalline PowderMolecular weight:523.33Latrepirdine dihydrochloride
CAS:<p>Latrepirdine dihydrochloride (Dimebolin dihydrochloride) is an orally active, and neuroactive antagonist of multiple drug targets.</p>Formula:C21H25N3·2HClPurity:98.45%Color and Shape:SolidMolecular weight:392.37Rosuvastatin-d6 Sodium Salt
CAS:<p>Rosuvastatin-d6 Sodium Salt is a deuterated compound of Rosuvastatin Sodium Salt. Rosuvastatin Sodium Salt has a CAS number of 1007871-86-4.</p>Formula:C22H21D6FN3NaO6SColor and Shape:SolidMolecular weight:509.56Irinotecan-d10 Hydrochloride
CAS:<p>Irinotecan-d10 Hydrochloride is a deuterated compound of Irinotecan Hydrochloride. Irinotecan Hydrochloride has a CAS number of 100286-90-6. Irinotecan Hydrochloride is the hydrochloride salt of a semisynthetic derivative of camptothecin. Irinotecan, a prodrug, is converted to a biologically active metabolite 7-ethyl-10-hydroxy-camptothecin (SN-38) by a carboxylesterase-converting enzyme. One thousand-fold more potent than its parent compound irinotecan, SN-38 inhibits topoisomerase I activity by stabilizing the cleavable complex between topoisomerase I and DNA, resulting in DNA breaks that inhibit DNA replication and trigger apoptotic cell death. Because ongoing DNA synthesis is necessary for irinotecan to exert its cytotoxic effects, it is classified as an S-phase-specific agent.</p>Formula:C33H29D10ClN4O6Color and Shape:SolidMolecular weight:633.20Tigecycline-d9
CAS:<p>Tigecycline-d9 is a deuterated compound of Tigecycline. Tigecycline has a CAS number of 220620-09-7. Tigecycline is a broad-spectrum glycylcycline antibiotic derived from tetracycline. Tigecycline binds to the 30S ribosomal subunit, thereby interfering with the binding of aminoacyl-tRNA to the mRNA-ribosome complex.</p>Formula:C29H30D9N5O8Color and Shape:SolidMolecular weight:594.70Lovastatin-d3
CAS:<p>Lovastatin-d3 is a deuterated compound of Lovastatin. Lovastatin has a CAS number of 75330-75-5. Lovastatin is an HMG-CoA Reductase Inhibitor, used for lowering cholesterol.</p>Formula:C24H33D3O5Color and Shape:SolidMolecular weight:407.56VX-702
CAS:<p>VX-702: selective p38α MAPK inhibitor, potent anti-cytokine for rheumatoid arthritis.</p>Formula:C19H12F4N4O2Purity:99% - >99.99%Color and Shape:SolidMolecular weight:404.32MK-5108
CAS:<p>MK-5108 (VX-689) is a highly potent and specific Aurora-A kinase inhibitor with an IC50 value of 0.064 nM.</p>Formula:C22H21ClFN3O3SPurity:99.22%Color and Shape:SolidMolecular weight:461.94Bexarotene
CAS:<p>Bexarotene (LGD1069) is a retinoid analogue that is used to treat the skin manifestations of cutaneous T cell lymphoma (CTCL).</p>Formula:C24H28O2Purity:99% - 99.65%Color and Shape:White SolidMolecular weight:348.48Alisol A
CAS:<p>Alisol A: induces autophagy, anti-cancer, inhibits HepG2, MDA-MB-231, MCF-7 cells.</p>Formula:C30H50O5Purity:99.77% - 99.94%Color and Shape:SolidMolecular weight:490.71Dehydrocorydaline nitrate
CAS:<p>DHC curbs antibody and cell-mediated allergies, inhibits mitochondrial potential in macrophages, and has antinociceptive, anti-inflammatory effects.</p>Formula:C22H24N2O7Purity:99.79% - 99.92%Color and Shape:SolidMolecular weight:428.44Atorvastatin
CAS:<p>Orally active atorvastatin inhibits HMG-CoA reductase, lowers lipids, hinders SV-SMC cell growth, and can up thrombotic risk with clopidogrel.</p>Formula:C33H35FN2O5Purity:99.37% - 99.69%Color and Shape:SolidMolecular weight:558.64BGT226 maleate
CAS:<p>BGT226 maleate (NVP-BGT226) is a class I PI3K/mTOR inhibitor for PI3Kα/β/γ (IC50: 4/63/38 nM) .</p>Formula:C28H25F3N6O2·C4H4O4Purity:97.75% - 98.78%Color and Shape:SolidMolecular weight:650.6Brivanib (alaninate)
CAS:<p>Brivanib Alaninate (BMS-582664) is an alaninate salt of a vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with potential antineoplastic effect.</p>Formula:C22H24FN5O4Purity:99.46% - 99.66%Color and Shape:SolidMolecular weight:441.46Rac-Efavirenz
CAS:<p>Rac-Efavirenz is a non stereospecific structure of Efavirenz.</p>Formula:C14H9ClF3NO2Color and Shape:SolidMolecular weight:315.67Chloroquine dihydrochloride
CAS:<p>Chloroquine: treats malaria, amebiasis, rheumatoid arthritis, lupus; works by inhibiting parasites in red blood cells.</p>Formula:C18H27Cl2N3Color and Shape:SolidMolecular weight:356.33Metyrapone Tartrate
CAS:<p>Metyrapone Tartrate: a test inhibitor for diagnosing Cushing's; blocks steroid 11-beta-hydroxylase.</p>Formula:C22H26N2O13Color and Shape:SolidMolecular weight:526.45Euchrysine 3RX
CAS:<p>Euchrysine 3RX is an agent of bioactive chemicals.</p>Formula:C20H26BrCl2N3OPurity:98%Color and Shape:Brown PowderMolecular weight:475.25Pravastatin
CAS:<p>Pravastatin reduces lipoproteins by blocking HMG-CoA reductase and VLDL synthesis.</p>Formula:C23H36O7Purity:98%Color and Shape:White PowderMolecular weight:424.53Resveratrol analog 2
CAS:<p>Resveratrol analog 2 mimics Resveratrol, a natural antioxidant with anti-inflammatory, cardioprotective, and anticancer benefits.</p>Formula:C16H13FO3Purity:98%Color and Shape:SolidMolecular weight:272.27YT-8-8
CAS:<p>YT-8-8 is a ligand for the p62-ZZ domain and can activate p62-dependent selective autophagy. This compound is also applicable in AUTOTAC design.</p>Formula:C18H23FN2O2Color and Shape:SolidMolecular weight:318.39Erlotinib mesylate
CAS:<p>Erlotinib: reversible inhibitor binding to ATP site of epidermal growth factor receptor.</p>Formula:C23H27N3O7SPurity:98%Color and Shape:SolidMolecular weight:489.54Esmolol hydrochloride
CAS:<p>Esmolol is a cardioselective beta-blocker used in parenteral forms in the treatment of arrhythmias and severe hypertension.</p>Formula:C16H25NO4·HClPurity:98.72% - 99.48%Color and Shape:White SolidMolecular weight:331.15TAMRA alkyne, 6-isomer
CAS:<p>TAMRA alkyne, 6-isomer: a xanthene dye linker with orange emission, used for DNA/RNA labeling, reacts via Click Chemistry.</p>Formula:C28H25N3O4Color and Shape:SolidMolecular weight:467.52Gavilimomab
CAS:<p>Gavilimomab(ABX-CBL) is a murine-derived IgM monoclonal antibody against CD147 antigen used in immunosuppressive treatments for glucocorticoid-resistant GVHD).</p>Purity:95%Color and Shape:LiquidPBA-1105
CAS:<p>PBA-1105, an autophagy-targeting chimeric molecule (AUTOTAC), facilitates the self-oligomerization of p62. Additionally, PBA-1105 enhances the autophagic flux of Ub-conjugated aggregates.</p>Formula:C39H48N2O6Color and Shape:SolidMolecular weight:640.81Seriniquinone
CAS:<p>Seriniquinone is a selective agent of anticancer that acts by inducing cell death via autophagocytosis and targeting the cancer-protective protein dermcidin.</p>Formula:C20H8O4SPurity:98%Color and Shape:SolidMolecular weight:344.34Paroxetine hydrochloride hemihydrate
CAS:<p>Paroxetine hydrochloride hemihydrate (Paxil) is an effective and selective serotonin reuptake inhibitor (SSRI).</p>Formula:C38H44Cl2F2N2O7Purity:99.949%Color and Shape:SolidMolecular weight:749.67SU11274
CAS:<p>SU11274 (Met Kinase Inhibitor)(IC50=10 nM) is a specific Met inhibitor. It shows no significant effects on PGDFRβ, EGFR or Tie2.</p>Formula:C28H30ClN5O4SPurity:98.62% - 99.53%Color and Shape:Orange PowderMolecular weight:568.09Metofenazate
CAS:<p>Metofenazate is an selective inhibitor of calmodulin .</p>Formula:C31H36ClN3O5SPurity:98%Color and Shape:SolidMolecular weight:598.15CXCR3 Antagonist 6c
CAS:<p>CXCR3 antagonist 6c blocks CXCR3 and inhibits Ca2+ movement and T-cell migration (IC50: 0.06 µM & 100 nM) with selectivity over 14 other GPCRs.</p>Formula:C30H32Cl3N5O3Color and Shape:SolidMolecular weight:616.97Momelotinib Mesylate
CAS:<p>Momelotinib Mesylate is an ATP-competitive JAK1/JAK2 inhibitor (IC50: 11 nM/18 nM). It has 10-fold selectivity versus JAK3.</p>Formula:C24H26N6O5SPurity:98%Color and Shape:SolidMolecular weight:510.57MF-095
CAS:<p>MF-095 is a control probe for MF-094, which is a potent inhibitor of ubiquitin specific protease 30.</p>Formula:C27H31N3O4SColor and Shape:SolidMolecular weight:493.62(3S,5R)-Rosuvastatin
CAS:<p>(3S,5R)-Rosuvastatin is the (3R,5R)-enantiomer of Rosuvastatin. Rosuvastatin is a competitive HMG-CoA reductase inhibitor (IC50: 11 nM).</p>Formula:C22H28FN3O6SPurity:98%Color and Shape:SolidMolecular weight:481.54p38 MAPK-IN-2
CAS:<p>p38 MAPK-IN-2 is an inhibitor of p38 kinase.</p>Formula:C20H19ClFN5O2Purity:98%Color and Shape:SolidMolecular weight:415.85HF50731
CAS:<p>HF50731 is a CXCR4 antagonist with high binding affinity (IC50: 19.8 nM) and inhibits calcium mobilization, cell migration, and HIV-1 (IC50: 1.5 nM).</p>Formula:C26H46N4Color and Shape:SolidMolecular weight:414.67ATG7-IN-2
CAS:<p>ATG7-IN-2 inhibits ATG7 protein with 0.089 μM IC50 and suppresses autophagy marker LC3B.</p>Formula:C11H16N6O7SColor and Shape:SolidMolecular weight:376.35GLPG2451
CAS:<p>GLPG2451 potentiates F508del CFTR at low temp (EC50: 11.1 nM), aiding cystic fibrosis treatment.</p>Formula:C16H16F3N3O5SColor and Shape:SolidMolecular weight:419.38SMER18
CAS:<p>SMER18, a small molecule enhancer of rapamycin, acts as an mTOR-independent inducer of autophagy and can be used to study neurodegenerative diseases.</p>Formula:C16H14ClNO2Purity:97.27%Color and Shape:SolidMolecular weight:287.74Omeprazole Sodium
CAS:<p>Omeprazole Sodium is a proton pump inhibitor(PPI) and suppresses gastric acid secretion.</p>Formula:C17H18N3NaO3SPurity:99.84%Color and Shape:Clear In WaterMolecular weight:367.4Ivacaftor hydrate
CAS:<p>Ivacaftor hydrate is an orally bioavailable CFTR potentiator. It also is used for cystic fibrosis treatment.</p>Formula:C24H30N2O4Purity:98%Color and Shape:SolidMolecular weight:410.514CXCR4 antagonist 5
CAS:<p>CXCR4 antagonist with IC50 of 8.8 nM, inhibits CXCL12-induced calcium increase and chemotaxis, with good safety and minimal CYP, hERG impact.</p>Formula:C21H30N6Color and Shape:SolidMolecular weight:366.5Poloppin
CAS:<p>Poloppin modulates polo-like kinases, targets mutant KRAS, and enhances Crizotinib's effects against KRAS-mutant cancers.</p>Formula:C20H15BrF3NO2Purity:98%Color and Shape:SolidMolecular weight:438.24PF-06455943
CAS:<p>PF-06455943: LRRK2 inhibitor, IC50=3nM, PET radioligand, used for ADME/neuro PK & Parkinson's research.</p>Formula:C17H14FN5OColor and Shape:SolidMolecular weight:323.32Ivacaftor benzenesulfonate
CAS:<p>Ivacaftor benzenesulfonate used for cystic fibrosis treatment. is an orally bioavailable CFTR potentiator.</p>Formula:C30H34N2O6SPurity:98%Color and Shape:SolidMolecular weight:550.67eIF4A3-IN-2
CAS:<p>eIF4A3-IN-2 is a highly selective and noncompetitive eukaryotic initiation factor 4A-3 inhibitor with an IC50 of 110 nM.</p>Formula:C25H19Br2ClN4O2Purity:98%Color and Shape:SolidMolecular weight:602.71Ralimetinib
CAS:<p>Ralimetinib blocks MK2 phosphorylation at Thr334 without affecting p38α MAPK or JNK. It is an ATP-competitive inhibitor of p38 MAPK α/β (IC50 5.3/3.2 nM).</p>Formula:C24H29FN6Purity:99.16% - 99.21%Color and Shape:SolidMolecular weight:420.53PF-06371900
CAS:<p>PF-06371900 is a potent and highly selective inhibitor of leucine-rich repeat kinase 2 (LRRK2).</p>Formula:C17H16N6O2SColor and Shape:SolidMolecular weight:368.41Lamotrigine isethionate
CAS:<p>Water-soluble salt of lamotrigine . Displays anticonvulsant effects and inhibits glutamate release, possibly through inhibition of Na+, K+ and Ca2+ currents.</p>Formula:C11H13Cl2N5O4SColor and Shape:SolidMolecular weight:382.22SR 3677 dihydrochloride
CAS:<p>Potent and selective Rho-kinase inhibitor (IC50 values are 3 and 56 nM for ROCK-II and ROCK-I respectively).</p>Formula:C22H26Cl2N4O4Color and Shape:SolidMolecular weight:481.37NSC 33994
CAS:<p>NSC 33994 is a selective inhibitor of JAK2 (IC50 = 60 nM). It also shows no effect on Src and TYK2 tyrosine kinase activity at a concentration of 25 μM.</p>Formula:C28H42N2O2Purity:98%Color and Shape:SolidMolecular weight:438.65CXCR4 modulator-2
CAS:<p>CXCR4 modulator-2 (Z7R) has high potency (IC50: 1.25 nM), stable in mouse serum (t1/2=77.1 min), and anti-inflammatory in mice.</p>Formula:C21H32N8O2Color and Shape:SolidMolecular weight:428.53SMYD3-IN-2
<p>SMYD3-IN-2, a cancer research chemical, inhibits SMYD3 (IC50 0.81 μM) and BGC823 (IC50 0.75 μM), inducing fatal autophagy in gastric cancer.</p>Formula:C26H21BrN2O4Color and Shape:SolidMolecular weight:505.36Quinacrine analog 34
CAS:<p>Quinacrine: anti-protozoal, autophagy inhibitor (toxic at 2.5 μM). Analog 34 less toxic (LD50 = 27 μM), raises LC3-II protein, deacidifies lysosomes.</p>Formula:C20H27ClN4Color and Shape:SolidMolecular weight:358.91
